Podcasts about Genetic

In this episode, we explore the concept of chronotype, which reflects an individual's biological circadian timing and how it manifests in preferred sleep–wake patterns. Understanding chronotype is important because it differs from simple diurnal preference, which may be shaped by lifestyle or psychological factors rather than biology. We examine how chronotype is measured, from gold-standard laboratory methods to validated questionnaires used in field studies. The discussion also highlights the importance of accounting for sleep debt when estimating true biological timing. Finally, we consider the limitations of consumer devices and the practical implications of assessing chronotype in real-world settings. Timestamps [02:02] Understanding chronotypes [06:26] Measuring chronotypes [15:12] Genetic and environmental influences on chronotypes [28:34] Health implications of chronotypes [52:21] Practical applications Related Resources Join the Sigma email newsletter for free Subscribe to Sigma Nutrition Premium Become a member of Alan Flanagan's Alinea Nutrition Education Hub Enroll in the next cohort of our Applied Nutrition Literacy course Related previous episodes: 495, 470, 469

What if your home—or even your washing machine—was quietly wrecking your health and longevity? In this powerful episode of The Coach Debbie Potts Show, host Debbie Potts welcomes back Dr. Donald Dennis, world-renowned ENT specialist and founder of Micro Balance Health Solutions. Together, they expose the shocking ways mold and mycotoxins can silently sabotage your health—triggering chronic inflammation, sinus issues, brain fog, hormone imbalances, and even raising cancer risk. You'll learn how chronic stress, poor vagus nerve function, low stomach acid, and toxic overload create what Functional Diagnostic Nutrition calls Metabolic Chaos—and more importantly, what you can do to break the cycle. What You'll Discover in This Episode: ✅ How to test your home and body for mold (plates, urine mycotoxin tests, MTHFR genetics) ✅ Signs of mold toxicity: sinus congestion, fatigue, brain fog, hormone imbalance, and “mystery” symptoms ✅ Why 20% of people can't detox mold—and face higher cancer risk ✅ Step-by-step detox strategies: oxygen therapy, glutathione, NAC, liver support ✅ How to clean mold from clothes, HVAC systems, and hidden hotspots like washing machines ✅ Simple resilience habits to protect your brain, detox pathways, and future health Timestamps: 00:00 – Intro: Why investing in your future health matters 04:00 – Meet Dr. Donald Dennis & Micro Balance Health Solutions 07:30 – Mold exposure as the silent saboteur 11:00 – Chronic sinusitis, mycotoxins & cancer risk 16:30 – Genetic factors (MTHFR) & detox capacity 21:00 – Symptoms of mold toxicity: fatigue, brain fog, hormone issues 27:00 – Home mold testing methods (plates, tap tests, air samples) 32:00 – Urine mycotoxin testing & food concerns 38:00 – Professional remediation vs. DIY approaches 43:00 – Mold in laundry & washers: hidden dangers 48:00 – EC3 laundry additive & cleaning protocols 53:00 – Air quality fixes: foggers, candles & travel hacks 58:00 – Detox protocols: oxygen therapy, glutathione, NAC, liver cleanses 1:04:00 – Supporting vagus nerve function & digestion 1:09:00 – Reversing brain inflammation for cognitive protection 1:15:00 – Top 3 actions to safeguard your longevity

Welcome back to Beautifully Broken, where healing meets high performance. In this reflective episode, I explore the concept of bio-individuality—how each of us carries a unique blueprint of DNA that unfolds into a living, breathing expression of life. I share personal stories of illness, healing, and loss that illuminate the incredible polarity of the human experience: how some of us are biologically resilient, while others are profoundly sensitive to the same environmental triggers.We'll look at the scientific and spiritual sides of this truth—from how genetic mutations shaped survival during the Black Death and malaria epidemics, to the modern emotional weight of watching friends fall ill far too young. I unpack what it means to live with awareness of your blueprint without fear of it—to recognize that while nature may be impartial, the choices we make each day can color our genetic expression.This episode is both a meditation on grief and a celebration of life's exquisite design. It's an invitation to move through the world with kindness, curiosity, and reverence for your own human blueprint. Episode Highlights [00:00] – Opening reflection: our DNA as a living blueprint, shaped but not ruled by environment[01:12] – Defining bio-individuality and why some people seem “immune” to illness[03:35] – Honoring grief: remembering friends lost to illness and the fragility of life[05:50] – Personal reflection on cancer, Lyme, and surviving 100% of hard days[08:12] – The science of resilience: HIV resistance, the CR5 mutation, and evolutionary advantage[09:50] – The double edge of genetics: how the sickle cell trait both protects and harms[10:36] – Why our genetic diversity ensures the survival of humanity[12:48] – The power of choice, compassion, and connection in shaping our gene expression[13:44] – Closing reminder: the same individuality that causes suffering also enables miracles Links & Resources Biological Blueprint Program (Freddie's custom coaching): https://www.beautifullybroken.world/biological-blueprintBeam Minerals: https://beamminerals.com/beautifullybroken — Code: BEAUTIFULLYBROKENSilver Biotics: https://bit.ly/3JnxyDD — Code: BEAUTIFULLYBROKENLightPathLED: https://lightpathled.pxf.io/c/3438432/2059835/25794 — Code: beautifullybroken CONNECT WITH FREDDIEWork with Me: https://www.beautifullybroken.world/biological-blueprintWebsite and Store: (http://www.beautifullybroken.world) Instagram: (https://www.instagram.com/beautifullybroken.world/) YouTube: (https://www.youtube.com/@freddiekimmel Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Alien abductees and friends Truth and Bass return to dive into theories and ideas on the motivations behind traumatic and sometimes fatal alien abductions!

Dr. Robert Lustig, a world-leading expert on sugar addiction, metabolism, ultra-processed food, and artificial sweeteners, reveals how they fuel obesity, dementia, dopamine overload, and addiction - and the dangers of RFK Jr.'s health approach. Dr. Robert Lustig is a neuroendocrinologist and expert on sugar, obesity, and the science of addiction, whose groundbreaking new research reveals how the 4 major health crises are all interconnected and driven by stress. He is also the bestselling author of books such as, ‘Metabolical', and ‘Fat Chance'.  He explains: ◼️Why 29% of Americans are depressed and how food plays a hidden role ◼️How 17 seconds of pleasure can rewire your brain for lifelong addiction ◼️How the food industry secretly engineers addiction and fuels chronic disease ◼️Why 95% of Alzheimer's risk is environmental and completely preventable ◼️The dangerous link between dopamine spikes and brain cell death (00:00) Intro (02:28) The Hostage Brain (06:24) Dopamine and the Pain of Lacking Control (09:32) Tolerance Is the Start of Addiction (10:39) If You Depend on Anything, It's Bad (11:25) Is Dopamine Fasting the Cure? (13:25) Can You Rewire Your Brain Away from Sugar Cravings? (15:15) The Shocking Link Between Dementia and Diet Products (22:39) Proteins (25:32) Is Alzheimer's Genetic or Environmental? (28:56) Ketones (33:08) Ultra-Processed Foods Are Poison (34:26) Reengineering Ultra-Processed Food to Be Healthy (39:41) What Needs to Change in the USA (45:06) RFK and Vaccination in the USA (51:56) Important Message About Where You Get Your Information (55:27) Ads (56:29) Practical Steps to Fix Your Addiction (01:01:24) If You Have an Inflamed Brain, You Can't Love (01:04:08) Are Our Diets Making Us Lonely? (01:08:03) Your Vagus Nerve Needs to Be Healthy (01:08:44) Do Vagus Nerve Stimulators Work? (01:10:53) The Real Truth About Ozempic (01:16:08) Can Ozempic Help with Addiction? (01:18:45) Practical Tips to Lose Weight and Eat Less Ultra-Processed Food (01:22:02) The Dangers of Drinking Soda (01:24:22) Younger People Are Getting Cancer More Than Ever (01:27:35) Ads (01:34:29) Does Exercise Help Lower Your Sugar Consumption? (01:36:27) Almost Half of the Population Is Pre-Diabetic (01:39:38) Glucose Monitors (01:41:58) Psychedelics Follow Dr Robert: Instagram - https://bit.ly/3KkR9ce  Website - https://bit.ly/48MtKdA  You can purchase Dr Robert's book, ‘Metabolical: The Lure and the Lies of Processed Food, Nutrition, and Modern Medicine', here: https://amzn.to/48Cme56 The Diary Of A CEO: ◼️Join DOAC circle here - https://doaccircle.com/  ◼️Buy The Diary Of A CEO book here - https://smarturl.it/DOACbook  ◼️The 1% Diary is back - limited time only: https://bit.ly/3YFbJbt  ◼️The Diary Of A CEO Conversation Cards (Second Edition): https://g2ul0.app.link/f31dsUttKKb  ◼️Get email updates - https://bit.ly/diary-of-a-ceo-yt  ◼️Follow Steven - https://g2ul0.app.link/gnGqL4IsKKb  Sponsors:  Pipedrive - http://pipedrive.com/CEO    Stan Store - https://stevenbartlett.stan.store for your 14-Day free trial

As it was in the Garden of Eden, where the serpent changed the biological makeup of God's creation, so it goes again with the Fallen Ones using mad science to create an abomination on Earth. Genomic technologies are driving a vast expansion in digitalized data, from gene sequences and entire genomes that link genes to specific functions and other types of metadata for humans, other animals, plants, and microbes. A prime example includes the development of customized bioweapons. America's adversaries can direct biological attacks, specifically at US livestock and crops, to create a food security crisis. Another way is for the harvesting and pirating of DNA for racial targeting. Humanity is at a crossroads. It has to avoid both biotechnological calamity and the reign of the Antichrist. Listen to Ground Zero with Clyde Lewis M-F from 7-10 pm, pacific time on groundzeroplus.com. Call in to the LIVE show at 503-225-0860. #groundzeroplus #clydelewis #genome #DNA #biological

In this episode of SHE MD, hosts Mary Alice Haney and Dr. Thaïs Aliabadi welcome Dr. Gina Campbell from Myriad Genetics. They explore the importance of genetic testing in women's health and its potential to revolutionize cancer prevention and early detection. The discussion also provides insights into the MyRisk® Hereditary Cancer Test, the BRCA genes, and insurance coverage. Sponsor: Myriad Genetics: To learn more, visit getmyrisk.comWhat you'll learn in this episode:Genetic testing for cancer isn't just about BRCA. Myriad checks 48 cancer-causing genes, with 11 linked to breast cancer risk.Your risk isn't just in your genes. Family history, lifestyle, and even tiny DNA markers all play a role. So using tests like the MyRisk® test and Tyrer-Cuzick score or IBIS model can provide more information.Knowledge is power. Knowing your risk can lead to early screening and prevention strategies.Alcohol is a major, often overlooked cancer risk factor. Even one drink a day can significantly increase breast cancer risk.Timestamps:00:00 Introduction05:23 Genetic testing criteria and insurance coverage11:40 Importance of genetic testing for breast cancer risk16:29 Breast cancer screening recommendations and guidelines20:22 Data privacy concerns and benefits of testing24:48 Future of genetic testing and personalized medicine28:57 Advice for maximizing doctor visits and insurance31:33 How to get the MyRisk® genetic testDr. Gina Campbell's Key Takeaways:

In this Hot Topic episode of The Neurodivergent Experience, Jordan James and Simon Scott unpack sensationalist headlines, genetic blame narratives, and the ongoing misinformation war around autism.From genetic blame and parental guilt to Trump's Tylenol claims and Facebook “science,” they expose how bad headlines spread faster than real research — and why this matters for autistic people and their families.Jordan and Simon also explore:Why autism isn't a disease with a “cause,” but a form of neurodivergence shaped by synaptic developmentThe harm caused by framing autism through deficit-based narratives and severity labelsHow pseudo-scientific headlines fuel ableism and self-blame in parentsThe difference between genuine research, sensationalist headlines, and clickbait “Facebook science”The need to shift funding from “preventing autism” to supporting autistic people who already existWhy blanket statements about autism erase the vast diversity of lived experiencesThis is a fiery, passionate conversation that blends science, personal experience, and sharp critique of ableist rhetoric.Our Sponsors:

October 1st (yesterday) was International Coffee Day. In this episode, we trace coffee's journey from ancient ritual to modern science. Once a sacred brew in Ethiopia and Yemen, coffee now fuels billions daily. In 2025, research is rewriting how we should drink it. In this episode, we uncover why timing intake, keeping coffee unsweetened, and using the right brewing method matter for long-term health. We also look at new data linking clean coffee to lower risk of chronic liver disease. Coffee is more than a morning habit. It's a multi-molecule that may offer us a method and a blueprint for better well-being.00:00 — The Ubiquitous Morning Ritual01:03 — Historical Origins of Coffee02:37 — Coffee's Evolution and Global Spread05:08 — The Chemistry Behind Coffee06:31 — Genetic and Social Influences on Coffee Habits09:00 — 2025 Insights on Modern Coffee Consumption10:23 — Practical Applications for Health and Performance14:19 — Concluding Thoughts on Coffee

In this first episode of The Price of PRRS series, host Dr. Lindsay Case, PIC Technical Director of Product Sustainability, is joined by Dr. Perry Harms, PIC Health Assurance Global Director, and Dr. Derald Holtkamp, Professor in the College of Veterinary Medicine at Iowa State University, to explore the economic burden of one of the most costly diseases in swine production—Porcine Reproductive and Respiratory Syndrome (PRRS). Together, they break down what makes PRRS such a persistent challenge for producers, the factors that drive its financial impact, and why understanding the true cost is the first step toward long-term solutions.

These diseases - West Nile Virus, Lyme disease, and Rocky Mountain Spotted Fever - are named for the places where outbreaks happened. But they're also all things you get from being bitten by mosquitoes or ticks. Research: Balasubramanian, Chandana. “Rocky Mountain Spotted Fever (RMSF): The Deadly Tick-borne Disease That Inspired a Hit Movie.” Gideon. 9/1/2022. https://www.gideononline.com/blogs/rocky-mountain-spotted-fever/ Barbour AG, Benach JL2019.Discovery of the Lyme Disease Agent. mBio10:10.1128/mbio.02166-19.https://doi.org/10.1128/mbio.02166-19 Bay Area Lyme Foundation. “History of Lyme Disease.” https://www.bayarealyme.org/about-lyme/history-lyme-disease/ Caccone, Adalgisa. “Ancient History of Lyme Disease in North America Revealed with Bacterial Genomes.” Yale School of Medicine. 8/28/2017. https://medicine.yale.edu/news-article/ancient-history-of-lyme-disease-in-north-america-revealed-with-bacterial-genomes/ Chowning, William M. “Studies in Pyroplasmosis Hominis.("Spotted Fever" or "Tick Fever" of the Rocky Mountains.).” The Journal of Infectious Diseases. 1/2/1904. https://archive.org/details/jstor-30071629/page/n29/mode/1up Elbaum-Garfinkle, Shana. “Close to home: a history of Yale and Lyme disease.” The Yale journal of biology and medicine vol. 84,2 (2011): 103-8. Farris, Debbie. “Lyme disease older than human race.” Oregon State University. 5/29/2014. https://science.oregonstate.edu/IMPACT/2014/05/lyme-disease-older-than-human-race Galef, Julia. “Iceman Was a Medical Mess.” Science. 2/29/2012. https://www.science.org/content/article/iceman-was-medical-mess Gould, Carolyn V. “Combating West Nile Virus Disease — Time to Revisit Vaccination.” New England Journal of Medicine. Vol. 388, No. 18. 4/29/2023. https://www.nejm.org/doi/full/10.1056/NEJMp2301816 Harmon, Jim. “Harmon’s Histories: Montana’s Early Tick Fever Research Drew Protests, Violence.” Missoula Current. 7/20/2020. https://missoulacurrent.com/ticks/ Hayes, Curtis G. “West Nile Virus: Uganda, 1937, to New York City, 1999.” From West Nile Virus: Detection, Surveillance, and Control. New York : New York Academy of Sciences. 2001. https://archive.org/details/westnilevirusdet0951unse/ Jannotta, Sepp. “Robert Cooley.” Montana State University. 10/12/2012. https://www.montana.edu/news/mountainsandminds/article.html?id=11471 Johnston, B L, and J M Conly. “West Nile virus - where did it come from and where might it go?.” The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses vol. 11,4 (2000): 175-8. doi:10.1155/2000/856598 Lloyd, Douglas S. “Circular Letter #12 -32.” 8/3/1976. https://portal.ct.gov/-/media/departments-and-agencies/dph/dph/infectious_diseases/lyme/1976circularletterpdf.pdf Mahajan, Vikram K. “Lyme Disease: An Overview.” Indian dermatology online journal vol. 14,5 594-604. 23 Feb. 2023, doi:10.4103/idoj.idoj_418_22 MedLine Plus. “West Nile virus infection.” https://medlineplus.gov/ency/article/007186.htm National Institute of Allergy and Infectious Disease. “History of Rocky Mountain Labs (RML).” 8/16/2023. https://www.niaid.nih.gov/about/rocky-mountain-history National Institute of Allergy and Infectious Disease. “Rocky Mountain Spotted Fever.” https://www.niaid.nih.gov/diseases-conditions/rocky-mountain-spotted-fever Rensberger, Boyce. “A New Type of Arthritis Found in Lyme.” New York Times. 7/18/1976. https://www.nytimes.com/1976/07/18/archives/a-new-type-of-arthritis-found-in-lyme-new-form-of-arthritis-is.html?login=smartlock&auth=login-smartlock Rucker, William Colby. “Rocky Mountain Spotted Fever.” Washington: Government Printing Office. 1912. https://archive.org/details/101688739.nlm.nih.gov/page/ Sejvar, James J. “West Nile virus: an historical overview.” Ochsner journal vol. 5,3 (2003): 6-10. https://pmc.ncbi.nlm.nih.gov/articles/PMC3111838/ Smithburn, K.C. et al. “A Neurotropic Virus Isolated from the Blood of a Native of Uganda.” The American Journal of Tropical Medicine and Hygiene. Volume s1-20: Issue 4. 1940. Steere, Allen C et al. “The emergence of Lyme disease.” The Journal of clinical investigation vol. 113,8 (2004): 1093-101. doi:10.1172/JCI21681 Steere, Allen C. et al. “Historical Perspectives.” Zbl. Bakt. Hyg. A 263, 3-6 (1986 ). https://pdf.sciencedirectassets.com/281837/1-s2.0-S0176672486X80912/1-s2.0-S0176672486800931/main.pdf World Health Organization. “West Nile Virus.” 10/3/2017. https://www.who.int/news-room/fact-sheets/detail/west-nile-virus Xiao, Y., Beare, P.A., Best, S.M. et al. Genetic sequencing of a 1944 Rocky Mountain spotted fever vaccine. Sci Rep 13, 4687 (2023). https://doi.org/10.1038/s41598-023-31894-0 See omnystudio.com/listener for privacy information.

In this fun-filled listener Q&A, our hosts tackle your questions — covering everything from navigating the first week post-show, to genetic advantages in athletes, to practical tips like how competitors achieve that tight waistline on stage. Enjoy this episode and stay tuned for Part 2!

Liz covers health and genetic tests, creatine, enlarged pores, menstrual symptoms, and liver health for this Q&A podcast.Abigail asks for recommendations on health and genetic tests, while Terina has a question on collagen and creatine for aches and pains.Liz answers an anonymous question on dealing with enlarged pores on ageing skin, and another on how to best support liver health.She also helps Amelia deal with her debilitating menstrual symptoms.Links mentioned in the episode:Medichecks, Thriva, Randox Health, Hum2n - Health testsSkip the queue at Healf Zone through this exclusive linkLifeCode GXNatureDoc Newson Health ClinicEverything you need to know about the pill (but were too afraid to ask) by Kate MuirThe pill, HRT and medical gaslighting – with Kate MuirPain management for migraine – with Dr Katy MunroThe National Migraine CentreA Better Second Half by Liz EarleHave a question for Liz? Send a WhatsApp message or voicenote to 07518 471846, or email us at podcast@lizearlewellbeing.com for the chance to be featured on the showPlease note, on some occasions, we earn revenue if you click the links and buy the products, but we never allow this to bias our coverage and always honestly review. For more information please read our Affiliate Policy. Hosted on Acast. See acast.com/privacy for more information.

Send comments and feedbackSomatic genetic epilepsies arise from mutations that occur early in fetal development. They are usually only detectable by genetic sequencing of tissue. For these epilepsies, the timing of the mutation is key: For example, research has shown that focal cortical dysplasia type IIB and hemimegaloencephaly are genetically the same disease, but arise from somatic mutations at different developmental time points. This relatively new area of research is discussed by Dr. Alina Ivaniuk and Dr. Christian Bosselmann.Resources:Analysis of 1,386 epileptogenic brain lesions reveals association with DYRK1A and EGFR (Nature Communications 2024 - C. Bosselmann et al.)Neocortical development and epilepsy: Insights from focal cortical dysplasia and brain tumours (The Lancet Neurology 2021 - I. Blumcke et al.)Contribution of somatic Ras/Raf/Mitogen-activated protein kinase variants in the hippocampus in drug-resistant mesial temporal lobe epilepsy (JAMA Neurology 2023 - S. Khoshkhoo et al.)Somatic mosaicism and neurodevelopmental disease (Nature Neuroscience 2018 - AM D'Gama and CA Walsh)BRAF somatic mutation contributes to intrinsic epileptogenicity in pediatric brain tumors (Nature Medicine 2018 - HY Koh et al.)SLC35A2 loss-of-function variants affect glycomic signatures, neuronal fate and network dynamics (Brain 2025 - D Lai et al.)Precise detection of low-level somatic mutation in resected epilepsy brain tissue (Acta Neuropathologica 2019 - NS Sim et al.)Toward a better definition of focal cortical dysplasia: An iterative histopathological and genetic agreement trial (Epilepsia 2021 - I Blumcke et al.)Seizure outcome and use of antiepileptic drugs after epilepsy surgery according to histopathological diagnosis: A retrospective multicentre cohort study (The Lancet Neurology 2020 - HJ Lamberink et al.) Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice.Let us know how we're doing: podcast@ilae.org.The International League Against Epilepsy is the world's preeminent association of health professionals and scientists, working toward a world where no person's life is limited by epilepsy. Visit us on Facebook, Instagram, and LinkedIn.

Guest: Sergio Baranzini, PhD In a landmark study involving over 10,000 patients, the International MS Genetics Consortium (IMSGC) has identified the first genetic variant associated with disease severity in multiple sclerosis (MS). Dr. Sergio Baranzini, a Distinguished Professor of Neurology at the University of California, San Francisco Weill Institute for Neurosciences, explains what's next in researching this variant and working towards effective treatments. Dr. Baranzini also spoke on this topic at the 2025 Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS).

Guest: Sergio Baranzini, PhD In a landmark study involving over 10,000 patients, the International MS Genetics Consortium (IMSGC) has identified the first genetic variant associated with disease severity in multiple sclerosis (MS). Dr. Sergio Baranzini, a Distinguished Professor of Neurology at the University of California, San Francisco Weill Institute for Neurosciences, explains what's next in researching this variant and working towards effective treatments. Dr. Baranzini also spoke on this topic at the 2025 Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS).

Send us a textGenetic & environmental factors that affect brain health, including why people age faster in outer space. (Note: technical difficulties affected the audio quality of this recording somewhat)Episode Summary: Dr. Jacob Raber explains how apolipoproteins, particularly ApoE, influence brain health and disease risk; their role in cholesterol metabolism, Alzheimer's disease, and responses to environmental stressors like radiation and viral infections; interplay between genetics, diet, and lifestyle factors, highlighting how these affect cognitive function and resilience to stress; research into space radiation, the gut-brain axis, and potential interventions for neurodegenerative diseases.About the guest: Jacob Raber, PhD, is a neuroscientist at Oregon Health & Science University (OHSU) in Portland, where he leads a lab studying genetic and environmental influences on brain health, particularly using mouse models with human genes.Discussion Points:Apolipoproteins (ApoE2, E3, E4) are proteins involved in cholesterol and lipid metabolism in the brain, with ApoE4 increasing risks for Alzheimer's and cardiovascular disease.ApoE4 carriers may face higher risks for cognitive decline but could have advantages in specific contexts, like fertility or certain infections.Environmental stressors, such as space radiation and viral infections like West Nile, can exacerbate oxidative stress, impacting brain health.The gut microbiome influences brain function indirectly via the gut-liver-brain axis, with ongoing studies exploring its role in Alzheimer's and traumatic brain injury.Lifestyle factors like diet, exercise, and sleep are critical for brain health, potentially mitigating genetic risks like ApoE4.Statins, commonly used for cholesterol management, may impair learning in healthy animals, suggesting context-dependent effects.Research into space radiation reveals potential therapeutic applications, such as using heavy ion radiation for cancer treatment.Genetic variations, including ethnicity and sex, influence ApoE-related disease risks, with women and certain populations showing higher Alzheimer's susceptibility.Chronic low-level stressors, like air pollution, may pose greater risks to brain health than acute exposures due to insufficient activation of protective mechanisms.Related content:M&M 165: PUFAs in Brain Health & Disease, Dietary Fats, Brain Lipids, Nutrition | Richard Bazinet*Not medical adviceSupport the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

On this episode of the podcast, Alex Becerra is joined by SAFE's Senior Design and Communications Specialist, Susan Burns to tackle the topic of Financial Avoidance. Together they discuss Susan's featured articles in Comstock's Magazine, the importance of understanding your relationship with money, and strategies for leveraging your unique personal qualities to keep your finances in check. They also provide useful insights for being a positive money role model and helping the young people in your life as they learn to navigate their own financial wants, needs, and goals. Tune in today, because learning and demonstrating smart money behaviors to inspire the young people in your life as they build financial freedom… just makes Perfect Cents! To check out the resources highlighted in this episode visit the links below. Read Susan's latest article in Comstock's Magazine: "How to Avoid Passing Financial Fears to Kids" Read Susan's first article in Comstock's Magazine: "Are You a Financial Avoidant?" To register for an upcoming Financial Wellness webinar visit: https://www.safecu.org/community/events To read the latest edition of SAFE's Beyond Everyday Banking blog visit: https://blog.safecu.org/ To learn more about SAFE Credit Union products and services visit: https://www.safecu.org/  To contact the podcast team, email Podcast@safecu.org

Genetic genealogy is a field that combines traditional genealogy research with modern DNA testing techniques to trace familial relationships and ancestry through genetic information. It involves analyzing an individual's DNA to uncover their genetic heritage, connect with distant relatives, and map out family trees. This approach has gained significant popularity due to advancements in DNA sequencing technology, particularly in the form of direct-to-consumer DNA testing kits.Here's how genetic genealogy works and how it's used by investigators:DNA Testing: Individuals interested in exploring their genetic heritage and family history can submit their DNA samples through services provided by companies like AncestryDNA, 23andMe, and MyHeritageDNA. These companies analyze specific segments of the submitted DNA to identify genetic markers that are common among different populations and individuals.Genetic Markers: Certain sections of the DNA, particularly those found in the Y chromosome (passed from father to son) and the mitochondrial DNA (passed from mother to all offspring), contain genetic markers that can be used to identify ancestral lineages. Autosomal DNA, which is inherited from both parents, is also examined to find matches with other individuals in the testing company's database.Matching and Comparison: Testing companies compare an individual's genetic markers with those of other users in their databases. If two individuals share a significant amount of genetic material, they are considered genetic matches. The more segments of DNA they share, the closer their relationship is likely to be.Building Family Trees: Genetic genealogy involves constructing family trees using a combination of traditional genealogical research and the information gained from DNA matches. By connecting with other users who share segments of DNA, individuals can extend their family trees and discover new branches of their lineage.Identifying Common Ancestors: As more people participate in DNA testing, the chances of finding common ancestors increase. Overlapping segments of shared DNA can help identify specific ancestors or ancestral groups that are shared among related individuals.Forensic and Investigative Applications: Genetic genealogy has also found applications in criminal investigations. Law enforcement agencies have used DNA databases to identify unknown perpetrators of crimes like murder and sexual assault. In cases where traditional investigative methods have been unsuccessful, investigators can upload DNA profiles from crime scenes to genealogy databases and identify potential relatives of the suspect based on shared genetic markers.Building Family Trees for Identification: Once potential relatives of the suspect are identified, investigators work to build family trees using genealogical records, such as birth certificates, marriage records, and obituaries. By tracing the shared ancestry of these relatives, law enforcement can narrow down the list of potential suspects to a smaller pool.Narrowing Down Suspects: Investigative genetic genealogy can help law enforcement focus on specific individuals who fit the profile of the unknown suspect based on age, location, and other relevant factors. This process has led to the successful identification and capture of suspects in several high-profile cases.Bryan Kohberger was tracked down by authorities using genealogy according to sources. While the process is not even admissable in court, it is an important tool for investigators who are trying to solve complex cases.In this episode, we hear from one of the industry leaders in the field of genealogy who is discussing how the process works and what goes into an operation such as this.(commercial at 12:11)to contact me:bobbycapucci@protonmail.comsource:How Idaho cops used genetic genealogy to trace suspect Bryan Kohberger's distant relatives | Daily Mail OnlineBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-moscow-murders-and-more--5852883/support.

You must've wondered if there's a connection between sexlessness and genetics. A 2025 scientific study was done. Listen now for those results.Homesite

How can working with our genes help us feel better, physically and mentally?  What can our genes tell us about treating our mental health? What is MTHFR? In this episode of the Ancient Health Podcast, Dr. Motley and Dr. J Dunn explore the intricate world of methylation, detoxification, and genetics. Learn about the implications of specific genes on mental health, autoimmune conditions, and the power of vitamins and nutrients in your overall health. Understanding your unique biological pathways can empower you on your health journey! Click here for a wholistic methylation chart: https://wholisticmethylation.com/product-category/methylation-pathways/ Want more of the Ancient Health Podcast? Check out Doctor Motley's YouTube channel! ------  Follow Doctor Motley  Instagram Facebook Website Follow Dr. J https://www.youtube.com/@DrJADunn https://www.instagram.com/myhappygenes/?hl=fr www.wholisticmethylation.com www.myhappygenes.com ------   *If you want to work with Dr. Motley virtually, you can book a discovery call with his team here: https://drmotleyconsulting.com/schedule-1333-7607 * Do you have a ton more in-depth questions for Doctor Motley? Are you a health coach looking for more valuable resources and wisdom? Join his membership for modules full of his expertise and clinical wisdom on so many health issues, plus bring all your questions to his weekly lives! Explore it free for 15 days at https://www.doctormotley.com/15 * This episode is brought to you by Zona Plus. If you're looking for a safe, easy way to improve your heart health, check out zona.com and use code DRMOTLEY for $100 off the Zona Plus device! 

Dad. Bio dad. Genetic father. Father. After people connect with their newfound biological fathers, they often struggle with what to call them. And what about the dads we grew up with? Raised dad. Step-dad. Birth-certificate dad. Then there's the well-meaning but perpetually frustrating phrase, “your dad is still your dad.” Love that one.Many of us do continue calling the dads we grew up with dad. But what if your relationship with your raised father is traumatic? What if you were always distant, and there's no real love lost after uncovering a DNA surprise?In this week's episode, Luisa shares a name I hadn't heard yet on the show - Fake Dad. She shares how she uncovered her DNA surprise and the impact that it had on her relationship with her parents, as well as the biological father she was able to identify. He's called “New Dad,” by the way.A quick warning before this episode begins - there is mention of childhood sexual abuse during our conversation.Thank you for sharing your story, Luisa.Support the show.

Genetic research reveals a “rescue” gene in fruit flies that allows cross-species offspring to survive but results in sterility or weakened health. This gene poses a problem for evolutionary theory, as it offers no clear benefit for survival or reproduction. Such discoveries highlight God's design in maintaining distinct biological kinds. To support this ministry financially, visit: https://www.oneplace.com/donate/1232/29

As always you can find Christian on Twitter/Instagram @thechrisespinal Josh @jdcole_37 and Brian @bdotesp! follow the show on Twitter/Instagram @newjumpcity.   Check out Brian's Twitch Stream here!   Our theme song is by @drum_fu.

In this episode, we sit down with Dr. Tyler Panzner, a PhD scientist specializing in genetic health optimization, to discuss the most common mistakes people make with supplements. He emphasizes the importance of integrating both genetic data and blood work to create personalized wellness strategies, noting that while genetics reveal potential vulnerabilities, lifestyle and epigenetics determine how those genes express. Dr. Panzner also highlights the significance of methylation genes (like COMT), which impact neurotransmitters and detoxification, touches on the role of GLP-1s, as well as how psychedelics can be helpful tools. Overall, the conversation reinforces the value of precision health—leveraging genetic insights alongside lifestyle factors to make smarter, safer choices in supplementation.Dr. Tyler Panzner is a Ph.D. scientist with a deep background in pharmacology, cancer, neuroscience, and inflammation research. His passion for how different substances affect the body has been lifelong, but about seven years ago, he found his true calling in genetics and personalized medicine. Since then, he's been on a mission to create personalized vitamin, supplement, and lifestyle protocols tailored to each individual's unique biology.His approach is all about understanding what your cells truly need and uncovering which vitamins, supplements, or foods might not be a good match for your genetic makeup. He firmly believes that by aligning your habits with your genes, not only can you feel your best every day, but you can also lower your risk for chronic diseases in the long run. His practice focuses on genetically optimizing health, helping people unlock their body's full potential to truly thrive.Dr. Panzner sees a massive lack in supplement education across all sectors of healthcare, which shows up as unnecessary suffering as people feel worse due to the wrong supplement recommendations. He is driven to educate both practitioners for their practice and consumers in the supplement aisle of the store so they can make more informed decisions regarding their or their patient's supplementation strategies.SHOW NOTES:0:39 Welcome to the podcast!3:31 Dr. Tyler Panzner's Bio4:03 Welcome him to the show!5:05 This biggest mistake with supplementation9:31 Iron chelation & anemia12:35 CBD & Serotonin blockers15:51 GLP-1s: the good & bad24:25 Genetics vs lifestyle26:37 Cross-referencing with lab work 31:11 Histamine issues35:59 *ALIGN MAT*37:36 Methylation genes44:30 MTHFR52:46 Genetic testing57:17 Alzheimer's & APOE1:00:58 Psychedelics & genetics1:11:58 Natural ways to raise BDNF1:12:41 His finale piece of advice1:15:34 Where to find him1:16:16 Thanks for tuning in!RESOURCES:https://drtylerpanzner.com/InstagramFacebookLinkedInYouTubeTikTokAlign Mat - $250 off with code: BIOHACKERBABESEp 291: Align Mat with Alyssa & MikeSupport this podcast at — https://redcircle.com/biohacker-babes-podcast/donationsAdvertising Inquiries: https://redcircle.com/brands

Thousands of you listen to the podcast every week, but we've come to realise many of you don't know exactly what we do here at neXtgen Agri. In this episode, Mark, our host and CEO, takes to the mic and chats about all things neXtgen Agri and the services we provide to farmers across the globe. He shares how “farming in our hearts, science in our heads” drives everything we do.From helping farmers lift genetic gain to building tools that make breeding decisions clearer and faster, Ferg goes through the work that keeps our team busy. We're out in the yards and around kitchen tables across Australia and New Zealand, as well as in meetings and boardrooms for multiple industry bodies, helping provide the knowledge transfer bridge between farmers and scientists.If you have ever wondered what neXtgen Agri is really about, this is the episode that explains it all.Head Shepherd is brought to you by neXtgen Agri International Limited. We help livestock farmers get the most out of the genetics they farm with. Get in touch with us if you would like to hear more about how we can help you do what you do best: info@nextgenagri.com.Thanks to our sponsors at MSD Animal Health and Allflex, and Heiniger Australia and New Zealand. Please consider them when making product choices, as they are instrumental in enabling us to bring you this podcast each week.Check out Heiniger's product range HERECheck out the MSD range HERECheck out Allflex products HERE

In this episode, Dr Tsen Vei Lim speaks to Dr Wei Deng, an assistant professor from McMaster University and St Joseph's Healthcare Hamilton, Canada. The interview covers the research article Wei led examining externalising as a common genetic influence for a broad spectrum of substance use and behavioural conditions using a large UK longitudinal dataset.‘Externalising' is a type of outward-directed behavioural expression, such as risky substance use, aggression, and hyperactivity. ‘Polygenic risk scores' are numbers that estimate a person's inherited risk for a disease, trait, or condition (in this case, addiction) based on the presence of many genetic variants. · Why studying genetics is important for addiction [01:12]· How we study the genetics of addiction [01:57]· Polygenic risk scores and their importance in addiction [3:49]· The origin of Wei's research questions [05:32]· The headline findings of the paper [08:06]· How the findings affect the way we currently think about addiction [09:22]· Common genetic components shared between behavioral and substances addictions [11:11]· The importance of the environment in the genetic risks of addiction [13:15]· How the findings can contribute to clinical practice [13:37]· How big data and artificial intelligence (AI) can help us understand addiction [14:42]· The exploration of whether genetic factors are the root cause of addiction [18:06]About Tsen Vei Lim: Dr Lim is an academic fellow supported by the Society for the Study of Addiction, currently based at the Department of Psychiatry at the University of Cambridge. His research integrates computational modelling, experimental psychology, and neuroimaging to understand the neuropsychological basis of addictive behaviours. He holds a PhD in Psychiatry from the University of Cambridge (UK) and a BSc in Psychology from the University of Bath (UK).About Wei Q Deng: Dr Deng is a statistical scientist who investigates how genes, brain function, and environment shape long-term health risks. Her research focuses on delay discounting and related self-regulation processes that influence decisions about health, substance use, and long-term planning. She studies how these traits contribute to addiction and chronic conditions like diabetes and heart disease. Using large-scale data and molecular tools, she uncovers why some people are more vulnerable and how those risks can be reduced. Based at McMaster University and St Joseph's Healthcare Hamilton, she leads interdisciplinary projects bridging genomics, behavior, and public health.Original article: Externalizing as a common genetic influence for a broad spectrum of substance use and behavioural conditions: a development perspective from the Avon Longitudinal Study of Parents and Children. https://doi.org/10.1111/add.70163The opinions expressed in this podcast reflect the views of the host and interviewees and do not necessarily represent the opinions or official positions of the SSA or Addiction journal.The SSA does not endorse or guarantee the accuracy of the information in external sources or links and accepts no responsibility or liability for any consequences arising from the use of such information. Hosted on Acast. See acast.com/privacy for more information.

Throughout the years, we've always been scared of Breast Cancer and the possession of the BRCA gene which may indicate its presence - but did you know it's one of the more curable forms of cancer with a 99% survival rate when detected early?This is the journey Beyond BRCA—where we explore not just the mutation, but the terrain it travels through. Where we ask: What does it mean to fly with purpose, even when the skies are uncertain? And how can we equip the next generation of with the tools to navigate their own health?Today we highlight how knowing your BRCA status isn't the destination but the beginning of taking ahold of your health. Here are the highlights of today's episode:The Limits of BRCAHow BRCA1/2 became the most recognized breast cancer genesWhy most breast cancers are not BRCA-relatedEmotional impact of isolated genetic results without terrain context Recent Statistics & Relevant Data Other Genetic Pathways Detoxification genes: GST, CYP1A1, CYP1B1, COMTHormone metabolism, oxidative stress, inflammationFunctional genomics Genes Are Not Destiny Genetic predisposition vs. tipping pointsReal-world examples of risk reductionEpigenetics Tools for Prevention & Precision HealthDNA360 Test metabolism, DNA repairBreast360 TestGrail Liquid BiopsyActionable Strategies ______________________________________________________Keep yourself up to date on The DNA Talks Podcast! Follow our socials below:The DNA Talks Podcast Instagram: https://www.instagram.com/dnatalkspodcast/______________________________________________________Music: Inspiring Motivational Background by Stock-Waveshttps://www.stock-waves.com/https://protunes.net/Video Link:  https://www.youtube.com/watch?v=pbwVDTn-I0o&list=PLQtpqy3zeTGB7V5lkhkfBVaiZyrysv_fG&index=5______________________________________________________Music: Peaceful Corporate by Stock-Waveshttps://protunes.net/Video Link:  https://www.youtube.com/watch?v=I34bTKW8ud0&list=PLQtpqy3zeTGB7V5lkhkfBVaiZyrysv_fGMedical Disclaimer: The information provided in this communication is for general informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read here. If you think you may have a medical emergency, call your doctor or 911 immediately.

Welcome to Mind The Kids, hosted by Mark Tebbs. In this episode, Mark sits down with Dr. Charlotte Viktorsson, a behavioural genetics researcher at Uppsala University, to explore the genetic and environmental influences on infant sleep and crying. Drawing on findings from a major study involving nearly 1,000 sets of Swedish twins, they discuss how much of a baby's crying is down to genetics and why sleep quality often depends on home routines and environment. If you're a parent in the thick of sleepless nights or frequent tears, this episode offers both reassurance and fresh insight. Dr. Viktorsson explains why some babies simply cry more than others—even in the best of circumstances—and shares practical advice for supporting your child's wellbeing in those challenging early months. Tune in for an enlightening conversation that brings clarity and comfort to anyone caring for young children. Based on the findings of ‘Genetic and environmental influences on sleep quality, ability to settle, and crying duration in 2- and 5-month-old infants: A longitudinal twin study' Charlotte Viktorsson, Ashraf Yahia, Mark J. Taylor, Angelica Ronald, Kristiina Tammimies, Terje Falck-Ytter. https://doi.org/10.1002/jcv2.70023

This episode of Kiwi Birth Tales is proudly brought to you by Your Birth Project. In this episode of Kiwi Birth Tales, I speak to Abby. Some of the topics we cover:Spotting before a positive pregnancy test Testing in pregnancy Wanting an unmedicated birth Baby breech presentation at 37 weeksPracticed spinning babies daily and she turned Didn't find out sex during pregnancy Spontaneous labour Losing large amount of water / fluid after waters broke Fast labour Immediate latch after birth Lots of mucus coming from Sadies nose post birth Transferred to hospital for size (2.5kg, 47cm and small head circumference) Struggled with weight gainObsessive tracking of feeds Re-admission to the hospital Heart murmur Referral to paediatrician Blood tests - DiGeorge Syndrome (22Q.11) Your Birth Project Online Hypnobirthing Coursehttps://www.fertilityassociates.co.nz/book-a-free-nurse-consultPlease seek support for any mental health concerns, some helpful links are below:Mental Health in PregnancyPerinatal Depression and Anxiety Aotearoa Plunket - Dads Mental HealthLittle Shadow - Private Counselling NZFind me @kiwibirthtales and @yourbirthproject Hosted on Acast. See acast.com/privacy for more information.

Topics: (00:00:00) - Intro(00:03:26) - Marathon misadventures(00:06:15) - The failed acquisition(00:13:47) - Lessons from the deal(00:29:31) - The future of retail(00:33:44) - Empathy for founders(00:35:23) - The grind of capitalism(00:35:37) - Challenges for young founders(00:36:10) - The importance of peer support(00:37:17) - Scaling and growth pains(00:37:42) - Exciting new ventures(00:38:20) - Genetic engineering innovations(00:43:40) - Revolutionizing air freight with airships(00:49:56) - Terraform Industries: Energy independence(01:02:17) - Innovative warehouse automation(01:05:25) - Mining industry disruption(01:09:45) - Conclusion and future outlook Links: Join us in Rolling Fun! Hear our other Rolling Fun eps! To support the costs of producing this podcast:  >> Buy a copy of the Navalmanack: www.navalmanack.com/  >> Buy a copy of The Anthology of Balaji: https://balajianthology.com/ >> Sign up for my online course and community about building your Personal Leverage: https://www.ejorgenson.com/leverage  >> Invest in early-stage companies alongside Eric and his partners at Rolling Fun: https://angel.co/v/back/rolling-fun >> Join the free weekly email list at ejorgenson.com/newsletter >> Text the podcast to a friend >> Or at least give the podcast a positive review to help us reach new listeners! We discuss: Why personal networks matter most when raising money quickly for big deals New investments in companies building genetically engineered animals, advanced airships, and solar-powered synthetic natural gas How real operational experience shapes the way we invest and support founders The balance of optimism and realism required to keep taking shots in business Quotes from Al: “Just keep taking the shots. A shooter's gotta shoot.” “Sometimes you take the shot, do everything right, and the ball still doesn't go in.” “There's no classy way to advertise, ‘Hey, your favorite store died—but we're a good rebound.'” “Capitalism is an unforgiving mistress.” “Personal relationships were the most valuable asset I had in that deal.” “Sometimes I think, ‘I should be inventing Facebook 2,' but here I am—investing in fabric.” “I've never worked on a deal that hard. It should have gone my way… and didn't.” “You wake up the next morning and it didn't happen, but I still have a great family, and my business is still running.” “It's hard until it isn't—and even when it isn't, it's still freaking hard.” Quotes from Bo: “We're actual operators—curious about what's possible with technology—and that makes us better investors.” “On a Thursday, ‘This deal is happening.' Then Tuesday? ‘It's over. We lost.'” “We have a unique amount of empathy for founders—because we know how hard this shit is.” “If you can pull it off, it's transformational. And that's awesome.” (on Airship) “A blimp is not a quadcopter to carry Al's big ass—it's an elegant, slow-moving blimp.” “There's a lot of industries still doing 90/10 in-store sales. That blew my mind.” “It's a real ‘software is eating the world' moment—but finally arriving at the mining industry.” “When you're building something that matters, you're playing the long game—even if the outcome is uncertain.” “The people who make glow-in-the-dark fish… now they're building unicorns. And yeah, it's gonna happen.”

In this conversation, Dr. Nick Wilson and Leah Wilson, J.D. explore the misconceptions surrounding genetic determinism and the impact of environmental factors on health. They discuss the nocebo effect, the influence of family health patterns, and the role of epigenetics in determining health outcomes. The conversation emphasizes the importance of nutrition and lifestyle choices in shaping genetic expression and encourages listeners to take control of their health narratives. In this thought-provoking episode, Dr. Nick and Leah Wilson explore the complex and often misunderstood topic of birth control. With honesty and compassion, they break down common misconceptions surrounding hormonal contraceptives: how they work, what they do to a woman's body, and the long-term impact they can have on health, fertility, and even relationships. Topics Covered: The nocebo effect can cause real harm to health. Family habits, not just genes, influence disease. Epigenetics shows that environment affects gene expression. Nutrition can turn genes on and off. You can change your health in as little as 90 days. Your body is constantly renewing itself. You are not a victim of your genes. Empowerment comes from understanding your health. 

In this episode, Dr. Scott A. Johnson discusses the rising challenges of fertility and infertility with Dr. Aumatma Simmons, a leading expert in holistic fertility care. They explore the statistics surrounding infertility, the genetic and environmental factors influencing fertility, and the importance of nutrition and lifestyle modifications. Dr. Simmons emphasizes the role of methylation and the impact of toxins on reproductive health, while providing practical advice for couples trying to conceive. The conversation highlights the need for early intervention and personalized approaches to fertility care.Connect with Dr. Scott A.Johnsonauthorscott.comFacebook Instagram YouTube Links to purchase booksConnect with Dr. SimmonsConnectwith Dr. Aumatma on InstagramCheck out Dr. Aumatma on the TEDx Stage!HolisticFertilityInstitute.com| madrefertility.comTakeawaysInfertility affects 10-15% of couples worldwide.Genetic mutations can significantly influence fertilityoutcomes.Methylation issues are increasingly recognized in fertilitydiscussions.Diet and lifestyle are crucial for preconception health.Environmental toxins, especially plastics, impact fertility.Sleep quality is foundational for reproductive health.Early intervention can prevent long-term fertility issues.Holistic approaches can address root causes of infertility.Personalized nutrition is key to optimizing fertility.Healthy babies start with healthy parents.Chapters00:00 Introduction to FertilityChallenges03:28 Understanding InfertilityStatistics05:54 The Role of Genetics inFertility08:34 Methylation and Its Impacton Conception11:13 Nutritional Foundations forFertility13:43 Essential Nutrients forPreconception and Pregnancy16:26 Diet and LifestyleModifications for Improved Fertility22:11 The Importance of Sleep inFertility26:45 Understanding Fertility as aMultifaceted Issue31:51 The Impact of EnvironmentalToxins on Fertility39:35 Guidance for Couples FacingFertility Challenges43:05 Short Outro.m4v

Host Matt chats with American genetic counsellor Dr Lisa Schwartz about the evolving professional identity of genetic counsellors, the role of networking and qualitative research (including authors' positionality), and how clinical training translates into lab, policy and education roles. They also swap stories about travel, outdoor winery concerts, Stevie Nicks, their dogs, and advances in genetics such as Duchenne research, while discussing how training and definitions may need to change as the profession grows.

STgenetics® Canada team members join us to reflect on the 2025 August Genetic Evaluations now that the dust has settled. Mike Barnum and Ryan Corrigan share what stood out to them, the power of proven maternal lines and the impact of indexes like Eco$ and RCI. Additionally, we hear about newly released sires like BEATBOX, BARITONE and more along with how Farmfit® has been received and improved for the market.00:00 Introduction and Welcome00:33 Highlights of the August 2025 Genetic Evaluations01:37 Importance of Proof Runs for Dairy Producers03:03 Third Generation TPI Sire Achievement04:16 Canadian Bulls and Their Impact08:51 Newly Released Bulls11:47 Understanding Balance in Dairy Breeding12:51 Eco$ Index: Enhancing Dairy Profitability15:15 Robotic Count Index: A Leading Selection Tool17:52 Farmfit® and Other Technological Advancements20:39 Future Breakthroughs in Dairy Genetics22:55 Final Thoughts and Conclusion

Some conditions hide in your genes, without any symptoms. One of these conditions is genetic arrhythmogenic cardiomyopathy, an inherited condition that can lead to sudden cardiac arrest — even if you feel completely fine.In this episode, Sarah and Leslie talk about their shared diagnosis of FLNC cardiomyopathy — from how this gene mutation affects the function of the heart to how they're managing this rare condition. You'll hear how Leslie's ICD has saved her life more than once, how it feels to be shocked back to life, and the resilience that's helped them move forward.This is a raw, real, emotional episode about living with a genetic heart condition. Tune in to learn the signs to watch for, when to get tested, and where to find support!Topics discussed in this episode:What is genetic arrhythmogenic cardiomyopathy?How FLNC-AC differs from other cardiomyopathiesCommon symptoms and some people are diagnosed too lateTreatment and lifestyle managementHow Sarah and Leslie finally got diagnosedLeslie's first cardiac arrest and its impactHow Sarah is processing her diagnosisWhat it feels like to be shocked by your ICDTypes of ICDs: transvenous, SICD, and EV-ICDMental and emotional recovery post-cardiac arrestThe WomenHeart organizationFind support or volunteer with WomenHeart:https://www.womenheart.org/Mentioned in this episode:Voices in NursingCheck out the Voices in Nursing Podcast here: https://www.aacn.org/education/podcast-series/voices-in-nursingCONNECT

Sponsored By: → Cornbread Hemp | For an exclusive offer go to cornbreadhemp.com/drg and use promo code DRG for 30% OFF your first order! Sign up for our newsletter! https://drchristiangonzalez.com/newsletter/ Cancer has been growing in your body for 8-10 years before you feel anything. While conventional doctors wait for symptoms—lumps, pain, bleeding—you're losing nearly a decade of prevention time. Dr. Leigh Erin Connealy, who runs one of America's largest integrative cancer centers, reveals the shocking truth: less than 1% of cancers are actually genetic. The rest are completely preventable, but medical school teaches disease management, not prevention protocols. She's developed blood tests that catch cancer before it becomes cancer, discovered why your emotions literally create disease in your body, and uses protocols to reverse what conventional medicine calls "incurable." Cancer rates are exploding in young people—this isn't wellness talk, it's life-or-death information that could save you or someone you love. In this episode, you'll learn: • Cancer's hidden 8-10 year timeline: from first abnormal cell to detectable tumor—why early intervention during this window can prevent cancer entirely, not just treat it after diagnosis • The real cancer causes: less than 1% genetic, 99% environmental factors including chronic stress, toxin exposure, and unresolved emotional trauma that keeps you in survival mode • Liquid biopsy breakthroughs: blood tests detecting circulating tumor cells years before imaging shows anything—90% accuracy in identifying cancer development before symptoms appear • Why conventional treatment fails: surgery, chemo, and radiation treat symptoms but ignore the toxic terrain that allowed cancer to develop in the first place • The emotional cancer connection: how chronic unresolved stress suppresses immune function and creates the acidic environment cancer thrives in—plus the device that identifies emotional conflicts in minutes • Advanced prevention protocols: comprehensive blood work detecting hormonal imbalances, heavy metals, and inflammatory markers that predict cancer risk years in advance • Low-dose chemotherapy revolution: using 10% conventional doses with insulin targeting and immediate detox support to maximize effectiveness while minimizing damage • The fungal theory of cancer: why medications like fenbendazole and ivermectin show anti-cancer properties and how to use them safely with proper liver protection • Personalized nutrition strategies: why there's no one-size-fits-all cancer diet and how to determine whether keto, plant-based, or other approaches work for your specific situation • Energy medicine integration: how frequency therapy, red light treatment, and cellular voltage optimization support healing at the deepest level alongside conventional treatments Timestamps: 0:00 - Introduction 2:31 - How Early Can Cancer Be Detected? 7:25 - The Biggest Truth About Cancer: 100% Preventable, Not Genetic 12:01 - Hormones & The Great Poisoning: Environmental Toxins Impact 17:45 - What Conventional Cancer Treatment Is Missing 27:08 - Integrative Cancer Protocols 32:04 - The Role of Emotions in Cancer 40:02 - Creating Healing Environments 45:17 - Repurposed Drugs: Fenbendazole, Ivermectin & Cancer Treatment 49:05 - Best Diets for Cancer 56:33 - Liquid Biopsies: Early Detection Technology & Prevention Focus

(00:00-14:00) Who do you like more, Harry Connick Jr or Gabe's new snack? Happy birthday to Jeff Burkett! Jackson liking guys with facial hair is a jealousy thing. A visually appalling genetic mistake. Does Wally's have house shoes? Following through on the Nolan Arenado audio tease. Nolan Arenado interviewed in Springfield ahead of a rehab start as he reflects on the year. Beards. Give me buzz cut Pitt.(14:08-27:37) Happy 48th Birthday to Ludacris. Don't get Jackson started on Crash. The Border War will be put on hold after next year's rematch in Lawrence. Audio of Lance Leipold talking about needing to play the border war “as often as they can.” Should we do a remote from Provo? A nasally cuckold.(27:47-52:41) So What'd Your Grandma Think featuring Dan Campbell of the Detroit Lions. People are wondering. Bonnie Raitt. Mt. Rushmore of Julia Roberts films. Late 80's loving. Biff is on the line and he's got the top chicken joints in St. Louis. Chicken wings with girls in the background without clothes on. Isn't it nice to get a double Mount Rushmore? How small are Ky's hands? Jackson putting together a Dream Team for the Lemmings Open.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Defenders: Doctrine of Man (Part 17): Genetic Challenges to Adam and Eve

Ataxia is a neurologic symptom that refers to incoordination of voluntary movement, typically causing gait dysfunction and imbalance. Genetic testing and counseling can be used to identify the type of ataxia and to assess the risk for unaffected family members. In this episode, Katie Grouse, MD, FAAN, speaks with Theresa A. Zesiewicz, MD, FAAN, author of the article “Ataxia” in the Continuum® August 2025 Movement Disorders issue. Dr. Grouse is a Continuum® Audio interviewer and a clinical assistant professor at the University of California San Francisco in San Francisco, California. Dr. Zesiewicz is a professor of neurology and director at the University of South Florida Ataxia Research Center, and the medical director at the University of South Florida Movement Disorders Neuromodulation Center at the University of South Florida and at the James A. Haley Veteran's Hospital in Tampa, Florida. Additional Resources Read the article: Ataxia Subscribe to Continuum®: shop.lww.com/Continuum Earn CME (available only to AAN members): continpub.com/AudioCME Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the American Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Full episode transcript available here Dr Jones: This is Dr Lyell Jones, Editor-in-Chief of Continuum. Thank you for listening to Continuum Audio. Be sure to visit the links in the episode notes for information about earning CME, subscribing to the journal, and exclusive access to interviews not featured on the podcast. Dr Grouse: This is Dr Katie Grouse. Today I'm interviewing Dr Theresa Zesiewicz about her article on ataxia, which appears in the August 2025 Continuum issue on movement disorders. Welcome to the podcast, and please introduce yourself to our audience.  Dr Zesiewicz: Well, thank you, Dr Grouse. I'm Dr Theresa Zesiewicz, otherwise known as Dr Z, and I'm happy to be here. Dr Grouse: I have to say, I really enjoyed reading your article. It was a really great refresher for myself as a general neurologist on the topic of ataxia and a really great reminder on a great framework to approach diagnosis and management. But I wanted to start off by asking what you feel is the key message that you hope our listeners will take away from reading your article. Dr Zesiewicz: Yes, so, thanks. I think one of the key messages is that there has been an explosion and renaissance of genetic testing in the past 10 years that has really revolutionized the field of ataxia and has made diagnosis easier for us, more manageable, and hopefully will lead to treatments in the future. So, I think that's a major step forward for our field in terms of genetic techniques over the last 10 years, and even over the last 30 years. There's just been so many diseases that have been identified genetically. So, I think that's a really important take-home message. The other take-home message is that the first drug to treat Friedreich's ataxia, called omaveloxolone, came about about two years ago. This was also a really landmark discovery. As you know, a lot of these ataxias are very difficult to treat. Dr Grouse: Now pivoting back to thinking about the approach to diagnosis of ataxia, how does the timeline of the onset of ataxia symptoms inform your approach? Dr Zesiewicz: The timeline is important because ataxia can be acute, subacute or chronic in nature. And the timeline is important because, if it's acute, it may mean that the ataxia took place over seconds to hours. This may mean a toxic problem or a hypoxic problem. Whereas a chronic ataxia can occur over many years, and that can inform more of a neurodegenerative or more of a genetic etiology. So, taking a very detailed history on the patient is very important. Sometimes I ask them, what is the last time you remember that you walked normal? And that can be a wedding, that can be a graduation. Just some timeline, some point, that the patient actually walked correctly before they remember having to hold onto a railing or taking extra steps to make sure that they didn't fall down, that they didn't have imbalance. That sometimes that's a good way to ask the patient when is the last time they had a problem. And they can help you to try to figure out how long these symptoms have been going on. Dr Grouse: I really appreciate that advice. I will say that I agree, it can sometimes be really hard to get patients to really think back to when they really started to notice something was different. So, I like the idea of referencing back to a big event that may be more memorable to them. Now, given that framework of, you know, thinking through the timeline, could you walk us through your approach to the evaluation of a patient who presents to your clinic with that balance difficulties once you've established that? Dr Zesiewicz: Sure. So, the first thing is to determine whether the patient truly has ataxia. So, do they have imbalance? Do they have a wide base gait? That's very important because patients come in frequently to your clinic and they'll have balance problems, but they can have knee issues or hip issues, neuropathy, something like that. And sometimes what we say to the residents and the students is, usually ataxia or cerebellar symptoms go together with other problems, like ocular problems are really common in cerebellar syndromes. Or dysmetria, pass pointing, speech disorder like dysarthria. So, not only do you need to look at the gait, but you should look at the other symptoms surrounding the gait to see if you think that the patient actually has a cerebellar syndrome. Or do they have something like a vestibular ataxia which would have more vertigo? Or do they have a sensory ataxia, which would occur if a person closes his eyes or has more ataxia when he or she is in the dark? So, you have to think about what you're looking at is the cerebellar syndrome. And then once we look to see if the patient truly has a cerebellar syndrome, then we look at the age, we look at---as you said before, the timeline. Is this acute, subacute, or chronic? And usually I think of ataxia as falling into three categories. It's either acquired, it's either hereditary, or it's neurodegenerative. It can be hereditary. And if it's not hereditary, is it acquired, or is it something like a multiple system atrophy or a parkinsonism or something like that? So, we try to put that together and start to narrow down on the diagnosis, thinking about those parameters. Dr Grouse: That's really a helpful way to think through it. And it is true, it can get very complex when patients come in with balance difficulties. There's so many things you need to think about, but that is a great way to think about it. Of course, we know that most people who come in to the Movements Disorders clinic are getting MRI scans of their brains. But I'm curious, in which cases of patients with cerebellar ataxia do you find the MRI to be particularly helpful in the diagnosis? Dr Zesiewicz: So, an MRI can be very important. Not always, but- so, something like multiple system atrophy type C where you may see a hot cross bun sign or a pontine hyperintensity on the T2-weighted image, that would be helpful. But of course, that doesn't make the diagnosis. It's something that may help you with the diagnosis. In FXTAS, which is fragile X tremor/ataxia syndrome, the patient may have the middle cerebellar peduncle sign or the symmetric hyperintensity in the middle cerebellar peduncles, which is often visible but not always. Something like Wernicke's, where you see an abnormality of the mammillary bodies. Wilson's disease, which is quite rare, T2-weighted image may show hyperintensities in the putamen in something like Wilson's disease. Those are the main MRI abnormalities, I think, with ataxia. And then we look at the cerebellum itself. I mean, that seems self-evident, but if you look at a sagittal section of the MRI and you see just a really significant atrophy of the cerebellum, that's going to help you determine whether you really have a cerebellar syndrome. Dr Grouse: That's really encouraging to hear a good message for all of us who sometimes feel like maybe we're missing something. It's good to know that information can always come up down the line to make things more clear. Your article does a great review of spinal cerebellar ataxia, but I found it interesting learning about the more recently described syndrome of SCA 27B. Would you mind telling us more about that and other really common forms of SCA that's good to keep in mind? Dr Zesiewicz: Sure. So, there are now 49 types of spinal cerebellar ataxia that have been identified. The most common are the polyglutamine repeat diseases: so, spinocerebellar ataxia type 3 or type 2, type 6, are probably the most common. One of the most recent spinocerebellar ataxias to be genetically identified and clinically identified is spinocerebellar ataxia 27B. This is caused by a GAA expansion repeat in the first intron of the fibroblast growth factor on chromosome 13. And the symptoms do include ataxia, eye problems, downbeat nystagmus, other nystagmus, vertical, and diplopia. It appears to be a more common form of adult-onset ataxia, and probably more common than was originally thought. It may account for a substantial number of ataxias, like, a substantial percentage of ataxias that we didn't know about. So, this was really a amazing discovery on SCA 27B. Dr Grouse: Now a lot of us I think feel a little anxious when we think about genetic testing for ataxia simply because there's so many forms, things are changing quickly. Do you have a rule of thumb or a kind of a framework that we can think of as we approach how we should be thinking about getting genetic testing for the subset of patients? Dr Zesiewicz: Sure. And I think that this is where age comes into play a lot. So, if you have a child who's 10, 11, or 12 who's having balance problems in the schoolyard, does not have a history of ataxia in the family, the teachers are telling you that the child is not running correctly, they're having problems with physical education, that is someone who you would think about testing for Friedreich's ataxia. A preteen or a child, that would be one thing that would be important to test. When you talk to your patient, it's important to really take a detailed family history. Not just mom or dad, but ethnicity, grandparents, etc. And sometimes, once in a while, you come up with a known spinal cerebellar ataxia. Then you can just test for that. So, if a person is from Portugal or has Portugal background and they have ataxia and the parents had ataxia, you would think of spinal cerebellar ataxia type 3. Or if they're Brazilian, or if the person is from a certain area of Cuba and mom and dad had ataxia and that person has ataxia, you would think of spinal cerebellar ataxia type 2. Or if a person has ataxia and their parent had blindness or visual problems, you may be more likely to think of spinal cerebellar ataxia type 7, for example. If they have that---either they have a known genetic cause in in the family, first degree family, or they come from an area of the world in which we can pinpoint what type we think it is---you can go ahead and get those tests. If not, you can take an ataxia comprehensive panel. Many times now, if you take the panel and the panel is negative, it will reflex to the whole exome gene sequencing, where we're finding really unusual and more rare types of ataxia, which are very interesting. Spinal cerebellar ataxia type 32, spinal cerebellar ataxia type 36, I had a spinal cerebellar ataxia type 15. So, I think you should start with the age, then the family history, then where the person is from. And then, if none of those work out, you can get a comprehensive panel, and then go on to whole exome gene sequencing. Dr Grouse: That's really, really useful. Thank you so much for breaking that down in a really simple way that a lot of us can take with us. Pivoting a little bit now back towards different types of acquired ataxias, what are some typical lab tests that you recommend for that type of workup? Dr Zesiewicz: Again, if there's no genetic history and the person does not appear to have a neurodegenerative disease, we do test for acquired ataxias. Acquired ataxias can be complex. Many times, they are in the autoimmune family. So, what we start with are just basic labs like a CBC or a CMP, but then we tried to look at some of the other abnormalities that could cause ataxia. So, celiac disease, stiff person syndrome. So, you would look at anti-glutamic acid decarboxylase antibodies, Hashimoto's---so, antithyroglobulin antibodies or antithyroperoxidase antibodies would be helpful. You know, in a case of where the patients may have an underlying neoplasm, maybe even a paraneoplastic workup, such as an anti-Hu, anti-Yo, anti-Ri. A person has breast cancer, for example, you may want to take a paraneoplastic panel. I've been getting more of the anti-autoimmune encephalitis panels in some cases, that were- that are very interesting. And then, you know, things that sometimes we forget now like the syphilis test, thyroid-stimulating test, take a B12 and folate, for example. That would be important. Those are some of the labs. We just have on our electronic chart a group of acquired labs for ataxia. If we can't find any other reason, we just go ahead and try to get those. Dr Grouse: Now, I'm curious what you think is the most challenging aspect of diagnosing a patient with cerebellar ataxia? Dr Zesiewicz: So, for those of us who see many of these patients a day, some of the hardest patients are the ones that---regardless of the workup that we do, we've narrowed it down, it's not hereditary. You know, they've been through the whole exome gene sequencing and we've done the acquired ataxia workup. It doesn't appear to be that. And then we've looked for parkinsonism and neurodegenerative diseases, and it doesn't appear to be that either; like, the alpha-synuclein will be negative. Those are the toughest patients, where we think we've done everything and we still don't have the answer. So, I've had patients in whom I've taken care of family members years and years ago, they had a presumed diagnosis, and later on I've seen their children or other family members. And with the advent of the genetic tests that we have, like whole exome gene sequencing, we have now been able to give the patient and the family a definitive diagnosis that they didn't have 25 years ago. So, I would say don't give up hope. Retesting is important, and as science continues and we get more information and we make more landmark discoveries in genetics, you may be better able to diagnose the patient. Dr Grouse: I was wondering if you had any recommendations regarding either some tips and tricks, some pearls of wisdom you can impart to us regarding the work of ataxia, or conversely, any big pitfalls that you can help us avoid? I would love to hear about it. Dr Zesiewicz: Yeah, there's no easy way to treat or diagnose ataxia patients. I've always felt that the more patients you see- and sounds easy, but the more patients you see, the better you're going to become at it, and eventually things are going to fall into place. You'll begin to see similarities in patients, etc. I think it's important not only to make sure that a person has ataxia, but again, look at the other signs and symptoms that may point to ataxia that you'll see in a cerebellar syndrome. I think it's important to do a full neuroexam. If a person has spasticity, that may point you more towards a certain type of ataxia than if a person has no reflexes, for example, that we see in Friedreich's ataxia. Some of the ocular findings are very interesting as well. It's important to know if a person has a tremor. I've seen several Wilson's disease cases in my life with ataxia. They're very important. I think a full neuroexam and also a very detailed history would be very helpful. Dr Grouse: Tell us about some promising developments in the diagnosis and management of ataxia that we should be on the lookout for. Dr Zesiewicz: The first drug for Friedreich's ataxia was FDA-approved two years ago, which was an NRF2 activator, which was extremely exciting and promising. There are also several medications that are now in front of the FDA that may also be very promising and have gone through long clinical trials. There's a medication that's related to riluzole, which is a medication used for amyotrophic lateral sclerosis, that has been through about seven years of testing. That is before the FDA as well for spinal cerebellar ataxia. Friedreich's ataxia has now completed the first cardiac gene therapy program with AAV vectors, which- we're waiting for full results, but that's a cardiac test. But I would assume that in the future, neurological gene therapy is not far behind if we've already done cardiac gene therapy and Friedreich's ataxia. So, you know, some of these AAV vector-based genetic therapies may be very helpful, as well as ASO, antisense oligonucleotides, for example. And I think in the future, other things to think about are the CRISPR/Cas9 technology for potential treatment of ataxia. It is a very exciting time, and some major promising therapies have been realized in the past 2 to 3 years. Dr Grouse: Well, that's really exciting, and we'll all look forward to seeing these becoming more clinically applicable in the future. So, thank you so much for coming to talk with us today. Dr Zesiewicz: Thank you. Dr Grouse: Again, today I've been interviewing Dr Theresa Zesiewicz about her article on ataxia, which appears in the August 2025 Continuum issue on movement disorders. Be sure to check out Continuum Audio episodes from this and other issues, and thank you to our listeners for joining today. Dr Monteith: This is Dr Teshamae Monteith, Associate Editor of Continuum Audio. If you've enjoyed this episode, you'll love the journal, which is full of in-depth and clinically relevant information important for neurology practitioners. Use the link in the episode notes to learn more and subscribe. AAN members, you can get CME for listening to this interview by completing the evaluation at continpub.com/audioCME. Thank you for listening to Continuum Audio.

A collaborative study by the Clinic for Special Children in Lancaster and the Children’s Hospital of Philadelphia has identified an ultra-rare genetic disorder called complement factor I (CFI) deficiency, which is significantly more prevalent in individuals of Old Order Amish ancestry.Support WITF: https://www.witf.org/support/give-now/See omnystudio.com/listener for privacy information.

Michael Sobolik.Gordon Chang. China's Biowarfare Ambitions Threaten US Dominance and Global Health. China's Communist Party develops biowarfare, including ethnic-specific genetic attacks, to achieve strategic dominance over the US. China aims to divert US biotech innovation and control future vaccine distribution, leveraging lessons from COVID-19. US vaccine hesitancy and decreased investment in cutting-edge technology leave it dangerously exposed to future biothreats. 1906 PEKING DRUM TOWER

Genetic testing is more than just ancestry results. It can be one of the most powerful tools for supporting your child's long-term health and making informed medical decisions. In this empowering episode, Dr. Elana is joined by board-certified genetic counselor, Natalie Samson, to explore how DNA testing can help personalize everything from supplements to nutrition, vaccine protocols and emotional well-being. One of the most important parts of this conversation is how genetic insights can help assess vaccine risk. You'll learn how inflammation markers, methylation, detox pathways and oxidative stress genes can influence how a child responds to vaccines. With this information, parents can feel more confident in their ability to support their child's unique biology before and after vaccines. Natalie makes complex science feel easy to understand, offering real-life examples for moms who want clarity, not confusion. Dr. Elana also shares how genetic testing helped her tailor supplement plans, prepare for pregnancy and feel more grounded in her family's health decisions. Whether you are planning for pregnancy, navigating chronic symptoms, or facing vaccine decisions, this episode offers trusted education and encouragement so you feel informed and prepared. Topics Covered In This Episode: Genetic testing for personalized health plans How epigenetics influences chronic disease risk DNA-based vaccine risk assessment and immune support Understanding detox pathways and inflammation markers How genetic insights guide nutrition and supplement choices Supporting children's emotional health through neurotransmitter genetics Show Notes: Mention this podcast episode, and you can get 15% off an appointment with Natalie Follow @goldengeneticshealth on Instagram Click here to learn more about Dr. Elana Roumell's Doctor Mom Membership, a membership designed for moms who want to be their child's number one health advocate! Click here to learn more about Steph Greunke, RD's online nutrition program and community, Postpartum Reset, an intimate private community and online roadmap for any mama (or mama-to-be) who feels stuck, alone, and depleted and wants to learn how to thrive in motherhood. Listen to today's episode on our website Natalie is a dedicated Board-Certified Genetic Counselor devoted to transforming healthcare through personalized, integrative, and preventative approaches. She established her own practice, Golden Genetics to introduce an integrative and holistic approach to genetic counseling and testing, combining it with nutrition and nutrigenomics. She focuses on cancer, neurology and nutrigenomics and she aims to provide preventative and personalized care in genetic counseling and testing. This Episode's Sponsors  Enjoy the health benefits of PaleoValley's products such as their supplements, superfood bars and meat sticks.  Receive 15% off your purchase by heading to paleovalley.com/doctormom  Discover for yourself why Needed is trusted by women's health practitioners and mamas alike to support optimal pregnancy outcomes. Try their 4 Part Complete Nutrition plan which includes a Prenatal Multi, Omega-3, Collagen Protein, and Pre/Probiotic. To get started, head to thisisneeded.com, and use code DOCTORMOM20 for 20% off Needed's Complete Plan! Active Skin Repair is a must-have for everyone to keep themselves and their families healthy and clean.  Keep a bottle in the car to spray your face after removing your mask, a bottle in your medicine cabinet to replace your toxic first aid products, and one in your outdoor pack for whatever life throws at you.  Use code DOCTORMOM to receive 20% off your order + free shipping (with $35 minimum purchase). Visit BLDGActive.com to order. INTRODUCE YOURSELF to Steph and Dr. Elana on Instagram. They can't wait to meet you! @stephgreunke @drelanaroumell Please remember that the views and ideas presented on this podcast are for informational purposes only.  All information presented on this podcast is for informational purposes and not intended to serve as a substitute for the consultation, diagnosis, and/or medical treatment of a healthcare provider. Consult with your healthcare provider before starting any diet, supplement regimen, or to determine the appropriateness of the information shared on this podcast, or if you have any questions regarding your treatment plan.

For decades, we’ve been told that humans and chimpanzees are 99% genetically identical a claim repeated in museums, textbooks and by science celebrities like Bill Nye. But new genomic research tells a very different story. In this episode, Dr. Casey Luskin joins to reveal why the “1% difference” statistic is outdated, misleading, and scientifically inaccurate. We discuss how this number became one of evolution’s most popular talking points, why it persists despite being debunked, and what the latest studies actually show about human-chimp DNA. READ: Casey's Article: https://nypost.com/2025/07/26/opinion/smithsonian-exhibit-monkeys-around-with-the-scientific-evidence-on-human-origins/ *Get a MASTERS IN APOLOGETICS or SCIENCE AND RELIGION at BIOLA (https://bit.ly/3LdNqKf) *USE Discount Code [SMDCERTDISC] for 25% off the BIOLA APOLOGETICS CERTIFICATE program (https://bit.ly/3AzfPFM) *See our fully online UNDERGRAD DEGREE in Bible, Theology, and Apologetics: (https://bit.ly/448STKK) FOLLOW ME ON SOCIAL MEDIA: Twitter: https://x.com/Sean_McDowell TikTok: https://www.tiktok.com/@sean_mcdowell?lang=en Instagram: https://www.instagram.com/seanmcdowell/ Website: https://seanmcdowell.org Discover more Christian podcasts at lifeaudio.com and inquire about advertising opportunities at lifeaudio.com/contact-us.

“There is always a reason for illness. You may not have all your answers today, but that doesn't mean answers don't exist. Never give up.” – Dr. Diana DriscollIn this episode, Dr. Diana Driscoll — optometrist, researcher, patient, and founder of POTS Care — takes us inside her groundbreaking journey to uncover the hidden mechanisms of Postural Orthostatic Tachycardia Syndrome (POTS).After years of worsening illness and dismissal by the medical system, Dr. Driscoll combined her medical expertise with relentless patient-driven research. What emerged is now known as the Driscoll Theory, a framework that explores:What drives POTS: high intracranial pressure, vagus nerve dysfunction, neurotransmitter disruption, and systemic vascular irregularities.How to intervene: restoring vagus nerve function, reducing inflammation, supporting acetylcholine activity, and managing oxidative stress.Practical tools: supplements like ParaSym Plus and NAC Max, targeted use of histamine blockers, and non-invasive approaches to improving quality of life.Emotional resilience: how she navigated years of invalidation, supported her sick child, and created POTS Rebels, a community for patients seeking hope and science-backed solutions.This conversation is both deeply personal and highly practical, offering clarity for patients, practitioners, and caregivers searching for answers.00:00 – 02:00 | Intro & sponsor message (Healthgevity) Healthgevity our sponsor : ⁠Website⁠ Enter: ONETHING for a 10% discount02:00 – 03:00 | Adam introduces Dr. Driscoll & her personal journey with POTS03:00 – 08:00 | The turning point: realizing medicine had no answers → “I'm on my own”08:00 – 13:00 | Discovering high intracranial pressure and what eye patterns reveal14:00 – 18:00 | The emotional toll & why she built the POTS Rebels community19:00 – 24:00 | The what: inflammation as the hidden driver of POTS25:00 – 33:00 | The how: vagus nerve, acetylcholine, nicotine patch experiment, and ParaSym Plus34:00 – 38:00 | Genetic predisposition, hypermobility, and EDS connections38:00 – 41:00 | Identifying intracranial pressure symptoms (coat hanger pattern, nausea, insomnia)41:00 – 44:00 | Framework for healing: vagus support, histamine blockers, antioxidants45:00 – 48:00 | Take-home: “Never give up. Illness always has a reason.”49:00 | Closing thoughts & listener call-to-actionPOTS Care → potscare.comPOTS Rebels community → [Patreon link if available]TJ Nutrition (ParaSym Plus, NAC Max) → tjnutrition.comHealthgevity our sponsor : ⁠Website⁠ Enter: ONETHING for a 10% discount

Why do conditions like MCAS, hEDS, POTS, autoimmunity, and chronic stress so often appear together? And more importantly...can they be reversed? In this episode, I sit down with Adrian Davidson, a writer and researcher exploring the intersections of health, wellness, politics, and pop culture. Adrian has a lifelong passion for storytelling and brings a perspective that is both critical and compassionate. She dives into everything from health theories to cultural phenomena, blending broader commentary with her own lived experiences on her socials.Adrian has reversed multiple complex conditions in her own life, including: Mast Cell Activation Syndrome (MCAS)Multiple Autoimmune conditionsAnemiaInfertilityHypothyroidismNarcolepsyAnxiety, OCD, ADHD, hallucinationsAutism and Gender DysphoriaIBSShe opens up about what it was like to live with these challenges, how they interconnected, and the steps she took to truly heal. We dive into:What the RCCX cluster is and how it links MCAS, POTS, hEDS, and moreThe connection between genes, trauma, and nervous system stressHow Adrian turned her own health around—moving from illness and infertility to resilience, thriving, and having her 3rd baby at 40.What you can do if you suspect these patterns are at play in your life✨ This episode blends science, lived experience, and hope. If you've ever felt “wired differently” or stuck in cycles of reactivity and illness, Adrian's story will show you that reversal and healing are possible. You can find her curating visual storytelling on Instagram @capitalism.and.glitter and sharing longer-form writing on her Substack. Substack:https://adriandavidson.substack.com/welcomeInstagram: https://www.instagram.com/capitalism.and.glitter/Copywrite @AmandaPanacea Lets work together!· https://thehealerrevolution.com/ · Learn about my testing and coaching services: https://youtu.be/U7o17WErb84si=aaDZyp7txO6txtzm · Free 15 mins clarity call https://l.bttr.to/cih5BMy Most popular Courses, Guides, and Product Referrals· Product Links https://shopmy.us/amandapanacea· Feel to Heal: Transform Triggers into Calm (My signature course): https://feeltoheal.co/ · MCAS and histamine intolerance guide https://www.feeltoheal.co/webinar-registration· How to Heal MCAS and Histamine Intolerance Webinar: https://l.bttr.to/3Qnmv · HolyHydrogen Molecular Hydrogen: https://holyhydrogen.com/Panacea · King Coffee (Reishi spore infused organic coffee): https://thehealerrevolution.myorganogold.com/en/premium-gourmet-king-of-coffee/ Are you a practitioner, coach, or want to be? · Get certified in Bioenergetic testing: https://bioenergetics.learnworlds.com...· Learn HTMA and sign up for the HTMA app: https://hairanalysis.report/ref/165/ · Learn how to use and source Peptides (for non practitioners also!): https://amandapanacea--designergenes.thrivecart.com/pepsquad/ · Functional Genomics and Epigenetics: https://thedesignergenesco.com/bbd?affiliate=amandapanacea · Learn to read Mold labs and OAT: https://amandapanacea.krtra.com/t/4yQ7W1qjLT9cBuy my 365 day Somatic Manifestation Journal: https://www.amazon.com/dp/B0CQNSKXWD#AdrenalFatigue #anxietyrelief #bioenergetics #neuroscience #brainretraining #somatichealing #ChronicStress #hrv #functionalfreeze #AdrenalSupport #fightflightfreeze #nervoussytemregulation #nervoussystem #bloodsugar #anxiety #burnout #functionalmedicine #htma #bioenergetictesting #mcas #eczema #lyme #moldillness #gutbrainconnection #lymedisease #mastcellactivationsyndrome #tsw #topicalsteroidwithdrawal #guthealth #mineralbalancing #circadianrhythms #mastcellactivation #frequencyhealing #allergyrelief #weightloss #peptides #stressrelief #traumahealing #peptidesforweightloss #Bioenergetictesting

Host: Darryl S. Chutka, M.D. Guests: Thais D. Coutinho, M.D., and Kristen A. Sell-Dottin, M.D. Genetic factors predispose selected individuals to hereditary aortic aneurysms leading to aortic dilation and potential dissection.  They can be seen in a variety of known genetic syndromes, and they differ from aortic aneurysms associated with aging and chronic, uncontrolled hypertension. Early recognition is critical in the management of these patients in preventing serious, often life-threatening aortic dissection. How common are hereditary aortic aneurysms? When and how should we screen patients for this condition? Is a genetic consultation recommended? When should we involve a vascular surgeon when at risk patients are identified? These are some of the questions I'll be asking my guests, Thais D. Coutinho, M.D., a cardiologist and cardiac surgeon, Kristen A. Sell-Dottin, M.D., both from the Mayo Clinic. We'll be discussing “Hereditary Aortic Aneurysms and Dissection” as part of our podcast series on “Peripheral Vascular Disease”. Mayo Clinic Talks: Vascular Medicine Series | Mayo Clinic School of Continuous Professional Development Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts 

Dr. Dillon Pruett has lived both sides of stuttering: the anxious kid rehearsing every word and the scientist searching DNA for answers. His groundbreaking research, recently published in Nature Genetics, uncovered 57 genetic hotspots tied to stuttering -- proof that our voices carry a biological story as complex as any human trait. In our conversation, Dillon shares how his personal journey shaped his path into research, what the findings reveal about stuttering's overlap with traits like musicality and sleep, and why the goal isn't to “fix” stuttering but to demystify it. At its heart, this episode is about turning stigma into science and science back into compassion.You can read the study here. -----

In this episode of The Lindsay Elmore Show, Lindsay sits down with David Roberts, co-founder of Mara Labs and a pioneer in sulforaphane supplementation.Sulforaphane, derived from broccoli sprouts, has been called the "master molecule for health" thanks to its ability to support detoxification, reduce inflammation, enhance brain health, and improve metabolic function. David shares the science behind stabilizing sulforaphane, explains why most supplements fall short, and discusses its synergistic effects with molecules like curcumin. From detoxing microplastics to balancing hormones and boosting mitochondrial energy, sulforaphane has far-reaching benefits for overall resilience.Key TakeawaysSulforaphane Basics: A compound found in broccoli sprouts with over 37 documented pro-health mechanisms.Brain Health: Increases BDNF, supporting neuroprotection, neurogenesis, and even enhanced dreaming.Detoxification: Activates NRF2 pathways, turning on over 200 antioxidant and detox genes for up to 72 hours.Inflammation: Synergizes with curcumin to reduce NF-kB and IL-6, two key pro-inflammatory markers.Practical Use: Each capsule of Mara Labs' stabilized sulforaphane equals the benefit of 2.5 pounds of broccoli.Metabolic Impact: Helps balance estrogen, supports mitochondrial energy, and assists in reducing belly fat and insulin resistance.Environmental Defense: Aids the body in processing toxins like glyphosate and mobilizing microplastics.Chapter Timestamps01:00 – What is sulforaphane and why it's the “master molecule”03:00 – How sulforaphane supports brain health through BDNF05:00 – Stabilizing sulforaphane and the challenges of supplementation06:45 – David's personal story: breast cancer diagnosis and discovery of sulforaphane08:00 – How sulforaphane is delivered and stabilized in capsules10:00 – The NRF2 pathway and turning on antioxidant defense13:00 – Detox done right: why many “detox programs” fail15:00 – Curcumin and sulforaphane synergy for inflammation reduction18:00 – Internal studies on inflammation markers (IL-6, NF-kB)20:00 – The real role of detoxification vs. buzzwords24:00 – Toxins in modern life: microplastics, glyphosate, and more28:00 – Genetic modification, glyphosate, and long-term toxicity29:30 – Sulforaphane for metabolism, mitochondrial energy, and belly fat32:00 – Additional Mara Labs products supporting metabolism (GLP-1 alternatives)33:00 – How to learn more: Mara Labs discount link

My guest is Dr. Sergiu Pașca, MD, professor of psychiatry and behavioral sciences at Stanford University. We discuss the biology and genetics of autism, why autism diagnoses are increasing and recent progress in using stem cells to understand and treat profound autism and other brain disorders. Dr. Pașca explains “organoids and assembloids”—human stem cell–derived tools he pioneered to study, treat and cure complex brain diseases. We also discuss ethical and safety issues with using gene editing and stem cells in humans. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman David: https://davidprotein.com/huberman Helix: https://helixsleep.com/huberman BetterHelp: https://betterhelp.com/huberman Function: https://functionhealth.com/huberman Timestamps (00:00) Sergiu Pașca (02:08) Autism Spectrum Disorder, Incidence, Genetics (07:16) Is Autism More Common in Males? (09:35) Sponsors: David & Helix Sleep (11:56) Eye Contact in Babies, Fever; Proposed Causes of Autism; Genes (18:48) Genetic or Idiopathic Autism Diagnoses, Timothy Syndrome (21:37) Rise in Autism Diagnoses (26:46) Cause, Correlation & Neurological Disease; Schizophrenia, Do Vaccines Cause Autism? (31:34) Global Increase in Autism; Gene Therapy, CRISPR, Follistatin (41:05) Sponsors: AG1 & BetterHelp (43:41) Stem Cells, Ethics, Yamanaka Factors, Human Stem Cell Models (52:03) Umbilical Stem Cells; Stem Cell Injections & Dangers, Autistic Kids (59:30) Organoids, Modeling Brain Development, Intrinsic Development Timer (1:12:22) Assembloids, Brain Cell Migration & Circuit Formation, Self-Organization (1:21:22) Four-Part Assembloid, Sensory Assembloid, Pain Conditions (1:25:45) Sponsor: Function (1:27:33) Future Medical Therapies, Cell Banking, Immortalize Tissues, Rejuvenate Cells (1:34:56) Assembloids & Ethics, Importance of Nomenclature, Science Collaboration & Self-Correction (1:45:38) Cell Transplantation & Ethics, Timing (1:55:05) Genetic Testing for Parents, Genetic Penetrance (2:02:36) Assembloids, Timothy Syndrome, Epilepsy, Schizophrenia, Dystonia (2:14:30) Scientific Career, Walking, Art, Medical School (2:20:44) Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices