Podcasts about mri

All about Fibromuscular Dysplasia; Early morning night sweats; Local COVID-19 testing facilities and latest treatment drugs and their drug interactions; A new much lower power and cheaper MRI machine show promise for poorer countries; Detoxification benefits of broccoli and brussels sprouts -- sulforaphane is the key; Diseases such as ALS and MS may be caused by endogenous retroviruses -- Anti-retroviral drugs may help

This week we review a recent CMR study assessing changes in myocardial fibrosis identified with CMR T1 mapping seen in TOF patients with a single nucleotide polymorphism (SNP) of hypoxia inducible factor 1 alpha. Is myocardial fibrosis in the TOF patient due to hemodynamic factors alone or are there genetic factors that predispose to differences that can be measured on CMR? Professor Lars Grosse-Wortmann of OHSU shares his deep insights into this fascinating topic in which our understanding is rapidly evolving. doi: 10.1016/j.ijcard.2021.12.047

This week's View highlights the use of ICD therapy in ischemic vs. non-ischemic cardiomyopathy; what are the (FDG)-positron emission tomography (PET) and MRI findings, and abnormalities in patients with COVID-19; and a meta-analysis examining oral anticoagulation in AFib.

What immediately comes to mind when you think of schizophrenia? Most people would say hallucinations. Hallucinations, at least according to pop culture, are the defining feature of schizophrenia. But is that true?  Today's episode discusses how many people living with schizophrenia hallucinate and if hallucinations are all the same. Do people in different countries or from different backgrounds hallucinate differently? Join us to learn the answers to these questions and more! Guest Bio Paul Fitzgerald, PhD completed his medical degree at Monash University and subsequently a Master of Psychological Medicine whilst completing psychiatric training. He then undertook a Clinical and Research Fellowship at the University of Toronto and The Clarke Institute of Psychiatry, Toronto, Ontario, Canada. On returning to Melbourne, he worked as a psychiatrist and completed a PhD in transcranial magnetic stimulation in schizophrenia. Since completing this PhD, he has developed a substantial research program including a team of over 25 psychiatrists, registrars, postdoctoral researchers, research assistants, research nurses, and students. Professor Fitzgerald runs a research program across both MAPrc and Epworth Clinic using brain stimulation and neuroimaging techniques including transcranial magnetic stimulation, functional and structural MRI, EEG, and near infrared spectroscopy. The primary focus of this program is on the development of new brain stimulation-based treatments for psychiatric disorders. Visit him online at www.paulbfitzgerald.com. Inside Schizophrenia Podcast Host Rachel Star Withers creates videos documenting her schizophrenia, ways to manage and let others like her know they are not alone and can still live an amazing life. She has written Lil Broken Star: Understanding Schizophrenia for Kids and a tool for schizophrenics, To See in the Dark: Hallucination and Delusion Journal. Fun Fact: She has wrestled alligators. To learn more about Rachel, please visit her website, RachelStarLive.com. Inside Schizophrenia Co-Host Gabe Howard is an award-winning writer and speaker who lives with bipolar disorder. He is the author of the popular book, "Mental Illness is an Asshole and other Observations," available from Amazon; signed copies are also available directly from the author. Gabe makes his home in the suburbs of Columbus, Ohio. He lives with his supportive wife, Kendall, and a Miniature Schnauzer dog that he never wanted, but now can't imagine life without. To learn more about Gabe, please visit his website, gabehoward.com.

This week, Jessica is being hunted by the UK Police and unfortunately, June's voicemail is still full. Jessica updates us about her MRI experience and discusses struggles around being too agreeable, while June shares how her dog, Sgt. Meatball helps her regulate her energy. Then, the gals discuss the continuing struggle parenting in a pandemic, Jessica reveals her new go-to small talk initiations, and June tries to convince Jessica she's good at small talk too, but the jury is still out on that. And Deep Divers, remember to be responsible for your own energy.  Virtual tickets for New Year New Jane retreat can be found here  https://www.janeclub.com/new-year-new-jane Code : DEEPDIVE20X  Visit the Pinterest Board pinterest.com/thedeepdiveYou can follow The Deep Dive on Twitter @thedeepdivepodJune Diane Raphael @MsJuneDiane on Twitter @junediane on InstagramJessica St. Clair @Jessica_StClair on Twitter @stclairjessica on InstagramCheck out the Jane Club at www.janeclub.comSend us your The Deep Dive theme or any questions you might have to thedeepdive@earwolf.com

EMRs contribute to HCW burnout, are disruptive to workflows, contribute to alarm fatigue, decrease patient contact time, and are a way for hospitals to bill. But also... EMRs are better at trending care, reduce prescribing errors, measure social determinants of health. Do Laura and Abby like the EMR? Do they hate the EMR? is the EMR Laura and Abby's frenemy? No one knows, but they definitely have a lot of questions like: Is the EMR a billing software? Do scribes increase RVUs? Should there be price transparency in the EMR? Should patients get immediate access to results? Definitely good that patients can carry their records around with them.. right? Healthcare systems don't have the infrastructure to do counselling, so do patients get results and then not have a provider to talk to them about it? Is it paternalism to think all doctors break bad news well? What if a patient finds out they have cancer from checking their MRI reports at home? New season, new cohost.⁣ I

Dr. Cristin A. Dickerson is the founding partner of Green Imaging. Dr. Dickerson was born and raised in Texas. She is a graduate of Baylor University and University of Texas Medical School at Houston where she was elected to Alpha Omega Alpha Honor Medical Society. Dr. Dickerson did a clinical internship at St. Joseph Hospital in Houston and her radiology residency at UT Houston where she was a chief resident, with extensive training in cancer imaging at MD Anderson Cancer Center. Dr. Dickerson practiced 13 years at Diagnostic Clinic of Houston where she served as two-term president of the 50 physician clinic. Her clinical interests include oncologic (cancer) MRI and CT and PET/CT, breast imaging and cardiac screening. She founded Green Imaging to provide affordable, high-quality medical imaging for uninsured and high deductible patients in Houston and rapidly expanded the company to provide services throughout most of the US and to employer-sponsored health plans. She loves being able to provide quality services to patients who otherwise couldn't afford it and providing significant imaging cost savings to patients with healthcare coverage and their employers without compromising quality. Dr. Dickerson is passionate about spreading the word that patients and employers do have great new nontraditional health care coverage options in the emerging alternative health care market. Unlock Bonus content and get the shows early on our Patreon Follow us or Subscribe: Apple Podcasts | Google Podcasts | Stitcher | Amazon  | Spotify --- Show notes at https://rxforsuccesspodcast.com/86 Report-out with comments or feedback at https://rxforsuccesspodcast.com/report Music by Ryan Jones. Find Ryan on Instagram at _ryjones_, Contact Ryan at ryjonesofficial@gmail.com  

Resources:https://releasemuscletherapy.com/How are you feeling today? If you have had a recent injury, you are probably experiencing pain. You may have had tests like an MRI or X-ray to identify the damage and to determine what course of action needs to be taken to heal. Physical therapy, spinal adjustments or exercises may have been prescribed to aid in the healing process. After following instructions, within several months, your tissues will be healed, and you should be pain free. But wait, what happens when you have followed all your doctors' instructions, 6 months have passed, and you are still in pain? You have advanced from acute pain to chronic pain. Today, Sam Visnic, a clinical massage therapist and owner of Release Muscle Therapy is with me to talk to you about how he treats clients with chronic pain. For “18 years he has studied dozens of systems and methodologies for uncovering the root cause of aches and pains”. Pain is complex. It involves many factors that extend beyond just muscles and joints. Sam's program addresses these factors in a systemic way that gets lasting results. Everyone is unique in the way they experience pain and Sam tailors each session to the specific needs of each client.Tune in today to hear:-How the brain processes information about pain.-How clinical massage can change how the brain interprets that information.-Info about Fibromyalgia and how he treats it: a syndrome of increased or maladaptive responsive to stress. -How all the systems of the body are integrated and can affect our perception of pain.-Sam's Free Insider group: Sign up for access to free resources and effective tools for pain relief, including his book “Why Didn't My Doctor Tell Me That?” -Look for Sam's new Podcast “Who knows this”Direction Not Perfection Resources:www.healthaccountabilitycoach.comwww.facebook.com/houselifestyles

On this week's episode, the guys discuss how they'd do in an MRI machine, Aaron joins the weight loss challenge and Nate talks about his recent appearance on the Tonight Show with Jimmy Fallon. Then comedian Henry Cho joins them to talk about his start in comedy in the 80's, doing chicken wire gigs, being the first comic to appear on The Tonight Show with Jay Leno, and his friend the late great Bob Saget.    Podcast produced by Nate & Laura Bargatze https://www.natebargatze.com https://www.allthingscomedy.com https://www.genovationsdesign.com https://www.centerstmedia.com Email - Nateland@NateBargatze.com #nateland #natebargatze   Helix - HelixSleep.com/Nate Helix is offering up to 200 dollars off all mattress orders AND two free pillows for our listeners at Helix Sleep.com/NATE. That's up to 200 dollars off all mattress orders AND two free pillows at Helix Sleep.com/NATE.     Vuori  - VuoriClothing.com/Nate ·     Vuori is an investment in your happiness.  ·     For our listeners they are offering 20% off your first purchase.  ·     Get yourself some of the most comfortable and versatile clothing on the planet at VUORI CLOTHING.COM/NATE ·     Not only will you receive 20% off your first purchase, but enjoy free shipping on any U.S. orders over $75 and free returns.  ·       Go to VUORI CLOTHING.COM/NATE and discover the versatility of Vuori Clothing.   Indeed -  Indeed.com/Nate   Start hiring RIGHT NOW with a SEVENTY-FIVE DOLLAR SPONSORED JOB CREDIT  to upgrade your job post at Indeed.com/NATE. Offer valid through March 31st. Go to Indeed.com/NATE to claim your SEVENTY-FIVE DOLLAR CREDIT before March 31st. Indeed.com/NATE. Terms and conditions apply. Need to hire? You need Indeed.   DraftKings -    Download the DraftKings Sportsbook app now, use promo code NATELAND, and get FIFTY SIX TO ONE ODDS on any NFL team.  Bet just FIVE DOLLARS and win TWO HUNDRED EIGHTY IN FREE BETS if your team wins.  That's promo code NATELAND this Wild Card weekend at DraftKings Sportsbook — an Official Sports Betting Partner of the NFL.   Must be 21 or older, NJ, IN, or PA only.  New customers only. Min. $5 deposit and $1 wager required.  One per customer. Restrictions Apply.  See draftkings dot com slash sportsbook for details.  Gambling problem? Call 1-800-GAMBLER. See omnystudio.com/listener for privacy information.

Today's guest is Betsy, from an organization called Hope for HIE (Hypoxic Ischemic Encephalopathy). HIE refers to brain injury in an infant, and Betsy will share more specifics about the condition and her family's experience with it  in our discussion. I originally learned about this organization through working in the NICU here in Texas, and it is a wonderful source of support for parents struggling in completely unknown territory with their babies. In this episode, we talk about… [1:19] HIE: Hypoxic Ischemic Encephalopathy [2:29] Betsy's family [3:02] The beginning of the HIE journey [11:36] Brain cooling (therapeutic hypothermia) [15:10] Seeing your baby in the NICU [24:06] Warming after therapeutic hypothermia [24:41] MRI day and diagnosing the severity of HIE [30:58] Leaving the NICU [36:01] Moving forward with career and family as parents of a child with HIE [41:20] A current update on Betsy's son and family Connect with Betsy: Website Instagram Facebook Have you heard?  The Child Life On Call mobile app for parents, kids and their care team will be available in 2022.  Sign up to stay informed here. Child Life On Call is a community of parents and professionals that share ideas, stories and resources to help YOU navigate your child's unique experiences. We give you strategies to support yourself and your family through life's challenges.  We are so glad you are here. Website: childlifepodcast.com Merch: bonfire.com/store/childlifeoncall Instagram: instagram.com/childlifeoncall Facebook: facebook.com/childlifeoncall Twitter: twitter.com/childlifeoncall YouTube: https://www.youtube.com/channel/UCnh95T1MOYtbpBxJaZqg7rg

Dodging them omicrons, deltacrons, and unicrons, we're back on the zoom this week! Notes: We're still in a pandemic! Dodging bullets and man there's a lot of bullets out there! Matinees suck! Pizza party dinner theatre! We hope you came for a long matinee digression cause that's what you're getting! Jaq can no longer sit by and allow Will's disregard for matinee crowds to go unchallenged! Will gets censured! We got them ads! Nelson needs some skin in the game! Nelson watched Succession and Will watched the Expanse! We both watched Boba Fett! Will's spa corner! Go to Salon Lotus for your spa days and Diagnostic Imaging Center for your MRI needs! Contact Us! Follow Us! Love Us! Email: doubledeucepod@gmail.com Twitter & Instagram: @doubledeucepod Facebook: www.facebook.com/DoubleDeucePod/ Also, please subscribe/rate/review/share us! We're on iTunes, Android, Libsyn, Stitcher, Google, Spotify, Radio.com, RadioPublic, pretty much anywhere they got podcasts, you can find the Deuce! Podcast logo art by Jason Keezer! Find his art online at Keezograms! Intro & Outro featuring Rob Schulte! Check out his podcasts at Pink Jeans! Brought to you in part by sponsorship from Courtney Shipley, the foul cur Applebee's, Amber Fraley's new novel The Bug Diary, and listeners like you! Patreon launching soon! Check out the Lawrence Times's 785 Collective at https://lawrencekstimes.com/785collective/ for a list of local LFK podcasts including this one! Do you like reading? Sure, we all do! Then you should read Amber Fraley's debut novel, The Bug Diary, from Anamcara Press! It's a hilarious coming-of-age college romp and a mysterious ghost story rolled into one by an authentic, relentless, amazing writer who also happens to be a fan of this podcast! Available at the Raven Bookstore, anamcara-press.com, or contact Amber Fraley, Author on facebook!

Folks, we're back together again as we hear the scientific reason why dogs were given an MRI, the Tennessee poltician who tried to pants a ref at a high school basketball game, how the record for the biggest hair ball was set, the man suing two NFL teas for not actually being located in New York, and the malfunction that led to a town being covered in soy beans We are on Patreon! Become a patron for weekly bonus eps and more stuff!: www.patreon.com/whatatimepod Check out our YouTube channel: https://www.youtube.com/c/whatatimetobealive Get one of our t-shirts, or other merch, using this link! https://whatatimepod.bigcartel.com/ whatatimepod.com Join our Discord chat here: discord.gg/jx7rB7J @pattymo // @kathbarbadoro // @eliyudin // @whatatimepod © 2021 What A Time LLC

Are you curious about the trends and predictions for 2022 and how they will affect physical therapy? Here are the seven things I see that will impact how we will be doing business in the new year.1) Alternative Streams of revenue. You need to build multiple streams of revenue for yourself, even if you just have 1 or 2 waiting to be your next thing. What are the ways you can diversify your income? Maybe one of these things will be your focus later. 2) PT's will be demanding higher salaries.You'll need to figure out a way to help your employees earn more, especially if you want to keep them as amazing employees. You also may need to figure out haw to pay yourself more! If you're only charging $150 an hour, you're going to have a hard time paying your employees what they're worth, or even making a profit. You have to incentivize the position! 3) Facebook ads are harder and more expensive This is why having a proven offer and solid email marketing follow up system is more important than ever. This needs to be in place BEFORE you run ads. And it's only going to get harder and harder. Facebook is a moving target. What's better than Facebook ads? The system that comes behind it. An automated email system is vital to eventually converting the leads that don't initially convert. If you can't follow up, you can't convert.   4) More people than ever are getting sickNot just with covid, and have metabolic disease. Patients think that they need an MRI, or surgery, or a medication to ever feel good again. And who is better to educate the public than a doctor of physical therapy. It's not just fixing back pain, it's fixing mindset. 5) CovidThis is the way it is and it will never be the way it was. Get over it. Start living and planning for what's coming next. What's your next move? People still need our help as physical therapists. If we're not in the conversation, then we don't matter.  6) Online businessesMore PT's starting online businesses, not just cash practices. More people are starting to start businesses and making money online. We've had dozens and dozens of people come through our courses in the last quarter. Don't wait! Start building a social media presence and a following now!  People come into it and get upset they don't make $10,000 a month in the first year. Things take time to grow! But there's no better time to start than now! 7) InflationYou need to find a way to increase your income more than inflation. Sell an online course, teach a group class, do some coaching, ask for a raise. if you own a cash practice and you're feeling it you are not charging enough already. You have to figure out how to leverage other people's money to make more money.  Sales is the hard work. Most people rather market more instead of sell more. But you don't need more marketing. You need to sell.     Connect with Aaron: https://www.facebook.com/AaronLeBauer (Facebook) https://www.instagram.com/aaronlebauer/ (Instagram) https://www.facebook.com/groups/CashPTNation (CashPT Nation Facebook Group) If you are ready to launch and grow a Cash PT practice, https://www.instagram.com/aaronlebauer/ (DM me) “Blueprint” to get started!Plus: Whenever you're ready… here are 3 ways I can help you grow your coaching business: Grab a free copy of my https://www.lebauerconsulting.com/store/ (book) It's the road map to launch, grow & scale your physical therapy business.http://www.cashptblueprintbook.com/ ( -> Click Here) Join our CashPT Blueprint Program and be a Case Study. I'm putting together a new coaching case study group this month and if you'd like to work with me on your client-getting and scale plans… just send me a message at https://m.me/AaronLeBauer (m.me/AaronLeBauer) with the words “Blueprint”. Work with me and my team privately If you'd like to work directly with me and my team to take you to 6 or 7 figures… just send me a message athttps://m.me/AaronLeBauer ( m.me/AaronLeBauer)...

Lindsey is a PT and also competed as a 4-year scholar-athlete playing soccer. Furthering her career she became a board-certified Orthopedic Clinical Specialist in 2016.  She then completed the University of Chicago Medicine Orthopedic Manual Therapy Fellowship in 2019.    Her clinical and research interests include treating runners and triathletes, people with chronic and persistent pain, and people with femoroacetabular impingement (FAI) syndrome.   She is an avid marathon runner and long-course triathlete and It was her own hip journey with FAI and a labral tear that sparked her interest in helping others with hip issues get back to doing the things they love. We dive into the definition, pathology and clinical signs of FAI along with the likely contributing factors in running. Brodie and Lindsey also discuss the prevalence of incidental findings with MRI scans and the asymptomatic prevalence within the healthy community. Lindsey also shares the common misconceptions about this condition, rehabilitation advice and treatment. We also answer your patron questions including the risks of running with FAI and the likelihood of developing other running-related injuries if untreated.  Instagram is: @plassptperformance  website: plassptperformance.com email: lindsey@plassptperformance.com Become a patron! Receive Run Smarter Emails Book a FREE Injury chat with Brodie Run Smarter App IOS or Android  Podcast Facebook group Run Smarter Course with code 'PODCAST' for 3-day free trial.

UFC Fighter, Matt Brown, comes on the show today to announce his next fight and it is here in Columbus. A listener butt dialed his ex for 11 minutes and now his wife wants to look through his phone, but he doesn't think he should have to let her and wants our advice. Randi takes another Covid test on the air, but this time she swabs her throat. Kelly Quinn is getting a new puppy. Plus, taste and smell, new Vegas restaurants, Antonio Brown's MRI, color changing BMW, Ghislaine Maxwell, Powerball and more!

Expensive watches have been a status symbol for centuries, but now, weird-looking bands have replaced the bingy Rolexes. Instead of signaling wealth, these new gizmos signal a keen interest and commitment to health. Welcome to the world of wearable health tech. On a basic level, you can track your daily steps and your heart rate. More advanced devices can track respiratory rate, HRV, body temperature, and even blood oxygen levels. Wearable health tech has made huge strides forward recently, and many consumer devices can now hold their own with clinical-grade equipment. My guest on this week's show is a quantified scientist who will help us learn to measure, track and improve our health.  Learn Best health tracker for under $100 Best health tracker if money is not an issue  Best sleep tracking device What we really know about the microbiome Weekly brain MRI's LinksRob's Website Rob's YouTube Channel ABOUT OUR GUESTRob ter Horst is a postdoctoral researcher who studies the immune system using bioinformatics which includes machine learning and statistics. Rob is neck deep in the quantified self movement. He measures and tracks everything in his life, a laborious task that demands 11 hours a week and includes a weekly brain MRI, sleep EEG and gut microbiome composition tests. ​  Nutritional Tip of the Week Calorie Counting Like the Show? Leave us a Review on iTunes

In this radiology lecture, we discuss the CT and MRI appearance of perihilar cholangiocarcinoma. Key points include: Perihilar cholangiocarcinoma (AKA The post Case Review: CT & MRI of Perihilar Cholangiocarcinoma (Klatskin Tumor) appeared first on Radiologist Headquarters.

It's 2022 and we're coming in with a lot of clips, clops and emotions, and all we ask is that you LET US LIVE. Jessica dives right in it by sharing some personal news and the gals dig into the fears that are kept locked up tight in the closet. Then, June shares her MRI journey, and reveals that 2022 means accepting she needs glasses, if only to watch her ‘stories'. Deep Divers, let's get excited for the New Year and let‘er rip!  Visit the Pinterest Board pinterest.com/thedeepdiveYou can follow The Deep Dive on Twitter @thedeepdivepodJune Diane Raphael @MsJuneDiane on Twitter @junediane on InstagramJessica St. Clair @Jessica_StClair on Twitter @stclairjessica on InstagramCheck out the Jane Club at www.janeclub.comSend us your The Deep Dive theme or any questions you might have to thedeepdive@earwolf.com  

Career and recruitment expert Bert E. Miller, CEO of Protis Global and MRI NetworkWebsite: https://bertmiller.com/Company Website: https://protisglobal.com/With over 25 years of leadership experience in the world of work, Bert E. Miller currently serves as CEO of Protis Global , Ace Talent Curators, and President and CEO of MRI Network, a network-centric recruitment organization that offers consulting, training, contract staffing, and community building to over 325 search firms worldwide. Bert's expertise in search and recruitment dates back to 1995, when he co-founded Protis Global, an MRINetwork member and award-winning search and recruitment firm specializing in the F&B, CPG, cannabis, and hospitality industries. Protis Global has built some of the most iconic brands in the CPG space, and has consistently ranked in the top 10 of MRINetwork offices over the last 15 years, generating over $75M in permanent placement fees. In 2019, Bert acquired MRI to lead the organization and its global offices through digital transition and into a new era of talent access. His vision is to effectively scale MRI's unique network model while supporting existing members with proven tools, training, digital media products, and technology. Bert is an entrepreneur, active speaker, mentor, advisor, and investor. He hosts the MRINetwork Podcast and his new video podcast series, Beyond the Bottom Line, debuts this fall in which he will be interviewing CEOs and leaders from across categories on issues impacting the world of work.Rebel HR is a podcast for HR professionals and leaders of people who are ready to make some disruption in the world of work.We'll be discussing topics that are disruptive to the world of work and talk about new and different ways to approach solving those problems.Follow Rebel HR Podcast at:www.rebelhumanresources.comhttps://twitter.com/rebelhrguyhttps://www.facebook.com/rebelhrpodcastwww.kyleroed.comhttps://www.linkedin.com/in/kyle-roed/Buzzsprout - Let's get your podcast launched! Start for FREEDisclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the show (https://www.buymeacoffee.com/rebelhrpodcast)

In this episode, CardioNerds (Amit Goyal), ACHD series co-chair,  Dr. Josh Saef (ACHD fellow at University of Pennsylvania) and episode lead fellow, Dr. Brynn Connor (Pediatric Cardiology fellow at Lucile Packard Children's Hospital at Stanford) are joined by Dr. Maan Jokhadar (Advanced heart failure and adult congenital heart disease specialist at Emory University) to discuss transposition of the great arteries. Audio editing by CardioNerds Academy Intern, Dr. Maryam Barkhordarian. For a brief review of the basic anatomy and physiology of D-TGA, check-out this great video by Dr. Maan Jokhadar! The CardioNerds Adult Congenital Heart Disease (ACHD) series provides a comprehensive curriculum to dive deep into the labyrinthine world of congenital heart disease with the aim of empowering every CardioNerd to help improve the lives of people living with congenital heart disease. This series is multi-institutional collaborative project made possible by contributions of stellar fellow leads and expert faculty from several programs, led by series co-chairs, Dr. Josh Saef, Dr. Agnes Koczo, and Dr. Dan Clark. The CardioNerds Adult Congenital Heart Disease Series is developed in collaboration with the Adult Congenital Heart Association, The CHiP Network, and Heart University. See more Claim free CME for enjoying this episode! Disclosures: None Pearls • Notes • References • Guest Profiles • Production Team CardioNerds Adult Congenital Heart Disease PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! https://www.youtube.com/watch?v=Ifu8nVtXT_c Pearls (1) In D-TGA following an atrial switch operation, the right ventricle IS the systemic ventricle! (2) Evaluation of systemic right ventricular function often requires use of both transthoracic echocardiography and cardiac MRI. (3) Use of medical heart failure therapies should be individualized, without any proven long-term mortality benefit and potential unique complications in this patient population (i.e. SA node dysfunction).  Show notes D-transposition of the great arteries (D-TGA) is one of the most common forms of cyanotic congenital heart disease presenting in the newborn period. Anatomically, d-transposition of the great arteries is characterized by atrioventricular concordance and ventriculoarterial discordance, such that the aorta arises from the morphologic right ventricle and pulmonary artery arises from the morphologic left ventricle. The resultant physiology is that of a parallel circulation, with deoxygenated blood recirculating in the systemic circulation (via the RA-RV) and oxygenated blood recirculating in the pulmonary circulation (via the LA-LV). At birth, this invariably results in cyanosis, with survival dependent upon adequate mixing of the two circulations via an atrial or ventricular level defect. Prior to surgical advances in the late 1950s, this lesion was uniformly fatal, with most infants dying before their first birthday. The subsequent development of the Senning and Mustard atrial-level repairs led to good immediate outcomes and improved long-term survival. However, following these “physiologic” types of repair, patients are far from cured, with several long-term established complications, including (1) dysfunction of the systemic right ventricle, (2) tricuspid regurgitation (the systemic atrioventricular valve), (3) atrial and ventricular arrhythmias, and (4) systemic and pulmonary venous baffles leaks and obstruction. These complications ultimately lead to substantial morbidity and premature mortality, with ACHD providers facing unique challenges in the medical and surgical management of this heterogenous patient population. 1. What are the basic anatomic features of d-transposition of the great arteries (d-TGA)?

Don't look up was good. leon the professional was ok. everything must go is kind of dark but good. people get kicked out of the bar for no reason now. asian jon was in town. i got an MRI. 

Check it out on YT --->  2021 Wrap up and RSNA Take ways!In this quick episode of Zone 3 Podcast, Robert and Reggie Review their Takeaways from RSNA 2021 and Hint at some of their projects that will be released in 2022.  MR Arcade --> Coming MRI Job Listing --> ComingMRI Animated Series --> Coming Keep up to date with our Ongoing project @ Zone3podcast.comThank you all for all your Support. 2022 is going to be a great year.  Stay tuned. About our Sponsor:  Aegys is an innovative leader in the MRI safety industry and the Creator of The TechGate Automatic.Aegys is committed to providing innovative product and process solutions that enhance overall magnet safety and improve efficiency.  TechGate Auto is a Zone 4 Barrier System that keeps patients and MRI technologists safe.  TechGate Auto allows technologists to focus on the care of patients and efficient room turnaround rather than worrying about anyone entering the MRI room behind them. Easy to use and designed for the MRI environment, TechGate Auto is deployed whenever the technologist enters or leaves the MR room or via push-button remote control, providing an immediate physical restriction of access to all unauthorized individuals.The use of a “caution” barrier at the entrance to the MR room is now a recommendation of the American College of Radiology MR Safety Committee.Links Aegys' Tech Gate Auto-  https://aegysgroup.com/

This episode contains: No Steven this week, but Devon and Ben make do. Devon got his son a Lego Hogwarts castle. Ben thought we'd be without Lego talk with Steven not on the show. He was wrong. Devon practiced an hour to pitch in a VR baseball game, and still sucks. Oooh girl, shock me like an eletric eel: Here's how to give an electric eel an MRI. Ben talks about how to give an electric eel an MRI. Devon asks "Why?" but still thinks eel skeletons are pretty metal. An anesthesized eel can still drown... How do vets keep them breathing? Ever wanted to know how to reconstruct a blown knee on a bullfrog? https://arstechnica.com/science/2021/12/how-to-give-an-electric-eel-an-mri/ Here comes the sun!: A spacecraft has 'touched' the sun for the first time. NASA's Parker Solar Probe spent five hours in the sun's corona. WOW! Devon talks about Alfvén critical waves, theorized in 1942 and proven in 2019. Turns out the corona is far hotter than the surface of the sun. NASA's Parker Solar Probe is the fastest known object built by humans. https://www.sciencedaily.com/releases/2021/12/211214134947.htm Science Fiction: Doom Patrol season 3 was crazy! Devon and Ben really liked it. Devon is caught up on season 4 of Star Trek: Discovery, but skipped season 3. We talk future airdates for Star Trek: Discovery, Prodigy and Picard in early 2022. Ben and Devon wrap it up with a low-spoiler chat about The Matrix Resurrections.

I often get questions from runners and this is actually a common one that I get from runners when they have either enrolled in the plantar plate sprain treatment course for runners, or if they've signed up to do an individual webcam consultation. Everybody seems to think that an MRI will give you a crystal clear image of what's going on inside your body and in some sense, that's true. It is amazing, the amount of detail you can get when you get an MRI. However, you have to remember that the plantar plate ligament is a very small structure and when you get an MRI, it doesn't necessarily show everything. Is it okay to run before I get an MRI of a plantar plate sprain? That's a great question and that's what we're talking about today on Doc On The Run Podcast.

Trova il percorso is a sixth level divination which is cast upon the self, with a casting time of one minute, a duration of one day, a material requirement of a ferrous material such as iron or steel, and requires concentration to maintain. This spell allows one to become sensitive to magnetic fields, most notably, that of the Earth.  With practice, one can feel the direction of magnetism and follow it for navigation.  This skill is also useful for treasure hunters, and surveyors as metallic objects disrupt the flow of natural magnetic lines.  Caution must be taken to not cast trova il percorso near unnaturally strong magnetic fields such as found in a Magnetic Resonance Imaging machine or MRI.  Doing so will cause an instant migraine and in some cases, unconsciousness.  Trova il percorso was discovered in Italy in 1874 and immediately became useful in locating bullets and shrapnel from human patients.  Masters of the spell can use it to find specific ores and metals such as gold and silver.  Grandmaster Dr. Gerhard Fischer of Landshut, Germany is so attuned to magnetic fields that he can sense a grain of gold from a distance of one thousand feet.

Oppa still on Christmas Vacation style! The boys are back at it again with some YKS Premium Freemium content: an unearthed, probably-new-to-you classic, our interview (?) and Bloody Mary sesh with Birthday and Sloppy Boy Tim Kalpakis. Oh yeah, and there's a little bit extra from your boys thrown in there to sweeten the pot. Actually I just looked and it's like 30 extra minutes. We could have just done a new episode. Oh well. Pour 'em up and enjoy the show! And when you're done, click here to say why it's total bs we didn't do 30 more measly minutes to justify an all-new ep this week: Patreon.com/yourkickstartersucksLook into the mirror, say "funny guest" three times, and what will appear? Writer and comedian Tim Kalpakis, of the Birthday Boys and Sloppy Boys, that's who! Tim pours us a couple of Bloody Marys and talks about some of our favorite topics: Bar Rescue, getting an MRI, and why Mike Mitchell is everybody's favorite. Plus, you know we had to get a former SNL writer (Lorne.) to help us punch up some JokeBlogger jokes! This is one hell of an ep, so pull up your barf bucket and get ready to laugh!Check out the Sloppy Boys podcast wherever you get your shit, and support them on Patreon for even more classic Sloppy Boys content. See acast.com/privacy for privacy and opt-out information.

Ever wonder what it's like to become a participant in a clinical research study? This podcast outlines all aspects of recruitment, vetting, protocols, and considerations for joining a study and dispels common misconceptions often fostered by Hollywood movies or TV shows. Jessica Ganga, Communications & Digital Media Coordinator at the Foundation, moderates a panel of research coordinators for mobility, spinal cord injury (SCI), stroke, and traumatic brain injury (TBI) and the Foundation's recruitment manager. They share how volunteers help Kessler Foundation further its clinical research on advancing treatments, which impact the lives of individuals with disabilities worldwide. Volunteers are the heart of our research! Learn more about the panel: Rachel Byrne, Senior Research Coordinator (SCI) https://kesslerfoundation.org/aboutus/Rachel%20Byrne Kate Goworek, Research Coordinator (Mobility) https://kesslerfoundation.org/aboutus/Kathleen%20Goworek Jenny Masmela, Senior Research Coordinator (Stroke) https://kesslerfoundation.org/aboutus/Jenny%20Masmela Sam Schmidt, Research Recruitment Manager https://kesslerfoundation.org/aboutus/Samantha%20Schmidt Angela Smith, Senior Research Coordinator (TBI) https://kesslerfoundation.org/aboutus/Angela%20Smith Frequently Asked Questions about the Foundation's Research - https://kesslerfoundation.org/research-faq Volunteers are the heart of our research! Interested in joining a study? For more information on in-person and tele-studies, go to https://kesslerfoundation.org/join-our-research-studies Definitions/Keywords ================================================= What is spatial neglect? Patients who have had a stroke or traumatic brain injury may have a neurological syndrome called spatial neglect, which affects their ability to pay attention to their surroundings and body parts on the less affected side (the left side for patients with right brain injury). Spatial neglect is disabling. Patients may 'forget' to shave, groom, or dress the left side of their bodies. They also have major problems with driving, reading, and balance. https://kesslerfoundation.org/research/stroke/rehabilitation/spatial-neglect/caregiver https://kesslerfoundation.org/research/stroke/rehabilitation/spatial-neglect/professional What is KF-NAP®? Kessler Foundation Neglect Assessment Process (KF-NAP®) is an assessment tool that may help clinicians detect the presence of spatial neglect and measure the severity of the syndrome. What is KF-PAT®? Kessler Foundation Prism Adaptation Treatment (KF-PAT®) is implemented in occupational therapy for post-stroke spatial neglect. Including prism adaptation treatment in standard of care for patients with post-stroke spatial neglect improved functional and cognitive outcomes. What is MRI contrast There are two major types of Magnetic Resonance Imaging (MRI) scans: with contrast and non-contrast. The main distinction is that for contrast MRIs, a dye (gadolinium-based) is given to the patient intravenously before the scan. Contrast is often order by a physician who wants to highlight a particular part of the body. What is HIPPA? The Health Insurance Portability and Accountability Act of 1996 (HIPAA) is a federal law that required the creation of national standards to protect sensitive patient health information from being disclosed without the patient's consent or knowledge. For more information, go to https://www.hhs.gov/hipaa/for-professionals/privacy/index.html ================================================= Tuned in to our podcast series lately? Join our listeners in 90 countries who enjoy learning about the work of Kessler Foundation. Be sure to subscribe to our SoundCloud channel “KesslerFoundation” for more research updates.

In this episode, I talk with Cathy Price, Professor of Cognitive Neuroscience and Director of the Wellcome Trust Centre for Neuroimaging at University College London, about her pioneering work on functional neuroimaging of the language network, whether there are really such things as “language regions”, degeneracy, predicting and explaining language outcomes after stroke, and more.Price C, Wise R, Ramsay S, Friston K, Howard D, Patterson K, Frackowiak R. Regional response differences within the human auditory cortex when listening to words. Neurosci Lett 1992; 146: 179-82. [doi]Price CJ, Wise RJS, Warburton EA, Moore CJ, Howard D, Patterson K, Frackowiak R, Friston K. Hearing and saying. Brain 1996; 119: 919-31. [doi]Price CJ, Friston KJ. Degeneracy and cognitive anatomy. Trends Cogn Sci 2002; 6: 416-21. [doi]Crinion J, Price CJ. Right anterior superior temporal activation predicts auditory sentence comprehension following aphasic stroke. Brain 2005; 128: 2858-71. [doi]Price CJ, Seghier ML, Leff AP. Predicting language outcome and recovery after stroke: the PLORAS system. Nat Rev Neurol 2010; 6: 202-10. [doi]Price CJ. A review and synthesis of the first 20 years of PET and fMRI studies of heard speech, spoken language and reading. NeuroImage 2012; 62: 816-47. [doi]Hope TMH, Seghier ML, Leff AP, Price CJ. Predicting outcome and recovery after stroke with lesions extracted from MRI images. NeuroImage Clin 2013; 2: 424-33. [doi]Seghier ML, Price CJ. Interpreting and utilising intersubject variability in brain function. Trends Cogn Sci 2018; 22: 517-30. [doi]Price lab websiteTranscript

Pitbulls are ok, good time sucked, the Gale movie is good, pepper spray is the best xmas gift, i did not booty bump you, lock picking is fun, cooking is awesome and i want to get better, i got in a ufc fight against my new toothbrush, i'm getting an MRI soon this will be fun. 

The last half of December marks our annual NAFLD Year-in-Review. Episodes 62-64 each include ~20 minute segments of longer interviews with Stakeholders who have made a dent in Fatty Liver disease in 2021. In this episode, Louise Campbell and Roger Green are joined by Mazen Noureddin,  Alina Allen, Wayne Eskridge.Highlights: 7:51 – Mazen Noureddin begins talking about AI and histopathology by pointing to recent review papers listeners should read, one from Mayo Clinic and another from Mazen and colleagues. 8:21 – AI tools: machine learning and deep learning. Key AI targets: non-invasive testing and histology. More recent progress in histology.10:09 – History of why histology in NASH has become increasingly controversial over time and how the challenge will grow. AI can address many of these controversies.12:42 – Paper earlier this year: three expert pathologists working in tandem can strengthen reliability AND their results correlated with PathAI. AI also provided more granularity on specific disease levels within a cirrhotic liver and reduced placebo success rate.17:10 – Louise: Should Intercept use AI methods in their re-read of 18-month biopsy data? Mazen: yes. We need a path to get regulators to accept AI this way.19:40 – Louise: Why don't we use Ishak instead of Metavir for cirrhosis coding? Mazen:  another great question!  22:01 – Alina Allen begins23:20 –  In the past year, we have learned that not only is MRE the most accurate estimator of fibrosis, but we can diagnose now based on liver stiffness (LSM) + PDFF, all in an automated 5-minute process.24:51 – Mayo CGH study (2021) proves we can correlate LSM today with five-year outcomes. Provides far better trial screening and matching data than simple biopsy. 27:07 – Roger: how can this change how we coach and advise patients?  29:04 – Alina: we can use LSMs today to inform patients better, improve their care and allocate use of expensive tests more properly.  30:55 – Roger: how does this fit into a Critical Care Pathways world. Alina: we can improve 1st-line granularity via AI analysis of patient's medical history. If this filters more people out, it makes elastography or a blood-based biomarker more efficient, therefore more affordable,.33:07 – Roger notes that sounds more like common commercial uses of AI than the AI-based histology reading we discussed with Mazen.   35:43 – Louise: if you had a magic wand, what model would you create to make MRE available when appropriate. Alina – first, teach people it is not too expensive or  difficult, then create regional centers of excellence by putting software on existing MRI machines. Finally, educate patients and physicians. 38:10 – Alina: you do not need a full 45-minute MRI to get an MRE, but only a  5-10 minute process. thereby saving time and money.41:03 – Wayne Eskridge begins42:35 – Wayne: decision to start the SUNN study borne of dissatisfaction over recommended standard NOT to screen for NAFLD. 43:35 – Study pitch received unexpectedly positive reception from industry but learning about IRBs and trial management was a “real education.” 46:12 – Wayne: point of study was to go outside medical system to asymptomatic, uninformed people, in the belief they had underlying health concerns and would tbe motivated to learn.47:48 – Louise: "Amazing" study identified potential clinical trials candidates.  Why does SUNN show far higher levels of fibrosis than the other studies?48:56 – Wayne: this is not a general population study, numbers probably are higher. 52:19 – Peak age of 40-50 is younger than with most studies; we know it progresses steadily. Message: we should be screening high-risk patients younger.55:14 – Wayne: Hard cost was ~$120. Took 8 months to complete running heavy patient loads.

An interview with Dr. Megan Daly from University of California in Davis, California and Dr. Navneet Singh from the Postgraduate Institute of Medical Education & Research in Chandigarh, India, co-chairs on “Management of Stage III Non–Small-Cell Lung Cancer: ASCO Guideline.” They summarize guideline recommendations on five subtopics – evaluation & staging, surgery, neoadjuvant therapy, adjuvant therapy, and unresectable disease. Read the full guideline at www.asco.org/thoracic-cancer-guidelines.   TRANSCRIPT [MUSIC PLAYING]   ANNOUNCER: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. BRITTANY HARVEY: Hello, and welcome to the ASCO Guidelines podcast series, brought to you by the ASCO Podcast Network, a collection of nine programs covering a range of educational and scientific content and offering enriching insight into the world of cancer care. You can find all the shows, including this one, at ASCO.org/podcasts. My name is Brittany Harvey, and today, I'm interviewing Dr. Megan Daley from University of California in Davis, California, and Dr. Navneet Singh from the Post-Graduate Institute of Medical Education and Research in Chandigarh, India, co-chairs on management of stage III non-small cell lung cancer ASCO guideline. Thank you for being here, Dr. Daley and Dr. Singh. MEGAN DALEY: Thank you for having us. NAVNEET SINGH: Thank you for having us, too. BRITTANY HARVEY: First, I'd like to note that ASCO takes great care in the development of its guidelines and ensuring that the ASCO conflict of interest policy is followed for each guideline. The full conflict of interest information for this guideline panel is available online with the publication of the guideline in the Journal of Clinical Oncology. Dr. Daley, do you have any relevant disclosures that are directly related to this guideline topic? MEGAN DALEY: I have research funding from EMD Serono, Merck, and Genentech. BRITTANY HARVEY: Thank you for those disclosures. Then Dr. Singh, do you have any relevant disclosures that are directly related to this guideline? NAVNEET SINGH: No, I have no financial conflicts of interest. BRITTANY HARVEY: Thank you. Getting into the content of this guideline, Dr. Singh, can you give us an overview of both the scope and the purpose of this guideline? NAVNEET SINGH: Yes, absolutely. So this guideline has been developed to assist clinicians involved in the management of patients with stage III non-small-cell lung cancer, or NSCLC, as we call it briefly. Now, stage III NSCLC represents one of the most heterogeneous subgroups of lung cancer. Consequently, it is also the subgroup in which the choice of multimodality treatment and the sequence of multimodality treatment varies significantly amongst clinicians, with variations being observed across institutes, as well as within an institute. And we sincerely hope that, with the help of this guideline, clinicians can accurately confirm the presence of stage III disease and offer the most appropriate treatment based on clinical and radiographic characteristics, as well as other medical factors that influence treatment decision-making. This evidence-based guidance also seeks to provide clarification on the common clinical dilemmas that clinicians may have while evaluating a patient with suspected or known stage III NSCLC. BRITTANY HARVEY: Thank you for that background information, Dr. Singh. Then, Dr. Daley, this guideline addresses five main sections, evaluation and staging, surgery, neoadjuvant therapy, adjuvant therapy, and unresectable disease. So starting with evaluation and staging, what are the key recommendations for workup for patients with suspected stage III non-small cell lung cancer? MEGAN DALEY: Our first recommendation for such patients is that they should undergo a history and physical exam and a CT scan of the chest and upper abdomen with contrast, unless it's contraindicated. If metastatic disease is not identified on CT, those patients should go on to a PET CT scan and MRI of the brain. If the patients are being considered for curative intent treatment, the guideline recommends pathologic mediastinal lymph node assessment. And we recommend that endoscopic techniques should be offered as the initial staging modality, if available. If not available, invasive surgical mediastinal staging should be offered. And finally, for patients who have suspected or confirmed stage III lung cancer, we recommend that multidisciplinary discussion should occur prior to any initiation of a treatment plan. BRITTANY HARVEY: Great, I appreciate your reviewing those recommendations. So following that, Dr. Singh, what does the guideline recommend regarding which patients with stage III non-small-cell lung cancer should be considered for surgical resection? NAVNEET SINGH: So in this guideline, the recommendation which has come forth is that for patients with stage IIIA, basically N2 disease, induction therapy should be followed by surgery with or without adjuvant therapy if several conditions are met. Basically, a complete resection of the primary tumor and the involved lymph nodes is deemed feasible, and three nodes or contralateral lymph nodes are deemed to be not involved, and the expected perioperative 90-day mortality is low, typically 5% or less. Another recommendation is that for selected patients with the P4N0 disease, surgical resection may be offered if medically and surgically feasible following multidisciplinary review. We would like to emphasize here that surgeons should always be involved in decisions regarding the feasibility of surgical resection. And they are an integral part of a multidisciplinary evaluation for surgical resection for stage III NSCLC patients. BRITTANY HARVEY: Great. Then Dr. Singh just reviewed who should be considered for surgical resection. So Dr. Daley, for patients with potentially resectable stage III non-small-cell lung cancer, what are the key recommendations for neoadjuvant therapy? MEGAN DALEY: Our first recommendation is that patients who are planned for a multimodality approach that will incorporate surgery should receive systemic neoadjuvant therapy. Second, that those patients with N2 disease who are planned for surgical resection should receive either neoadjuvant chemotherapy or neoadjuvant concurrent chemoradiation. And finally, for patients with a resectable superior sulcus tumor, neoadjuvant concurrent chemoradiation should be administered. BRITTANY HARVEY: Understood. Then in addition, Dr. Singh, for patients with resected stage III non-small-cell lung cancer, what are the key recommendations for adjuvant therapy? NAVNEET SINGH: So the panel came up with three recommendations for adjuvant treatment. The first is that patients with resected stage III NSCLC who did not receive neoadjuvant systemic therapy should be offered adjuvant platinum-based chemotherapy. The second recommendation which we came up was that for patients with resected stage III disease and presence of a sensitizing EGFR mutation-- classically, exon 19 deletion or the L858R exon 21 point mutation-- they may be offered adjuvant osimertinib, which is an EGFR inhibitor, after platinum-based chemotherapy. And this is based upon the ADAURA trial, which was published last year. And the third recommendation was that for patients with completely resected NSCLC and mediastinal involvement N2 disease, but without extracapsular extension, post-operative radiotherapy should not be routinely offered. BRITTANY HARVEY: OK. And then the last section of recommendations covers unresectable disease. So Dr. Daley, what does the guideline recommend regarding the management of unresectable stage III non-small-cell lung cancer? MEGAN DALEY: The guideline first recommends that these patients who have a good performance status should be offered concurrent, rather than sequential, chemoradiation, that concurrent chemotherapy delivered with radiation should include a platinum-based doublet, preferably cisplatin-etoposide, carboplatin-paclitaxel, or cisplatin-pemetrexed or cisplatin-vinorelbine. The patients who are not candidates for concurrent chemoradiation, but who are potentially candidates for chemotherapy, should be offered sequential chemoradiation, rather than radiation alone, that patients receiving concurrent chemoradiation should be treated to 60 gray. And that's based on the results of RTOG 0617. We also recommend within the guideline that doses higher than 60 gray and up to 70 gray could be considered for selected patients, with careful attention to doses to the heart, lung, and esophagus, among other organs. The guideline also recommends that patients receiving definitive radiation without chemotherapy, that hypofractionation using slightly larger doses could be considered-- over 2 gray per fraction, and up to 4 gray per fraction, and that patients without disease progression during concurrent chemoradiation should be offered consolidation durvalumab, based on the PACIFIC trial. BRITTANY HARVEY: Thank you both, then, for reviewing the key recommendations of this guideline. So, Dr. Singh, in your view, what is the importance of this guideline, and how does it impact clinicians? NAVNEET SINGH: I think this guideline will go a long way in helping clinicians who are involved in the diagnosis and treatment of lung cancer, especially stage III NSCLC. As mentioned earlier, this is a very heterogeneous disease. And there are several challenging situations, both in the context of diagnosis, as well as treatment. And using this guideline, which has an extensive evidence review, as well as the development of two very helpful algorithms, we sincerely hope that clinicians who are both in academic centers as well as in practice in the community are able to accurately diagnose stage III, appropriately stage it, and offer the best treatment, given the patient characteristics and the disease characteristics and available resources. BRITTANY HARVEY: Great. Those are important points. So then, finally, Dr. Daley, how will these guideline recommendations affect patients? MEGAN DALEY: Well, we hope very much that these guidelines will help patients consistently receive high-quality care for their stage III lung cancer. In particular, we're hoping that the recommendation from multidisciplinary assessment of patients prior to treatment is carefully followed. We're hoping that some of the recommendations surrounding the appropriate workup for patients may help ensure that all patients receive a thorough and complete workup prior to initiation of treatment. And the guideline, in particular, is highlighting some of the more recent developments in stage III lung cancer, such as the use of consolidation durvalumab based on the PACIFIC trial, the use of osimertinib in resectable disease based on the ADAURA trial. And we're hoping to make sure that these results are disseminated to practitioners everywhere so that patients can receive the latest and best care for their stage III lung cancer. BRITTANY HARVEY: Understood. Yeah, as you both mentioned, we hope that this has a positive impact for both clinicians and patients. So I want to thank you both for all of your hard work to develop this guideline and the evidence-based recommendations along with it. And thank you for taking the time to speak with me today, Dr. Daley and Dr. Singh. MEGAN DALEY: Thank you so much for having us. NAVNEET SINGH: Thank you. BRITTANY HARVEY: And thank you to all of our listeners for tuning into the ASCO Guidelines podcast series. To read the full guideline, go to www.asco.org/thoracic-cancer-guidelines. You can also find many of our guidelines and interactive resources in the free ASCO guidelines app, available in iTunes or the Google Play store. If you have enjoyed what you've heard today, please rate and review the podcast, and be sure to subscribe so you never miss an episode. [MUSIC PLAYING]

This episode is a discussion about how we deal with regression and celebrate progress. We also talk about the continuous pursuit of medical assistance for Bryce's brain and his gut. It's never ending but takes on different forms for Bryce. We are making adjustments for supplements as we monitor bloodwork and behaviors. We also got established with a new neurologist and will begin EEG and MRI testing next month. We talk about the benefits we have noticed when we travel with Bryce along with how we are enjoying this Christmas season with Bryce. His language and vocabulary continue to expand which has been very encouraging with the additional steps we have taken the past four months while working with the functional medicine doctor. Bryce is a funny, mechanical, HAPPY little guy who was diagnosed with autism at age two and is now eight years old. His pure joy makes this world a much better place!If you are enjoying the show, please take a quick moment to give us a rating and review to help other families find our podcast, too. We are humbled and honored to follow our calling and be Autism Ambassadors while helping others understand our world a little more than they did before listening to the podcast. We also feel called to bring light to a community that has experienced dark days after the "diagnosis". (Luke 1:79) You can follow us on our Facebook and Instagram pages, Parenting Autism, to see stories, pictures, and videos of our autism journey. www.ParentingAutismShow.comYou can also contact us through Facebook, Instagram, or our email: parentingautism@att.net.We are also linking our podcast to our photography website to help create more awareness. www.artigraphsphotography.comSupport the show (https://www.parentingautismshow.com/resources)Support the show (https://www.parentingautismshow.com/resources)

I am happy to share my new book THE KNEE BOOK - A GUIDE TO THE AGING KNEEIt was written for patients and it is written to patients in easy to understand language.The book is a perfect recommendation for patients with knee pain that have questions.I believe it is also a great resource for residents and young surgeons. In it I review the algorithm for treating patients with knee pain from the most conservative up to knee replacement.What I think is the best benefit for young surgeons is all of the analogies I use to explain things to my patients. You can pick these up by reading the book so that you can better explain things to your patients.It is also a great read for non-orthopedic doctors, PA's or NP's. Anyone that treats knee pain patients. It explains why we need weight bearing x-rays and not MRI's and more.You can download the ebook at Amazon here:https://www.amazon.com/Knee-Book-Guide-Aging-ebook/dp/B09NLL58LG/ref=tmm_kin_swatch_0?_encoding=UTF8&qid=1639946441&sr=8-2You can get the paperback here:https://www.amazon.com/Knee-Book-Guide-Aging/dp/B09NKWMYFN/ref=tmm_pap_swatch_0?_encoding=UTF8&qid=1639946441&sr=8-2Available at Barnes and Noble as a Nook here:https://www.barnesandnoble.com/w/the-knee-book-a-guide-to-the-aging-knee-adam-rosen/1140795276?ean=2940161052846 Support the show (https://www.patreon/TotalKneeTips)

Alguna vez viste el Programa de MR ROGERS?Una al día... una aventura de 365 días. Nos escuchamos mañana.®Derechos Reservados por contenido original de Susana Godoy.Ingeniera,Terapeuta infantil, Familiar y de Pareja. CEFAP, MRI.www.susanagodoy.comFacebook: https://www.facebook.com/SusanaGodoyL/Instagram: https://www.instagram.com/susy_godoy_l/YouTube: https://www.youtube.com/c/SusanaGodoyLSupport the show (https://www.paypal.com/donate?hosted_button_id=RN2LDABK7VH6W)

Los Arqueros practican diariamente, se concentran, apuntan y disparan... les ha llevado mucha practica dar en el centro de la Diana.Una al día... una aventura de 365 días. Nos escuchamos mañana.®Derechos Reservados por contenido original de Susana Godoy.Ingeniera,Terapeuta infantil, Familiar y de Pareja. CEFAP, MRI.www.susanagodoy.comFacebook: https://www.facebook.com/SusanaGodoyL/Instagram: https://www.instagram.com/susy_godoy_l/YouTube: https://www.youtube.com/c/SusanaGodoyLSupport the show (https://www.paypal.com/donate?hosted_button_id=RN2LDABK7VH6W)

Para estar presente es necesario muchas veces.... sólo eso... Estar. Estar presente....Una al día... una aventura de 365 días. Nos escuchamos mañana.®Derechos Reservados por contenido original de Susana Godoy.Ingeniera,Terapeuta infantil, Familiar y de Pareja. CEFAP, MRI.www.susanagodoy.comFacebook: https://www.facebook.com/SusanaGodoyL/Instagram: https://www.instagram.com/susy_godoy_l/YouTube: https://www.youtube.com/c/SusanaGodoyLSupport the show (https://www.paypal.com/donate?hosted_button_id=RN2LDABK7VH6W)

Assuming you've recently ordered the expanded labs that we suggested on page one of the Blood Work Cheat Sheet, here's a additional assessments to consider to see if your lifestyle is maximizing your health. Save on your Omega-3 Index Test by MYOXCIENCE Nutrition Use code Podcast at checkout Enroll in the Blood Work MasterClass   Time Stamps 00:25 Measuring your omega 3 index is more important for men and post-menopausal women. Hormone changes in post-menopausal women greatly increases risk of heart disease. 0:44 Bill Harris, PhD explains the omega-3 index 2:23 An omega 3 index below 4%, reflects higher risk of sudden cardiac death, having a fatal heart attack, should they have a heart attack. 03:40 Omega 3s in the 6% to 8% range is optimal for reducing risk of sudden cardiac death, compared to those of us with omega 3 index of 3 or 4%. 04:00 OmegaQuant offers an at home test of your Omega 3s. The OmegaQuant test quantifies the percentage of EPA and DHA in your red blood cell membranes. They also look at palmitate. 04:15 When palmitate increases, it is a proxy that potentially de novo lipogenesis is occurring. This means that insulin is causing your liver to increase fatty acid synthesis, which can result in insulin resistance and fat gain. 05:15 A DEXA scan will show you where your fat is being distributed. It will also give insights into your bone mineral density. Ageing and gaining fat around the middle, has been linked with low mineral density and muscle mass. 05:23 Osteosarcopenic obesity is the simultaneous loss of bone mineral density, loss of muscle and gain of fat. 03:50 A DEXA scan every 2 years tracks the trajectory of your body composition and your muscle. The amount of fat on your body is a reflection of your vitality. 05:25 A full body MRI every 5 years or so can be done if you have cancer in your close family or you are a former smoker. 06:42 If cardiovascular disease runs in your family, or you have sleep apnea, iron overload or insulin resistance, you may consider testing your CIMT (carotid intimal thickness). It shows how much atherosclerosis or stenosis is in the carotid arteries. A coronary artery calcium score is more invasive. 07:30 The arterial pulse wave velocity test is non-invasive. It measures the elasticity of your vessels. Stiff arteries are characteristic of inflammation.

Watch on YouTube --> FDA's Role in the Off Label UseIn this episode of Zone 3 Podcast, we are lucky to have returning guest Emanuel Kanal, MD, FACR, FISMRM, MRMD, MRSE, AANG. Chief, Division of Emergency Radiology and Teleradiology. Director, Magnetic Resonance Services. Professor of Radiology and Neuroradiology. Department of Radiology University of Pittsburgh Medical Center,  here to discuss the FDA's role.Specifically, how the FDA only governs who can market in the US, not how MD should practice medicine.He also discusses how off-label use should be the standard if that is what is best for the patient regardless of FDA approval. Dr. Kanal helps to explain this by discussing an example about the neonate formula. He urges viewers to understand FDA's approval regarding MRI safety is only to those companies who find it beneficial(profitable) to get FDA approval.  He also talks about the FDA approval process and how the safety guidelines are created. He takes us through many dates on how the FDA came to be, reminding us of the big picture of the FDA's role as a federal regulator. Toward the end, Dr. Kanal discusses his passion for flying. As a licensed pilot, Dr. Kanal tries to find the time in his busy schedule. It was fun to sit down with Dr. Kanal and see and hear that passion when spoke to him about something other than Diagnostic imaging. Thanks for Joining Us here in Zone 3. Timestamps below00:00 intro00:54 Dr. Kanal Intro26:47 FDA's Role and Why they don't have oversight over how MD practice Medicine51:00 -Liability when going off Label  1:20:45 Message to Technologist1:28:51 Community Questions1:50:19 Outro with Sponsor  popupAbout our Sponsor:  Aegys is an innovative leader in the MRI safety industry and the Creator of The TechGate Automatic.Aegys is committed to providing innovative product and process solutions that enhance overall magnet safety and improve efficiency.  TechGate Auto is a Zone 4 Barrier System that keeps patients and MRI technologists safe.  TechGate Auto allows technologists to focus on the care of patients and efficient room turnaround rather than worrying about anyone entering the MRI room behind them. Easy to use and designed for the MRI environment, TechGate Auto is deployed whenever the technologist enters or leaves the MR room or via push-button remote control, providing an immediate physical restriction of access to all unauthorized individuals.The use of a “caution” barrier at the entrance to the MR room is now a recommendation of the American College of Radiology MR Safety Committee.Links Aegys' Tech Gate Auto-  https://aegysgroup.com/Questions Link- https://community.imagingqa.com/

Thanks for tuning in to the Armor Men's Health Hour Podcast today, where we bring you the latest and greatest in urology care and the best urology humor out there.In this segment, Dr. Mistry and Donna Lee answer a listener question about semen. Our listener asks, "Upon discharge, I noticed my semen color is greenish gray for the last 10 months, approximately. Do I need to be worried? My last blood work showed up that all is well with my blood. Not eating anything different from before, and then this started happening." This is a great question, and one Dr. Mistry hears often from his patients. While many people assume that semen is the main component of ejaculate, it is actually composed of material from the prostate gland. Ejaculate stored in the seminal vesicles exits through the urethra, and in the course of this journey out of the body, color change can occur for a variety of reasons. Most often, discolored ejaculate is a sign of prostate infection. It is very rarely associated with fertility. Red ejaculate is generally from blood in the sperm, also called hematospermia, and this is usually caused by prostate infection. If you ejaculate and your sperm is red, then don't ejaculate again for a while, it may be a darker red or brown at that time. Any discolored ejaculate must be discharged before normalcy can return. A greenish discharge may be associated with venereal infections like chlamydia or gonorrhea, but not in every case. In addition, smelly ejaculate can signify an infection, and should be evaluated by a urologist. Usually a semen culture can help identify the cause. In other situations, placing a tiny camera in the bladder to rule out other causes of infection may be necessary. If the ejaculate is highly suspicious, a PSA and an MRI of the pelvis and seminal vesicles is usually helpful in ruling out serious illness. If you or someone you love is concerned about the appearance or quality of their ejaculate, please give us a call today!This episode previously aired on 11.6.21. Don't forget to like, subscribe, and share us with a friend! As always, be well!Check our our award winning podcast!https://blog.feedspot.com/sex_therapy_podcasts/https://blog.feedspot.com/mens_health_podcasts/Dr. Mistry is a board-certified urologist and has been treating patients in the Austin and Greater Williamson County area since he started his private practice in 2007.We enjoy hearing from you! Email us at armormenshealth@gmail.com and we'll answer your question in an upcoming episode!Phone: (512) 238-0762Email: Armormenshealth@gmail.comWebsite: Armormenshealth.comOur Locations:Round Rock Office970 Hester's Crossing Road Suite 101 Round Rock, TX 78681South Austin Office6501 South Congress Suite 1-103 Austin, TX 78745Lakeline Office12505 Hymeadow Drive Suite 2C Austin, TX 78750Dripping Springs Office170 Benney Lane Suite 202 Dripping Springs, TX 78620

Even without MRI evidence, psychosomatic syndromes are very real and can be devastating. Neurologist Suzanne O'Sullivan joins host Krys Boyd to discuss her travels around the world trying to understand seemingly odd or fantastical illnesses that spread in communities, and the very real humans who suffer from them. Her book is called “The Sleeping Beauties: And Other Stories of Mystery Illness.”

Episode 78: Infantile Hemangioma. Dr Shelat discusses with Dr Schlaerth and Dr Arreaza the definition, pathophysiology, diagnosis and treatment of infantile hemangioma.___________________________Infantile Hemangioma. By Tejal Shelat, MD (Lady Hardinge Medical College). Discussed with Katherine Schlaerth, MD; and Hector Arreaza, MD.   This is Rio Bravo qWeek, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California. Our program is affiliated with UCLA, and it's sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. What is infantile hemangioma?Infantile hemangioma is vascular overgrowth that leads to tangled blood vessels that appear as a reddish plaque on the skin as early as days to weeks after birth.  It is the most common benign vascular tumor in infants, with a prevalence of 4-5% in mature neonates and is about 2.5 times more common in female (ratio female:male is 3:1) and Caucasian children.  Risk factors: There are several risk factors, including prematurity, low birth weight less than 1000g, family history of infantile hemangioma, placental anomalies, and eclampsia. Progression of infantile hemangioma. Hemangiomas typically undergo three phases:First is the proliferation phase that occurs between 0 to 6 months of age, with about 80% growing to their final size by age 3 months. During this time there is growth of a bright red, soft, raised, non-blanching plaque that is visible on the skin. This occurs to due proliferation of rapidly dividing endothelial cells in the blood vessels.This is followed by a plateau phase.Next is the involution phase, that occurs after 6 months of age. The lesion/s now turn deep red or violet and spontaneously begin to regress in size. Pathogenesis. Several hypotheses have been described to explain the reason behind the occurrence of hemangiomas. We now know that they occur due to dysregulation in angiogenesis and vasculogenesis.  The most likely trigger is thought to be hypoxia, which induces transcription of the Vascular Endothelial Growth Factor (VEGF) gene, leading to overexpression of angiogenic factors such as VEGF. This leads to differentiation of endothelial cells, influx of other cells such as mast cells, myeloid cells and also tissue inhibitors of metalloproteinases (TIMPs). Regression.  The mast cells produce interferon and transforming growth factor, which, along with the TIMPs that we just talked about all work together to halt the proliferation of endothelial cells. The endothelial cells then become senescent and that leads to passive involution of the hemangioma. Diagnosis. The diagnosis of infantile hemangiomas is clinical. If you are not familiar with how a hemangioma looks, search in your favorite dermatology atlas.  A hemangioma may be red if it involves the papillary dermis (called superficial strawberry hemangiomas), but they can also be purple, blue, or colorless if they involve the reticular dermis or subcutaneous fat (called deep, cavernous hemangiomas). Early white discoloration of infantile hemangioma may be an early sign of imminent ulceration. Additional workup.  Further investigation is also required in specific situations: If there are 5 or more cutaneous lesions, we would need a liver ultrasound to rule out involvement of the liverFor facial or segmental involvement, echocardiogram and MRI of the head are recommended to rule out posterior fossa malformations, hemangioma (usually localized on the face), arterial anomalies, cardiovascular anomalies, eye anomalies, sternal clefting and/or supraumbilical raphe  PHACE Syndrome: posterior fossa brain malformations, hemangiomas, arterial anomalies, coarctation of the aorta and cardiac defects, and eye abnormalities. By definition, PHACE is diagnosed when there is at least one hemangioma >5 cm on head/scalp PLUS one major or two minor criteria OR hemangioma of any size on neck, upper trunk and proximal upper extremity plus two major criteria.Major criteria include arterial anomalies such as anomaly of major cerebral or cervical arteries, retinal vascular anomalies, sternal defect. Minor criteria include cerebral artery aneurysm, ventricular septal defect, etc. Laryngoscopy should be done if there is cervicofacial involvement, i.e., beard distribution Spinal ultrasound should be performed if the hemangioma is in the lumbosacral region Management-Most hemangiomas will not require treatment, and most need observation only. -When treatment is needed, treatment is usually medical depending on severity, location, and extension of hemangioma/s, you may decide to go with topical or systemic therapy.-Topical therapies include beta blockers (propranolol 1% applied TID for 1 year), corticosteroids, and imiquimod, but data on efficacy is limited.-Systemic therapies: Beta blocker therapy (with propranolol by mouth) is indicated when there is concern for ulceration or scarring in large, facial, segmental and or rapidly growing hemangiomas, for visual impairment in periorbital involvement, high output heart failure in hepatic involvement and airway obstruction in subglottic involvement. The dose of propranolol is 1mg/kg to 3mg/kg in the form of an oral solution, depending on the response to therapy and weight of the child. Initiation of therapy may require hospital admission to watch for side effects to beta blockers.-Second-line treatments include systemic corticosteroids-Surgical intervention is rarely needed, and it´s usually avoided because surgical scars may be worse than the resulting lesion after spontaneous regression.  Prognosis. The prognosis is very good for most uncomplicated hemangiomas, with about 50% undergoing complete involution by age 5 years and about 90% by age 9 years. Permanent cutaneous residua are seen for hemangiomas that involute slowly, after 6 years of age and hemangiomas involving the eyelid, nasal tip, ear and lip. Functional impairment or obstruction may occur when the hemangioma is located near natural orifices and/or in the head and neck area. In these cases, surgical intervention may be needed. Conclusion. You may find hemangiomas during routine physical exam of a newborn. It is important to remember the natural progression of uncomplicated hemangiomas. Make sure to educate parents about concerning features and how to determine if treatment is needed. In most cases, when treatment is needed, a dermatology evaluation is needed. ___________________________ [Music to end: JERUSALEMA]Now we conclude our episode number 78 “Infantile Hemangioma.” We learned about the natural progression of most hemangiomas. They grow for up to 3 years, then remain unchanged until around 6 years of age when they gradually regress without treatment. In most cases, monitoring is all what's needed. However, it's important to identify the hemangiomas with concerning features that require additional work up or early treatment. Treatment is mainly medical. Surgery is rarely recommended or required. Even without trying, every night you go to bed being a little wiser.Thanks for listening to Rio Bravo qWeek. If you have any feedback about this podcast, contact us by email RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. This podcast was created with educational purposes only. Visit your primary care physician for additional medical advice. This week we thank Hector Arreaza, Tejal Shelat. Audio edition: Suraj Amrutia. See you next week! _____________________References:Léauté-Labrèze, C., Harper, J. I., & Hoeger, P. H. (2017). Infantile haemangioma. The Lancet, 390(10089), 85-94.Kowalska, M., Dębek, W., & Matuszczak, E. (2021). Infantile Hemangiomas: An Update on Pathogenesis and Treatment. Journal of clinical medicine, 10(20), 4631.Metry D.W. Infantile hemangiomas: Epidemiology, pathogenesis, clinical features, and complications. UpToDate. Accessed December 5, 2021. https://www.uptodate.com/contents/infantile-hemangiomas-epidemiology-pathogenesis-clinical-features-and-complications#H22.Antaya R.J. Infantile Hemangioma. Medscape. Accessed December 5, 2021. https://emedicine.medscape.com/article/1083849-overview#a1.

Dear Johnny – I've never really had to ask for help until now. My name is Russell and I'm 55 years old. I hit a rough patch last year on October 21, 2020, I was diagnosed with stage 4 colon cancer which has moved to my liver, lungs and near my brain stem. I was having headaches at work and went to the doctor for an MRI. They took the two tumors off my brain stem and then discovered it had moved to other places in my body. I can no longer work and I'm on disability. My wife has been by my side running me back and forth from chemo treatments to doctors to physical therapy. She does everything for me and is still holding down a 40 hour per week job. I'm not sure how she does it, but she does. She has had to take time off here and there to keep me going and sometimes we struggle to keep up on bills. We've been together for 27 years and she's done so much for me and I just want to give her a break and show her how much she means to me. Thank you for taking time to read my letter and anything you could do, would be greatly appreciated. – Russell Who Helped: Heather, Richard & Dana, Jason, Jim, Chris, Dennis & crew, Consentino's How You Helped: 2 months rent, paid gas, elec. & water bills, spa day for Russell's wife and groceries! See omnystudio.com/listener for privacy information.

An MRI can be very helpful when you have a strange injury that doesn't seem to fit in any of the common running injury boxes.  I just had a call from a runner in that very situation. He is someone who has an injury and has something kind of strange going on.  He actually had an abnormal finding on an MRI from a little more than three years ago.  At the time that he had that previous MRI that thing that was a little weird on his MRI wasn't really causing a problem, but now his pain is in exactly that same spot. Today on the Doc on the Run podcast, we're talking about why runners should always get the second MRI at the same imaging facility.

When people think about multiple sclerosis, they don't often think about the eye, but vision problems are often the first signs of MS. The disease is caused by an aberrant immune response that attacks the central nervous system, which includes the brain, the spinal cord, and the optic nerve. And the optic nerve is where MS often reveals itself. Dr. Barbara Giesser specializes in the treatment of MS patients. She turns to her colleague, neuro-ophthalmologist Dr. Howard Krauss, for confirmation of early suspected MS diagnosis. Using a powerful imaging technology called optical coherence tomography, Krauss can see changes in the optic nerve long before an MRI scan would pick up evidence of MS in nerves elsewhere in the body. Monitoring the optic nerve after a diagnosis gives valuable clues as to whether MS treatments are working. Listen to this discussion to learn more about how this unlikely partnership is changing lives, and how, when it comes to MS, the eye truly is a window onto the body. For more information please visit our website: https://www.pacificneuroscienceinstitute.org/

Dear Johnny – My name is Meaghan and I've been praying for a way to be able to make this a great Christmas.   My youngest son, Grant (11), has Down Syndrome. Earlier this year he began to have accidents at school (wetting his pants) and something didn't seem right. I took him to see a specialist at Children's Mercy and after an MRI they found out he had a tethered spinal cord. With Medicaid and our stimulus check he had his first surgery in June of this year. After the surgery he began to have a stiff neck and after more appointments and an x-ray we found his neck was dislocated and he needed a spinal fusion for his C1 and C2. Post-surgery he had to wear C-collar neck brace and he just got out of his neck brace 2-3 weeks ago. I expected the first surgery, but with the second surgery I missed so much time at work that I had to leave my job in home healthcare. We are waiting to see if he is going to have to do physical therapy. The doctors want to see how he reacts without the collar. I started a new job in a dental office in October, but the time off has put me behind. I'm late on my electric and gas bills, but worry that I won't have much of a Christmas for Grant and he's been through so much this year. I have two older kids who help as much as they can, but I'm a single mom who's just trying to make ends meet. Thank you for taking the time to read my letter and Happy Holidays to all of you. - Meaghan Who Helped: Laura, Colleen, Brian, Ryan, David Ball, Shane, Angie, Danny, Adrian, Consentino's How You Helped: 2 months rent, paid electric & gas bills, Christmas for Grant and groceries! See omnystudio.com/listener for privacy information.

I was just on a second opinion telemedicine call with an injured runner. She had a recurring injury that was still keeping her from running.  Unfortunately, that injury first started eight years ago.  When you have an injury, and you get x-rays, an MRI or a CT scan, or any kind of medical imaging study that shows more detail than the x-rays, you should always get a copy of that disc.   This runner's story is a great example of why you need those images. Today on the Doc On The Run podcast we're talking about why runners should always get copies of the x-ray or MRI imaging disk.

Today's question comes from a telemedicine visit second opinion for a runner.  She was asking if she should have surgery to remove bone fragments. I said, "Well, let's talk about what's going on with you first."  Anytime we see something abnormal on an x-ray or an MRI, we often think that it's pathologic. We presume something is wrong, just because it doesn't look right.  We think if something's wrong, we should go cut your foot open and fix it. Should a runner have surgery to remove bone fragments? Well, that's a great question and that's what we're talking about today on the Doc On The Run podcast.

Videos https://brandnewtube.com/watch/sonia-elijah-interviews-efrat-fenigson-from-israel_Ws1DDYkiqAOXdis.html     https://www.youtube.com/watch?v=GWN2PV4v0lk&t=8s   Researchers find new link between a disrupted body clock and inflammatory diseases RCSI University of Medicine and Health Sciences, November 25, 2021 New research from RCSI has demonstrated the significant role that an irregular body clock plays in driving inflammation in the body's immune cells, with implications for the most serious and prevalent diseases in humans. The circadian body clock generates 24-hour rhythms that keep humans healthy and in time with the day/night cycle. This includes regulating the rhythm of the body's own (innate) immune cells called macrophages. When these cell rhythms are disrupted (due to things like erratic eating/sleeping patterns or shift work), the cells produce molecules which drive inflammation. This can lead to chronic inflammatory diseases such as heart disease, obesity, arthritis, diabetes and cancer, and also impact our ability to fight infection. (NEXT) Social media tied to higher risk of depression Massachusetts General Hospital, November 23, 2021 The latest in a spate of studies investigating links between use of social media and depression suggests the two go hand in hand. The new study follows a yearlong look at social media use and onset of depression among nearly 5,400 adults. None reported even mild depression at the start. But in multiple surveys over 12 months, depression status had worsened in some respondents, the study found. The risk rose with use of three hugely popular social media sites: Snapchat, Facebook and TikTok. None showed any signs of depression at the first survey. But after completing at least one similar follow-up, nearly 9% showed a "significant" increase in scores for depression risk. (NEXT) Havacado or two. Study finds eating lots of the fruit has public health import Randomized controlled trial found that families with high avocado consumption self-reported reduced caloric intake and an overall healthier diet University of California at San Diego, November 29, 2021 In a novel study, researchers conducted a randomized controlled trial comparing the potential health effects between families that consumed a low allotment of avocados (three per week) and families that consumed a high allotment (14 per week) over six months. They found that the high avocado allotment families self-reported lower caloric consumption, reducing their intake of other foods, including dairy, meats and refined grains and their associated negative nutrients, such as saturated fat and sodium. (NEXT) Crabapple supplements could help cut cholesterol, China study discovers Crabapple extract has been show to lower cholesterol in obese mice which were fed a high-fat diet, researchers in China have revealed. Beijing and Shanghai universities, November 30, 2021 The study points out that statins are the major therapy for hypercholesterolaemia and for the prevention of atherosclerosis. However, there is some evidence to suggest that they may increase the risk of diabetes, muscle pain, liver damage and cause other side effects. Crabapple has long been used for the treatment of diarrhoea, indigestion and other digestive diseases in traditional Chinese medicine, and its antioxidant benefits have frequently been studied. (NEXT) Aerobic exercise preserves brain volume and improves cognitive function Wake Forest School of Medicine, November 30, 2021 Using a new MRI technique, researchers found that adults with mild cognitive impairment (MCI) who exercised four times a week over a six-month period experienced an increase in brain volume in specific, or local, areas of the brain, but adults who participated in aerobic exercise experienced greater gains than those who just stretched. (NEXT) Are you a morning or an evening person? It might be due to your gut bacteria University of Haifa (Israel), November 22, 2021 A new study by the University of Haifa reveals that certain gut bacteria differ between morning and evening people. It is already known that there are some genetic differences between larks and owls, but research in fruit flies in our laboratory inspired us to test the impact of gut bacteria on human chronotypes," says Prof. Eran Tauber. Fecal samples were collected from 91 individuals in order to extract and sequence the bacterial DNA. Analysis of the DNA sequences from each sample allowed identification of all gut bacterial species and quantify their abundance. The chronotype of the participants was determined based on their self-reported sleep times during the weekend (waking up without an alarm clock). (OTHER NEXT) Sonia Elijah interviews Efrat Fenigson from Israel Efrat Fenigson, a chief marketing officer and human rights activist from Tel Aviv, Israel, candidly speaks to Sonia about how 'Covid' has been marketed, as if it were a brand, by world governments and the mainstream media. She talks about the general protest movement in Israel and how it evolved from anti-corruption to anti-lockdown/green-pass demonstrations. She gives insight into the psychological state of fear that many Israelis are accustomed to living under making them compliant in obeying the draconian Covid rules and to not question the mass vaccine rollout. (NEXT) Foreclosure Looms for Homeowners Who Thought They'd Won, Thanks to Top New York Court Ruling Sam Mellings The City and New York Focus, November 30, 2021 Christine Fife was “speechless with joy” when she won her foreclosure case in January 2020, she recalled, believing her decade under threat of foreclosure in her Upper West Side condo was finally over. Now, though, Fife is once again facing the seizure of the apartment she has owned since 1990. In February 2021, New York's top court issued a decision that eliminated a path that New York homeowners had used for years to fight foreclosure. The decision in Freedom Mortgage Corporation v. Engel allowed Fife's lender to renew its foreclosure suit against her. “They said it was OK. How can they change their mind?” Fife asked during an interview with New York Focus and THE CITY. Across New York State, homeowners who believed that their cases had been settled in their favor are now once again facing foreclosure due to the Engel decision. Many are in danger of losing their homes, even as two bills aimed at protecting owners wend their way through the state Legislature. Case Reopened In New York, if a borrower misses a mortgage payment, the lender is allowed to demand the entire remaining balance immediately and then move to foreclose after 120 days, if the money owed remains unpaid.. But a lender must start the legal proceedings within six years of first demanding full payment, or the suit becomes invalid. Until recently, the clock kept ticking until the lender informed the borrower that they were no longer seeking foreclosure. In Fife's case, the lender had never done so. The bank sued Fife twice: first in 2010, a case the lender claims it later voluntarily withdrew, and again in 2017. Her lawyers, representing Fife pro bono, successfully argued that the bank's second foreclosure suit was barred by the six-year limit and got it dismissed. But the Engel decision changed the rules. The Court of Appeals found that voluntarily ending a foreclosure suit stops the clock on the six-year time limit — even if the homeowner is never notified. The court's ruling applies retroactively to any foreclosure cases ongoing or still open to appeal at the time the decision was issued. Following the ruling, many foreclosures that expired under the six-year limit have been reopened or appealed to higher courts. Holly Meyer, a Suffolk County lawyer who represented one of the defendants in the Engel case, estimated that the number of affected homeowners could be in the tens of thousands. Fife's was one of them. In April 2021, the bank moved to renew its foreclosure suit against her — and the trial judge cited the Engel ruling as a reason to rehear the case. “I was shocked at this decision, because I had put all my faith in [the foreclosure court's] initial decision, which was in my favor,” Fife said. With Fife's best defense gone, her hopes for avoiding foreclosure now appear slim, her legal counsel acknowledged. ‘Incompetently' Managed Loans It's not uncommon for lenders to allow their right to foreclose to expire, according to real estate lawyers. “There are millions of residential loans being serviced somewhat incompetently, so these things do sometimes slip between the cracks,” said Joshua Stein, a commercial real estate lawyer. Real estate industry supporters of the Court of Appeals' decision say it made little sense for a foreclosure case to fail because of what they consider a clerical error — one that basically lets borrowers shirk their debts. “The idea that you should still be at risk because you haven't repaid the money you borrowed doesn't strike me as egregious,” Stein said. Homeowner attorneys say that cases get dropped all the time in the legal system because of technical violations of procedural requirements, and that foreclosure cases should be no different. “If you have somebody on trial for murder, but you find that their constitutional rights were violated, they go free. It's the same thing here,” Meyer said. Chief Judge Conflicted? The day after the Court of Appeals ruled on the Engel case, the law firm Greenberg Traurig, which had represented two of the plaintiffs, cheered what it called a “ground shifting” victory for lenders. “Statewide application will likely protect billions in assets for mortgage holders,” its press release claimed. Chief Judge Janet DiFiore, who wrote the majority opinion in Engel, was a Greenberg Traurig client at the time that she ruled in favor of their bank clients in that and other cases, the New York Law Journal reported in April. The firm defended her in a suit brought by judges forced into retirement as a cost-cutting measure. Defense attorneys said they had not been informed of the potential conflict for the judge who ruled against their clients. “The law's not on our side anymore, and that means that there are a number of people who will be facing foreclosure when they wouldn't have faced it a couple of years ago,” Julie Howe, a senior staff attorney at the New York Legal Assistance Group, who is representing Fife pro bono, told New York Focus. Then-Governor Andrew Cuomo swears in Janet DiFiore as the new chief judge of the New York State Court of Appeals, Feb. 8, 2016. Governor Andrew Cuomo's Office Jacob Inwald, director of foreclosure prevention at Legal Services NYC, said many of the foreclosure cases affected by the Engel decision originally stemmed from the real estate crash of 2008 and freewheeling lending leading up to it. Fife, for instance, had borrowed $731,000 against her apartment in April 2007 to pay living expenses after a disabling injury and divorce. Monthly payments were nearly $5,000, with adjustable rate mortgage that started at 8% annual interest, potentially rising as high as 15%. “I didn't know anything about mortgages,” Fife said. “I was just so happy that I was able to live on another day. I was probably the easiest take on the block.” Within a year, the bank alleged that she had fallen behind on her mortgage payments — kicking off foreclosure proceedings that her loan's holder, Wilmington Trust Association, has resurrected more than a decade later. ‘It's Really Scary' Rockland County resident Susan Azcuy is in a situation similar to Fife's — believing that she'd survived foreclosure only to find the cloud hanging over her once again. For 23 years, Azcuy and her husband kept up with the mortgage payments on their house in Pomona, including a 2005 refinancing, for which she took on a debt of $210,000 at 5.75% interest. But in 2012, after Azcuy's husband was fired from his job, they missed a payment and their lender quickly moved to foreclose. The bank voluntarily withdrew the suit in March 2016 for technical reasons but did not notify Azcuy, refiling the case the next month. It went to trial in 2019, and Azcuy won, after a key prosecution witness failed to show up. ‘We're still struggling. I was very, very hopeful to be able to continue living here.' Before Engel, this would have been the end of the case, since more than six years had elapsed since the 2012 foreclosure suit. But thanks to Engel, the six-year clock restarted in 2016 — giving Azcuy's lender another chance to sue. Due to penalties and foreclosure fees, Azcuy now owes nearly $400,000, just shy of double the amount of the 2005 refinancing. Efforts to reach a settlement or a modification with the bank have been unsuccessful, according to Azcuy's attorney, Derek Tarson of the Legal Aid Society of Rockland County. If the bank brings another foreclosure lawsuit, which Tarson believes is likely, Azcuy will not be able to rely on the defense that more than six years have passed. “It's really scary. We're still struggling,” Azcuy said. “I was very, very hopeful to be able to continue living here.” Lawmakers Respond State lawmakers have introduced two bills seeking to reverse some of Engel's effects. One measure, sponsored by Sen. Kevin Thomas (D-Nassau) and Assemblymember Helene Weinstein (D-Brooklyn), would require lenders to inform borrowers if they withdraw their demands for payment, since that action serves to stop the clock on the six-year countdown. If lenders withdraw the lawsuit but fail to notify the borrowers, the clock would keep ticking — a return to the status quo before Engel. The bill would also forbid lenders from foreclosing if any part of the loan had previously expired — a measure that would bar reviving suits against homeowners like Fife and Azcuy. The legislature is also considering a second bill, sponsored by Sen. James Sanders (D-Queens) and Assemblymember Latrice Walker (D-Brooklyn). This bill would prevent lenders from discontinuing a demand for full payment, stopping the six-year countdown clock, without the consent of the borrower. The measure also would start the countdown from the time that a mortgage holder missed a payment. Though meant to protect homeowners, the Sanders-Walker bill could actually incentivize lenders to begin foreclosure more quickly, one foreclosure defense attorney told New York Focus. “If the clock is ticking, all plaintiffs are going to want to do is get their case started,” the attorney, who asked not to be named, said. Sanders rejected the critique. “I don't think that you can further incentivize the financial institutions” to foreclose after the leeway granted them by Engel, he said. Whether either of the bills would apply retroactively to homeowners like Fife and Azcuy is an open question. “It may not be able to help those, but it is our desire,” Sanders said. “We will get guidance on whether we can do that.” Sanders said that he has spoken to Gov. Kathy Hochul and legislative leaders about his bill, and while they have not endorsed it, he said they are open to supporting it. (A Hochul spokesperson said the governor “will review all legislation that reaches her desk.” “We are making excellent progress with both, and we expect good things in the coming days,” Sanders said. (NEXT) Israeli study says COVID shot efficacy decreases dramatically after 3 months, calls for boosters British Medical Journal, November 24, 2021 A study published by The BMJ today finds a gradual increase in the risk of COVID-19 infection from 90 days after receiving a second dose of the Pfizer-BioNTech vaccine. The study was carried out by the Research Institute of Leumit Health Services in Israel. Israel was one of the first countries to roll out a large scale COVID-19 vaccination campaign in December 2020, but which has seen a resurgence of infections since June 2021. The findings confirm that the Pfizer-BioNTech vaccine provided excellent protection in the initial weeks after vaccination, but suggest that protection wanes for some individuals with time. To do this, the researchers examined electronic health records for 80,057 adults (average age 44 years) who received a PCR test at least three weeks after their second injection, and had no evidence of previous COVID-19 infection. Of these 80,057 participants, 7,973 (9.6%) had a positive test result. These individuals were then matched to negative controls of the same age and ethnic group who were tested in the same week. The rate of positive results increased with time elapsed since a second dose. For example, across all age groups 1.3% of participants tested positive 21-89 days after a second dose, but this increased to 2.4% after 90-119 days; 4.6% after 120-149 days; 10.3% after 150-179 days; and 15.5% after 180 days or more. (NEXT) 31,014 Deaths 2,890,600 Injuries Following COVID Shots in European Database of Adverse Reactions as Young, Previously Healthy People Continue to Die Health Impact News The European Union database of suspected drug reaction reports is EudraVigilance, and they are now reporting 31,014 fatalities, and 2,890,600 injuries, following COVID-19 injections. A Health Impact News subscriber from Europe reminded us that this database maintained at EudraVigilance is only for countries in Europe who are part of the European Union (EU), which comprises 27 countries. The total number of countries in Europe is much higher, almost twice as many, numbering around 50. (There are some differences of opinion as to which countries are technically part of Europe.) Total reactions for the mRNA vaccine Tozinameran (code BNT162b2, Comirnaty) from BioNTech/ Pfizer: 14,526 deaths and 1,323,370 injuries to 20/11/2021 Total reactions for the mRNA vaccine mRNA-1273 (CX-024414) from Moderna: 8,518 deaths and 390,163 injuries to 20/11/2021 Total reactions for the vaccine AZD1222/VAXZEVRIA (CHADOX1 NCOV-19) from Oxford/AstraZeneca: 6,145 deaths and 1,075,335 injuries to 20/11/2021 Total reactions for the COVID-19 vaccine JANSSEN (AD26.COV2.S) from Johnson & Johnson: 1,825 deaths and 101,732 injuries to 20/11/2021 (NEXT) Censorship = dictatorship Dr. Jessica Rose, November 29, 2021 So the censorship continues. I did a very detailed and informative interview with Frank McCaughey of Ireland on the subject of the pointlessness, potential harms and dangers with mass injecting children during this ‘pandemic' with the known non-sterilizing COVID-19 injectable products. And it has been remove Let's check out what YouTube's Community Guidelines are, shall we? YouTube's Community Guidelines: These determine what content is allowed on YouTube and help make YouTube a safe place to foster community. A safe place to foster community, eh? What kind of community are you thinkin' ‘bout there, Youtube? A community akin to an enslaved, dead-eyed mass of hypnotized automatons? If I may: no thanks on that. I'd rather live on that cat Island. So, for those of you who didn't get to see the video (I imagine that is all of you since it was up for less than 24 hours), I talked at length about the ‘don't's of injecting pre-pubescent children with experimental products for which the ingredient list is a big secret for a ‘disease' that they do not succumb to. Ah, I see now. It was because I mentioned Ivermectin. Boy. Youtube. Get with the program! Read some studies for crying out loud! And update your censorship guidelines! Make them reflect the scientific truth and not the weird false dictates of singular beings who feast on the ‘community' to increase their ‘power'. Here's what I found in their COVID-19 medical misinformation policy. Treatment misinformation: Content that encourages the use of home remedies, prayer, or rituals in place of medical treatment such as consulting a doctor or going to the hospital Content that claims that there's a guaranteed cure for COVID-19 Content that recommends use of Ivermectin or Hydroxychloroquine for the treatment of COVID-19 Claims that Hydroxychloroquine is an effective treatment for COVID-19 Categorical claims that Ivermectin is an effective treatment for COVID-19 Claims that Ivermectin and Hydroxychloroquine are safe to use in the treatment COVID-19 Other content that discourages people from consulting a medical professional or seeking medical advice Ok. I want to work backwards through the italicized points, if I may. 1. Hey Youtube. I AM a medical sciences professional. This IS my consultation. Doesn't that make your dictate of discouraging ‘consulting a medical professional' moot? I am not only not discouraging this, in addition to encouraging this, I am this. 2. Hey Youtube. GET WITH THE PROGRAM. Ivermectin has been affiliated with Nobel-ity. It's not only been awarded a prize for its safe use as an anti-parastic for decades and been doled out to literally billions of people, (including pregnant women and children) with no ill effects, it's has an excessively successful safety profile as an off-label drug in the context of COVID-19.¹ 3. It has also been clinically-tested and proven effective in the context of COVID-19 as an off-label drug - which is more than we can say about the clot shots, eh?²³⁴⁵⁶⁷⁸⁹¹⁰¹¹ 4. Based on points, 1, 2 and 3, I would recommend the off-label use of Ivermectin. As a Medical Scientist. Oh and by the way, aren't you violating your own ‘Community Standards' with your point on a ‘guaranteed cure for COVID-19'? You guys are so sure that your injections are the only way to deal with this situation. Doesn't that imply that this guarantees a cure? No wait. It doesn't. But what it does do is set a precedent and instigate a thought: there will never be a cure for COVID-19. It's incurable. Which is: true. But it's also no worse than the flu in the non-vulnerable, which is most people. Including children. So we don't need to seek a ‘cure'. Just like we don't need to seek a ‘cure' for the common cold or the flu. That's one of the things that our bloody immune systems are for and very good it - preventing disease. Viruses are EVERYWHERE. ALL THE TIME. It's not a reason to freak out. Educate yourself and others on this. It about high time people learned that we are constantly engaging and have co-evolved with viruses and bacteria for the entirety of our existences. It's what we are.¹² Our genome is 7% retrovirus. If we attempt to destroy this magnificence then we are not only stupid, but we will be destroyed in turn. Leave the immune system alone. Or rather, optimize it. Be healthy. Avoid toxins. As much as you can. Pretty simple. So there you are Youtube. You have been brought up-to-date. Now, I don't like simply bitching about stuff, even though it does feel good, so I wanted to bring it to everyone's attention that you can fight to have your content re-instated once it has been removed. However, it is not a common occurrence to have a video re-instated once it has been censored. The ones that do get re-instated typically are ones that were erroneously taken down. I think that the Youtube overlords would argue that since they are paid to enforce the dictate narrative, they cannot stand behind science and truth, and therefore, I think they would hold fast to their ‘claims' that Ivermectin is dangerous and ineffective. (NEXT) Why aren't healthcare workers speaking out about the catastrophe caused by the vaccines? Steve Kirsch, November 23, 2021 Everyone thinks that if the jabs were really dangerous, doctors and other healthcare workers would be speaking out about it. They are wrong. Here are the four main reasons they do not speak out.Two important things you need to know: 1.All the kids were recently vaccinated. 2. Kids that age NEVER get tachycardia (i.e., the medical experts I've talked to have never seen it before in their careers). Here are some reasons very few people are speaking out: 1. Delegated trust. People trust their doctors, the doctors trust other doctors and ultimately the CDC. Nobody is independently verifying the CDC is telling the truth. Doctors are really really bad in critically reading scientific studies. Mask guidelines are the PERFECT example of this. There isn't any scientific proof (well-done randomized trial) that masks work. Yet very few question the narrative (and those that do are ostracized). So everyone basically goes with the flow and the whole thing is a positive feedback loop despite zero scientific basis. See my article Masks don't work and read the accolades in the Nature article. All these experts who hailed the study never read it with a critical eye and lack the skills to do so. This is how misinformation propagates. 2.Fear of job loss. Nobody wants to lose their job. Look what happened to Deborah Conrad and others who speak out. Fired within hours after speaking out. So the lab technicians who are now seeing kids with tachycardia just keep their mouth shut. They know something is very wrong, but their job is more important. Besides, if they spoke out, it wouldn't make any difference since they are just a lab technician. Doctors have a similar problem. The medical system, despite claims of physician autonomy, actually offers very little, as it takes very little to be thrown out of the system. Medicare, the FDA, a state medical board, a malpractice insurer, the DEA, a hospital medical staff, an employer - you only have to cross one of these to have your career ruined. Combine that with the idea that most physicians wouldn't be willing to stand against a medical establishment agency such as the CDC (the ones who will have long since been ostracized) and that to do so would require a huge amount of energy and time spent on medical paper research to make a case (and most docs don't have time for that) and that most of medicine is necessarily a form of group think anyway. Then add on to it that the policy makers in large medical corporations roles are more immediately to protect the interests of the corporation than to "save the world," and you arrive at our current situation. 3.Belief that COVID is even worse than the vaccine injuries. Many people are deceived by erroneous reports that the number of vaccine cases (e.g., of myocarditis) are occurring far less often now that the vaccines have been rolled out. Dr. John Su is the big culprit here because he's never told the world that VAERS is under-reported. The pediatric cardiologists know what is going on, but they aren't going to say anything due to #1. So I see doctors tweeting the myth that “sure, there is myo after the vaccine, but the rates due to COVID are worse so the vaccine is the better of the two options.” 4.Belief that the injuries are really rare. I know a doctor who treats vaccine injured patients. He has no clue whether these are every single vaccine injured patient in the US or he's only seeing a tiny fraction of the injuries. He believes he's seeing them all so writes it off as just “coincidence” and “bad luck” since if it was the vaccine, the CDC would have spotted it. 5. Cognitive dissonance/trust in authority figures. They are so convinced the vaccines are safe (since nobody else is speaking out), that any adverse events that happen must be due to something else. Positive feedback loop. 6.Belief that they can treat you for your vaccine side effects, but that they can't treat you if you have COVID. So lesser of two evils. And of course, they think no early treatments work, so they think they are doing you a favor by telling you to get the vaccine. 7.Belief that there is no viable alternative for treating COVID and that the vaccines work. So even 100,000 dead or injured people is better than 750,000 dead people from COVID. 8. Trust in the NIH and CDC. If it was a problem, the CDC would tell people. Telling people isn't their job. Their job is to follow the direction set by the experts. 9.Fear of being ostracized. People who do research fear if they speak out they would be labelled as anti-vaxers and their research would thus be discredited. 10.Critical thinkers have been fired. Hospitals and medical facilities have already fired vaccine hesitant employees per vaccine mandates thereby self selecting for vax believers. 11. They think that the side-effects show that the vaccine is “working.” This is more of a patient thing. It's how the patients look at their adverse events… as a positive thing. (You really can't make this stuff up.) 12.They are being paid to look the other way. The federal government gave “grants” (aka BRIBES) to hospitals and physicians to promote the vaccines. If they speak out against them now, the government will demand the grants are repaid. [A physician reported this to me on Telegram. You really can't make this stuff up.] 13. They will lose their research funding if they publish their results.

In part 2 of this special 3 part series, you get to hear more of Russell's presentation at the ROR (Return on Relationships) Symposium! In this half, Russell explains how you should provide value to people before you ask them for anything. Enjoy the second half of this keynote presentation, and don't forget to check out RORUniversity.com to learn more! Hit me up on IG! @russellbrunson Text Me! 208-231-3797 Join my newsletter at marketingsecrets.com ClubHouseWithRussell.com ---Transcript--- Russell Brunson: Hey, what's up everybody? This is Russell. Welcome back to the Marketing Seekers Podcast. I hope you enjoyed the last episode for my keynote presentation at Christopher Vos' ROR Symposium. So far, in the episode number one, I had a chance to talk us through some of the history and the background of how we started building our business and I'm excited this next episode's going to be the second half of my keynote presentation. I hope you enjoy. And then afterwards, the third episode, we're actually going to, I opened up some Q & A and we had a really good time doing some of that as well. That'll be the third episode, so this episode would be the last half of my keynote presentation. I hope you enjoy it. Again, if you want to go deeper with Christopher Vos, make sure you go to roruniversity.com and get on his list, read his stuff, listen to what he is doing because he is helping a lot of people to build businesses by using relationships and really understanding how to do the stuff we talk about. I talked about Dream 100 in the Traffic Secrets book. This is what he's talking at a much deeper, much more powerful level. With that said, I'm going to cue up the theme song and when we come back, you'll have a chance to listen to second half of my keynote from the ROR Symposium. Okay. Now, I'll tell a side story because it popped in my head right now and that's what I do, right? About the time, it was after Joe Vitale promoted me, I had a list with certain sites and then I got a phone call from a guy named Tellman Knudson. Anybody here know who Tellman is? Tellman used to be big at our space. He shifted it over to more hypnosis, personal development space. But Tellman messaged me on the phone. He was like, "Hey, Russell, I had this idea. I'm building or I'm interviewing all these people and," I can't remember, "I'm going to interview you for an hour about a topic and then I'm going to put it behind the squeeze page and then everyone's going to promote the squeeze page. People are going to join my list, they'll get your interview and all the other interviews." And I was like, Uh, okay, I think that's the worst idea ever." He's like, "What do you mean?" I'm like, "I'm not going to email my list to your squeeze page so they can opt in and join your list to get my free interview. I'll just give them my free interview. Why would I do that? It does it make any logical sense." He's like, "Well, everyone's going to promote it and that way, everybody, everybody's lists, people from other lists will see you as well and it's going to be the huge thing for you." I was like, "Dude, that's the stupidest idea ever. No. No." I told him no, flat out, I was like, "This is never going to work, but good luck in your future," and I hung up, right? I was nice because on my DISC profile, I'm a high S, so I can't be mean to people. So I was like, "Okay, well, sorry." Anyway, so that happens and then fast forward three months later, all of a sudden, in one day, I get emails from everybody, Joe Vitale, the Nitro Marketing guys, all the people who are the biggest of the time, emails from everybody and I open up and it's like, "There's this guy named Tellman Knutson, the interview is on his ListBuilder and you should go check it out." And I clicked on it and went to, it was called listcrusade.com, it was his site, I went to listcrusade.com and sure enough, there's an opt-in to get all these interviews and I opted in and there's all these people's interviews. I was like, "What? How do you pull it off? You got the biggest names in the world to go and do this." And I was just perplexed, like how? I'm like, "This is the dumbest idea ever. I should have done it. If it worked, this is crazy. So I found his number, I messaged him, "Okay, tell me, I'm so confused. Can I ask you a question?" So he jumped on a call with me and I was like, "Okay. I just saw yesterday 50 people all promoted your squeeze page." He's like, "Yeah, I've added 120,000, 130,000 people to my list and the last 48 hours." And I was like, "How did you do that?" And it was so fascinating. He said, "You know what, Russell? I called 49 people and I got 49 nos in a row. First one said no, no, no, no, no. You said no. Someone said, everyone said no." And he's like, "But guess what? The 50th person," he said it was Kevin and Matt from Nitro. He said, "I called Kevin and Matt and for some reason, they said yes. And after they said yes, I was like, "Cool, do you know else would be a good fit?" And then Kevin and Matt were like, "Oh, yeah, you should get so and so and so," and then they emailed the Nitro like, "Hey, you should meet so and so and so and so," they jumped over there. Those people said yes as well." And he's like, "The next 37 people in the row all said yes." Oh, he even had Jay Abraham on the list. Anyway, he said, "The next 37 people all said yes and here we are." And I was like, "Oh, my gosh, how many of us, including me, would've stopped at the first no or the second or the third? But as soon as he got one cool kid to think he was cool, he was in. Okay? So you start thinking about this, actually, this is probably more for the women. This is embarrassing, I'm going to say this. How many you guys ever seen the movie Never Been Kissed? Drew Barrymore. Okay. Macaulay, can you act this out while I explain? Just kidding. Okay. Here's the story from Never Been Kissed. Drew Barrymore, in the movie, she's never been kissed, she graduates high school and now she's a columnist at a newspaper. She's a big columnist and her brother was the cool kid. He was the jock and the coolest kid and he graduated now he's this loser because he's graduated from high school. Anyway, she's in her day job as a columnist and they're like, "We want article from what are the high school kids doing so we need you to go undercover back to high school and find out about the cool parties and all the cool stuff." So Josie, drew Barrymore's, character goes back to high school and within five seconds, she slides back into the nerd group which they're doing chess club and all these kind of things and she's writing articles about chess club and her editor's like, "No, we don't want these articles. I want the cool kids, the drugs and all this stuff, what's happening. We want the underground dirt, that's the article we're looking for." So she tries to get in and she's like, no one will, the cool kids club will not let her in. So she's home and she's frustrated and then her brother's there and her brother's played by David Arquette and so David Arquette is jealous. He's like, "I want to go back to high school, I was the coolest kid in high school." And, and Josie's like, "There's no way, you don't understand, it's harder, it's not the same thing. If you went back to school, you wouldn't be cool." And it gives the idea for him. He's like, "No, I'm going back to school." So he somehow, and Tammy says it isn't on Netflix, I'm sure it's on Netflix. Anyway, this is your homework. Everyone go watch it. So Drew Barrymore or David Arquette's character goes back and gets in high high school somehow and she sees him in the hallway, she's like, "You can't do this. It's not going to be like, you're not going to be cool like you were before." He's like, "Watch this." So he goes into the lunch room, this is the greatest scene of all film. He's in the lunch room, he's standing up on the table and he's got this huge bucket of cole slaw and he's trying to eat the entire thing, shove it in his mouth and the whole high school's cheering him on like, "Oh," and he's eating the stuff he slams the thing down. He's like, "Oh," and that fast, he's the coolest kid in high school, everybody loves him and he's the man. And then, the next day, he's like, "Okay, I'm going to show you, Josie. I'm going to make you cool." So he goes with Josie, his sister and one of the cool kids sees him and he's like, "Oh, why are you hanging out with her?" And he's like," "Her? She's the coolest girl. She actually broke up with me, she's so cool." All this stuff. And he starts talking about how cool she is and all of a sudden, everyone's like, "Oh," and then all of a sudden the cool kids are like, "Oh, she's cool." And all of a sudden, boom, she gets sucked in. And then one cool kid thinks she's cool, the next, the next and eventually, that fast, she's cool. Okay? That was a very long story to tell you that the secret is, as soon as one kid thinks you're cool, as soon as one cool kid thinks you're cool, you're in. So Tellman Knudson, same thing. He was going back here. No, no, no, no, and he got one cool kid, Kevin and Matt from Nitro who thought he was cool and then opened up everything else. So if you guys are on this ROR thing again, a couple things that I was hoping to get through to you guys, number one is, we're shooting for the stars, that'd be amazing, but don't start there because it's going to be really hard to get in. Build your thing. Find people who are around you who are doing the same, in the same business, same industry and start building from there and start growing. As you do that, it's going to start opening more doors for you. Someone's going to introduce you to somebody else, someone else is going to introduce you and you start building this network of people and you start doing it collectively. If you do it collectively, all, what's the saying? High tide rises all boats. So it starts getting bigger and bigger and bigger and eventually, it gets easier to open the next door and the next door. And eventually, what happens is, I had this group of people, Mike Filsaime and Gary Ambrose, Brad Callen and Brad Fallon, all these people, all my friends at the time, Frank Kern, all of us who are this level and eventually, at that point, we're at the level of all these other people. But guess what? There's always a next level. And there was this guy that, oh, I looked up at this guy, crazy. He's a giant, he's got big old teeth. Anyone guess who it is? It's Tony Robbins. And Tony's the next level up here. And Tony's up there and we're all down here. And one day, somehow, one of my cool kid friends got into Tony. I don't know how or who it was or anything, but somehow, one of them got into Tony. He had a meeting with Tony and blew Tony's mind and then my friend, I actually I know, it was Mike Koenigs. Mike Koenigs got into Tony somehow, blew his mind and then, so one cool guy, cool with Tony. And then Mike Koenigs introduced him to me like, "Hey, you should meet Russell." He's so and so, and suddenly Tony, I get a, and this is the craziest experience ever, Saturday morning with my kids getting ready and the phone rings, I pick it up and it's Tony Robbins' assistant. "Hey, Tony Robbins wants to see if you can meet him today?" I'm like, "Okay, who is this?" I thought it was my friends messing with me and they're like, "No, my name's Jay Garrity, I'm Tony Robbins assistant. He's in Salt Lake City, he wants to meet with you." I'm like, "I live in Boise." They're like, "Yeah, well, he knows who you are and he meet with you. Can you get to Salt Lake?" And I'm like, "Well, it's a five hour drive. I can jump in my car." He's like, "Oh, we're flying out in three hours." He's like, "How about next week? Can you meet Tony in Toronto? He's your UPW, you can show up, go to the event, walk on fire and then he'll have a private meeting with you." I was like, "What's your name again? Is this a real person?" I'm like, "Heck yes, I'll be in Toronto next week." So the next week, I'm flying to Toronto. Again, I've never been to a Tony Robbins event so I show up with my backpack, my computer, I'm going to sit back and take notes like the internet nerd that I am. And I walk in and people are jumping and screaming and we're sitting there dancing and rubbing people shoulders and I'm so confused what's even happening. And then, we walk on fire and the first time I met Tony actually was the fire walk. He had me in a VIP section, so imagine there's 2000 people in the event and then right next to the stage, he has these two VIP sections and I actually stood next to Chuck Liddell. I didn't know who Chuck Liddell was at the time, I'm like, "That guy looks scary," big old mustache and big old muscles and I was like, but he was there. Anyway, I saw him when he went to UFC and I'm like, "That was my partner at UPW, I know everything was messed up in his life. This is so weird." Anyway. He's probably offended I had no idea who actually was. Anyway, we're in this little group so we could have a chance, to go back, the first time I met Tony is, after everyone leaves the fire walk, we walked through the front thing and they opened the curtain and Tony's standing there and he was like, "Russell, I heard so much about you," he gives me this huge hug and then we walk with him and I did the fire walk with Tony and that's my first impression. But check it out, it wasn't because I emailed Tony and tried to get to know him. I probably emailed him a lot and it never made it to the gatekeepers. But it was because one cool kid got in there and told him I was cool. And after that, it was open. Doors were open. So this is in, in my mind, this is the stuff I want you guys thinking through. Sometimes, with Dream 100, we're going to turn the relationship, we're going to give a list and we're going to send it to mailboxes and that's going to be how we grow our company. There's a place and a time for that, but that's not how it really works. It's this organic thing where it's building actual relationships, getting to know people, finding out about them and their families and how can I serve them and back here, when we're all at this level, it's like me trying to help them like, "Oh, I tried this in my business and it worked. You should try that." We're having these back and forth and it builds these relationships. And then, together, we all collectively rise up to the next level and the next level and the next level to eventually, we are the top level and that's when it gets more and more fun. So that's what I was hoping to really share with you guys, especially because I think, for some of you guys, as I'm sure for many, you look at someone who, like me, who's been doing this now for 20 years, oh, it's easy for us. Anyone will take this call. Yeah, but it's 20 years I've been playing this game. 20 years I've been putting the coins in the deposit box over and over and over and over and over again. When I found out who Dan Kennedy was, I'm like, "Okay, I want to get to know that person, but I don't know how to get there and it was like, well, there's two ways I can get into Dan Kennedy's world. I can work my way in or I can buy my way in. I'm like, working my way could take a decade or two, so I'm going to buy my way in. So I was like, "Okay, I've joined the mastermind group, I'm getting in there." And then I didn't go. I have people, oh, people that joined my mastermind group this last time around, amazing group, but there's different, everyone's got a different mindset and I have people coming in initially and they're like, "Russell, this is so cool. Can I make a testimony with my video? Hey, can I get a picture?" And they were trying to take, take, take, take, I'm like, "Ah." When I went to Dan Kennedy's group, guess what I didn't do? I didn't take from Dan. First off, because I'm scared of him. Number two, I was like, all right, I'm going to serve these guys because I want Dan to know who my name is. I don't want me to message Dan, I want people telling Dan who I am. If I can do that, that's the secret. So I'm in Bill Grazer's group, I'm serving the group, I'm trying to help as much as possible. I'm helping these offline people in this group to launch online businesses. I'm helping them get funnels. I'm helping them do the launch, I'm doing coordination. All this stuff to serve Bill Grazer's group. And Bill's like, "Oh, my gosh, Russell's really helpful." And he tells Dan, "Dude, this guy in our group, he loves you, he loves everything, he's helping our group." And I always wanted to speak at Dan's event, but I'm like, I'm not going to ask him because I don't want to do it, but I'm just going to keep serving and eventually, he's going to have to, because I do so much stuff for so many people, they're going to want to put me on stage. So I get in that group and I'm serving like crazy. In fact, after, I think it was three years in, I wanted to, anyway, I had to fly to Baltimore three times a year and it's not just flying to Baltimore, Bill was in Baltimore. You'd fly to Baltimore and then you'd drive in a taxi for an hour to get to the hotel that Bill would have it at, and after three years I was like, "I can't do this anymore." So literally, I messaged Bill, I'm like, "Hey, I'm not going to re-up this next year because I just can't keep coming to Baltimore." And he literally was like, "This is the deal, Russell, you have to be in the room so you're not going to have to pay anymore, but you're still coming." I was like, "Okay." And for the next three years, I didn't pay but I kept showing up because I provided so much value, he's like, "You have to be in this room because you're facilitating all these things." And then he had me on stage, had me on stage again and then eventually, I remember the last event I spoke at, I spoke on stage four times. I was on stage longer than Dan Kennedy was. Do you think Dan Kennedy knew my name? Yes, he did. He was like, "There's this internet nerd who keeps showing up and helping everybody, he's never asked for anything. We should get to know him," and that's how I built a relationship with Dan and then with Bill and with all these kind of things. And now, fast forward a couple years later, the opportunity to buy Dan's company's there and I'm like, what if he hates me? Because he's not going to approve ... And I literally, I faxed him because you can't email Dan, he has no email, you have to fax him. So I had to open an eFax account, write it on a piece of paper, send it, it's this whole thing. So I faxed him, I was like, "Hey, there's an opportunity to buy your company, but I just want to make sure that you don't hate me or I'm not ... We're going to be working together so I want to make sure this is going to be a good fit." And he faxes me back, he was like, "Dude, every time I've heard about you, it's you on stage talking about how good I am, you always praise my name, all these kind of things. Of course, I would love to work with you," because he knew who I was. I had been trying to serve him for all this time and I'd never asked him for something so because of that, he said yes. And now we're have this partnership and we're 30 days away from watching the new magnetic marketing and you guys are going to die when you see this, it's the most exciting thing ever, but it all came off of that, building these relationships over the long term. If you guys haven't, on YouTube, there's a video, if you type in "Russell Brunson Tony Robbins Dream 100," there's a video documenting my Dream 100 process with Tony, which was over a decade and a half to do this thing, the very first time he actually promoted me. But it wasn't me coming in like, "Tony promote, Tony, promote." If I would've done that, I would've had one meeting with Tony and that would've been the last. It was a decade of me just, every meeting with Tony, "How can I help? How can I help?" People from this company would call like, "Hey, can you consult us on this thing?" I'm like, "Yes." "How much does it cost?" I'm like, "For Tony, it's free." "I'm sure your time's valuable, we're willing to pay you." "No, tell Tony, your money's no good with Russell," because I wanted the relationship. And fast forward now, I'm going to get emotional. Oh. This isn't a story that we've publicly told, but you guys know Funnel Hacking Live, Dave had his cancer, if you know the real story, it's literally the worst kind of cancer you have, they give them like a 6% survival rate past eight months, 10 months, something like that. So we were so scared and after Funnel Hacking Live, after Tony off stage, went backstage with him and Tony was like, "How can I serve? What else, what can I do for you guys?" And Todd had the impression, "Hey Tony, this is our friend and partner Dave. He's dying. Is there anything you can do?" And Tony says, "Yes, these are the people. Call this person, call this person. In fact, I'll connect you. Here's the people." Two weeks later, Dave's flying to Dallas, he's with this doctor who does things the opposite of what every other cancer doctor does, Dave spends two weeks down there with him. I won't get too deep into the details, but discovers there's a root canal that causes the tumor, pulls his tooth out, throws the oxygen in there, oxygens his body, does a bunch of things. Two days later, Dave goes back for his MRI where they're supposed to tell him how long he's got left so he can plan with his family. They do an MRI, the doctor looks inside and says, "There's not a bit of cancer inside you. What did you do the last two weeks?" And because of my relationship with Tony, I had access to this guy who saved Dave's life. And Dave's going to be here for the next 20, 30 years because I was willing to put in, for a decade and a half, this relationship with Tony and Tony had a relationship with these other guys and man ... So is it worth it? Yes. Is it worth financially? Yes. Is it worth it from so many more things? Yes. It is. So I'm forever grateful that I didn't ask Tony to promote my thing on day one. I'm forever grateful that I didn't try to figure out what I could take. I'm forever grateful that when they asked for help, I just gave it because I love Tony and because that opened all these doors where, yeah, so whew, not planning going there, but that's the power of this stuff. So when Christopher's talking about this, I'm sure he is told his story. He had a very similar situation where, because of the relationship, his life was saved. So you never know, it's coming into these things not looking for something, but coming in as a servant. And as you have that servant feeling and you're going into it, it's amazing what doors open and you never know what door you're going to need or when you're going to need it or what the thing is or what the, you know what I mean? It's crazy. Whew. I don't know how I wrap that up or how to- Don Mamone: Do you need a minute? Do you need a minute? I mean, I'm going to step in and just say, take a drip of water. That's probably one of the most amazing stories and I have to say that you, unknowingly maybe, and the reason you needed to tell that story was because we had an ongoing over-under bet on how long it takes a speaker to cry on Christopher's stage because so many people have come up and told stories from the depths of their heart and soul. So, hey, I want to thank you for joining those of us that have joined Christopher's stage in which you have an over-under on telling an emotional story, so thanks for that, Russell. Russell: No worries. You set a environment where it was there. Anyway. Yeah, I hope that this was helpful for you guys. Again, I was like, I could go and give you guys the foundation and step one and step two and step three, stuff we talked about here, but I was like, I don't want to do that. I want to be real as possible because it's real in so many aspects of your life. And now's the time, wherever you are, is to start planting those seeds and starting looking at who can you serve, who can you serve and the more you do that, the more doors open and the more things. And it's okay eventually because I think sometimes, people are scared to ask and I would tease Christopher about this. He's been building a relationship with me for now, I don't even know, three or four years and we used to have a joke inside of the office, "What's he going to ask?" Somebody's going to ask something. "I don't know. Maybe he's just going to keep serving and serving and never ask." And then when he finally is like, "Hey, I'm doing this thing, would you be willing?" "Finally, thank you for asking." Because we know, there's always, all of us, when I was dating my wife, I was asking her on a date and she knows my intentions. If I already came date number one, "Hey, can we get a picture just in case if we get married, we'll have the ... " Whatever. If I'd done these weird things along the way, it wouldn't have worked, but like everyone knows, we're in business, we're in things like that, we know what the goal is, but we're trying to feel people out to see if they're genuine or not. It's interesting. I heard Adam Sandler talk about it one time and he was like, "I don't have very many friends." He said the reason why is because, he's like, "Earlier in my career, as I started having more success, everyone wanted be my friend. I realized really quickly they didn't want to be my friend, they wanted something from me." And the higher tier you get, you'll find out that happens. For me, I don't have a whole bunch of friends because I don't know who my friends are a lot of times. It's interesting because there was a time in my life where I thought everyone who was coming was my friend and I started giving people jobs and some of you have heard the story, I built a huge company of over a hundred people and I thought they were my friends and were here because of the mission, because of the vision. And when we had a hiccup and things kind of crashed, they all went away. And it was interesting because thought that they were coming for that. I can't remember exactly where I was trying to go with this train of thought, but ... Oh, yeah. At the higher levels, just Understand that their guards are up because they've been burned in the past and it's like, who's true friends? And if you show up as a true friend where you're giving, you're serving, they know you want to do something with them eventually anyway, that's in the back of their mind, but they're testing, is this person the person who's coming because they're trying to get something from me or someone who genuinely wants to be a friend or genuinely wants to help, genuinely wants to do something? So it's just consistently showing up for a long time and maybe it's not as fast to turning on a Facebook ad, but for the long term stability, what you're trying to do, it's the best thing. Anyway, I hope that helps. I hope that gave somebody something today.

Bill Apter, formerly of Pro Wrestling Illustrated magazine, talks to the "1990 Pro Wrestling Illustrated Rookie Of The Year" (that's Steve Austin in case you're wondering) about Buddy Rogers, the death of the territories, the Von Erich family legacy, Gary Hart, Eddie Graham finishes, the Andy Kaufman-Jerry Lawler feud, Hulk Hogan in Rocky III, and the MRI machine that almost got the best of our favorite G.I.A.N.T. (global icon and national treasure). Enter to win a free membership to Planet Fitness for an entire year PLUS a $500 gift card! Take better control of your health, both body and mind! Get CON-CR?T into your life today. Register now at CON-CRET.com/podcast. THAT'S CON-CRET.COM/PODCAST TO LEARN MORE!