Podcasts about biomedical research

To discuss a novel treatment for Mosquitoes with Malaria, John Maytham is joined by Dr Dale Taylor | Malaria Researcher at the H3D Centre, University of Cape Town. Presenter John Maytham is an actor and author-turned-talk radio veteran and seasoned journalist. His show serves a round-up of local and international news coupled with the latest in business, sport, traffic and weather. The host’s eclectic interests mean the program often surprises the audience with intriguing book reviews and inspiring interviews profiling artists. A daily highlight is Rapid Fire, just after 5:30pm. CapeTalk fans call in, to stump the presenter with their general knowledge questions. Another firm favourite is the humorous Thursday crossing with award-winning journalist Rebecca Davis, called “Plan B”. Thank you for listening to a podcast from Afternoon Drive with John Maytham Listen live on Primedia+ weekdays from 15:00 and 18:00 (SA Time) to Afternoon Drive with John Maytham broadcast on CapeTalk https://buff.ly/NnFM3Nk For more from the show go to https://buff.ly/BSFy4Cn or find all the catch-up podcasts here https://buff.ly/n8nWt4x Subscribe to the CapeTalk Daily and Weekly Newsletters https://buff.ly/sbvVZD5 Follow us on social media: CapeTalk on Facebook: https://www.facebook.com/CapeTalk CapeTalk on TikTok: https://www.tiktok.com/@capetalk CapeTalk on Instagram: https://www.instagram.com/ CapeTalk on X: https://x.com/CapeTalk CapeTalk on YouTube: https://www.youtube.com/@CapeTalk567 See omnystudio.com/listener for privacy information.

Send us a textDr. Sui Huang, MD, PhD is a Professor at the Institute for Systems Biology ( ISB - https://isbscience.org/people/sui-huang-md-phd/?tab=biography ) where his lab is focused on studying how gene regulatory networks control gene activity to create stable cellular states, such as different cell types, and how these states transition into different lineages in both healthy and diseased conditions.Dr. Huang is a molecular and cell biologist with a strong background in theoretical biology and has devoted much of his research to understanding the very phenomenon of cancer from a complex systems perspective. Before joining the ISB in fall 2011, Dr. Huang held faculty positions at the University of Calgary (Institute of Biocomplexity and Informatics), where he helped establish biocomplexity as a discipline in research and teaching, and at Harvard Medical School (Children's Hospital) where he obtained first experimental evidence for the existence of high-dimensional attractors in mammalian gene regulatory networks.Dr. Huang grew up in Geneva and Zurich. He received his MD degree from the University of Zurich and obtained thereafter, as the first recipient of the PhD-Program-for-Physicians Award of the Swiss National Science Foundation, his PhD in molecular biology and physical chemistry for work on interferons. As a postdoctoral fellow at Children's Hospital Boston he investigated tumor angiogenesis and cell growth control. In that period he also studied dynamical systems through his affiliation with the New England Complex Systems Institute.Important Episode Link - "The end of the genetic paradigm of cancer" - PLOS Biologyhttps://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3003052#SuiHuang #InstituteForSystemsBiology #Interferon #Angiogenesis #AttractorStates #Epigenetics #Cancer #Oncology #TumorMicroenvironment #DonaldIngber #ConradWaddington #Organogenesis #Morphogenesis #LeeHood #BeatriceMintz #ProgressPotentialAndPossibilities #IraPastor #Podcast #Podcaster #Podcasting #ViralPodcast #STEM #Innovation #Science #Technology #ResearchSupport the show

BrainStorm wants to hear from you! Send us a text.in this episode of the "BrainStorm" by UsAgainstAlzheimer's, George Vradenburg, Co-founder and Chairman of UsAgainstAlzheimer's, and Russ Paulsen, the organization's Chief Operating Officer, discuss the impact of the Trump administration's policies on Alzheimer's research with host Meryl Comer. The conversation highlights the systematic dismantling of the National Institutes of Health (NIH) and other critical agencies, which threatens to undermine Alzheimer's research and public health. Vradenburg and Paulsen express concerns about the lack of transparency in the reorganization and the potential negative effects on drug reviews and approvals due to significant cuts at the FDA. They highlight the importance of protecting key programs that support seniors and the potential global impact of these policy changes. Despite the challenges, both Paulsen and Vradenburg are optimism about scientific advances in diagnosing and treating Alzheimer's, including the development of blood tests and new treatments. Hear the call to action for listeners to advocate for continued support for Alzheimer's research and to contact their members of Congress to ensure that funding remains a priority. This is a must listen episode!  This episode is sponsored by Genentech.Support the show

What happens when a Republican author slams Trump's tariffs, calls out Medicare cuts, and pushes back on RFK Jr.'s health claims—all on a progressive podcast?In this episode of Lean to the Left, host Bob Gatty speaks with Michael Goodwin, Florida Republican and author of the political satire Vice Versa. With Wall Street experience and a sharp pen, Goodwin offers a rare, candid take on Trump's economic missteps, the Supreme Court's troubling direction, and the damage being done to Medicaid, Medicare, and biomedical research.

The Future of AI in Pharma & Biotech Research #aiinbiotech #pharmaresearch #drugdiscovery AI is fundamentally changing the way biotech and pharmaceutical research happens. From analyzing vast datasets to accelerating drug discovery, AI-powered solutions are making labs smarter, faster, and more efficient. But how does it actually work? Please visit our website to get more information: https://swangroup.net/ In this episode, I sit with Liran Belenzon, CEO of BenchSci, to explore how AI reshapes pharmaceutical research. We discuss:✅ The biggest challenges of working with scientific data✅ Why big pharma companies prefer AI-powered platforms over in-house solutions✅ How multimodal AI enhances lab efficiency and accelerates drug developmentLiran also shares his journey from being an MBA student to leading a company that works with 12 of the world's top 20 pharma companies. If you're curious about the intersection of AI, biotech, and research, this episode is a must-watch. Let's talk about the future of AI in biotech. What excites you the most? Let me know in the comments. Links from this episode:✅ Get to know more about Liran Belenzon: https://www.linkedin.com/in/liranbelenzon ✅ Learn more about BenchSci: https://www.benchsci.com ✅ Follow BenchSci for updates on AI in biotech: https://ca.linkedin.com/company/benchsci 

We want to hear from you! Send us a text.Journalist and author Greg O'Brien, diagnosed with early-onset Alzheimer's over a decade ago, shares with BrainStorm host Meryl his determination to be heard at the Washington D.C. rally at the Lincoln Memorial to protest proposed cuts to NIH biomedical research funding that would critically affect Alzheimer's disease research.  Greg also candidly shares what it takes for him to navigate at this late stage in the disease.This episode also features a TopLine commentary by George Vradenburg, founder and chair of UsAgainstAlzheimer's, on the mobilization of patient advocacy organizations across diseases fighting to maintain the integrity of America's biomedical and scientific research.This episode is sponsored by Genentech.Support the show

這集三腳貓新手村一起來聊聊大家開始怎麼漸漸習慣美國生活的呢？大家都是如何把美國當作自己的第二個家呢？來聽聽天豪、若晴及雯薇的經驗吧！ 大城市 vs 小城市 民以食為天！ 極度縮水的spinach 西方超市 vs 亞洲超市 Meal prep是讓人可以開始在家裡做東西的動力之一 一不小心吃的就講了一個小時 該如何為不同的美國氣候準備衣服呢？ Outlet及連假特價是購入衣服的好時機 圖書館有很多好用的資源！ 運動的資源很多，記得要多運動維持自己的身體健康 學會醫療保險及Student health的運作及使用方式 生小孩的帳單是多少？想知道更多的請留言！ 善用信用卡點數的點數玩家們 可以先從cash back開始累積信用 其實仔細找找也有學生票或是免費的藝文活動 大家當初想要給自己的一句話：請早點開始用退休金帳戶Roth IRA!!!! 貓與小孩 冥想 結尾：生活也是能讓自己長久追求夢想的重要因子之一 工作人員 內容製作：雯薇、若晴、天豪 後製：雯薇 文案：雯薇 音樂：雯薇 封面：雯薇 上架：雯薇 宣傳：Angel、雯薇 -- Hosting provided by SoundOn

A panel discussion of a Presidential Advisory from the American Heart Association that outlines the importance of funding for scientific research and the need for a robust National Institutes of Health. This podcast is intended for healthcare professionals only. To read a transcript or to comment, visit https://www.medscape.com/author/bob-harrington INCLUDE URLS and full titles for some of the pertinent studies cited. You may also like: Principles for the Future of Biomedical Research in the United States and Optimizing the National Institutes of Health: A Presidential Advisory From the American Heart Association https://doi.org/10.1161/cir.0000000000001319 The Role of Public-Sector Research in the Discovery of Drugs and Vaccines." https://www.nejm.org/doi/full/10.1056/NEJMsa1008268 Comparison of Research Spending on New Drug Approvals by the National Institutes of Health vs the Pharmaceutical Industry, 2010-2019 https://pubmed.ncbi.nlm.nih.gov/37115539/ Hear John Mandrola, MD's summary and perspective on the top cardiology news each week on This Week in Cardiology https://www.medscape.com/twic Questions or feedback, please contact news@medscape.net

Synopsis: Building in biotech isn't for the faint of heart—especially during a market downturn. But that's exactly when Steve Tregay, Managing Partner at Mission BioCapital, thrives. A seasoned entrepreneur and founder of Forma Therapeutics, Steven has navigated biotech's toughest cycles—and emerged stronger each time. Hosted by Rahul Chaturvedi, this conversation dives into what it really takes to launch and scale biotech companies: from mastering the evolution of the CEO role to raising nearly $900M through strategic partnerships, to knowing when it's time to pass the torch. Steve also shares how Mission BioCapital is rewriting the playbook for early-stage innovation through its Platinum Program, offering $500K and lab access to science founders ready to launch bold new ideas. Real talk, real strategies, and a blueprint for building lasting biotech companies—especially when its hardest. Biography: Steve Tregay, PhD is a Managing General Partner based in our Cambridge office. He focuses on new therapeutics investments with a particular emphasis on company creation opportunities as well as on overall management of the firm. Within the Mission BioCapital portfolio, he is currently founding CEO and board member of Arclight Therapeutics, LLC, a founding board member at Jupiter BioVentures LLC, and has board roles at Vedere Bio and Nocion Therapeutics. In addition, Steve serves as Chairman of the Board of Directors at LabCentral. He is a Harvard Blavatnik Biomedical Accelerator Advisory Committee member and is a member of the board of advisors for the non-profit Life Sciences Cares. Previously, Steve was the Founder and CEO of FORMA Therapeutics. Additional roles held prior to his engagement at FORMA include Managing Director for the Novartis Venture Fund and Executive Director & Head of Strategic Alliances for Oncology, Ophthalmology and Technologies at the Novartis Institutes for BioMedical Research. Prior to Novartis, he held roles in research and business development at Array BioPharma. Steve received his doctoral and Master's degrees in organic chemistry from Harvard University and a Bachelor's from Davidson College.

Former NIH director Dr. Harold Varmus speaks out about what recent budget cuts and policy changes could mean for science.One of the areas targeted by President Trump's administration for cuts has been the National Institutes of Health (NIH). Cost-cutting actions have included the layoffs of some 1,200 NIH employees, the termination of research grants, a pause in the “study sections” that evaluate and award grant funding, and a cap on indirect costs included in research grants. Some of those moves have been paused following court cases. Dr. Harold Varmus, a former director of the National Institutes of Health, joins Host Ira Flatow to talk about the actions, and the impact he fears they could have on the future of biomedical research in the United States.Transcripts for each segment will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

Reproductive health is historically understudied and underfunded in the United States. Scientists across Connecticut and beyond have been working to change that. Scientific initiatives like EndoRISE, a Connecticut-based program focused on advancing endometriosis research, are making strides toward better understanding reproductive health. This hour, we explore how President Trump’s recent funding cuts could impact their progress. GUESTS: Michayla Savitt: State Government Reporter, CT Public Dr. Danielle Luciano: Associate Professor of Obstetrics and Gynecology and co-director of EndoRISE Dr. Lubna Pal: Professor of Obstetrics, Gynecology & Reproductive Sciences, Yale School of Medicine Julie Rovner: Chief Washington Correspondent, KFF Support the show: http://wnpr.org/donateSee omnystudio.com/listener for privacy information.

原本會成為一名，要用簡單易懂的語言，引導小學生快樂成長的國小老師。Melinda在一次無心插柳下的「大學人生小探險」，居然走著繞著，就這樣走上了生醫研究的道路，也在這條路上遇到幾位風格各異的學術導師，帶著她逐漸穩步向前，從台灣的插花生醫實驗室小工，一路走到現在，成為OMRF的博士後研究人員。繼上次來介紹奧克拉荷馬之後，讓我們再來聽聽Melinda分享，她這相較之下，不那麼典型的生醫職涯起步歷程，以及她從幾位指導教授身上，學習到什麼各式獨門神技，並且對她的人生思考及未來規劃有些什麼影響。 喔對了！想知道Melinda有沒有在今年的state fair吃到炸小熊軟糖嗎?這集也會公佈結果喔！ *本集勘誤：Dr. Rod McEver發現的是P-selectin，不是PECAM1 延伸閱讀 何彥君實驗室網頁 https://www.ibms.sinica.edu.tw/yen-chun-ho/ch/ Melinda博後實驗室主持人Courtney Griffin的TED演講** **https://www.youtube.com/watch?v=JTBg6hqeuTg 工作人員 內容製作：Melinda、Angel、天豪 後製：天豪 文案：天豪 音樂：雯薇 封面：雯薇 上架：天豪 宣傳：Angel、雯薇 -- Hosting provided by SoundOn

In this episode of Molecule to Market, you'll go inside the outsourcing space of the global drug development sector with James Lovett, CEO and Mike Cohen, Executive Chairman at Myonex. Your host, Raman Sehgal, discusses the pharmaceutical and biotechnology supply chain with James and Mike, covering: How a family-owned pharmacy became a major global clinical trial supplies business... two generations later Mike's decision to bring in a CEO and the challenge of letting go... before seeing the data points of success James' decision to take on the baton and fuel organic and inorganic growth through client-centricity The decision not to take investment and instead 'run our own play' using some of PE's tried and tested playbook Why this industry will always grow due to unmet medical needs and breakthroughs in science Michael's passion and commitment have been a driving force in making Myonex, a global leader in clinical trial supply. Under his leadership, Myonex has expanded its service offerings and strengthened manufacturer and sourcing relationships, opened new locations and expanded the employee base. Today Michael focuses on strategic growth opportunities. Before Myonex, he served in executive positions in the publishing, advertising, financial and utility industries. He holds a BS in Statistics from the University of Pittsburgh and an MBA from the university's Katz Graduate School of Business. James is driven to help clients deliver medical advances, to develop team members, and to lead Myonex to continued success. Before joining Myonex in 2017 as Chief Operating Officer, James was SVP of Covance, where he led three business units, was General Counsel and served on the Executive Committee. He was named Myonex CEO in 2019. He also serves on the Board of Directors of Food Chain ID and the Board of Trustees of the Wistar Institute. James has played leadership roles in the Association of Clinical Research Organizations and the National Association for Biomedical Research. He is a graduate of Northwestern University and Harvard Law School.   Please subscribe, tell your industry colleagues and join us in celebrating and promoting the value and importance of the global life science outsourcing space. We'd also appreciate a positive rating! Molecule to Market is also sponsored and funded by ramarketing, an international marketing, design, digital and content agency helping companies differentiate, get noticed and grow in life sciences.

Piper speaks with Dr. Pouya Dini about UC Davis producing equine embryos by in vitro fertilization. Dr. Anna Dunaway of Purina Animal Nutrition talks about equine weight management strategies owners can use to have a meaningful impact on weight and body condition score. Dr. Gus Cothran also joins to talk about new research on the Y chromosome that will allow geneticists to trace the paternal line in horses. Brought to you by Taylor, Harris Insurance Services.Host: Piper Klemm, publisher of The Plaid HorseGuest: Dr. Pouya Dini is an associate professor at the Department of Population Health and Reproduction and the chief of the Equine Reproduction Service at the School of Veterinary Medicine at the University of California. He is a Diplomate of the European College of Animal Reproduction and the American College of Theriogenologists. Pouya holds two PhD degrees. The first PhD he obtained was a collaboration between Azad University and the University of Ghent, Belgium, and the second PhD was a collaboration between the University of Ghent and Gluck Equine Research Center at the University of Kentucky. His current research interests include the pathophysiology of the equine placenta and embryo development at the genomic level. Pouya is also the Director of the Veterinary Assisted Reproduction Laboratory, a research facility and a national embryo service provider for breeders and veterinarians located at the Department of Population Health and Reproduction at the School of Veterinary Medicine at UC Davis. Guest: Dr. Anna Dunaway is a Nutritionist on the Equine Technical Solutions team at Purina Animal Nutrition. Her Ph.D. research at the University of Nebraska focused on the use of high fat diets and manipulating the microbial community in the gut. Now at Purina, Dr. Dunaway's role includes bringing innovative solutions like the Equine MQ™ Platform from the research team out to the field.Guest: Dr. Gus Cothran was born and raised in Texas and graduated from North Texas State University where he obtained his BS and MS degrees in Biology. He then received his Ph.D. in genetics from the University of Oklahoma. Dr. Cothran worked at the University of Georgia's Savannah River Ecology Laboratory, then at the Southwest Foundation for Biomedical Research where he worked on the genetics of horses. From there, he moved to the University of Kentucky and was the Director of the Equine Parentage Testing and Research Laboratory, and Research Professor in the Department of Veterinary Science. In 2006, Dr. Cothran moved to Texas A&M University, where he was a Clinical Professor in the Department of Veterinary Integrative Biosciences. In 2016, Dr. Cothran retired but was named as an Emeritus Professor and he remains active in research activities. Dr. Cothran was a four-time Chair of the International Society of Animal Genetics standing committee for Thoroughbred DNA Typing Standardization, and a past chair of the Equine Standing Committee.Title Sponsor: Taylor, Harris Insurance ServicesSubscribe To: The Plaid Horse MagazineSponsors: Show Strides Book Series, Good Boy, Eddie and Geoff Teall on Riding Hunters, Jumpers and Equitation: Develop a Winni

Happy New Year! For many of us, a new year brings a renewed sense of motivation when it comes to health. Earlier this year, Russ sat down to speak with Jonathan Long, a Stanford biochemist who studies the chemicals produced during exercise. The conversation was one of our most popular during 2024 and today we're re-sharing it. As many of us look to create healthy habits in 2025, we hope you'll tune in to hear the exciting research Professor Long is doing to better understand the deep chemical connections between diet, exercise, and human health. Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your quest. You can send questions to thefutureofeverything@stanford.edu.Episode Reference Links:Stanford Profile: Jonathan Z. LongJohnathan's Lab: LongLab@StanfordConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / FacebookChapters:(00:00:00) IntroductionHost Russ Altman introduces guest Johnathan Long, a professor of pathology at Stanford University.(00:01:55) Effective Weight Loss DrugsThe history and development of GLP-1 receptor agonists.(00:03:27) Understanding Metabolism and ExerciseThe role of metabolic chemicals released during physical activity.(00:05:02) Animal Models in Exercise Studies The use of animal models in exercise studies and the discovery of Lac-Phe.(00:06:40) Psychological Preparation for Exercise The psychology of exercise preparation and the involvement of endocannabinoids.(00:08:53) Lac-Phe's Role and Mechanism Lac-Phe's role in suppressing appetite and its production in the gut.(00:11:46) Differences in Exercise Response Exercise response between trained athletes and untrained individuals.(00:12:50) Diabetes and Metabolic Diseases The relationship between diabetes, exercise, and metabolic diseases.(00:14:54) Lac-Phe as a Potential Therapeutic Lac-Phe's potential and parallels to the early stages of GLP-1 drug development.(00:16:13) Importance of How Weight is Lost The importance of losing fat while preserving lean muscle mass.(00:19:04) Exercise as Medicine The need to define physical activity at the same resolution as modern medicines.(00:22:03) Metformin and Exercise Pathways The unexpected connection between metformin and the Lac-Phe pathway.(00:23:53) Prospects of an Exercise Pill The future of an exercise pill, and challenges associated with its development.(00:26:57) Conclusion  Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook

Send us a textThis week we spoke to Dr. Colm Collins! Dr. Collins is an Associate Professor at the Conway Institute of Biomolecular and Biomedical Research at University College Dublin. He shares his journey from the world of pharmacology to pioneering research in inflammatory bowel disease (IBD). You'll learn about the innovative approaches his team is exploring to revolutionize treatment options for IBD patients. With a blend of humor and expertise, Dr. Collins offers a rare glimpse into the challenges and triumphs of translating scientific breakthroughs into real-world health solutions.Our conversation unravels the intricate relationship between the immune system and gut bacteria, as Dr. Collins explains how retinoic acid and microRNAs play crucial roles in managing IBD. We delve into the promising possibilities of replacing lost proteins and the therapeutic potential of cannabinoids, exploring their implications on both the immune system and the digestive tract. Amidst the science, we tackle the ethical and legal complexities of cannabis research, particularly in adolescents, as Dr. Collins shares his experiences navigating these challenges with integrity and humor.Join us for an enlightening discussion that balances serious scientific inquiry with light-hearted anecdotes, as Dr. Collins recounts his experiences in Colorado and discusses the future of IBD treatment. From the nuances of cannabis use in managing IBD symptoms to the exciting potential of selective human receptor-modifying peptides, this episode promises to expand your understanding and offer hope for more effective therapies on the horizon. Plus, enjoy a humorous account of altitude adaptation and its quirky effects on newcomers and the unexpected twists in cannabis research funding.Links: Journal article: Manipulation of the Endocannabinoid System in Colitis: A Comprehensive ReviewJournal article: Adherence, Safety, and Effectiveness of Medical Cannabis and Epidemiological Characteristics of the Patient Population: A Prospective StudyInformation on medical cannabis and IBD: Crohn's & Colitis Foundation- USAResearch funding opportunities- Crohn's & Colitis Foundation- USALet's get social!!Follow us on Instagram!Follow us on Facebook!Follow us on Twitter!

Mike回來啦，這集Mike跟若晴各自挑了一些新聞來跟大家分享，來聽聽看這次聊的有什麼有趣的吧！ 連結： RFK and Vivek: https://endpts.com/what-is-the-future-of-the-trump-admins-pharmaceutical-policies/ Recursion's Facebook: https://endpts.com/ai-focused-biotech-recursion-underwhelms-with-first-phase-2-readout/ Howard Chang to be Amgen's CSO: https://endpts.com/amgen-names-geneticist-and-biotech-founder-to-chief-science-role/ 節目內容： Mike回歸第一次錄音就出包 若晴開會順便去巡田水遇到聽眾 德州烤肉牛肋獨走整個岔題 竟然聊起12強 可能的新部長？ 墓仔埔也敢去 Amgen新CSO Recursion近期的臨床結果 針對腫瘤開發藥物的AI新策略 BioNemo的開源 整個開聊AI起來 -- Hosting provided by SoundOn

* List of Discoveries Squeezing Evolution: Did you know that dinosaurs ate rice before rice evolved? That turtle shells existed forty million years before turtle shells began evolving? That insects evolved tongues for eating from flowers 70 million years before flowers evolved? And that birds appeared before birds evolved? The fossil record is a wonderful thing. And more recently, only a 40,000-year squeeze, Neanderthal had blood types A, B, and O, shocking evolutionists but expected to us here at Real Science Radio! Sit back and get ready to enjoy another instant classic, today's RSR "list show" on Evolution's Big Squeeze! Our other popular list shows include: - scientists doubting Darwin - evidence against whale evolution - problems with 'the river carved the canyon' - carbon 14 everywhere it shouldn't be - dinosaur still-soft biological tissue - solar system formation problems - evidence against the big bang - evidence for the global flood - genomes that just don't fit - and our list of not so old things! (See also rsr.org/sq2 and rsr.org/sq3!) * Evolution's Big Squeeze: Many discoveries squeeze the Darwinian theory's timeframe and of course without a workable timeframe there is no workable theory. Examples, with their alleged (and falsified) old-earth timeframes, include: - Complex skeletons existed 9 million years before they were thought to have evolved, before even the "Cambrian explosion".- Butterflies existed 10 million years before they were thought to have evolved. - Parrots existed "much earlier than had been thought", in fact, 25 million years before they were thought to have evolved. - Cephalopod fossils (squids, cuttlefish, etc.) appear 35 million years before they were able to propagate. - Turtle shells 40 million years before turtle shells began evolving - Trees began evolving 45 million years before they were thought to evolve - Spores appearing 50 million years before the plants that made them (not unlike footprints systematically appearing "millions of years before" the creatures that made them, as affirmed by Dr. Marcus Ross, associate professor of geology). - Sponges existed 60 million years before they were believed to have evolved. - Dinosaurs ate rice before it evolved Example - Insect proboscis (tongue) in moths and butterflies 70 million years before previously believed has them evolving before flowers. - Arthropod brains fully developed with central nervous system running to eyes and appendages just like modern arthropods 90 million years earlier than previously known (prior to 2021, now, allegedly 310mya) - 100 million years ago and already a bird - Fossil pollen pushes back plant evolution 100 million years. - Mammalian hair allegedly 100-million-years-old show that, "the morphology of hair cuticula may have remained unchanged throughout most of mammalian evolution", regarding the overlapping cells that lock the hair shaft into its follicle. - Piranha-like flesh-eating teeth (and bitten prey) found pushing back such fish 125 million years earlier than previously claimed   - Shocking organic molecules in "200 million-years-old leaves" from ginkgoes and conifers show unexpected stasis. - Plant genetic sophistication pushed back 200 million years. - Jellyfish fossils (Medusoid Problematica :) 200 million years earlier than expected; here from 500My ago. - Green seaweed 200 million years earlier than expected, pushed back now to a billion years ago!  - The acanthodii fish had color vision 300 million years ago, but then, and wait, Cheiracanthus fish allegedly 388 million years ago already had color vision. - Color vision (for which there is no Darwinian evolutionary small-step to be had, from monochromatic), existed "300 million years ago" in fish, and these allegedly "120-million-year-old" bird's rod and cone fossils stun researchers :) - 400-million-year-old Murrindalaspis placoderm fish "eye muscle attachment, the eyestalk attachment and openings for the optic nerve, and arteries and veins supplying the eyeball" The paper's author writes, "Of course, we would not expect the preservation of ancient structures made entirely of soft tissues (e.g. rods and cone cells in the retina...)." So, check this next item... :) - And... no vertebrates in the Cambrian? Well, from the journal Nature in 2014, a "Lower-Middle Cambrian... primitive fish displays unambiguous vertebrate features: a notochord, a pair of prominent camera-type eyes, paired nasal sacs, possible cranium and arcualia, W-shaped myomeres, and a post-anal tail" Primitive? - Fast-growing juvenile bone tissue, thought to appear in the Cretaceous, has been pushed back 100 million years: "This pushes the origin of fibrolamellar bone in Sauropterygia back from the Cretaceous to the early Middle Triassic..."- Trilobites "advanced" (not the predicted primitive) digestion "525 million" years ago - And there's this, a "530 million year old" fish, "50 million years before the current estimate of when fish evolved" - Mycobacterium tuberculosis 100,000 yr-old MRCA (most recent common ancestor) now 245 million- Fungus long claimed to originate 500M years ago, now found at allegedly 950 Mya (and still biological "the distant past... may have been much more 'modern' than we thought." :) - A rock contained pollen a billion years before plants evolved, according to a 2007 paper describing "remarkably preserved" fossil spores in the French Alps that had undergone high-grade metamorphism - 2.5 billion year old cyanobacteria fossils (made of organic material found in a stromatolite) appear about "200 million years before the [supposed] Great Oxidation Event". - 2.7 billion year old eukaryotes (cells with a nucleus) existed (allegedly) 1 billion years before expected - 3.5 billion year "cell division evidently identical to that of living filamentous prokaryotes." - And even older cyanobacteria! At 220 million years earlier than thought, per Nature's 3.7 billion year old dating of stromatolites! - The universe and life itself (in 2019 with the universe dated a billion, now, no, wait, two billion!, years younger than previously thought, that's not only squeezing biological but also astronomical evolution, with the overall story getting really tight) - Mantis shrimp, with its rudimentary color but advanced UV vision, is allegedly ancient. - Hadrosaur teeth, all 1400 of them, were "more complex than those of cows, horses, and other well-known modern grazers." Professor stunned by the find! (RSR predicts that, by 2030 just to put an end date on it, more fossils will be found from the geologic column that will be more "advanced" as compared to living organisms, just like this hadrosaur and like the allegedly 100M year old hagfish  fossil having more slime glands than living specimens.)  - Trace fossils "exquisitely preserved" of mobile organisms (motility) dated at 2.1 billion years ago, a full 1.5 billion earlier than previously believed - Various multicellular organisms allegedly 2.1 billion years old, show multicellularity 1.5 billion years sooner than long believed   - Pre-sauropod 26,000-pound dinosaur "shows us that even as far back as 200 million years ago, these animals had already become the largest vertebrates to ever walk the Earth." - The Evo-devo squeeze, i.e., evolutionary developmental biology, as with rsr.org/evo-devo-undermining-darwinism. - Extinct Siberian one-horned rhinos coexisted with mankind. - Whale "evolution" is being crushed in the industry-wide "big squeeze". First, geneticist claims whales evolved from hippos but paleontologists say hippos evolved tens of millions of years too late! And what's worse than that is that fossil finds continue to compress the time available for whale evolution. To not violate its own plot, the Darwinist story doesn't start animals evolving back into the sea until the cast includes land animals suitable to undertake the legendary journey. The recent excavation of whale fossils on an island of the Antarctic Peninsula further compresses the already absurdly fast 10 million years to allegedly evolve from the land back to the sea, down to as little as one million years. BioOne in 2016 reported a fossil that is "among the oldest occurrences of basilosaurids worldwide, indicating a rapid radiation and dispersal of this group since at least the early middle Eocene." By this assessment, various techniques produced various published dates. (See the evidence that falsifies the canonical whale evolution story at rsr.org/whales.) * Ancient Hierarchical Insect Society: "Thanks to some well-preserved remains, researchers now believe arthropod social structures have been around longer than anyone ever imagined. The encased specimens of ants and termites recently studied date back [allegedly] 100 million years." Also from the video about "the bubonic plague", the "disease is well known as a Middle Ages mass killer... Traces of very similar bacteria were found on [an allegedly] 20-million-year-old flea trapped in amber." And regarding "Caribbean lizards... Even though they are [allegedly] 20 million years old, the reptiles inside the golden stones were not found to differ from their contemporary counterparts in any significant way. Scientists attribute the rarity [Ha! A rarity or the rule? Check out rsr.org/stasis.] to stable ecological surroundings." * Squeezing and Rewriting Human History: Some squeezing simply makes aspects of the Darwinian story harder to maintain while other squeezing contradicts fundamental claims. So consider the following discoveries, most of which came from about a 12-month period beginning in 2017 which squeeze (and some even falsify) the Out-of-Africa model: - find two teeth and rewrite human history with allegedly 9.7 million-year-old teeth found in northern Europe (and they're like Lucy, but "three times older") - date blue eyes, when humans first sported them, to as recently as 6,000 years ago   - get mummy DNA and rewrite human history with a thousand years of ancient Egyptian mummy DNA contradicting Out-of-Africa and demonstrating Out-of-Babel - find a few footprints and rewrite human history with allegedly 5.7 million-year-old human footprints in Crete - re-date an old skull and rewrite human history with a very human skull dated at 325,000 years old and redated in the Journal of Physical Anthropology at about 260,000 years old and described in the UK's Independent, "A skull found in China [40 years ago] could re-write our entire understanding of human evolution." - date the oldest language in India, Dravidian, with 80 derivatives spoken by 214 million people, which appeared on the subcontinent only about 4,500 years ago, which means that there is no evidence for human language for nearly 99% of the time that humans were living in Asia. (Ha! See rsr.org/origin-of-language for the correct explanation.) - sequence a baby's genome and rewrite human history with a 6-week old girl buried in Alaska allegedly 11,500 years ago challenging the established history of the New World. (The family buried this baby girl just beneath their home like the practice in ancient Mesopotamia, the Hebrews who sojourned in Egypt, and in Çatalhöyük in southern Turkey, one of the world's most ancient settlements.) - or was that 130,000? years ago as the journal Nature rewrites human history with a wild date for New World site - and find a jawbone and rewrite human history with a modern looking yet allegedly 180,000-year-old jawbone from Israel which "may rewrite the early migration story of our species" by about 100,000 years, per the journal Science - re-date a primate and lose yet another "missing link" between "Lucy" and humans, as Homo naledi sheds a couple million years off its age and drops from supposedly two million years old to (still allegedly) about 250,000 years old, far too "young" to be the allegedly missing link - re-analysis of the "best candidate" for the most recent ancestor to human beings, Australopithecus sediba, turns out to be a juvenile Lucy-like ape, as Science magazine reports work presented at the American Association of Physical Anthropologists 2017 annual meeting - find skulls in Morocco and "rewrite human history" admits the journal Nature, falsifying also the "East Africa" part of the canonical story - and from the You Can't Make This Stuff Up file, NPR reports in April 2019, Ancient Bones And Teeth Found In A Philippine Cave May Rewrite Human History. :) - Meanwhile, whereas every new discovery requires the materialists to rewrite human history, no one has had to rewrite Genesis, not even once. Yet, "We're not claiming that the Bible is a science textbook. Not at all. For the textbooks have to be rewritten all the time!"  - And even this from Science: "humans mastered the art of training and controlling dogs thousands of years earlier than previously thought."- RSR's Enyart commented on the Smithsonian's 2019 article on ancient DNA possibly deconstructing old myths...  This Smithsonian article about an ancient DNA paper in Science Advances, or actually, about the misuse of such papers, was itself a misuse. The published research, Ancient DNA sheds light on the genetic origins of early Iron Age Philistines, confirmed Amos 9:7 by documenting the European origin of the biblical Philistines who came from the island of Caphtor/Crete. The mainstream media completely obscured this astounding aspect of the study but the Smithsonian actually stood the paper on its head. [See also rsr.org/archaeology.]* Also Squeezing Darwin's Theory: - Evolution happens so slowly that we can't see it, yet - it happens so fast that millions of mutations get fixed in a blink of geologic time AND: - Observing a million species annually should show us a million years of evolution, but it doesn't, yet - evolution happens so fast that the billions of "intermediary" fossils are missing AND: - Waiting for helpful random mutations to show up explains the slowness of evolution, yet - adaption to changing environments is often immediate, as with Darwin's finches Finches Adapt in 17 Years, Not 2.3 Million: Charles Darwin's finches are claimed to have taken 2,300,000 years to diversify from an initial species blown onto the Galapagos Islands. Yet individuals from a single finch species on a U.S. Bird Reservation in the Pacific were introduced to a group of small islands 300 miles away and in at most 17 years, like Darwin's finches, they had diversified their beaks, related muscles, and behavior to fill various ecological niches. So Darwin's finches could diversify in just 17 years, and after 2.3 million more years, what had they evolved into? Finches! Hear this also at rsr.org/lee-spetner and see Jean Lightner's review of the Grants' 40 Years. AND: - Fossils of modern organisms are found "earlier" and "earlier" in the geologic column, and - the "oldest" organisms are increasingly found to have anatomical, proteinaceous, prokaryotic, and eukaryotic sophistication and similarity to "modern" organisms AND: - Small populations are in danger of extinction (yet they're needed to fix mutations), whereas - large populations make it impossible for a mutation to become standard AND: - Mutations that express changes too late in an organism's development can't effect its fundamental body plan, and - mutations expressed too early in an organism's development are fatal (hence among the Enyart sayings, "Like evolving a vital organ, most major hurdles for evolutionary theory are extinction-level events.") AND: - To evolve flight, you'd get bad legs - long before you'd get good wings AND: - Most major evolutionary hurdles appear to be extinction-level events- yet somehow even *vital* organs evolve (for many species, that includes reproductive organs, skin, brain, heart, circulatory system, kidney, liver, pancreas, stomach, small intestines, large intestines, lungs -- which are only a part of the complex respiration system) AND: - Natural selection of randomly taller, swifter, etc., fish, mammals, etc. explains evolution yet - development of microscopic molecular machines, feedback mechanisms, etc., which power biology would be oblivous to what's happening in Darwin's macro environment of the entire organism AND: - Neo-Darwinism suggests genetic mutation as the engine of evolution yet - the there is not even a hypothesis for modifying the vast non-genetic information in every living cell including the sugar code, electrical code, the spatial (geometric) code, and the epigenetic code AND: - Constant appeals to "convergent" evolution (repeatedly arising vision, echolocation, warm-bloodedness, etc.) - undermine most Darwinian anatomical classification especially those based on trivialities like odd or even-toed ungulates, etc. AND: - Claims that given a single species arising by abiogenesis, then - Darwinism can explain the diversification of life, ignores the science of ecology and the (often redundant) biological services that species rely upon AND: - humans' vastly superior intelligence indicates, as bragged about for decades by Darwinists, that ape hominids should have the greatest animal intelligence, except that - many so-called "primitive" creatures and those far distant on Darwin's tee of life, exhibit extraordinary rsr.org/animal-intelligence even to processing stimuli that some groups of apes cannot AND: - Claims that the tree of life emerges from a single (or a few) common ancestors - conflict with the discoveries of multiple genetic codes and of thousands of orphan genes that have no similarity (homology) to any other known genes AND (as in the New Scientist cover story, "Darwin Was Wrong about the tree of life", etc.): - DNA sequences have contradicted anatomy-based ancestry claims - Fossil-based ancestry claims have been contradicted by RNA claims - DNA-based ancestry claims have been contradicted by anatomy claims - Protein-based ancestry claims have been contradicted by fossil claims. - And the reverse problem compared to a squeeze. Like finding the largest mall in America built to house just a kid's lemonade stand, see rsr.org/200 for the astounding lack of genetic diversity in humans, plants, and animals, so much so that it could all be accounted for in just about 200 generations! - The multiplied things that evolved multiple times - Etc. * List of Ways Darwinists Invent their Tree of Life, aka Pop Goes the Weasle – Head and Shoulders, Knees and Toes: Evolutionists change their selection of what evidence they use to show 'lineage', from DNA to fossils to genes to body plans to teeth to many specific anatomical features to proteins to behavior to developmental similarities to habitat to RNA, etc. and to a combination of such. Darwinism is an entire endeavor based on selection bias, a kind of logical fallacy. By anti-science they arbitrarily select evidence that best matches whichever evolutionary story is currently preferred." -Bob E. The methodology used to create the family tree edifice to show evolutionary relationships classifies the descent of organisms based on such attributes as odd-toed and even-toed ungulates. Really? If something as wildly sophisticated as vision allegedly evolved multiple times (a dozen or more), then for cryin' out loud, why couldn't something as relatively simple as odd or even toes repeatedly evolve? How about dinosaur's evolving eggs with hard shells? Turns out that "hard-shelled eggs evolved at least three times independently in dinosaurs" (Nature, 2020). However, whether a genus has an odd or even number of toes, and similar distinctions, form the basis for the 150-year-old Darwinist methodology. Yet its leading proponents still haven't acknowledged that their tree building is arbitrary and invalid. Darwin's tree recently fell anyway, and regardless, it has been known to be even theoretically invalid all these many decades. Consider also bipedalism? In their false paradigm, couldn't that evolve twice? How about vertebrate and non-vertebrates, for that matter, evolving multiple times? Etc., etc., etc. Darwinists determine evolutionary family-tree taxonomic relationships based on numbers of toes, when desired, or on hips (distinguishing, for example, dinosaur orders, until they didn't) or limb bones, or feathers, or genes, or fossil sequence, or neck bone, or..., or..., or... Etc. So the platypus, for example, can be described as evolving from pretty much whatever story would be in vogue at the moment...   * "Ancient" Protein as Advanced as Modern Protein: A book review in the journal Science states, "the major conclusion is reached that 'analyses made of the oldest fossils thus far studied do not suggest that their [allegedly 145-million year-old] proteins were chemically any simpler than those now being produced.'" 1972, Biochemistry of Animal Fossils, p. 125 * "Ancient" Lampreys Just Modern Lampreys with Decomposed Brain and Mouth Parts: Ha! Researches spent half-a-year documenting how fish decay. RSR is so glad they did! One of the lessons learned? "[C]ertain parts of the brain and the mouth that distinguish the animals from earlier relatives begin a rapid decay within 24 hours..." :) * 140-million Year Old Spider Web: The BBC and National Geographic report on a 140-million year old spider web in amber which, as young-earth creationists expect, shows threads that resemble silk spun by modern spiders. Evolutionary scientists on the otherhand express surprise "that spider webs have stayed the same for 140 million years." And see the BBC. * Highly-Credentialed Though Non-Paleontologist on Flowers: Dr. Harry Levin who spent the last 15 years of a brilliant career researching paleontology presents much evidence that flowering plants had to originate not 150 million years ago but more than 300 million years ago. (To convert that to an actual historical timeframe, the evidence indicates flowers must have existed prior to the time that the strata, which is popularly dated to 300 mya, actually formed.) * Rampant Convergence: Ubiquitous appeals to "convergent" evolution (vision, echolocation, warm-bloodedness, icthyosaur/dolphin anatomy, etc.), all allegedly evolving multiple times, undermines anatomical classification based on trivialities like odd or even-toed ungulates, etc. * Astronomy's Big Evolution Squeeze: - Universe a billion, wait, two billion, years younger than thought   (so now it has to evolve even more impossibly rapidly) - Sun's evolution squeezes biological evolution - Galaxies evolving too quickly - Dust evolving too quickly - Black holes evolving too quickly - Clusters of galaxies evolving too quickly. * The Sun's Evolution Squeezes Life's Evolution: The earlier evolutionists claim that life began on Earth, the more trouble they have with astrophysicists. Why? They claim that a few billion years ago the Sun would have been far more unstable and cooler. The journal Nature reports that the Faint young Sun paradox remains for the "Sun was fainter when the Earth was young, but the climate was generally at least as warm as today". Further, our star would shoot out radioactive waves many of which being violent enough to blow out Earth's atmosphere into space, leaving Earth dead and dry like Mars without an atmosphere. And ignoring the fact that powerful computer simulators cannot validate the nebula theory of star formation, if the Sun had formed from a condensing gas cloud, a billion years later it still would have been emitting far less energy, even 30% less, than it does today. Forget about the claimed one-degree increase in the planet's temperature from man-made global warming, back when Darwinists imagine life arose, by this just-so story of life spontaneously generating in a warm pond somewhere (which itself is impossible), the Earth would have been an ice ball, with an average temperature of four degrees Fahrenheit below freezing! See also CMI's video download The Young Sun. * Zircons Freeze in Molten Eon Squeezing Earth's Evolution? Zircons "dated" 4 to 4.4 billion years old would have had to freeze (form) when the Earth allegedly was in its Hadean (Hades) Eon and still molten. Geophysicist Frank Stacey (Cambridge fellow, etc.) has suggested they may have formed above ocean trenches where it would be coolest. One problem is that even further squeezes the theory of plate tectonics requiring it to operate two billion years before otherwise claimed. A second problem (for these zircons and the plate tectonics theory itself) is that ancient trenches (now filled with sediments; others raised up above sea level; etc.) have never been found. A third problem is that these zircons contain low isotope ratios of carbon-13 to carbon-12 which evolutionists may try to explain as evidence for life existing even a half-billion years before they otherwise claim. For more about this (and to understand how these zircons actually did form) just click and then search (ctrl-f) for: zircon character. * Evolution Squeezes Life to Evolve with Super Radioactivity: Radioactivity today breaks chromosomes and produces neutral, harmful, and fatal birth defects. Dr. Walt Brown reports that, "A 160-pound person experiences 2,500 carbon-14 disintegrations each second", with about 10 disintergrations per second in our DNA. Worse for evolutionists is that, "Potassium-40 is the most abundant radioactive substance in... every living thing." Yet the percentage of Potassium that was radioactive in the past would have been far in excess of its percent today. (All this is somewhat akin to screws in complex machines changing into nails.) So life would have had to arise from inanimate matter (an impossibility of course) when it would have been far more radioactive than today. * Evolution of Uranium Squeezed by Contrasting Constraints: Uranium's two most abundant isotopes have a highly predictable ratio with 235U/238U equaling 0.007257 with a standard deviation of only 0.000017. Big bang advocates claim that these isotopes formed in distant stellar cataclysms. Yet that these isotopes somehow collected in innumerable small ore bodies in a fixed ratio is absurd. The impossibility of the "big bang" explanation of the uniformity of the uranium ratio (rsr.org/bb#ratio) simultaneously contrasts in the most shocking way with its opposite impossibility of the missing uniform distribution of radioactivity (see rsr.org/bb#distribution) with 90% of Earth's radioactivity in the Earth's crust, actually, the continental crust, and even at that, preferentially near granite! A stellar-cataclysmic explanation within the big bang paradigm for the origin of uranium is severely squeezed into being falsified by these contrasting constraints. * Remarkable Sponges? Yes, But For What Reason? Study co-author Dr. Kenneth S. Kosik, the Harriman Professor of Neuroscience at UC Santa Barbara said, "Remarkably, the sponge genome now reveals that, along the way toward the emergence of animals, genes for an entire network of many specialized cells evolved and laid the basis for the core gene logic of organisms that no longer functioned as single cells." And then there's this: these simplest of creatures have manufacturing capabilities that far exceed our own, as Degnan says, "Sponges produce an amazing array of chemicals of direct interest to the pharmaceutical industry. They also biofabricate silica fibers directly from seawater in an environmentally benign manner, which is of great interest in communications [i.e., fiber optics]. With the genome in hand, we can decipher the methods used by these simple animals to produce materials that far exceed our current engineering and chemistry capabilities." Kangaroo Flashback: From our RSR Darwin's Other Shoe program: The director of Australia's Kangaroo Genomics Centre, Jenny Graves, that "There [are] great chunks of the human genome… sitting right there in the kangaroo genome." And the 20,000 genes in the kangaroo (roughly the same number as in humans) are "largely the same" as in people, and Graves adds, "a lot of them are in the same order!" CMI's Creation editors add that "unlike chimps, kangaroos are not supposed to be our 'close relatives.'" And "Organisms as diverse as leeches and lawyers are 'built' using the same developmental genes." So Darwinists were wrong to use that kind of genetic similarity as evidence of a developmental pathway from apes to humans. Hibernating Turtles: Question to the evolutionist: What happened to the first turtles that fell asleep hibernating underwater? SHOW UPDATE Of Mice and Men: Whereas evolutionists used a very superficial claim of chimpanzee and human genetic similarity as evidence of a close relationship, mice and men are pretty close also. From the Human Genome Project, How closely related are mice and humans?, "Mice and humans (indeed, most or all mammals including dogs, cats, rabbits, monkeys, and apes) have roughly the same number of nucleotides in their genomes -- about 3 billion base pairs. This comparable DNA content implies that all mammals [RSR: like roundworms :)] contain more or less the same number of genes, and indeed our work and the work of many others have provided evidence to confirm that notion. I know of only a few cases in which no mouse counterpart can be found for a particular human gene, and for the most part we see essentially a one-to-one correspondence between genes in the two species." * Related RSR Reports: See our reports on the fascinating DNA sequencing results from roundworms and the chimpanzee's Y chromosome! * Genetic Bottleneck, etc: Here's an excerpt from rsr.org/why-was-canaan-cursed... A prediction about the worldwide distribution of human genetic sequencing (see below) is an outgrowth of the Bible study at that same link (aka rsr.org/canaan), in that scientists will discover a genetic pattern resulting from not three but four sons of Noah's wife. Relevant information comes also from mitochondrial DNA (mtDNA) which is not part of any of our 46 chromosomes but resides outside of the nucleus. Consider first some genetic information about Jews and Arabs, Jewish priests, Eve, and Noah. Jews and Arabs Biblical Ancestry: Dr. Jonathan Sarfati quotes the director of the Human Genetics Program at New York University School of Medicine, Dr. Harry Ostrer, who in 2000 said: Jews and Arabs are all really children of Abraham … And all have preserved their Middle Eastern genetic roots over 4,000 years. This familiar pattern, of the latest science corroborating biblical history, continues in Dr. Sarfati's article, Genesis correctly predicts Y-Chromosome pattern: Jews and Arabs shown to be descendants of one man. Jewish Priests Share Genetic Marker: The journal Nature in its scientific correspondence published, Y Chromosomes of Jewish Priests, by scie

South East Technological University (SETU) is thrilled to announce its role in the ambitious EVEREST project. Led by the University College Dublin (UCD), the project is a collaboration of 21 institutions from 11 countries, focused on harnessing the potential of extracellular vesicles (EVs) to transform biomedical research. With a €1.3 million budget funded through the prestigious Marie Sklodowska-Curie Actions (MSCA) programme under Horizon Europe, the project will commence in January 2025 and continue over a four-year period. Extracellular vesicles are small, cell-derived particles that serve as messengers between cells, carrying proteins, lipids, and nucleic acids essential for intercellular communication. By standardising methods for isolating and characterising these vesicles, EVEREST aims to leverage their potential for non-invasive diagnostics and personalised treatments, enabling more precise and effective interventions for complex diseases such as cancer and cardiovascular conditions. Prof Marie Claire Van Hout, Vice President for Research, Innovation and Impact at SETU, highlighted the significance of the project for the university: "The EVEREST project exemplifies SETU's commitment to advancing impactful research that can improve lives globally. Through collaboration with leading institutions and industry partners, we are contributing to innovative biomedical solutions that hold the potential to change the landscape of diagnostics and treatment. This is an exciting opportunity to showcase SETU's research capacity on an international stage." SETU's Ocular Therapeutics Research Group (OTRG), led by Dr Laurence Fitzhenry, is excited to contribute to this interdisciplinary initiative. Reflecting on the project, Dr Fitzhenry shared, "EVEREST provides a platform for researchers to develop valuable scientific skills while actively advancing transformative treatment options for those affected by challenging diseases. Our team is looking forward to expanding our expertise and collaborating with a consortium that spans multiple disciplines and industries." The EVEREST consortium unites leading academic and non-academic partners, with academic collaborators including University College Dublin, Trinity College Dublin, and Queen's University Belfast, among others across Europe. Industry partners such as SiriusXT, Bioreperia, and Fox Biosystems bring critical commercial perspectives, ensuring a robust approach from fundamental research to practical applications. Prof Breandan Kennedy and Dr Yolanda Alvarez, project leaders with significant experience managing European projects like CRYSTAL3 and 3D-NEO-NET, will ensure the project's effective progress. EVEREST will benefit greatly from the MSCA Staff Exchange programme, which promotes international collaboration, knowledge transfer, and innovation, with the goal of generating solutions to some of healthcare's most pressing global challenges. Through EVEREST, SETU and its partners are set to push the boundaries of biomedical science, leveraging extracellular vesicles to advance early diagnostics and pave the way for future treatment breakthroughs. More about Irish Tech News Irish Tech News are Ireland's No. 1 Online Tech Publication and often Ireland's No.1 Tech Podcast too. You can find hundreds of fantastic previous episodes and subscribe using whatever platform you like via our Anchor.fm page here: https://anchor.fm/irish-tech-news If you'd like to be featured in an upcoming Podcast email us at Simon@IrishTechNews.ie now to discuss. Irish Tech News have a range of services available to help promote your business. Why not drop us a line at Info@IrishTechNews.ie now to find out more about how we can help you reach our audience. You can also find and follow us on Twitter, LinkedIn, Facebook, Instagram, TikTok and Snapchat.

Happy Hour 首次迎來代班主持人，在Mike回來跟我們聊AI之前，先由Angel代班跟若晴一起聊天陪大家度過無聊時光啦！你的生命中、職涯中有沒有很重要的貴人呢？讓我們跟大家分享一下我們的超級貴人，謝謝老師們在我們生涯上的幫助❤️ 也歡迎聽眾跟我們分享你生命中的貴人喔！ 節目內容 我們算是influencer了嗎？！ 訪問真網紅阿淇博士的集數大家聽了嗎？ 期待在TAAB和SoCal TBA見到大家！ 諾貝爾獎AI大獲全勝，大家有猜對幾個嗎？ 若晴又遇上裁員…在另一邊的感觸 希望生技寒冬快快過去 楊嘉鈴老師真的是很暖心的教育家 結論其實是清大生科充滿我們的貴人 Angel各個時期的貴人 若晴命很好總是遇到好老闆 -- Hosting provided by SoundOn

In this episode of Wistar Science Up Close, Dr. Maureen Murphy gets insights from Wistar postdoctoral student, Dr. Ebony Gary and first year Ph.D. cancer biology student Tyler Yang about life in and outside of the lab. Hear firsthand how they balance a career in biomedical research and their life outside the lab.

Send us a textAndrew Koutnik, PhD is a researcher studying the influence of nutrition and metabolism on health, disease, and performance. He originally began his research path at Florida State University in the Exercise Science studying the influence of nutrition, exercise, supplementation, and environmental extremes on health-based outcomes in normal and clinical populations.From Florida State University, he transitioned into Biomedical Research where he received his doctorate in Biomedical Sciences with the Metabolic Medicine Lab at University of South Florida Morsani College of Medicine with a focus on studying metabolism and metabolic therapies for health, disease, and performance outcomes.Personally, Andrew Koutnik also uses exercise, nutrition, and lifestyle factors to manage Type-1 Diabetes for over 12 years. Type-1 Diabetes has and continues to give an incredible in-depth personal journey into the world of our metabolism, how it works, how day-to-day life (sometimes moment-by-moment choices) influences it, and how these changes on metabolism can have far reaching effects over other aspects of our physiology.This combination of researching nutrition and exercise, but also dealing with its benefits and consequences daily as a Type-1 Diabetic, created a strong appreciation for the metabolic role nutrition and lifestyle can play into disease prevention and management.Andrew is currently involved in ongoing research projects exploring how metabolism influences and is influenced by health, disease, and performance, and how we might leverage lifestyle and medical tools to influences these same categories.Find Dr. Andrew Koutnik at-https://www.andrewkoutnik.com/TW- @AKoutnikIG- @andrewkoutnikphdFind Boundless Body at- myboundlessbody.com Book a session with us here!

Dr. Claire Pomeroy is a distinguished physician, educator, and advocate for healthcare reform. With an undergraduate and medical degree from the University of Michigan and an MBA from the University of Kentucky, Dr. Pomeroy has served on the medical faculties of the University of Kentucky, the University of Minnesota, and UC Davis, where she became the dean of the School of Medicine and is now professor emeritus. Her career has focused on addressing healthcare disparities, advocating for a proactive, preventative healthcare system that ensures equitable care for all populations, especially the underserved. Since June 2013, Dr. Pomeroy has been the president of the Albert and Mary Lasker Foundation, where she provides strategic leadership in promoting medical research and public advocacy. The Lasker Foundation is renowned for its prestigious annual awards that recognize groundbreaking achievements in medical science and public service. Under her leadership, the foundation continues to inspire scientific innovation and discovery worldwide. Her life experiences, including overcoming a difficult childhood in the foster care system, have shaped her deep commitment to healthcare equality and compassion for disadvantaged populations. Dr. Pomeroy's unique blend of scientific expertise, leadership, and advocacy continues to impact the field of medical research and healthcare reform.  

三腳貓新手村總算開始講到美國博班的申請準備了！三腳貓們之前是怎麼樣長期的去規劃及準備自己的留學文件呢？來聽聽Angel、若晴及雯薇的經驗吧！ 留學文件有哪些 出國留學的起心動念 準備的時間點 耕耘自己的強項！自己的亮點 選校策略 設定止損點 新手們的大哉問：該找留學代辦嗎 結尾：follow your heart！ 工作人員 內容製作：雯薇、若晴、Angel 後製：雯薇 文案：雯薇 音樂：雯薇 封面：雯薇 上架：雯薇 宣傳：Angel、雯薇 -- Hosting provided by SoundOn

Erin Sharoni joins Ethics Talk to discuss her article: “Which Concepts Are Key to Transitioning From Nonhuman Animal Models to Engineered Microphysiological Systems in Biomedical Research?”  Recorded April 30, 2024.  Read the full article for free at JournalOfEthics.org

Dr Aysha Akhtar joins Ethics Talk to discuss her article: “With What Should We Replace Nonhuman Animals in Biomedical Research Protocols?”  Recorded April 30, 2024.  Read the full article for free at JournalOfEthics.org

終於要來跟大家聊聊之前講了又講說要錄的自體免疫疾病的細胞治療啦！究竟為什麼許多細胞之聊公司都紛紛把目標從癌症轉往自體免疫疾病？細胞治療可以如何應用在影響全世界將近10%人口的自體免疫疾病上？當昂貴的治療不是關乎生死，而是一輩子的生活品質，又可能會遇到哪些議題和挑戰？CAAR-T 跟 CAR-Treg又是什麼酷東西呢？一起來聽聽這一集吧！ 節目內容： Happy Hour 一週年啦！ Heat wave 熱爆… 選擇戰場也是很重要的軟實力 CAR-T複習 自體免疫疾病簡介 所以CAR-T為什麼可以治療自體免疫疾病？ 不是關乎生死而是生活品質的抉擇 酷酷的CAAR-T跟CAR-Treg -- Hosting provided by SoundOn

1966 冬天一篇 John W. Saunders Jr. 對雞胚胎細胞大規模死亡的描述，在經過超過半個世紀後， 又在另一群科學家心中激起新的一波漣漪。於是，隨著一篇在 2024 年夏天發表在《自然》上關於死亡波的文章，總算讓大家了解到死亡可以像波一般的傳遞。今天，三腳貓實驗室邀請到中研院陳昇宏老師，聊聊他的研究經歷以及研究。讓我們一窺，他的團隊為什麼能在這六年來對未知追尋中，找到六十年前對細胞大規模死亡描述的證據，以及背後的分子機制。 相關連結 https://celldynamicslabchinese.mystrikingly.com/blog/af75ad58088? https://www.nature.com/articles/s41586-024-07623-6 https://www.nature.com/articles/d41586-024-02125-x? https://www.facebook.com/story.php?story_fbid=797014859287789&id=100069378452298&rdid=ap7BXY4pc7g4v4Dh https://investigator.tw/4142/陳昇宏老師專訪│中央研究院分子生物研究所/ 工作人員 內容製作：浩文、陳昇宏 後製：浩文 文案：浩文 音樂：雯薇 封面：雯薇 上架：浩文 宣傳：Angel、雯薇 -- Hosting provided by SoundOn

接續著之前裁員的題目，Mike跟若晴在這集各自討論了他們怎麼看履歷怎麼寫。履歷真的得這樣寫嗎？海投有用嗎？ 來聽聽他們不藏私的看法吧！連結附上兩則若晴分享的新聞以及兩種面試以及履歷撰寫上常見的敘述方式。 連結 若晴分享的兩則新聞： In vivo CAR-T from Umoja got IND: https://www.umoja-biopharma.com/news/umoja-biopharma-announces-fda-clearance-of-ind-application-for-ub-vv111-a-cd19-directed-in-situ-car-t-for-hematologic-malignancies/ First TCR-T FDA accelerated approval: https://www.adaptimmune.com/investors-and-media/news-center/press-releases/detail/271/adaptimmune-receives-u-s-fda-accelerated-approval-of Mike提到的履歷撰寫法： X-Y-Z敘述法：https://youtu.be/Tt08KmFfIYQ?si=68xpz9pWCMFPg9bx&t=323 STAR方法：https://www.indeed.com/career-advice/resumes-cover-letters/star-method-resume 節目內容 感謝聽眾分享兩人取暖 新聞時間（一）：In Vivo CAR-T進入臨床實驗 新聞時間（二）T-cell Receptor Therapy TECELRA 拿到FDA許可 履歷更上一層樓的自我拷問 怎麼看海投這件事 兩人履歷上究竟寫了什麼？ 設定好人設是重要的第一步 精鍊、精鍊、再精鍊 X-Y-Z敘述法 其實有經驗的hiring manager都看得出來啦… -- Hosting provided by SoundOn

Could overcoming addiction be as simple as taking a pill?And what if psychedelics could be our gateway into healing mental health and obesity struggles?Today's conversation is nothing short of fascinating.Join me and special guest Mark Haden and Adi Zuloff-Shani from Clearmind Medicine as we dive deep into the current landscape of psychedelics in the health and wellness space.They share about an incredible new molecule that is currently starting clinical trials and showing promising lasting effects on addiction, depression and obesity.Mark Haden Mark Haden is a trailblazer in the field of psychedelic medicine, currently serving as Director of Clinical Research at Psygen and Adjunct Professor at the University of British Columbia School of Population and Public Health. He was a co-founder and spent 10 years as Executive Director of the renowned Multidisciplinary Association for Psychedelic Studies Canada (MAPS). Haden has dedicated the last 30 years to public education and training on drugs and drug policy, including advising the Health Officers Council of British Columbia on the issues of a regulated market for all currently illegal drugs as well as working with Addiction Services in counselling and supervisory roles. He is a frequent keynote speaker and distinguished author on the issues of drug control policy and psychedelics and was awarded the Queen's Diamond Jubilee Medal for his work on drug policy reform in 2013.Adi Zuloff-Shani, PhD Chief Executive Officer at Clearmind MedicineDr. Adi Zuloff-Shani is a Biomedical Research and Development Executive with a vast experience with over 20 years of strategic and operational leadership in the healthcare industry and a deep understanding of therapeutics development in heavily regulated environments. She has expertise in the Pharmaceutical industry, leading cell and drug development through drug and product development, CMC, non-clinical, all stages of clinical development, as well as clinical development strategies and regulatory (FDA, EMEA, others) interactions, NDAs, leading INDs, as well as parallel EU activities. Dr. Zuloff-Shani holds a Ph.D. in human biology and immunology from Bar-Ilan University, Israel.******************Connect with Clearmind Medicine Team:Facebook: https://www.facebook.com/ClearmindMedicine Twitter: https://twitter.com/ClearmindCMND YouTube: https://www.youtube.com/channel/UCg_JDmUZSqstavsbd3zYmmg Instagram: https://www.instagram.com/clearmindmed/ LinkedIn: https://ca.linkedin.com/company/clearmind-medicine ******************➠ Discover the unique ROOT CAUSE that is keeping you stuck on the sugar rollercoaster every year. Take the QUIZ HERE NOW. ➠ Ready to finally kick your emotional eating habit and build a new healthy relationship with sugar from the inside out? Say goodbye to late night snacking and stress eating for good. Get immediate access to my exclusive and FREE Kick Emotional Eating 3 Part Training here. ➠  Want to stay connected and work with Dani during her year off? Come join us in the Sugar Freedom Collective Monthly Community HERE.   ******************Come hang out with me and keep the conversation going on social media:Instagram: https://www.instagram.com/danielleda

Can everyone learn to lead? Roy Bethge - a successful #leader - anchors his answer in an early #failure. What happened next changed his course and shaped how he views #leadership, #relationships, and #career. Listen now Rate this episode in Spotify (Remember!) Follow Share with friends! Curious about the #Leaderly app? Follow us on LinkedIn and check out our website. More about Roy Currently Director of Security at Hard Rock Casino in Rockford, Illinois 34-year police career Previous Chief of Police in Cherry Valley, IL Trainer with expertise in #leaderdevelopment, active shooter response, use of force, and adult learning Lead instructor & course developer for Louisiana State University's National Center for Biomedical Research and Training Lives in the Rockford area with his wife Judy and their boys

微軟在智慧醫療領域下好大一盤棋？最近釋出的foundation model目標何在？這跟上次講的權重又有何關係？真是項莊舞劍，意在沛公？ 連結： Forbes: https://www.forbes.com/sites/saibala/2024/05/22/microsoft-announces-new-foundation-model-for-digital-pathology-diving-deeper-into-clinical-medicine/ Multimodal Generative AI: the Next Frontier in Precision Health by Hoifung Poon: https://www.youtube.com/watch?v=CGyQxdM2KU8 節目內容： 若晴有要事要更正 Inside Out 2不能暴雷的討論 前情提要，權重是啥？ 對醫療AI的想像 微軟新發布的模型 Foundation model 玻片數位化 醫療填空題 最終的目標是？？？ -- Hosting provided by SoundOn

若晴被裁員後的故事第二集來啦！一起來聽聽她如何在突如其來的裁員後，打起精神重整旗鼓找工作，運用前同事的connections迅速的在兩週內跟多位hiring managers講到電話，在一個月內完成面試拿到工作。希望這兩集若晴n=1的故事能幫大家稍微揭開裁員的神秘面紗。 節目內容 怎樣的角色可以避免被裁員？ 用現實的焦慮把自己從低潮難過中拉出來 Day -1 開始改履歷跟寫cover letter 前同事紛紛主動伸出援手幫忙遞履歷 裁員兩週內就跟三位hiring managers講到電話拿到面試 只有一個機會就抓住這個機會 人品好牌品就好？！ 前老闆義氣相挺 LA 細胞治療圈超小 五週內順利拿到正式offer 原來connections這麼好用！ 被裁員不是丟臉的事 不要用封面評斷一本書 -- Hosting provided by SoundOn

Wanna chat about the episode? Or just hang out? Come join us on discord!   --- How could I enjoy a yacht if I know we're all going to die and disappear? - Bill Faloon   Chris & Kayla head back to Church to learn more about the man behind the curtain. --- *Search Categories* Anthropological; Science / Pseudoscience; Common interest / Fandom   --- *Topic Spoiler* Bill Faloon & The Church of Perpetual Life   --- Further Reading https://www.churchofperpetuallife.org/ https://www.youtube.com/@COPL18/featured https://en.wikipedia.org/wiki/William_Faloon https://en.wikipedia.org/wiki/Biomedical_Research_%26_Longevity_Society https://www.orlandosentinel.com/1993/01/31/the-big-chill-7/ https://www.yahoo.com/news/society-gala-used-sell-young-093510021.html https://www.vice.com/en/article/9a3kwe/the-church-of-perpetual-life https://www.popsci.com/forever-man-immortality-science/ https://www.browardpalmbeach.com/news/bill-faloon-and-saul-kent-major-figures-in-cryonics-movement-start-a-church-in-hollywood-6969096 https://www.miaminewtimes.com/news/south-florida-church-pursues-eternal-life-through-cryonics-inflaming-critics-and-the-irs-7608632 Bill Faloon: A Life Long Quest To Reverse Human Aging! --- *Patreon Credits* Michaela Evans, Heather Aunspach, Alyssa Ottum, David Whiteside, Jade A, amy sarah marshall, Martina Dobson, Eillie Anzilotti, Lewis Brown, Kelly Smith Upton, Wild Hunt Alex, Niklas Brock, Jim Fingal Jenny Lamb, Matthew Walden, Rebecca Kirsch, Pam Westergard, Ryan Quinn, Paul Sweeney, Erin Bratu, Liz T, Lianne Cole, Samantha Bayliff, Katie Larimer, Fio H, Jessica Senk, Proper Gander, Nancy Carlson, Carly Westergard-Dobson, banana, Megan Blackburn, Instantly Joy, Athena of CaveSystem, John Grelish, Rose Kerchinske, Annika Ramen, Alicia Smith, Kevin, Velm, Dan Malmud, tiny, Dom, Tribe Label - Panda - Austin, Noelle Hoover, Tesa Hamilton, Nicole Carter, Paige, Brian Lancaster, tiny, GD, Elloe

生醫界Podcast扛壩子生技來一刻的主持人來作客啦！這次三腳貓邀請到任職CVS Health的資深產品研發經理劉駿來出外景。這集上半場我們聊了他在工作上，是如何用資料科學協助CVS的商業決策。他也跟我們分享了當初他是如何在博士畢業後，經過申請Insight Fellow Program，進入資料科學的商用領域。下半場劉駿很大方的跟我們分享了生技來一刻的製作經驗，以及主持人們的內心小劇場。喜歡生技來一刻的聽眾們千萬不要錯過這一集！ 另外三腳貓也趁這個機會幫BTBA宣傳即將到來的年會。這次年會主題有Antibody Drug Conjugate (ADC)、Business Development、Advanced Bioprocessing、Entrepreneurship以及Translation Science。活動第一日中午以及第二日早上，分別有職涯診斷午餐會及早餐會的networking活動，可根據午餐會房間的主題以及早餐會講者的領域分別進行交流與討論。歡迎想要拓展自己的生技和藥廠的人脈或是增進自己的職場軟技能來共襄盛舉。 年會網站：https://www.btbatw.org/2024/ 報名連結：http://www.tickettailor.com/events/btba/1264921 工作人員 內容製作：若晴、Mike、劉駿 後製：若晴、Mike 文案：若晴、Mike 音樂：雯薇 封面：雯薇 上架：Mike 宣傳：Angel、雯薇 -- Hosting provided by SoundOn

EPISODE SUMMARY Join scientist and mindset & high-performance coach Claudia Garbutt and neuroscientist Dr. Mohita Shrivastava as they talk about keeping the brain & mind healthy.   In this episode, we talk about: - Debunking common myths about the brain & mind - Daily routines to improve cognition & mental performance - Brain exercises & neurofeedback training     EPISODE NOTES Dr. MohitaShrivastava, Founder & CEO, “Cognitome LLC” is a Neuroscientist. She holds a Ph.D. degree in the field of Neurosciences from Neurosciences Centre, AIIMS, New Delhi, India & pursued part of her Ph.D research training from Kansas University Medical Centre, Kansas, USA She holds two master's degrees one in Biomedical Sciences from Dr, BR Ambedkar Centre for Biomedical Research, University of Delhi and other in Applied Clinical Psychology from Annamalai University.   She also holds an Advanced PG Diploma in Applied Neuropsychology from University of Bristol, United Kingdom. She has also completed a refresher skill enhancement training on “FMRI in Neuroscience Research” organized by MGH Athinuola Martino's Centre for Brain Imaging in collaboration with Harvard University, MIT, Massachusetts, Boston, USA.   She has completed her didactic training in EEG/QEEG conducted by STS Inc. United States, in the process of QEEG certification by International Quantitative EEG Board, USA. She has also completed phase 2 practicum training and also completed the necessary requirements for mentorship in EEG/QEEG from Successful Practitioner and InMindOut, San Antonio, Texas, USA. She has also completed her didactic training and phase 2 practicum training in Neurofeed back from Successful Practitioner and InMindOut, San Antonio, Texas, USA. She has been involved in Neuroscience and Neuropsychology teaching, research, therapeutics, projects & outreach, cognitive rehabilitation & executive functions training, Online talks/workshops for more than 12 years.   She has published various peer reviewed articles in internationally acclaimed journals, newspapers, & magazines. She writes a column on mental health in leading daily's & magazines of GCC region.   As a trained and experienced neuroscientist, she believes that brain & mind health can be improved significantly by following a holistic approach along with evidence based scientific mind and brain exercises.   She, therefore, felt the need to develop a neuroscientific, holistic, structured & customized program, ‘The Cognitome Program' to help people who are dealing with psychological, neurological, age related cognitive decline by improving cognitive functioning & their overall quality of life. Cognitome offers therapeutics/management of cognitive control & executive functions; issues of brain-mind; cognitive skills training; neuroscientific mindfulness techniques, outreach & research, awareness talks & sessions.   -------------     Special THANKS to the episode sponsor BiOptimizer!   Are you sure you're getting the RIGHT amount of the RIGHT forms of magnesium to support your mental & physical health?   Check out the BiOptimizer Magnesium Breakthrough which combines 7 of the most bio-available forms of magnesium & get a 10% discount with my special code:   Go to bioptimizers.com/claudia   and use code claudia10 at checkout to claim your 10% discount.   -------------   Links:         www.cognitomeprogram.me www.linkedin.com/in/dr-mohita-shrivastava   LinkedIn: Company Page: Cognitome LLC Twitter: Cognitome LLC @Cognitome11     Articles:   1) https://www.khaleejtimes.com/lifestyle/mental-health/21-ways-to-manage-stress-at-work 2)https://www.khaleejtimes.com/lifestyle/mental-health/mental-health-how-to-protect-oneself-against-gaslighting 3) https://www.khaleejtimes.com/lifestyle/mental-health/how-to-navigate-brain-fog-at-work 4)https://www.khaleejtimes.com/lifestyle/wellness/heres-why-multitasking-may-not-be-good-for-your-cognitive-health 5)https://www.khaleejtimes.com/lifestyle/mental-health/fear-getting-fired-from-the-job-heres-how-you-can-tackle-it 6)https://www.khaleejtimes.com/lifestyle/wellness/10-exercises-to-boost-cognitive-health 7)https://www.khaleejtimes.com/lifestyle/mental-health/what-toxic-positivity-can-do-to-you-and-how-to-tackle-it     ------------ Click this link to listen on your favorite podcast player and if you enjoy the show, please leave a rating & review: https://linktr.ee/wiredforsuccess   Help me keep this show running and awesome: Hit subscribe and join the tribe! THANK YOU for your support! 

為了想聊一篇新聞而不能不講的深度學習，打開來看裡面到底是什麼？說很複雜有多複雜？到～～底～～為什麼可以跟申請大學扯上關係咧？ 連結 3Blue1Brown: https://www.youtube.com/@3blue1brown StatQuest: https://www.youtube.com/@statquest 節目內容 上一集才剛錄音完沒什麼可以update的啦 台灣的新聞轟炸跟夜市吃什麼 科技公司在智慧醫療的野望 複習 人工神經網路為什麼叫神經網路 權重、權重、權重 在好幾個輪迴中更新的權重 塞越多圈圈就變深度學習了（？） 為什麼權重很重要下次再聊。 -- Hosting provided by SoundOn

Jonathan Long is a biochemist who studies the chemicals produced during exercise. In Long's world, “you always start with molecules,” which offer “clean handles” to understanding complex processes. His lab has identified a chemical produced in the digestive tract during exercise that can make a person stop eating. Long now studies this “gut-brain axis” for ways to treat obesity, diabetes, and, perhaps, even age-related conditions like dementia, as he tells host Russ Altman on this episode of Stanford Engineering's The Future of Everything podcast.Episode Reference Links:Stanford Profile: Jonathan Z. LongJonathan's Lab: LongLab@StanfordStudy on Endocannabinoids and Exercise Motivation: The Endocannabinoid System and Physical ExerciseConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads or Twitter/XConnect with School of Engineering >>> Twitter/XChapters:(00:00:00) IntroductionHost Russ Altman introduces guest Jonathan Long, a professor of pathology at Stanford University(00:02:30) Effective Weight Loss DrugsThe increase of effective weight loss drugs, and the history and development of these GLP-1 receptor agonists.(00:04:03) Understanding Metabolism and ExerciseOutline of metabolic chemicals released during physical activity and their potential to combat obesity and diabetes.(00:05:38) Animal Models in Exercise StudiesThe use of animal models in exercise studies and the discovery of Lac-Phe.(00:07:15) Psychological Preparation for ExerciseThe psychological aspects of exercise and the involvement of endocannabinoids in exercise motivation.(00:09:28) Lac-Phe's Role and MechanismThe role of Lac-Phe and its production in the gut.(00:12:21) Differences in Exercise ResponseDifferences in exercise response between trained athletes and untrained individuals.(00:13:25) Diabetes and Metabolic DiseasesThe relationship between diabetes, exercise, and metabolic diseases.(00:15:29) Lac-Phe as a Potential TherapeuticThe potential of Lac-Phe as a weight loss drug, and parallels to GLP-1 drug development.(00:16:48) Importance of How Weight is LostWhether the method of weight-loss matters, and the importance of preserving lean muscle mass.(00:19:40) Exercise as MedicineThe concept of exercise as medicine, and defining physical activity at the same resolution as modern medicines.(00:22:39) Metformin and Exercise PathwaysThe unexpected connection between metformin and the Lac-Phe pathway.(00:24:08) Prospects of an Exercise PillThe future of an exercise pill, and the scientific challenges associated with its development.(00:27:33) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads or Twitter/XConnect with School of Engineering >>> Twitter/X

An injectable antiviral "PrEP" therapy that gives 100% protection against HIV infection. Trials among young women in South Africa and Uganda proved so effective, they were wound up early to accelerate its use. Linda-Gail Bekker of the Desmond Tutu HIV Foundation shares her excitement. A new kind of gene therapy that uses the cell's own “epigenetic” mechanisms to silence troublesome portions of our DNA, tested against the prion protein responsible for some brain diseases. Jonathan Weissman led the research at the Whitehead Institute for Biomedical Research in Massachusetts. Accelerated evolution is being tested in Matthew Nitschke's labs in the Australian Institute for Marine Science to see if it can help protect natural corals against future global warming. The amazing 4.200 km transatlantic flight of some Painted Lady butterflies – and the extraordinary detective work ecologist Gerard Talavera and team needed to prove it. Presenter: Roland Pease Producer: Jonathan Blackwell Production Coordinator: Jana Bennett-Holesworth(Image: HIV Vaccine Efficacy Trial Conducted In Uganda. Credit: Luke Dray / Stringer via Getty Images.)

Happy Hour講了又講的裁員活生生的發生在若晴身上了，聽聽若晴娓娓道來在美國新創公司裁員到底是怎麼進行，到底會發生什麼事？為什麼在順利找到工作以後覺得其實是件好事？不小心聊太久只好把找工作的部分留到下一次，敬請期待！ 鼎泰豐還是台灣的好吃 夏天好熱 請期待未來GLP1藥物還有AI白話文集數 美國這兩年來裁員滾滾 募資不順、與大公司合作項目終止帶來裁員 怎麼會是我？拒絕五階段 所以到底是怎麼裁？ 眼淚狂噴的道別 跟HR簽分手協議 資遣費加失業救濟金等於加薪？！ 所以到底為什麼被裁？ 塞翁失馬焉知非福！ 下一集來聊聊connection到底是怎麼用的 有任何關於裁員或是找工作的問題歡迎提出！ -- Hosting provided by SoundOn

We're digging back into our archives with an episode with bioengineer Polly Fordyce. Polly studies the form and function of proteins. She refers to proteins as the “workhorses” that make things in the body happen, and her study of these molecules reveals a greater understanding of human life. We hope you'll tune in to this conversation again, and enjoy.Episode Reference Links:Stanford Profile: Polly FordycePolly's Lab: The Fordyce LabConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads or Twitter/XConnect with School of Engineering >>> Twitter/XChapters:(00:00:00) IntroductionHost Russ Altman introduces guest Polly Fordyce, a professor of bioengineering and genetics at Stanford University.(00:01:51) What are Proteins?The basics of proteins and their crucial roles in the body.(00:05:01) Protein Structure and FunctionThe relationship between protein structure and function.(00:07:07) Innovations in Protein ResearchThe high-throughput technologies used in the lab to study protein functions.(00:09:44) Mutant Proteins and Functional VariantsHow mutations in proteins affect their function and structure, using the example of the protein PafA.(00:14:24) The Impact of Protein Research on MedicineInsight into how protein mutations can aid in developing targeted therapies.(00:17:37) Proteins and DNA InteractionThe role of proteins in reading DNA and regulating gene expression.(00:21:41) Transcription Factors and DNA BindingThe relationship between transcription factors and specific DNA sequences.(00:25:36) Mechanisms of Transcription ActivationThe process of transcription activation and the role of co-activators and RNA polymerase.(00:28:15) Future Directions in Protein ResearchThe future of protein research, including making advanced research tools more accessible.(00:30:36) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads or Twitter/XConnect with School of Engineering >>> Twitter/X

三腳貓新手村就是玩家們交換訊息、組隊練功、甚至是一起組團打敗大魔王的地方，算算時間大家可能要準備打包來美國了，到底在登陸美國前有什麼需要注意的東西呢？ 如何找室友？如何找房子？ 浴室代表著整個房子的作工！ Whole food的存在代表著什麼呀？ 美國的距離感 Dash cam 跟保全險很重要！ 不要省小錢花大錢 但不幸花了大錢的話也就讓他過去吧～ 新手村大哉問： 有後悔帶了的東西嗎？ 有後悔沒帶的東西嗎？ 結尾：移居美國就是一個長長的旅程！ 延伸閱讀 第 005 號實驗：魔幻時刻 工作人員 內容製作：雯薇、Angel、Mike 後製：雯薇 文案：雯薇 音樂：雯薇 封面：雯薇 上架：雯薇 宣傳：Angel、雯薇 -- Hosting provided by SoundOn

AI講得震天價響這麼多年，是否真的有加速藥物開發或是提高成功率？Mike用兩篇文章當引子漫談AI在藥物開發的現況。 對AI熟悉的聽眾也可直接跳到28:00直接聽文章內容的討論。 文獻 How successful are AI-discovered drugs in clinical trials? A first analysis and emerging lessons (https://doi.org/10.1016/j.drudis.2024.104009) AI Drugs So Far (https://www.science.org/content/blog-post/ai-drugs-so-far) 節目內容 若晴工作上大變動 給新聽眾的入場須知 AI的應用講不好聽眾會放空 給很濕不乾的聽眾 AI是泛稱。你的AI不是我的AI。 AI 主導？協助？ AI的臨床研究表現真的好棒棒嗎？ 內行人的門道是？ 星際效應的書架 生成式AI下次再說… -- Hosting provided by SoundOn

We welcome back Leila Lawler to discuss false compassion and the emotional manipulation being used to sidestep the numerous moral concerns surrounding IVF. When has this strategy been used in previous cultural issues, and are Catholics on track to fall for it again?   Show Notes Like Mother, Like Daughter The aborted fetal cell research world you know nothing about The Concentration Can: When Does Human Life Begin? an Eminent Geneticist Testifies: Lejeune, Jerome Pope Paul VI Institute The Gianna Center | Catholic Health Follow Alabama's Supreme Court. IVF Is Disgusting and Evil The Effect of Conflict of Interest on Biomedical Research and Clinical Practice Guidelines: Can We Trust the Evidence in Evidence-Based Medicine? Fact and Fiction in the Alabama Frozen-Embryo Case Democrats File Bill to Make IVF a "Right," Destroying Human Beings With No Accountability - LifeNews.com Selling Embryos & Making A Killing (Dr. Tara Sander Lee) 7/10/23 Women & Children For Sale (Dr. Jennifer Roback Morse) 1/24/24 Read Fr. McTeigue's Written Works! Listen to Fr. McTeigue's Preaching! | Herald of the Gospel Sermons Podcast on Spotify Visit Fr. McTeigue's Website | Herald of the Gospel Questions? Comments? Feedback? Ask Father!

What is the underlying factor that drives humans to engage in behaviors that are damaging? Whether it's gambling, drinking, or eating to excess, it's not uncommon in our society for folks to get sucked into repetitive, detrimental habits. It turns out, there's an evolutionary foundation behind this behavior, and it's the topic of the new book, The Scarcity Brain. Today's guest, Michael Easter is a professor and the author of The Comfort Crisis and The Scarcity Brain. His work encompasses the idea of utilizing modern science and evolutionary wisdom in order to lead healthier, more fulfilled lives. He joins this episode of The Model Health Show to share the fascinating science of scarcity, moderation, fixation, and happiness. You're going to learn about the scarcity loop and how it drives us to repeat unhealthy habits. We'll talk about the psychology of gambling, overeating, excessive screen time, and so much more. If you want to break the cycle of constantly craving more, this interview will help you create meaningful change. I hope you enjoy this interview with Michael Easter! In this episode you'll discover: The interesting ways our society has removed discomfort from our daily lives. Why there's an evolutionary mismatch between our drive and our environment. What scarcity brain means. Why moderation is so difficult for most folks. What we can learn about human drive from slot machines. Three main components of a behavior loop. Examples of the scarcity loop in our modern world. The psychology of gambling. What pigeon studies on gambling can teach us about stimulation. How the theory of optimal stimulation explains addiction. Why slot machines became more popular after a few simple tweaks. How humans evolved to overeat. The fascinating history of snacking. Three v's of a popular snack. Why ultra-processed foods are easier to overeat. Three ways to fix your craving mindset. How scarcity cues can impact our behavior. The internal cues that prompt us to pick up our phones. How boredom can enhance creativity. Items mentioned in this episode include: Organifi.com/Model  -- Use the coupon code MODEL for 20% off + free shipping! Foursigmatic.com/model -- Get an exclusive discount on your daily health elixirs! Scarcity Brain by Michael Easter The Comfort Crisis by Michael Easter Connect with Michael Easter Website / Newsletter / Instagram Join TMHS Facebook community - Model Nation  Be sure you are subscribed to this podcast to automatically receive your episodes:  Apple Podcasts Stitcher Spotify Soundcloud   Thanks to our Sponsors! This episode is brought to you by Organifi. Today, more than ever, because of all the stress inputs and how our bodies are processing the data that we're being exposed to, we very often need a little bit of a support. That's where the term supplement should come in at. Supplements should not replace an already healthy diet. It should supplement, it should fill in minor gaps. It should help us to be able to go above and beyond so that we're running on all cylinders. Now, we've existed recently in recent generations in the paradigm of the "multivitamin", and the data is now pointing to the fact that there is a very big difference in synthetic versions of vitamins versus real whole food versions of those same vitamins. Just because the the chemical equation is the same does not mean that it's impacting our health the same way. Take for example, essential nutrient vitamin E. This nutrient is important for healthy function of your cardiovascular system, cognitive performance, and even the health of your skin. Well, the study published in the American Journal of Clinical Nutrition determined that natural food-based vitamin E, has nearly twice the bioavailability of synthetic vitamin E. So again, the data is now becoming more and more clear. Just because we get a "multivitamin" that has these synthetic versions of these essential nutrients, does not mean that our cells can actually utilize it. So when we're looking at fortifying our nutrition, providing ourselves with an abundance of essential nutrients, we wanna do this with number one, real whole foods. And number two, real food concentrates. Superfood concentrates. This is why I'm such a huge fan of Organifi. Organifi provides organic whole food-based superfood concentrates superfoods like chlorella, for example, which is incredibly rich in Chlorophyll, which a study published in the Journal Appetite found that chlorophyll can aid in weight loss and reduce the urge to eat hyper-palatable foods. But it also has remarkable micronutrients like Lutein and Zeaxanthin that helps with our cardiovascular system, with our vision and much more. These foods go above and beyond with their nutrient density. And on top of that, a double-blind placebo controlled study published in the journal Clinical and Experimental Hypertension found that Chlorella was able to normalize blood pressure of test subjects with hypertension. So when I'm saying these foods are superfoods, I'm not exaggerating. We're talking about science backed, we're talking about real. If we're talking about a multivitamin, this is where you need to turn, Whole Food concentrates. Organifi's Green Juice contains chlorella, spirulina, ashwagandha, coconut, and it comes together in this really refreshing beverage that's easy to make, easy to travel with as well. They have these great go packs and providing our families with real whole food-based complimentary nutrition. Go to organifi.com/model. You get 20% off their incredible Green Juice Blend. They also have a great Red Juice Formula Gold highlighting organic turmeric as the foundational ingredient in that formula. And so much more. Organifi is doing stuff the right way, organic, cold processing, organic whole food-based nutrition at organifi.com/model. That's organifi.com/model for 20% off storewide. This episode is brought to you by Four Sigmatic. The human brain is the most powerful pharmacy in the universe. And I'm saying that because every single thought that we think creates correlating chemistry in our bodies and that biochemistry is designed uniquely for you. It's beyond bio identical hormones or neurotransmitters. These are designed specifically for your own receptor site. So what you're making within your own body based on your thoughts, your perception of reality, is of the utmost importance. And obviously, thoughts of stress and anxiety, and worry and fear, these are going to create cascades that make us feel a certain way. The same with more positive and affirmative feelings and thoughts of joy, of love, of connection. But all of our emotions matter. Now, the thing is, if we're talking about health and longevity, we want to make sure that we're stacking conditions to have more positive, affirmative thoughts and buffer us from the stressful thoughts that we are inevitably going to have. Now, our sleep hygiene, our movement practices, and also our nutrition are of the utmost importance in helping to modulate these things. And when it comes to managing stress, there is one particular story, tea that has been utilized for thousands of years that stands head and shoulders above the rest. A study published in Biomedical Research found that test subjects with a variety of health complaints, including anxiety and poor sleep quality, were given lion's main medicinal mushroom or a placebo for four weeks to monitor their metabolic and psychological impact. The participants who utilize lion's mane had significantly reduced levels of anxiety and irritation than those in the placebo group. The researcher stated, quote, our results show that lion's main intake has the possibility to reduce depression and anxiety unquote. Not only that, scientists at the University of Malaya discovered that compounds in lion's mane are able to significantly improve the activity of a nerve growth factor in the brain. Nerve growth factor is essential in the regulation of growth, maintenance, proliferation and survival of various brain cells. If we want to have a healthy brain and protect our brain cells, which we don't have, the regenerative activity of brain cells like we do other cells in our bodies, we've got to take care of our brain cells. This is one of the few things ever discovered that has that protective capacity for me and my family. We want to make sure that the medicinal mushrooms that we're utilizing lions mane, chaga, rishi, and the like are all done via a dual extraction to make sure that we're getting these bio active compounds in a more full fashion. So via a hot water extract and an alcohol extract, there's one company that's doing that and infusing these incredible medicinal mushrooms into things like organic coffee, organic hot cocoa, and I'm talking about the folks at Four Sigmatic. Go to foursigmatic.com//model you get 10% off store wide of all of their incredible medicinal mushroom elixirs, cocos, and their organic coffee blends as well. Today I actually had the lions main and chaga organic coffee blend. This is one of those things, of course, it puts you on ten, but it helps you to modulate and manage your energy. It's not one of those things where you get this jolt of energy and then it leaves you lagging later on. It's very steady, mild mannered behavior and also helping to really activate the cognitive function that we're looking at when we're talking about things like lion's main, medicinal mushroom. Can get 10% off store wide plus more. They got some incredible packages that you've got to check out in specials over at foursigmatic.com//model. Go to foursigmatic.com//model for 10% off store wide and more.

Parasites are everywhere: in our bodies, in our water, even in our cats' litter boxes. Are they agents of chaos—or just misunderstood? This week, Dr. Sebastian Lourido joins Jonathan to discuss the epic world of parasites, from pinworms to toxoplasma gondii to, yes, humans. Parasites! They're everything, everywhere, all at once. Dr. Sebastian Lourido is an Associate Professor of Biology at the Massachusetts Institute of Technology and a member of the Whitehead Institute for Biomedical Research. Lourido grew up in Colombia before attending Tulane University, where he earned degrees in Art and Biology. He then worked with Arturo Zychlinsky, at the Max Planck Institute for Infection Biology, before pursuing his Ph.D. at Washington University with L. David Sibley. In 2012, in lieu of traditional postdoctoral training, Lourido started his own lab as a Whitehead Fellow studying the molecular hallmarks of apicomplexan parasitism through proteomics and functional genomics. Lourido was recruited to his present position in 2017 where he continues his research and co-teaches courses in Microbial Pathogenesis and Cell Biology. You can follow Dr. Lourido and the Lourido Lab on Twitter @LouridoLab, @WhiteheadInst and @MITBiology. For more information, check out the websites for the Lourido Lab and Whitehead Institute. Curious for more? Check out these episodes from the archive: Are Mushrooms Truly Magic? How Does Dust Impact Earth's Climate? When Viruses Spread, Who's Most Vulnerable? Can You Say Cheese? Follow us on Instagram @CuriousWithJVN to join the conversation. Jonathan is on Instagram @JVN. Transcripts for each episode are available at JonathanVanNess.com. Find books from Getting Curious guests at bookshop.org/shop/curiouswithjvn. Our executive producer is Erica Getto. Our producer is Chris McClure. Our associate producer is Allison Weiss. Our engineer is Nathanael McClure. Production support from Julie Carrillo. Our theme music is “Freak” by QUIÑ; for more, head to TheQuinCat.com. Curious about bringing your brand to life on the show? Email podcastadsales@sonymusic.com. Learn more about your ad choices. Visit podcastchoices.com/adchoices