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Topics: (00:00:00) - Intro(00:03:26) - Marathon misadventures(00:06:15) - The failed acquisition(00:13:47) - Lessons from the deal(00:29:31) - The future of retail(00:33:44) - Empathy for founders(00:35:23) - The grind of capitalism(00:35:37) - Challenges for young founders(00:36:10) - The importance of peer support(00:37:17) - Scaling and growth pains(00:37:42) - Exciting new ventures(00:38:20) - Genetic engineering innovations(00:43:40) - Revolutionizing air freight with airships(00:49:56) - Terraform Industries: Energy independence(01:02:17) - Innovative warehouse automation(01:05:25) - Mining industry disruption(01:09:45) - Conclusion and future outlook Links: Join us in Rolling Fun! Hear our other Rolling Fun eps! To support the costs of producing this podcast: >> Buy a copy of the Navalmanack: www.navalmanack.com/ >> Buy a copy of The Anthology of Balaji: https://balajianthology.com/ >> Sign up for my online course and community about building your Personal Leverage: https://www.ejorgenson.com/leverage >> Invest in early-stage companies alongside Eric and his partners at Rolling Fun: https://angel.co/v/back/rolling-fun >> Join the free weekly email list at ejorgenson.com/newsletter >> Text the podcast to a friend >> Or at least give the podcast a positive review to help us reach new listeners! We discuss: Why personal networks matter most when raising money quickly for big deals New investments in companies building genetically engineered animals, advanced airships, and solar-powered synthetic natural gas How real operational experience shapes the way we invest and support founders The balance of optimism and realism required to keep taking shots in business Quotes from Al: “Just keep taking the shots. A shooter's gotta shoot.” “Sometimes you take the shot, do everything right, and the ball still doesn't go in.” “There's no classy way to advertise, ‘Hey, your favorite store died—but we're a good rebound.'” “Capitalism is an unforgiving mistress.” “Personal relationships were the most valuable asset I had in that deal.” “Sometimes I think, ‘I should be inventing Facebook 2,' but here I am—investing in fabric.” “I've never worked on a deal that hard. It should have gone my way… and didn't.” “You wake up the next morning and it didn't happen, but I still have a great family, and my business is still running.” “It's hard until it isn't—and even when it isn't, it's still freaking hard.” Quotes from Bo: “We're actual operators—curious about what's possible with technology—and that makes us better investors.” “On a Thursday, ‘This deal is happening.' Then Tuesday? ‘It's over. We lost.'” “We have a unique amount of empathy for founders—because we know how hard this shit is.” “If you can pull it off, it's transformational. And that's awesome.” (on Airship) “A blimp is not a quadcopter to carry Al's big ass—it's an elegant, slow-moving blimp.” “There's a lot of industries still doing 90/10 in-store sales. That blew my mind.” “It's a real ‘software is eating the world' moment—but finally arriving at the mining industry.” “When you're building something that matters, you're playing the long game—even if the outcome is uncertain.” “The people who make glow-in-the-dark fish… now they're building unicorns. And yeah, it's gonna happen.”
In this conversation, Dr. Nick Wilson and Leah Wilson, J.D. explore the misconceptions surrounding genetic determinism and the impact of environmental factors on health. They discuss the nocebo effect, the influence of family health patterns, and the role of epigenetics in determining health outcomes. The conversation emphasizes the importance of nutrition and lifestyle choices in shaping genetic expression and encourages listeners to take control of their health narratives. In this thought-provoking episode, Dr. Nick and Leah Wilson explore the complex and often misunderstood topic of birth control. With honesty and compassion, they break down common misconceptions surrounding hormonal contraceptives: how they work, what they do to a woman's body, and the long-term impact they can have on health, fertility, and even relationships. Topics Covered: The nocebo effect can cause real harm to health. Family habits, not just genes, influence disease. Epigenetics shows that environment affects gene expression. Nutrition can turn genes on and off. You can change your health in as little as 90 days. Your body is constantly renewing itself. You are not a victim of your genes. Empowerment comes from understanding your health.
Some conditions hide in your genes, without any symptoms. One of these conditions is genetic arrhythmogenic cardiomyopathy, an inherited condition that can lead to sudden cardiac arrest — even if you feel completely fine.In this episode, Sarah and Leslie talk about their shared diagnosis of FLNC cardiomyopathy — from how this gene mutation affects the function of the heart to how they're managing this rare condition. You'll hear how Leslie's ICD has saved her life more than once, how it feels to be shocked back to life, and the resilience that's helped them move forward.This is a raw, real, emotional episode about living with a genetic heart condition. Tune in to learn the signs to watch for, when to get tested, and where to find support!Topics discussed in this episode:What is genetic arrhythmogenic cardiomyopathy?How FLNC-AC differs from other cardiomyopathiesCommon symptoms and some people are diagnosed too lateTreatment and lifestyle managementHow Sarah and Leslie finally got diagnosedLeslie's first cardiac arrest and its impactHow Sarah is processing her diagnosisWhat it feels like to be shocked by your ICDTypes of ICDs: transvenous, SICD, and EV-ICDMental and emotional recovery post-cardiac arrestThe WomenHeart organizationFind support or volunteer with WomenHeart:https://www.womenheart.org/Mentioned in this episode:Voices in NursingCheck out the Voices in Nursing Podcast here: https://www.aacn.org/education/podcast-series/voices-in-nursingCONNECT
Sponsored By: → Cornbread Hemp | For an exclusive offer go to cornbreadhemp.com/drg and use promo code DRG for 30% OFF your first order! Sign up for our newsletter! https://drchristiangonzalez.com/newsletter/ Cancer has been growing in your body for 8-10 years before you feel anything. While conventional doctors wait for symptoms—lumps, pain, bleeding—you're losing nearly a decade of prevention time. Dr. Leigh Erin Connealy, who runs one of America's largest integrative cancer centers, reveals the shocking truth: less than 1% of cancers are actually genetic. The rest are completely preventable, but medical school teaches disease management, not prevention protocols. She's developed blood tests that catch cancer before it becomes cancer, discovered why your emotions literally create disease in your body, and uses protocols to reverse what conventional medicine calls "incurable." Cancer rates are exploding in young people—this isn't wellness talk, it's life-or-death information that could save you or someone you love. In this episode, you'll learn: • Cancer's hidden 8-10 year timeline: from first abnormal cell to detectable tumor—why early intervention during this window can prevent cancer entirely, not just treat it after diagnosis • The real cancer causes: less than 1% genetic, 99% environmental factors including chronic stress, toxin exposure, and unresolved emotional trauma that keeps you in survival mode • Liquid biopsy breakthroughs: blood tests detecting circulating tumor cells years before imaging shows anything—90% accuracy in identifying cancer development before symptoms appear • Why conventional treatment fails: surgery, chemo, and radiation treat symptoms but ignore the toxic terrain that allowed cancer to develop in the first place • The emotional cancer connection: how chronic unresolved stress suppresses immune function and creates the acidic environment cancer thrives in—plus the device that identifies emotional conflicts in minutes • Advanced prevention protocols: comprehensive blood work detecting hormonal imbalances, heavy metals, and inflammatory markers that predict cancer risk years in advance • Low-dose chemotherapy revolution: using 10% conventional doses with insulin targeting and immediate detox support to maximize effectiveness while minimizing damage • The fungal theory of cancer: why medications like fenbendazole and ivermectin show anti-cancer properties and how to use them safely with proper liver protection • Personalized nutrition strategies: why there's no one-size-fits-all cancer diet and how to determine whether keto, plant-based, or other approaches work for your specific situation • Energy medicine integration: how frequency therapy, red light treatment, and cellular voltage optimization support healing at the deepest level alongside conventional treatments Timestamps: 0:00 - Introduction 2:31 - How Early Can Cancer Be Detected? 7:25 - The Biggest Truth About Cancer: 100% Preventable, Not Genetic 12:01 - Hormones & The Great Poisoning: Environmental Toxins Impact 17:45 - What Conventional Cancer Treatment Is Missing 27:08 - Integrative Cancer Protocols 32:04 - The Role of Emotions in Cancer 40:02 - Creating Healing Environments 45:17 - Repurposed Drugs: Fenbendazole, Ivermectin & Cancer Treatment 49:05 - Best Diets for Cancer 56:33 - Liquid Biopsies: Early Detection Technology & Prevention Focus
(00:00-14:00) Who do you like more, Harry Connick Jr or Gabe's new snack? Happy birthday to Jeff Burkett! Jackson liking guys with facial hair is a jealousy thing. A visually appalling genetic mistake. Does Wally's have house shoes? Following through on the Nolan Arenado audio tease. Nolan Arenado interviewed in Springfield ahead of a rehab start as he reflects on the year. Beards. Give me buzz cut Pitt.(14:08-27:37) Happy 48th Birthday to Ludacris. Don't get Jackson started on Crash. The Border War will be put on hold after next year's rematch in Lawrence. Audio of Lance Leipold talking about needing to play the border war “as often as they can.” Should we do a remote from Provo? A nasally cuckold.(27:47-52:41) So What'd Your Grandma Think featuring Dan Campbell of the Detroit Lions. People are wondering. Bonnie Raitt. Mt. Rushmore of Julia Roberts films. Late 80's loving. Biff is on the line and he's got the top chicken joints in St. Louis. Chicken wings with girls in the background without clothes on. Isn't it nice to get a double Mount Rushmore? How small are Ky's hands? Jackson putting together a Dream Team for the Lemmings Open.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Defenders: Doctrine of Man (Part 17): Genetic Challenges to Adam and Eve
Ataxia is a neurologic symptom that refers to incoordination of voluntary movement, typically causing gait dysfunction and imbalance. Genetic testing and counseling can be used to identify the type of ataxia and to assess the risk for unaffected family members. In this episode, Katie Grouse, MD, FAAN, speaks with Theresa A. Zesiewicz, MD, FAAN, author of the article “Ataxia” in the Continuum® August 2025 Movement Disorders issue. Dr. Grouse is a Continuum® Audio interviewer and a clinical assistant professor at the University of California San Francisco in San Francisco, California. Dr. Zesiewicz is a professor of neurology and director at the University of South Florida Ataxia Research Center, and the medical director at the University of South Florida Movement Disorders Neuromodulation Center at the University of South Florida and at the James A. Haley Veteran's Hospital in Tampa, Florida. Additional Resources Read the article: Ataxia Subscribe to Continuum®: shop.lww.com/Continuum Earn CME (available only to AAN members): continpub.com/AudioCME Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the American Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Full episode transcript available here Dr Jones: This is Dr Lyell Jones, Editor-in-Chief of Continuum. Thank you for listening to Continuum Audio. Be sure to visit the links in the episode notes for information about earning CME, subscribing to the journal, and exclusive access to interviews not featured on the podcast. Dr Grouse: This is Dr Katie Grouse. Today I'm interviewing Dr Theresa Zesiewicz about her article on ataxia, which appears in the August 2025 Continuum issue on movement disorders. Welcome to the podcast, and please introduce yourself to our audience. Dr Zesiewicz: Well, thank you, Dr Grouse. I'm Dr Theresa Zesiewicz, otherwise known as Dr Z, and I'm happy to be here. Dr Grouse: I have to say, I really enjoyed reading your article. It was a really great refresher for myself as a general neurologist on the topic of ataxia and a really great reminder on a great framework to approach diagnosis and management. But I wanted to start off by asking what you feel is the key message that you hope our listeners will take away from reading your article. Dr Zesiewicz: Yes, so, thanks. I think one of the key messages is that there has been an explosion and renaissance of genetic testing in the past 10 years that has really revolutionized the field of ataxia and has made diagnosis easier for us, more manageable, and hopefully will lead to treatments in the future. So, I think that's a major step forward for our field in terms of genetic techniques over the last 10 years, and even over the last 30 years. There's just been so many diseases that have been identified genetically. So, I think that's a really important take-home message. The other take-home message is that the first drug to treat Friedreich's ataxia, called omaveloxolone, came about about two years ago. This was also a really landmark discovery. As you know, a lot of these ataxias are very difficult to treat. Dr Grouse: Now pivoting back to thinking about the approach to diagnosis of ataxia, how does the timeline of the onset of ataxia symptoms inform your approach? Dr Zesiewicz: The timeline is important because ataxia can be acute, subacute or chronic in nature. And the timeline is important because, if it's acute, it may mean that the ataxia took place over seconds to hours. This may mean a toxic problem or a hypoxic problem. Whereas a chronic ataxia can occur over many years, and that can inform more of a neurodegenerative or more of a genetic etiology. So, taking a very detailed history on the patient is very important. Sometimes I ask them, what is the last time you remember that you walked normal? And that can be a wedding, that can be a graduation. Just some timeline, some point, that the patient actually walked correctly before they remember having to hold onto a railing or taking extra steps to make sure that they didn't fall down, that they didn't have imbalance. That sometimes that's a good way to ask the patient when is the last time they had a problem. And they can help you to try to figure out how long these symptoms have been going on. Dr Grouse: I really appreciate that advice. I will say that I agree, it can sometimes be really hard to get patients to really think back to when they really started to notice something was different. So, I like the idea of referencing back to a big event that may be more memorable to them. Now, given that framework of, you know, thinking through the timeline, could you walk us through your approach to the evaluation of a patient who presents to your clinic with that balance difficulties once you've established that? Dr Zesiewicz: Sure. So, the first thing is to determine whether the patient truly has ataxia. So, do they have imbalance? Do they have a wide base gait? That's very important because patients come in frequently to your clinic and they'll have balance problems, but they can have knee issues or hip issues, neuropathy, something like that. And sometimes what we say to the residents and the students is, usually ataxia or cerebellar symptoms go together with other problems, like ocular problems are really common in cerebellar syndromes. Or dysmetria, pass pointing, speech disorder like dysarthria. So, not only do you need to look at the gait, but you should look at the other symptoms surrounding the gait to see if you think that the patient actually has a cerebellar syndrome. Or do they have something like a vestibular ataxia which would have more vertigo? Or do they have a sensory ataxia, which would occur if a person closes his eyes or has more ataxia when he or she is in the dark? So, you have to think about what you're looking at is the cerebellar syndrome. And then once we look to see if the patient truly has a cerebellar syndrome, then we look at the age, we look at---as you said before, the timeline. Is this acute, subacute, or chronic? And usually I think of ataxia as falling into three categories. It's either acquired, it's either hereditary, or it's neurodegenerative. It can be hereditary. And if it's not hereditary, is it acquired, or is it something like a multiple system atrophy or a parkinsonism or something like that? So, we try to put that together and start to narrow down on the diagnosis, thinking about those parameters. Dr Grouse: That's really a helpful way to think through it. And it is true, it can get very complex when patients come in with balance difficulties. There's so many things you need to think about, but that is a great way to think about it. Of course, we know that most people who come in to the Movements Disorders clinic are getting MRI scans of their brains. But I'm curious, in which cases of patients with cerebellar ataxia do you find the MRI to be particularly helpful in the diagnosis? Dr Zesiewicz: So, an MRI can be very important. Not always, but- so, something like multiple system atrophy type C where you may see a hot cross bun sign or a pontine hyperintensity on the T2-weighted image, that would be helpful. But of course, that doesn't make the diagnosis. It's something that may help you with the diagnosis. In FXTAS, which is fragile X tremor/ataxia syndrome, the patient may have the middle cerebellar peduncle sign or the symmetric hyperintensity in the middle cerebellar peduncles, which is often visible but not always. Something like Wernicke's, where you see an abnormality of the mammillary bodies. Wilson's disease, which is quite rare, T2-weighted image may show hyperintensities in the putamen in something like Wilson's disease. Those are the main MRI abnormalities, I think, with ataxia. And then we look at the cerebellum itself. I mean, that seems self-evident, but if you look at a sagittal section of the MRI and you see just a really significant atrophy of the cerebellum, that's going to help you determine whether you really have a cerebellar syndrome. Dr Grouse: That's really encouraging to hear a good message for all of us who sometimes feel like maybe we're missing something. It's good to know that information can always come up down the line to make things more clear. Your article does a great review of spinal cerebellar ataxia, but I found it interesting learning about the more recently described syndrome of SCA 27B. Would you mind telling us more about that and other really common forms of SCA that's good to keep in mind? Dr Zesiewicz: Sure. So, there are now 49 types of spinal cerebellar ataxia that have been identified. The most common are the polyglutamine repeat diseases: so, spinocerebellar ataxia type 3 or type 2, type 6, are probably the most common. One of the most recent spinocerebellar ataxias to be genetically identified and clinically identified is spinocerebellar ataxia 27B. This is caused by a GAA expansion repeat in the first intron of the fibroblast growth factor on chromosome 13. And the symptoms do include ataxia, eye problems, downbeat nystagmus, other nystagmus, vertical, and diplopia. It appears to be a more common form of adult-onset ataxia, and probably more common than was originally thought. It may account for a substantial number of ataxias, like, a substantial percentage of ataxias that we didn't know about. So, this was really a amazing discovery on SCA 27B. Dr Grouse: Now a lot of us I think feel a little anxious when we think about genetic testing for ataxia simply because there's so many forms, things are changing quickly. Do you have a rule of thumb or a kind of a framework that we can think of as we approach how we should be thinking about getting genetic testing for the subset of patients? Dr Zesiewicz: Sure. And I think that this is where age comes into play a lot. So, if you have a child who's 10, 11, or 12 who's having balance problems in the schoolyard, does not have a history of ataxia in the family, the teachers are telling you that the child is not running correctly, they're having problems with physical education, that is someone who you would think about testing for Friedreich's ataxia. A preteen or a child, that would be one thing that would be important to test. When you talk to your patient, it's important to really take a detailed family history. Not just mom or dad, but ethnicity, grandparents, etc. And sometimes, once in a while, you come up with a known spinal cerebellar ataxia. Then you can just test for that. So, if a person is from Portugal or has Portugal background and they have ataxia and the parents had ataxia, you would think of spinal cerebellar ataxia type 3. Or if they're Brazilian, or if the person is from a certain area of Cuba and mom and dad had ataxia and that person has ataxia, you would think of spinal cerebellar ataxia type 2. Or if a person has ataxia and their parent had blindness or visual problems, you may be more likely to think of spinal cerebellar ataxia type 7, for example. If they have that---either they have a known genetic cause in in the family, first degree family, or they come from an area of the world in which we can pinpoint what type we think it is---you can go ahead and get those tests. If not, you can take an ataxia comprehensive panel. Many times now, if you take the panel and the panel is negative, it will reflex to the whole exome gene sequencing, where we're finding really unusual and more rare types of ataxia, which are very interesting. Spinal cerebellar ataxia type 32, spinal cerebellar ataxia type 36, I had a spinal cerebellar ataxia type 15. So, I think you should start with the age, then the family history, then where the person is from. And then, if none of those work out, you can get a comprehensive panel, and then go on to whole exome gene sequencing. Dr Grouse: That's really, really useful. Thank you so much for breaking that down in a really simple way that a lot of us can take with us. Pivoting a little bit now back towards different types of acquired ataxias, what are some typical lab tests that you recommend for that type of workup? Dr Zesiewicz: Again, if there's no genetic history and the person does not appear to have a neurodegenerative disease, we do test for acquired ataxias. Acquired ataxias can be complex. Many times, they are in the autoimmune family. So, what we start with are just basic labs like a CBC or a CMP, but then we tried to look at some of the other abnormalities that could cause ataxia. So, celiac disease, stiff person syndrome. So, you would look at anti-glutamic acid decarboxylase antibodies, Hashimoto's---so, antithyroglobulin antibodies or antithyroperoxidase antibodies would be helpful. You know, in a case of where the patients may have an underlying neoplasm, maybe even a paraneoplastic workup, such as an anti-Hu, anti-Yo, anti-Ri. A person has breast cancer, for example, you may want to take a paraneoplastic panel. I've been getting more of the anti-autoimmune encephalitis panels in some cases, that were- that are very interesting. And then, you know, things that sometimes we forget now like the syphilis test, thyroid-stimulating test, take a B12 and folate, for example. That would be important. Those are some of the labs. We just have on our electronic chart a group of acquired labs for ataxia. If we can't find any other reason, we just go ahead and try to get those. Dr Grouse: Now, I'm curious what you think is the most challenging aspect of diagnosing a patient with cerebellar ataxia? Dr Zesiewicz: So, for those of us who see many of these patients a day, some of the hardest patients are the ones that---regardless of the workup that we do, we've narrowed it down, it's not hereditary. You know, they've been through the whole exome gene sequencing and we've done the acquired ataxia workup. It doesn't appear to be that. And then we've looked for parkinsonism and neurodegenerative diseases, and it doesn't appear to be that either; like, the alpha-synuclein will be negative. Those are the toughest patients, where we think we've done everything and we still don't have the answer. So, I've had patients in whom I've taken care of family members years and years ago, they had a presumed diagnosis, and later on I've seen their children or other family members. And with the advent of the genetic tests that we have, like whole exome gene sequencing, we have now been able to give the patient and the family a definitive diagnosis that they didn't have 25 years ago. So, I would say don't give up hope. Retesting is important, and as science continues and we get more information and we make more landmark discoveries in genetics, you may be better able to diagnose the patient. Dr Grouse: I was wondering if you had any recommendations regarding either some tips and tricks, some pearls of wisdom you can impart to us regarding the work of ataxia, or conversely, any big pitfalls that you can help us avoid? I would love to hear about it. Dr Zesiewicz: Yeah, there's no easy way to treat or diagnose ataxia patients. I've always felt that the more patients you see- and sounds easy, but the more patients you see, the better you're going to become at it, and eventually things are going to fall into place. You'll begin to see similarities in patients, etc. I think it's important not only to make sure that a person has ataxia, but again, look at the other signs and symptoms that may point to ataxia that you'll see in a cerebellar syndrome. I think it's important to do a full neuroexam. If a person has spasticity, that may point you more towards a certain type of ataxia than if a person has no reflexes, for example, that we see in Friedreich's ataxia. Some of the ocular findings are very interesting as well. It's important to know if a person has a tremor. I've seen several Wilson's disease cases in my life with ataxia. They're very important. I think a full neuroexam and also a very detailed history would be very helpful. Dr Grouse: Tell us about some promising developments in the diagnosis and management of ataxia that we should be on the lookout for. Dr Zesiewicz: The first drug for Friedreich's ataxia was FDA-approved two years ago, which was an NRF2 activator, which was extremely exciting and promising. There are also several medications that are now in front of the FDA that may also be very promising and have gone through long clinical trials. There's a medication that's related to riluzole, which is a medication used for amyotrophic lateral sclerosis, that has been through about seven years of testing. That is before the FDA as well for spinal cerebellar ataxia. Friedreich's ataxia has now completed the first cardiac gene therapy program with AAV vectors, which- we're waiting for full results, but that's a cardiac test. But I would assume that in the future, neurological gene therapy is not far behind if we've already done cardiac gene therapy and Friedreich's ataxia. So, you know, some of these AAV vector-based genetic therapies may be very helpful, as well as ASO, antisense oligonucleotides, for example. And I think in the future, other things to think about are the CRISPR/Cas9 technology for potential treatment of ataxia. It is a very exciting time, and some major promising therapies have been realized in the past 2 to 3 years. Dr Grouse: Well, that's really exciting, and we'll all look forward to seeing these becoming more clinically applicable in the future. So, thank you so much for coming to talk with us today. Dr Zesiewicz: Thank you. Dr Grouse: Again, today I've been interviewing Dr Theresa Zesiewicz about her article on ataxia, which appears in the August 2025 Continuum issue on movement disorders. Be sure to check out Continuum Audio episodes from this and other issues, and thank you to our listeners for joining today. Dr Monteith: This is Dr Teshamae Monteith, Associate Editor of Continuum Audio. If you've enjoyed this episode, you'll love the journal, which is full of in-depth and clinically relevant information important for neurology practitioners. Use the link in the episode notes to learn more and subscribe. AAN members, you can get CME for listening to this interview by completing the evaluation at continpub.com/audioCME. Thank you for listening to Continuum Audio.
A collaborative study by the Clinic for Special Children in Lancaster and the Children’s Hospital of Philadelphia has identified an ultra-rare genetic disorder called complement factor I (CFI) deficiency, which is significantly more prevalent in individuals of Old Order Amish ancestry.Support WITF: https://www.witf.org/support/give-now/See omnystudio.com/listener for privacy information.
Michael Sobolik.Gordon Chang. China's Biowarfare Ambitions Threaten US Dominance and Global Health. China's Communist Party develops biowarfare, including ethnic-specific genetic attacks, to achieve strategic dominance over the US. China aims to divert US biotech innovation and control future vaccine distribution, leveraging lessons from COVID-19. US vaccine hesitancy and decreased investment in cutting-edge technology leave it dangerously exposed to future biothreats. 1906 PEKING DRUM TOWER
Genetic testing is more than just ancestry results. It can be one of the most powerful tools for supporting your child's long-term health and making informed medical decisions. In this empowering episode, Dr. Elana is joined by board-certified genetic counselor, Natalie Samson, to explore how DNA testing can help personalize everything from supplements to nutrition, vaccine protocols and emotional well-being. One of the most important parts of this conversation is how genetic insights can help assess vaccine risk. You'll learn how inflammation markers, methylation, detox pathways and oxidative stress genes can influence how a child responds to vaccines. With this information, parents can feel more confident in their ability to support their child's unique biology before and after vaccines. Natalie makes complex science feel easy to understand, offering real-life examples for moms who want clarity, not confusion. Dr. Elana also shares how genetic testing helped her tailor supplement plans, prepare for pregnancy and feel more grounded in her family's health decisions. Whether you are planning for pregnancy, navigating chronic symptoms, or facing vaccine decisions, this episode offers trusted education and encouragement so you feel informed and prepared. Topics Covered In This Episode: Genetic testing for personalized health plans How epigenetics influences chronic disease risk DNA-based vaccine risk assessment and immune support Understanding detox pathways and inflammation markers How genetic insights guide nutrition and supplement choices Supporting children's emotional health through neurotransmitter genetics Show Notes: Mention this podcast episode, and you can get 15% off an appointment with Natalie Follow @goldengeneticshealth on Instagram Click here to learn more about Dr. Elana Roumell's Doctor Mom Membership, a membership designed for moms who want to be their child's number one health advocate! Click here to learn more about Steph Greunke, RD's online nutrition program and community, Postpartum Reset, an intimate private community and online roadmap for any mama (or mama-to-be) who feels stuck, alone, and depleted and wants to learn how to thrive in motherhood. Listen to today's episode on our website Natalie is a dedicated Board-Certified Genetic Counselor devoted to transforming healthcare through personalized, integrative, and preventative approaches. She established her own practice, Golden Genetics to introduce an integrative and holistic approach to genetic counseling and testing, combining it with nutrition and nutrigenomics. She focuses on cancer, neurology and nutrigenomics and she aims to provide preventative and personalized care in genetic counseling and testing. This Episode's Sponsors Enjoy the health benefits of PaleoValley's products such as their supplements, superfood bars and meat sticks. Receive 15% off your purchase by heading to paleovalley.com/doctormom Discover for yourself why Needed is trusted by women's health practitioners and mamas alike to support optimal pregnancy outcomes. Try their 4 Part Complete Nutrition plan which includes a Prenatal Multi, Omega-3, Collagen Protein, and Pre/Probiotic. To get started, head to thisisneeded.com, and use code DOCTORMOM20 for 20% off Needed's Complete Plan! Active Skin Repair is a must-have for everyone to keep themselves and their families healthy and clean. Keep a bottle in the car to spray your face after removing your mask, a bottle in your medicine cabinet to replace your toxic first aid products, and one in your outdoor pack for whatever life throws at you. Use code DOCTORMOM to receive 20% off your order + free shipping (with $35 minimum purchase). Visit BLDGActive.com to order. INTRODUCE YOURSELF to Steph and Dr. Elana on Instagram. They can't wait to meet you! @stephgreunke @drelanaroumell Please remember that the views and ideas presented on this podcast are for informational purposes only. All information presented on this podcast is for informational purposes and not intended to serve as a substitute for the consultation, diagnosis, and/or medical treatment of a healthcare provider. Consult with your healthcare provider before starting any diet, supplement regimen, or to determine the appropriateness of the information shared on this podcast, or if you have any questions regarding your treatment plan.
For decades, we’ve been told that humans and chimpanzees are 99% genetically identical a claim repeated in museums, textbooks and by science celebrities like Bill Nye. But new genomic research tells a very different story. In this episode, Dr. Casey Luskin joins to reveal why the “1% difference” statistic is outdated, misleading, and scientifically inaccurate. We discuss how this number became one of evolution’s most popular talking points, why it persists despite being debunked, and what the latest studies actually show about human-chimp DNA. READ: Casey's Article: https://nypost.com/2025/07/26/opinion/smithsonian-exhibit-monkeys-around-with-the-scientific-evidence-on-human-origins/ *Get a MASTERS IN APOLOGETICS or SCIENCE AND RELIGION at BIOLA (https://bit.ly/3LdNqKf) *USE Discount Code [SMDCERTDISC] for 25% off the BIOLA APOLOGETICS CERTIFICATE program (https://bit.ly/3AzfPFM) *See our fully online UNDERGRAD DEGREE in Bible, Theology, and Apologetics: (https://bit.ly/448STKK) FOLLOW ME ON SOCIAL MEDIA: Twitter: https://x.com/Sean_McDowell TikTok: https://www.tiktok.com/@sean_mcdowell?lang=en Instagram: https://www.instagram.com/seanmcdowell/ Website: https://seanmcdowell.org Discover more Christian podcasts at lifeaudio.com and inquire about advertising opportunities at lifeaudio.com/contact-us.
“There is always a reason for illness. You may not have all your answers today, but that doesn't mean answers don't exist. Never give up.” – Dr. Diana DriscollIn this episode, Dr. Diana Driscoll — optometrist, researcher, patient, and founder of POTS Care — takes us inside her groundbreaking journey to uncover the hidden mechanisms of Postural Orthostatic Tachycardia Syndrome (POTS).After years of worsening illness and dismissal by the medical system, Dr. Driscoll combined her medical expertise with relentless patient-driven research. What emerged is now known as the Driscoll Theory, a framework that explores:What drives POTS: high intracranial pressure, vagus nerve dysfunction, neurotransmitter disruption, and systemic vascular irregularities.How to intervene: restoring vagus nerve function, reducing inflammation, supporting acetylcholine activity, and managing oxidative stress.Practical tools: supplements like ParaSym Plus and NAC Max, targeted use of histamine blockers, and non-invasive approaches to improving quality of life.Emotional resilience: how she navigated years of invalidation, supported her sick child, and created POTS Rebels, a community for patients seeking hope and science-backed solutions.This conversation is both deeply personal and highly practical, offering clarity for patients, practitioners, and caregivers searching for answers.00:00 – 02:00 | Intro & sponsor message (Healthgevity) Healthgevity our sponsor : Website Enter: ONETHING for a 10% discount02:00 – 03:00 | Adam introduces Dr. Driscoll & her personal journey with POTS03:00 – 08:00 | The turning point: realizing medicine had no answers → “I'm on my own”08:00 – 13:00 | Discovering high intracranial pressure and what eye patterns reveal14:00 – 18:00 | The emotional toll & why she built the POTS Rebels community19:00 – 24:00 | The what: inflammation as the hidden driver of POTS25:00 – 33:00 | The how: vagus nerve, acetylcholine, nicotine patch experiment, and ParaSym Plus34:00 – 38:00 | Genetic predisposition, hypermobility, and EDS connections38:00 – 41:00 | Identifying intracranial pressure symptoms (coat hanger pattern, nausea, insomnia)41:00 – 44:00 | Framework for healing: vagus support, histamine blockers, antioxidants45:00 – 48:00 | Take-home: “Never give up. Illness always has a reason.”49:00 | Closing thoughts & listener call-to-actionPOTS Care → potscare.comPOTS Rebels community → [Patreon link if available]TJ Nutrition (ParaSym Plus, NAC Max) → tjnutrition.comHealthgevity our sponsor : Website Enter: ONETHING for a 10% discount
BUFFALO, NY — September 9, 2025 — A new #research paper was #published in Volume 17, Issue 8 of Aging-US on August 1, 2025, titled “Causal relationships between gut microbiome and hundreds of age-related traits: evidence of a replicable effect on ApoM protein levels.” In this study, Federica Grosso, Daniela Zanetti, and Serena Sanna from the Institute for Genetic and Biomedical Research (IRGB) of the National Research Council (CNR), Italy, uncovered new associations between gut microbiome and the aging process. The researchers found that certain microbial characteristics may causally influence proteins in the blood linked to inflammation and heart health. These findings could help explain how age-related diseases like cardiovascular conditions and macular degeneration are influenced by changes in the gut ecosystem. The gut microbiome, the collection of microorganisms living in the digestive system, plays a major role in immune function and metabolic health. As people age, this microbial community shifts, often leading to imbalances associated with inflammation and chronic disease. To explore how these changes might affect the body, the researchers used Mendelian Randomization—a method that leverages genetic data—to test over 55,000 possible causal connections between gut microbial characteristics and age-related health indicators. The study identified 91 significant causal relationships. Among them, the researchers found that higher levels of certain gut bacteria were associated with increased risk of age-related macular degeneration. Another finding was the association between a metabolic pathway in the gut, called “purine nucleotides degradation II,” and lower levels of apolipoprotein M (ApoM), a protein that helps protect against heart disease. This result was validated using data from an independent study, strengthening the evidence. “Unlike previous studies, we performed replication analyses for the significant results using independent GWAS datasets, a fundamental step that has often been overlooked.” The study also revealed how some bacteria may affect protein levels differently depending on a person's blood type. Specifically, in individuals with blood type A, certain gut microbes that can break down a sugar called GalNAc may influence proteins related to inflammation and cardiovascular health. This suggests that personalized approaches to managing age-related diseases could consider both gut microbiota and genetic factors like blood type. The research team followed strict guidelines to reduce false findings and confirmed its key results in independent datasets. By carefully testing for reverse causality and other biases, the authors provided strong evidence that the gut microbiome can influence critical aspects of aging biology. Although more research is needed to fully understand the biological pathways involved, these findings suggest that targeting the gut microbiota might help delay or reduce age-related inflammation and disease. The study lays a foundation for future therapeutic strategies that could include diet, probiotics, or other microbiome-based interventions. DOI - https://doi.org/10.18632/aging.206293 Corresponding author - Serena Sanna - serena.sanna@cnr.it Abstract video - https://www.youtube.com/watch?v=CWky6jlHKUs Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts To learn more about the journal, please visit our website at https://www.Aging-US.com and connect with us on social media at: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Bluesky - https://bsky.app/profile/aging-us.bsky.social Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM
Why do conditions like MCAS, hEDS, POTS, autoimmunity, and chronic stress so often appear together? And more importantly...can they be reversed? In this episode, I sit down with Adrian Davidson, a writer and researcher exploring the intersections of health, wellness, politics, and pop culture. Adrian has a lifelong passion for storytelling and brings a perspective that is both critical and compassionate. She dives into everything from health theories to cultural phenomena, blending broader commentary with her own lived experiences on her socials.Adrian has reversed multiple complex conditions in her own life, including: Mast Cell Activation Syndrome (MCAS)Multiple Autoimmune conditionsAnemiaInfertilityHypothyroidismNarcolepsyAnxiety, OCD, ADHD, hallucinationsAutism and Gender DysphoriaIBSShe opens up about what it was like to live with these challenges, how they interconnected, and the steps she took to truly heal. We dive into:What the RCCX cluster is and how it links MCAS, POTS, hEDS, and moreThe connection between genes, trauma, and nervous system stressHow Adrian turned her own health around—moving from illness and infertility to resilience, thriving, and having her 3rd baby at 40.What you can do if you suspect these patterns are at play in your life✨ This episode blends science, lived experience, and hope. If you've ever felt “wired differently” or stuck in cycles of reactivity and illness, Adrian's story will show you that reversal and healing are possible. You can find her curating visual storytelling on Instagram @capitalism.and.glitter and sharing longer-form writing on her Substack. Substack:https://adriandavidson.substack.com/welcomeInstagram: https://www.instagram.com/capitalism.and.glitter/Copywrite @AmandaPanacea Lets work together!· https://thehealerrevolution.com/ · Learn about my testing and coaching services: https://youtu.be/U7o17WErb84si=aaDZyp7txO6txtzm · Free 15 mins clarity call https://l.bttr.to/cih5BMy Most popular Courses, Guides, and Product Referrals· Product Links https://shopmy.us/amandapanacea· Feel to Heal: Transform Triggers into Calm (My signature course): https://feeltoheal.co/ · MCAS and histamine intolerance guide https://www.feeltoheal.co/webinar-registration· How to Heal MCAS and Histamine Intolerance Webinar: https://l.bttr.to/3Qnmv · HolyHydrogen Molecular Hydrogen: https://holyhydrogen.com/Panacea · King Coffee (Reishi spore infused organic coffee): https://thehealerrevolution.myorganogold.com/en/premium-gourmet-king-of-coffee/ Are you a practitioner, coach, or want to be? · Get certified in Bioenergetic testing: https://bioenergetics.learnworlds.com...· Learn HTMA and sign up for the HTMA app: https://hairanalysis.report/ref/165/ · Learn how to use and source Peptides (for non practitioners also!): https://amandapanacea--designergenes.thrivecart.com/pepsquad/ · Functional Genomics and Epigenetics: https://thedesignergenesco.com/bbd?affiliate=amandapanacea · Learn to read Mold labs and OAT: https://amandapanacea.krtra.com/t/4yQ7W1qjLT9cBuy my 365 day Somatic Manifestation Journal: https://www.amazon.com/dp/B0CQNSKXWD#AdrenalFatigue #anxietyrelief #bioenergetics #neuroscience #brainretraining #somatichealing #ChronicStress #hrv #functionalfreeze #AdrenalSupport #fightflightfreeze #nervoussytemregulation #nervoussystem #bloodsugar #anxiety #burnout #functionalmedicine #htma #bioenergetictesting #mcas #eczema #lyme #moldillness #gutbrainconnection #lymedisease #mastcellactivationsyndrome #tsw #topicalsteroidwithdrawal #guthealth #mineralbalancing #circadianrhythms #mastcellactivation #frequencyhealing #allergyrelief #weightloss #peptides #stressrelief #traumahealing #peptidesforweightloss #Bioenergetictesting
Stephanie Rutledge joins host Saranya Ravindran to unpack the mental health dimensions of alcohol use disorder. From co-occurring conditions and behavioural strategies like motivational interviewing to the role of family and community support, this episode explores how integrated care can strengthen recovery. Timestamps: 1:44 – Why hepatology 3:25 – Genetic factors 4:18 – Alcohol use disorder interventions 5:58 – Motivational interviewing 7:25 – Motivational interviewing skills 8:34 – Beyond clinical settings 10:49 – Alcohol use disorder therapy
This week on Family Policy Matters, host Traci DeVette Griggs welcomes Dr. Marty McCaffrey, Professor of Pediatrics and Director of the Perinatal Quality Collaborative of North Carolina, to discuss how the medical community can improve care for babies born with genetic abnormalities.
The Genetic STandout Tour hosted by STgenetics® during the week of World Dairy Expo is coming up and joining us to give us some insight into what our visitors can expect from this experience is Kyle Demmer, the COO of GenoSource. Kyle shares how this year's tour is different from years past, why it's important for the three farms, GenoSource, Mormann Dairy and Farnear Holsteins, to host an event of this size, the progeny and families that will be on display and what genetics he thinks will impact the STgenetics® lineup in the next 5 years. This STtalks gives a glimpse into the fantastic operations STgenetics® has the opportunity to tour on September 30th!00:00 Introduction and Guest Introduction00:51 Overview of GenoSource and Its Role01:24 The Genetics STandout Tour02:34 GenoSource Farm Developments05:50 New Maternity Barn and IVF Center07:48 Genetic Highlights at GenoSource10:22 Insights on Mormann Dairy and Farnear Holstein12:00 Conclusion and Invitation to the Tour
When families first hear their child has OCD, many wonder if they somehow caused it. Dr. Evelyn Stewart has spent her career studying those fears — and the science tells a different story. She explains how research with families and twins shows that genes play a significant role, especially when OCD begins in childhood. Dr. Stewart also shares how environment and stress can act like switches, turning genetic risk “on” or “off.” This interview is packed with the latest research about all the links between OCD and genetics so be sure to watch til the end!Here at NOCD, we specialize in ERP therapy, the most effective therapy for OCD. To explore treatment options, book a free 15-minute call at https://learn.nocd.com/YTFollow us on social media:https://www.instagram.com/treatmyocd/https://twitter.com/treatmyocdhttps://www.tiktok.com/@treatmyocd Hosted on Acast. See acast.com/privacy for more information.
Dr. Kendal Stewart shares his unique perspective on Long Covid through his background as a surgeon with training in functional medicine, neurosurgery, and cell biology. His approach examines the body as an integrated system rather than separating it into isolated specialties.• Complex conditions like Long Covid require a holistic view of the body as an interconnected system• Western medicine often silos patients into specialties based on symptoms, missing the bigger picture• T-cell weakness and microglial activation are key factors in Long Covid symptoms• The body's inflammation is doing exactly what it's programmed to do—it's not broken• Northern Europeans have particularly aggressive genetics for inflammation (76%) and often have broken "off switches"• Peptides like thymusin alpha-1 can help recover exhausted T-cells• Creating an environment favorable for healing is more effective than treating individual symptoms• Genetic testing provides a personalized "map" for treatment, focusing only on what's missing• Many people who recover become healthier than they were before getting sickLinks: Dr Stewart's YoutubeDr Stewart's InstagramDr Stewart's websiteMessage the podcast! - questions will be answered on my youtube channel :) For more information about Long Covid Breathing courses & workshops, please check out LongCovidBreathing.com (music credit - Brock Hewitt, Rule of Life) Support the show~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~The Long Covid Podcast is self-produced & self funded. If you enjoy what you hear and are able to, please Buy me a coffee or purchase a mug to help cover costsTranscripts available on individual episodes herePodcast, website & blog: www.LongCovidPodcast.comFacebook @LongCovidPodcastInstagram Twitter @LongCovidPodFacebook Creativity GroupSubscribe to mailing listPlease get in touch with feedback, suggestions or how you're doing - I love to hear from you, via socials or LongCovidPodcast@gmail.com**Disclaimer - you should not rely on any medical information contained in this Podcast and related materials in making medical, health-related or other decisions. Please consult a doctor or other health professional**
In this episode, Dr. Harlan Krumholz reviews the September 9, 2025 issue of JACC, covering key studies on artificial intelligence in cardiovascular research, the effects of tirzepatide in heart failure with preserved ejection fraction (HFpEF), and how social, racial, and genetic factors influence heart failure risk. He discusses the growing burden of heart failure in the elderly, the need to disaggregate data in Asian American and Pacific Islander populations, and the role of rare genetic variants in atrial fibrillation outcomes. The episode also features perspectives on clinical trial design, complex case reports, and emphasizes the need for AI submissions to meet high standards of clinical relevance, feasibility, and long-term impact.
Too busy to read The Lens? Listen to our weekly summary here! In this week's episode we discuss:Genetic predisposition determined by polygenic risk score can predict glaucoma risk and visual field loss pattern.Patients receiving GLP-1 Receptor Agonists had a lower risk of developing uveitis.One-third of corneal perforations still required penetrating keratoplasty after glue treatment.
In this special episode, celebrating National Chicken Month, Dr. Sandro Cerrate, Poultry Nutrition Consultant, shares his insights on broiler breeder nutrition practices. He discusses how different countries approach poultry nutrition, the challenges posed by mycotoxins, and strategies for enhancing egg production and overall poultry health. Listen now on all major platforms!"The best recommendation for breeders is to measure and monitor feed and body condition regularly to ensure long-term production success."Meet the guest: Dr. Sandro Cerrate is a poultry nutritionist with extensive experience in both broiler breeders and layers. With a Ph.D. from the University of Arkansas, he has worked with major poultry companies and has been serving as a poultry nutrition consultant for over five years. His expertise spans global markets, with a focus on optimizing egg production and enhancing poultry health.Liked this one? Don't stop now — Here's what we think you'll love!What you'll learn:(00:00) Highlight(01:39) Introduction(02:15) Broiler breeder nutrition(03:39) Genetic selection and body condition(06:24) Addressing mycotoxins in feed(09:18) Alternative feed additives(11:47) Advice for broiler breeders(15:06) Closing thoughtsThe Poultry Nutrition Blackbelt Podcast is trusted and supported by innovative companies like:* Kemin* Kerry- Anitox- BASF- Poultry Science Association
This week on the Red Dirt Agronomy podcast, the crew sits down with Dusti Gallagher, CEO of Heartland Plant Innovations, to explore how cutting-edge breeding tools are transforming wheat genetics. From her Oklahoma upbringing to her role in driving biotech advancement in Kansas, Dusti shares the story of how HPI is helping breeders produce better wheat—faster. Using double haploid technology, her team can deliver pure, stable genetic lines in just a year, dramatically reducing development timelines.Dusti also introduces us to HB4 wheat, the first biotech wheat trait deregulated in the U.S., boasting drought tolerance and herbicide resistance. With a strong focus on science-backed innovation and a respect for producers' concerns about biotech, Dusti and HPI are helping bridge the gap between advanced research and on-farm value. Whether you're a grower or just fascinated by crop science, this is one conversation you won't want to miss.Key TakeawaysDouble-haploid technology significantly reduces breeding time—often by half.HPI specializes in creating pure wheat lines using early-generation F1 seeds.The corn pollination method is used to initiate the double haploid process.This method ensures genetic consistency without genetic modification.Wheat breeding is catching up to crops like corn in the use of advanced biotech tools.HPI supports both public and private breeding programs across the U.S. and internationally.Speed breeding techniques and environmental controls enhance breeding efficiency.Dusti Gallagher has deep roots in ag policy and wheat industry development.HB4 wheat introduces herbicide resistance and drought tolerance through biotech.HPI is positioning itself to manage biotech traits safely and transparently.Timestamps00:00 – Welcome and High Plains Journal Live intro00:42 – Meet Dusti Gallagher, CEO of Heartland Plant Innovations03:02 – What is double haploid technology?06:20 – How HPI cuts wheat breeding timelines in half08:22 – Speed breeding, single seed descent, and environmental control10:14 – Who HPI works with and what crops they support12:38 – Genetic complexity of wheat and challenges in breeding14:26 – GMO vs. double haploid breeding – clearing up confusion16:48 – Collaborating with breeders like Brett Carver18:19 – Dusti's journey from OSU to HPI21:03 – Is hybrid wheat finally here?22:09 – HB4 wheat: The first deregulated biotech trait in U.S. wheat24:34 – What's next for biotech in wheat breeding RedDirtAgronomy.com
Genetic genealogy is a field that combines traditional genealogy research with modern DNA testing techniques to trace familial relationships and ancestry through genetic information. It involves analyzing an individual's DNA to uncover their genetic heritage, connect with distant relatives, and map out family trees. This approach has gained significant popularity due to advancements in DNA sequencing technology, particularly in the form of direct-to-consumer DNA testing kits.Here's how genetic genealogy works and how it's used by investigators:DNA Testing: Individuals interested in exploring their genetic heritage and family history can submit their DNA samples through services provided by companies like AncestryDNA, 23andMe, and MyHeritageDNA. These companies analyze specific segments of the submitted DNA to identify genetic markers that are common among different populations and individuals.Genetic Markers: Certain sections of the DNA, particularly those found in the Y chromosome (passed from father to son) and the mitochondrial DNA (passed from mother to all offspring), contain genetic markers that can be used to identify ancestral lineages. Autosomal DNA, which is inherited from both parents, is also examined to find matches with other individuals in the testing company's database.Matching and Comparison: Testing companies compare an individual's genetic markers with those of other users in their databases. If two individuals share a significant amount of genetic material, they are considered genetic matches. The more segments of DNA they share, the closer their relationship is likely to be.Building Family Trees: Genetic genealogy involves constructing family trees using a combination of traditional genealogical research and the information gained from DNA matches. By connecting with other users who share segments of DNA, individuals can extend their family trees and discover new branches of their lineage.Identifying Common Ancestors: As more people participate in DNA testing, the chances of finding common ancestors increase. Overlapping segments of shared DNA can help identify specific ancestors or ancestral groups that are shared among related individuals.Forensic and Investigative Applications: Genetic genealogy has also found applications in criminal investigations. Law enforcement agencies have used DNA databases to identify unknown perpetrators of crimes like murder and sexual assault. In cases where traditional investigative methods have been unsuccessful, investigators can upload DNA profiles from crime scenes to genealogy databases and identify potential relatives of the suspect based on shared genetic markers.Building Family Trees for Identification: Once potential relatives of the suspect are identified, investigators work to build family trees using genealogical records, such as birth certificates, marriage records, and obituaries. By tracing the shared ancestry of these relatives, law enforcement can narrow down the list of potential suspects to a smaller pool.Narrowing Down Suspects: Investigative genetic genealogy can help law enforcement focus on specific individuals who fit the profile of the unknown suspect based on age, location, and other relevant factors. This process has led to the successful identification and capture of suspects in several high-profile cases.Bryan Kohberger's defense team has brought on Leah Larkin, a well respected genealogist to challenge the findings made by the prosecution during the DNA portion of the investigation. She will look to punch holes in the DNA evidence provided by the FBI and Moscow police and hopefully, from the defenses standpoint, provide a narrative that differs from the one presented by the prosecution. (commercial at 10:16)to contact me:bobbycapucci@protonmail.comsource:Bryan Kohberger update - genealogist hired by defense casts doubt on the reliability of genetic genealogy in Idaho murders investigation | Daily Mail OnlineBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-moscow-murders-and-more--5852883/support.
Host: Darryl S. Chutka, M.D. Guests: Thais D. Coutinho, M.D., and Kristen A. Sell-Dottin, M.D. Genetic factors predispose selected individuals to hereditary aortic aneurysms leading to aortic dilation and potential dissection. They can be seen in a variety of known genetic syndromes, and they differ from aortic aneurysms associated with aging and chronic, uncontrolled hypertension. Early recognition is critical in the management of these patients in preventing serious, often life-threatening aortic dissection. How common are hereditary aortic aneurysms? When and how should we screen patients for this condition? Is a genetic consultation recommended? When should we involve a vascular surgeon when at risk patients are identified? These are some of the questions I'll be asking my guests, Thais D. Coutinho, M.D., a cardiologist and cardiac surgeon, Kristen A. Sell-Dottin, M.D., both from the Mayo Clinic. We'll be discussing “Hereditary Aortic Aneurysms and Dissection” as part of our podcast series on “Peripheral Vascular Disease”. Mayo Clinic Talks: Vascular Medicine Series | Mayo Clinic School of Continuous Professional Development Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts
Is your fertility struggle really about MTHFR—or could your genes be pointing to a much bigger story?If you've ever been told that an MTHFR mutation explains why you can't conceive—or if you've tried all the “clean living” advice and still aren't seeing results—this episode is for you. We explore how genetics, oxidative stress, and hidden nutrient weaknesses can quietly impact egg and sperm health, making pregnancy feel out of reach even when you're doing everything “right.”In this episode, you'll learn...-Why MTHFR is only one piece of the fertility puzzle and what else you must consider.-How oxidative stress and genetic predispositions directly influence egg and sperm quality.-The role of functional genetic testing in uncovering hidden causes of unexplained infertility and guiding personalized solutions.Press play now to uncover how your genes and environment interact—and how this knowledge can finally move you closer to growing the family of your dreams.
Dr. Dillon Pruett has lived both sides of stuttering: the anxious kid rehearsing every word and the scientist searching DNA for answers. His groundbreaking research, recently published in Nature Genetics, uncovered 57 genetic hotspots tied to stuttering -- proof that our voices carry a biological story as complex as any human trait. In our conversation, Dillon shares how his personal journey shaped his path into research, what the findings reveal about stuttering's overlap with traits like musicality and sleep, and why the goal isn't to “fix” stuttering but to demystify it. At its heart, this episode is about turning stigma into science and science back into compassion.You can read the study here. -----
In this Labor Day episode, Brad highlights the history of the holiday in the U.S. and Canada before diving into a brand-new genetic evaluation for Holstein dairy cattle: milking speed. Released in August 2025, this trait provides an objective way to measure how quickly cows milk—expressed in pounds of milk per minute—with the Holstein breed average set at 7 lbs/min.Brad explains how this evaluation was developed using parlor sensor data (not robot milking systems) from over 165 herds and 43,000 cows, making it more accurate than traditional subjective scoring methods used in other breeds. With heritability at 42%, milking speed is a promising selection tool for improving parlor efficiency and labor use.The episode also covers:How milking speed correlates with traits like somatic cell score and mastitis.The range of variation in bulls and what that means for selection decisions.Why milking speed isn't yet included in the lifetime merit index.Practical implications for farmers considering faster vs. slower milking cows.Brad wraps up by reflecting on how this new tool could impact herd management at the Morris research herd and encourages producers to watch for milking speed in future bull proofs.Questions, comments, scathing rebuttals? -> themoosroom@umn.edu or call 612-624-3610 and leave us a message!Linkedin -> The Moos RoomTwitter -> @UMNmoosroom and @UMNFarmSafetyFacebook -> @UMNDairyYouTube -> UMN Beef and Dairy and UMN Farm Safety and HealthInstagram -> @UMNWCROCDairyExtension WebsiteAgriAmerica Podcast Directory
#surrogacy #ivf #surrogate Paying It Forward Instagram: https://www.instagram.com/payingitforward_surrogacy?igsh=NTc4MTIwNjQ2YQ==Beth Moskowicz journey through surrogacy began over a decade ago when she and her husband faced fertility challenges. After failed IVF transfers and a heartbreaking miscarriage, they turned to surrogacy—a path that would not only build their family but eventually shape Beth's career and life purpose.What started as her personal quest for parenthood evolved into a profound mission to help others. Beth candidly shares the dramatic birth of her daughter, where a rare umbilical cord complication led to moments of terror before joy. Three years later, after unsuccessful transfer attempts with their first surrogate, they matched with another surrogate who carried their son to term. These experiences gave Beth unique insight into both the emotional rollercoaster and practical realities of surrogacy journeys.The technological advancements Beth witnessed between her children's births—just three years apart—highlight how rapidly the field evolves. Genetic testing of embryos, unavailable during her daughter's journey, became standard practice by the time her son was conceived, fundamentally changing success rates and risk factors.Today, as founder of Paying it Forward Surrogacy, Beth deliberately maintains a boutique approach, personally managing no more than seven cases at once. This allows her to provide the kind of attentive support she valued during her own surrogacy experiences. Her background as both a newspaper reporter and law school graduate equips her with exceptional communication skills and legal understanding—though she's quick to clarify she doesn't write contracts herself.Beth offers valuable perspective on the changing landscape of surrogacy compensation and state legislation, particularly regarding pregnancy termination rights. Her balanced approach acknowledges both surrogate worth and the financial realities faced by intended parents. Above all, she emphasizes the critical importance of thorough research, clear communication, and addressing concerns promptly rather than letting them fester.Connect with Beth at payingitforwardsurrogacy.com to learn how her uniquely personal approach might support your surrogacy journey. Instagram: Stop.Sit.Surrogate TikTok: Stop.Sit.Surrogate Send us a textTwo Awesome PeopleNew Episodes Every Monday and Thursday!Listen on: Apple Podcasts Spotifyhttps://stopsitsurrogate.com
In this episode of The Lindsay Elmore Show, Lindsay sits down with David Roberts, co-founder of Mara Labs and a pioneer in sulforaphane supplementation.Sulforaphane, derived from broccoli sprouts, has been called the "master molecule for health" thanks to its ability to support detoxification, reduce inflammation, enhance brain health, and improve metabolic function. David shares the science behind stabilizing sulforaphane, explains why most supplements fall short, and discusses its synergistic effects with molecules like curcumin. From detoxing microplastics to balancing hormones and boosting mitochondrial energy, sulforaphane has far-reaching benefits for overall resilience.Key TakeawaysSulforaphane Basics: A compound found in broccoli sprouts with over 37 documented pro-health mechanisms.Brain Health: Increases BDNF, supporting neuroprotection, neurogenesis, and even enhanced dreaming.Detoxification: Activates NRF2 pathways, turning on over 200 antioxidant and detox genes for up to 72 hours.Inflammation: Synergizes with curcumin to reduce NF-kB and IL-6, two key pro-inflammatory markers.Practical Use: Each capsule of Mara Labs' stabilized sulforaphane equals the benefit of 2.5 pounds of broccoli.Metabolic Impact: Helps balance estrogen, supports mitochondrial energy, and assists in reducing belly fat and insulin resistance.Environmental Defense: Aids the body in processing toxins like glyphosate and mobilizing microplastics.Chapter Timestamps01:00 – What is sulforaphane and why it's the “master molecule”03:00 – How sulforaphane supports brain health through BDNF05:00 – Stabilizing sulforaphane and the challenges of supplementation06:45 – David's personal story: breast cancer diagnosis and discovery of sulforaphane08:00 – How sulforaphane is delivered and stabilized in capsules10:00 – The NRF2 pathway and turning on antioxidant defense13:00 – Detox done right: why many “detox programs” fail15:00 – Curcumin and sulforaphane synergy for inflammation reduction18:00 – Internal studies on inflammation markers (IL-6, NF-kB)20:00 – The real role of detoxification vs. buzzwords24:00 – Toxins in modern life: microplastics, glyphosate, and more28:00 – Genetic modification, glyphosate, and long-term toxicity29:30 – Sulforaphane for metabolism, mitochondrial energy, and belly fat32:00 – Additional Mara Labs products supporting metabolism (GLP-1 alternatives)33:00 – How to learn more: Mara Labs discount link
In this episode of The Select Sires Podcast, host Ethan Haywood sits down with Patrick Maier and Max Shenkenberg of Maier Farms, and Susie Martin from CentralStar Cooperative to take a deep dive into how strategic genetics, disciplined reproductive protocols, and a strong team culture have positioned Maier Farms as a leader in reproductive performance, earning them a CentralStar ReproStar Award in 2025. With insights on fertility management, bull selection, data-driven decisions, and the importance of patience in genetic progress, this episode is packed with practical takeaways for any producer looking to improve cow longevity and herd performance.
Cancer isn't just random genetic mutations. It doesn't “just happen.” In this episode, Dr. Connealy pulls back the curtain on what really drives cancer — from mitochondrial breakdown and hidden toxins to stress, parasites, and even low voltage inside your cells. You'll learn how to hack your environment, strengthen your biology, and prevent disease years before a tumor ever shows up on a scan. Dr. Leigh Erin Connealy, MD, is one of the most sought-after integrative oncologists in the world. She runs the Cancer Center for Healing and the Center for New Medicine, where she's been upgrading patient outcomes for nearly four decades. Her new book, The Cancer Revolution, gives you the tools to take back control of your biology and stop cancer before it starts.What You'll Discover
Your neck is the highway from your brain to your body, and one small instability (even if you don't feel it) can create a whirlwind of issues in your body below it: from low energy to gut issues, hip or knee pain, a weakened immune system, poor sleep, bad moods and so much more. But what no one talks about is how you're likely dealing with this silent neck problem and how one simple movement or adjustment can correct this whole cascade of events that's slowly strangling the health and viltality out of your body. TOPICS DISCUSSED IN THIS EPISODE: The role of neck and nerve function in gut health, stomach acid and enzyme production, gut motility and leaky gut How neck misalignment (C1 instability) creates pain down below How to make treatments and adjustments last Genetic factors weakening your connective tissues Complimentary therapies to stiffen ligaments so your adjustments and joints hold Practical steps to give to your own health care providers More from Erin Doppelt: Instagram: @drryanemmons Clinic Website: atlaspaicentre.com C1 Course for Professionals: clinicalupgrade.ca Leave us a Review: https://www.reversablepod.com/review Need help with your gut? Visit my website gutsolution.ca to join a program: Get help now Contact us: reversablepod.com/tips FIND ME ON SOCIAL MEDIA: Instagram Facebook YouTube
Have you ever felt like you're doing everything right—eating clean, taking your supplements, exercising, sleeping—and yet, something still feels off? In this episode, I'm diving deep into one of the most overlooked but essential processes in your body: methylation. It might sound like something from chemistry class (and technically it is), but it affects everything—from your energy and hormones to detox, mental health, and even how your genes show up in real life. If you've heard of MTHFR or suspect there's something going on under the surface that no one has been able to explain… this is for you. Here's What I Cover in This Episode: What methylation actually is—and why it matters for your overall health The connection between methylation and your detox, mood, hormones, and energy Signs you might be struggling with methylation (hint: it's way more common than you think) Why the phrase “genetics load the gun, lifestyle pulls the trigger” applies to your health journey What MTHFR, COMT, PEMT, MTRR, and other gene variants mean for your body Why some supplements might not work for you—and how to choose the ones that actually do My personal experiences with poor methylation (including that dental numbing story
Dr. Natalie Crawford breaks down everything you need to know about your eggs - how many you have, how good they are, and what age really means for your fertility. She explains the difference between egg quality and quantity, how your ovarian reserve is tested, and practical steps you can take to support your egg health at any age. Key Topics: 1. Understanding Your Egg Supply - The natural decline of eggs from birth through menopause - How the monthly egg release system works in your ovaries - Do you lose eggs even when not ovulating or trying to conceive? 2. Testing Your Fertility Potential - AMH blood test and what it measures in your body - Antral follicle count ultrasound examination process - How these tests relate to your remaining egg supply 3. How Age Affects Your Eggs - The relationship between time and egg quality deterioration - Genetic changes that occur in eggs as you get older - Why pregnancy becomes more difficult after age 35 4. Taking Control of Your Egg Health - Lifestyle factors that influence egg quality - The role of inflammation in reproductive health - How diet, stress, and environmental toxins impact fertility Pre-order Dr. Crawford's debut book, The Fertility Formula, now! https://www.nataliecrawfordmd.com/book Want to receive my weekly newsletter? Sign up at nataliecrawfordmd.com/newsletter to receive updates, Q&A, special content, and freebies If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every Tuesday. Plus, be sure to follow along on Instagram @nataliecrawfordmd, check out Natalie's YouTube channel Natalie Crawford MD, and if you're interested in becoming a patient, check out Fora Fertility. Join the Learn at Pinnacle app to earn FREE CE Credit for listening to this episode! This episode is brought to you by The Pinnacle Podcast Network! Learn more about Pinnacle at learnatpinnacle.com Learn more about your ad choices. Visit megaphone.fm/adchoices
CardioNerds (Drs. Rick Ferraro and Georgia Vasilakis Tsatiris) discuss ATTR cardiac amyloidosis with expert Dr. Justin Grodin. This episode is a must-listen for all who want to know how to diagnose and treat ATTR with current available therapies, as well as management of concomitant diseases through a multidisciplinary approach. We take a deep dive into the importance of genetic testing, not only for patients and families, but also for gene-specific therapies on the horizon. Dr. Grodin draws us a roadmap, guiding us through new experimental therapies that may reverse the amyloidosis disease process once and for all. Audio editing by CardioNerds academy intern, Christiana Dangas. This episode was developed in collaboration with the American Society of Preventive Cardiology and supported by an educational grant from BridgeBio. Enjoy this Circulation Paths to Discovery article to learn more about the CardioNerds mission and journey. US Cardiology Review is now the official journal of CardioNerds! Submit your manuscripts here. CardioNerds Cardiac Amyloid PageCardioNerds Episode Page Pearls: You must THINK about your patient having amyloid to recognize the pattern and make the diagnosis. Start with a routine ECG and TTE, and look for a disproportionately large heart muscle with relatively low voltages on the ECG. Before you diagnose ATTR amyloidosis, AL amyloidosis must be ruled out (or ruled in) with serum light chains, serum/urine immunofixation, and/or tissue biopsy. Genetic testing is standard of care for all patients and families with ATTR amyloidosis, and the future is promising for gene-specific treatments. Current FDA-approved treatments for TTR amyloidosis are TTR stabilizers and TTR silencers, but TTR fibril-depleting agents are on their way. Early diagnosis of ATTR affords patients maximal benefit from current amyloidosis therapies. TTR amyloidosis patients require a multidisciplinary approach for success, given the high number of concomitant diseases with cardiomyopathy. Notes: Notes: Notes drafted by Dr. Georgia Vasilakis Tsatiris. What makes you most suspicious of a diagnosis of cardiac amyloidosis from the typical heart failure patient? You must have a strong index of suspicion, meaning you THINK that the patient could have cardiac amyloidosis, to consider it diagnostically. Some characteristics or “red flags” to not miss: Disproportionately thick heart muscle with a relatively low voltages on EKG Bilateral carpal tunnel syndrome – estimated that 1 in 10 people >65 years old will have amyloidosis Previously tolerated antihypertensive medications Atraumatic biceps tendon rupture Bilateral carpal tunnel syndrome Spinal stenosis Concomitant with other diseases: HFpEF, low-flow low-gradient aortic stenosis How would you work up a patient for cardiac amyloidosis? Start with a routine ECG (looking for disproportionally low voltage) and routine TTE (looking for thick heart muscle) CBC, serum chemistries, hepatic function panel, NT proBNP, and troponin levels NOTE: It is critical to differentiate between amyloid light chain (AL amyloidosis) and transthyretin ATTR amyloidosis, as both make up 95-99% of amyloidosis cases. Obtain serum free light chains, serum & urine electrophoresis, and serum & urine immunofixation to rule out AL amyloidosis. (See table below) AL Amyloidosis ATTR Amyloidosis → Positive serum free light chains and immunofixation (Abnormal M protein) → Tissue biopsy (endomyocardial, fat pad) to confirm diagnosis → Negative serum free light chains and immunofixation (ruled out AL amyloidosis) → Cardiac scintigraphy (Technetium pyrophosphate with SPECT imaging) What treatment options do we have to offer now for ATTR CM, and how has this compared to prior years? Before 2019, treatment options were limited outside of cardiac tr...
My guest is Dr. Sergiu Pașca, MD, professor of psychiatry and behavioral sciences at Stanford University. We discuss the biology and genetics of autism, why autism diagnoses are increasing and recent progress in using stem cells to understand and treat profound autism and other brain disorders. Dr. Pașca explains “organoids and assembloids”—human stem cell–derived tools he pioneered to study, treat and cure complex brain diseases. We also discuss ethical and safety issues with using gene editing and stem cells in humans. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman David: https://davidprotein.com/huberman Helix: https://helixsleep.com/huberman BetterHelp: https://betterhelp.com/huberman Function: https://functionhealth.com/huberman Timestamps (00:00) Sergiu Pașca (02:08) Autism Spectrum Disorder, Incidence, Genetics (07:16) Is Autism More Common in Males? (09:35) Sponsors: David & Helix Sleep (11:56) Eye Contact in Babies, Fever; Proposed Causes of Autism; Genes (18:48) Genetic or Idiopathic Autism Diagnoses, Timothy Syndrome (21:37) Rise in Autism Diagnoses (26:46) Cause, Correlation & Neurological Disease; Schizophrenia, Do Vaccines Cause Autism? (31:34) Global Increase in Autism; Gene Therapy, CRISPR, Follistatin (41:05) Sponsors: AG1 & BetterHelp (43:41) Stem Cells, Ethics, Yamanaka Factors, Human Stem Cell Models (52:03) Umbilical Stem Cells; Stem Cell Injections & Dangers, Autistic Kids (59:30) Organoids, Modeling Brain Development, Intrinsic Development Timer (1:12:22) Assembloids, Brain Cell Migration & Circuit Formation, Self-Organization (1:21:22) Four-Part Assembloid, Sensory Assembloid, Pain Conditions (1:25:45) Sponsor: Function (1:27:33) Future Medical Therapies, Cell Banking, Immortalize Tissues, Rejuvenate Cells (1:34:56) Assembloids & Ethics, Importance of Nomenclature, Science Collaboration & Self-Correction (1:45:38) Cell Transplantation & Ethics, Timing (1:55:05) Genetic Testing for Parents, Genetic Penetrance (2:02:36) Assembloids, Timothy Syndrome, Epilepsy, Schizophrenia, Dystonia (2:14:30) Scientific Career, Walking, Art, Medical School (2:20:44) Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices
About this episode: Sickle cell disease affects an estimated 100,000 people in the United States. Recent advancements in gene therapies and medicines like hydroxyurea are diminishing extreme pain, reducing strokes, and extending survival times for those afflicted by the disease. In this episode: leading sickle cell disease expert Dr. Mark Gladwin explains how revolutionary new treatments work and discusses the challenges to access to life-saving care. Guest: Dr. Mark Gladwin is a physician-scientist and the Dean of the University of Maryland School of Medicine and Vice President for Medical Affairs at the University of Maryland, Baltimore. His research focuses include sickle cell disease and hypertension. Host: Dr. Josh Sharfstein is vice dean for public health practice and community engagement at the Johns Hopkins Bloomberg School of Public Health, a faculty member in health policy, a pediatrician, and former secretary of Maryland's Health Department. Show links and related content: New sickle cell gene therapies are a breakthrough, but solving how to pay their high prices is a struggle—CNBC Gene Therapy: What You Need to Know—Sickle Cell Disease Association of American No More Pain: Breakthrough Sickle Cell Treatment from Johns Hopkins Offers Curative Potential—Johns Hopkins School of Medicine Transcript information: Looking for episode transcripts? Open our podcast on the Apple Podcasts app (desktop or mobile) or the Spotify mobile app to access an auto-generated transcript of any episode. Closed captioning is also available for every episode on our YouTube channel. Contact us: Have a question about something you heard? Looking for a transcript? Want to suggest a topic or guest? Contact us via email or visit our website. Follow us: @PublicHealthPod on Bluesky @JohnsHopkinsSPH on Instagram @JohnsHopkinsSPH on Facebook @PublicHealthOnCall on YouTube Here's our RSS feed Note: These podcasts are a conversation between the participants, and do not represent the position of Johns Hopkins University.
Send us a textWe recently met up with our good friend and brother in Christ, Scott Mitchell from the Bible Mysteries podcast for a deep iron sharpening conversation. This is a special crossover episode in which we will be releasing the show at the same time to both our audiences. Please check out the Bible Mysteries Podcast: https://www.biblemysteriespodcast.com/SUPPORT THE SHOWBuy Me A Coffee http://buymeacoffee.com/DangerousinfopodcastSubscribeStar http://bit.ly/42Y0qM8Super Chat Tip https://bit.ly/42W7iZHBuzzsprout https://bit.ly/3m50hFTPaypal http://bit.ly/3Gv3ZjpPatreon http://bit.ly/3G3 SMART is the acronym that was created by technocrats that have setup the "internet of things" that will eventually enslave humanity to their needs. Support the showCONNECT WITH USWebsite https://www.dangerousinfopodcast.com/Guilded Chatroom http://bit.ly/42OayqyEmail the show dangerousinfopodcast@protonmail.comJoin mailing list http://bit.ly/3Kku5YtSOCIALSInstagram https://www.instagram.com/dangerousinfo/Twitter https://twitter.com/jaymz_jesseGab https://gab.com/JessejaymzTruth Social https://truthsocial.com/@jessejaymzWATCH LIVE YouTube https://www.youtube.com/@DANGEROUSINFOPODCASTRumble https://rumble.com/c/DangerousInfoPodcast Twitch https://www.twitch.tv/dangerousinfopodcastPilled https://pilled.net/profile/144176Facebook https://www.facebook.com/DangerousInfoPodcast/BitChute: https://www.bitchute.com/channel/egnticQyZgxDCloutHub https://clouthub.com/DangerousINFOpodcastDLive https://...
This Gene's a Real MTHFR—Here's What It's Doing to Your Body This episode unpacks the powerful effects of the MTHFR gene mutation—on your heart, liver, brain, and mood. Learn how this tiny genetic hiccup can impact energy, detox pathways, mental health, and longevity—and what to do if you've got it. 5 KEY TAKEAWAYS Heart Disease Connection – MTHFR mutations elevate homocysteine, increasing risk for arterial inflammation, stroke, and dementia. Liver Strain – MTHFR dysfunction contributes to fatty liver and reduces the body's ability to detox. Glutathione Production – The gene impacts your ability to make antioxidants like glutathione and NAC, which protect against oxidative stress. Mood & Mental Health – MTHFR affects neurotransmitter production, especially serotonin and dopamine, increasing risk of depression and ADHD. You Need Methyl Donors – Supplements like methylfolate, P-5-P, SAMe, and betaine are crucial to bypass genetic bottlenecks and restore methylation function. FEATURED PRODUCT Bliss, featuring SAMe and betaine (trimethylglycine), supports healthy methylation by donating methyl groups—essential for mood, energy, and detox. With sublingual delivery for rapid absorption, Bliss is ideal for those with MTHFR mutations needing extra support for neurotransmitter production, glutathione synthesis, and liver detox. A must-have if you struggle with low mood, brain fog, or inflammation. Get it here: https://www.mswnutrition.com/products/bliss TIMESTAMPS 00:00 START – Welcome to the School of Doza 01:00 – Introducing the MTHFR gene and its reputation 02:00 – Genetic testing and what a consult reveals 03:00 – Homocysteine, inflammation, and heart disease 05:00 – Nitric oxide, artery stiffness, and dementia risk 07:00 – Why everyone should test for MTHFR and homocysteine 08:00 – The liver's overlooked connection to MTHFR 09:30 – How inflammation triggers liver enzymes 11:00 – Why even "normal" genes need lifestyle support 12:00 – Folate (B9) deficiency and its link to depression 13:30 – Personal story: low folate, high homocysteine, and recovery 14:30 – MTHFR, liver enzymes, and antioxidant production 16:00 – Glutathione and NAC: made in the liver, suppressed by MTHFR 18:00 – Methylation, DNA repair, and cancer risk 20:00 – GGT as a liver marker for oxidative stress 21:00 – Neurotransmitters and the B vitamins behind serotonin 22:00 – MTHFR, ADHD, and mental health 23:00 – How Bliss supports brain function and neurotransmitters 25:00 – Methyl donors vs. methylated B12 shots 26:30 – Why Bliss works better for many than other B complexes 27:00 – Research on betaine and SAMe: brain, mood, addiction 30:00 – Methylation and NAD, COMT, and why Bliss helps both 32:00 – Final thoughts: lifestyle can suppress even a “normal” gene RESOURCES MTHFR Overview: https://www.ncbi.nlm.nih.gov/books/NBK66131/ Homocysteine and Heart Disease: https://pmc.ncbi.nlm.nih.gov/articles/PMC12027316/ GGT, Liver, and Glutathione: https://pmc.ncbi.nlm.nih.gov/articles/PMC2696075/ Antioxidants and Diabetes Risk: https://pubmed.ncbi.nlm.nih.gov/39442756/ Neurotransmitters and Depression: https://pmc.ncbi.nlm.nih.gov/articles/PMC4750636/ Methyl Donors and Mental Health: https://pmc.ncbi.nlm.nih.gov/articles/PMC10556504/ Betaine for Addiction and Mood: https://www.sciencedirect.com/science/article/abs/pii/S0278584624001611
BREEDERS SYNDICATE MERCH NOW AVAILABLE!https://www.syndicategear.comCheck out our BuyMeACoffee to Access Our Discord & Membership Plan Here:https://www.buymeacoffee.com/matthewriotBREEDERS SYNDICATE LINKS: https://linktr.ee/riotseedsFollow us on Twitch!https://www.twitch.tv/thebreederssyndicateCheck out our STRAIN DATABASE aka CODEX: https://codex.thebreederssyndicate.com/Copyright Disclaimer: The material contained herein is used under the doctrine of 'fair use' pursuant to Section 107 of the U.S. Copyright Act, allowing for limited use of copyrighted material for criticism, comment, news reporting, teaching, scholarship, and research. All rights reserved to the original copyright holders.Intro / Outro courtesy of:Sight of Wonders / Approaching the Middle East / courtesy of www.epidemicsound.com#breederssyndicate #cannaluminati #riotseeds #blueberry #strainhistory #cannabis #education #chemdog #chuckypollens #weedpodcast Want to create live streams like this? Check out StreamYard: https://streamyard.com/pal/d/5591549961568256Become a supporter of this podcast: https://www.spreaker.com/podcast/breeders-syndicate-3-0--5630034/support.
In today's episode, you will hear an interesting English story. As you listen to the story, you will also learn a series of English terms that are connected to a specific topic. This lesson will help you improve your ability to speak English fluently about a specific topic. It will also help you feel more confident in your English abilities.Story Title“The Digital Lifeline”5 Vocabulary WordsTelemedicine: (noun) The remote delivery of healthcare services, such as diagnosis, consultation, and treatment.Example sentences: Telemedicine has become increasingly popular in recent years.Telemedicine appointments can be more convenient for patients.Telemedicine can help to reduce healthcare costs.Genetic Engineering: (noun) The deliberate modification of an organism's genome using genetic engineering techniques.Example sentences: Genetic engineering can be used to treat genetic diseases.Genetic engineering raises ethical concerns about the manipulation of life.Genetic engineering has the potential to improve crop yields and resistance to pests.Telehealth: (noun) The use of digital information and communication technologies to provide health care services.Example sentences: Telehealth can improve access to healthcare, especially in rural areas.Telehealth appointments can be more convenient and cost-effective for patients.Telehealth can be used for a variety of healthcare services, including mental health counseling and chronic disease management.Remote Patient Monitoring: (noun) The use of technology to monitor a patient's health status from a distance.Example sentences: Remote patient monitoring can help to prevent hospitalizations.Remote patient monitoring devices can track vital signs and other health metrics.Remote patient monitoring can improve patient outcomes and reduce healthcare costs.Precision Medicine: (noun) A form of medicine that uses information about a patient's genes, proteins, and environment to prevent, diagnose, and treat disease.Example sentences: Precision medicine can lead to more effective and personalized treatments.Precision medicine requires advanced genetic testing and analysis.Precision medicine has the potential to revolutionize healthcare.If you want to sign up for the free daily English vocabulary newsletter, go towww.dailyenglishvocabulary.com
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James Tytko explores the science behind 'three-parent' embryos: the incredible medical procedure that prevents children from inheriting incurable mitochondrial diseases. Like this podcast? Please help us by supporting the Naked Scientists
Dr. Latt Mansor, Oxford PhD and Research Lead at H.V.M.N., joins Dr. Will Cole to break down everything you need to know about ketones, metabolism, and longevity. From brain performance and recovery to reversing metabolic disease, they explore how ketones can support energy, cognition, and healing. Dr. Mansor also shares his personal health journey and what the future of metabolic tracking could mean for all of us. For all links mentioned in this episode, visit http://www.drwillcole.com/podcastPlease note that this episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct or indirect financial interest in products or services referred to in this episode.Sponsors:Save 30% off your first subscription order & receive a free six pack of Ketone-IQ with KETONE.com/WILLCOLEProduced by Dear Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Episode 4690: Smoking Gun Behind Obama's CIA Claims; Experimental Genetic Products
Jack Weatherford is an anthropologist and historian specializing in Genghis Khan and the Mongol Empire. Thank you for listening ❤ Check out our sponsors: https://lexfridman.com/sponsors/ep476-sc See below for timestamps, and to give feedback, submit questions, contact Lex, etc. CONTACT LEX: Feedback - give feedback to Lex: https://lexfridman.com/survey AMA - submit questions, videos or call-in: https://lexfridman.com/ama Hiring - join our team: https://lexfridman.com/hiring Other - other ways to get in touch: https://lexfridman.com/contact EPISODE LINKS: Jack's Books: https://amzn.to/3ISziZr Genghis Khan and the Making of the Modern World: https://amzn.to/4l45LsY The Secret History of the Mongol Queens: https://amzn.to/4l22uud Genghis Khan and the Quest for God: https://amzn.to/4fpOQA4 Emperor of the Seas: Kublai Khan and the Making of China: https://amzn.to/40JEll1 SPONSORS: To support this podcast, check out our sponsors & get discounts: Allio Capital: AI-powered investment app that uses global macroeconomic trends. Go to https://alliocapital.com/ ZocDoc: App that helps patients find healthcare providers. Go to https://zocdoc.com/lex Fin: AI agent for customer service. Go to https://fin.ai/lex Oracle: Cloud infrastructure. Go to https://oracle.com/lex Shopify: Sell stuff online. Go to https://shopify.com/lex MasterClass: Online classes from world-class experts. Go to https://masterclass.com/lexpod LMNT: Zero-sugar electrolyte drink mix. Go to https://drinkLMNT.com/lex OUTLINE: (00:00) - Introduction (00:44) - Sponsors, Comments, and Reflections (10:44) - Origin story of Genghis Khan (52:30) - Early battles & conquests (1:05:11) - Power (1:07:33) - Secret History (1:20:58) - Mongolian steppe (1:24:16) - Mounted archery and horse-riding (1:32:36) - Genghis Khan's army (1:48:49) - Military tactics and strategy (2:01:13) - Wars of conquest (2:05:37) - Dan Carlin (2:15:37) - Religious freedom (2:31:24) - Trade and the Silk Road (2:40:10) - Weapons innovation (2:41:40) - Kublai Khan and conquering China (3:23:31) - Fall of the Mongol Empire (3:50:26) - Genetic legacy (4:00:20) - Lessons from Genghis Khan (4:10:36) - Human nature (4:13:47) - Visiting Mongolia (4:33:15) - Lex: Dan Carlin (4:36:06) - Lex: Gaza PODCAST LINKS: - Podcast Website: https://lexfridman.com/podcast - Apple Podcasts: https://apple.co/2lwqZIr - Spotify: https://spoti.fi/2nEwCF8 - RSS: https://lexfridman.com/feed/podcast/ - Podcast Playlist: https://www.youtube.com/playlist?list=PLrAXtmErZgOdP_8GztsuKi9nrraNbKKp4 - Clips Channel: https://www.youtube.com/lexclips
President Trump explains how tariffs work and how they're already working. Update on the continuing deportation of illegal aliens. Why work visas are a problem and what Gov. Ron DeSantis (R-Fla.) is doing about it in his state. European nations lining up to recognize a Palestinian state. Who is responsible for the starving happening in Gaza? GDP grows by 3%, but Democrats aren't pleased. Federal Reserve refuses to lower interest rates. Rep. Nancy Pelosi (D-Calif.) doesn't like questions about her stock market triumphs while the Congress looks to ban what made her rich. Senator Chuck Grassley (R-Iowa) is upset with President Trump. Dunkin' Donuts ad joins American Eagle. Fort Hood is back to being Fort Hood. Genetic testing for female athletes in women's sports. Kathy Hochul blames guns, while Zohran Mamdani doubles down on his disgust for police. Why won't Curtis Sliwa join "Pat Gray Unleashed"? 00:00 Pat Gray UNLEASHED! 01:01 Trump Explains Why He's Using Tariffs 02:21 Trump Explains Deal with EU 02:56 Trump Makes Deal with South Korea 04:22 Trump on Deportation of Illegals 05:31 New DHS Ad 08:34 Another Sob Story of a Criminal Illegal 18:24 Ron DeSantis on Work Visas 24:37 Keir Starmer on Recognizing a Palestinian State 31:33 Why is Gaza Starving? 35:22 Cincinnati Beatdown Update 36:47 GDP is 3% 37:39 Chuck Schumer on the 'Mirage' GDP Growth 42:57 Jerome Powell on Interest Rate Cut 49:14 Trump Wants Nancy Pelosi Investigated 51:30 Jake Tapper Confronts Nancy Pelosi's Insider Trading 58:14 Chuck Grassley is Sad 1:09:27 "Controversial" Dunkin' Donuts Ad 1:12:09 Fort Hood Gets its Name Back 1:15:49 Major Win for Biologically Female Athletes 1:26:10 Kathy Hochul Blames Assault Weapons for NYC Shooting 1:30:39 Zohran Mamdani Wants to Ban Assault Rifles 1:32:12 Zohran Mamdani on Defunding the Police Learn more about your ad choices. Visit megaphone.fm/adchoices
Saturated fat -- not eggs -- is the key culprit behind high LDL cholesterol, which can lead to cardiovascular disease And in fact, a diet low in saturated fat and high in dietary cholesterol, such as that found in eggs, can lower blood cholesterol levels. This -- according to a new study from researchers at the University of South Australia. But what are we to make of this study, which received funding from an offshoot of the American Egg Board, an organization focused on marketing and promoting eggs? Dr. Neal Barnard joins Chuck Carroll on this episode of The Exam Room to tell us what he makes of these findings, and to answer your questions about saturated fats, dietary cholesterol and eggs. In this episode of The Exam Room, you'll learn: - Whether eggs raise cholesterol for everyone - Whether eggs egg whites and free-range eggs are healthier options - Dr. Barnard's favorite egg substitutes - Whether eggs or meat and dairy have a greater impact on cholesterol - How many eggs are safe to eat per week - How saturated fat influences cholesterol absorption - How quickly eggs can raise cholesterol - Genetic factors that influence cholesterol This episode is sponsored by The Gregory J. Reiter Memorial Fund, which supports organizations like the Physicians Committee that carry on Greg's passion and love for animals through rescue efforts, veganism, and wildlife conservation. — — SHOW LINKS — — Gregory J. Reiter Memorial Fund https://gregoryreiterfund.org — — — Shelfy Refrigerator Purifier https://vitesy.com/shelfy — — — Egg Cholesterol Study https://bit.ly/eggstudy2025 — — EVENTS — — International Conference on Nutrition in Medicine Where: Washington, DC When: August 14-16, 2025 Tix & Speakers: https://www.pcrm.org/icnm Use code NUTRITION50 to save $50 — — — Fit Vegan Workshop Where: Vancouver, BC, Canada When: Sept. 20-21, 2025 Tix: https://fitvegancoaching.com/vancouver-2025 Use code CHUCK to save $112 — — — Wellness Weekend Where: Canaan Valley Resort - Davis, WV When: Sept. 26-27, 2025 Tix & Speakers: https://www.brendaworkmanspeaks.com/wellness-weekend — —EXAM ROOM — — Newsletter: https://www.pcrm.org/examroomvip Instagram: https://www.instagram.com/theexamroompodcast — — — Dr. Neal Barnard Books: https://amzn.to/3HhVlrF Instagram: https://www.instagram.com/drnealbarnard Facebook: https://www.facebook.com/NealBarnardMD X: https://x.com/DrNealBarnard — — — Chuck Carroll Instagram: https://www.instagram.com/ChuckCarrollWLC Facebook: https://www.facebook.com/ChuckCarrollWLC X: https://www.twitter.com/ChuckCarrollWLC — — — Physicians Committee Instagram: https://www.instagram.com/physicianscommittee Facebook: https://www.facebook.com/PCRM.org X: https://www.twitter.com/pcrm YouTube: https://www.youtube.com/user/PCRM Jobs: https://www.pcrm.org/careers — — SUBSCRIBE & SHARE — — 5-Star Success: Share Your Story Apple: https://apple.co/2JXBkpy Spotify: https://spoti.fi/2pMLoY3 — — — Please subscribe and give the show a 5-star rating on Apple Podcasts, Spotify, or many other podcast providers. Don't forget to share it with a friend for inspiration!