Podcasts about Genetic

Medical oncologist, geriatrician, and physician scientist GJ van Londen and Chief of Genetic and Genomic Medicine at the University of Pittsburgh School of Medicine Gerald Vockley discuss the article "FDA delays could end vital treatment for rare disease patients." GJ and Gerald explore the complex regulatory impasse where the U.S. Food and Drug Administration denied standard approval for elamipretide despite a positive advisory committee vote, creating a financial crisis that threatens to cut off supply for everyone. GJ shares his personal journey from treating cancer to living with primary mitochondrial myopathy, while the conversation emphasizes the critical need for the agency to use the flexibility granted by the Orphan Drug Act to save a treatment that has already proven its worth. Join us to understand the life-or-death stakes hidden behind administrative decisions. This episode is presented by Scholar Advising, a fee-only financial advising firm specializing in providing advice for DIY investors. If you want clear, actionable strategies and confidence that your financial decisions are built on objective advice without AUM fees or commissions, Scholar is designed for you. Physicians often navigate complex compensation structures, including W-2 income, 1099 work, production bonuses, and practice ownership. Scholar's highly credentialed advisors guide high-earners through decisions like optimizing investments for long-term tax efficiency and expert strategies for financial independence. Every recommendation is tailored to the financial realities physicians face. VISIT SPONSOR → https://scholaradvising.com/kevinmd SUBSCRIBE TO THE PODCAST → https://www.kevinmd.com/podcast RECOMMENDED BY KEVINMD → https://www.kevinmd.com/recommended

The Tenpenny Files – Newborn screening is quietly crossing a genetic threshold. As whole-genome sequencing enters hospitals and public health systems, DNA collected at birth begins shaping medical pathways long before symptoms appear. I examine how these programs expand, how data is stored and shared, and what this shift means for parental authority and lifelong medical autonomy...

Text Dr. Lenz any feedback or questions Understanding the Link Between ADHD and Trauma with Dr. Iris ManorJoin us as we explore the intricate connections between ADHD, PTSD, and trauma with Dr. Iris Manor, a renowned child and adolescent psychiatrist and director of the lifespan ADHD clinic at Gaha Mental Health Clinic. In this in-depth discussion, Dr. Manor sheds light on why individuals with ADHD are more prone to developing traumatic stress disorders and PTSD, backed by research and case studies. We delve into the biological, behavioral, and environmental factors contributing to these conditions, as well as the essential treatment and management strategies. Dr. Manor also emphasizes the importance of treating ADHD to mitigate the impact of trauma and provides valuable insights into the role of family dynamics in recovery. Whether you're a clinician, a parent, or someone living with ADHD and trauma, this episode offers vital information and practical advice.Watch on YouTube Here00:00 Introduction to the Podcast and Special Guest01:19 Understanding the Link Between ADHD and Trauma03:20 Behavioral and Biological Explanations05:22 Genetic and Environmental Factors07:53 Impact of Trauma on ADHD14:16 COVID-19 as a Trauma and Its Effects19:23 Treatment and Resilience Strategies26:05 Positive Magic Circle for PTSD and ADHD26:31 Screening Parents for ADHD and PTSD26:49 Diagnosing and Treating Families29:22 Challenges in Treating ADHD and PTSD31:36 Emotional Dysregulation and ADHD33:48 Medications for Emotional Dysregulation36:23 Autism, ADHD, and Trauma39:07 The Impact of Trauma on ADHD44:48 ADHD Awareness and Treatment Click here for the YouTube channel International Conference on ADHD in November 2025 where Dr. Lenz will be one of the speakers. Joy LenzFibromyalgia 101. A list of fibromyalgia podcast episodes that are great if you are new and don't know where to start. Support the showWhen I started this podcast and YouTube Channel—and the book that came before it—I had my patients in mind. Office visits are short, but understanding complex, often misunderstood conditions like fibromyalgia takes time. That's why I created this space: to offer education, validation, and hope. If you've been told fibromyalgia “isn't real” or that it's “all in your head,” know this—I see you. I believe you. This podcast aims to affirm your experience and explain the science behind it. Whether you live with fibromyalgia, care for someone who does, or are a healthcare professional looking to better support patients, you'll find trusted, evidence-based insights here, drawn from my 29+ years as an MD. Please remember to talk with your doctor about your symptoms and care. This content doesn't replace per...

If your kid sneezes the way your do, is it genetic?

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Dr. Stephanie goes "holiday-solo" for the third and final time this week to discuss the growing claim that obesity is mainly genetic, with diet and exercise only accounting for 15% of results. She explains why this messaging is scientifically questionable and potentially harmful, especially for women in perimenopause and menopause who feel powerless. In this candid solo episode, Dr. Stephanie addresses the recent trend of medical professionals suggesting that GLP-1 medications like Ozempic are more effective than lifestyle interventions, and why this approach undermines women's agency. She acknowledges genetic predispositions but argues that resistance training and protein-forward nutrition should remain our primary tools for metabolic health.Episode overview:(0:00) Intro/Teaser(2:00) The Instagram Post(4:00) The Role of Neurochemicals in Obesity(5:00) Glucose Metabolism and Muscle Quality(6:00) Hormonal Changes in Midlife(7:00) Critique of Genetic Determinism in Obesity(12:00) The Importance of Diet and Exercise(19:00) Teaching Healthy Habits to Children(21:00) Final Thoughts and Action StepsResources mentioned in this episode can be found at https://drstephanieestima.com/podcasts/ep450/We couldn't do it without our sponsors:PIQUE - Designed to deeply hydrate, enhance skin elasticity & firmness and support sustained energy—exactly what we need during this stage of life. Start your daily ritual today with 20% off for life—plus a free gift to elevate your routine. Head to https://piquelife.com/drestima.TROSCRIPTIONS - There's a completely new way to optimize your health. Give it a try at https://troscriptions.com/BETTER or enter BETTER at checkout for 10% off your first order.JUST THRIVE HEALTH - Take the Just Thrive FEEL BETTER challenge today, and save 20% on your first order. Go to https://justthrivehealth.com/better and use the code BETTER to see the difference for yourself or get a full product refund, no questions asked.AGZ - If you're ready to turn down the stress and focus on the rest, head to https://drinkag1.com/STEPHANIE to get a FREE Frother with your first purchase of AGZ.LVLUP - Ultimate GI Repair combines powerful gut-healing peptides with gut-nourishing naturals to soothe your changing digestion. Go to https://lvluphealth.com/DRSTEPHANIE and use code DRSTEPHANIE for 15% off. P.S. When you're ready, here are a two ways I can help you:Subscribe: The Mini Pause — My weekly newsletter packed with the most actionable, evidence-based tools for women 40+ to thrive in midlife.Build Muscle: LIFT — My progressive strength training program designed for women in midlife. Form-focused, joint-friendly, and built for real results. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In this episode, Dr. Theodore Schurr shares insights from his career researching genetic prehistories, linkages, and identities within transforming geopolitical landscapes of the past as well as contemporary sociopolitical shifts, including post-Soviet Russia and Georgia. Next, Dr. Schurr and hosts Cara and Chris reflect on the evolution of anthropology and genetic research, including breakthrough technologies and advanced field methods, changing bioethics, intentional relationships with communities, and exciting new approaches that are expanding our understanding of variation and genetic-environmental interactions of the past and present. Dr. Theodore (Tad) Schurr is a Professor in the Department of Anthropology and the Director of the Laboratory of Molecular Anthropology at the University of Pennsylvania. For over thirty years, he has investigated the genetic prehistory of Asia and the Americas through studies of mtDNA, Y-chromosome, and autosomal DNA variation in Asian, Siberian, and Native American populations. For these studies, his lab characterized genetic diversity in indigenous populations of Canada, the United States, Mexico, and the Caribbean. His research group is currently exploring the population history of Georgia (Caucasus), Pakistan, Kazakhstan, and Polynesia through collaborative studies in those regions. Other projects have investigated the role of the mtDNA in adaptation, cancer, complex diseases, and metabolism. ------------------------------ Find the papers discussed in this episode: Yardumian, A., Shengelia, R., Chitanava, D., Laliashvili, S., Bitadze, L., Laliashvili, I., ... & Schurr, T. G. (2017). Genetic diversity in Svaneti and its implications for the human settlement of the Highland Caucasus. American journal of physical anthropology, 164(4), 837-852. Schurr, T. G., Shengelia, R., Shamoon-Pour, M., Chitanava, D., Laliashvili, S., Laliashvili, I., ... & Yardumian, A. (2023). Genetic analysis of Mingrelians reveals long-term continuity of populations in Western Georgia (Caucasus). Genome Biology and Evolution, 15(11), evad198. Ancient Lineages: Reconstructing the Genetic History of Svaneti, Northwest Georgia https://www.penn.museum/sites/expedition/ancient-lineages/ ------------------------------ Contact Dr. Schurr: tgschurr@sas.upenn.edu ------------------------------ Contact the Sausage of Science Podcast and the Human Biology Association: Facebook: facebook.com/groups/humanbiologyassociation/, Website: humbio.org, Twitter: @HumBioAssoc Chris Lynn, Co-Host Website: cdlynn.people.ua.edu/, E-mail: cdlynn@ua.edu, Twitter:@Chris_Ly Cara Ocobock, Co-Host Website: sites.nd.edu/cara-ocobock/, Email:cocobock@nd.edu, Twitter:@CaraOcobock Mecca Howe, SoS Co-Producer, HBA Fellow LinkedIn: https://www.linkedin.com/in/mecca-howe/, Email: howemecca@gmail.com

Think a great wine grape can't survive where winters drop to minus forty? We sit down with breeder Dr. Harlene Hatterman-Valenti from North Dakota State University to unpack how a young industry, a focused research program, and some stubborn optimism produced two new cultivars built for the northern plains. From the early days of variety trials and policy hurdles to the release of Dakota Primus and Radiant, Harlene shares how hybrid genetics, gritty selection, and clever management turned a hostile climate into an advantage.We dig into the science of cold hardiness: why photoperiod sensitivity matters more than you think, how vines must read shortening days to lay down periderm before sudden freezes, and the three critical windows where cold injury strikes—fall acclimation, deep midwinter lows, and late-winter temperature whiplash. Harlene explains the growth calendar for a North Dakota vineyard with just 130 frost-free days, from delayed pruning and cautious budbreak to early-August veraison and mid-September harvests. Beyond the vineyard, we explore how the state's wine scene found its footing, why regulations evolved to support consistent supply, and how tourism now fuels growth. The conversation closes with what's next: chasing an ultra-cold-hardy red, expanding into table grapes for farmers markets, and celebrating the team effort—students, specialists, and collaborators—that made progress possible. If you're curious about cold-climate viticulture, breeding under polar vortex pressure, or how science builds regional wine identities, this one's for you.Additional information in available in these articles:Complex Plant Process Trait Evaluation Through Decomposition of Higher-order Interaction: A Case Study in Acclimation Responses of Cold-climate Hybrid Grapevine Through Bilinear and Multiway MethodsCold Climate Winegrape Cultivar Sensitivity to Sulfur in the Northern Great Plains Region of the United States‘NDMutant1': A Novel Determinate Interspecific Grapevine for Genetic and Physiological Study and Breeding ApplicationsEnjoyed the conversation? Follow the show, share it with a friend, and leave a review to help more growers and wine lovers find us.Learn more about the American Society for Horticultural Science (ASHS) at https://ashs.org/.HortTechnology, HortScience and the Journal of the American Society for Horticultural Science are all open-access and peer-reviewed journals, published by the American Society of Horticultural Science (ASHS). Find them at journals.ashs.org.Consider becoming an ASHS member at https://ashs.org/page/Becomeamember!You can also find the official webpage for Plants, People, Science at ashs.org/plantspeoplesciencepodcast, and we encourage you to send us feedback or suggestions at https://ashs.org/webinarpodcastsuggestion. Podcast transcripts are available at https://plantspeoplescience.buzzsprout.com.On LinkedIn find Sam Humphrey at linkedin.com/in/samson-humphrey. Curt Rom is at https://www.linkedin.com/in/curt-rom-611085134/. Lena Wilson is at https://www.linkedin.com/in/lena-wilson-2531a5141/. Thank you for listening! ...

In Episode 1, I revealed the clues hidden in my labs — the WHY behind my fatigue, slower recovery, reduced power output, dry skin, and metabolic slowdown. Now in Part 3 & Part 4 of my personal case study, we turn insight into ACTION. You'll learn: The ROOT-CAUSE MAP of my body • Low ATP from microbiome imbalance • Fat malabsorption choking metabolism • LPS/endotoxin stress suppressing fat burning • High cortisol blocking thyroid activation • Oxidative stress damaging mitochondria • Genetic vulnerabilities amplifying the effect How this showed up in real life • Running performance dropping • Heart rate spikes in Zone 2 • Needing more fuel on long efforts • Harder time building + maintaining muscle • Skin + hormone changes • Mood and motivation shifts The 4-Phase FutureYou Blueprint™ Plan I built for myself PHASE 1 — Digest • Absorb • Drain PHASE 2 — Kill • Clear • Rebuild PHASE 3 — Mitochondria + Muscle Reboot PHASE 4 — Longevity Optimization I walk you through the WHY behind every tool, including: • TUDCA • Tributyrin (butyrate) • S. boulardii • Phosphatidylcholine • Creatine, CoQ10, PQQ, DHA • Nervous system support • HBOT, sauna, cold exposure This is exactly how I help clients transform from burned-out and metabolically stuck → to energized, strong, and aging powerfully. If you're ready to create your own FutureYou Blueprint™, this episode will show you what's possible when you finally stop guessing — and start investigating.

Episode 2744 - Vinnie Tortorich welcomes back Dr. Anthony Chaffee, and they discuss animal-based diet and developmental matters in humans. https://vinnietortorich.com/2026/01/developmental-matters-dr-anthony-chaffee-episode-2744 PLEASE SUPPORT OUR SPONSORS Pure Vitamin Club Pure Coffee Club NSNG® Foods VILLA CAPPELLI EAT HAPPY KITCHEN YOU CAN WATCH THIS EPISODE ON YOUTUBE - @FitnessConfidential Podcast Developmental Matters But first: Vinnie's NSNG® VIP Group opens up today! Vinnie's workout videos, group calls, and supportive community are waiting for you, FREE to all members who join! Dr. Chaffee explains his medical credentials. (2:00) His low-carb approach with his patients has helped people dramatically improve their health, including putting autoimmune disease into remission. (8:00) Lack of specific vitamins has been shown to reduce brain size. (11:00) They discuss the benefits of liver and whether dessicated liver supplements are worth the expense. (19:00) The goal is to get enough methylated B-12. (22:00) Genetic factors and environmental triggers are in an exposure relationship. (26:00) Dr. Chaffee discusses developmental matters, including how the evolution of our brains and bodies has been affected over the years. (33:00) Eating meat has been demonstrated to help form the jaw and dental structures. (42:00) They discuss the documentary The Magic Pill, which follows the beneficial effects of a ketogenic diet. (45:30) The documentary reviews how a modernized, processed diet has affected some indigenous peoples. There was a trend when Vinnie was young: an all-protein diet. (57:00) Dr. Chaffee explains what can happen in your body from an all-protein diet. Be aware: a properly structured carnivore or ketogenic diet is not an issue. (59:00) They discuss people hitting a plateau in their weight loss. (1:01:00) You can find Dr. Anthony Chaffee at https://dranthonychaffee.com A New Sponsor Jaspr Air Scrubbers has a discount code, VINNIE, that gets you $400 off for a limited time. Jaspr offers a lifetime warranty. Go to Jaspr.co for more information or to purchase. Don't forget to sign up for the NSNG VIP group. Vinnie's video workouts will be free to all members! (1:05:00) You can get on the wait list -https://vinnietortorich.com/vip/ Also, you'll want to join as soon as it opens, because once it closes again, it will be closed indefinitely. You can book a consultation with Vinnie to get guidance on your goals. https://vinnietortorich.com/phone-consultation-2/ More News Serena has added some of her clothing suggestions and beauty product suggestions to Vinnie's Amazon Recommended Products link. Self Care, Beauty, and Grooming Products that Actually Work! Don't forget to check out Serena Scott Thomas on Days of Our Lives on the Peacock channel. "Dirty Keto" is available on Amazon! You can purchase or rent it here.https://amzn.to/4d9agj1 Please make sure to watch, rate, and review it! Eat Happy Italian, Anna's next cookbook, is available! You can go to https://eathappyitalian.com You can order it from Vinnie's Book Club. https://amzn.to/3ucIXm Anna's recipes are in her cookbooks, website, and Substack — they will spice up your day! https://annavocino.substack.com/ Don't forget you can invest in Anna's Eat Happy Kitchen through StartEngine. Details are at Eat Happy Kitchen. https://eathappykitchen.com/ PURCHASE DIRTY KETO (2024) The documentary launched in August 2024! Order it TODAY! This is Vinnie's fourth documentary in just over five years. Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries Then, please share my fact-based, health-focused documentary series with your friends and family. Additionally, the more views it receives, the better it ranks, so please watch it again with a new friend! REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! PURCHASE BEYOND IMPOSSIBLE (2022) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! FAT: A DOCUMENTARY 2 (2021) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries FAT: A DOCUMENTARY (2019) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries

In this episode of the Gladden Longevity Podcast, Dr. Jeffrey Gladden interviews Chloe Harrouche, who shares her transformative journey through a breast cancer diagnosis at a young age. Chloe discusses her initial admiration for the healthcare system, which shifted dramatically after her diagnosis. She explores the challenges of navigating post-treatment care, the limitations of traditional oncology, and her eventual turn to functional medicine. The conversation delves into the importance of understanding the nervous system's role in health, the societal pressures of stress, and the need for a more integrated approach to wellness in primary care. In this conversation, Chloe Harrouche discusses the need for a new model of healthcare that emphasizes health optimization, personalized wellness, and a membership-based approach to primary care. She highlights the challenges of the current healthcare system, including the siloing of care and the overwhelming amount of data available to consumers. The discussion also touches on the importance of genetic testing and the vision for the future of healthcare, including expanding services to pediatrics and democratizing access to care.     For Audience ·       Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/ !    Takeaways ·        Chloe's journey in healthcare began with a passion for bioengineering. ·        Her breast cancer diagnosis at 23 changed her perspective on healthcare. ·        Post-treatment, she found traditional oncology lacking in preventive care. ·        Chloe explored functional medicine to address her health concerns. ·        The importance of balancing wellness interventions with personal health needs. ·        Stress management is crucial for overall health and wellness. ·        The nervous system plays a significant role in health optimization. ·        Many people are unaware of how to shift from stress to calm. ·        Integrating wellness into primary care is essential for patient care. ·        Chloe advocates for a more personalized approach to health.  Health optimization is essential to prevent chronic diseases. ·        Personalized care is missing in the current wellness industry. ·        Data without clinical oversight can overwhelm consumers. ·        A membership model can provide holistic support for patients. ·        Coordination of care is crucial for effective health management. ·        The insurance model incentivizes volume over quality of care. ·        Genetic testing can inform proactive health decisions. ·        The goal is to empower patients to take charge of their health. ·        Future plans include expanding services to pediatrics. ·        Transparency in healthcare pricing is vital for trust.       Chapters 00:00 Introduction to Chloe Harrouche's Journey 01:04 The Impact of a Breast Cancer Diagnosis 06:01 Navigating Post-Treatment Healthcare 10:57 Exploring Functional Medicine 15:40 The Role of the Nervous System in Health 20:59 The Challenge of Stress and Wellness 24:14 Integrating Wellness into Primary Care 24:39 The Need for Health Optimization 28:06 Reimagining Primary Care 30:31 The Membership Model of Care 33:10 Navigating Challenges in Healthcare 37:50 Vision for the Future of Healthcare 40:21 Empowering Through Genetic Testing   To learn more about Chloe Harrouche: Email:  chloe@thelanby.com Website: https://www.thelanby.com/   Reach out to us at:    Website: https://gladdenlongevity.com/     Facebook: https://www.facebook.com/Gladdenlongevity/    Instagram: https://www.instagram.com/gladdenlongevity/?hl=en     LinkedIn: https://www.linkedin.com/company/gladdenlongevity    YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw       Gladden Longevity Podcast Disclosures Production & Independence The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas. Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements. Medical Disclaimer The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content. The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options. Use of information from this podcast and any linked materials is at the listener's own risk. Podcast Guest Disclosures Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team. Sponsorships & Affiliate Disclosures To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes. We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented. Additional Note on Content Integrity All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.

Are you training hard, eating clean, and doing "all the right things"… but your body still isn't responding the way it used to? That was me. Even as a lifelong athlete and Functional Diagnostic Nutrition Practitioner — I hit a wall. My power dipped. My runs felt harder. My skin changed. Fat loss stalled. Recovery lagged. Something wasn't adding up. So I became my own case study. In this two-part deep-dive series, I take you behind the scenes of my personal health investigation — the exact process I use with clients to build their FutureYou Blueprint™ using: • GI MAP gut microbiome testing • Advanced blood chemistry analysis • Mescreen™ mitochondrial function testing • Genetic stress + metabolism vulnerability profiling • My symptom timeline and history In Part 1 & Part 2, you'll learn:

Dr. Peter McCullough walks through what he's seeing clinically — patients years out from COVID or vaccination who are still dealing with clotting issues, neurologic symptoms, immune dysregulation, mast cell activation, and unexplained decline. Not rare cases. Everyday people. Many of them functional — until they weren't.We talk about why Long COVID isn't always a new condition, but often the thing that pushes underlying vulnerabilities into the open. Genetic predispositions. Autoimmune tendencies. Histamine intolerance. Microvascular injury. Things that were once quiet suddenly aren't.May shares her own experience from the patient side — navigating worsening symptoms, being told it was hormones, stress, or anxiety, and eventually realizing the timeline didn't lie. The labs didn't either.Dr. McCullough explains why antibody levels matter, why spike protein itself is rarely measured, and why chasing secondary diagnoses (Lyme, mold, EBV, heavy metals) often leads people in circles without addressing the root issue.This isn't a protocol episode.It's not reassurance.And it's not abstract.It's a direct conversation about ongoing biological injury, what's being missed, and why so many people feel like their bodies changed — and never fully came back.If you've felt stuck in that in-between space — not sick enough for answers, not well enough to live normally — this episode speaks to exactly that gap.Guest Bio: Dr. Peter McCulloughDr. Peter McCullough is a practicing cardiologist, internist, and clinical researcher with decades of experience in cardiovascular medicine and academic publishing. He has served on the faculties of multiple medical schools, contributed to hundreds of peer-reviewed publications, and has been deeply involved in clinical research, outcomes analysis, and patient care throughout his career.Since the COVID era began, Dr. McCullough has focused extensively on understanding post-infection and post-vaccination complications, including myocarditis, thrombosis, immune dysregulation, and Long COVID–related syndromes. He continues to treat patients clinically while examining emerging data on persistent spike protein, inflammatory injury, and recovery patterns that fall outside traditional medical frameworks.Known for his willingness to question prevailing narratives and follow the data where it leads, Dr. McCullough remains a polarizing but influential voice in ongoing discussions about public health, patient safety, and the long-term consequences of pandemic-era medical decisions.Join this important mission: www.mcculloughfnd.org GET SOCIAL WITH US!

Send us some Fan Mail? Yes please!These two never stop, do they? Not to mention, they don't even cover the most obvious Scuttlebutt bobbing around right now. Instead, they talk about Somalia fraud videos, Nick Fuentes, Navy physical training requirements, and even MSNBC hosting hot takes; nothing about the holidays or New Year plans. Another swing and a miss for these two (if you ask us).Subscribe, rate us 5, come join in all the other fun we offer, but most of all we hope you enjoy! If you liked this, and want to hear more, give us a follow and let us know! Or maybe you just want to tell us how awful we are? Comments help the algorithm, and we love to see ‘em! And as always, don't kill the messenger. Whiskey Fund (help support our podcast habit!): PayPalOur Patreon & YouTube Connect with Hermes: Instagram & Twitter Connect with Khaleesi: Instagram & Twitter Support the show

In today's webinar, Tom did a follow-up to the avian bird flu/ostrich story and also did a discussion on a specific so called "genetic" disease - and going into detail on whether they really are "genetic"Support the showWebsites:https://drtomcowan.com/https://www.drcowansgarden.com/https://newbiologyclinic.com/https://newbiologycurriculum.com/Instagram: @TalkinTurkeywithTomFacebook: https://www.facebook.com/DrTomCowan/Bitchute: https://www.bitchute.com/channel/CivTSuEjw6Qp/YouTube: https://www.youtube.com/channel/UCzxdc2o0Q_XZIPwo07XCrNg

One on One Video Call W/George https://tidycal.com/georgepmonty/60-minute-meetingSupport the show:https://www.paypal.me/Truelifepodcast?locale.x=en_US

In this episode, we explore the relationship between nutrition and genetic potential in gamefowl and chickens. While genetics play a foundational role in a bird's growth and development, egg production, immunity, and overall performance, it's optimal nutrition that truly allows these genetic traits to shine. Each stage of a bird's life requires specific nutrients to ensure they reach their maximum potential. We'll dive into the importance of proteins, essential amino acids, vitamins, and minerals—understanding how these nutrients influence growth, development, feather quality, immunity, egg production, performance ability, and reproductive health. We'll discuss how deficiencies in protein, calcium, vitamins, and energy can stunt growth, weaken immune systems, and reduce reproductive success, ultimately hindering the chicken's ability to perform at its genetic best. Knowing what your birds need at each life stage—from chicks to adults—is key to unlocking their full potential. Join us for insights on how proper nutrition can enhance the performance of your bloodline and strain, maximize growth and development, boost production, improve performance, and ensure strong, healthy bird's throughout their lives. This episode is a must-listen for anyone involved in breeding gamefowl and chickens, or anyone looking to better understand the role of nutrition in their strains. #PoultryNutrition #GamefowlNutrition #ChickenNutrition #GeneticsAndNutrition #GamefowlBreeding #ChickenBreeding #BloodlineDevelopment #PoultryHealth #ProteinForGrowth #VitaminsAndMinerals #PoultryImmunity #FeatherQuality #EggProduction #ReproductiveHealth #GrowthAndDevelopment #PerformanceNutrition #HealthyFlock #PoultryScience See ya there! Kenny Troiano Founder of "The Breeders Academy"  We specialize in breeding, and breeding related topics. This includes proper selection practices and the use of proven breeding programs. It is our mission to provide our followers and members a greater understanding of poultry breeding, poultry genetics, poultry health care and disease prevention, and how to improve the production and performance ability of your fowl.  If you are interested in creating a strain, or improving your established strain, you are in the right place.  We also want to encourage you to join us at the Breeders Academy, where we will not only help you increase your knowledge of breeding and advance your skills as a breeder, but improve the quality and performance of your fowl. If you would like to learn more, go to: https://www.breedersacademy.com

This is the Season 3 finale.I'm wrapping up the year and reflecting on what we covered this season, including the Mineral Series, thyroid deep dives, and guests like Dr. Carolyn Dean, Kim Rodgers, and Amber White.I also share what's ahead for season 4, including Michael Biamonte coming on to talk about Candida research and my own deep dive into mold toxicity - what I tested, what didn't work, and what actually helped.If you've been wanting to do The Genetic Detox Protocol, enrollment closes January 5th. I also share what happened when I got my own detox genetics read - and why it explained so much about why my mold detox was taking forever. If you've ever felt like you're doing everything right but still stuck, this might land.In this episode:Season 3 Recap and Favorite MomentsWhat's coming in Season 4The Genetic Detox ProtocolLAST CHANCE for the Genetics Detox Package. Offer lasts until January 5th, 2026.Learn more here: https://detox.shetalkshealth.com/

Ferg shares his thoughts on genetic gain in the sheep and beef industries. He has often said that we should be seeking to achieve a minimum of 2% genetic gain, but the top operators we deal with here at neXtgen Agri are consistently achieving 3-4%. Ferg explains how they've achieved that with the use of selection accuracy and the compounding effect of disciplined breeding decisions over time.Ferg also talks about what that genetic gain actually means for each farm and what traits we should be looking at to optimise performance. Some traits benefit all farms, no matter the location (things like worms, dags and feet), and others that are more system-specific.  Head Shepherd is brought to you by neXtgen Agri International Limited. We help livestock farmers get the most out of the genetics they farm with. Get in touch with us if you would like to hear more about how we can help you do what you do best: info@nextgenagri.com.Thanks to our sponsors at MSD Animal Health and Allflex, and Heiniger Australia and New Zealand. Please consider them when making product choices, as they are instrumental in enabling us to bring you this podcast each week.Check out Heiniger's product range HERECheck out the MSD range HERECheck out Allflex products HERE

Cancer, cardiovascular disease, diabetes, mold toxicity, parasites, and chronic illness are often treated as separate problems—but what if they all stem from the same root cause? David DeHaas, founder of Living Waters Wellness Center, sits down with Alicia Hickson, PA-C, founder of Rama Health, to explore why cancer is not primarily a genetic disease, but a metabolic and mitochondrial disorder driven by inflammation, toxins, mold exposure, parasites, blood sugar dysregulation, emotional trauma, and impaired detoxification pathways.Drawing from the groundbreaking research of Dr. Thomas Seyfried, Alicia explains how damaged mitochondria alter cellular energy production, creating an internal environment where cancer and chronic disease can thrive. This conversation challenges the conventional genetic theory of cancer and reframes healing through the lens of terrain medicine.Throughout the episode, David and Alicia connect the dots between:Mitochondrial dysfunction and cancer metabolismMold toxicity, candida, yeast, and immune system overloadParasites and chronic inflammationEmotional trauma, unforgiveness, and limbic system dysregulationConstipation, lymphatic congestion, and impaired detox pathwaysWhy genetics account for only a small percentage of disease riskWhy conventional medicine often misses root causesWhen integrative and conventional medicine work best togetherDavid shares compelling real-world cases from Living Waters Wellness Center, including parasite cleansing, colon hydrotherapy, emotional release, and rapid shifts in tumor presentation—demonstrating how healing accelerates when the body's internal terrain is restored.Alicia also breaks down advanced clinical tools and therapies, including:Circulating tumor cell testing for cancer monitoringHormone metabolism and estrogen detox pathways (DUTCH testing)Mold and mycotoxin testing strategiesHyperthermia therapy, mistletoe therapy, and immune modulationWhy maintaining remission is just as important as treating cancerThis episode is essential listening for anyone who has been told, “There's nothing more we can do,” aSupport the show Ready for your healing journey?Visit our website: www.LivingWatersCleanse.com Or give us a call at: (208) 378-9911Stem Cell Activation Patches:www.StemCellPatch.netGet your Supplements and Natural Body Products Here:www.livingwaterscleanse.com/supplementsQI-Shield EMF Devices:Protect your whole home or office with a touric shield from EMF's. 1. QI Shield Covers 16'x16' 2. QI Home Covers 50' x 50' 3. QI Max Covers 250'x250'Click on link and enter Livingwaters in discount code section during checkout Magnesium Soaks:Follow us on our socials: Living Waters Wellness CenterBitChute: www.bitchute.com/livingwaterswellnessRumble: www.rumble.com/l...

Jody Allair, Martha Harbison, and Rebecca Heisman join host Nate Swick for the last American Birding Podcast episode of the year, with a wide-ranging discussion of some of the latest bird and birding news. The panel talks warbler hybrids, vacant lots, and how to best yell at gulls among other things! Thanks for a great year! Also, don't forget to join the ABA for our 2026 Bird of the Year reveal on January 5, 2026, at 4 PM ET.  Links to articles discussed in this episode: Look at those nasty and lovely birds! Assessing preferences and emotional responses of visitors to a National Park The role of vacant lots in promoting avian species diversity and occupancy in a post-industrial city Genetic confirmation of an "uncommon mourningthroat" (Geothlypis philadelphia  ×  G. trichas): A rare but persistent hybrid warbler Want gulls to back off? Here's how to talk to them Subscribe to the podcast at Apple Podcasts, Spotify, or wherever you get your podcasts and please leave a rating or a review if you are so inclined! We appreciate it!  

Wednesday 24 December 2025 To hear the fascinating FULL discussion, become a MEMBER today and enjoy this and other full featured content. “Reconquest” is a militant, engaging, and informative Catholic radio program featuring interviews with interesting guests as well as commentary by your host. It is a radio-journalistic extension of the Crusade of Saint Benedict Center.

Do you know how to recognize ATTR earlier, navigate complex diagnostics, and apply the latest therapeutic innovations?   Credit available for this activity expires: 12/23/2026 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/real-time-insights-diagnosis-and-management-attr-genetic-2025a1000yeo?ecd=bdc_podcast_libsyn_mscpedu

In this episode of the MaternalRX podcast on the Pharmacy Podcast Network, Danielle sits down with Dr. Tadeh Vartanian, a Pharmacist and Medical Lead with deep expertise in autoimmune diabetes. Drawing on years of clinical practice and research, Dr. Vartanian explains why early detection and precise diabetes classification can dramatically shift outcomes for people who are pregnant, planning pregnancy, or managing complex metabolic risks. This conversation delivers a practical, up-to-date overview of diabetes types, maternal risk considerations, screening strategies, and the emerging science behind autoimmune and genetic diabetes. And if you have never heard of monogenic diabetes, you will want to hear this episode! Understanding this category can immediately change how clinicians diagnose and treat patients. Diabetes types explained - How to differentiate type 1 diabetes, type 2 diabetes, gestational diabetes, and monogenic diabetes - Why type 1 is autoimmune and what loss of 80 to 90 percent of beta cells means for patient management - The phases of type 1 diabetes and the predictive power of autoantibodies - How monogenic diabetes presents differently and when to consider genetic testing - Which diabetes types can improve with targeted lifestyle interventions Diabetes screening and diagnostic testing - Why early screening is the most impactful action clinicians can take - When to use hemoglobin A1C, fasting glucose, and the oral glucose tolerance test - A clear explanation of the 50-gram and 100-gram Glucola tests used in gestational diabetes screening and diagnosis - How to identify autoimmune diabetes using autoantibody testing Autoantibody screening programs - TrialNet: the NIDDK-supported program offering at-home screening for people with a first-degree relative with type 1 diabetes - ASK (Autoimmunity Screening for Kids): now expanded to adults, with nationwide access through the University of Colorado laboratory - How these programs detect autoimmune diabetes before symptoms develop Genetics, autoimmunity, and diabetes research - How new genetic testing is reshaping the identification of monogenic diabetes - What autoimmune activity means in type 1 diabetes and why early detection matters - Current research, evolving guidelines, and clinical trial insights relevant to maternal health and diabetes care Diabetes and pregnancy - How diabetes influences pregnancy outcomes and why classification accuracy is critical - The long-term significance of gestational diabetes and its link to future type 2 diabetes - Clinical considerations for preconception counseling, prenatal care, and postpartum metabolic health - How maternal diabetes affects the long-term health trajectory of both parent and child Key takeaway from Dr. Vartanian: Screen early and use the right tools. Identifying diabetes risk before symptoms appear can change the course of care at every stage of pregnancy. Connect with our guest and host: - Dr. Tadeh Vartanian: www.linkedin.com/in/tadehvartanian/ - Dr. Danielle Plummer: www.linkedin.com/in/daniellerplummer/

Very near opportunity here! Mr. PD Miller had the chance to sit down and dive into all the lots, and it just doesn't get better. Every lot has something to offer to either the club club or show heifer industries! It's deep, it's diverse, and it sure is fun to listen and learn about what all these females are built on. The sale happens on the 27th on SC Online Sales. Empowerment Is Here. Link

Dilated Cardiomyopathy is the most common cardiomyopathy. We cover causes, including pathophysiology, signs and symptoms, diagnosis and treatment of Dilated Cardiomyopathy. PDFs available here: https://rhesusmedicine.com/pages/cardiologyConsider subscribing (if you found any of the info useful!): https://www.youtube.com/channel/UCRks8wB6vgz0E7buP0L_5RQ?sub_confirmation=1Timestamps:0:00 What is Dilated Cardiomyopathy?0:13 Dilated Cardiomyopathy Epidemiology0:53 Dilated Cardiomyopathy Causes (Primary vs Secondary)1:52 Dilated Cardiomyopathy Pathophysiology (with Compensatory Mechanisms) 4:09 Dilated Cardiomyopathy Signs and Symptoms4:44 Dilated Cardiomyopathy Diagnosis5:49 Dilated Cardiomyopathy TreatmentLINK TO SOCIAL MEDIA: https://www.instagram.com/rhesusmedicine/References:Bice, T.W., 2024. Dilated Cardiomyopathy. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. [online] Available at: https://www.ncbi.nlm.nih.gov/books/NBK441911/. (ncbi.nlm.nih.gov)Genetic and Rare Diseases Information Center (GARD), 2025. Dilated cardiomyopathy. [online] Available at: https://rarediseases.info.nih.gov/diseases/221/dilated-cardiomyopathy.Wikipedia, 2025. Dilated cardiomyopathy. [online] Available at: https://en.wikipedia.org/wiki/Dilated_cardiomyopathy.Life in the Fast Lane (LITFL), 2025. Dilated Cardiomyopathy (DCM) • ECG Library Diagnosis. [online] Available at: https://litfl.com/dilated-cardiomyopathy-dcm-ecg-library/.McDonagh, T.A., 2017. Diagnosis and assessment of dilated cardiomyopathy: a guideline protocol from the British Society of Echocardiography. Echo Research and Practice, 4(3), pp.R85–R98. [online] Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574280/. (pmc.ncbi.nlm.nih.gov)Disclaimer: Please remember this podcast and all content from Rhesus Medicine is for educational and entertainment purposes only and is not a guide to diagnose or to treat any form of condition. The content is not to be used to guide clinical practice and is not medical advice. Please consult a healthcare professional for medical advice.

Morgan & Morgan: If you're ever injured in an accident, you can check out Morgan & Morgan. You can submit a claim in 8 clicks or less without having to leave your couch. To start your claim, visit: https://forthepeople.com/ICED Ekster: Ekster is having a Christmas Sale (from Dec 8 → Dec 26) with up to 54% off. Use code ICED for an extra 10% off on existing offers, getting up to 64% off ! https://partner.ekster.com/ICED Everyday Dose: Get 61% off Coffee+, a free Peppermint Mocha Creamer+, and over $100 in free gifts at https://EverydayDose.com/ICH OR use code ICH at checkout. Add us on Instagram: https://www.instagram.com/jlsselby https://www.instagram.com/gpstephan Apply for The Index Membership: https://entertheindex.com/ Official Clips Channel: https://www.youtube.com/channel/UCeBQ24VfikOriqSdKtomh0w For sponsorships or business inquiries reach out to: tmatsradio@gmail.com For Podcast Inquiries, please DM @icedcoffeehour on Instagram! Timestamps: 00:00:00 - Intro 00:02:11 - Any regrets selling the company? 00:05:31 - Earnings from selling Ancestry 00:06:45 - Why people care about genealogy 00:09:08 - Why tracking ancestry matters 00:11:12 - Identifying personal strengths 00:12:29 - Nature vs nurture beliefs 00:16:29 - Sponsor - Ekster 00:23:19 - Personality tests explained 00:24:30 - Biggest lie about identity 00:26:29 - Most shocking lineage discovery 00:30:42 - Genetic testing at birth 00:32:36 - Taking the company public 00:34:55 - Is there an AI bubble? 00:37:31 - Sponsor - Morgan & Morgan 00:38:30 - Sponsor - Everyday Dose 00:39:56 - Is it easier to start a business today? 00:41:01 - Can anyone become successful? 00:43:03 - Are we too reliant on AI? 00:46:44 - Government's role in AI 00:49:21 - Biggest risk of AI 00:54:49 - Most dramatic AI prediction 01:01:09 - What people misunderstand about AI 01:13:52 - Advice for young entrepreneurs 01:14:43 - Starting over with nothing at 22 01:17:18 - Traits needed for success *Some of the links and other products that appear on this video are from companies which Graham Stephan will earn an affiliate commission or referral bonus. Graham Stephan is part of an affiliate network and receives compensation for sending traffic to partner sites. The content in this video is accurate as of the posting date. Some of the offers mentioned may no longer be available. Learn more about your ad choices. Visit podcastchoices.com/adchoices

We are currently living in an epidemic of a sedentary lifestyle. As we live through our screens whether it be glued to our phones, tablets, or laptops, we tend to miss out on the benefits of movement in our day to day lives - how does movement benefit us?In this episode, Dr. Krista Kostroman, Chief Science Officer of the DNA Company, is joined by Dr. Emily Splichal. She is a functional podiatrist and human movement specialist, is the mind behind Naboso. With a spirit to challenge conformity, Dr. Splichal has taken her conventional Podiatric Medical degree and combined it with years of experience and expertise in human movement and sensory science to found Naboso.Dr. Splichal believes that our experience in this world is built around sensory stimulation and our ability to process, perceive, and integrate this information effectively. Since 2012, Dr. Splichal has been traveling the world to share her unique approach to human movement, foot function, and barefoot science. Having taught in 35 countries and to over 25,000 professionals, Dr. Splichal has quickly become a sought out leader in barefoot training and rehabilitation. Here are the highlights of today's episode:03:59 How Our Body Feeds Into Mental Experiences08:59 How People Can Shift Through Movement and Fascial Engagement15:17 Walking as An Access Point to Health26:04 How Fascia and Movement Informs Our Genetic Expression40:16 Supporting Fascia and Microvasculature46:33 Reintegrating Body with Space51:43 ConclusionIf you wish to learn more from Dr. Emily Splichal and Naboso, you may do so through the following channels:Website: https://www.naboso.com/Instagram: https://www.instagram.com/naboso_technology/YouTube: Master Movement with Naboso______________________________________________________Keep yourself up to date on The DNA Talks Podcast! Follow our socials below:The DNA Talks Podcast Instagram: @dnatalkspodcastThe DNA Company Instagram: @thednacoThe DNA Company's Official Tiktok Account: @thednaco3______________________________________________________Medical Disclaimer: The information provided in this communication is for general informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read here. If you think you may have a medical emergency, call your doctor or 911 immediately.

Today we are featuring two articles that relate to moving genetics into mainstream healthcare. In our first segment, we discuss polygenic risk scores and the transition from research to clinical use. Our second segment focuses on hypermobility Ehlers Danlos Syndrome and the triaging of clinical referrals.    Segment 1: Readiness and leadership for the implementation of polygenic risk scores: Genetic healthcare providers' perspectives in the hereditary cancer context   Dr Rebecca Purvis is a post-doctoral researcher, genetic counsellor, and university lecturer and coordinator at The Peter MacCallum Cancer Centre and The University of Melbourne, Melbourne, Australia. Dr Purvis focuses on health services delivery, using implementation science to design and evaluate interventions in clinical genomics, risk assessment, and cancer prevention.   In this segment we discuss: - Why leadership and organizational readiness are critical to successful clinical implementation of polygenic risk scores (PRS). - How genetic counselors' communication skills position them as key leaders as PRS moves from research into practice. - Readiness factors healthcare systems should assess, including culture, resources, and implementation infrastructure. - Equity, standardization, and implementation science as essential tools for responsible and sustainable PRS adoption. Segment 2: A qualitative investigation of Ehlers-Danlos syndrome genetics triage   Kaycee Carbone is  a genetic counselor at Boston Children's Hospital in the Division of Genetics and Genomics as well as the Vascular Anomalies Center. Her clinical interests include connective tissue disorders, overgrowth conditions, and somatic and germline vascular anomaly conditions. She completed my M.S. in Genetic Counseling at the MGH Institute of Health Professions in 2023. The work she discusses here, "A qualitative investigation of Ehlers-Danlos syndrome genetics triage," was completed as part of a requirement for this graduate program.    In this segment we discuss: - Why genetics clinics vary widely in how they triage referrals for hypermobile Ehlers-Danlos syndrome (hEDS). - How rising awareness of hEDS has increased referral volume without clear guidelines for diagnosis and care. - The ethical and emotional challenges genetic counselors face when declining hEDS referrals. - The need for national guidelines and clearer care pathways to improve access and coordination for EDS patients. Would you like to nominate a JoGC article to be featured in the show? If so, please fill out this nomination submission form here. Multiple entries are encouraged including articles where you, your colleagues, or your friends are authors.   Stay tuned for the next new episode of DNA Dialogues! In the meantime, listen to all our episodes Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “DNA Dialogues”.    For more information about this episode visit dnadialogues.podbean.com, where you can also stream all episodes of the show. Check out the Journal of Genetic Counseling here for articles featured in this episode and others.    Any questions, episode ideas, guest pitches, or comments can be sent into DNADialoguesPodcast@gmail.com.    DNA Dialogues' team includes Jehannine Austin, Naomi Wagner, Khalida Liaquat, Kate Wilson and DNA Today's Kira Dineen. Our logo was designed by Ashlyn Enokian. Our current intern is Stephanie Schofield.

Send us a textIn this episode of the Incubator, Betsy Crouch and David McCulley interview Dr. Wendy Chung, a leader in clinical genetics and child health research. They discuss her journey into genomics, the challenges faced in her career as a physician scientist, the importance of early mentorship, and her research interests, particularly in congenital diaphragmatic hernia (CDH). Dr. Chung shares insights on the complexities of genetic disorders and the need for innovative approaches in treatment and diagnosis. She discusses her experiences with newborn screening and the evolution of genetic screening for rare diseases, emphasizing the importance of advocacy for children's health research. The conversation highlights the impact of patient stories in research and concludes with personal insights into family activities and the importance of maintaining a balance between work and personal life.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textHow seasonal changes in light and dietary unsaturated fats affect circadian rhythms in mammals.Topics Discussed:Evolutionary context of circadian rhythms: All organisms have adapted to Earth's 24-hour day for survival, with internal clocks slightly offset and adjusted by environmental cues.Molecular clock mechanism: Involves a feedback loop where proteins turn on/off genes, lasting ~24 hours, regulated by phosphorylation and degradation for timing precision.Genetic variations in sleep: Families with mutations in clock genes like PER2 cause extreme morning lark behavior, altering protein stability and period length by hours.Light entrainment: Morning light shortens human clocks (average 24.2 hours) to match 24-hour days; seasonal day length changes require gradual adjustments.Food & metabolic links: Seasonal food scarcity/abundance affects clock via glucose and fatty acids competing for protein modifications, as shown in diabetic mouse models.Role of unsaturated fats: Paper finds MUFA/PUFA ratios in diet alter phosphorylation of clock proteins, speeding or slowing adaptation to winter/summer light cycles in mice.Modern environmental impacts: Artificial light extends “daytime” signals, while constant food access erases seasonal patterns, contributing to obesity and diabetes risks.Jet lag & adaptations: Sudden time shifts mimic seasonal experiments; high-sugar/fat intake may phenocopy genetic effects to aid adjustment, though not recommended for health.Practical Takeaways:Expose yourself to morning natural light to help synchronize your internal clock and improve daily energy.Consume main meals during daylight hours and avoid late-night eating to align with natural metabolic rhythms.Limit evening screen time to reduce artificial blue light disrupting sleep onset.Consider varying diet seasonally, favoring diverse, whole foods to mimic natural availability patterns for better health.About the guest: Louis Ptacek, MD is a neurologist and professor at the University of California, San Francisco. He researches inherited neurological diseases and sleep traits, including genetic variations causing extreme early rising.Related Episode:M&M 237: Circadian Biology: Genetics, Behavior, Metabolism, Light, Oxygen & Melatonin | Joseph Takahashi*Not medical advice.Support the showAffiliates: Lumen device to optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts

Allergy Elimination • Increased Energy • Parasite Cleansing • Pain Relief • Physical Strengthening • Improved Respiration • Better Digestion • Sharper Thinking • Deeper Sleep • Straighter Posture • Stronger Immunity • Clearer Skin • Thicker Hair • Fewer Migraines • Clearer Boundaries • Healthier Relationships • Heightened Manifestation • Greater AbundanceBiofield tuning through DNA activation is an increasingly well-received form of energy healing capable of stimulating a self-healing potential in the human genetic blueprint.Check out this extraordinary testimonial by one of the luminaries in the field of frequency medicine …The Regenetics approach to sound healing honors the total bio-spiritual spectrum while focusing on healing as a transformative process of “wholing.”https://www.phoenixregenetics.org“Anyone with a desire to elevate their energetic and physical potential needs to understand Luckman's work and experience it for themselves.” —Dr. Julie TwoMoon“Both fascinating and an astounding, perhaps even world-changing theory.” —NEW DAWN“Luckman has succinctly and elegantly provided a comprehensible intellectual framework for understanding the profound role of DNA in healing and transformation.” —Brendan D. Murphy, author of THE GRAND ILLUSIONBenefits can range from allergy relief and greater energy, to more harmonious relationships and added abundance, to empowerment and renewed life purpose. Since DNA interfaces with all physical, mental, emotional and spiritual aspects of our being, the possibilities are limitless!Expand your concept of the possible by watching the videos below for a quick intro to the art and science of “ener-genetically” rewriting yourself with this “revolutionary” 4-stage Method:1️⃣ Potentiation Electromagnetic Repatterning2️⃣ Articulation Bioenergy Enhancement3️⃣ Elucidation Triune Activation4️⃣ Transcension Bioenergy Crystallization Thank you for subscribing. Leave a comment or share this episode.

As we know there is an elevated interest in wild turkey science within the turkey hunting community, we are working to bring you numerous updates and research summaries from the 13th National Wild Turkey Symposium in Kansas City, Missouri. This episode includes conversations with authors or presenters from papers included in the "Wild Turkey Genetics" session: "Role of kinship in sociality of female eastern wild turkeys" — Chamberlain et al. (https://wildlife.onlinelibrary.wiley.com/doi/10.1002/wsb.1630) "Genetic structuring and within-flock relatedness of eastern wild turkeys" — Watkins et al. (Presented by Chamberlain) (https://wildlife.onlinelibrary.wiley.com/doi/10.1002/wsb.1622) Additional guests include the NWTF's Ricky Lackey. While we were not able to sit down and have further conversations about the following paper that also was included in the session about wild turkey genetics, please check out the following research paper titled "Investigating the role of management decisions in subspecies hybridization across the wild turkey's range" — Beckman et al. (https://wildlife.onlinelibrary.wiley.com/doi/10.1002/wsb.1625) To view the full symposium agenda, visit www.wildturkeysymposium.org.

Episode 336 In an unlikely turn of events, orcas and dolphins have been observed teaming up - to hunt and kill massive chinook salmon in the pacific. Given that orcas sometimes prey on dolphins, what's going on? Despite the promising signs of cooperation between these two species, there may be something less heartwarming at play. We dig into the findings and discuss other surprising ways animals cooperate with each other. From schizophrenia to bipolar disease, autism to OCD, many mental conditions are classified into different categories. But in the largest study of its kind, it's been discovered that 14 different disorders fall into just five genetic groups. The finding could explain why people are often diagnosed with multiple psychiatric conditions at once - and bring comfort to those who are. Could it also help us find better treatments? Exploding stars might be to thank for our very existence. It's thought that supernovae may spew out the heavy elements required for the creation of planets and the emergence of life. A new model shows this is possible - and may help us figure out where to look next for alien life. Could this open up a new field of cosmic ecology? Plus, news of a strange new kind of star from the James Webb Telescope. Black hole stars may explain a running mystery about odd galaxies spotted by the telescope, called little red dots.  Hosted by Rowan Hooper and Penny Sarchet, with guests Alec Luhn, Michael Le Page and Alex Wilkins. To read more about these stories, visit https://www.newscientist.com/ Learn more about your ad choices. Visit megaphone.fm/adchoices

Live at the Zenos Health Summit, I've presented on stage why 22 years of mortality research and 371 million data points prove that every disease pathway has its roots in the absence of oxygen and the specific raw materials your body needs to function. I've also exposed fallacies around genetically-inherited diseases, why lowering homocysteine is critical for cardiovascular health, and walked through Dana White's transformation from brittle hypertensive on three blood pressure medications to canceling his heart ablation procedure entirely. The big data doesn't lie, and neither does human physiology when you finally give what it needs. What would you do differently if you knew exactly what was shortening your life? CLICK HERE TO BECOME GARY'S VIP!: https://bit.ly/4ai0Xwg Thank you to our partners H2TABS: “ULTIMATE10” FOR 10% OFF: https://bit.ly/4hMNdgg BODYHEALTH: “ULTIMATE20” FOR 20% OFF: http://bit.ly/4e5IjsV BAJA GOLD: "ULTIMATE10" FOR 10% OFF: https://bit.ly/3WSBqUa COLD LIFE: THE ULTIMATE HUMAN PLUNGE: https://bit.ly/4eULUKp WHOOP: JOIN AND GET 1 FREE MONTH!: https://bit.ly/3VQ0nzW AION: “ULTIMATE10” FOR 10% OFF: https://bit.ly/4h6KHAD A-GAME: “ULTIMATE15” FOR 15% OFF: http://bit.ly/4kek1ij PEPTUAL: “TUH10” FOR 10% OFF: https://bit.ly/4mKxgcn CARAWAY: “ULTIMATE” FOR 10% OFF: https://bit.ly/3Q1VmkC HEALF: 10% OFF YOUR ORDER: https://bit.ly/41HJg6S RHO NUTRITION: “ULTIMATE15” FOR 15% OFF: https://bit.ly/44fFza0 GOPUFF: GET YOUR FAVORITE SNACK!: https://bit.ly/4obIFDCGENETIC METHYLATION TEST (UK ONLY): https://bit.ly/48QJJrk GENETIC TEST (USA ONLY): ⁠https://bit.ly/3Yg1Uk9 Watch  the “Ultimate Human Podcast” every Tuesday & Thursday at 9AM EST: YouTube: https://bit.ly/3RPQYX8 Podcasts: https://bit.ly/3RQftU0 Connect with Gary Brecka Instagram: https://bit.ly/3RPpnFs TikTok: https://bit.ly/4coJ8fo X: https://bit.ly/3Opc8tf Facebook: https://bit.ly/464VA1H LinkedIn: https://bit.ly/4hH7Ri2 Website: https://bit.ly/4eLDbdU Merch: https://bit.ly/4aBpOM1 Newsletter: https://bit.ly/47ejrws Ask Gary: https://bit.ly/3PEAJuG Timestamps 00:00 Intro of Show 03:34 Presence of Oxygen = Absence of Disease 13:15 The Methylation Pathway Chart 13:28 Fallacies on Genetically-Inherited Diseases 14:38 Attention “Overload” (not Deficit) Disorder 18:15 What Drives Anxiety (and Other Mental Illnesses)? 25:59 Inability to Break Down Homocysteine 27:39 Dana White's Transformation 35:48 Catecholamines as Waking Neurotransmitters 38:22 The Gut-Brain Connection 43:14 The Genesis of Disease 46:01 Insulin Resistance 47:17 Importance of Hydrogen in the Human Body 55:56 Gary's Morning Routine 57:55 Join the TUH VIP 1:02:49 Extended Life Expectancy = Absence of Processed Food 1:06:10 ADD & ADHD Causes and Treatments 1:15:15 Managing Oxygen 1:17:27 Should You Take NAD+? 1:21:07 Rapid Weight Loss is a Toxic Process The Ultimate Human with Gary Brecka Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user's own risk. The Content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of the Gladden Longevity Podcast, Dr. Jeffrey Gladden and Kashif Khan discuss the intersection of genetics, health, and longevity. Kashif shares his personal journey from illness to founding the DNA company, emphasizing the importance of personalized medicine and genetic testing. They explore the unique health challenges faced by women, the impact of trauma and stress on health, and the need for individualized approaches in biohacking. The conversation highlights the significance of understanding hormone metabolism and the role of genetics in parenting, ultimately advocating for a comprehensive analysis of health to achieve optimal outcomes.   For Audience ·       Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/ !    Takeaways ·        Genetics play a crucial role in understanding individual health. ·        Personalized medicine is essential for effective treatment. ·        Women face unique health challenges that are often overlooked. ·        Understanding hormone metabolism is key to preventing health issues. ·        Trauma and stress can significantly impact health outcomes. ·        Biohacking should be individualized, not one-size-fits-all. ·        Nervous system regulation is vital for overall health. ·        Genetic predispositions can reveal superpowers and vulnerabilities. ·        Parenting can be enhanced through understanding children's genetics. ·        Comprehensive analysis is necessary for accurate health assessments.     Chapters 00:00 Introduction to Kashif and His Journey 05:37 The Role of Genetics in Health 08:12 Understanding Individual Health Through Multiple Lenses 11:12 The Importance of Personalized Medicine 14:00 The Intersection of Genetics and Trauma 17:04 Navigating the Biohacking Landscape 19:54 The Impact of Stress and Anxiety on Health 22:59 Transforming Trauma into Superpowers 29:04 The Impact of Social Media on Identity 30:01 Understanding Genetic Potential in Children 32:32 Personalized Parenting Through Genetic Insights 38:39 Women's Health: A Neglected Area 41:25 Hormonal Health and Cancer Risks 47:32 The Precision of Hormonal Treatments   To learn more about Kashif: Email:  kash@kashkhanofficial.com Website: https://kashkhanofficial.com/   Reach out to us at:    Website: https://gladdenlongevity.com/     Facebook: https://www.facebook.com/Gladdenlongevity/    Instagram: https://www.instagram.com/gladdenlongevity/?hl=en     LinkedIn: https://www.linkedin.com/company/gladdenlongevity    YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw       Gladden Longevity Podcast Disclosures Production & Independence The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas. Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements. Medical Disclaimer The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content. The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options. Use of information from this podcast and any linked materials is at the listener's own risk. Podcast Guest Disclosures Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team. Sponsorships & Affiliate Disclosures To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes. We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented. Additional Note on Content Integrity All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.

This episode with Dr. David McCarty-Caplan touches on so many profound and heartfelt areas, carried by the radical vulnerability, honesty, and compassion he brings to the conversation. David generously shares about his reunion with his Colombian birth family-- first on his own, and later with his children and partner. We explore how his kids embraced reunion and modeled openness, curiosity and love with his family, and how their presence and perspective helped guide and teach him throughout the process. David also reflects on his identity as a Jewish Colombian adoptee and his powerful work community building with and for Jewish adoptees of color.  Dr. David McCarty-Caplan BioDr. David McCarty-Caplan (PhD) is a researcher, educator, writer, and consultant whose work sits at the intersection of identity, belonging, and social justice. Born in Bogotá, Colombia and adopted into a white Jewish family in the United States, David's life has been shaped by questions of race, family, and home. These experiences continue to inform his passion for helping adoptees and their families navigate the complex layers of identity, racism, and connection that often accompany adoption. Drawing on his background as a social work researcher and educator, David brings both personal insight and professional rigor to his work with organizations, communities, and families. He is especially interested in how people and institutions can create spaces where all feel seen and valued. David lives in Los Angeles with his wife and their two children, ages 12 and 10. As a husband, father, and adoptee, he is continually exploring what it means to nurture belonging — in his family, in his work, and in the broader world.https://www.shadesofbelonging.com/Co-Hosts: Nari Baker & Robyn ParkMusic: Mike Marlatt & Paul GulledgeAudio Production: Frederico Soler FernándezArtwork: Dalhe KimListen on: iTunes & SpotifyInstagram: @laboroflovepodcastSupport via Venmo: @laboroflovepodcast

In this solo livestream episode, Jason Cavness walks small business owners through the HR laws you must follow when you have 49 or fewer employees. Jason draws from more than 30 years of HR experience, 25 years as a retired U.S. Army officer, and over a decade working with startups to explain complicated HR rules in a simple, practical way.  Jason covers what federal government actually requires, why most HR mistakes come from confusion rather than bad intent, and how ignoring even one rule can lead to fines, audits, lawsuits, and massive headaches for small business owners.  Using real examples, stories from his career, and questions from livestream viewers, Jason breaks down what every employer needs to know: overtime rules, payroll tax obligations, discrimination laws, onboarding requirements, union rules, ADA accommodations, pregnancy protections, military employment rights, OSHA issues, misclassification risks, and more. If you're a founder, small business owner, or early-stage startup leader, this episode gives you a straightforward roadmap for staying compliant and protecting your business before something goes wrong.  Topics Discussed • Why HR feels complicated  and why it really isn't  • The real reason most small businesses get fined  • Drug-Free Workplace Act and who it does and does not apply to  • Audio monitoring vs video monitoring rules  • Polygraph testing and the extremely rare cases where it's allowed  • Military employment rights and what employers must provide  • Workplace safety, chemical safety sheets, and OSHA basics • Employee rights to discuss wages, schedules, and working conditions • Equal Pay Act misunderstandings and why negotiation habits matter • Minimum wage, overtime, exempt vs non-exempt rules • Why you must pay overtime even when you tell someone not to work it • I-9 verification, E-Verify, and immigration compliance • Payroll tax responsibilities • ADA and reasonable accommodation requirements • Pregnancy discrimination and common employer mistakes • Genetic information discrimination and health insurance issues • Title VII Civil Rights Act protections • LGBTQ workplace protections  • Age discrimination rules and why age 40 is the legal threshold • COBRA continuation for companies offering health benefits  • Worker misclassification and how calling someone a contractor doesn't make them one • Why unions form and how employers accidentally trigger unionization • What CavnessHR is building to automate HR and prevent these problems Support CavnessHR CavnessHR is building an AI-native HR system for small businesses with 49 or fewer employees  automated compliance plus access to a dedicated HR Business Partner.  Invest on Wefunder: https://wefunder.com/cavnesshr Download 7 free eBooks based on The Jason Cavness Experience: https://www.buildcavnesshr.com/ebooks Join the Builders Club: https://www.buildcavnesshr.com/ Connect with Jason Cavness LinkedIn: https://www.linkedin.com/in/jasoncavness/ https://www.linkedin.com/in/jasoncavness Instagram: https://www.instagram.com/jasoncavness TikTok: https://www.tiktok.com/@jasoncavness Podcast: https://www.thejasoncavnesssexperience.com  

Mandioca todo mundo conhece, certo? Mas, você já comeu cacau? Não, não o chocolate, o cacau mesmo. E o Cupuaçu? Conversamos sobre a importância cultural, versatilidade e potencial tóxico desses alimentos tão caracterísico do norte do Brasil. Patronato do SciCast: 1. Patreon SciCast 2. Apoia.se/Scicast 3. Nos ajude via Pix também, chave: contato@scicast.com.br ou acesse o QRcode: Sua pequena contribuição ajuda o Portal Deviante a continuar divulgando Ciência! Contatos: contato@scicast.com.br https://twitter.com/scicastpodcast https://www.facebook.com/scicastpodcast https://www.instagram.com/PortalDeviante/ Fale conosco! E não esqueça de deixar o seu comentário na postagem desse episódio! Expediente: Produção Geral: Tarik Fernandes e André Trapani Equipe de Gravação: Tarik Fernandes, Marcelo de Matos, Gustavo Rebello, Lenin Machado, Daniela Andrade, Diego Squinello Citação ABNT: Scicast #672: Sabores e Tradições Amazônicas: Mandioca, Cacau e Cupuaçu. Locução: Tarik Fernandes, Gustavo Rebello, Lenin Machado, Daniela Andrade, Diego Squinello. [S.l.] Portal Deviante, 09/12/2025. Podcast. Disponível em: https://www.deviante.com.br/podcasts/scicast-672 Imagem de capa: https://brasilagosto.org/cupuacu/ Referências e Indicações EMBRAPA (Empresa Brasileira de Pesquisa Agropecuária). "Açaí: o fruto da Amazônia". Disponível em: https://www.embrapa.br/tema-acai SILVA, S. M. et al. "Características nutricionais e funcionais do açaí (Euterpe oleracea Mart.)". Revista Brasileira de Fruticultura, 2014. SEBRAE (Serviço Brasileiro de Apoio às Micro e Pequenas Empresas). "Cadeia produtiva do açaí no Brasil". Disponível em: https://www.sebrae.com.br/sites/PortalSebrae/ufs/pa/artigos/a-cadeia-produtiva-do-acai JUNQUEIRA, N. T. V.; ROCHA, F. S. "Botânica e fruticultura do açaí". Revista Brasileira de Fruticultura, 2016. CAVALCANTE, P. B. "Frutas comestíveis da Amazônia". Belém: Museu Paraense Emílio Goeldi, 2010. MUÑIZ-MIRET, N. et al. "Genetic diversity of Euterpe oleracea Mart. in the Amazon". Scientia Agricola, 1996. INSTITUTO SOCIOAMBIENTAL (ISA). "Povos e comunidades tradicionais da Amazônia". Disponível em: https://www.socioambiental.org Canal Rural: “Pará exporta mais de 61 mil toneladas de açaí por ano, aponta estudo” Disponível em: https://www.canalrural.com.br/agricultura/para-exporta-mais-de-61-mil-toneladas-de-acai-por-ano-aponta-estudo Agência Pará: “Dia do Açaí: Pará segue na liderança nacional com mais de 90% da produção brasileira” Disponível em: https://agenciapara.com.br/noticia/59374/dia-do-acai-para-segue-na-lideranca-nacional-com-mais-de-90-da-producao-brasileira Estado de Minas: “Açaí brasileiro vira febre fora do país e ganha o mundo” Disponível em: https://www.em.com.br/app/noticia/economia/2023/10/15/internas_economia%2C1576667/acai-brasileiro-vira-febre-fora-do-pais-e-ganha-o-mundo.shtml Acai Berry Market Set to Thrive at an Impressive 11.5% CAGR Disponível em: https://www.newstrail.com/acai-berry-market-set/ BARBOSA, A. P. et al. "Compostos bioativos do jambu: uma revisão". Revista Brasileira de Farmacognosia, 2016. SILVA, S. M. et al. "Propriedades medicinais e culinárias do jambu (Acmella oleracea)". Revista Brasileira de Plantas Medicinais, 2015. Sugestões de vídeos: A lenda da mandioca (recomendado para crianças): https://www.youtube.com/watch?v=zSBsJTSX3AE Sugestões de links: Sobre diferenciar mandioca brava e mansa: https://www.cpt.com.br/dicas-cursos-cpt/e-possivel-diferenciar-mandioca-brava-da-de-mesa https://www.embrapa.br/embrapa-no-cirio/jambu https://ainfo.cnptia.embrapa.br/digital/bitstream/item/56524/1/n12-etnocultivo-do-jambu-p.pdfSee omnystudio.com/listener for privacy information.

This week we are talking about Pancreatic cancer.  This is a type of cancer that begins as a growth of cells in the pancreas. The pancreas lies behind the lower part of the stomach. It makes enzymes that help digest food and hormones that help manage blood sugar. The most common type of pancreatic cancer is pancreatic ductal adenocarcinoma. This type begins in the cells that line the ducts that carry digestive enzymes out of the pancreas. Pancreatic cancer rarely is found at its early stages when the chance of curing it is greatest. This is because it often doesn't cause symptoms until after it has spread to other organs. Your health care team considers the extent of your pancreatic cancer when creating your treatment plan. Treatment options may include surgery, chemotherapy, radiation therapy or a mix of these. Pancreatic cancer often doesn't cause symptoms until the disease is advanced. When they happen, signs and symptoms of pancreatic cancer may include: Belly pain that spreads to the sides or back. Loss of appetite. Weight loss. Yellowing of the skin and the whites of the eyes, called jaundice. Light-colored or floating stools. Dark-colored urine. Itching. New diagnosis of diabetes or diabetes that's getting harder to control. Pain and swelling in an arm or leg, which might be caused by a blood clot. Tiredness or weakness. It's not clear what causes pancreatic cancer. Doctors have found some factors that might raise the risk of this type of cancer. These include smoking and having a family history of pancreatic cancer. Understanding the pancreas The pancreas is about 6 inches (15 centimeters) long and looks something like a pear lying on its side. It releases hormones, including insulin. These hormones help the body process the sugar in the foods you eat. The pancreas also makes digestive juices to help the body digest food and take in nutrients. How pancreatic cancer forms Pancreatic cancer happens when cells in the pancreas develop changes in their DNA. A cell's DNA holds the instructions that tell a cell what to do. In healthy cells, the instructions tell the cells to grow and multiply at a set rate. The cells die at a set time. In cancer cells, the changes give different instructions. The changes tell the cancer cells to make many more cells quickly. Cancer cells can keep living when healthy cells would die. This causes there to be too many cells. The cancer cells might form a mass called a tumor. The tumor can grow to invade and destroy healthy body tissue. In time, cancer cells can break away and spread to other parts of the body. Most pancreatic cancer begins in the cells that line the ducts of the pancreas. This type of cancer is called pancreatic ductal adenocarcinoma or pancreatic exocrine cancer. Less often, cancer can form in the hormone-producing cells or the neuroendocrine cells of the pancreas. These types of cancer are called pancreatic neuroendocrine tumors or pancreatic endocrine cancer. Risk factors Factors that might raise the risk of pancreatic cancer include: Smoking. Type 2 diabetes. Chronic inflammation of the pancreas, called pancreatitis. Family history of DNA changes that can increase cancer risk. These include changes in the BRCA2 gene, Lynch syndrome and familial atypical multiple mole melanoma (FAMMM) syndrome. Family history of pancreatic cancer. Obesity. Older age. Most people with pancreatic cancer are over 65. Drinking a lot of alcohol. As pancreatic cancer progresses, it can cause complications such as: Weight loss. People with pancreatic cancer might lose weight as the cancer uses more of the body's energy. Nausea and vomiting caused by cancer treatments or a cancer pressing on the stomach might make it hard to eat. Sometimes the body has trouble getting nutrients from food because the pancreas isn't making enough digestive juices. Jaundice. Pancreatic cancer that blocks the liver's bile duct can cause jaundice. Signs include yellowing of the skin and the whites of the eyes. Jaundice can cause dark-colored urine and pale-colored stools. Jaundice often occurs without belly pain. If the bile duct is blocked, a plastic or metal tube called a stent can be put inside it. The stent helps hold the bile duct open. This is done using a procedure called endoscopic retrograde cholangiopancreatography, also called ERCP. During ERCP, a health care professional puts a long tube with a tiny camera, called an endoscope, down the throat. The tube goes through the stomach and into the upper part of the small intestine. The health professional puts a dye into the pancreatic ducts and bile ducts through a small tube that fits through the endoscope. The dye helps the ducts show up on imaging tests. The health professional uses those images to place a stent at the right spot in the duct to help hold it open. Pain. A growing tumor may press on nerves in your abdomen, causing pain that can become severe. Pain medications can help you feel more comfortable. Treatments, such as radiation and chemotherapy, might help slow tumor growth and provide some pain relief. When medicines aren't helping, a health care professional might suggest a celiac plexus block. This procedure uses a needle to put alcohol into the nerves that control pain in the belly. The alcohol stops the nerves from sending pain signals to the brain. Bowel blockage. Pancreatic cancer can grow into or press on the first part of the small intestine, called the duodenum. This can block the flow of digested food from the stomach into the intestines. A health care professional might suggest putting a tube called a stent in the small intestine to hold it open. Sometimes, it might help to have surgery to place a feeding tube. Or surgery can attach the stomach to a lower part of the intestines where the cancer isn't causing a blockage. Prevention Screening for people with a high risk of pancreatic cancer Screening uses tests to look for signs of pancreatic cancer in people who don't have symptoms. It might be an option if you have a very high risk of pancreatic cancer. Your risk might be high if you have a strong family history of pancreatic cancer or if you have an inherited DNA change that increases the risk of cancer. Pancreatic cancer screening might involve imaging tests, such as MRI and ultrasound. These tests are generally repeated every year. The goal of screening is to find pancreatic cancer when it's small and most likely to be cured. Research is ongoing, so it's not yet clear whether screening can lower the risk of dying of pancreatic cancer. There are risks to screening. This includes the chance of finding something that requires surgery but later turns out to not be cancer. Talk about the benefits and risks of pancreatic cancer screening with your health care team. Together you can decide whether screening is right for you. Genetic testing for cancer risk If you have a family history of pancreatic cancer, discuss it with a health care professional. The health professional can review your family history and help you understand whether genetic testing might be right for you. Genetic testing can find DNA changes that run in families and increase the risk of cancer. If you're interested in genetic testing, you might be referred to a genetic counselor or other health care professional trained in genetics. Ways to lower risk You might reduce your risk of pancreatic cancer if you: Stop smoking. If you smoke, talk to a member of your health care team about ways to help you stop. These might include support groups, medicines and nicotine replacement therapy. Maintain a healthy weight. If you are at a healthy weight, work to maintain it. If you need to lose weight, aim for a slow, steady weight loss of 1 to 2 pounds (0.5 to 1 kilogram) a week. To help you lose weight, exercise most days of the week. Slowly increase the amount of exercise you get. Choose a diet rich in vegetables, fruit and whole grains with smaller portions.  (CREDITS: MAYO CLINIC)

Mandioca todo mundo conhece, certo? Mas, você já comeu cacau? Não, não o chocolate, o cacau mesmo. E o Cupuaçu? Conversamos sobre a importância cultural, versatilidade e potencial tóxico desses alimentos tão caracterísico do norte do Brasil. Patronato do SciCast: 1. Patreon SciCast 2. Apoia.se/Scicast 3. Nos ajude via Pix também, chave: contato@scicast.com.br ou acesse o QRcode: Sua pequena contribuição ajuda o Portal Deviante a continuar divulgando Ciência! Contatos: contato@scicast.com.br https://twitter.com/scicastpodcast https://www.facebook.com/scicastpodcast https://www.instagram.com/PortalDeviante/ Fale conosco! E não esqueça de deixar o seu comentário na postagem desse episódio! Expediente: Produção Geral: Tarik Fernandes e André Trapani Equipe de Gravação: Tarik Fernandes, Marcelo de Matos, Gustavo Rebello, Lenin Machado, Daniela Andrade, Diego Squinello Citação ABNT: Scicast #672: Sabores e Tradições Amazônicas: Mandioca, Cacau e Cupuaçu. Locução: Tarik Fernandes, Gustavo Rebello, Lenin Machado, Daniela Andrade, Diego Squinello. [S.l.] Portal Deviante, 09/12/2025. Podcast. Disponível em: https://www.deviante.com.br/podcasts/scicast-672 Imagem de capa:  https://brasilagosto.org/cupuacu/ Referências e Indicações EMBRAPA (Empresa Brasileira de Pesquisa Agropecuária). “Açaí: o fruto da Amazônia”. Disponível em: https://www.embrapa.br/tema-acai SILVA, S. M. et al. “Características nutricionais e funcionais do açaí (Euterpe oleracea Mart.)”. Revista Brasileira de Fruticultura, 2014. SEBRAE (Serviço Brasileiro de Apoio às Micro e Pequenas Empresas). “Cadeia produtiva do açaí no Brasil”. Disponível em: https://www.sebrae.com.br/sites/PortalSebrae/ufs/pa/artigos/a-cadeia-produtiva-do-acai JUNQUEIRA, N. T. V.; ROCHA, F. S. “Botânica e fruticultura do açaí”. Revista Brasileira de Fruticultura, 2016. CAVALCANTE, P. B. “Frutas comestíveis da Amazônia”. Belém: Museu Paraense Emílio Goeldi, 2010. MUÑIZ-MIRET, N. et al. “Genetic diversity of Euterpe oleracea Mart. in the Amazon”. Scientia Agricola, 1996. INSTITUTO SOCIOAMBIENTAL (ISA). “Povos e comunidades tradicionais da Amazônia”. Disponível em: https://www.socioambiental.org Canal Rural: “Pará exporta mais de 61 mil toneladas de açaí por ano, aponta estudo” Disponível em: https://www.canalrural.com.br/agricultura/para-exporta-mais-de-61-mil-toneladas-de-acai-por-ano-aponta-estudo Agência Pará: “Dia do Açaí: Pará segue na liderança nacional com mais de 90% da produção brasileira” Disponível em: https://agenciapara.com.br/noticia/59374/dia-do-acai-para-segue-na-lideranca-nacional-com-mais-de-90-da-producao-brasileira Estado de Minas: “Açaí brasileiro vira febre fora do país e ganha o mundo” Disponível em: https://www.em.com.br/app/noticia/economia/2023/10/15/internas_economia%2C1576667/acai-brasileiro-vira-febre-fora-do-pais-e-ganha-o-mundo.shtml Acai Berry Market Set to Thrive at an Impressive 11.5% CAGR Disponível em: https://www.newstrail.com/acai-berry-market-set/ BARBOSA, A. P. et al. “Compostos bioativos do jambu: uma revisão”. Revista Brasileira de Farmacognosia, 2016. SILVA, S. M. et al. “Propriedades medicinais e culinárias do jambu (Acmella oleracea)”. Revista Brasileira de Plantas Medicinais, 2015. Sugestões de vídeos: A lenda da mandioca (recomendado para crianças): https://www.youtube.com/watch?v=zSBsJTSX3AE Sugestões de links: Sobre diferenciar mandioca brava e mansa: https://www.cpt.com.br/dicas-cursos-cpt/e-possivel-diferenciar-mandioca-brava-da-de-mesa https://www.embrapa.br/embrapa-no-cirio/jambu https://ainfo.cnptia.embrapa.br/digital/bitstream/item/56524/1/n12-etnocultivo-do-jambu-p.pdf

News items read by Laura Kennedy include: Genetic study reveals long isolation of early humans in southern Africa (details)(details) Ancient DNA offers new clues about early cat domestication (details)(details) New findings explain why men and women were sacrificed differently in ancient China (details)(details) Excavation reveals traces of Tlatelolca people beneath Mexico City (details)

Send us a textDr. Katherine P Callahan, neonatologist and bioethicist at Children's Hospital of Philadelphia, discusses the complexity of genetic testing in neonatal care. While the NICU serves as a launch point for genetic technologies due to high prevalence of genetic disease, genetic information is often ambiguous or uncertain rather than straightforwardly diagnostic. Variants of uncertain significance represent just one challenge—even clearly pathogenic findings may have unclear implications for individual patients, as demonstrated when parents carry the same mutation as their severely affected child. Callahan emphasizes that genetic information poses "informational hazards" requiring careful consideration of psychological and ethical impacts. She advocates for acknowledging complexity, rethinking outcomes beyond traditional measures, and embracing shared decision-making rather than standardized approaches to genomic counseling. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Leigh Ann interviews Gracia Walker, co-founder of Broc Shot, a supplement focused on sulforaphane, a powerful compound found in cruciferous vegetables. They discuss the origin story behind Broc Shot, the science behind sulforaphane, its health benefits, and the importance of quality and sustainability in the supplement industry. Gracia shares the science behind the brand, particularly regarding the impact of sulforaphane on conditions like psoriasis and its role in detoxification and inflammation management. Their conversation also highlights Broc Shot's commitment to ethical practices and environmental sustainability.Product Discount Codes + Links2025 Holistic Holiday Gift Guide: HereHerbal Face Food: Website (Discount Code: LAL30)Prolon Fast-Mimicking Program: Website (Discount Link Gives 25% off) Healing Alchemy Membership: Learn MoreGuest InfoBroc Shot - Website (Use code LEIGHANN for 20% off)Broc Shot - InstagramRelated EpisodesPodcast Ep. 215: Wade Lightheart (Bioptimizers) - Magnesium, The Master Mineral & Why Most Magnesium Supplements Fall ShortPodcast Ep. 184: Karen Hurd - A Biochemist Dives Deep Into the Science of Detoxing at a Cellular Level, Debunking Common Detox MythsPodcast Ep. 162: Dr. Stephanie Peacock - Unmasking Mold: Mast Cell Activation, Nervous System, Detox & MoreWork w/Leigh AnnLearn: What is EVOX Therapy?Book: Schedule a Session or FREE Discovery CallMembership: What is The Healing Alchemy MembershipConnect w/Me & Learn MoreWebsiteInstagramTiktokYoutube

Genetic history of dog domestication Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, researchers explore the impact of domestication on dog genetics and behavior. In this episode, we cover: •[00:00] Introduction •[01:00] Greger Larson explains how the history of gene flow between dogs and their wild relatives differs from what we know about other domestic species. •[02:38] Audrey Lin finds that low levels of wolf ancestry are found in almost two thirds of dog breeds. •[04:18] Linus Girdland Flink documents evidence of two genetic wolves on a remote Scandinavian island that may have been under human control. •[06:13] Clément Car explores how the mating systems of free-ranging village dogs could provide insight into canine domestication •[07:43] Katia Bougiouri explains how she used a statistical method to improve ancient genomes and what her results reveal about the history of inbreeding in dogs. •[09:21] Lachie Scarsbrook explains how he used museum specimens to reconstruct the history of inbreeding in German Shepherd Dogs. •[11:10] Eleanor Raffan analyzes genetic data and owner-submitted behavioral questionaries from 1,343 golden retrievers. •[12:54] Kathryn Lord finds that genetic testing cannot accurately predict canine behaviors. •[14:25] Final thoughts and conclusion. About Our Guest: Greger Larson  Professor  University of Oxford Audrey Lin  Gerstner Postdoctoral Scholar American Museum of Natural History Linus Girdland Flink  Lecturer  University of Aberdeen Clément Car  Postdoctoral Researcher University of Gdańsk Katia Bougiouri  Postdoctoral Researcher University of Copenhagen Lachie Scarsbrook Postdoctoral Researcher University of Oxford, Ludwig Maximilian University of Munich Eleanor Raffan  University Associate Professor  University of Cambridge Kathryn Lord Postdoctoral fellow  University of Massachusetts Chan Medical School View related content here: https://www.pnas.org/doi/10.1073/pnas.2528616122 https://www.pnas.org/doi/10.1073/pnas.2421768122 https://www.pnas.org/doi/10.1073/pnas.2421759122 https://www.pnas.org/doi/10.1073/pnas.2421756122 https://www.pnas.org/doi/10.1073/pnas.2416980122 https://www.pnas.org/doi/10.1073/pnas.2421755122 https://www.pnas.org/doi/10.1073/pnas.2421757122 https://www.pnas.org/doi/10.1073/pnas.2421752122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast  Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter

Send us a textHow dietary polyunsaturated fats, especially omega-6 from seed oils, influence inflammation & heart health.Topics Discussed:Polyunsaturated fatty acids (PUFAs): Omega-6 from seed oils like safflower and corn can convert to pro-inflammatory molecules, while omega-3s produce resolving ones; imbalance biases toward chronic inflammation.Inflammation regulation: Acute inflammation aids healing but requires active “on” and “off” signals from lipid mediators; chronic inflammation arises from excess omega-6, delaying resolution.Heart health & diet: High omega-6 diets worsen post-heart attack outcomes in mice by elevating pro-inflammatory lipids.Evolution & historical context: PUFAs are essential but naturally balanced in pre-industrial diets; modern processing skews ratios, contributing to diseases, as shown in early rat experiments needing minimal fats for survival.Aging & lifestyle factors: Excess omega-6 exacerbates inflammation in older mice; sleep, exercise, and balanced fats are crucial for metabolic health and enzyme function in processing lipids.Cannabis & omega-6 interaction: In mice on high omega-6 diets, CBD-rich cannabis smoke reaches the heart quickly, suppresses immune response, and weakens cardiac strain, unlike in balanced-diet controls.Genetic models: FAT-1 mice converting omega-6 to omega-3 show better healing and neuroprotection; FAT-2 mice doing the opposite exhibit liver fibrosis and metabolic issues, highlighting omega-6 excess harms.Practical Takeaways:Balance omega-6 and omega-3 intake by reducing seed oils in processed foods and increasing sources like fish or algae to support inflammation resolution and heart health.Monitor and adjust fat intake with age, as older individuals are more sensitive to omega-6 excess leading to immune dysregulation.Avoid combining high omega-6 diets with smoking, as it may impair immune and cardiac responses based on animal data.About the guest: Ganesh Halade, PhD is a cardiovascular scientist and associate professor at the University of South Florida Morsani College of Medicine.*Not medical advice.Support the showAffiliates: Lumen device to optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts

Have you ever thought about what it means to be anonymous?  Have you considered what it means that you can walk down the street or go to the grocery store or out to dinner without someone you've never met knowing your name, everything you've posted online, or your political leanings? Or when you go on a first date with someone, they'd walk in knowing your dating history, your political affiliations, your credit score or what groceries you buy? Advancements in facial recognition and a secretive startup could end privacy as we know it.  In this two-part conversation, New York Times Tech Reporter Kashmir Hill joins host Ron Steslow to discuss privacy, anonymity, facial recognition software and her book Your Face Belongs to Us: A Secretive Startup's Quest to End Privacy as We Know It. In part 1: (01:43 ) Ron and Kashmir discuss anonymity and privacy and the erosion of both in our daily lives  (00:00 ) Balancing convenience and privacy  (11:00) The origins of ClearviewAI  (13:30) Genetic determinism in the development of facial recognition  (18:20) Kashmir dives deep into the history of facial recognition software and how it developed.  (22:37) How Facebook crowdsourced training facial recognition technology (25:00) How much privacy should we have and who should be able to use facial recognition software?  Read Your Face Belongs to Us: https://bit.ly/49qsbQm Follow Ron and Kashmir  on X (formerly Twitter): https://twitter.com/RonSteslow https://twitter.com/kashhill Email your questions and thoughts to podcast@politicology.com or leave us a voicemail at ‪(202) 455-4558‬. Learn more about your ad choices. Visit megaphone.fm/adchoices

JP Dinnell talks about Discipline, Fasting, World War 2 Veterans, Serving with Jocko, and more. Get your free training from First In Nutrition: https://www.firstinnutrition.com/jppod More from JP Dinnell: https://www.jpdinnell.com/ Join the conversation on instagram JP Dinnell: http://instagram.com/jpdinnell/ Lucas Pinckard: https://www.instagram.com/lucaspinckard Bruiser Arms: https://www.instagram.com/bruiserarms Echelon Front: https://echelonfront.com/ Little Cattle Co: http://littlecattle.co On The Path Printing: https://www.instagram.com/onthepathprinting JP Dinnell is a former U.S. Navy SEAL and now a Leadership Instructor, Speaker and Strategic Advisor with Echelon Front, where he serves as Director of Experiential Leadership Training Programs. J.P. is also a pro team athlete and spokesperson for Origin Maine and Jocko Fuel, an American clothing and supplement company. J.P. has a signature Energy Drink flavor "Sour Apple Sniper" with Jocko Fuel. Jeremiah spent nearly a decade in the SEAL Teams with three combat deployments. Sent to the violent terrorist stronghold of Ar Ramadi, Iraq in 2006 with SEAL Team Three's Task Unit Bruiser, J.P. served as point man, machine gunner, and lead sniper for Delta Platoon opposite the American Sniper, Chris Kyle, who was in Charlie Platoon. For his leadership and courage under fire, JP was awarded a Silver Star, 2 Bronze Stars with Valor and the Army Commendation Medal with Valor helping Task Unit Bruiser to become the most highly decorated special operations unit of the Iraq War. He worked closely with SEAL Officers Jocko Willink, his Task Unit Commander, and Leif Babin, and was the driving force on many of the daring combat operations Jocko and Leif wrote about in Extreme Ownership. Upon his return, J.P. again worked directly for Jocko as a training instructor at Naval Special Warfare Group One Training Detachment, where he orchestrated realistic and challenging training scenarios for Special Operations Urban Combat training and Close Quarters Combat training to better prepare SEAL units for the real-world battlefield. He also served as a Combatives Instructor, Marksmanship Instructor and earned his Master Trainer Specialist qualification while helping Jocko rebuild and enhance these training programs into the highly effective platforms they are today. J.P. brings exceptional experience and frontline leadership perspective from the winning mindset and culture of Task Unit Bruiser.

In this episode of The Jordan Syatt Podcast, I speak with Elana Silber, The CEO of Sharsheret (@sharsheretofficial), a national non-profit organization that helps women and families living with breast and/or ovarian cancer.We discuss:- How Sharsheret fills the gaps in cancer support- Genetic testing and BRCA awareness- How you can get help from Sharsheret for free- How Sharsheret came to be- And more...I hope you enjoy this episode and, if you do, please leave a review on iTunes or Spotify (huge thank you to everyone who has written one so far).Finally, if you've been thinking about joining The Inner Circle but haven't yet... we have hundreds of home and bodyweight workouts for you and you can get them all here: https://www.sfinnercircle.com/

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Antonio Bianco is a world-renowned physician-scientist and expert in thyroid physiology and metabolism. In this episode, Antonio explores the complex biology of thyroid hormone production, conversion, and regulation—highlighting how deiodinase enzymes modulate hormone activity at the tissue level and why that matters for interpreting lab results. He discusses the shortcomings of relying solely on TSH as a marker of thyroid function, the ongoing debate around combination therapy with T3 and T4 versus standard T4 treatment, and how genetics, tissue sensitivity, and individual variability influence thyroid hormone metabolism. The conversation also examines how hypothyroidism affects energy, mood, cognition, and longevity; why some patients remain symptomatic despite "normal" labs; and how future research could reshape treatment paradigms. We discuss: How the thyroid produces, stores, and activates hormones like T4 and T3 to finely regulate thyroid activity [2:45]; How fasting alters thyroid hormones to conserve energy [12:45]; Action of the deiodinases: how D1, D2, and D3 enzymes control the activation and inactivation of thyroid hormones [19:15]; The normal function of thyroid hormone and the roles of the hypothalamus, pituitary gland, and deiodinases in maintaining hormonal balance [23:30]; Why understanding thyroid physiology is essential for proper diagnosis and treatment of hypothyroidism [33:45]; Testing for thyroid hormones: understanding free vs. total levels, the limitations of current T3 assays, best practices, and more [36:00]; Genetic and sex-based variability in thyroid hormone regulation and their limited clinical significance [43:45]; Hyperthyroidism: causes, symptoms, diagnosis, and treatment options [46:00]; Hypothyroidism: diagnosis and autoimmune causes of hypothyroidism [56:30]; More on hypothyroidism: diagnostic biomarkers, antibody patterns, and non-autoimmune presentations [1:05:00]; Thyroid hormone replacement therapy [1:15:15]; More on thyroid replacement strategies: exploring the evidence gaps, mortality signals, effects on lipids, and more [1:28:00]; Hypothyroidism basics: causes, antibody implications (including pregnancy), and how to make the diagnosis before choosing therapy [1:35:15]; Thyroid medication: compounded controlled-release T3, brand name versus generic, and what Antonio prescribes to newly diagnosed hypothyroid patients [1:42:45]; Redefining treatment success: why normalizing TSH isn't always enough for patients with hypothyroidism [1:54:45]; Case studies: analysis of two unusual cases of thyroid disease [1:57:00]; Dangers of supplementing with high levels of iodine, and female-specific risk of thyroid disease [2:05:45]; Case study of a patient who presents with elevated TSH but no symptoms [2:09:30]; How future research could reshape treatment, and Antonio's new book called "Rethinking Hypothyroidism" [2:13:15]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube