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Fluoroquinolones (FQs) are valuable given their broad-spectrum activity against Gram-positive and Gram-negative bacteria and their high penetration into various tissues. Yet FQs have also caused concern, with some market withdrawals, important and sometimes long-lasting adverse drug events, and substantial collateral effects on the microbiota. In this episode of Communicable, hosts Emily McDonald and Thomas Tängdén invite Staffan Tevell (Karlstad, Sweden) and Bernadette Young (Oxford, UK) to weigh in on the pro-con debate of FQ use, especially for periprosthetic joint infections (PJIs), which can entail longer treatment durations. They review the standard of care for PJIs, including FQs in combination with rifampicin vs other antibiotic combinations, the impact of the OVIVA trial advocating for early oral switch strategies, the long list of rare but important side effects, and how best to preserve FQs for clinical indications that most need them. This episode is a follow-up from Tevell and Young's recently published systematic review of the role of FQs in PJIs [1]. It was edited by Kathryn Hostettler and peer reviewed by Ljiljana Lukić of University Hospital for Infectious Diseases in Zagreb, Croatia. The executive producer of Communicable is Angela Huttner. ReferencesTevell S, et al. To heal or harm: A systematic review of the role of fluoroquinolones in periprosthetic joint infections. CMI Communications 2025. DOI: 10.1016/j.cmicom.2025.105103Further readingMandell LA, et al. Antimicrobial Safety and Tolerability: Differences and Dilemmas. Clin Infect Dis 2001. JSTOR http://www.jstor.org/stable/4461522.Pham TDM, et al. Quinolone antibiotics. Medchemcomm 2019. DOI: 10.1039/c9md00120d. Rodrigues CF and Silva F. The Rise, Fall, and Rethink of (Fluoro)quinolones: A Quick Rundown. Pathogens 2025. DOI: 10.3390/pathogens14060525Slimings C and Riley TV. Antibiotics and hospital-acquired Clostridium difficile infection: update of systematic review and meta-analysis. J Antimicrob Chemother 2014. DOI: 10.1093/jac/dkt477Davis JS, et al. Predictors of treatment success after periprosthetic joint infection: 24-month follow up from a multicenter prospective observational cohort study of 653 patients. Open Forum Infect Dis 2022. DOI: 10.1093/ofid/ofac048.Grossi O, et al. Gram- negative prosthetic joint infections managed according to a multidisciplinary standardized approach: risk factors for failure and outcome with and without fluoroquinolones. J Antimicrob Chemother 2016. DOI: 10.1093/jac/dkw202 Cortes-Penfield NW, et al. Adjunctive rifampin following debridement and implant retention for staphylococcal prosthetic joint infection: is it effective if not combined with a fluoroquinolone? Open Forum Infect Dis 2022. DOI: 10.1093/ofid/ofac582Pushkin R, et al. A Randomized Study Evaluating Oral Fusidic Acid (CEM-102) in Combination With Oral Rifampin Compared With Standard-of-Care Antibiotics for Treatment of Prosthetic Joint Infections: A Newly Identified Drug-Drug Interaction. Clin Infect Dis 2016. DOI: 10.1093/cid/ciw665Bock M, et al. Rifampicin reduces plasma concentration of linezolid in patients with infective endocarditis. J Antimicrob Chemother 2023. DOI: 10.1093/jac/dkad316 Zeller V, et al. Influence of the clindamycin administration route on the magnitude of clindamycin-rifampicin interaction: a prospective pharmacokinetic study. Clin Microbiol Infect. 2021. DOI: https://doi.org/10.1016/j.cmi.2021.04.017 Bernard L, et al. Antibiotic Therapy for 6 or 12 Weeks for Prosthetic Joint Infection. N Engl J Med 2021. DOI: 10.1056/NEJMoa2020198Vollmer NJ, et al. Safety and Tolerability of Fluoroquinolones in Patients with Staphylococcal Periprosthetic Joint Infections, Clin Infect Dis 2021. DOI 10.1093/cid/ciab145Gopalakrishnan C, et al. Association of fluoroquinolones with the risk of aortic aneurysm or aortic dissection. JAMA Intern Med 2020. DOI 10.1001/jamainternmed.2020.4199Li HK, et al. Oral versus Intravenous Antibiotics for Bone and Joint Infection (OVIVA). N Engl J Med. 2019. DOI: 10.1056/NEJMoa1710926
Have the Bulldogs made a statement? Does Jahrome Hughes' injury put a dint in Melbourne's premiership push? Have Wests Tigers got the most out of Jarome Luai? How do the massive upsets impact the seemingly settled top four? All that and more in the ABC NRL Daily wrap up of NRL Round 21 and NRLW Round 4 with Brett Sprigg and Andrew Moore.
In this episode of Quah (Q & A), Sal, Adam & Justin answer four Pump Head questions drawn from last Sunday's Quah post on the @mindpumpmedia Instagram page. Mind Pump Fit Tip: 9 Reasons Getting Stronger is the Best Physical Pursuit. (1:58) The different stages of raising a child. (24:07) The ultimate nootropic, methylene blue. (42:27) Peeing outside. (48:16) Sauna/hot tub and sodium. (50:01) When your hormones are feeling REALLY good. (52:06) Kids say the darndest things. (56:00) #Quah question #1 – What are your thoughts on day-long workouts? I work from home most days, and I like to spread my workout throughout the day. (57:45) #Quah question #2 – How to break through plateaus? I've been stuck on preacher curls, among other exercises, for two months. (1:02:39) #Quah question #3 – I'm about as beginner as a beginner can get when it comes to lifting, to the point that I don't know how to get started, and I have no clue what my baseline is. Do I just go to the weight bench and throw on some plates? What is the very first step for someone who has never lifted? (1:04:40) #Quah question #4 – You always mention going for a walk after a meal. Does going before eating have the same benefits or not? (1:09:09) Related Links/Products Mentioned Visit Troscriptions for the exclusive offer for Mind Pump listeners! **Promo code MINDPUMP for 10% off your first order. ** Get your free Sample Pack with any “drink mix” purchase! Find your favorite LMNT flavor, or share it with a friend. Try LMNT risk-free. If you don't like it, give it away to a salty friend and we'll give you your money back, no questions asked! Visit DrinkLMNT.com/MindPump July Special: MAPS Split or Anabolic Metabolism Bundle 50% off! ** Code JULY50 at checkout ** Association of Grip Strength With Risk of All-Cause Mortality, Cardiovascular Diseases, and Cancer in Community-Dwelling Populations: A Meta-analysis of Prospective Cohort Studies Muscular Strength as a Predictor of All-Cause Mortality in an Apparently Healthy Population: A Systematic Review and Meta-Analysis of Data From Approximately 2 Million Men and Women Exercise interventions for older adults: A systematic review of meta-analyses Association of Efficacy of Resistance Exercise Training With Depressive Symptoms: Meta-analysis and Meta-regression Analysis of Randomized Clinical Trials Adherence to Strength Training and Lower Rates of Sports Injury in Contact Sports: A Systematic Review and Meta-analysis Parenting: Getting It Right Visit Paleovalley for an exclusive offer for Mind Pump listeners! ** Discount is now automatically applied at checkout: 15% off your first order! ** Mind Pump # 2552: From Plateau to PR… How to Break Through Strength Barriers Mind Pump # 2385: Five Reasons Why You Should Hire a Trainer Mind Pump Podcast – YouTube Mind Pump Free Resources People Mentioned LAUREN FITZ, M.D. (@drlaurenfitz) Instagram
Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Baseline Cardiac Biomarker Levels as Predictors of Cancer Risk in the MESA Cohort.
In this new episode of Speaking of SurgOnc, Dr. Rick Greene discusses with Dr. Eduardo Vega the identification of risk factors for futile surgery in gallbladder cancer and the development of a predictive model to guide clinicians in selecting patients most likely to benefit from surgery, as reported in the article, "Optimizing Outcomes in Gallbladder Cancer: Identifying Predictors of Futile Up-Front Surgery in a Global Multi-center Study.”
Fitness mit M.A.R.K. — Dein Nackt Gut Aussehen Podcast übers Abnehmen, Muskelaufbau und Motivation
Stell Dir vor, Dein Körper ist ein Sportwagen. Kraftvoll, elegant – aber Du fährst ihn im ersten Gang durchs Leben. Warum? Weil Du den eigentlichen Motor nie wirklich nutzt: Deine Wirbelsäule.Klingt sonderbar? Dachte ich zunächst auch.In diesem Artikel lernst Du ein Konzept kennen, das Deine Sicht auf Bewegung auf den Kopf stellt – wortwörtlich. Du lernst das Geheimnis der „Spinal Engine“ kennen, ein wenig bekanntes und dennoch mächtiges biomechanisches Modell. Es erklärt, warum Deine Wirbelsäule vielleicht der eigentliche Antrieb jeder Deiner Bewegungen ist – und nicht, wie viele denken, nur Deine Beine oder Dein Core.____________*WERBUNG: Infos zum Werbepartner dieser Folge und allen weiteren Werbepartnern findest Du hier.____________
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In "What's the No. 1 Predictor of Personal Growth? (Part 1)," we explored whether shame, if it inspires growth and motivates change, has a place in our lives. In this follow-up episode, Kelsea and Rachael delve into various types of shame and how pride influences its effectiveness. Even if you missed the first part, you'll gain five valuable tips on harnessing shame for your benefit rather than letting it control you. Don't feed the beast! Discover evidence-based strategies to make lasting changes in your life that have previously been a struggle!NIH Study Link: Shame and the motivation to change the self(00:01:13) Welcome to the Podcast and a look back at part 1.(00:07:14) What will make lasting changes in our lives?(00:12:03) Where the problem comes in: the “not ok” shame.(00:19:55) Baseline values and shame around food. (00:31:06) Setting fitness goals. (00:33:30) Tip #1: Name the emotion.(00:40:00) Tip #2: Don't hold it in.(00:44:30) Tip #3: Practice empathy for yourself.(00:47:59) Tip #4: Identify your triggers.(00:52:51) Tip #5: Set some boundaries.(00:57:45) Cutting corners and your ideal.Want to leave the TTSL Podcast a voicemail? We love your questions and adore hearing from you. https://www.speakpipe.com/TheThickThighsSaveLivesPodcastThe CVG Nation app, for iPhoneThe CVG Nation app, for AndroidOur Fitness FB Group.Thick Thighs Save Lives Workout ProgramsConstantly Varied Gear's Workout Leggings
In this conversation, Joel Evan and Blair LaCorte explore the multifaceted aspects of longevity and anti-aging. They discuss how aging can be viewed as an outdated operating system that can be upgraded through lifestyle changes, particularly focusing on the role of chronic inflammation, genetics, and community. Blair emphasizes the importance of balancing the nervous system, the lessons learned from Blue Zones, and the need for personalized health strategies. The discussion also touches on the significance of daily movement, nutrition, and mindset in achieving a fulfilling and longer life.Chapters00:00 Introduction to Longevity and Anti-Aging06:10 The Importance of Health Span vs. Longevity14:00 The Power of Connection and Community19:55 Debating the Blue Zones and Longevity Practices28:23 Balancing High and Low Intensity Training34:08 Navigating Genetic Testing and Health Insights39:35 Evaluating Supplements and Their Efficacy45:01 Changing Habits for a Healthier Future
Gary, Gavin and Graham try not to take too much notice of our opening pre-season games before we show just how little we know about the game with our 2025-26 Season Predictor. Become a paid subscriber over at abzfootballpodcast.com Follow us on our social media channels:- Twitter - @AbzPodcast Facebook - @ABZFootballPodcast Instagram - @abzfootballpodcast
On this episode of Translating Proteomics, Parag, Andreas, and special guest Don Kirkpatrick answer questions submitted by the Translating Proteomics community. They cover:Needs in plasma proteomicsHow proteomics impacts drug development – with special guest Don Kirkpatrick Ph.D.!How lifestyle impacts the proteomeHow the Nautilus Proteome Analysis Platform is impacting tau and Alzheimer's disease researchReferencesShome et al., 2022 - Serum autoantibodyome reveals that healthy individuals share common autoantibodieshttps://www.sciencedirect.com/science/article/pii/S2211124722006489LaBaer Lab paper investigating autoantibody levels in plasma and their relationship to health.Sylman et al., 2018 - A Temporal Examination of Platelet Counts as a Predictor of Prognosis in Lung, Prostate, and Colon Cancer Patientshttps://www.nature.com/articles/s41598-018-25019-1Mallick lab paper investigating temporal changes in platelets and their associations with cancer biology.Krönke et al., 2014 - Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cellshttps://www.science.org/doi/10.1126/science.1244851Seminal paper describing selective protein degradation caused by lenalidomide.Fink and Ebert 2015 - The novel mechanism of lenalidomide activityhttps://ashpublications.org/blood/article/126/21/2366/34644/The-novel-mechanism-of-lenalidomide-activityReview of research elucidating the mechanisms of lenalidomide activityNdoja et al., 2025 - COP1 Deficiency in BRAFV600E Melanomas Confers Resistance to Inhibitors of the MAPK Pathwayhttps://www.mdpi.com/2073-4409/14/13/975Describe links between kinase inhibitor vemurafenib and changes in ETV transcription factor degradationSong et al., 2022 - RTK-Dependent Inducible Degradation of Mutant PI3Kα Drives GDC-0077 (Inavolisib) Efficacyhttps://aacrjournals.org/cancerdiscovery/article/12/1/204/675622/RTK-Dependent-Inducible-Degradation-of-Mutant-PI3KUse proteomics to discover that inavolisib acts through selective degradation of mutant PI3KαCanon et al., 2019 - The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunityhttps://www.nature.com/articles/s41586-019-1694-1Covers the development of an inhibitor of KRAS mutant KRAS (G12C).Schneider et al., 2024 - Feeding gut microbes to nourish the brain: unravelling the diet-microbiota-gut-brain axishttps://www.nature.com/articles/s42255-024-01108-6Review on the gut-brain axisWebpage for Johanna Lampe's Lab at Fred Hutch Cancer Center
New Patient Group™ (Formally known as the Doctor Diamond Club Podcast)
Send us a textClick here to subscribe to The Brian Wright Show Podcast Click here to subscribe The Brian Wright Show YouTube Station Click here to subscribe to the New Patient Group YouTube Station.Click here to register you and your team for NPG Iconic. Click here to schedule free consultation with New Patient Group and/or WrightChat The gap between knowing and doing might be the single greatest predictor of success in business and life. In this thought-provoking episode, Brian Wright tackles the dangerous misconception that gathering information alone leads to progress.Have you ever found yourself researching, planning, and preparing for so long that you never actually take the first step? You're experiencing what psychologists call the "Deep Dive Effect" – the tendency to seek excessive information before taking action, often resulting in decision paralysis or missed opportunities. Brian shares the eye-opening story of meeting a young man who had spent two years preparing to launch a podcast without recording a single episode, perfectly illustrating how knowledge without implementation becomes wasted potential.The most successful business leaders don't wait for perfect information. They adopt a "ready, shoot, aim" approach – launching initiatives quickly, learning from real feedback, and refining as they go. Meanwhile, their competition remains stuck in research mode, paralyzed by contradicting advice and information overload. This pattern proves especially challenging for professionals with analytical minds, like clinicians or engineers, whose training emphasizes precision over action.What truly sets top-performing businesses apart isn't superior knowledge but superior implementation. While the masses flock to marketing seminars, the elite few obsess over creating remarkable customer experiences that turn clients into advocates. They build systems that differentiate their business at every touchpoint, recognizing that external competition isn't their real challenge – their ability to implement knowledge effectively is.Remember: your greatest competitor isn't the new business opening down the street. It's your willingness to act on what you know, even imperfectly. Start with small steps, learn through implementation, and understand that knowledge without action is just expensive education. Your success depends not on what you know, but on what you do with what you know.New Patient Group - The Employee & Patient Experience Co.A company designed to help orthodontists, dentists and other types of Doctors create a practice that dominates the new economy. Learn Advanced and Cutting Edge Skill Sets Used by the Finest People Businesses in the World, such as the Ritz Carlton and other famous Companies: - Leadership- Sales Fundamentals- Hospitality- Consumer Psychology- Verbiage- Presentation- Many More Learn How to Apply the Skill Sets Above to each of the following:- Existing Patient Experience- New Patient Experience- New Patient Phone Call- Existing Patient Phone Call- Digital Workflow- Treatment Coordinator Exam- Doctor Exam- Financial Presentation- Pending Treatment FollowUp- Handling and Overcoming Objections - Trust & Communication Transfers - Digital Marketing- Patient Compliance- Clinical Assistant Chair Side Conversations- Clinical Assistant Conversation with Parents - Re
Lung cancer has a high chance of relapse, so how do we get out of ahead of it? Nancy Guo, SUNY Empire Innovation Professor in the school of computing at Binghamton University, discusses technology that helps us do so. Nancy Guo is one of the newest additions to the Binghamton University School of Computing as […]
Remember that gut-clenching fear of speaking up in class? Organizational psychologist Rafael Chiuzi reveals how that same feeling shows up in the workplace, limiting productivity and the free exchange of ideas. Backed by decades of research and hands-on consulting, he unpacks the science of psychological safety — and shares three actionable steps to build teams where curiosity thrives and courage replaces fear.Want to help shape TED's shows going forward? Fill out our survey!For a chance to give your own TED Talk, fill out the Idea Search Application: ted.com/ideasearch.Interested in learning more about upcoming TED events? Follow these links:TEDNext: ted.com/futureyou Hosted on Acast. See acast.com/privacy for more information.
For years, disease diagnosis and treatment have focused on a few biomarkers, overlooking thousands of vital biological signals. Despite biotech advances, most therapies are still based on limited data, missing countless breakthroughs.Multiomics changes that. By analyzing tens of thousands of proteins, metabolites, and lipids, it reveals hidden insights, paving the way for smarter, faster, and more effective medical discoveries.In this must-listen episode, David Brühlmann welcomes Mo Jain, founder and CSO of Sapient, a pioneering force in bringing multiomic platforms out of academia and into the heart of drug development. A physician-scientist by training and a visionary entrepreneur by choice, Mo's journey spans decades at the cutting edge of analytical technologies, culminating in the creation of ultra-high-throughput systems that analyze up to 20,000 biomarkers in a single run for real-world impact.Here are three reasons why this episode needs to be on your playlist:Multiomics at Scale: Mo shares how his team at Sapient turbocharged mass spectrometry, enabling simultaneous measurement of thousands of molecules, transforming routine diagnostics and making previously unimaginable insights accessible to scientists everywhere.Turning Data into Action: Generating vast data is only half the battle. Mo explains how Sapient developed advanced biocomputational teams and frameworks to extract actionable answers, guiding drug developers to faster, smarter decisions and helping avoid the pitfalls that cripple so many omics projects.The Future Is Personalized and Sooner Than You Think: From dramatically earlier disease detection to truly personalized therapies, Mo paints an optimistic picture of a coming era where AI, multiomics, and new therapeutic modalities rapidly accelerate both discovery and delivery, reshaping how biotech companies tackle even the toughest diseases.Ready to break out of the 20-biomarker rut and see what 20,000 data points can reveal? Tune in to discover how you can harness multiomics in your own research and hear Mo's advice for scientists and entrepreneurs venturing beyond the bench.Connect with Mo Jain:LinkedIn: www.linkedin.com/in/mo-jain-md-phd-373895baWebsite: www.sapient.bioCompany LinkedIn Page: https://www.linkedin.com/company/sapientbioNext step:Book a free consultation to help you get started on any questions you may have about bioprocessing analytics: https://bruehlmann-consulting.com/callDevelop bioprocessing technologies better, faster, at a fraction of the cost with our 1:1 Strategy Call: The quickest and easiest way to excel biotech technology development. Book your call at https://stan.store/SmartBiotechSupport the show
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What if the secret to truly personalized precision medicine lies not in your genetic code, but in your zip code?For years, biotech has focused on genomics to explain disease and drug response, but DNA only accounts for a fraction of the story. The real breakthrough? Multi-omics: the large-scale analysis of proteins, metabolites, and lipids, powered by advanced mass spectrometry and AI, offering a fuller picture of human health.In this episode, David Brühlmann meets Mo Jain, founder and CSO of Sapient, a leader in multi-omics analytics. With over two decades of experience across physiology, biomedicine, and computational biology, Mo has been at the forefront of developing scalable multi-omics technologies that are changing the way we predict, diagnose, and treat disease. From leading an academic lab to building a pioneering biotech company, Mo's journey reflects a passion for uncovering the hidden 80–90% of disease risk that lies beyond our genes.Here are three reasons you'll want to listen to this episode:Your Environment Matters More Than Your Genes: Mo explains why your zip code is a stronger predictor of your health than your genetic code, challenging the industry's long-held beliefs and opening new avenues for disease prevention and risk assessment.Multi-omics Disrupts Drug Development: Discover how integrating thousands of biological data points can revolutionize drug discovery by identifying novel targets, better predicting drug response, and accelerating therapeutic breakthroughs that were previously out of reach.Big Data Finally Becomes Actionable: Thanks to rapid advances in mass spectrometry and computational power, scientists can now make sense of overwhelming volumes of multi-omic data, turning what was once information overload into actionable insights for diagnostics and drug development.Ready to think beyond your genes? The biotech revolution is here, and it starts in your neighborhood.Connect with Mo Jain:LinkedIn: www.linkedin.com/in/mo-jain-md-phd-373895baWebsite: www.sapient.bioCompany LinkedIn Page: https://www.linkedin.com/company/sapientbioNext step:Book a free consultation to help you get started on any questions you may have about bioprocessing analytics: https://bruehlmann-consulting.com/callDevelop bioprocessing technologies better, faster, at a fraction of the cost with our 1:1 Strategy Call: The quickest and easiest way to excel biotech technology development. Book your call at https://stan.store/SmartBiotechSupport the show
In today's episode, I'm joined by the brilliant Logan Ury—behavioral scientist, dating coach, and author of How to Not Die Alone. We dive deep into the messy and sometimes painfully confusing world of modern dating. From the myths that keep us single to the science-backed truths about real lasting connection, Logan shares tons of actionable advice. We chat about how vulnerability and timing play crucial roles in finding a great match, why dating apps feel so overwhelming, what people think they want versus what actually leads to a long-term partnership, her “Three Dating Tendencies” framework, and how to stop self-sabotaging when it comes to finding your forever person. Whether you're single and swiping, newly partnered, or just relationship-curious, this conversation is packed with insights that will totally reframe how you approach dating, relationships, and yourself. We will also be discussing the romantic comedy movie that just came out: The Materialist. If you don't want to hear spoilers about the movie's ending, stop listening when Liz gives a heads-up—around 44:40 on Spotify video or after the second ad break on Apple audio—and come back after you've seen it to hear Liz's and Logan's different hot takes! In this episode, we get into: How to date like a scientist Finding your true deal-breakers Emotional intelligence & dating Money & dating Predictors of long-term success The stress test Physical expectations & dating If love is enough Modern masculinity & modern femininity Relation shopping vs. relation shipping Hot takes on the materialist movie For more from Logan Ury, find her on Instagram @loganury or online at www.loganury.com to check out her newsletter and matchmaking services. Read her book, How To Not Die Alone. Ready to uplevel every part of your life? Order Liz's book 100 Ways to Change Your Life: The Science of Leveling Up Health, Happiness, Relationships & Success now! Connect with Liz on Instagram @lizmoody or online at www.lizmoody.com. Subscribe to the substack by visiting https://lizmoody.substack.com/welcome. To join The Liz Moody Podcast Club Facebook group, go to www.facebook.com/groups/thelizmoodypodcast. This episode is brought to you completely free thanks to the following podcast sponsors: Shopify: Sign up for a one-dollar-per-month trial period at shopify.com/lizm. Maui Nui: Head to mauinuivenison.com/LIZ to secure your access to a limited collection of Liz's favorite nutrient-dense wildly delicious meat cuts and products. LMNT: Go to DrinkLMNT.com/LizMoody to get a free LMNT sample pack with any order. Evlo: Head to EvloFitness.com and use code LIZMOODY to get 6 full weeks completely FREE. The Liz Moody Podcast cover art by Zack. The Liz Moody Podcast music by Alex Ruimy. Formerly the Healthier Together Podcast. This podcast and website represents the opinions of Liz Moody and her guests to the show. The content here should not be taken as medical advice. The content here is for information purposes only, and because each person is so unique, please consult your healthcare professional for any medical questions. The Liz Moody Podcast Episode 343. Learn more about your ad choices. Visit megaphone.fm/adchoices
The Real Truth About Health Free 17 Day Live Online Conference Podcast
This conversation explores the complexities of addiction treatment through the perspectives of two professionals, Heather and Josh, who share their personal journeys and insights into the stigma, politics, and treatment approaches surrounding addiction. They discuss the importance of understanding the underlying causes of addiction, the role of choice, and the need for comprehensive education and support systems to effectively address addiction in society. Know more about Josh & Heather's work: Addiction2recovery Podcast Book "Trauma's Worth" by Heather Bell Know more about Sathiya's work: JOIN DEEP CLEAN INNER CIRCLE Got a Question? Submit It Anonymously Through This Form Get A Free Copy of The Last Relapse, A Blueprint For Recovery Watch Sathiya on Youtube For More Content Like This Chapters: (00:00) Introduction to Addiction Medicine (01:53) The Journey into Addiction Treatment (10:11) Personal Stories of Addiction and Recovery (14:00) The Stigma Surrounding Addiction (23:05) Is Addiction a Choice? (29:46) Predictors of Addiction (37:15) The Role of Support Systems (46:29) Addressing Co-occurring Disorders (54:44) The Future of Addiction Treatment (1:00:50) Conclusion and Resources
Pan Am Airlines is back after 34 years, but with a hotel, theater, & cafe… Because Brands > Logos.Apple's Formula1 movie premiers today… Brad Pitt proves how Hollywood powers Wall Street.The newest industry to know is PeaceTech… because AI can predict (and prevent) war.Plus, the hottest industry in this economy?... Matchmaking coaches.$DAL $AAPL $PLTRWant more business storytelling from us? Check out the latest episode of our new weekly deepdive show: The untold origin story of… Subscribe to The Best Idea Yet: Wondery.fm/TheBestIdeaYetLinks to listen.TBOY Live Show Tickets to Chicago on sale NOW: https://www.axs.com/events/949346/the-best-one-yet-podcast-ticketsAbout Us: The daily pop-biz news show making today's top stories your business. Formerly known as Robinhood Snacks, TBOY Lite is hosted by Jack Crivici-Kramer & Nick Martell.GET ON THE POD: Submit a shoutout or fact: https://tboypod.com/shoutouts NEWSLETTER:https://tboypod.com/newsletter SOCIALS:Instagram: https://www.instagram.com/tboypod TikTok: https://www.tiktok.com/@tboypodYouTube: https://www.youtube.com/@tboypod Anything else: https://tboypod.com/ Our 2nd show… The Best Idea Yet: Wondery.fm/TheBestIdeaYetLinksEpisodes drop weekly.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
This week on The Beat, CTSNet Editor-in-Chief Joel Dunning speaks with Dr. David Kalfa, the incoming Chief of Pediatric Cardiac Surgery and Co-Director of the Heart Institute at Nicklaus Children's Hospital in Miami, about allogeneic mitral valve transplants. Chapters 00:00 Intro 01:46 Interview Preview 02:54 MV Surgery After Failed Intervention 07:46 Tears Predict Outcomes After Hemi-Arch 10:32 Pain Catastrophizing Scale 14:27 ARR w Stentless Biopros, Sex Difference 16:38 Open Implant TAV via Redo Sternotomy 19:05 Repeat Sternotomy w Completion Unifocaliz 21:07 Direct Aortic Impella 5.5 in PC Shock 25:16 Dr. Kalfa Interview, AMV Transplant 39:58 Upcoming Events 41:26 Closing They discuss methods for obtaining a mitral valve for transplantation, and topics such as immunosuppression, aortic coagulation, and the progress that has been made in this field. They also explore how to perform a living allogeneic heart valve transplant and the future of this technique. Joel also highlights recent JANS articles on mitral valve surgery after failed transcatheter intervention for mitral regurgitation, whether distal anastomotic new entry tears predict long-term outcomes after hemiarch repair for DeBakey I aortic dissection, using a pain catastrophizing scale as a predictor for acute postoperative pain following video-assisted thoracoscopic surgery lobectomy, and sex difference in aortic root replacement with a stentless bioprosthesis. In addition, Joel explores an open implantation of a transcatheter aortic valve via redo sternotomy, mitral valve replacement, and tricuspid valve repair in a high-risk patient, repeat sternotomy with completion unifocalization and extensive pulmonary arterial reconstruction in ToF/PA/MAPCAs, and direct aortic Impella 5.5 in post-cardiotomy shock. Before closing, Joel highlights upcoming events in CT surgery. JANS Items Mentioned 1.) Mitral Valve Surgery After Failed Transcatheter Intervention for Mitral Regurgitation: Techniques, Challenges, and Outcomes 2.) Distal Anastomotic New Entry Tears Predict Long-Term Outcomes After Hemi-Arch Repair for DeBakey I Aortic Dissection 3.) Pain Catastrophizing Scale as a Predictor for Acute Postoperative Pain Following Video-Assisted Thoracoscopic Surgery Lobectomy 4.) Sex Difference in Aortic Root Replacement With a Stentless Bioprosthesis CTSNET Content Mentioned 1.) Open Implantation of a Transcatheter Aortic Valve via Redo Sternotomy, Mitral Valve Replacement, and Tricuspid Valve Repair in a High-Risk-Patient 2.) Challenging Pulmonary Arterial Reconstruction: Repeat Sternotomy With Completion Unifocalization and Extensive Pulmonary Arterial Reconstruction in ToF/PA/MAPCAs 3.) Direct Aortic Impella 5.5 in Post-Cardiotomy Shock Other Items Mentioned 1.) Allogeneic Mitral Valve Transplant: Historical Precedent, Current Considerations, and Future Implementation 2.) Cardiac Surgical Arrest—An International Conversation, Part 1 3.) Winners of the 2025 CTSNet Instructional Video Competition 4.) Career Center 5.) CTSNet Events Calendar Disclaimer The information and views presented on CTSNet.org represent the views of the authors and contributors of the material and not of CTSNet. Please review our full disclaimer page here.
Which property markets are heating up—and which are cooling down? In this episode of The Property Playbook, Tim Graham sits down with Australia's leading independent property analyst, Terry Ryder of Hotspotting, to unpack the insights from the Winter 2025 edition of the Price Predictor Index. Discover which capital cities and regional areas are showing the strongest buyer demand right now, which markets are entering a second growth wave, and why Sydney has fallen to last place.
Today we are talking about an uncomfortable word in a new light: shame. We are taking another look at a concept reserved for negativity and therapist couches and asking ourselves if there's actually room for shame in our lives if it inspires personal growth and motivates change. In other words, is there a time and place for shame? Today Rachael and Kelsea find themselves on opposite sides of the discussion even though they are sisters brought up in the same household with the same dose of shame going around. Tune in to hear both sides in part 1 of this thoughtful examination of something that lives deep inside all of us, like it or not. (00:03:30) Rachael and Kelsea laugh about differences between MA and FL (00:12:11) Life update, Kelsea's hair is growing back. (00:17:11) Why Kelsea and Rachael feel differently about today's topic: shame (00:22:10) How Rachael's mom inspired this conversation(00:26:14) Kelsea thinks of shame as something that has held her back but has also led her to accountability. (00:30:40) Rachael points out a study that finds shame is the #1 predictor of personal growth.(00:34:00) Kelsea thinks. shame can make people draw away from accountability and can disconnect people(00:36:00) Rachael focuses on the distinction between personal shame and someone else's.(00:42:00) Part 2 will focus on negative behaviors around eating, motivation to workout and shame-resilience strategies.Want to leave the TTSL Podcast a voicemail? We love your questions and adore hearing from you. https://www.speakpipe.com/TheThickThighsSaveLivesPodcastThe CVG Nation app, for iPhoneThe CVG Nation app, for AndroidOur Fitness FB Group.Thick Thighs Save Lives Workout ProgramsConstantly Varied Gear's Workout Leggings
Description: Co-hosts Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist living with EoE who serves on APFED's Health Sciences Advisory Council, interview Anna Henderson, MD, a pediatric gastroenterologist at Northern Light Health in Maine, about bone mineral density in EoE patients. They discuss a paper she co-authored on the subject. Disclaimer: The information provided in this podcast is designed to support, not replace, the relationship that exists between listeners and their healthcare providers. Opinions, information, and recommendations shared in this podcast are not a substitute for medical advice. Decisions related to medical care should be made with your healthcare provider. Opinions and views of guests and co-hosts are their own. Key Takeaways: [:50] Co-host Ryan Piansky introduces the episode, brought to you thanks to the support of Education Partners Bristol Myers Squibb, Sanofi, Regeneron, and Takeda. Ryan introduces co-host Holly Knotowicz. [1:17] Holly introduces today's topic, eosinophilic esophagitis (EoE), and bone density. [1:22] Holly introduces today's guest, Dr. Anna Henderson, a pediatric gastroenterologist at Northern Light Health in Maine. [1:29] During her pediatric and pediatric gastroenterology training at Cincinnati Children's Hospital, she took a special interest in eosinophilic esophagitis. In 2019, Dr. Henderson received APFED's NASPGHAN Outstanding EGID Abstract Award. [1:45] Holly, a feeding therapist in Maine, has referred many patients to Dr. Henderson and is excited to have her on the show. [2:29] Dr. Henderson is a wife and mother. She loves to swim and loves the outdoors. She practices general pediatric GI in Bangor, Maine, at a community-based academic center. [2:52] Her patient population is the northern two-thirds of Maine. Dr. Henderson feels it is rewarding to bring her expertise from Cincinnati to a community that may not otherwise have access to specialized care. [3:13] Dr. Henderson's interest in EoE grew as a GI fellow at Cincinnati Children's. Her research focused on biomarkers for disease response to dietary therapies and EoE's relationship to bone health. [3:36] As a fellow, Dr. Henderson rotated through different specialized clinics. She saw there were many unanswered questions about the disease process, areas to improve treatment options, and quality of life for the patients suffering from these diseases. [4:00] Dr. Henderson saw many patients going through endoscopies. She saw the social barriers for patients following strict diets. She saw a huge need in EoE and jumped on it. [4:20] Ryan grew up with EoE. He remembers the struggles of constant scopes, different treatment options, and dietary therapy. Many people struggled to find what was best for them before there was a good approved treatment. [4:38] As part of Ryan's journey, he learned he has osteoporosis. He was diagnosed at age 18 or 19. His DEXA scan had such a low Z-score that they thought the machine was broken. He was retested. [5:12] Dr. Henderson explains that bone mineral density is a key measure of bone health and strength. Denser bones contain more minerals and are stronger. A low bone mineral density means weaker bones. Weaker bones increase the risk of fracture. [5:36] DEXA scan stands for Dual Energy X-ray Absorptiometry scan. It's a type of X-ray that takes 10 to 30 minutes. A machine scans over their bones. Typically, we're most interested in the lumbar spine and hip bones. [5:56] The results are standardized to the patient's height and weight, with 0 being the average. A negative number means weaker bones than average for that patient's height and weight. Anything positive means stronger bones for that patient's height and weight. [6:34] A lot of things can affect a patient's bone mineral density: genetics, dietary history, calcium and Vitamin D intake, and medications, including steroid use. Prednisone is a big risk factor for bone disease. [7:07] Other risk factors are medical and auto-immune conditions, like celiac disease, and age. Any patient will have their highest bone density in their 20s to 30s. Females typically have lower bone mineral density than males. [7:26] The last factor is lifestyle. Patients who are more active and do weight-bearing exercises will have higher bone mineral density than patients who have more of a sedentary lifestyle. [7:56] Ryan was told his bone mineral density issues were probably a side-effect of the long-term steroids he was on for his EoE. Ryan is now on benralizumab for eosinophilic asthma. He is off steroids. [8:36] Dr. Henderson says the research is needed to find causes of bone mineral density loss besides glucocorticoids. [8:45] EoE patients are on swallowed steroids, fluticasone, budesonide, etc. Other patients are on steroids for asthma, eczema, and allergic rhinitis. These may be intranasal steroids or topical steroids. [9:01] Dr. Henderson says we wondered whether or not all of those steroids and those combined risks put the EoE population at risk for low bone mineral density. There's not a lot published in that area. [9:14] We know that proton pump inhibitors can increase the risk of low bone mineral density. A lot of EoE patients are on proton pump inhibitors. [9:23] That was where Dr. Henderson's interest started. She didn't have a great way to screen for bone mineral density issues or even know if it was a problem in her patients more than was expected in a typical patient population. [9:57] Holly wasn't diagnosed with EoE until she was in her late 20s. She was undiagnosed but was given prednisone for her problems. Now she wonders if she should get a DEXA scan. [10:15] Holly hopes the listeners will learn something and advocate for themselves or for their children. [10:52] If a patient is concerned about their bone mineral density, talking to your PCP is a perfect place to start. They can discuss the risk factors and order a DEXA scan and interpret it, if needed. [11:11] If osteoporosis is diagnosed, you should see an endocrinologist, specifically to discuss therapy, including medications called bisphosphonates. [11:36] From an EoE perspective, patients can talk to their gastroenterologist about what bone mineral density risk factors may be and if multiple risk factors exist. Gastroenterologists are also more than capable of ordering DEXA scans and helping their patients along that journey. [11:53] A DEXA scan is typically the way to measure bone mineral density. It's low radiation, it's easy, it's fast, and relatively inexpensive. [12:10] It's also useful in following up over time in response to different interventions, whether or not that's stopping medications or starting medications. [12:30] Dr. Henderson co-authored a paper in the Journal of Pediatric Gastroenterology and Nutrition, called “Prevalence and Predictors of Compromised Bone Mineral Density in Pediatric Eosinophilic Esophagitis.” The study looked at potential variables. [12:59] The researchers were looking at chronic systemic steroid use. They thought it was an issue in their patients, especially patients with multiple atopic diseases like asthma, eczema, and allergic rhinitis. That's where the study started. [13:22] Over the years, proton pump inhibitors have become more ubiquitous, and more research has come out. The study tried to find out if this was an issue or not. There weren't any guidelines for following these patients, as it was a retrospective study. [13:42] At the time, Dr. Henderson was at a large institution with a huge EoE population. She saw that she could do a study and gather a lot of information on a large population of patients. Studies like this are the start of figuring out the guidelines for the future. [14:34] Dr. Henderson wanted to determine whether pediatric patients with EoE had a lower-than-expected bone mineral density, compared to their peers. [14:44] Then, if there were deficits, she wanted to determine where they were more pronounced. Were they more pronounced in certain subgroups of patients with EoE? [14:59] Were they patients with an elemental diet? Patients with an elimination diet? Were they patients on steroids or PPIs? Were they patients with multiple atopic diseases? Is low bone mineral density just a manifestation of their disease processes? [15:14] Do patients with active EoE have a greater propensity to have low bone mineral density? The study was diving into see what the potential risk factors are for this patient population. [15:45] The study was a retrospective chart review. They looked at patients aged 3 to 21. You can't do a DEXA scan on a younger patient, and 21 is when people leave pediatrics. [16:03] These were all patients who had the diagnosis of EoE and were seen at Cincinnati Children's in the period between 2014 and 2017. That period enabled full ability for chart review. Then they looked at the patients who had DEXA scans. [16:20] They did a manual chart review of all of the patients and tried to tease out what the potential exposures were. They looked at demographics, age, sex, the age of the diagnosis of EoE, medications used, such as PPIs, and all different swallowed steroids. [16:44] They got as complete a dietary history as they could: whether or not patients were on an elemental diet, whether that was a full elemental diet, whether they were on a five-food, six-food, or cow's milk elimination diet. [16:58] They teased out as much as they could. One of the limitations of a retrospective chart review is that you can't get some of the details, compared to doing a prospective study. For example, they couldn't tease out the dosing or length of therapy, as they would have liked. [17:19] They classified those exposures as whether or not the patient was ever exposed to those medications, whether or not they were taking them at the time of the DEXA scan, or if they had been exposed within the year before the DEXA scan. [17:40] They also looked at whether the patients had other comorbid atopic disorders, to see if those played a role, as well. [18:03] The study found that there was a slightly lower-than-expected bone mineral density in the patients. The score was -0.55, lower than average but not diagnostic of a low bone mineral density, which would be -2 or below. [18:27] There were 23 patients with low bone mineral density scores of -2 or below. That was 8.6% of the study patients. Typically, only 2.5% of the population would have that score. It was hard to tease out the specific risk factors in a small population of 23. [18:57] They looked at what the specific risk factors were that were associated with low bone mineral density, or bone mineral density in general. [19:12] After moving from Colorado, Holly has transferred to a new care team, and doctors wanted her baseline Vitamin D and Calcium levels. No one had ever tested that on her before. Dr. Henderson says it's hard because there's nothing published on what to do. [19:58] The biggest surprise in the study was that swallowed steroids, or even combined steroid exposure, didn't have any effect on bone mineral density. That was reassuring, in light of what is known about glucocorticoid use. [20:16] The impact of PPI use was interesting. The study found that any lifetime use of PPIs did seem to decrease bone mineral density. It was difficult to tease out the dosing and the time that a patient was on PPIs. [20:34] Dr. Henderson thinks that any lifetime use of PPIs is more of a representation of their cumulative use of PPIs. At the time of the study, from 2014 to 2017, PPIs were still very much first-line therapy for EoE; 97% of the study patients had taken PPIs at some time. [21:02] There are so many more options now for therapy when a patient has a new diagnosis of EoE, especially with dupilumab now being an option. [21:11] Dr. Henderson speaks of patients who started on PPIs and have stayed on them for years. This study allows her to question whether we need to continue patients on PPIs. When do we discuss weaning patients off PPIs, if appropriate? [22:05] Ryan says these podcasts are a great opportunity for the community at large and also for the hosts. He just wrote himself a note to ask his endocrinologist about coming off PPIs. [22:43] Dr. Henderson says that glucocorticoid use is a known risk factor for low bone mineral density and osteoporosis. In the asthma population, inhaled steroids can slightly decrease someone's growth potential while the patient is taking them. [23:10] From those two facts, it was thought that swallowed steroids would have a similar effect. But since they're swallowed and not systemic, maybe things are different. [23:23] It was reassuring to Dr. Henderson that what her study found was that the swallowed steroid didn't affect bone mineral density. There was one other study that found that swallowed steroids for EoE did not affect someone's height. [23:51] Dr. Henderson clarifies that glucocorticoids include systemic steroids like prednisone and hydrocortisone. [23:57] Based on Dr. Henderson's retrospective study, fluticasone as a swallowed steroid did not affect bone mineral density. It was hard to tease out the dosing, but the cumulative use did not seem to result in a deficit for bone mineral density. [24:16] Holly shared that when she tells a family of a child she works with that the child's gastroenterologist will likely recommend steroids, she will now give them the two papers Dr. Henderson mentioned. There are different types of steroids. The average person doesn't know the difference. [25:15] Dr. Henderson thinks that for patients who have multiple risk factors for low bone mineral density, it is reasonable to have a conversation about bone health with their gastroenterologist to see whether or not a DEXA scan would be worth it. [25:56] If low bone mineral density is found, that needs to be followed up on. [26:03] There are no great guidelines, but this study is a good start on what these potential risk factors are. We need some more prospective studies to look at these risk factors in more detail than Dr. Henderson's team teased out in this retrospective study. [26:23] Dr. Henderson tells how important it is for patients to participate in prospective longitudinal studies for developing future guidelines. [26:34] Holly points out that a lot of patients are on restrictive diets. It's important to think about the whole picture if you are starting a medication or an elimination, or a restricted diet. You have to think about the impact on your body, overall. [27:11] People don't think of dietary therapy as medication, but it has risks and benefits involved, like a medication. [27:50] Dr. Henderson says, in general, lifestyle management is the best strategy for managing bone health. Stay as active as you can with weight-bearing exercises and eating a well-balanced diet. If you are on a restrictive diet, make sure it's well-balanced. [28:12] Dr. Henderson says a lot of our patients have feeding disorders, so they see feeding specialists like Holly. A balanced diet is hard when kids are very selective in their eating habits. [29:10] Dr. Henderson says calcium and Vitamin D are the first steps in how we treat patients with low bone mineral density. A patient who is struggling with osteoporosis needs to discuss it with their endocrinologist for medications beyond supplementation. [29:31] Ryan reminds listeners who are patients always to consult with their medical team. Don't go changing anything up just because of what we're talking about here. Ask your care team some good questions. [29:47] Dr. Henderson would like families to be aware, first, that some patients with EoE will have bone mineral density loss, especially if they are on PPIs and restrictive diets. They should start having those discussions with their providers. [30:04] Second, Dr. Henderson would like families to be reassured that swallowed steroids and combined steroid exposure didn't have an impact on bone mineral density. Everyone can take that away from today's chat. [30:18] Lastly, Dr. Henderson gives another plug for patient participation in prospective studies, if they're presented with the opportunity. It's super important to be able to gather more information and make guidelines better for our patients. [30:35] Holly thanks Dr. Henderson for coming on Real Talk — Eosinophilic Diseases and sharing her insights on bone mineral density, and supporting patients in Maine. [30:57] Dr. Henderson will continue to focus on the clinical side. She loves doing outreach clinics in rural Maine. It's rewarding, getting to meet all of these patients and taking care of patients who would otherwise have to travel hours to see a provider. [32:01] Ryan thinks the listeners got a lot out of this. For our listeners who would like to learn more about eosinophilic disorders, please visit APFED.org and check out the links in the show notes. [32:11] If you're looking to find specialists who treat eosinophilic disorders, we encourage you to use APFED's Specialist Finder at APFED.org/specialist. [32:19] If you'd like to connect with others impacted by eosinophilic diseases, please join APFED's online community on the Inspire Network at APFED.org/connections. [32:28] Ryan thanks Dr. Henderson for joining us today for this great conversation. Holly also thanks APFED's Education Partners Bristol Myers Squibb, Sanofi, Regeneron, and Takeda for supporting this episode. Mentioned in This Episode: Anna Henderson, MD, a pediatric gastroenterologist at Northern Light Health in Maine Cincinnati Children's “Prevalence and Predictors of Compromised Bone Mineral Density in Pediatric Eosinophilic Esophagitis.” Journal of Pediatric Gastroenterology and Nutrition APFED on YouTube, Twitter, Facebook, Pinterest, Instagram Real Talk: Eosinophilic Diseases Podcast apfed.org/specialist apfed.org/connections Education Partners: This episode of APFED's podcast is brought to you thanks to the support of Bristol Myers Squibb, Sanofi, Regeneron, and Takeda. Tweetables: “DEXA scan stands for dual-energy X-ray absorptiometry scan. It's a type of X-ray where a patient lies down for 10 to 30 minutes. A machine scans over their bones. Typically, we're most interested in the lumbar spine and hip bones.” — Anna Henderson, MD “We wondered whether or not all of those steroids and those combined risks even put our EoE population at risk for low bone mineral density. There's not a lot published in that area.” — Anna Henderson, MD “If a patient is worried [about their bone mineral density], their PCP is a perfect place to start for that. They're more than capable of discussing the risk factors specific for that patient, ordering a DEXA scan, and interpreting it if need be.” — Anna Henderson, MD “I think we need some more prospective studies to look at these risk factors in a little bit more detail than we were able to tease out in our retrospective review.” — Anna Henderson, MD “Just another plug for the participation in prospective studies, if you're presented with the opportunity. It's super important to be able to gather more information and to be able to make guidelines better for our patients about these risks.” — Anna Henderson, MD
Feeling burned out as the school year ends? You're not alone. In this episode, we're diving into the tough(but important) question many school counselors ask themselves: Is it time to move on? Summer break gives you the space to reflect, and this conversation offers support and clarity as you sort through the weight of burnout and consider what's next.We'll walk through practical questions to ask yourself, common scenarios that lead counselors to consider a change, and how to identify what you truly want in your career. Plus, if you're not ready to leave but know something needs to shift, we'll explore what changes could make your current role more sustainable. Whether you're staying or stepping away, this High School Counseling Conversations listener-favorite episode is here to help you move forward with purpose.Resources Mentioned: Clique Collaborative MembershipPodcast: The Lazy Genius- Episode 368: My Playbook for a Lazy Genius SummerResearch Article: School Counselors' Work-Related Rumination as a Predictor of Burnout, Turnover Intentions, Job Satisfaction, and Work Engagement by Mullen, Backer, Chae, and LiPodcast: Episode 101, Navigating Adult Friendships in The Workplace with Blake BlankenbeclerPodcast: Episode 98, What Should You Do if an Administrator Isn't Acknowledging the Value of Your Work?Podcast: Episode 77, What it Looks Like to Implement MTSS In a High School Setting with Dr. Jake Olsen and Dr. Peg DonohuePodcast: Episode 60, Setting Boundaries with Others and Managing Expectations Around BurnoutPodcast: Episode 45, 4 Different Caseload Model Types (Plus My Honest Thoughts on Them)Leave your review for School Counseling Conversations on Apple PodcastsConnect with Lauren:Sign up for the free, 3-day prep for High School Counseling Job Interviews https://counselorclique.com/interviewsVisit my TpT store https://counselorclique.com/shopSend me a DM on Instagram @counselorclique https://instagram.com/counselorcliqueFollow me on Facebook https://facebook.com/counselorcliqueSend me an email mailto:lauren@counselorclique.comJoin the Clique Collaborative
Pentagon pizza predictor full 2236 Mon, 16 Jun 2025 18:02:03 +0000 HCwLgQGA1YBGL7ujN4RIDiQ9olOeprGK news MIDDAY with JAYME & WIER news Pentagon pizza predictor From local news & politics, to what's trending, sports & personal stories...MIDDAY with JAYME & WIER will get you through the middle of your day! © 2025 Audacy, Inc. News False https://player.amperwavepodcasting.com?feed-link=https%3A%2F%2Frss.a
Did we mention that we'd won the Scottish Cup? Welcome to Episode 238 of the show as the three of us look back over the latest news coming out of Pittodrie this week, mainly focussing in on our newest signings, Emmanual Gyamfi & Kusini Yengi before we then look back at our season predictor and check out just how little we know about football after all! Become a paid subscriber over at abzfootballpodcast.com Follow us on our social media channels:- Twitter - @AbzPodcast Facebook - @ABZFootballPodcast Instagram - @abzfootballpodcast
GLP-1 receptor agonists have changed the landscape of obesity treatment, offering levels of weight loss once thought unattainable without surgery. But what happens after the weight is lost? And can we really talk about success without talking about maintenance? While much of the public discourse fixates on dramatic weight loss numbers, the harder question is what comes next. Can lifestyle interventions alone sustain weight loss after GLP-1 cessation? How do metabolic adaptations and behavioral relapse factor in? And what does the data actually show about relapse rates, nutritional adequacy, and lean mass preservation when using these medications? In this episode, Danny sits down with Tara Schmidt, dietitian at the Mayo Clinic, to examine the intersection of pharmacology and behavior in long-term weight management. Tara Schmidt is a registered dietitian and an instructor of nutrition at Mayo Clinic. As the lead dietitian for the Mayo Clinic Diet, she provides guidance rooted in evidence-based principles. She hosts the Mayo Clinic On Nutrition podcast and co-authored The Mayo Clinic Diet: Weight Loss Medications Edition. Timestamps [05:17] Understanding weight loss maintenance [08:44] Defining success in weight loss maintenance [11:54] Predictors of maintenance: self-monitoring and behavioral strategies [23:37] Pharmacological interventions: GLP-1 receptor agonists [31:06] Dietary considerations for those taking GLP-1 RAs [37:07] Addressing misconceptions about weight loss drugs [42:48] Final thoughts and takeaways [48:49] Key ideas (Premium-only) Links/Resources Subscribe to Sigma Nutrition Premium Go to episode page Join the Sigma email newsletter for free Enroll in the next cohort of our Applied Nutrition Literacy course Visit sigmanutrition.com
In this episode, Dr. Rena Malik, MD is joined by Dr. Lauren F. Streicher to demystify perimenopause and menopause, exploring their symptoms, hormonal fluctuations, and evidence-based treatments. They discuss managing common concerns such as sleep disruption, weight gain, hair loss, and changes in sexual health—including practical advice on hormone therapy, non-hormonal options, and relationship dynamics during this transition. Become a Member to Receive Exclusive Content: renamalik.supercast.com Schedule an appointment with me: https://www.renamalikmd.com/appointments ▶️Chapters: 00:00:00 Introduction 00:01:40 Menopause Myths & Hysteria 00:04:00 Perimenopause Physiology Explained 00:06:04 Hormone Tracking & Misconceptions 00:09:40 Recognizing Perimenopause Symptoms 00:12:55 Predictors of Menopause Timing 00:14:45 Managing Perimenopausal Symptoms 00:17:50 Cognitive Changes & Brain Fog 00:23:10 Weight Gain & Metabolism 00:25:50 Hair Loss & Unproven Supplements 00:31:45 Non-Hormonal Treatments Options 00:37:50 Relationship & Sexual Changes 00:41:00 Treating Genital Urinary Symptoms 00:44:55 Orgasm Changes and Vibrators 00:52:30 Oral Medications for Arousal Stay connected with Dr. Lauren Streicher on social media for daily insights and updates. Don't miss out—follow her now and check out these links! INSTAGRAM - https://www.instagram.com/drstreich/?hl=en X - https://x.com/DrStreicher FACEBOOK - https://www.facebook.com/DrStreicher/ YOUTUBE - https://www.youtube.com/@DrStreicherTV/ WEBSITE - https://www.drstreicher.com/ Let's Connect!: WEBSITE: http://www.renamalikmd.com YOUTUBE: https://www.youtube.com/@RenaMalikMD INSTAGRAM: http://www.instagram.com/RenaMalikMD TWITTER: http://twitter.com/RenaMalikMD FACEBOOK: https://www.facebook.com/RenaMalikMD/ LINKEDIN: https://www.linkedin.com/in/renadmalik PINTEREST: https://www.pinterest.com/renamalikmd/ TIKTOK: https://www.tiktok.com/RenaMalikMD ------------------------------------------------------ DISCLAIMER: This podcast is purely educational and does not constitute medical advice. The content of this podcast is my personal opinion, and not that of my employer(s). Use of this information is at your own risk. Rena Malik, M.D. will not assume any liability for any direct or indirect losses or damages that may result from the use of information contained in this podcast including but not limited to economic loss, injury, illness or death. Learn more about your ad choices. Visit megaphone.fm/adchoices
On this week's episode of the WHOOP Podcast, WHOOP Global Head of Human Performance Principal Scientist, Dr. Kristen Holmes, sits down with WHOOP Senior Scientist Dr. Bill von Hippel to discuss the science behind stress and sleep and its impact on performance. Dr. Bill von Hippel is a scientist, author, and renowned social psychologist and evolutionary specialist. In today's episode, Dr. Holmes and Dr. von Hippel discuss cardiac responses to threats and challenges and the core 4 circadian behaviors that help sleep consistency. (00:36) Intro to Cardiac Responses and Daily Threats and Challenges(03:08) Using WHOOP to Conduct Studies(09:09) Stress Monitor: Understanding Stress vs Challenge(11:10) Stress + Sleep Data on Shiftworkers(23:27) Low Fit vs High Fit: Use Case for Strain Coach (32:26) Amplifying Effects of Exercise(37:18) HRV-CV as a Predictor of Strain Load(43:03) Behaviors That Improve Sleep(51:06) Core 4: Circadian Behaviors That Help Sleep Consistency(58:49) The Impacts of Social Jetlag(01:02:53) Negative Impacts of Oversleeping(01:07:2) High HRV Indications and HRV ImprovementsReferences:WHOOP Wear Frequency StudyShiftwork Biometric Analysis StudyDr. Bill von Hippel:LinkedInThe Social Paradox: Autonomy, Connection, and Why We Need Both to Find HappinessThe Social Leap: The New Evolutionary Science of Who We Are, Where We Come From, and What Makes Us HappySupport the showFollow WHOOP: www.whoop.com Trial WHOOP for Free Instagram TikTok YouTube X Facebook LinkedIn Follow Will Ahmed: Instagram X LinkedIn Follow Kristen Holmes: Instagram LinkedIn Follow Emily Capodilupo: LinkedIn
Will our marriage really last? That's the question most couples ask—whether they say it out loud or not. In this powerful episode, we unpack the top predictor of marital success based on brand-new research shared by Les Parrott at a recent marriage conference: perceived partner commitment. What does that mean, and how do you build it?We break down the difference between commitment busters and commitment builders—everything from separate bank accounts and secrets to road trips and red lipstick moments. We share insights from 30 years of marriage, including personal stories, scriptures, and the hard lessons we've learned the long way. Whether you're just starting out or decades in, this episode will encourage you to build the kind of marriage that lasts—one built on intentional, everyday commitment.
BUFFALO, NY — May 23, 2025 — A new #research paper was #published in Aging (Aging-US) Volume 17, Issue 4, on April 1, 2025, titled “Examining frailty phenotypes of community-dwelling older adults in Taiwan using the falls risk for older people in the community – Taiwan version (Tw-FROP-Com).” A research team led by first author Ya-Mei Tzeng and corresponding authors Yu-Tien Chang and Yaw-Wen Chang from the National Defense Medical Center studied older adults in Taiwan and found that unintentional weight loss is the most significant individual predictor of fall risk among the common signs of frailty. This finding highlights the importance of early detection and tailored interventions to reduce fall-related injuries among aging populations. Falls are a major cause of injury-related death in seniors, especially in low- and middle-income countries. In Taiwan, they rank as the second leading cause of accidental death among those aged 65 and older. The researchers evaluated five signs of frailty—weakness, slowness, exhaustion, low physical activity, and unintentional weight loss—using a locally adapted fall risk screening tool, Tw-FROP-Com. Frailty is a condition marked by reduced strength, stamina, and resilience, making older adults more vulnerable to accidents and illness. The study analyzed data from 375 older adults participating in a fall prevention program in Keelung City. Of these, 18.7% were classified as frail, and nearly one-third had experienced a fall in the past year. All five frailty signs were associated with increased fall risk, but statistical analysis showed that unintentional weight loss had the strongest association, even after adjusting for factors like age and previous falls. Rather than relying on a broad frailty label, this study found that analyzing each frailty feature individually provided more accurate predictions of fall risk. Weight loss, in particular, was also associated with conditions such as malnutrition, muscle decline, or chronic illness. “Treating frailty as five distinct components provided a more precise prediction of fall risk than using a dichotomous frailty measure (Yes/No).” The findings support the use of accessible screening tools like Tw-FROP-Com in everyday healthcare settings. Because it does not require complex equipment or physical testing, it can be widely applied to identify older adults at risk. Interventions such as nutritional support, physical activity, and weight monitoring can then be offered before a fall occurs. The researchers recommend that public health programs and healthcare providers focus on each specific frailty sign, especially unintentional weight loss, rather than relying only on overall frailty status. As the global population ages, targeted fall prevention strategies like these may help older adults live healthier, more independent lives. Paper DOI: https://doi.org/10.18632/aging.206231 Corresponding authors: Yu-Tien Chang – greengarden720925@gmail.com; Yaw-Wen Chang- yawwenc@office365.ndmctsgh.edu.tw Keywords: aging, frailty, fall risk, fried frailty criteria, older adults, Tw-FROP-Com Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, epigenetics, DNA methylation, diet, biological clock To learn more about the journal, please visit our website at https://www.Aging-US.com and connect with us on social media at: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Bluesky - https://bsky.app/profile/aging-us.bsky.social Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM
On this episode, after recapping the first game of the Eastern Conference finals between the Knicks and the Pacers we'll discuss SGA's MVP victory before we predict what Jaren Jackson Jr.'s upcoming contract extension will be.
In this 'Inbetweenie' episode of the Movement Logic podcast, Sarah delves into the widespread misinterpretation of a 2014 research study titled 'Ability to Sit and Rise from the Floor as a Predictor of All-Cause Mortality.' Popularly known as the Sitting Rising Test (SRT), the study has been sensationalized in the media and on social platforms, claiming that the ability (or inability) to get up from the floor without assistance can predict mortality. Sarah critiques the study's methodology, the pitfalls of its media representation, and the critical difference between correlation and causation. She also emphasizes the importance of proper interpretation to avoid fear-mongering and encourages training in strength and balance for overall health benefits.Get on our Wait List for the Bone Density Course!Follow us on Instagram @movementlogictutorials01:08 Overview of the Misinterpreted Study03:35 Details of the Sitting Rising Test (SRT)04:21 Methodology and Findings of the Study14:33 Critique of the Study's Methodology23:43 Misinterpretations and Media Hype29:17 Conclusion and Final ThoughtsReferences: Episode 15: 3! Easy! Rules! About! Research!Ability to sit and rise from the floor as a predictor of all-cause mortality(abstract)Conor O'Shea podcast: Taking Control of Your Pain Through MovementSRT Test on YouTubeDiscover Magazine: Simple Sitting Test Predicts How Long You'll Live
This episode is brought to you by State & Liberty, Blokes & Joi, Fatty15 and FLYKITT. Bbiochemist and biomolecular therapy expert Jay Spall joins us to unravel his transformative journey from spinal injury to becoming a leading figure in the world of biohacking and longevity. Jay shares groundbreaking insights into follistatin therapy, detailing its impressive effects on endurance, body composition, and overall well-being. His personal narrative, combined with scientific research and anecdotes, paints a vivid picture of how cutting-edge therapies can enhance human performance and extend the quality of life. Follow MiniCircle @minicircledna Follow Chase @chase_chewning ----- In this episode we discuss... (00:01) Introduction to Biochemical Therapy (10:07) Reclaiming Our Health Through (17:30) Hormone Optimization Therapies (32:09) Modern Progressive Interventions (42:28) Taking Healthcare Power Back by Our Choices (54:49) Neurological Therapy (01:07:45) Gene Therapy for Health and Longevity (01:14:55) How to Actually Measure Longevity (01:22:14) Maximizing Healthspan and Lifespan With Gene Therapy (01:31:09) Why Community Matters (01:36:05) Connecting With MiniCircle ----- Episode resources: Save 15% on the best-fitting men's clothes with code CHASE at https://www.StateAndLiberty.com Save 10% on any diagnostic labs with code CHASE at https://www.JoiAndBlokes.com Save an additional 15% on the 90-day starter kit of C15:0 essential fatty acid with code EVERFORWARD at https://www.Fatty15.com/everforward Never get jet lag again and save 15% with code CHASE at https://www.FLYKITT.com Watch and subscribe on YouTube Learn more at MiniCircle.io
ALLEGED FALSE RECORDING OF SHANNON SHARPE AND HOLLYWOOD GETTING FREAKY PROBALY FAKE AND LEAVE PEOPLE CHILDREN ALONG GRWON PEOPLE GRAB MY BOOK A CONVERSATION WITH ALEXANDRIA AUGUST CATCHPHRASE LEMONS AND PEACHES AND SOME TEA ON MY MANISH ASS WHAT WAS I THINKING
This week I'm talking with Dr. Maggie Sibley, a clinical psychologist and professor at the University of Washington School of Medicine. Dr. Sibley has spent over two decades studying ADHD, and is author or co-author of over 120 research papers on the topic. And she is the author of Parent-Teen Therapy for Executive Function Deficits and ADHD: Building Skills and Motivation. So recently, when I was working on the newsletter for the show, I came across an article about ADHD titled "Study describes fluctuations, remissions seen with ADHD,” and that felt like it was worth investigating more. While reading through the paper that was linked into the article I got to thinking, “hey, I'd love to ask some more questions about the findings in this paper,” and it occurred to me, hey, I can just reach out to the author of the paper for a conversation on the podcast. And so that's what today's show is all about, we dig into that paper, titled “Characteristics and Predictors of Fluctuating Attention-Deficit/Hyperactivity Disorder in the Multimodal Treatment of ADHD (MTA) Study” that looks into symptom fluctuation based on the a review of the Multimodal Treatment of ADHD (MTA) Study. We talk about how ADHD symptoms don't just disappear but actually tend to fluctuate — a lot more than many researchers expected. We also dive into why having more going on in life might actually make your ADHD symptoms less severe (or how that's just one interpretation of the results), how motivation works for us, and what it means to find your own “sweet spot” of structure. Plus, we get into the upcoming diagnostic guidelines for adult ADHD from the American Professional Society for ADHD and Related Disorders. This is definitely an episode you don't want to miss if you really enjoy the sciency side of things. Start Freedom today! Use code ADHD40 to get them 40% off a Freedom Yearly premium subscription! Listen to the Climbing the Walls podcast here! If you'd life to follow along on the show notes page you can find that at HackingYourADHD.com/222 YouTube Channel My Patreon This Episode's Top Tips ADHD symptoms don't always follow a straight decline or improvement. Symptoms can often fluctuate, sometimes improving for years and then intensifying again. Expect waves, not a straight line, and don't blame yourself when experiencing higher-than-normal symptoms. When you're in a phase where ADHD feels more manageable, that's a great time to try and take on more meaningful responsibilities — like work, school, or parenting — that can help create external structure and reinforce good patterns. While having more life demands (like a busy schedule, work responsibilities, or kids) can improve ADHD functioning by creating natural urgency and external motivators, it's also important to make sure it doesn't tip into overload. Not all clinicians are trained to recognize ADHD in adults, especially when childhood histories are murky. If your concerns are dismissed, it's okay — and important — to seek out a more knowledgeable provider. And on that note, look out for updated diagnostic and treatment guidelines for adult ADHD from APSARD (American Professional Society for ADHD and Related Disorders). While these guidelines won't change any of the diagnostic criteria in the DSM, they will help give clinicians clearer, evidence-based advice on how to apply them when evaluating ADHD in adults.
AABP Executive Director Dr. Fred Gingrich reviews a paper published in The Bovine Practitioner with the first author Madeline Mancke from Kansas State University. The objective of this study was to determine potential associations between Cardiac Troponin I (cTnI) serum concentration of cattle at initial bovine respiratory disease (BRD) treatment with the risk of retreatment or mortality at 60 days. BRD is the most significant disease in beef cattle and is a major cause of morbidity and mortality. Developing prognostic tools may be valuable for managing individual cases. cTnI is a protein that is released into the circulatory system after myocardial damage and may be useful as a biomarker for prognostication of BRD cases. Mancke walks through the results of the paper which demonstrated that 8/318 samples had high cTnI levels and animals with high cTn1 concentrations had a significantly greater probability of not finishing the 60-day post-enrollment period. Cattle with high cardiac troponin concentrations at initial BRD treatment were more likely to have negative clinical outcomes but, in this study, very few animals had high cTnI levels. Mancke provides information about potential future research opportunities to better manage BRD cases in the feedyard. The Bovine Practitioner is the peer-reviewed journal published by AABP. The journal publishes original research, case studies, review articles and case studies that are intended to provide information to the practicing cattle veterinarian. The journal is available open-access online and print volumes are available for purchase. There are no publication fees for authors and the peer review and submission process is managed online. Find the journal at this link. Evaluation of cardiac troponin I as a predictor of clinical outcomes in cattle treated for bovine respiratory disease (BRD) in commercial feedyards. Bov Pract. 2025;59(1), 24-28. https://doi.org/10.21423/bpj20259053
Vision Driven Health - Bible Verses, Healthy Food, Weight Loss
Hey Friend, Believe it or not, research has found that the top predictor of longevity and your propensity to chronic disease is the amount of skeletal muscle you have. I am doing this episode, one because I think the info is SUPER important for creating sustainable life long health, but also because I'm trying to amp myself up to get more consistent with my muscle building workouts. About a year ago I threw out my back to where I was in my bed for days and had to have friends come watch my boys. I'll share more about how that's progressed in the episode, but long story short, I'm in a place to finally start focusing on the kind of workouts I love - the kind that BUILD muscle. If you've never considered intentionally trying to build muscle, I'd LOVE for you to listen in. And if you already know the benefits or you kind of know it's a good thing, but haven't actively started building muscle, by the end of this episode, you'll learn how greatly beneficial skeletal muscle is for your long term health AND you'll have a few SIMPLE first steps to get you going. Enjoy! Robin *** Listen to the episode with my chiropractor, Ralph Winestock - Episode 32 - Coming into Alignment with God's Design. An Inside Look at Chiropractic Care Start building muscle with the SLAM workout app with a 14 day free trial - visiondrivenhealth.com/slam Get my free protein guides the 100g guide and the 20 protein packed recipes in 20 minutes guide at visiondrivenhealth.com/resources *** *** When you're ready, here are 4 ways I can support you in your health journey: 1. Grab my free 5 Day Sugar Fast Devotional In this 5 Day Devotional you have the opportunity to drop weight and sugar cravings while gaining a totally new approach to health that is grounded in Jesus. Download it here: https://madewellhealth.com/sugarfast 2. Join my free Facebook group In this group you'll have access to years of resources I've shared along with the new content I put out weekly. Additionally, you'll be in good company with fellow Jesus loving ladies looking to live a sustainable healthy lifestyle. Join us here: https://www.facebook.com/groups/RobinRhineMcD/ 3. Take the Healthy Cooking Made Easy Mini Course This short course will show you how to enjoy healthy cooking with confidence by saving time, cooking less, and loving what you make! Sign up here: https://go.madewellhealth.com/cooking 4. Work with Me Directly Whether it's joining my 6 week course, the Healthy Weight Loss Academy or getting 1-1 coaching, I am all about SIMPLIFYING healthy weight loss and providing the tools and resources you need to create healthy habits you'll keep by partnering with God and following my proven Sustainable Health process. For more info and to apply, click here: https://www.visiondrivenhealth.com/get-coaching
What Fresh Hell: Laughing in the Face of Motherhood | Parenting Tips From Funny Moms
"Maternal gatekeeping" usually shows up in pop culture as an overbearing, overprotective mother preventing everyone else from even touching the baby. But maternal gatekeeping is a multidimensional phenomenon that isn't as simple as anxious mothers needing complete control over their newborn's schedule. Here is what the studies on maternal gatekeeping say and how it can manifest in two-parent households. Amy and Margaret discuss: The three dimensions of the term "maternal gatekeeping" and what the original definition gets wrong The best predictors of maternal gatekeeping in a couple's dynamic The societal pressures that reinforce maternal gatekeeping Here are links to some of the resources mentioned in the episode: Miss Perceived podcast with Leah Ruppanner: Are Dads Being Shut Out of Childcare? Breaking Down the "Maternal Gate" Sarah J. Schoppe-Sullivan, et. al for Parenting Science and Practice Journal: Who are the Gatekeepers? Predictors of Maternal Gatekeeping Sarah M. Allen and Alan J. Hawkins for the Journal of Marriage and Family: Maternal Gatekeeping: Mothers' Beliefs and Behaviors That Inhibit Greater Father Involvement in Family Work We love the sponsors that make this show possible! You can always find all the special deals and codes for all our current sponsors on our website: https://www.whatfreshhellpodcast.com/p/promo-codes/ mom friends, funny moms, parenting advice, parenting experts, parenting tips, mothers, families, parenting skills, parenting strategies, parenting styles, busy moms, self-help for moms, manage kid's behavior, teenager, tween, child development, family activities, family fun, parent child relationship, decluttering, kid-friendly, invisible workload, default parent, emotional labor, cognitive labor, maternal gatekeeping Learn more about your ad choices. Visit podcastchoices.com/adchoices
Playing the Field Of 68's $15 build-your-team transfer game! Predicting where the top 10 uncommitted transfers will go! A college coach proposes two-way contracts to fix the portal?! Sign up here: https://underdogfantasy.com/ and deposit using code SLEEPERS to receive up to $1K in bonus credit + a free pick!
Episode SummaryI discuss the greatest predictor of your future success, and how you can regain control and steer this ship where you want it to go..Show Notes Pagejeffsanders.com/577a.Go Premium!Exclusive bonus episodes, 100% ad-free, full back catalog, and more!Free 7-Day Trial of 5 AM Miracle Premium.Perks from Our SponsorsHypnozio → Go to https://sponsr.is/hypnozio_5amMiracle and use my code 5AM15 to grab 15% off your first subscription with HypnozioListen Later → Get up to 25% extra free credits when purchasing $50 or moreTimeline → Get 10% off your order of Mitopure®.Learn More About The 5 AM MiracleThe 5 AM Miracle Podcast.Free Productivity Resources + Email Updates!Join The 5 AM Club!.The 5 AM Miracle BookAudiobook, Paperback, and Kindle.Connect on Social MediaLinkedIn • Facebook Group • Instagram.About Jeff SandersRead Jeff's Bio.Questions?Contact Jeff.© 5 AM Miracle Media, LLC.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
A magician spins a black top hat to show their audience it's empty. Then, with the wave of a wand and a few magic words, PRESTO: a snow white rabbit pokes its ears over the brim. Compared to sawing a person in half, pulling a rabbit out of a hat is a joyful bit of magic that entertainers have been doing for more than 200 years. But after the applause dies down, one is left wondering: where did the rabbit come from? And where did it go? Today, in honor of the Easter Bunny (who doesn't actually appear in this episode), we're pulling a handful of rabbit stories out of our proverbial hat. But be warned: these are dark tales of disappearing pets, occult eugenicists, and animal sacrifice. The secrets behind some magic tricks are more shocking than others. Featuring Nicole Cardoza, Gwyne Henke, Suzanne Loui, Sally Master, Ana DiMaria, Tanya Singer, and Meg Crane. Produced by Nate Hegyi, Marina Henke, Kate Dario, and Justine Paradis. For full credits, photos, and transcript, visit outsideinradio.org. SUPPORTTo share your questions and feedback with Outside/In, call the show's hotline and leave us a voicemail. The number is 1-844-GO-OTTER. No question is too serious or too silly.Outside/In is made possible with listener support. Click here to become a sustaining member of Outside/In. Follow Outside/In on Instagram or join our private discussion group on Facebook. LINKSJoin us for NHPR's 3rd Annual Climate Summit! The theme is “Healthy Connections,” and we've got a great lineup of speakers and breakout sessions PLUS a trivia night. And the best part? It's all FREE. Learn more and register here. Check out this video of magician and storyteller Nicole Cardoza performing for a group in Chicago in 2024. You can check out Gwyne Henke's childhood rabbit poetry on our website. Tanya Singer reported on the history of Project Angora for Tablet. You can also learn more about Helena Weinrauch and her blue sweater here. Read more about the history of pregnancy testing in this paper on Egyptian grain method, rabbit tests, and more, and in A Woman's Right to Know by Jesse Olszynko-Gryn, available as a free ebook from MIT Press.The story of Meg Crane's Predictor test can also be found in the excellent Designing Motherhood, a book and exhibit on human reproduction through the lens of design.Pagan Kennedy's New York Times article, which prompted Meg Crane to start sharing her story—and Pagan's follow-up, which does include Meg.
Outline00:00 - Intro01:07 - Early steps02:47 - Why control?05:20 - The move to the US07:40 - The first journal paper13:30 - What is backstepping?17:08 - Grad school25:10 - Stochastic stabilization29:53 - The interest in PDEs43:24 - Navier-Stokes equations52:12 - Hyperbolic PDEs and traffic models57:51 - Predictors for long delays1:08:14 - Extremum seeking1:27:14 - Safe control1:36:30 - Interplay between machine learning and control1:42:28 - Back to the roots: robust adaptive control1:50:50 - On service1:55:54 - AdviceLinksMiroslav's site: https://flyingv.ucsd.edu/Tuning functions paper: https://tinyurl.com/yznv6r9rP. Kokotović: https://tinyurl.com/mwmbm9yhSeparation and swapping: https://tinyurl.com/y4fre6t8Adaptive nonlinear stabilizers: https://tinyurl.com/4a9wmmvxKKK book: https://tinyurl.com/2kw2b4k6Stochastic nonlinear stabilization: https://tinyurl.com/4td3537aFollow-up with unknown covariance: https://tinyurl.com/4c4n7fd7Boundary state feedbacks for PIDEs: https://tinyurl.com/4e9y4tdrBoundary Control of PDEs: https://tinyurl.com/d8x38bmjStabilization of Navier–Stokes systems: https://tinyurl.com/4a8cbjemTraffic congestion control: https://tinyurl.com/525jphs5Delay compensation: https://tinyurl.com/5yz6uj9pNonlinear predictors for long delays: https://tinyurl.com/7wvce6vyStability of extremum seeking: https://tinyurl.com/mr5cvzd3Nash equilibrium seeking: https://tinyurl.com/yeywrysnInverse optimal safety filters: https://tinyurl.com/9dkrpvkkNeural operators for PDE control: https://tinyurl.com/5yynsp7vBode lecture: https://tinyurl.com/mp92cs9uCSM article: Support the showPodcast infoPodcast website: https://www.incontrolpodcast.com/Apple Podcasts: https://tinyurl.com/5n84j85jSpotify: https://tinyurl.com/4rwztj3cRSS: https://tinyurl.com/yc2fcv4yYoutube: https://tinyurl.com/bdbvhsj6Facebook: https://tinyurl.com/3z24yr43Twitter: https://twitter.com/IncontrolPInstagram: https://tinyurl.com/35cu4kr4Acknowledgments and sponsorsThis episode was supported by the National Centre of Competence in Research on «Dependable, ubiquitous automation» and the IFAC Activity fund. The podcast benefits from the help of an incredibly talented and passionate team. Special thanks to L. Seward, E. Cahard, F. Banis, F. Dörfler, J. Lygeros, ETH studio and mirrorlake . Music was composed by A New Element.
What are the three predictors of retirement happiness? Dr. Michael Finke, CFP® from the American College of Financial Services tells us what his research shows. He also shares his insights on the four percent rule for retirement withdrawals and whether there is anything we can do to stave off the effects of aging on our cognitive abilities. That's today on Your Money, Your Wealth podcast number 523 with Joe Anderson, CFP® and Big Al Clopine, CPA. Plus, Joe and Big Al do some retirement spitballing: can Jon in Pennsylvania retire early at age 56, and would it be better for him to take his pension monthly or as a lump sum? Steve and his wife in Colorado are 48 and 54 and have $3 million saved. When can they retire? Eager Eagle and his wife in Washington state have $2 million saved at ages 61 and 63. Can they retire next year? Free financial resources & episode transcript: https://bit.ly/ymyw-523 DOWNLOAD The Retirement Lifestyles Guide DOWNLOAD The Social Security Handbook WATCH: Social Security Basics You Need to Know: Common Social Security Questions Answered on YMYW TV WATCH/LISTEN: What's Your Retirement Income Style? ASK Joe & Big Al for your Retirement Spitball Analysis SCHEDULE your Free Financial Assessment SUBSCRIBE to YMYW on YouTube DOWNLOAD more free guides READ financial blogs WATCH educational videos SUBSCRIBE to the YMYW Newsletter
Who's to blame for the crisis of American masculinity? On the right, politicians tell men that they being oppressed by feminists and must reassert their manhood by supporting an authoritarian regime. And on the left, users of social media are often very irritating to people who write airport books. Where to find us: Peter's newsletterPeter's other podcast, 5-4Mike's other podcast, Maintenance PhaseSources:Conscientiousness as a Predictor of the Gender Gap in Academic AchievementGender Differences in Scholastic Achievement: A Meta-AnalysisEarly Childhood Behavior Problems and the Gender Gap in Educational Attainment in the United StatesWhere The Boys Aren'tThe gender achievement gap in grades and standardised testsThe State of Gender Equality for U.S. AdolescentsHighlights of women's earnings in 2023The gender gap in educational outcomes in NorwaySocial Influences And The Gender Gap In Disruptive BehaviorFamily Disadvantage and the Gender GapWhat might interrupt men's suicide?As Women Take Over a Male-Dominated Field, the Pay DropsThe Cost of CaringIs Your Child Ready for Kindergarten?Age of Entry to Kindergarten and Children's Academic AchievementThe Effect of Age at School Entry on Reading Achievement Scores Beyond the Pros and Cons of RedshirtingSelf- Control and the Developing BrainImportance of Sex Differences in Impulse Control and AddictionsIt is a myth that boys lag behind in brain developmentThanks to Mindseye for our theme song!
In this episode, I share a critical lesson we learned the hard way—why relying solely on past sales data to forecast inventory for seasonal products can be a big mistake. For the first three years of our brand, we experienced consistent growth, fueled by marketing, new SKUs, and the surge in demand during COVID. But what we didn't account for was the actual market demand beyond our own sales numbers. I break down the risks of over-relying on historical data, how we adjusted our approach, and what you can do to avoid the same mistake. ➡️ All my resources: https://www.andyisom.com/
My guest today is Ravi Gupta. Ravi is a Partner at Sequoia Capital and a host on Glue Guys, a podcast on the Colossus network that intersects business and sports. I wanted to have him back on Invest Like the Best to discuss his recent most recent blog post titled “AI or Die.” As both an investor and former Instacart operator and CFO, Ravi believes we're entering an era where the constraints that historically limited small teams are dissolving, creating unprecedented opportunities for those willing to embrace change aggressively. We discuss why traditional metrics of corporate success like headcount and process adherence may become liabilities, what it means to be a world-class reactor vs predictor, and how "magic per employee" and organizational agility will emerge as crucial measures of value creation. Please enjoy my conversation with Ravi Gupta. Subscribe to Colossus Review. For the full show notes, transcript, and links to mentioned content, check out the episode page here. ----- This episode is brought to you by Ramp. Ramp's mission is to help companies manage their spend in a way that reduces expenses and frees up time for teams to work on more valuable projects. Ramp is the fastest-growing FinTech company in history, and it's backed by more of my favorite past guests (at least 16 of them!) than probably any other company I'm aware of. Go to Ramp.com/invest to sign up for free and get a $250 welcome bonus. – This episode is brought to you by Ridgeline. Ridgeline has built a complete, real-time, modern operating system for investment managers. It handles trading, portfolio management, compliance, customer reporting, and much more through an all-in-one real-time cloud platform. I think this platform will become the standard for investment managers, and if you run an investing firm, I highly recommend you find time to speak with them. Head to ridgelineapps.com to learn more about the platform. – This episode is brought to you by AlphaSense. AlphaSense has completely transformed the research process with cutting-edge AI technology and a vast collection of top-tier, reliable business content. Imagine completing your research five to ten times faster with search that delivers the most relevant results, helping you make high-conviction decisions with confidence. Invest Like the Best listeners can get a free trial now at Alpha-Sense.com/Invest and experience firsthand how AlphaSense and Tegus help you make smarter decisions faster. ----- Editing and post-production work for this episode was provided by The Podcast Consultant (https://thepodcastconsultant.com). Show Notes: (00:00:00) Learn About Ramp, Ridgeline, & Alphasense (00:06:00) Introduction to 'AI or Die' Essay (00:06:29) Initial Reactions to AI Advancements (00:08:24) The Concept of 'AI or Die' (00:10:40) Adapting to Rapid Technological Change (00:12:02) Using AI for Real Work (00:13:58) Evaluating Company Agility and AI Integration (00:18:58) The Cost of Employees in the AI Era (00:25:36) AI's Impact on Business Strategy (00:36:55) Changing Perspectives on AI Models (00:37:50) The Importance of Context in AI (00:39:09) Optimism in the Age of AI (00:40:22) Predictors vs. Reactors (00:42:54) AI Tools in Business Operations (00:46:07) The Future of Small Teams and Efficiency (00:49:01) Investing in the AI Era (00:55:11) The Role of Board Members in AI Adoption (00:57:22) Embracing Change with Humility (00:59:17) The Ghost of Competition (01:05:04) Seizing the AI Opportunity