Podcasts about Genetic

Today we are featuring two articles that relate to moving genetics into mainstream healthcare. In our first segment, we discuss polygenic risk scores and the transition from research to clinical use. Our second segment focuses on hypermobility Ehlers Danlos Syndrome and the triaging of clinical referrals.    Segment 1: Readiness and leadership for the implementation of polygenic risk scores: Genetic healthcare providers' perspectives in the hereditary cancer context   Dr Rebecca Purvis is a post-doctoral researcher, genetic counsellor, and university lecturer and coordinator at The Peter MacCallum Cancer Centre and The University of Melbourne, Melbourne, Australia. Dr Purvis focuses on health services delivery, using implementation science to design and evaluate interventions in clinical genomics, risk assessment, and cancer prevention.   In this segment we discuss: - Why leadership and organizational readiness are critical to successful clinical implementation of polygenic risk scores (PRS). - How genetic counselors' communication skills position them as key leaders as PRS moves from research into practice. - Readiness factors healthcare systems should assess, including culture, resources, and implementation infrastructure. - Equity, standardization, and implementation science as essential tools for responsible and sustainable PRS adoption. Segment 2: A qualitative investigation of Ehlers-Danlos syndrome genetics triage   Kaycee Carbone is  a genetic counselor at Boston Children's Hospital in the Division of Genetics and Genomics as well as the Vascular Anomalies Center. Her clinical interests include connective tissue disorders, overgrowth conditions, and somatic and germline vascular anomaly conditions. She completed my M.S. in Genetic Counseling at the MGH Institute of Health Professions in 2023. The work she discusses here, "A qualitative investigation of Ehlers-Danlos syndrome genetics triage," was completed as part of a requirement for this graduate program.    In this segment we discuss: - Why genetics clinics vary widely in how they triage referrals for hypermobile Ehlers-Danlos syndrome (hEDS). - How rising awareness of hEDS has increased referral volume without clear guidelines for diagnosis and care. - The ethical and emotional challenges genetic counselors face when declining hEDS referrals. - The need for national guidelines and clearer care pathways to improve access and coordination for EDS patients. Would you like to nominate a JoGC article to be featured in the show? If so, please fill out this nomination submission form here. Multiple entries are encouraged including articles where you, your colleagues, or your friends are authors.   Stay tuned for the next new episode of DNA Dialogues! In the meantime, listen to all our episodes Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “DNA Dialogues”.    For more information about this episode visit dnadialogues.podbean.com, where you can also stream all episodes of the show. Check out the Journal of Genetic Counseling here for articles featured in this episode and others.    Any questions, episode ideas, guest pitches, or comments can be sent into DNADialoguesPodcast@gmail.com.    DNA Dialogues' team includes Jehannine Austin, Naomi Wagner, Khalida Liaquat, Kate Wilson and DNA Today's Kira Dineen. Our logo was designed by Ashlyn Enokian. Our current intern is Stephanie Schofield.

Send us a textIn this episode of the Incubator, Betsy Crouch and David McCulley interview Dr. Wendy Chung, a leader in clinical genetics and child health research. They discuss her journey into genomics, the challenges faced in her career as a physician scientist, the importance of early mentorship, and her research interests, particularly in congenital diaphragmatic hernia (CDH). Dr. Chung shares insights on the complexities of genetic disorders and the need for innovative approaches in treatment and diagnosis. She discusses her experiences with newborn screening and the evolution of genetic screening for rare diseases, emphasizing the importance of advocacy for children's health research. The conversation highlights the impact of patient stories in research and concludes with personal insights into family activities and the importance of maintaining a balance between work and personal life.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textHow seasonal changes in light and dietary unsaturated fats affect circadian rhythms in mammals.Topics Discussed:Evolutionary context of circadian rhythms: All organisms have adapted to Earth's 24-hour day for survival, with internal clocks slightly offset and adjusted by environmental cues.Molecular clock mechanism: Involves a feedback loop where proteins turn on/off genes, lasting ~24 hours, regulated by phosphorylation and degradation for timing precision.Genetic variations in sleep: Families with mutations in clock genes like PER2 cause extreme morning lark behavior, altering protein stability and period length by hours.Light entrainment: Morning light shortens human clocks (average 24.2 hours) to match 24-hour days; seasonal day length changes require gradual adjustments.Food & metabolic links: Seasonal food scarcity/abundance affects clock via glucose and fatty acids competing for protein modifications, as shown in diabetic mouse models.Role of unsaturated fats: Paper finds MUFA/PUFA ratios in diet alter phosphorylation of clock proteins, speeding or slowing adaptation to winter/summer light cycles in mice.Modern environmental impacts: Artificial light extends “daytime” signals, while constant food access erases seasonal patterns, contributing to obesity and diabetes risks.Jet lag & adaptations: Sudden time shifts mimic seasonal experiments; high-sugar/fat intake may phenocopy genetic effects to aid adjustment, though not recommended for health.Practical Takeaways:Expose yourself to morning natural light to help synchronize your internal clock and improve daily energy.Consume main meals during daylight hours and avoid late-night eating to align with natural metabolic rhythms.Limit evening screen time to reduce artificial blue light disrupting sleep onset.Consider varying diet seasonally, favoring diverse, whole foods to mimic natural availability patterns for better health.About the guest: Louis Ptacek, MD is a neurologist and professor at the University of California, San Francisco. He researches inherited neurological diseases and sleep traits, including genetic variations causing extreme early rising.Related Episode:M&M 237: Circadian Biology: Genetics, Behavior, Metabolism, Light, Oxygen & Melatonin | Joseph Takahashi*Not medical advice.Support the showAffiliates: Lumen device to optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts

Allergy Elimination • Increased Energy • Parasite Cleansing • Pain Relief • Physical Strengthening • Improved Respiration • Better Digestion • Sharper Thinking • Deeper Sleep • Straighter Posture • Stronger Immunity • Clearer Skin • Thicker Hair • Fewer Migraines • Clearer Boundaries • Healthier Relationships • Heightened Manifestation • Greater AbundanceBiofield tuning through DNA activation is an increasingly well-received form of energy healing capable of stimulating a self-healing potential in the human genetic blueprint.Check out this extraordinary testimonial by one of the luminaries in the field of frequency medicine …The Regenetics approach to sound healing honors the total bio-spiritual spectrum while focusing on healing as a transformative process of “wholing.”https://www.phoenixregenetics.org“Anyone with a desire to elevate their energetic and physical potential needs to understand Luckman's work and experience it for themselves.” —Dr. Julie TwoMoon“Both fascinating and an astounding, perhaps even world-changing theory.” —NEW DAWN“Luckman has succinctly and elegantly provided a comprehensible intellectual framework for understanding the profound role of DNA in healing and transformation.” —Brendan D. Murphy, author of THE GRAND ILLUSIONBenefits can range from allergy relief and greater energy, to more harmonious relationships and added abundance, to empowerment and renewed life purpose. Since DNA interfaces with all physical, mental, emotional and spiritual aspects of our being, the possibilities are limitless!Expand your concept of the possible by watching the videos below for a quick intro to the art and science of “ener-genetically” rewriting yourself with this “revolutionary” 4-stage Method:1️⃣ Potentiation Electromagnetic Repatterning2️⃣ Articulation Bioenergy Enhancement3️⃣ Elucidation Triune Activation4️⃣ Transcension Bioenergy Crystallization Thank you for subscribing. Leave a comment or share this episode.

Spiritual guides confirmed this week that the genetic changes are happening now! How does this happen? And how does this relate to awakening to the higher self?For a deep dive, read The Augmentation of Man, The Acquiescence of Humanity, chapter 4, available on Amazon at the following link. $19.99.https://www.amazon.com/Acquiescence-Humanity-Augmentation-Man/dp/173343500X/ref=sr_1_1?crid=IWFYALA9L3SO&dib=eyJ2IjoiMSJ9.oMdzwdPkl_s245toRnj-pw.mjlJjs3oSERIbWbaYnxWhz0Bhy0QAQVdjDY1H9Gr-7Q&dib_tag=se&keywords=the+augmentation+of+man+the+acquiescence+of+humanity&nsdOptOutParam=true&qid=1765677765&sprefix=the+augmentation+of+man+%2Caps%2C501&sr=8-1

More Proof News to Share! This time we are discussing color breed updates following the December 2025 genetic evaluations. The discussion focuses on the Jersey sires GORMAN and his dam GARLAND along with the new release Jersey GARDNER and Ayrshire JOCKO and includes exciting developments in the Guernsey and Brown Swiss programs. Tune in to hear more on the genetic advancements in the color breed portfolios and the importance of listening to producer feedback for continuous improvement.0:00 Introduction and Guest Welcome00:39 Trends in Colored Breeds Evaluations01:57 Spotlight on Jersey Bulls: GORMAN and GARLAND04:14 New Jersey Sires: GARDNER and MILFORD08:49 Jersey STyle Lineup: ADAM and CANADIAN CLUB12:38 Introducing New Ayrshire Bull: JOCKO13:54 Updates on Guernsey and Milking Shorthorn15:36 Brown Swiss Program Highlights19:13 STamina™ Program Insights23:51 Genetic Direction and Final Thoughts28:25 Conclusion and Farewell

As we know there is an elevated interest in wild turkey science within the turkey hunting community, we are working to bring you numerous updates and research summaries from the 13th National Wild Turkey Symposium in Kansas City, Missouri. This episode includes conversations with authors or presenters from papers included in the "Wild Turkey Genetics" session: "Role of kinship in sociality of female eastern wild turkeys" — Chamberlain et al. (https://wildlife.onlinelibrary.wiley.com/doi/10.1002/wsb.1630) "Genetic structuring and within-flock relatedness of eastern wild turkeys" — Watkins et al. (Presented by Chamberlain) (https://wildlife.onlinelibrary.wiley.com/doi/10.1002/wsb.1622) Additional guests include the NWTF's Ricky Lackey. While we were not able to sit down and have further conversations about the following paper that also was included in the session about wild turkey genetics, please check out the following research paper titled "Investigating the role of management decisions in subspecies hybridization across the wild turkey's range" — Beckman et al. (https://wildlife.onlinelibrary.wiley.com/doi/10.1002/wsb.1625) To view the full symposium agenda, visit www.wildturkeysymposium.org.

Episode 336 In an unlikely turn of events, orcas and dolphins have been observed teaming up - to hunt and kill massive chinook salmon in the pacific. Given that orcas sometimes prey on dolphins, what's going on? Despite the promising signs of cooperation between these two species, there may be something less heartwarming at play. We dig into the findings and discuss other surprising ways animals cooperate with each other. From schizophrenia to bipolar disease, autism to OCD, many mental conditions are classified into different categories. But in the largest study of its kind, it's been discovered that 14 different disorders fall into just five genetic groups. The finding could explain why people are often diagnosed with multiple psychiatric conditions at once - and bring comfort to those who are. Could it also help us find better treatments? Exploding stars might be to thank for our very existence. It's thought that supernovae may spew out the heavy elements required for the creation of planets and the emergence of life. A new model shows this is possible - and may help us figure out where to look next for alien life. Could this open up a new field of cosmic ecology? Plus, news of a strange new kind of star from the James Webb Telescope. Black hole stars may explain a running mystery about odd galaxies spotted by the telescope, called little red dots.  Hosted by Rowan Hooper and Penny Sarchet, with guests Alec Luhn, Michael Le Page and Alex Wilkins. To read more about these stories, visit https://www.newscientist.com/ Learn more about your ad choices. Visit megaphone.fm/adchoices

IGG testing, also known as Immunoglobulin G testing, is a method used in forensic science to identify individuals through the analysis of specific proteins found in blood. Immunoglobulin G (IgG) is a type of antibody produced by the immune system in response to foreign substances, such as bacteria or viruses. Each person's IgG profile is unique, similar to a genetic fingerprint, making it useful for identification purposes.In crime-solving, IGG testing involves collecting blood samples from crime scenes and comparing them to known samples, such as those taken from suspects or victims. The presence or absence of specific IgG antibodies in the samples can help forensic investigators establish links between individuals and crime scenes.Police use IGG testing to:Establish connections between suspects and crime scenes: By comparing the IgG profiles of blood samples found at a crime scene with those of suspects or victims, investigators can determine whether a particular individual was present at the scene.Exclude innocent suspects: If the IgG profile of a suspect does not match that of the blood found at the crime scene, it can help exclude them from the investigation.Identify unknown individuals: In cases where the identity of a suspect or victim is unknown, IGG testing can be used to narrow down potential matches based on blood samples collected from the scene.However, like any forensic technique, IGG testing also raises privacy concerns. Some of these concerns include:Informed consent: Collecting blood samples for IGG testing without the individual's consent may raise ethical questions about privacy and bodily autonomy.Genetic information: IgG profiles can reveal information about an individual's immune system, which is a form of genetic information. There are concerns about how this sensitive data is collected, stored, and used, especially in terms of potential discrimination or misuse.False positives and misinterpretation: While IGG testing can be a valuable tool in forensic investigations, there is always a risk of false positives or misinterpretation of results. This could lead to wrongful accusations or convictions if not carefully considered.Database security: As with any forensic database, there are concerns about the security of the information stored within it. Unauthorized access or breaches could compromise individuals' privacy and potentially lead to misuse of their data.Ever since the arrest of Bryan Kohberger a conviction has rested upon the shoulders of the DNA that was collected at the scene of the brutal quadruple homicide. However, there have been challenges to the process used to collect that DNA and some have even questioned the constitutionality of the process itself. In this episode we take a look at that argument and hear from several legal scholars about the process that was used to collect the DNA and how that evidence will or will not be used moving forward.(commercial at 9:40)to contact me:bobbycapucci@protonmail.comsource:Moscow murder suspect could mount constitutional challenge | Idaho StatesmanBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-moscow-murders-and-more--5852883/support.

Ciara is joined in Kilkenny by father and son All-Ireland winning duo, Richie Power Sr and Richie Power Jr to discuss their own successes, and the state of the GAA in rural communities.

Live at the Zenos Health Summit, I've presented on stage why 22 years of mortality research and 371 million data points prove that every disease pathway has its roots in the absence of oxygen and the specific raw materials your body needs to function. I've also exposed fallacies around genetically-inherited diseases, why lowering homocysteine is critical for cardiovascular health, and walked through Dana White's transformation from brittle hypertensive on three blood pressure medications to canceling his heart ablation procedure entirely. The big data doesn't lie, and neither does human physiology when you finally give what it needs. What would you do differently if you knew exactly what was shortening your life? CLICK HERE TO BECOME GARY'S VIP!: https://bit.ly/4ai0Xwg Thank you to our partners H2TABS: “ULTIMATE10” FOR 10% OFF: https://bit.ly/4hMNdgg BODYHEALTH: “ULTIMATE20” FOR 20% OFF: http://bit.ly/4e5IjsV BAJA GOLD: "ULTIMATE10" FOR 10% OFF: https://bit.ly/3WSBqUa COLD LIFE: THE ULTIMATE HUMAN PLUNGE: https://bit.ly/4eULUKp WHOOP: JOIN AND GET 1 FREE MONTH!: https://bit.ly/3VQ0nzW AION: “ULTIMATE10” FOR 10% OFF: https://bit.ly/4h6KHAD A-GAME: “ULTIMATE15” FOR 15% OFF: http://bit.ly/4kek1ij PEPTUAL: “TUH10” FOR 10% OFF: https://bit.ly/4mKxgcn CARAWAY: “ULTIMATE” FOR 10% OFF: https://bit.ly/3Q1VmkC HEALF: 10% OFF YOUR ORDER: https://bit.ly/41HJg6S RHO NUTRITION: “ULTIMATE15” FOR 15% OFF: https://bit.ly/44fFza0 GOPUFF: GET YOUR FAVORITE SNACK!: https://bit.ly/4obIFDCGENETIC METHYLATION TEST (UK ONLY): https://bit.ly/48QJJrk GENETIC TEST (USA ONLY): ⁠https://bit.ly/3Yg1Uk9 Watch  the “Ultimate Human Podcast” every Tuesday & Thursday at 9AM EST: YouTube: https://bit.ly/3RPQYX8 Podcasts: https://bit.ly/3RQftU0 Connect with Gary Brecka Instagram: https://bit.ly/3RPpnFs TikTok: https://bit.ly/4coJ8fo X: https://bit.ly/3Opc8tf Facebook: https://bit.ly/464VA1H LinkedIn: https://bit.ly/4hH7Ri2 Website: https://bit.ly/4eLDbdU Merch: https://bit.ly/4aBpOM1 Newsletter: https://bit.ly/47ejrws Ask Gary: https://bit.ly/3PEAJuG Timestamps 00:00 Intro of Show 03:34 Presence of Oxygen = Absence of Disease 13:15 The Methylation Pathway Chart 13:28 Fallacies on Genetically-Inherited Diseases 14:38 Attention “Overload” (not Deficit) Disorder 18:15 What Drives Anxiety (and Other Mental Illnesses)? 25:59 Inability to Break Down Homocysteine 27:39 Dana White's Transformation 35:48 Catecholamines as Waking Neurotransmitters 38:22 The Gut-Brain Connection 43:14 The Genesis of Disease 46:01 Insulin Resistance 47:17 Importance of Hydrogen in the Human Body 55:56 Gary's Morning Routine 57:55 Join the TUH VIP 1:02:49 Extended Life Expectancy = Absence of Processed Food 1:06:10 ADD & ADHD Causes and Treatments 1:15:15 Managing Oxygen 1:17:27 Should You Take NAD+? 1:21:07 Rapid Weight Loss is a Toxic Process The Ultimate Human with Gary Brecka Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user's own risk. The Content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of the Gladden Longevity Podcast, Dr. Jeffrey Gladden and Kashif Khan discuss the intersection of genetics, health, and longevity. Kashif shares his personal journey from illness to founding the DNA company, emphasizing the importance of personalized medicine and genetic testing. They explore the unique health challenges faced by women, the impact of trauma and stress on health, and the need for individualized approaches in biohacking. The conversation highlights the significance of understanding hormone metabolism and the role of genetics in parenting, ultimately advocating for a comprehensive analysis of health to achieve optimal outcomes.   For Audience ·       Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/ !    Takeaways ·        Genetics play a crucial role in understanding individual health. ·        Personalized medicine is essential for effective treatment. ·        Women face unique health challenges that are often overlooked. ·        Understanding hormone metabolism is key to preventing health issues. ·        Trauma and stress can significantly impact health outcomes. ·        Biohacking should be individualized, not one-size-fits-all. ·        Nervous system regulation is vital for overall health. ·        Genetic predispositions can reveal superpowers and vulnerabilities. ·        Parenting can be enhanced through understanding children's genetics. ·        Comprehensive analysis is necessary for accurate health assessments.     Chapters 00:00 Introduction to Kashif and His Journey 05:37 The Role of Genetics in Health 08:12 Understanding Individual Health Through Multiple Lenses 11:12 The Importance of Personalized Medicine 14:00 The Intersection of Genetics and Trauma 17:04 Navigating the Biohacking Landscape 19:54 The Impact of Stress and Anxiety on Health 22:59 Transforming Trauma into Superpowers 29:04 The Impact of Social Media on Identity 30:01 Understanding Genetic Potential in Children 32:32 Personalized Parenting Through Genetic Insights 38:39 Women's Health: A Neglected Area 41:25 Hormonal Health and Cancer Risks 47:32 The Precision of Hormonal Treatments   To learn more about Kashif: Email:  kash@kashkhanofficial.com Website: https://kashkhanofficial.com/   Reach out to us at:    Website: https://gladdenlongevity.com/     Facebook: https://www.facebook.com/Gladdenlongevity/    Instagram: https://www.instagram.com/gladdenlongevity/?hl=en     LinkedIn: https://www.linkedin.com/company/gladdenlongevity    YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw       Gladden Longevity Podcast Disclosures Production & Independence The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas. Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements. Medical Disclaimer The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content. The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options. Use of information from this podcast and any linked materials is at the listener's own risk. Podcast Guest Disclosures Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team. Sponsorships & Affiliate Disclosures To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes. We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented. Additional Note on Content Integrity All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.

IGG testing, also known as Immunoglobulin G testing, is a method used in forensic science to identify individuals through the analysis of specific proteins found in blood. Immunoglobulin G (IgG) is a type of antibody produced by the immune system in response to foreign substances, such as bacteria or viruses. Each person's IgG profile is unique, similar to a genetic fingerprint, making it useful for identification purposes.In crime-solving, IGG testing involves collecting blood samples from crime scenes and comparing them to known samples, such as those taken from suspects or victims. The presence or absence of specific IgG antibodies in the samples can help forensic investigators establish links between individuals and crime scenes.Police use IGG testing to:Establish connections between suspects and crime scenes: By comparing the IgG profiles of blood samples found at a crime scene with those of suspects or victims, investigators can determine whether a particular individual was present at the scene.Exclude innocent suspects: If the IgG profile of a suspect does not match that of the blood found at the crime scene, it can help exclude them from the investigation.Identify unknown individuals: In cases where the identity of a suspect or victim is unknown, IGG testing can be used to narrow down potential matches based on blood samples collected from the scene.However, like any forensic technique, IGG testing also raises privacy concerns. Some of these concerns include:Informed consent: Collecting blood samples for IGG testing without the individual's consent may raise ethical questions about privacy and bodily autonomy.Genetic information: IgG profiles can reveal information about an individual's immune system, which is a form of genetic information. There are concerns about how this sensitive data is collected, stored, and used, especially in terms of potential discrimination or misuse.False positives and misinterpretation: While IGG testing can be a valuable tool in forensic investigations, there is always a risk of false positives or misinterpretation of results. This could lead to wrongful accusations or convictions if not carefully considered.Database security: As with any forensic database, there are concerns about the security of the information stored within it. Unauthorized access or breaches could compromise individuals' privacy and potentially lead to misuse of their data.Ever since the arrest of Bryan Kohberger a conviction has rested upon the shoulders of the DNA that was collected at the scene of the brutal quadruple homicide. However, there have been challenges to the process used to collect that DNA and some have even questioned the constitutionality of the process itself. In this episode we take a look at that argument and hear from several legal scholars about the process that was used to collect the DNA and how that evidence will or will not be used moving forward.(commercial at 9:40)to contact me:bobbycapucci@protonmail.comsource:Moscow murder suspect could mount constitutional challenge | Idaho StatesmanBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-moscow-murders-and-more--5852883/support.

This episode with Dr. David McCarty-Caplan touches on so many profound and heartfelt areas, carried by the radical vulnerability, honesty, and compassion he brings to the conversation. David generously shares about his reunion with his Colombian birth family-- first on his own, and later with his children and partner. We explore how his kids embraced reunion and modeled openness, curiosity and love with his family, and how their presence and perspective helped guide and teach him throughout the process. David also reflects on his identity as a Jewish Colombian adoptee and his powerful work community building with and for Jewish adoptees of color.  Dr. David McCarty-Caplan BioDr. David McCarty-Caplan (PhD) is a researcher, educator, writer, and consultant whose work sits at the intersection of identity, belonging, and social justice. Born in Bogotá, Colombia and adopted into a white Jewish family in the United States, David's life has been shaped by questions of race, family, and home. These experiences continue to inform his passion for helping adoptees and their families navigate the complex layers of identity, racism, and connection that often accompany adoption. Drawing on his background as a social work researcher and educator, David brings both personal insight and professional rigor to his work with organizations, communities, and families. He is especially interested in how people and institutions can create spaces where all feel seen and valued. David lives in Los Angeles with his wife and their two children, ages 12 and 10. As a husband, father, and adoptee, he is continually exploring what it means to nurture belonging — in his family, in his work, and in the broader world.https://www.shadesofbelonging.com/Co-Hosts: Nari Baker & Robyn ParkMusic: Mike Marlatt & Paul GulledgeAudio Production: Frederico Soler FernándezArtwork: Dalhe KimListen on: iTunes & SpotifyInstagram: @laboroflovepodcastSupport via Venmo: @laboroflovepodcast

In this solo livestream episode, Jason Cavness walks small business owners through the HR laws you must follow when you have 49 or fewer employees. Jason draws from more than 30 years of HR experience, 25 years as a retired U.S. Army officer, and over a decade working with startups to explain complicated HR rules in a simple, practical way.  Jason covers what federal government actually requires, why most HR mistakes come from confusion rather than bad intent, and how ignoring even one rule can lead to fines, audits, lawsuits, and massive headaches for small business owners.  Using real examples, stories from his career, and questions from livestream viewers, Jason breaks down what every employer needs to know: overtime rules, payroll tax obligations, discrimination laws, onboarding requirements, union rules, ADA accommodations, pregnancy protections, military employment rights, OSHA issues, misclassification risks, and more. If you're a founder, small business owner, or early-stage startup leader, this episode gives you a straightforward roadmap for staying compliant and protecting your business before something goes wrong.  Topics Discussed • Why HR feels complicated  and why it really isn't  • The real reason most small businesses get fined  • Drug-Free Workplace Act and who it does and does not apply to  • Audio monitoring vs video monitoring rules  • Polygraph testing and the extremely rare cases where it's allowed  • Military employment rights and what employers must provide  • Workplace safety, chemical safety sheets, and OSHA basics • Employee rights to discuss wages, schedules, and working conditions • Equal Pay Act misunderstandings and why negotiation habits matter • Minimum wage, overtime, exempt vs non-exempt rules • Why you must pay overtime even when you tell someone not to work it • I-9 verification, E-Verify, and immigration compliance • Payroll tax responsibilities • ADA and reasonable accommodation requirements • Pregnancy discrimination and common employer mistakes • Genetic information discrimination and health insurance issues • Title VII Civil Rights Act protections • LGBTQ workplace protections  • Age discrimination rules and why age 40 is the legal threshold • COBRA continuation for companies offering health benefits  • Worker misclassification and how calling someone a contractor doesn't make them one • Why unions form and how employers accidentally trigger unionization • What CavnessHR is building to automate HR and prevent these problems Support CavnessHR CavnessHR is building an AI-native HR system for small businesses with 49 or fewer employees  automated compliance plus access to a dedicated HR Business Partner.  Invest on Wefunder: https://wefunder.com/cavnesshr Download 7 free eBooks based on The Jason Cavness Experience: https://www.buildcavnesshr.com/ebooks Join the Builders Club: https://www.buildcavnesshr.com/ Connect with Jason Cavness LinkedIn: https://www.linkedin.com/in/jasoncavness/ https://www.linkedin.com/in/jasoncavness Instagram: https://www.instagram.com/jasoncavness TikTok: https://www.tiktok.com/@jasoncavness Podcast: https://www.thejasoncavnesssexperience.com  

Mandioca todo mundo conhece, certo? Mas, você já comeu cacau? Não, não o chocolate, o cacau mesmo. E o Cupuaçu? Conversamos sobre a importância cultural, versatilidade e potencial tóxico desses alimentos tão caracterísico do norte do Brasil. Patronato do SciCast: 1. Patreon SciCast 2. Apoia.se/Scicast 3. Nos ajude via Pix também, chave: contato@scicast.com.br ou acesse o QRcode: Sua pequena contribuição ajuda o Portal Deviante a continuar divulgando Ciência! Contatos: contato@scicast.com.br https://twitter.com/scicastpodcast https://www.facebook.com/scicastpodcast https://www.instagram.com/PortalDeviante/ Fale conosco! E não esqueça de deixar o seu comentário na postagem desse episódio! Expediente: Produção Geral: Tarik Fernandes e André Trapani Equipe de Gravação: Tarik Fernandes, Marcelo de Matos, Gustavo Rebello, Lenin Machado, Daniela Andrade, Diego Squinello Citação ABNT: Scicast #672: Sabores e Tradições Amazônicas: Mandioca, Cacau e Cupuaçu. Locução: Tarik Fernandes, Gustavo Rebello, Lenin Machado, Daniela Andrade, Diego Squinello. [S.l.] Portal Deviante, 09/12/2025. Podcast. Disponível em: https://www.deviante.com.br/podcasts/scicast-672 Imagem de capa: https://brasilagosto.org/cupuacu/ Referências e Indicações EMBRAPA (Empresa Brasileira de Pesquisa Agropecuária). "Açaí: o fruto da Amazônia". Disponível em: https://www.embrapa.br/tema-acai SILVA, S. M. et al. "Características nutricionais e funcionais do açaí (Euterpe oleracea Mart.)". Revista Brasileira de Fruticultura, 2014. SEBRAE (Serviço Brasileiro de Apoio às Micro e Pequenas Empresas). "Cadeia produtiva do açaí no Brasil". Disponível em: https://www.sebrae.com.br/sites/PortalSebrae/ufs/pa/artigos/a-cadeia-produtiva-do-acai JUNQUEIRA, N. T. V.; ROCHA, F. S. "Botânica e fruticultura do açaí". Revista Brasileira de Fruticultura, 2016. CAVALCANTE, P. B. "Frutas comestíveis da Amazônia". Belém: Museu Paraense Emílio Goeldi, 2010. MUÑIZ-MIRET, N. et al. "Genetic diversity of Euterpe oleracea Mart. in the Amazon". Scientia Agricola, 1996. INSTITUTO SOCIOAMBIENTAL (ISA). "Povos e comunidades tradicionais da Amazônia". Disponível em: https://www.socioambiental.org Canal Rural: “Pará exporta mais de 61 mil toneladas de açaí por ano, aponta estudo” Disponível em: https://www.canalrural.com.br/agricultura/para-exporta-mais-de-61-mil-toneladas-de-acai-por-ano-aponta-estudo Agência Pará: “Dia do Açaí: Pará segue na liderança nacional com mais de 90% da produção brasileira” Disponível em: https://agenciapara.com.br/noticia/59374/dia-do-acai-para-segue-na-lideranca-nacional-com-mais-de-90-da-producao-brasileira Estado de Minas: “Açaí brasileiro vira febre fora do país e ganha o mundo” Disponível em: https://www.em.com.br/app/noticia/economia/2023/10/15/internas_economia%2C1576667/acai-brasileiro-vira-febre-fora-do-pais-e-ganha-o-mundo.shtml Acai Berry Market Set to Thrive at an Impressive 11.5% CAGR Disponível em: https://www.newstrail.com/acai-berry-market-set/ BARBOSA, A. P. et al. "Compostos bioativos do jambu: uma revisão". Revista Brasileira de Farmacognosia, 2016. SILVA, S. M. et al. "Propriedades medicinais e culinárias do jambu (Acmella oleracea)". Revista Brasileira de Plantas Medicinais, 2015. Sugestões de vídeos: A lenda da mandioca (recomendado para crianças): https://www.youtube.com/watch?v=zSBsJTSX3AE Sugestões de links: Sobre diferenciar mandioca brava e mansa: https://www.cpt.com.br/dicas-cursos-cpt/e-possivel-diferenciar-mandioca-brava-da-de-mesa https://www.embrapa.br/embrapa-no-cirio/jambu https://ainfo.cnptia.embrapa.br/digital/bitstream/item/56524/1/n12-etnocultivo-do-jambu-p.pdfSee omnystudio.com/listener for privacy information.

This week we are talking about Pancreatic cancer.  This is a type of cancer that begins as a growth of cells in the pancreas. The pancreas lies behind the lower part of the stomach. It makes enzymes that help digest food and hormones that help manage blood sugar. The most common type of pancreatic cancer is pancreatic ductal adenocarcinoma. This type begins in the cells that line the ducts that carry digestive enzymes out of the pancreas. Pancreatic cancer rarely is found at its early stages when the chance of curing it is greatest. This is because it often doesn't cause symptoms until after it has spread to other organs. Your health care team considers the extent of your pancreatic cancer when creating your treatment plan. Treatment options may include surgery, chemotherapy, radiation therapy or a mix of these. Pancreatic cancer often doesn't cause symptoms until the disease is advanced. When they happen, signs and symptoms of pancreatic cancer may include: Belly pain that spreads to the sides or back. Loss of appetite. Weight loss. Yellowing of the skin and the whites of the eyes, called jaundice. Light-colored or floating stools. Dark-colored urine. Itching. New diagnosis of diabetes or diabetes that's getting harder to control. Pain and swelling in an arm or leg, which might be caused by a blood clot. Tiredness or weakness. It's not clear what causes pancreatic cancer. Doctors have found some factors that might raise the risk of this type of cancer. These include smoking and having a family history of pancreatic cancer. Understanding the pancreas The pancreas is about 6 inches (15 centimeters) long and looks something like a pear lying on its side. It releases hormones, including insulin. These hormones help the body process the sugar in the foods you eat. The pancreas also makes digestive juices to help the body digest food and take in nutrients. How pancreatic cancer forms Pancreatic cancer happens when cells in the pancreas develop changes in their DNA. A cell's DNA holds the instructions that tell a cell what to do. In healthy cells, the instructions tell the cells to grow and multiply at a set rate. The cells die at a set time. In cancer cells, the changes give different instructions. The changes tell the cancer cells to make many more cells quickly. Cancer cells can keep living when healthy cells would die. This causes there to be too many cells. The cancer cells might form a mass called a tumor. The tumor can grow to invade and destroy healthy body tissue. In time, cancer cells can break away and spread to other parts of the body. Most pancreatic cancer begins in the cells that line the ducts of the pancreas. This type of cancer is called pancreatic ductal adenocarcinoma or pancreatic exocrine cancer. Less often, cancer can form in the hormone-producing cells or the neuroendocrine cells of the pancreas. These types of cancer are called pancreatic neuroendocrine tumors or pancreatic endocrine cancer. Risk factors Factors that might raise the risk of pancreatic cancer include: Smoking. Type 2 diabetes. Chronic inflammation of the pancreas, called pancreatitis. Family history of DNA changes that can increase cancer risk. These include changes in the BRCA2 gene, Lynch syndrome and familial atypical multiple mole melanoma (FAMMM) syndrome. Family history of pancreatic cancer. Obesity. Older age. Most people with pancreatic cancer are over 65. Drinking a lot of alcohol. As pancreatic cancer progresses, it can cause complications such as: Weight loss. People with pancreatic cancer might lose weight as the cancer uses more of the body's energy. Nausea and vomiting caused by cancer treatments or a cancer pressing on the stomach might make it hard to eat. Sometimes the body has trouble getting nutrients from food because the pancreas isn't making enough digestive juices. Jaundice. Pancreatic cancer that blocks the liver's bile duct can cause jaundice. Signs include yellowing of the skin and the whites of the eyes. Jaundice can cause dark-colored urine and pale-colored stools. Jaundice often occurs without belly pain. If the bile duct is blocked, a plastic or metal tube called a stent can be put inside it. The stent helps hold the bile duct open. This is done using a procedure called endoscopic retrograde cholangiopancreatography, also called ERCP. During ERCP, a health care professional puts a long tube with a tiny camera, called an endoscope, down the throat. The tube goes through the stomach and into the upper part of the small intestine. The health professional puts a dye into the pancreatic ducts and bile ducts through a small tube that fits through the endoscope. The dye helps the ducts show up on imaging tests. The health professional uses those images to place a stent at the right spot in the duct to help hold it open. Pain. A growing tumor may press on nerves in your abdomen, causing pain that can become severe. Pain medications can help you feel more comfortable. Treatments, such as radiation and chemotherapy, might help slow tumor growth and provide some pain relief. When medicines aren't helping, a health care professional might suggest a celiac plexus block. This procedure uses a needle to put alcohol into the nerves that control pain in the belly. The alcohol stops the nerves from sending pain signals to the brain. Bowel blockage. Pancreatic cancer can grow into or press on the first part of the small intestine, called the duodenum. This can block the flow of digested food from the stomach into the intestines. A health care professional might suggest putting a tube called a stent in the small intestine to hold it open. Sometimes, it might help to have surgery to place a feeding tube. Or surgery can attach the stomach to a lower part of the intestines where the cancer isn't causing a blockage. Prevention Screening for people with a high risk of pancreatic cancer Screening uses tests to look for signs of pancreatic cancer in people who don't have symptoms. It might be an option if you have a very high risk of pancreatic cancer. Your risk might be high if you have a strong family history of pancreatic cancer or if you have an inherited DNA change that increases the risk of cancer. Pancreatic cancer screening might involve imaging tests, such as MRI and ultrasound. These tests are generally repeated every year. The goal of screening is to find pancreatic cancer when it's small and most likely to be cured. Research is ongoing, so it's not yet clear whether screening can lower the risk of dying of pancreatic cancer. There are risks to screening. This includes the chance of finding something that requires surgery but later turns out to not be cancer. Talk about the benefits and risks of pancreatic cancer screening with your health care team. Together you can decide whether screening is right for you. Genetic testing for cancer risk If you have a family history of pancreatic cancer, discuss it with a health care professional. The health professional can review your family history and help you understand whether genetic testing might be right for you. Genetic testing can find DNA changes that run in families and increase the risk of cancer. If you're interested in genetic testing, you might be referred to a genetic counselor or other health care professional trained in genetics. Ways to lower risk You might reduce your risk of pancreatic cancer if you: Stop smoking. If you smoke, talk to a member of your health care team about ways to help you stop. These might include support groups, medicines and nicotine replacement therapy. Maintain a healthy weight. If you are at a healthy weight, work to maintain it. If you need to lose weight, aim for a slow, steady weight loss of 1 to 2 pounds (0.5 to 1 kilogram) a week. To help you lose weight, exercise most days of the week. Slowly increase the amount of exercise you get. Choose a diet rich in vegetables, fruit and whole grains with smaller portions.  (CREDITS: MAYO CLINIC)

Mandioca todo mundo conhece, certo? Mas, você já comeu cacau? Não, não o chocolate, o cacau mesmo. E o Cupuaçu? Conversamos sobre a importância cultural, versatilidade e potencial tóxico desses alimentos tão caracterísico do norte do Brasil. Patronato do SciCast: 1. Patreon SciCast 2. Apoia.se/Scicast 3. Nos ajude via Pix também, chave: contato@scicast.com.br ou acesse o QRcode: Sua pequena contribuição ajuda o Portal Deviante a continuar divulgando Ciência! Contatos: contato@scicast.com.br https://twitter.com/scicastpodcast https://www.facebook.com/scicastpodcast https://www.instagram.com/PortalDeviante/ Fale conosco! E não esqueça de deixar o seu comentário na postagem desse episódio! Expediente: Produção Geral: Tarik Fernandes e André Trapani Equipe de Gravação: Tarik Fernandes, Marcelo de Matos, Gustavo Rebello, Lenin Machado, Daniela Andrade, Diego Squinello Citação ABNT: Scicast #672: Sabores e Tradições Amazônicas: Mandioca, Cacau e Cupuaçu. Locução: Tarik Fernandes, Gustavo Rebello, Lenin Machado, Daniela Andrade, Diego Squinello. [S.l.] Portal Deviante, 09/12/2025. Podcast. Disponível em: https://www.deviante.com.br/podcasts/scicast-672 Imagem de capa:  https://brasilagosto.org/cupuacu/ Referências e Indicações EMBRAPA (Empresa Brasileira de Pesquisa Agropecuária). “Açaí: o fruto da Amazônia”. Disponível em: https://www.embrapa.br/tema-acai SILVA, S. M. et al. “Características nutricionais e funcionais do açaí (Euterpe oleracea Mart.)”. Revista Brasileira de Fruticultura, 2014. SEBRAE (Serviço Brasileiro de Apoio às Micro e Pequenas Empresas). “Cadeia produtiva do açaí no Brasil”. Disponível em: https://www.sebrae.com.br/sites/PortalSebrae/ufs/pa/artigos/a-cadeia-produtiva-do-acai JUNQUEIRA, N. T. V.; ROCHA, F. S. “Botânica e fruticultura do açaí”. Revista Brasileira de Fruticultura, 2016. CAVALCANTE, P. B. “Frutas comestíveis da Amazônia”. Belém: Museu Paraense Emílio Goeldi, 2010. MUÑIZ-MIRET, N. et al. “Genetic diversity of Euterpe oleracea Mart. in the Amazon”. Scientia Agricola, 1996. INSTITUTO SOCIOAMBIENTAL (ISA). “Povos e comunidades tradicionais da Amazônia”. Disponível em: https://www.socioambiental.org Canal Rural: “Pará exporta mais de 61 mil toneladas de açaí por ano, aponta estudo” Disponível em: https://www.canalrural.com.br/agricultura/para-exporta-mais-de-61-mil-toneladas-de-acai-por-ano-aponta-estudo Agência Pará: “Dia do Açaí: Pará segue na liderança nacional com mais de 90% da produção brasileira” Disponível em: https://agenciapara.com.br/noticia/59374/dia-do-acai-para-segue-na-lideranca-nacional-com-mais-de-90-da-producao-brasileira Estado de Minas: “Açaí brasileiro vira febre fora do país e ganha o mundo” Disponível em: https://www.em.com.br/app/noticia/economia/2023/10/15/internas_economia%2C1576667/acai-brasileiro-vira-febre-fora-do-pais-e-ganha-o-mundo.shtml Acai Berry Market Set to Thrive at an Impressive 11.5% CAGR Disponível em: https://www.newstrail.com/acai-berry-market-set/ BARBOSA, A. P. et al. “Compostos bioativos do jambu: uma revisão”. Revista Brasileira de Farmacognosia, 2016. SILVA, S. M. et al. “Propriedades medicinais e culinárias do jambu (Acmella oleracea)”. Revista Brasileira de Plantas Medicinais, 2015. Sugestões de vídeos: A lenda da mandioca (recomendado para crianças): https://www.youtube.com/watch?v=zSBsJTSX3AE Sugestões de links: Sobre diferenciar mandioca brava e mansa: https://www.cpt.com.br/dicas-cursos-cpt/e-possivel-diferenciar-mandioca-brava-da-de-mesa https://www.embrapa.br/embrapa-no-cirio/jambu https://ainfo.cnptia.embrapa.br/digital/bitstream/item/56524/1/n12-etnocultivo-do-jambu-p.pdf

Proof news is here! Following an exciting December 2025 Genetics Evaluation, we learn about industry-wide changes along with notable sires like GARZA, DOMINANCE and CAPTAIN and their impact on STgenetics and their customers. We dive into the specifics of the Proven sire list, Net Merit ranking and STgenetics Eco$ ranking and discuss a new group of Slick bulls along with the Legend™ Program and the recent success of STyle™ sires. Tune in to hear the latest trends in the industry, future directions in the genetic portfolio and much more!00:00 Introduction and Welcome00:40 Industry-Wide Changes and Trends02:12 Top Bulls in the Proven Sire List04:17 Focus on GARZA and DOMINANCE07:12 Net Merit Ranking Success09:20 Eco$ Ranking Explained10:59 New Slick Bulls12:33 Legend™ Program Expansion15:01 Genomic Young Sires Highlights17:19 International Highlights and Fall Show Season20:03 Excitement for the Future23:28 Conclusion and Farewell

Summary In this episode of the Future of Dermatology podcast, Dr. Faranak Kamangar chats with Soroush Aboutalebi about his personal skin journey with a genetic condition called congenital ichthyosiform erythroderma, and the importance of community support through Camp Wonder. They discuss the challenges of managing skin conditions, the significance of compounding in dermatology, and the transformative experiences at Camp Wonder that help children build confidence and connect with others facing similar challenges. The conversation also touches on the future of dermatology, including exciting innovations in treatments and the role of dermatologists in patient care. Learn more about Camp Wonder: https://www.csdf.org/ Takeaways - Soroush Aboutalebi shares his journey with congenital ichthyosiform erythroderma. - Managing a skin condition can be challenging but also empowering. - Compounding medications have become less accessible in recent years. - Camp Wonder provides a supportive environment for children with skin conditions. - Building confidence is a key benefit of attending Camp Wonder. - Dermatologists play a vital role in the care provided at Camp Wonder. - Involvement in Camp Wonder can be through volunteering or donations. - The future of dermatology holds promise with new treatments and technologies. - Genetic therapies are on the horizon for skin conditions. - Community support is essential for individuals with skin diseases.  Chapters 00:00 - Introduction to the Future of Dermatology Podcast 00:54 - Soroush Aboutalebi's Skin Journey 05:06 - The Importance of Compounding in Dermatology 08:08 - Camp Wonder: A Safe Haven for Kids with Skin Conditions 10:49 - Building Confidence Through Camp Experiences 13:46 - The Role of Dermatologists at Camp Wonder 16:16 - Getting Involved with Camp Wonder 20:14 - Future of Dermatology: Hope for New Treatments

Age-related Macular Degeneration (AMD) is the leading cause of irreversible blindness for those over 50. But what if we could predict and treat the most aggressive forms? Join John Stanley as he speaks with Professor Robyn Guymer, co-lead on a groundbreaking international study from the Centre for Eye Research. Discover how this research could lead to targeted, individualized treatments - taking a critical step toward controlling a condition that affects millions. Plus, learn the vital difference between needing reading glasses and a sight-threatening eye condition.See omnystudio.com/listener for privacy information.

News items read by Laura Kennedy include: Genetic study reveals long isolation of early humans in southern Africa (details)(details) Ancient DNA offers new clues about early cat domestication (details)(details) New findings explain why men and women were sacrificed differently in ancient China (details)(details) Excavation reveals traces of Tlatelolca people beneath Mexico City (details)

Send us a textDr. Katherine P Callahan, neonatologist and bioethicist at Children's Hospital of Philadelphia, discusses the complexity of genetic testing in neonatal care. While the NICU serves as a launch point for genetic technologies due to high prevalence of genetic disease, genetic information is often ambiguous or uncertain rather than straightforwardly diagnostic. Variants of uncertain significance represent just one challenge—even clearly pathogenic findings may have unclear implications for individual patients, as demonstrated when parents carry the same mutation as their severely affected child. Callahan emphasizes that genetic information poses "informational hazards" requiring careful consideration of psychological and ethical impacts. She advocates for acknowledging complexity, rethinking outcomes beyond traditional measures, and embracing shared decision-making rather than standardized approaches to genomic counseling. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Leigh Ann interviews Gracia Walker, co-founder of Broc Shot, a supplement focused on sulforaphane, a powerful compound found in cruciferous vegetables. They discuss the origin story behind Broc Shot, the science behind sulforaphane, its health benefits, and the importance of quality and sustainability in the supplement industry. Gracia shares the science behind the brand, particularly regarding the impact of sulforaphane on conditions like psoriasis and its role in detoxification and inflammation management. Their conversation also highlights Broc Shot's commitment to ethical practices and environmental sustainability.Product Discount Codes + Links2025 Holistic Holiday Gift Guide: HereHerbal Face Food: Website (Discount Code: LAL30)Prolon Fast-Mimicking Program: Website (Discount Link Gives 25% off) Healing Alchemy Membership: Learn MoreGuest InfoBroc Shot - Website (Use code LEIGHANN for 20% off)Broc Shot - InstagramRelated EpisodesPodcast Ep. 215: Wade Lightheart (Bioptimizers) - Magnesium, The Master Mineral & Why Most Magnesium Supplements Fall ShortPodcast Ep. 184: Karen Hurd - A Biochemist Dives Deep Into the Science of Detoxing at a Cellular Level, Debunking Common Detox MythsPodcast Ep. 162: Dr. Stephanie Peacock - Unmasking Mold: Mast Cell Activation, Nervous System, Detox & MoreWork w/Leigh AnnLearn: What is EVOX Therapy?Book: Schedule a Session or FREE Discovery CallMembership: What is The Healing Alchemy MembershipConnect w/Me & Learn MoreWebsiteInstagramTiktokYoutube

Genetic history of dog domestication Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, researchers explore the impact of domestication on dog genetics and behavior. In this episode, we cover: •[00:00] Introduction •[01:00] Greger Larson explains how the history of gene flow between dogs and their wild relatives differs from what we know about other domestic species. •[02:38] Audrey Lin finds that low levels of wolf ancestry are found in almost two thirds of dog breeds. •[04:18] Linus Girdland Flink documents evidence of two genetic wolves on a remote Scandinavian island that may have been under human control. •[06:13] Clément Car explores how the mating systems of free-ranging village dogs could provide insight into canine domestication •[07:43] Katia Bougiouri explains how she used a statistical method to improve ancient genomes and what her results reveal about the history of inbreeding in dogs. •[09:21] Lachie Scarsbrook explains how he used museum specimens to reconstruct the history of inbreeding in German Shepherd Dogs. •[11:10] Eleanor Raffan analyzes genetic data and owner-submitted behavioral questionaries from 1,343 golden retrievers. •[12:54] Kathryn Lord finds that genetic testing cannot accurately predict canine behaviors. •[14:25] Final thoughts and conclusion. About Our Guest: Greger Larson  Professor  University of Oxford Audrey Lin  Gerstner Postdoctoral Scholar American Museum of Natural History Linus Girdland Flink  Lecturer  University of Aberdeen Clément Car  Postdoctoral Researcher University of Gdańsk Katia Bougiouri  Postdoctoral Researcher University of Copenhagen Lachie Scarsbrook Postdoctoral Researcher University of Oxford, Ludwig Maximilian University of Munich Eleanor Raffan  University Associate Professor  University of Cambridge Kathryn Lord Postdoctoral fellow  University of Massachusetts Chan Medical School View related content here: https://www.pnas.org/doi/10.1073/pnas.2528616122 https://www.pnas.org/doi/10.1073/pnas.2421768122 https://www.pnas.org/doi/10.1073/pnas.2421759122 https://www.pnas.org/doi/10.1073/pnas.2421756122 https://www.pnas.org/doi/10.1073/pnas.2416980122 https://www.pnas.org/doi/10.1073/pnas.2421755122 https://www.pnas.org/doi/10.1073/pnas.2421757122 https://www.pnas.org/doi/10.1073/pnas.2421752122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast  Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter

Can a psychopath be a good person? And how do we spot dangerous people when they seem so charming? This holiday special brings you an in-depth answer to one of your most-asked questions with highlights from Dr. Kerry's interview with Tara Blair Ball about the Dark Triad Personality.  We explore why dangerous people don't look scary, how we underestimate predatory behavior through "positive projection," and the critical difference between niceness and kindness—especially important to remember during the holiday season. PODCAST EXTRA This week, there is no exclusive Podcast Extra interview. Instead, we're offering this special holiday edition to ALL Substack subscribers as our gift to you!  This is the perfect time to join our community. SPECIAL ANNOUNCEMENT All Substack paid subscribers now receive immediate access to the Toxic-Free Relationship Club, which includes: -Invitation to the monthly Q&A with Dr. Kerry -Quarterly club-wide events featuring narcissistic abuse experts -Weekly newsletter with exclusive insights Find the Substack newsletter and join the community here: https://substack.com/@breakingfreenarcabuse 

Send us a textHow dietary polyunsaturated fats, especially omega-6 from seed oils, influence inflammation & heart health.Topics Discussed:Polyunsaturated fatty acids (PUFAs): Omega-6 from seed oils like safflower and corn can convert to pro-inflammatory molecules, while omega-3s produce resolving ones; imbalance biases toward chronic inflammation.Inflammation regulation: Acute inflammation aids healing but requires active “on” and “off” signals from lipid mediators; chronic inflammation arises from excess omega-6, delaying resolution.Heart health & diet: High omega-6 diets worsen post-heart attack outcomes in mice by elevating pro-inflammatory lipids.Evolution & historical context: PUFAs are essential but naturally balanced in pre-industrial diets; modern processing skews ratios, contributing to diseases, as shown in early rat experiments needing minimal fats for survival.Aging & lifestyle factors: Excess omega-6 exacerbates inflammation in older mice; sleep, exercise, and balanced fats are crucial for metabolic health and enzyme function in processing lipids.Cannabis & omega-6 interaction: In mice on high omega-6 diets, CBD-rich cannabis smoke reaches the heart quickly, suppresses immune response, and weakens cardiac strain, unlike in balanced-diet controls.Genetic models: FAT-1 mice converting omega-6 to omega-3 show better healing and neuroprotection; FAT-2 mice doing the opposite exhibit liver fibrosis and metabolic issues, highlighting omega-6 excess harms.Practical Takeaways:Balance omega-6 and omega-3 intake by reducing seed oils in processed foods and increasing sources like fish or algae to support inflammation resolution and heart health.Monitor and adjust fat intake with age, as older individuals are more sensitive to omega-6 excess leading to immune dysregulation.Avoid combining high omega-6 diets with smoking, as it may impair immune and cardiac responses based on animal data.About the guest: Ganesh Halade, PhD is a cardiovascular scientist and associate professor at the University of South Florida Morsani College of Medicine.*Not medical advice.Support the showAffiliates: Lumen device to optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts

Have you ever thought about what it means to be anonymous?  Have you considered what it means that you can walk down the street or go to the grocery store or out to dinner without someone you've never met knowing your name, everything you've posted online, or your political leanings? Or when you go on a first date with someone, they'd walk in knowing your dating history, your political affiliations, your credit score or what groceries you buy? Advancements in facial recognition and a secretive startup could end privacy as we know it.  In this two-part conversation, New York Times Tech Reporter Kashmir Hill joins host Ron Steslow to discuss privacy, anonymity, facial recognition software and her book Your Face Belongs to Us: A Secretive Startup's Quest to End Privacy as We Know It. In part 1: (01:43 ) Ron and Kashmir discuss anonymity and privacy and the erosion of both in our daily lives  (00:00 ) Balancing convenience and privacy  (11:00) The origins of ClearviewAI  (13:30) Genetic determinism in the development of facial recognition  (18:20) Kashmir dives deep into the history of facial recognition software and how it developed.  (22:37) How Facebook crowdsourced training facial recognition technology (25:00) How much privacy should we have and who should be able to use facial recognition software?  Read Your Face Belongs to Us: https://bit.ly/49qsbQm Follow Ron and Kashmir  on X (formerly Twitter): https://twitter.com/RonSteslow https://twitter.com/kashhill Email your questions and thoughts to podcast@politicology.com or leave us a voicemail at ‪(202) 455-4558‬. Learn more about your ad choices. Visit megaphone.fm/adchoices

JP Dinnell talks about Discipline, Fasting, World War 2 Veterans, Serving with Jocko, and more. Get your free training from First In Nutrition: https://www.firstinnutrition.com/jppod More from JP Dinnell: https://www.jpdinnell.com/ Join the conversation on instagram JP Dinnell: http://instagram.com/jpdinnell/ Lucas Pinckard: https://www.instagram.com/lucaspinckard Bruiser Arms: https://www.instagram.com/bruiserarms Echelon Front: https://echelonfront.com/ Little Cattle Co: http://littlecattle.co On The Path Printing: https://www.instagram.com/onthepathprinting JP Dinnell is a former U.S. Navy SEAL and now a Leadership Instructor, Speaker and Strategic Advisor with Echelon Front, where he serves as Director of Experiential Leadership Training Programs. J.P. is also a pro team athlete and spokesperson for Origin Maine and Jocko Fuel, an American clothing and supplement company. J.P. has a signature Energy Drink flavor "Sour Apple Sniper" with Jocko Fuel. Jeremiah spent nearly a decade in the SEAL Teams with three combat deployments. Sent to the violent terrorist stronghold of Ar Ramadi, Iraq in 2006 with SEAL Team Three's Task Unit Bruiser, J.P. served as point man, machine gunner, and lead sniper for Delta Platoon opposite the American Sniper, Chris Kyle, who was in Charlie Platoon. For his leadership and courage under fire, JP was awarded a Silver Star, 2 Bronze Stars with Valor and the Army Commendation Medal with Valor helping Task Unit Bruiser to become the most highly decorated special operations unit of the Iraq War. He worked closely with SEAL Officers Jocko Willink, his Task Unit Commander, and Leif Babin, and was the driving force on many of the daring combat operations Jocko and Leif wrote about in Extreme Ownership. Upon his return, J.P. again worked directly for Jocko as a training instructor at Naval Special Warfare Group One Training Detachment, where he orchestrated realistic and challenging training scenarios for Special Operations Urban Combat training and Close Quarters Combat training to better prepare SEAL units for the real-world battlefield. He also served as a Combatives Instructor, Marksmanship Instructor and earned his Master Trainer Specialist qualification while helping Jocko rebuild and enhance these training programs into the highly effective platforms they are today. J.P. brings exceptional experience and frontline leadership perspective from the winning mindset and culture of Task Unit Bruiser.

Chantelle Doyle moves pollen between locations hoping to establish new plant populations and increase genetic diversity giving struggling species a boost.

In this episode of The Jordan Syatt Podcast, I speak with Elana Silber, The CEO of Sharsheret (@sharsheretofficial), a national non-profit organization that helps women and families living with breast and/or ovarian cancer.We discuss:- How Sharsheret fills the gaps in cancer support- Genetic testing and BRCA awareness- How you can get help from Sharsheret for free- How Sharsheret came to be- And more...I hope you enjoy this episode and, if you do, please leave a review on iTunes or Spotify (huge thank you to everyone who has written one so far).Finally, if you've been thinking about joining The Inner Circle but haven't yet... we have hundreds of home and bodyweight workouts for you and you can get them all here: https://www.sfinnercircle.com/

Send us a textOn the latest WTR Small-Cap Spotlight podcast episode, we welcomed Jan Eryk Umiastowski, CFO of GenSight Biologics (Euronext Paris: SIGHT), a late clinical-stage biopharma company based in Paris, France, primarily focused on developing and commercializing novel disease-modifying gene therapies aimed at reversing vision loss from severe neurodegenerative retinal diseases. He discusses GenSight's development pipeline, what's unique about  the company's approach to gene therapy and upcoming target milestones.

In this captivating episode of the Alberta Conservationist Podcast, join host Mark Hall as he delves into the fascinating world of genetics and wildlife conservation with Dr. Alfred Roca from the University of Illinois. Discover how Illinois' white-tailed deer population carries genetic variants that offer significant protection against chronic wasting disease (CWD). Explore the implications of these findings for wildlife management and the potential historical factors that have shaped these genetic defenses. Whether you're a wildlife enthusiast or a conservation professional, this episode offers valuable insights into the genetic battles being waged in nature. Tune in for a thought-provoking discussion that bridges science and conservation. Learn more about your ad choices. Visit megaphone.fm/adchoices

In this week's deep-dive, we're taking you into a case that haunted California for decades and still sends a chill through anyone who reads the details. For more than ten years, a masked predator moved through neighborhoods like a ghost — breaking into homes, stalking families, and leaving devastation behind. The numbers alone are staggering: over a hundred burglaries, at least fifty sexual assaults, and thirteen confirmed murders. He slipped between counties and police departments, stayed a step ahead of massive task forces, and then — somehow — disappeared. Not into the shadows, but into ordinary suburban life, where he lived free for more than forty years.This is the full story of Joseph James DeAngelo — the man the world would come to know as the Golden State Killer. We start back in 1974 in Visalia, a small agricultural city where a strange series of burglaries had detectives completely rattled. The person behind them wasn't grabbing TVs or cash. He was spending hours inside people's homes, taking small, personal things — a single earring, coins, women's underwear — and rearranging objects in ways that felt deliberate and unsettling. It wasn't just theft. It was a message: I was here. I know you. I can get to you.From there, we follow the escalation as the Visalia Ransacker's crimes tip into attempted abduction and then murder. We walk through the December 1975 killing of Claude Snelling, a journalism professor who died protecting his teenage daughter from being taken.And we cover the terrifying near-capture just two days later, when Detective William McGowen fought the prowler face-to-face and survived only because the suspect's gun misfired at point-blank range.Then the nightmare shifts north. In 1976, Sacramento is hit by a new kind of terror.The East Area Rapist begins attacking women in their homes with a level of planning and cruelty that left investigators stunned. We break down how his assaults evolved, including the moment he began targeting couples — tying up husbands and boyfriends, stacking dishes on their backs, and forcing them to listen helplessly while he raped their partners. We look at the psychological warfare he used to control entire communities: threatening phone calls, stalking routines, and the methodical surveillance he did before striking again.As the years pass, his crimes migrate south — and turn deadly. Starting in 1979, the man now known as the Original Night Stalker begins murdering couples in their homes across Santa Barbara, Ventura, and Orange counties. We go crime scene by crime scene, showing how the evidence slowly — and finally — revealed that Visalia, Sacramento, and Southern California were all connected to the same offender.We also dig into the long, frustrating decades of investigation: the dead ends, the jurisdictional chaos, and the breakthroughs that came only when DNA technology caught up to the case. And of course, we cover the seismic moment in 2018 when genetic genealogy identified the suspect, leading detectives straight to DeAngelo's quiet home in Citrus Heights — the same kind of suburb he once terrorized.The twist that still hits like a gut punch? During the height of his crime spree, DeAngelo was a police officer, using his training and insider knowledge to stay invisible.We close with the plea and sentencing — a historic reckoning where fifty-three victims and family members stood up in court to face the man who had stolen so much from them. Their impact statements are heartbreaking, powerful, and a reminder that this story isn't just about the monster — it's about the people who survived him. This episode is the result of hundreds of hours of research across court records, investigative files, victim testimony, and years of reporting. Our goal was to tell this story with care, accuracy, and respect — honoring the victims and the investigators who refused to let the case die. The Golden State Killer investigation didn't just end with an arrest. It changed law enforcement forever. Genetic genealogy opened a door to solving cold cases that once seemed impossible, and we talk about both the promise of that tool and the ethical questions that come with it.And we take a moment to recognize Michelle McNamara, whose relentless work on I'll Be Gone in the Dark helped reignite national attention and kept pressure on the investigation. She died in 2016, two years before DeAngelo was caught, but her voice and determination are woven into the story of how this case was finally solved. If you think you know this case, stick with us — because when you lay every chapter out in full, the scale and horror of what happened, and the way it was finally unraveled, is almost impossible to comprehend.

Hi friend — welcome back to The Habit Within! I'm Camille Kinzler, and today we're diving into a topic that quite literally changed the way I understand my body, my energy, and the way I move through midlife: genomics.If you've ever wondered why you're exhausted even when you're “doing everything right,” why weight feels harder to release than ever, or why your sleep has become unpredictable and shallow — this episode will blow your mind in the most empowering way.Because here's the truth:You're not broken.You're not undisciplined.And you're not imagining it.Your genes hold a living, breathing blueprint — one that shows us exactly what your body needs in this season of your life to feel energized, lighter, clearer, and more grounded.In this episode, I walk you through:The three things almost every midlife woman truly wants (and why your genes can help you get there)The major differences between ancestry tests like 23andMe and functional genomicsWhy your genes are not your destiny — and how epigenetics lets you turn certain expressions on or offHow your genetic profile influences:energy productionstubborn weightdetox bottlenecksinflammationcortisol patternssleep rhythmgut repairhormone pathwaysmicronutrient needsand even what kind of workouts your body thrives onWhat it looks like to walk through your results with a guide — instead of staring at a PDF wondering “now what?”How I've personally changed my own routines, nutrition, and daily rhythms since getting my results backThis is one of those episodes that leaves you thinking: Oh… that explains everything. Not in a doom-y way — in a deeply liberating way.Because when you understand your blueprint, you stop fighting your body.You start supporting it.I'd love to hear from youHave you ever taken a genetic test? Did it give you clarity — or just more questions?Come share with me, I love hearing how these conversations land for you.If you're tired of feeling exhausted, irritable, moody, and just not like yourself, schedule a free 30-minute consultation so I can help you feel like YOU again Fill out this brief form (2 min) to schedule a free 30-minute call. Love the show? Leave a 5-star review, and let me know what hit home for you. Find me on Instagram @camille_kinzler and leave me a DM!

Dr. Gregg Day and Professor Jonathan Rohrer discuss the significance of studying individuals at risk of developing genetic frontotemporal dementia, focusing on how early cognitive changes before symptoms appear can inform research and future therapeutic trials.  Show citation: Russell LL, Bouzigues A, Convery RS, et al. Executive Function Deficits in Genetic Frontotemporal Dementia: Results From the GENFI Study. Neurol Genet. 2025;11(4):e200248. Published 2025 Jul 21. doi:10.1212/NXG.0000000000200248 

Dr. Gregg Day talks with Professor Jonathan Rohrer about the significance of studying individuals at risk of developing genetic frontotemporal dementia, focusing on how early cognitive changes before symptoms appear can inform research and future therapeutic trials.  Read the related article in Neurology®Genetics. Disclosures can be found at Neurology.org.    

Episode SummaryIn this Worldview Wednesday episode, Joel Settecase tackles a classic question: “If we all came from Adam and Eve, who did their kids marry?” Drawing from Genesis 4 and 5, Joel explains that Cain married one of Adam and Eve's descendants—most likely a sister or niece—and why that fits perfectly within a biblical worldview.Key PointsEve was the mother of all living, so all humanity came from her line.Close-relative marriage wasn't prohibited until Leviticus 18.Early humans lived longer, allowing rapid population growth.Genetic decline after the Fall explains why such marriages later became harmful.The unity of the human race points to our shared need for redemption in Christ.Apologetic InsightThis isn't just about ancient genealogy—it's about biblical authority and human origins. The Genesis account holds together logically, scientifically, and theologically in ways secular explanations cannot.TakeawayCain's wife was a descendant of Adam and Eve, proving the Bible's consistency and humanity's shared story under one Creator and Redeemer.Calls to ActionPartner with The Think Institute at thethink.institute/partnerJoin the Hammer & Anvil Society at thethink.institute/societySubscribe and share Worldview Legacy to help more believers think biblically.

When Abby Fish, who was still under the age of 2 in the summer of 2025 was diagnosed with the Pediatric Brain Cancer Choroid Plexus Carcinoma, her mom Amelia and her dad Joel were told how rare and difficult this cancer was. When they then found out that Abby also had the genetic condition Li Fraumeni to go along with her Brain cancer, they were told that the chances of her surviving until she was at least 5 years old were less than 12 percent. After hearing that, they found the Burzynski Clinic in Houston Texas, and that Dr. Burzynski had treated a young woman named Kaityln who is now 25 years old, and had suffered from both the same cancer and same genetic condition that Abby has. Abby is now following the same treatment path that Kaitlyn did.

Muscular dystrophy (MD) is a group of genetic diseases that affect about 16 to 25 per 100,000 people in the US, with the most common childhood form being Duchenne muscular dystrophy (DMD) and the most common adult form being myotonic dystrophy. The prevalence of DMD is estimated at around 1 in 3,500 live male births. Prenatal carrier screening for this is part of the ACMG Tier 3 expanded carrier panel. This is different from spinal muscular atrophy (SMA). As we recently had a patient who was a MD carrier, with affected male children, who we cared for, we decided to do a quick review of muscular dystrophy: its prevalence, genetics, and evaluation of asymptomatic maternal carriers.1. https://www.mda.org/disease/duchenne-muscular-dystrophy/causes-inheritance2.https://www.nichd.nih.gov/health/topics/musculardys/conditioninfo/causes3. https://www.nhs.uk/conditions/muscular-dystrophy/4. ACMG: https://thednaexchange.com/2022/03/30/acmg-carrier-screening-guideline-the-hypothetical-tier-3-panel/#:~:text=The%20goal%20of%20this%20ACMG,1%20in%2040%2C000%20or%20higher.

Você já comeu Jambu? Pelo menos já ouviu falar? O açaí com certeza todos conhecem, mas será que você conhece o açaí de verdade? Como essas comidas se inserem na cultura e economia da região norte do Brasil? Como funciona cientificamente a famosa sensação de "adormecimento" do jambu? Patronato do SciCast: 1. Patreon SciCast 2. Apoia.se/Scicast 3. Nos ajude via Pix também, chave: contato@scicast.com.br ou acesse o QRcode: Sua pequena contribuição ajuda o Portal Deviante a continuar divulgando Ciência! Contatos: contato@scicast.com.br https://twitter.com/scicastpodcast https://www.facebook.com/scicastpodcast https://www.instagram.com/PortalDeviante/ Fale conosco! E não esqueça de deixar o seu comentário na postagem desse episódio! Expediente: Produção Geral: Tarik Fernandes e André Trapani Equipe de Gravação: Tarik Fernandes, Marcelo de Matos, Gustavo Rebello, Lenin Machado, Daniela Andrade, Diego Squinello Citação ABNT: Scicast #670: Sabores e Tradições Amazônicas: Açaí e Jambu. Locução: Tarik Fernandes, Marcelo de Matos, Gustavo Rebello, Lenin Machado, Daniela Andrade, Diego Squinello. [S.l.] Portal Deviante, 20/11/2025. Podcast. Disponível em: https://www.deviante.com.br/podcasts/scicast-670 Imagem de capa: Expotea: https://expotea.com.br/https://www.instagram.com/expoteabrasil/ Referências e Indicações EMBRAPA (Empresa Brasileira de Pesquisa Agropecuária). "Açaí: o fruto da Amazônia". Disponível em: https://www.embrapa.br/tema-acai SILVA, S. M. et al. "Características nutricionais e funcionais do açaí (Euterpe oleracea Mart.)". Revista Brasileira de Fruticultura, 2014. SEBRAE (Serviço Brasileiro de Apoio às Micro e Pequenas Empresas). "Cadeia produtiva do açaí no Brasil". Disponível em: https://www.sebrae.com.br/sites/PortalSebrae/ufs/pa/artigos/a-cadeia-produtiva-do-acai JUNQUEIRA, N. T. V.; ROCHA, F. S. "Botânica e fruticultura do açaí". Revista Brasileira de Fruticultura, 2016. CAVALCANTE, P. B. "Frutas comestíveis da Amazônia". Belém: Museu Paraense Emílio Goeldi, 2010. MUÑIZ-MIRET, N. et al. "Genetic diversity of Euterpe oleracea Mart. in the Amazon". Scientia Agricola, 1996. INSTITUTO SOCIOAMBIENTAL (ISA). "Povos e comunidades tradicionais da Amazônia". Disponível em: https://www.socioambiental.org Canal Rural: “Pará exporta mais de 61 mil toneladas de açaí por ano, aponta estudo” Disponível em: https://www.canalrural.com.br/agricultura/para-exporta-mais-de-61-mil-toneladas-de-acai-por-ano-aponta-estudo Agência Pará: “Dia do Açaí: Pará segue na liderança nacional com mais de 90% da produção brasileira” Disponível em: https://agenciapara.com.br/noticia/59374/dia-do-acai-para-segue-na-lideranca-nacional-com-mais-de-90-da-producao-brasileira Estado de Minas: “Açaí brasileiro vira febre fora do país e ganha o mundo” Disponível em: https://www.em.com.br/app/noticia/economia/2023/10/15/internas_economia%2C1576667/acai-brasileiro-vira-febre-fora-do-pais-e-ganha-o-mundo.shtml Acai Berry Market Set to Thrive at an Impressive 11.5% CAGR Disponível em: https://www.newstrail.com/acai-berry-market-set/ BARBOSA, A. P. et al. "Compostos bioativos do jambu: uma revisão". Revista Brasileira de Farmacognosia, 2016. SILVA, S. M. et al. "Propriedades medicinais e culinárias do jambu (Acmella oleracea)". Revista Brasileira de Plantas Medicinais, 2015. Sugestões de vídeos: A lenda da mandioca (recomendado para crianças): https://www.youtube.com/watch?v=zSBsJTSX3AE Sugestões de links: Sobre diferenciar mandioca brava e mansa: https://www.cpt.com.br/dicas-cursos-cpt/e-possivel-diferenciar-mandioca-brava-da-de-mesa https://www.embrapa.br/embrapa-no-cirio/jambu https://ainfo.cnptia.embrapa.br/digital/bitstream/item/56524/1/n12-etnocultivo-do-jambu-p.pdfSee omnystudio.com/listener for privacy information.

Drive with Dr. Peter Attia: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Antonio Bianco is a world-renowned physician-scientist and expert in thyroid physiology and metabolism. In this episode, Antonio explores the complex biology of thyroid hormone production, conversion, and regulation—highlighting how deiodinase enzymes modulate hormone activity at the tissue level and why that matters for interpreting lab results. He discusses the shortcomings of relying solely on TSH as a marker of thyroid function, the ongoing debate around combination therapy with T3 and T4 versus standard T4 treatment, and how genetics, tissue sensitivity, and individual variability influence thyroid hormone metabolism. The conversation also examines how hypothyroidism affects energy, mood, cognition, and longevity; why some patients remain symptomatic despite "normal" labs; and how future research could reshape treatment paradigms. We discuss: How the thyroid produces, stores, and activates hormones like T4 and T3 to finely regulate thyroid activity [2:45]; How fasting alters thyroid hormones to conserve energy [12:45]; Action of the deiodinases: how D1, D2, and D3 enzymes control the activation and inactivation of thyroid hormones [19:15]; The normal function of thyroid hormone and the roles of the hypothalamus, pituitary gland, and deiodinases in maintaining hormonal balance [23:30]; Why understanding thyroid physiology is essential for proper diagnosis and treatment of hypothyroidism [33:45]; Testing for thyroid hormones: understanding free vs. total levels, the limitations of current T3 assays, best practices, and more [36:00]; Genetic and sex-based variability in thyroid hormone regulation and their limited clinical significance [43:45]; Hyperthyroidism: causes, symptoms, diagnosis, and treatment options [46:00]; Hypothyroidism: diagnosis and autoimmune causes of hypothyroidism [56:30]; More on hypothyroidism: diagnostic biomarkers, antibody patterns, and non-autoimmune presentations [1:05:00]; Thyroid hormone replacement therapy [1:15:15]; More on thyroid replacement strategies: exploring the evidence gaps, mortality signals, effects on lipids, and more [1:28:00]; Hypothyroidism basics: causes, antibody implications (including pregnancy), and how to make the diagnosis before choosing therapy [1:35:15]; Thyroid medication: compounded controlled-release T3, brand name versus generic, and what Antonio prescribes to newly diagnosed hypothyroid patients [1:42:45]; Redefining treatment success: why normalizing TSH isn't always enough for patients with hypothyroidism [1:54:45]; Case studies: analysis of two unusual cases of thyroid disease [1:57:00]; Dangers of supplementing with high levels of iodine, and female-specific risk of thyroid disease [2:05:45]; Case study of a patient who presents with elevated TSH but no symptoms [2:09:30]; How future research could reshape treatment, and Antonio's new book called "Rethinking Hypothyroidism" [2:13:15]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

A study found that alcohol raises dementia risk at every level of drinking, overturning decades of claims that moderate use protects your brain Even light drinking damages neurons, disrupts mitochondrial energy production, and accelerates brain aging, showing there is no safe dose for cognitive health Genetic data revealed that for every measurable increase in alcohol consumption, dementia risk rose by about 15%, with the danger extending across all age and ancestry groups Alcohol and linoleic acid (LA) from seed oils follow the same toxic pathway in your liver, creating harmful aldehydes that cause mitochondrial damage and fatty liver disease, both of which impair brain function Reducing or eliminating alcohol and cutting seed oils to under 5 grams per day — ideally 2 grams — support liver recovery, restore mitochondrial function, and protect long-term brain health

Dr. Haroldo Magarinos is a Chilean dentist specializing in Periodontics, Oral Medicine, and Implantology. After over a decade of conventional practice and university teaching, he decided to pursue his passion and become a board-certified naturopathic doctor in 2018. He also specialized in Integrative Biological Dental Medicine, Homeopathy, Live blood analysis, Peptide therapy, and Advanced Clinical Ozone therapy. Dr. Haroldo has long been a strong advocate for studying the human microbiome, firmly believing that treating patients with dysbiosis can prevent and even reverse many prevalent forms of chronic disease. He currently works as a clinical consultant in microbiome metagenomic analysis for Microbiome Labs and is the co-founder and director of Revolution Gut Health, an online platform that offers coaching services to everyone who wants to learn and improve microbiome-related health conditions. In this episode, Dr. Haroldo Magarinos explains how detoxification works in the body and a gives detailed overview of his detoxification supplements.    RESOURCES: Learn more about Dr. Magarinos here: www.detoxu.com Instagram: @drharoldo Previous podcast episodes with Dr. Magarinos: https://www.taragarrison.com/blog/drharoldomagarinos2 and https://www.taragarrison.com/blog/drharoldomagarinos  Get 15% off Peluva minimalist shoe with coupon code COACHTARA here: http://peluva.com/coachtara   CHAPTERS:   CHAPTERS: 0:00 Intro 4:20 Is detox real? 7:00 Environmental challenges 9:40 Genetic and other factors 12:15 Some tell tale signs of compromised detox pathways 15:20 An overview of detoxification 20:55 3 main areas of detoxification 24:30 Bioaccumulation of toxins 25:58 Dr Magarinos' detox supplements 51:00 How to locate those products   WORK WITH ME: Are You Looking for Help on Your Wellness Journey? Here's how I can help you: TRY COACH TARA APP FOR FREE: http://taragarrison.com/app LEVEL UP PROGRAM: http://taragarrison.com/level-up INDIVIDUAL ONLINE COACHING: https://www.taragarrison.com/work-with-me CHECK OUT HIGHER RETREATS: https://www.taragarrison.com/retreats   SOCIAL MEDIA:  Instagram @coachtaragarrison TikTok @coachtaragarrison Facebook @coachtaragarrison Pinterest @coachtaragarrison   INSIDE OUT HEALTH PODCAST SPECIAL OFFERS: ☑️ Upgraded Formulas Hair Test Kit Special Offer: https://bit.ly/3YdMn4Z ☑️ Upgraded Formulas - Get 15% OFF Everything with Coupon Code INSIDEOUT15: https://upgradedformulas.com/INSIDEOUT15 ☑️ Rep Provisions: Vote for the future of food with your dollar! And enjoy a 15% discount while you're at it with Coupon Code COACHTARA: https://bit.ly/3dD4ZSv   If you loved this episode, please leave a review! Here's how to do it on Apple Podcasts: Go to Inside Out Health Podcast page: https://podcasts.apple.com/us/podcast/inside-out-health-with-coach-tara-garrison/id1468368093 Scroll down to the 'Ratings & Reviews' section. Tap 'Write a Review' (you may be prompted to log in with your Apple ID). Thank you!

In this episode of the Gladden Longevity Podcast, Dr. Jeffrey Gladden and Trevor Connor delve into the intricacies of nutrition, particularly focusing on the Paleo diet, its principles, and its implications for health and longevity. Trevor shares his personal journey from professional cycling to studying nutrition, highlighting the importance of nutrient density and the role of glycemic load in dietary choices. They discuss the significance of the glycocalyx in vascular health, the impact of antioxidants on exercise adaptations, and the interplay between genetics and endurance training. The conversation emphasizes the necessity of balancing diet and exercise for optimal health. In this conversation, Dr. Jeffrey Gladden and Trevor Connor explore the intricate relationship between diet, exercise, and longevity, particularly focusing on the Paleo diet. They discuss common misconceptions about the diet, the importance of balance and variety in nutrition, and the role of metabolic pathways like AMPK and P53 in health. The conversation emphasizes the significance of genetic testing to tailor dietary choices and the need for a balanced approach to fueling during exercise. They conclude with resources for further learning about the Paleo diet and its benefits for health and longevity.    For Audience        Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/ !    Takeaways         Trevor Connor transitioned from professional cycling to studying nutrition.         The Paleo diet emphasizes foods our ancestors evolved with.         Nutrient density is more important than macronutrient ratios.         Glycemic load is a key factor in dietary health.         The glycocalyx plays a crucial role in vascular health.         Antioxidants can hinder training adaptations if taken pre-exercise.         Genetics influence how individuals respond to endurance training.         Strength training may enhance antioxidant defenses more than endurance training.         A balanced approach to diet and exercise is essential for health.         You cannot out supplement a poor diet.  You can't run your way out of a bad diet.         A balanced approach to diet is crucial.         Biology operates on the principle of balance.         Variety in diet is essential for health.         Understanding metabolic pathways is key to longevity.         Genetic testing can guide dietary choices.         Fueling during exercise should be based on individual needs.         The sports nutrition world may promote unhealthy practices.         Natural foods are better for health than processed sugars.         Focus on overall health rather than just performance.   Chapters 00:00 Introduction to Longevity and Nutrition 02:59 Trevor's Journey into Paleo Diet 05:52 Understanding the Paleo Diet 09:02 Nutrient Density and Glycemic Load 12:01 The Role of Glycocalyx in Vascular Health 14:59 Antioxidants and Exercise Adaptations 17:57 Genetics and Endurance Training 20:51 Balancing Diet and Exercise for Optimal Health 23:12 The Balance of Diet and Exercise 24:51 Misconceptions of the Paleo Diet 27:38 Metabolic Flexibility and Variety in Diet 29:38 Understanding AMPK and P53 Pathways 32:23 The Importance of Genetic Testing 36:50 Fueling During Exercise: Myths and Realities To learn more about Trevor Connor/Paleo Diet:Facebook: https://www.facebook.com/RealPaleoDiet/ Instagram: https://www.instagram.com/realpaleodiet/ Email: info@thepaleodiet.com Website: thepaleodiet.com   Got a question for Dr. Gladden? Submit it using the link below and it might be answered in our next Q&A episode! https://form.typeform.com/to/tIyzUai7? Reach out to us at:    Website: https://gladdenlongevity.com/     Facebook: https://www.facebook.com/Gladdenlongevity/    Instagram: https://www.instagram.com/gladdenlongevity/?hl=en     LinkedIn: https://www.linkedin.com/company/gladdenlongevity    YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw     Gladden Longevity Podcast Disclosures Production & Independence The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas. Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements. Medical Disclaimer The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content. The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options. Use of information from this podcast and any linked materials is at the listener's own risk. Podcast Guest Disclosures Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team. Sponsorships & Affiliate Disclosures To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes. We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented. Additional Note on Content Integrity All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.  

In 2016, Ludovic Orlando, a genetics researcher, embarked on the Pegasus Project, an ambitious endeavor to use genetics to discover the origin of the modern horse. There were plenty of theories as to who domesticated horses first–but Ludovic's team came up with their answer: They emerged on the western Eurasian steppe around 4200 years ago. But that revelation was only the beginning of Ludovic's work, as he dug into the genetic origins of different kinds of horses, like the Arabian horse, as well as charted how the horse's genetic diversity changed over time. His research is collected in his new book Horses: A 4,000-Year Genetic Journey Across the World (Princeton UP, 2025) Ludovic Orlando is a CNRS Silver Medal–winning research director and founding director of the Centre for Anthropobiology and Genomics of Toulouse at the University of Toulouse in France. His work has appeared in leading publications such as Nature, Science, and Cell. He is a recipient of the American Association for the Advancement of Science's Newcomb Cleveland Prize. You can find more reviews, excerpts, interviews, and essays at The Asian Review of Books, including its review of Horses. Follow on Twitter at @BookReviewsAsia. Nicholas Gordon is an editor for a global magazine, and a reviewer for the Asian Review of Books. He can be found on Twitter at@nickrigordon. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Antonio Bianco is a world-renowned physician-scientist and expert in thyroid physiology and metabolism. In this episode, Antonio explores the complex biology of thyroid hormone production, conversion, and regulation—highlighting how deiodinase enzymes modulate hormone activity at the tissue level and why that matters for interpreting lab results. He discusses the shortcomings of relying solely on TSH as a marker of thyroid function, the ongoing debate around combination therapy with T3 and T4 versus standard T4 treatment, and how genetics, tissue sensitivity, and individual variability influence thyroid hormone metabolism. The conversation also examines how hypothyroidism affects energy, mood, cognition, and longevity; why some patients remain symptomatic despite "normal" labs; and how future research could reshape treatment paradigms. We discuss: How the thyroid produces, stores, and activates hormones like T4 and T3 to finely regulate thyroid activity [2:45]; How fasting alters thyroid hormones to conserve energy [12:45]; Action of the deiodinases: how D1, D2, and D3 enzymes control the activation and inactivation of thyroid hormones [19:15]; The normal function of thyroid hormone and the roles of the hypothalamus, pituitary gland, and deiodinases in maintaining hormonal balance [23:30]; Why understanding thyroid physiology is essential for proper diagnosis and treatment of hypothyroidism [33:45]; Testing for thyroid hormones: understanding free vs. total levels, the limitations of current T3 assays, best practices, and more [36:00]; Genetic and sex-based variability in thyroid hormone regulation and their limited clinical significance [43:45]; Hyperthyroidism: causes, symptoms, diagnosis, and treatment options [46:00]; Hypothyroidism: diagnosis and autoimmune causes of hypothyroidism [56:30]; More on hypothyroidism: diagnostic biomarkers, antibody patterns, and non-autoimmune presentations [1:05:00]; Thyroid hormone replacement therapy [1:15:15]; More on thyroid replacement strategies: exploring the evidence gaps, mortality signals, effects on lipids, and more [1:28:00]; Hypothyroidism basics: causes, antibody implications (including pregnancy), and how to make the diagnosis before choosing therapy [1:35:15]; Thyroid medication: compounded controlled-release T3, brand name versus generic, and what Antonio prescribes to newly diagnosed hypothyroid patients [1:42:45]; Redefining treatment success: why normalizing TSH isn't always enough for patients with hypothyroidism [1:54:45]; Case studies: analysis of two unusual cases of thyroid disease [1:57:00]; Dangers of supplementing with high levels of iodine, and female-specific risk of thyroid disease [2:05:45]; Case study of a patient who presents with elevated TSH but no symptoms [2:09:30]; How future research could reshape treatment, and Antonio's new book called "Rethinking Hypothyroidism" [2:13:15]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

Welcome back to Beautifully Broken, where healing meets high performance. Today, I'm joined by the luminous Dr. Shivani Gupta, founder of Fusionary Formulas and author of The Inflammation Code. Shivani's story begins with a home full of mold, hair loss, and a reminder that even the healthiest among us can get blindsided by hidden toxins. What followed was a journey of deep functional medicine testing, emotional regulation, and fierce self-advocacy—proof that healing is never linear.We talk about the real root of “inflamma-aging,” why brain fog and fatigue are not normal, and how inflammation is at the center of most chronic disease. Shivani breaks down the six Ayurvedic pillars of anti-inflammatory living, the importance of circadian alignment (especially the 10–2 window), and why tea time is more than self-care—it's medicine.From tongue scraping and turmeric to sleep hygiene and self-awareness, this episode is full of accessible practices that bring ancient rituals into modern life. Whether you're battling burnout, navigating hormonal chaos, or simply ready to feel more alive, Shivani's wisdom will help you rewrite your own inflammation code. Episode Highlights[00:00] – Living with mold: the surprise diagnosis that changed everything[03:30] – Mold dogs, remediation, and the truth about “healthy homes”[06:40] – Why no supplement can fix a toxic environment[09:10] – Genetic resilience, functional testing, and understanding bio-individuality[13:05] – Hair loss as a metabolic signal and the timeline of toxic exposure[17:00] – Fear, mindset, and emotional regulation during mold recovery[18:52] – The Inflammation Code: aging, Ayurveda, and winning at inflammation[22:45] – Cycles, seasons, and building your Ayurvedic circadian rhythm[26:19] – Mental inflammation: the hidden driver of burnout and disease[30:40] – Building an anti-inflammatory lifestyle from the ground up[36:57] – Why doctors stay in their lanes—and why you must self-advocate[39:22] – Pitta, Kapha, and using fire time for healing and repair[45:24] – Ayurvedic sleep rituals and the power of forgiveness in wellness[47:21] – Tea time is me time: micro-moments of self-care that change your biology[53:37] – The 12 daily rituals for detox, digestion, and emotional balance[55:15] – Tongue scraping, turmeric, and the simple tools that actually work[58:56] – How to cycle supplements, build awareness, and measure results[1:01:26] – The spreadsheet of supplements: data meets intuition[1:03:02] – Big love, big lessons, and the path to sustainable healingConnect With Dr. ShivaniDr. Shivani Gupta: https://drshivani.comThe Inflammation Code (Preorder): https://theinflammationcode.comGet Your UpgradeVisionary Formulas: https://fusionaryformulas.com/?sca_ref=9671297.FAK6ESUdt3R9--- Code: BEAUTIFULLYBROKENThe Biological Blueprint Program: https://www.beautifullybroken.world/Beam Minerals: http://beamminerals.com/beautifullybroken— Code: BEAUTIFULLYBROKENSilver Biotics: bit.ly/3JnxyDD— 30% off with Code: BEAUTIFULLYBROKENLightPathLED: https://lightpathled.pxf.io/c/3438432/2059835/25794— Code: beautifullybrokenCatchBio: https://www.catchbio.com/beautifullybroken — Code: BEAUTIFULLYBROKEN   CONNECT WITH FREDDIEWork with Me: https://www.beautifullybroken.world/biological-blueprintWebsite and Store: (http://www.beautifullybroken.world) Instagram: (https://www.instagram.com/beautifullybroken.world/) YouTube: https://www.youtube.com/@freddiekimmel Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Nearly 7 million Americans currently live with Alzheimer’s and by 2060, experts say that number could be as high as 14 million. Scientists are trying to find out how one man has been able to stave off Alzheimer's for 25 years, despite having a rare genetic mutation that, doctors say, essentially guaranteed he’d develop the disease. Pam Belluck of The New York Times joins Ali Rogin to discuss. PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy

Migration Routes and Genetic Groups 2. Professor Meltzer details the migration routes of ancestral Native Americans, explaining that while they crossed the land bridge during maximum glaciation, they were initially trapped in Alaska by two vast continental ice sheets. The "ice free corridor" along the Rockies was not a viable route until around 13,000 years ago, so the likely path was down the Pacific coast, which may have cleared as early as 16,500 years ago. Meltzer introduces the concept of a "genetic ghost," which is evidence in the genomic record of a contributing population for which no physical sample has yet been found.