Podcasts about Genetic

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Brian Grosberg is a world-renowned headache specialist who joins Peter to provide a master class on the diagnosis and treatment of headache disorders. In this episode, Brian explains the distinction between primary and secondary headaches and breaks down the defining features of the "big three" primary headache types (migraine, cluster, and tension headache)—highlighting how often they are misdiagnosed and how they are treated. He explores the epidemiology of headaches, describing migraine as an invisible disease affecting about 12% of the population, disproportionately affecting women, while cluster headaches more often affect men. He discusses the major gap between demand for headache care and available specialists, and he offers advice on when to see a physician. Brian dives into the multifactorial nature and pathophysiology of migraine, including genetic and hormonal influences, neurovascular changes, and inflammatory signaling, and connects these mechanisms to modern therapies. Throughout the conversation, he emphasizes the individualized nature of headache disorders and the importance of a detailed headache diary. Brian shares practical strategies for treating headaches including lifestyle changes, medications, and neuromodulation devices. We discuss: Brian's interest in headaches and how Peter met Brian [2:15]; Differentiating the types of headaches: primary versus secondary headache and tension versus migraine headache [7:30]; The epidemiology and burden of migraine, its disproportionate affect on women, and the shortage of headache specialists [20:00]; Genetic susceptibility to migraine and the role of hormones [24:45]; Migraine triggers, the impact of hormones, and the importance of a headache diary [31:15]; The phases of a migraine: premonitory symptoms, aura, the headache itself, and the postdrome [38:15]; Tension headaches: symptoms, causes, and prevalence [41:45]; Cluster headaches: extreme pain, distinctive symptoms, and frequent misdiagnosis as a sinus infection or allergies [43:15]; Lifestyle interventions to prevent headaches [51:15]; Pharmacological treatments to prevent headaches [1:05:00]; What's known about the pathophysiology of migraines: neurovascular changes, release of neuropeptides, and inflammatory response [1:14:45]; CGRP antagonists for the treatment of migraines: large monoclonal antibodies and gepants [1:20:15]; Use of calcium channel blockers and Botox to treat cluster headache and migraine [1:28:30]; Drugs for the acute treatment of migraines [1:32:30]; Treatment of migraines with electrical stimulation devices [1:40:00]; Use of THC or cannabis to treat headaches [1:44:00]; What Brian wants people to know about headaches [1:45:45]; Brian's advice on when to see a doctor about headaches and how to prepare for that visit [1:49:15]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

Have you ever noticed how two women fifteen years apart can seem worlds apart in energy, while two women the same age can be aging in completely different directions? In this episode of The Art of Living Well Podcast®, Marnie and Stephanie unpack what they call the midlife health dashboard: the metrics that actually predict how well you're aging, beyond the number on a biological age test. They share their own results from two different biological age tests, including a jarring 16-year gap between the two, and walk through what's actually within your control. Biological age testing has exploded in popularity, with people online sharing scores and spending real money to find out if they're aging faster or slower than their birth certificate says. Marnie and Stephanie have both taken these tests themselves, and they break down what the scores actually mean, what they missed, and why the number matters far less than the daily habits behind it. Whether you've taken a biological age test, are curious about one, or just want a practical way to think about aging well, this episode gives you a place to start today. Key Takeaways: •Biological age tests compare you to other people who took that same test, often a health-conscious group, not the general population •Genetic testing can also reveal your MTHFR status and ApoE genotype, which may be more useful day to day than the biological age score itself •Getting up off the floor without using your hands is one of the simplest predictors of long-term mobility •Walking pace and small daily movement snacks measurably affect how well you age, not just how far you walk •Deep sleep, not just total hours, is one of the most overlooked levers for energy and recovery in midlife •Most women are still under-eating protein, and it shows up in blood work, energy, and cravings •Chronic stress and time spent in fight-or-flight directly affects your biological age, not just how you feel day to day •You don't need a lab test to start improving your health dashboard, an honest self-score across a few key areas is a good place to begin Episode Breakdown with Timestamps: 00:00 Why Two Women 15 Years Apart Can Age So Differently 00:59 Welcome Back: Introducing the Midlife Health Dashboard 01:28 What Biological Age Actually Measures 01:55 Stephanie's Biological Age Test Results, Explained 04:34 Marnie's Two Test Results: One Said 54, One Said 38.6 07:37 The MTHFR Gene and Why Methylation Matters 08:49 Genes Aren't Destiny: A Quick Note on Epigenetics 09:30 Metric: Muscle and Functional Strength 10:21 The "Can You Get Off the Floor" Longevity Test 10:49 Book Rec: The New Fit With Aaron Leventhal (Episode 284) 11:32 Metric: Walking, Movement Snacks, and Pace 13:49 Metric: Sleep and the Midlife Wake-Up Spiral 15:26 Sleep Trackers Worth Trying: Aura Ring vs. Whoop 16:30 Chasing Deep Sleep: What Actually Moved the Needle 17:44 Metric: Stress, the Nervous System, and a PEMF Mat Experiment 19:52 Metric: Protein, and Why Most Women Are Under-Eating It 22:15 Does Everyone Need to Take a Biological Age Test? 23:02 Metric: Connection and Purpose 23:59 Metric: Getting Out of Fight-or-Flight 24:59 Build Your Own Health Dashboard: Score Yourself 25:08 How Old Do You Actually Feel? 28:16 What We'd Tell Our Kids Now 29:21 Share Your Biological Age Results With Us 29:45 Join the Fall Vitality Reboot, Starting September 27 Resources and Links: Episode 267, The New Fit with Aaron Leventhal Episode284 with Danny King (Lifetime) on VO2 max  Episode 319 on Community and Longevity for Midlife Women  Episode317 Design a life you love with the "big ass calendar" co-founder  Feeling tired, inflamed, or stuck in a cycle of cravings? Join our 7-Day Fall Vitality Reboot starting September 27 and discover how much better you can feel with simple daily habits and a supportive community beside you every step of the way. Click here to save your spot: https://l.bttr.to/fNSbn Subscribe to our Substack to get episode updates, wellness tips, and personal reflections from Marnie & Stephanie delivered straight to your inbox. Grab your free Midlife Travel Resilience Checklist here. If you love the show and want to support what we're building, consider a paid subscription for $30 annually. https://theartoflivingwell.substack.com/ Follow & Connect: Instagram: https://www.instagram.com/theartofliving_well/ YouTube: https://www.youtube.com/@theartoflivingwellpodcast LinkedIn: https://www.linkedin.com/company/the-art-of-living-well-podcast/ TikTok: https://www.tiktok.com/@theartoflivingwel/ Spotify: https://open.spotify.com/show/4gym3jOPdSHwrpM1BmxyJz Apple Podcasts: https://podcasts.apple.com/us/podcast/the-art-of-living-well-podcast/id1482050468 Connect with Your Hosts: Marnie Dachis Marmet: https://www.instagram.com/zenfullifecoaching  Stephanie May Potter: https://www.instagram.com/stephaniemaypotter/  

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View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter In this "Ask Me Anything" (AMA) episode, Peter takes a deep dive into the liver and its central role in metabolic health. He explains why the liver can serve as a "canary in the coal mine" for metabolic dysfunction and explores how insulin resistance, visceral fat, alcohol consumption, genetics, and hormones contribute to liver disease, along with how increasing muscle mass can benefit liver health. Peter provides a framework for understanding the progression of liver disease, highlighting which stages are reversible and why early detection matters. He explains why normal liver enzymes can provide false reassurance, which labs he uses to assess liver health, and the tools available for detecting fibrosis and more advanced disease. Peter then breaks down the interventions that can meaningfully improve liver health once risk or disease is identified, ranging from diet and exercise to GLP-1–based therapies and other medications. Finally, he examines popular claims around liver "detoxification" and supplements, separating what is supported by evidence from what is unlikely to meaningfully improve liver health. If you're not a subscriber and are listening on a podcast player, you'll only be able to hear a preview of the AMA. If you're a subscriber, you can now listen to this full episode on your private RSS feed or our website at the AMA #88 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here. We discuss: Why the liver is the "canary in the coal mine" for metabolic dysfunction, and an overview of what the liver does [2:00]; The relationship between the liver and blood sugar control [6:30]; A framework for understanding how metabolic disease affects the liver [9:15]; Chronic caloric surplus and insulin resistance as drivers of liver disease [11:00]; Liver diseases that result from metabolic dysfunction and the difference between steatosis and fibrosis [15:15]; How visceral fat affects liver health [20:00]; The importance of lifestyle interventions for liver and metabolic health: resistance training, not drinking calories, and the impact of fructose [22:00]; Why alcohol-associated liver disease is more common than we give it credit for [26:30]; Genetic and hormonal risks for liver disease [31:45]; Labs that objectively measure liver health and the FIB-4 score [35:30]; FibroScan: non-invasive imaging of the liver [44:30]; The resiliency of the liver: an organ that can heal itself [47:00]; Fibrosis staging and its impact on mortality and cancer risk [49:15]; Interventions for someone with MASLD: weight loss and GLP-1s [52:00]; Other medications used to treat metabolic liver disease [57:00]; The role of exercise in treating metabolic liver disease: caloric deficit and building muscle [59:45]; The myth of liver detoxes and cleanses, and a few supplements that may benefit the liver [1:01:15]; A practical summary: how to assess your risk and the levers that reverse the disease [1:08:00]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

NEW EPISODE of the "Heart of Rural America" featuring Amanda Radke & Chris Earl, recorded on Aug. 15 at Reverse Rocking R Ranch, Maxwell, NM. Topics of discussion:In part one, Chris and Amanda talk about three exciting sales offering elite Angus genetics including:- Aug. 29: Musgrave Angus- Sept. 5: Rhoades Ranch - Sept. 12: CK6 Genetic Allies at Edgar BrothersIn part two, they unpack some of the biggest challenges in the beef cattle business today: - Market consolidation, facilities closing & the 85% monopoly holding the industry captive - Amanda's recent trips to Washington, D.C. to visit with the Trump administration and USDA Secretary Brooke Rollins- Truth in labeling, MCOOL, Substantial TransformationPart three ends on a positive note, as they offer some words of encouragement for the American cattle rancher on:- Leverage- Entrepreneurship- Marketing - Paving the way - Building relationships with your customers- Standing for the truth & living by your faithPresented by Bid On Beef | CK6 Consulting Services Inc. | CK6 Source | Real Tuff Livestock Equipment | Ambrook | Redmond Real Salt | All American Angus Beef | Radke Land & Cattle Listen to Steve Stratford's CATTLE CHAT here: https://www.facebook.com/p/Cattle-CHAT-100068146624164/ Use code RADKE for $10 off your next All American Angus Beef order at www.BidOnBeef.comSave on Redmond Real Salt with code RADKE at https://shop.redmondagriculture.com/Try a one-month trial with Ambrook for free here: ambrook.com/radke Check out Amanda's agricultural children's books here: https://amandaradke.com/collections/amandas-booksLearn more about Bulletproofing Your Direct-To-Consumer Beef Enterprise: https://amandaradke.com/products/bulletproof-your-beef-businessReport an issue with the USDA Lawfare portal: https://www.usda.gov/lawfare Join the property rights fight at American Land & Legacy. at www.americanlandandlegacy.org

Our dear friends invited us to an event this weekend in LA… they are partnering with Gary Brecka to build Ultimate Longevity Centers which will bring treatments and testing that just hasn't been easily accessible before now. I believe the way we look at aging is outdated and I'm going to share the biggest take aways I got from his on stage message and chatting with him one on one. We are talking about very practical starting points and Gary Brecka's actual morning health routine. Stop waiting until something is wrong to start taking care of your body. We have been taught this idea that getting older automatically means getting weaker, having less energy, gaining weight, losing muscle, sleeping worse, becoming more anxious, needing more medications and eventually developing all of the diseases that "run in our family." Gary challenges a lot of that thinking. His message is essentially… What if we became obsessed with keeping our bodies functioning incredibly well for as long as possible? What if instead of asking, "How do I treat disease once I have it?" we asked, "How do I create a body that is incredibly difficult for disease to thrive in?" And then there's the longevity piece that completely fascinates me. Gary believes we're entering a period where medicine, AI, biological data and longevity research are going to advance so rapidly that lifespan could look radically different in the future. Maybe 120. Maybe beyond. We don't know. But what we do know is that we need to keep ourselves healthy enough NOW to benefit from whatever becomes possible later. So today's episode is about doing the things that give you the strongest, healthiest, most capable body possible. I've been listening to Gary Brecka talk about health, longevity, anxiety, genetics, sleep, sunlight, oxygen, muscle, bloodwork and what he believes is coming next in longevity science. THE BIG IDEA: YOUR HEALTH IS BUILT EVERY DAY One of my biggest takeaways from Gary is that health isn't something we deal with when there's a problem. It's something we're building every single day. Your sleep last night matters. What you do when you wake up matters. Whether you move your body matters. Whether you maintain muscle matters. Your metabolic health matters. Your stress matters. Your relationships matter. Your nutrition matters. Your environment matters. And individually, none of these things feels life-changing. But repeated for years and decades… they become your life. Gary describes his routine as simple, portable and repeatable. I LOVE that. Because the best health routine isn't the $100,000 biohacking setup. It's the one you'll actually do every day. HABIT #1: HYDRATE BEFORE YOU DO ANYTHING ELSE Gary starts his morning with water and minerals. One version of his routine is a large glass of room-temperature water with mineral salt and sometimes lemon. His current routine also frequently includes mineral salt, hydrogen water and essential amino acids. Wake up and hydrate. You've just spent roughly eight hours without drinking anything. Don't make coffee your first liquid of the day. Put water next to your bathroom sink. Put it next to your coffee machine. Make it automatic. Gary likes mineral salt because sodium and other minerals participate in fluid balance and normal nerve and muscle function. HABIT #2: GET OUTSIDE FIRST THING Gary says to get outside within the first part of your morning and get natural outdoor light into your eyes. His routine generally calls for about 10 minutes outside. Morning light helps tell your brain: It's daytime. Start the clock. Light is one of the strongest environmental signals for the circadian system. Properly timed morning light can shift circadian timing earlier and increase daytime alertness. And I love thinking of sleep this way: Your good night's sleep starts in the morning. We tend to think sleep health starts when we crawl into bed. But your body has been receiving signals all day telling it when to be awake and when to prepare for sleep. HABIT #3: BREATHE ON PURPOSE Gary talks about oxygen constantly. His personal morning practice has included three rounds of deep breathing followed by breath holds. And this connects to another thing we've been talking about: Anxiety. I love the idea that when you feel anxious, you shouldn't immediately decide: "I'm an anxious person." Anxiety is a state your nervous system is experiencing. Sometimes your thoughts are driving your physiology. And sometimes your physiology can amplify anxious thoughts. Either way, changing the physical state can sometimes help change the mental state. Research on structured breathwork has found modest improvements in stress and anxiety, although it isn't a cure-all and the quality of studies varies. HABIT #4: GIVE YOUR BRAIN SILENCE Gary often combines his morning breathing with quiet, gratitude and reflection. He has described sitting quietly for around 10 minutes, looking toward the horizon or closing his eyes and thinking about gratitude. (PodScripts (https://podscripts.co/podcasts/the-ultimate-human-with-gary-brecka/246-gary-brecka-answers-googles-most-searched-questions-on-his-diet-wellness-and-lifestyle?utm_source=chatgpt.com)) Think about how different this is from what most of us do. Eyes open. Phone. Email. Instagram. News. Text messages. Stress. Other people's priorities. And we wonder why we feel overstimulated. TRY THIS: Before consuming everybody else's thoughts… Have some of your own. What am I grateful for? What matters today? Who needs me today? How do I want to feel today? What is actually important? PRACTICAL VERSION: Five minutes. That's it. No phone. No podcast. No input. Just quiet. HABIT #5: USE CONTROLLED DISCOMFORT Cold exposure is another major Brecka habit. If he has access to a cold plunge, he uses it. When traveling, he has said a cold shower works too. But I think there is a bigger lesson here than whether everybody needs to buy a cold plunge. Stop designing your entire life around comfort. Human beings are unbelievably adaptable. Exercise is stress. Heat is stress. Cold is stress. Fasting is stress. Challenging your brain is stress. The key is appropriate amounts of stress followed by recovery. HABIT #6: MOVE EARLY Gary includes movement in his morning routine. But here's what I love: It doesn't need to be a full workout. Walk. Stretch. Squat. Lift. Do yoga. Go outside. Movement tells your body: We're alive. We're using this machine today. And then keep moving after the morning is over. One exceptionally practical habit is walking after meals. Instead of finishing dinner and immediately sitting on the couch… WALK FOR 10 MINUTES. Moving skeletal muscle after eating can help the body handle glucose. You don't need workout clothes. You don't need a gym. You don't even need to sweat. Walk around your neighborhood. Walk your dog. Walk while you're on a phone call. ONE OF THE EASIEST HEALTH RULES: Eat → walk. HABIT #7: BUILD MUSCLE LIKE YOUR FUTURE DEPENDS ON IT This is where I think longevity conversations get really practical. MUSCLE IS NOT JUST ABOUT LOOKING GOOD. Maintaining muscle becomes increasingly important as we age. Resistance training is one of the most powerful non-drug strategies available for preserving and building skeletal muscle. Losing muscle eventually affects: strength balance mobility independence your ability to recover from illness your ability to do normal life You're not building your 2026 body. You're building your 2056 body. HABIT #8: PRIORITIZE PROTEIN AND REAL FOOD- avoid processed foods Gary emphasizes protein and essential amino acids because preserving lean tissue is a major part of his longevity philosophy. The research strongly supports resistance training for preserving muscle, while evidence regarding how much additional benefit comes from protein supplementation specifically is more mixed. HABIT #9: PROTECT YOUR METABOLIC HEALTH I think this deserves WAY more attention. We obsess over weight. Gary talks much more about metabolic health. There is a difference. Weight is one number. Metabolic health includes things like: blood glucose insulin sensitivity blood pressure blood lipids waist circumference fitness body composition Instead of only asking: "How much do I weigh?" Ask: "How well is my body functioning?" Someone can lose weight while losing muscle. Someone can be thin and still have poor metabolic health. PRACTICAL HABITS: Strength train. Walk. Walk after meals. Eat mostly whole foods. Get enough sleep. Maintain healthy body composition. Reduce constant snacking if it isn't serving you. Know your basic health numbers. THE GOAL ISN'T SKINNY. The goal is metabolically capable. HABIT #10: TEST… DON'T JUST GUESS This might be one of my favorite parts of Brecka's philosophy. Stop guessing about everything. If you're exhausted all the time… investigate. If you're unusually anxious… investigate. If your sleep has suddenly changed… investigate. If your energy has disappeared… investigate. If your hormones feel completely different… investigate. If you feel awful despite doing "everything right"… investigate. Don't immediately decide: "I'm getting old." "This runs in my family." "I'm just an anxious person." "My metabolism sucks." "This is just how I am." ASK BETTER QUESTIONS. Could something modifiable be contributing? sleep nutrient deficiencies thyroid function iron status medications hormones metabolic health stress alcohol caffeine environment psychological health This does NOT mean ordering every exotic test on the internet. It means becoming curious about your own biology. HABIT #11: DON'T TURN ANXIETY INTO YOUR IDENTITY This is worth repeating because I think this is such an important mental shift. Instead of: "I AM anxious." Try: "I'm experiencing anxiety." Those are very different statements. One is an identity. One is a temporary condition worth investigating. Gary's message leans heavily toward investigating biology. He talks about things like methylation pathways and MTHFR. There are legitimate genetic influences on anxiety. But anxiety is complex. Research suggests anxiety disorders arise through a combination of genetic vulnerability and environmental influences, not one single "anxiety gene." (PubMed (https://pubmed.ncbi.nlm.nih.gov/15699295/?utm_source=chatgpt.com)) So I would approach it from ALL DIRECTIONS: Calm the body. Investigate the biology. Work on the thoughts. Breathwork. Sleep. Exercise. Less overstimulation. Healthy relationships. Therapy when needed. Medical evaluation when something feels physiologically off. Nutrition. Less caffeine when appropriate. Time outdoors. Don't choose between: "It's psychological." or "It's biological." It can be both. HABIT #12: GENETICS ARE INFORMATION… NOT ALWAYS DESTINY This is another Gary Brecka concept that I think is incredibly empowering when we phrase it accurately. People say: "Diabetes runs in my family." "Anxiety runs in my family." "Heart disease runs in my family." "Autoimmune disease runs in my family." And we can start thinking: Well… I guess that's coming for me too. But genetics often represent susceptibility rather than certainty. Your genes can increase risk. Your environment can increase or decrease risk. Your behaviors matter. Your metabolic health matters. Your exposures matter. Your entire biological environment matters. So instead of thinking: "My family gets this disease." Think: "I may have inherited a vulnerability. What parts of that vulnerability can I modify?" THAT is empowering. Important distinction: Some diseases absolutely are caused by inherited genetic mutations. So we should not say: "Genetic diseases aren't real." They absolutely are. The better message is: Genes can load the gun. They don't always pull the trigger. And with many complex chronic diseases, what ultimately happens involves an interaction between genetics and environment. HABIT #13: STOP THINKING OF SLEEP AS LOST PRODUCTIVITY Sleep is when your body gets to repair. And Brecka's evening routine reflects this. He emphasizes regular sleep, reducing stimulation late at night and setting up the next morning by protecting the night before. My favorite way to think about sleep: Tomorrow starts tonight. Stop trying to squeeze another hour out of your day if it destroys tomorrow. Decide when you're going to bed BEFORE you're tired. Dim things down. Get off your phone. Stop working. Let the nervous system receive a signal that the day is ending. Pick a bedtime and protect it the same way you'd protect an important meeting. NOW LET'S TALK ABOUT LIVING TO 120 The speed of advancement is changing. AI can analyze enormous amounts of biological data. Diagnostics are improving. Scientists are studying the actual biology of aging rather than treating aging purely as an unavoidable decline. Researchers are investigating cellular senescence, epigenetics, regenerative medicine and other mechanisms associated with biological aging. Gary believes these developments could eventually change human lifespan dramatically. And his argument is essentially: Stay alive and stay healthy long enough to benefit from what's coming. That hit me HARD. Because imagine being 75 in the future… But instead of arriving at 75: metabolically sick weak frail sedentary cognitively struggling carrying multiple preventable chronic illnesses You arrive: strong metabolically healthy active engaged cognitively sharp sleeping well maintaining muscle surrounded by people you love THAT is the bridge. Not: "How do I live forever today?" But: "How healthy can I be when tomorrow's medicine arrives?" DON'T JUST CHASE LIFESPAN. CHASE HEALTHSPAN. I don't want to simply exist until I'm 120. I want to LIVE. I want to: travel walk everywhere lift my suitcase play with grandchildren hike swim think clearly learn new things have great conversations have energy be independent laugh have purpose wake up excited THAT is longevity. Not adding years at the end where you can't live. Adding life to the years. WHAT SHOULD WE ACTUALLY DO RIGHT NOW? If you took this entire episode and boiled it down into a daily longevity checklist… MORNING Hydrate. Get outside. Get natural morning light. Breathe intentionally. Spend a few minutes in quiet. Think about gratitude. Move your body. Use cold exposure if you enjoy it and it's appropriate for you. Don't immediately flood your brain with stress. DURING THE DAY Eat nutrient-dense real food. Prioritize protein. Strength train consistently. Walk. Walk after meals. Stay metabolically healthy. Maintain muscle. Build meaningful relationships. Have purpose. Keep learning. Get outside. NIGHT Stop eating mindlessly late into the evening. Reduce stimulation. Get off the phone. Give yourself a predictable bedtime. Sleep. THROUGHOUT YOUR LIFE Know your numbers. Do appropriate preventive screening. Investigate symptoms rather than ignoring them. Don't automatically assume something is "just aging." Don't automatically assume family history means destiny. Continue learning as science changes. Protect your muscle. Protect your metabolism. Protect your brain. Protect your relationships. Protect your sleep. THE SIMPLEST VERSION OF EVERYTHING GARY BRECKA IS SAYING 1. Get sunlight. 2. Breathe. 3. Hydrate. 4. Move. 5. Build muscle. 6. Eat real nutrient-dense food. 7. Protect your metabolism. 8. Sleep like it matters. 9. Challenge your body sometimes. 10. Investigate problems instead of simply accepting them. 11. Don't confuse genetic risk with guaranteed destiny. 12. Don't turn anxiety into your identity. 13. Build relationships and a life that gives you purpose. 14. Stay unbelievably healthy while longevity science continues advancing. And maybe most importantly… DON'T WAIT UNTIL YOU'RE SICK TO BECOME INTERESTED IN YOUR HEALTH. I learned that every single thing that gives me the best chance of being healthy at 120 also gives me a better life at 45. Getting sunlight tomorrow morning makes tomorrow better. Sleeping tonight makes tomorrow better. Building muscle makes this decade better. Eating well makes today better. Getting outside makes today better. Putting my phone down makes today better. Managing anxiety makes today better. Having people I love around me makes today better. So this isn't really an episode about trying to cheat death. It's about refusing to sleepwalk through your health. Your body is the vehicle that carries you through every single experience you're hoping to have. Every trip. Every adventure. Every business idea. Every dinner. Every workout. Every moment with your kids. Every future grandkid. Everything. So take ridiculously good care of it. And instead of looking at aging and thinking… "Well, I guess everything starts going downhill from here…" What if we thought completely differently? What if our goal was: I want to be stronger next year. Healthier next year. More metabolically healthy next year. More informed next year. More capable next year. And then do it again. And again. And again. For decades. Let's make the goal to be fully alive for as much of it as humanly possible. That's the health lesson I'm taking from Gary Brecka. Don't wait for the future of longevity medicine. Build the kind of body today that's ready for it.

Dr. Stora teaches us about the principles of maintaining healthy, sustainable breeding lines over multiple generations. Genetic hygiene, including inherited disease risk, genetic diversity, coefficient of inbreeding, selection pressure and long-term breed preservation, will help you make ethical, evidence-based decisions that protect the future of your lines.Watch the video version of the presentation here.

This program examines Rasnick's research, interpretations and personal views. It is presented for education and discussion only and is not medical advice. Viewers should consult qualified healthcare professionals before making medical decisions. This is a scientific discussion—not medical adviceToday on the Typical Skeptic Podcast, Robert Kalil welcomes biochemist and author Dr. David William Rasnick for a provocative discussion surrounding his new book, The Outsider: A Personal Odyssey into the Essence of Cancer.Drawing upon decades of research and more than a century of scientific debate, Dr. Rasnick challenges the dominant gene-mutation explanation of cancer. He argues that cancer may be better understood as a disease driven by chromosomal imbalance—known as aneuploidy—and chromosomal instability.Why do cancers progress, spread, recur and develop resistance? What did pioneering biologist Theodor Boveri recognize about abnormal chromosomes more than a century ago? Why did genetic mutation theories come to dominate cancer research, and what happens to scientists who question an established medical consensus?Part scientific investigation and part personal memoir, The Outsider recounts Rasnick's transformation from a conventional pharmaceutical and biotechnology researcher into an outspoken scientific dissident. We discuss institutional dogma, research funding, professional pressure, independent thought and the human cost of challenging powerful systems.David Rasnick earned his PhD in chemistry from Georgia Tech in 1978, spent approximately two decades working in the pharmaceutical and biotechnology industries, and previously authored The Chromosomal Imbalance Theory of Cancer. His new book was released in 2026 by TrineDay. Book informationThis program examines Rasnick's research, interpretations and personal views. It is presented for education and discussion only and is not medical advice. Viewers should consult qualified healthcare professionals before making medical decisions.Live Friday, August 14 at 10 AM EasternTypical Skeptic Podcast #2775We go deep. You decide.We go deep. You decide.“We Go Deep. You Decide.”Established 2019Ways to support the Typical Skeptic Podcast:PayPal: https://paypal.me/typicalskepticmediaCash App: $kalil1121Venmo: @robert-kalilBuy Me a Coffee: https://buymeacoffee.com/typicalskepticPatreon: https://patreon.com/typicalskepticPlease like, subscribe, share and turn on notifications. Your support helps independent conversations like this continue.If you value the work we're doing and are in a position to help, any support toward keeping the Typical Skeptic Podcast going would make a real difference right now. Never obligated—always deeply appreciated.

Dr. Jessica Ailani and Dr. Serena Orr discuss the genetic risk of migraine and post-traumatic headache in children.  Show citation:  Orr SL, Hershey AD, Kurowski BG, et al. Post-Traumatic Headache in Children and Genetic Risk of Migraine: An Observational Cohort Study. Neurol Genet. 2026;12(2):e200371. Published 2026 Apr 1. doi:10.1212/NXG.0000000000200371 

Patrick brings forward heartfelt Catholic parenting struggles and the friction that comes when faith meets indifference within families, then moves without pause to the weight of new abortion laws, exposing inconsistencies and pressing for the dignity of life with no hesitation. He weaves in humor as pronoun debates and denominational questions arise, tossing lightness and sharp inquiry in equal measure and never letting heavy topics linger unchallenged. Anna (email) - At what point should we decide to limit exposure to these family members so as not to scandalize our kids to believe that it's okay to be lukewarm Catholics and to even live a lifestyle that is contrary to Catholic beliefs? (01:40) George - The bill signed in MA yesterday allowing abortion up till birth. Horrendous and barbaric. Massachusetts House Passes Bill to Strengthen Abortion Care - https://malegislature.gov/PressRoom/Detail?pressReleaseId=1450 (14:32) Donna - When pregnant woman is killed in Maine, considered two people dead. Now, is the death of pregnant woman not two counts for murder? (18:55) Audio: Dr Levatino - Abortions are never for the health of the woman (21:42) Connie (email) - Last night while finishing up cleaning tasks at the dog shelter where I volunteer, another volunteer asked me my pronouns. Audio: Stephen A. Smith on WNBA not knowing what a woman is - https://x.com/VigilantFox/status/2086914175163330666/video/1?s=46 (35:46) Stephanie (email) - Genetic testing showed that my baby carried a genetic mutation, and I was told there could be a deformity, developmental delays, or even early childhood death due to underdevelopment. Abortion was discussed as an option. Today, I have an almost two-year-old, perfectly healthy baby girl. (38:30) Richard (email) – 15-week abortion ban- covering 95% of abortions- are not pro-life by any definition (42:42) Camille (email) - I hope we're not going to take a bunch of calls about hideous the abortion law in Massachusetts. Jennifer - Protestant friend claims denomination doesn't matter; Holy Spirit can never steer you wrong, so just listen to him. (46:59)

My next book, Productiveness, arrives this September. It's about the difference between doing more and doing what matters, and how we lost the ability to tell them apart. I'll send the release date the day it's set. Visit https://mikevardy.com/productiveness to learn more.This month's PM Talks starts with a confession: I've had an epiphany, and I don't use that word lightly. Somewhere between an "aha, I get it now" moment and what I can only describe as a holy moment is a distinction most of us never bother making — and once you start looking for the difference, you start noticing which of your own realizations actually deserved the weight you gave them.Patrick Rhone and I use this month's conversation to pull that distinction apart: the difference between a dawning recognition and a genuine unlocking, why holding an idea loosely lets it unfold instead of unravel, and how something as small as what his daughter calls a credit card turned into a real look at the nature-versus-nurture question neither of us can fully answer. I don't give away the specifics of the epiphany I'm sitting with this month — some things need more than one episode to explain — but the shape of it, and what to do with a moment like that once it arrives, is exactly what we get into.Six Discussion PointsAn "aha moment" is a small recognition — oh, I get it now — while a full epiphany carries a much heavier, more disorienting weight; treating every insight as the second kind burns you out.Real epiphanies tend to arrive with equal parts fear and fascination — the discomfort isn't a sign to back away, it's part of what makes the moment significant.Holding an idea loosely gives it room to unfold; gripping it tightly is what causes it to unravel instead — the difference between disassembling something on purpose and watching it fall apart.Genetic or predisposition information (like a cholesterol test result) doesn't eliminate the value of lifestyle choice — it just narrows the range you're actually choosing within.Big epiphanies rarely land once and disappear; they tend to keep resurfacing for days or weeks afterward, the way aftershocks follow an earthquake.The right response to a major realization is often reflection, not immediate action — sitting with it, journaling about it, letting it keep unfolding before trying to "do" anything with it.Three Connection PointsRead more from Patrick RhoneCatch up on past issues of The Lantern (and more)ProductivenessI'm not going to tell you what the epiphany was — not yet, anyway. What I will say is that if something's been quietly resurfacing in your own life for years without your noticing why, it might be worth sitting with it instead of trying to explain it away. Some things take six years to make sense. Give yours the same patience.Your inbox is a receiving dock, not a warehouse. Three moves, seconds a message, and only what needs you today is left standing. That's the promise of The 10 Second Inbox. Get it at https://mikevardy.com/10secondinbox today.

What's more British than the British royal family? More Spanish than the Spanish Monarchs? More Norse than the King of Norway? Well, a lot of things actually. In fact, nearly all of the 10 remaining hereditary monarchs of Europe have more German DNA than they do local. For centuries, royals almost exclusively married other, foreign royals. They rarely mixed their blue blood with people native to the Kingdoms they ruled over. What's more, when dynasties died out (often from excessive inbreeding) foreign royal houses put their own seconds sons on the throne, establishing new, entirely alien dynasties. Modern royal families try to brand themselves as throughly native and in touch with the common people. And if they ever spit into a test tube and sent it off for a DNA test, they would probably never publish the results. But, by looking back at their family trees, we can get a pretty good idea of their heritage. Last week we explore the heritage of the reigning families of Belgium, Denmark Liechtenstein, Luxembourg, Monaco and Norway. Today we'll analyze the DNA of the Dutch, Spanish, Swedish and British royal families. Plus we'll compare them all to see which modern monarchy has the most local DNA; and find out why the royals of Europe are all so German. Royal family of The Netherlands - Dutch royal family Royal family of Spain - Spanish Royal family Royal family of Sweden - Swedish royal family Royal family of The United Kingdom - British Royal family Why are the royals so German? Which royal families are the most German? Which royal families are the most local? Music: Brandenburg Concerto No4-1 BWV1049 - Classical Whimsical by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/ Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1100303 Artist: http://incompetech.com/ Join me every Tuesday when I'm Spilling the Tea on History! Check out my Youtube Channel: https://www.youtube.com/c/lindsayholiday Please consider supporting me at https://www.patreon.com/LindsayHoliday and help me make more fascinating episodes! Intro Music: Baroque Coffee House by Doug Maxwell #HistoryTeaTime #LindsayHoliday Please contact ⁠⁠⁠⁠⁠advertising@airwavemedia.com⁠⁠⁠⁠⁠ if you would like to advertise on this podcast. Learn more about your ad choices. Visit megaphone.fm/adchoices

Jason Coloma, CEO of South San Francisco-based Maze Therapeutics, on developing small molecule drugs based on human genetics for kidney diseases.

The Mad appleBetween August and early September, nature offers the eggplant, a vegetable with intense color and spongy flesh found in kitchens around the world. The eggplant (*Solanum melongena*) has a history as old as plant domestication, fascinating botanical characteristics, and culinary versatility that make it almost indispensable. Botanically speaking, the eggplant belongs to the Solanaceae family, alongside tomatoes, potatoes, and peppers. Although commonly considered a vegetable, its fruit is technically a berry. It originated in Asia—likely between India and Southeast Asia—and descends from wild, thorny, and bitter ancestors such as *Solanum insanum*. Genetic studies indicate that the eggplant was domesticated long ago; over time, selective breeding has reduced thorns, sweetened the flavor, and fostered the emergence of numerous shapes and colors. Varieties come in long and dark, round and purple, white, striped, and green forms. Each type possesses specific organoleptic qualities: long, dark purple varieties—such as the classic Neapolitan—have firm flesh and a delicate flavor, rendering them suitable for grilling or for making *parmigiana*. Round, violet varieties tend to become creamier after cooking and are ideal for sauces or fillings. White eggplants are generally less bitter and very tender.In contrast, green or striped varieties are distinguished by an especially sweet taste and thin skin, making them suitable for quick cooking or grilling. Choosing the right variety can enhance any recipe. In addition, the plant flourishes in warm, sunny conditions; in temperate zones, it is grown as an annual, whereas in milder climates, it can live longer. From there, the history of the eggplant becomes a tale of cultural spread and transformation. It has been cultivated in Asia for centuries and appears in ancient Chinese and Indian texts. It was later introduced to the Mediterranean region by the Arabs, who spread its cultivation starting in the Middle Ages. The Italian word *melanzana* derives from the Arabic bāinjān, having passed through Persian and other languages. Initially, the eggplant was not well-received in Europe; as a member of the nightshade family—which includes many toxic plants—it aroused suspicion.Some even called it the mad apple, fearing it would hurt the mind. Only over time, thanks to the spread of Mediterranean and Southern cuisines, did the eggplant become an integral part of culinary tradition. In Italy, in particular, it is the star of iconic dishes such as the ever-favorite parmigiana, the relish caponata, the Sicilian pasta alla Norma, sautéed eggplant, and stuffed eggplant. In the kitchen, selecting the right eggplant is important. It is best to choose firm specimens with smooth, glossy skin, free of bruises, and with a fresh green stem. If an eggplant is overripe, it will contain more seeds and have a more bitter taste. Traditionally, a salting process was used to draw out moisture: the eggplants were sliced, sprinkled with coarse salt, and left to drain for at least half an hour to remove some of the water and bitterness.Today, available varieties are less bitter, making this step not always necessary; however, it can be useful for reducing oil absorption or achieving a firmer texture. From selection to cooking, eggplant lends itself to numerous techniques. When grilled or griddled, slices acquire a smoky aroma and a tender texture; just a few minutes per side on a hot surface suffice, followed by seasoning with oil, garlic, mint, or parsley and a brief resting period. In the oven, they can be roasted whole—after being pricked—until the skin shrivels and the flesh becomes creamy, rendering them ideal for sauces, purees, or fillings. Alternatively, when sliced ​​or cubed and oven-baked, they require less oil than frying while still retaining an intense flavor. Full Content More Podcasts

With the Trump administration's newest political persecution of Anthony Fauci and three years after our first lab-leak special, now seemed like a useful time to return to the topic. Fortunately, you do not have to rely on our knowledge of viruses, as we have somehow managed to convince the same three esteemed virologists, Eddie Holmes, Kristian Andersen and Michael Worobey, to come back for an update.Mike, Kristian and Eddie return and offer us their read on where the scientific evidence on COVID's origins stands in 2026. They take us through the main lines of evidence and the often overlooked role of the wildlife trade, explaining why the lab-leak story remains so appealing, and how their own assessments have shifted as more evidence has emerged. We also discuss the standard claim that the media suppressed the lab-leak narrative while noting that coverage across both alternative and mainstream outlets remains heavily skewed towards it (and almost entirely detached from the research literature).Finally, we end on a characteristically positive note by discussing the Trump administration's attacks on science and the ongoing campaigns against high-profile scientists and public health figures. Our guests describe their experience of committing the heinous offence of following the scientific evidence and arriving at conclusions that contradict the preferred views of polemical politicians and prominent media pundits.In short, this episode is our modest attempt to drag the topic back towards the science, while also focusing on the price paid by the people who actually conduct the research and care about the evidence. We are not neutral when it comes to the ongoing attacks on science and scientists and do not pretend to be. LinksOur guests: Michael Worobey, Kristian Andersen, and Eddie HolmesOur previous interview with Worobey, Andersen and HolmesLab Leak Fever with Philipp MarkolinOur earlier interview with Stuart Neil on SARS-CoV-2Sam Harris, Alina Chan and Matt Ridley: Did SARS-CoV-2 Escape from a Lab?Bad Boy of Science: Is the COVID Lab Leak Hypothesis Dead?Kristian Andersen on his early emails, released messages and changing assessmentKristian Andersen's congressional testimony and document collectionKristian's thread responding to the use of his Slack messagesMichael Worobey on why his assessment changedWHO SAGO's 2025 assessment of the origins evidenceThe July 2026 Senate release of the Slack messagesKevin Drum's reading of the earlier Slack archiveThe current White House lab-leak pageThe July 2026 Fauci hearingNaomi Oreskes on scientific integrity and “ethical pessimism”Nature: Climate scientists report online attacksAlwine et al. on the harms to scientists, research and pandemic preparednessRelevant research papers and reviewsAndersen, K. G., Rambaut, A., Lipkin, W. I., Holmes, E. C., & Garry, R. F. (2020). The proximal origin of SARS-CoV-2. Nature Medicine, 26(4), 450–452.Crits-Christoph, A., Levy, J. I., Pekar, J. E., et al. (2024). Genetic tracing of market wildlife and viruses at the epicenter of the COVID-19 pandemic. Cell, 187(19), 5468–5482.Holmes, E. C. (2024). The emergence and evolution of SARS-CoV-2. Annual Review of Virology, 11(1), 21–42.Liu, W. J., Liu, P., Lei, W., et al. (2023). Surveillance of SARS-CoV-2 at the Huanan Seafood Market. Nature, 631(8020), 402–408.Pekar, J. E., Magee, A., Parker, E., et al. (2022). The molecular epidemiology of multiple zoonotic origins of SARS-CoV-2. Science, 377(6609), 960–966.Pekar, J. E., Moshiri, N., Lemey, P., et al. (2025). Recently reported SARS-CoV-2 genomes suggested to be intermediate between the two early main lineages are instead likely derived. Virus Evolution, 11(1).Pekar, J. E., Lytras, S., Ghafari, M., et al. (2025). The recency and geographical origins of the bat viruses ancestral to SARS-CoV and SARS-CoV-2. Cell, 188(12), 3167–3183.Temmam, S., Vongphayloth, K., Baquero, E., et al. (2022). Bat coronaviruses related to SARS-CoV-2 and infectious for human cells. Nature, 604

Dr. Jessica Ailani talks with Dr. Serena Orr about the genetic risk of migraine and post-traumatic headache in children.  Read the related article in Neurology®Genetics.  Disclosures can be found at Neurology.org. 

Morgan continues sharing her story (part 2 of 2) of life and grief and healing after a termination for medical reasons for a rare genetic disorder in her baby girl Collins.…Morgan shares how this podcast and the community has helped immensely throughout her grief and TFMR journey over the months since her loss.Living in Atlanta, Georgia, Morgan faced steep legal difficulties to obtain a termination at nearly 24 weeks gestation. Ultimately, the state of Georgia approved her case, and she underwent a termination at 23 weeks and 6 days at an abortion clinic. It was the worst day of her life.Since the death of her daughter, Morgan has been on a journey of learning how to survive unimaginable grief while still showing up as a mother to her living child, and also learning how to continue being a mother to Collins — honoring her, loving her, and carrying her, even though she is no longer earthside.Resources mentioned:Self-care guide: https://www.thetfmrdoula.com/tfmr-self-care.htmlMorgan's Instagram: www.instagram.com/morgan_love_11Morgan's email: bmorganlove@yahoo.comTo meet with Sabrina schedule your Connect Chat and find * your * way through with groups/1on1: http://www.thetfmrdoula.com/schedule-callAnd in this episode we invite you to join us in this space, just for TFMR parents:THE TFMR SUPPORT SANCTUARY‌If you're carrying the weight of your TFMR alone... you don't have to anymore.‌The TFMR Support Sanctuary: a monthly community for parents who want ways to release the shame, guilt, and despair of this loss and feel sure and seen in their motherhood, their parenthood, and the love they have for their baby.‌

Morgan Meaut shares her story of needing to terminate her wanted pregnancy for a rare genetic condition: 8p inverted duplication deletion syndrome, on the 23rd chromosome. Needing to make this decision for her baby girl Collins was one of the worst things she has ever been through.At the 20-week anatomy scan Morgan and her husband received the devastating news. The ultrasound showed severe swelling, ventriculomegaly and single cord. A follow up MRI of the brain showed missing corpus collosum in Collins' brainThis devastating diagnosis in pregnancy sent the couple on a four-week journey meeting with MFMs, genetic counselors, pediatric cardiologists, neurologists, and other specialists. Ultimately, through a genetic microarray they learned that Collins was worst case scenario. She had an extremely rare genetic condition: 8p inverted & duplication & deletion all on the 23rd chromosome. A very rare and large triple condition.Morgan was told that if Collins survived birth and infancy, she would be profoundly disabled — likely nonverbal, unable to live independently, and requiring lifelong full-time care.Morgan knew that was not the life they wanted for their baby.She was living in the state of Georgia at the time of her TFMR and had to pass a state board to approve the abortion.This is part 1 of 2 of Morgan's story where she shares how they made their decision to end their much wanted pregnancy.Morgan's Instagram: www.instagram.com/morgan_love_11Morgan's email: bmorganlove@yahoo.com....To meet with Sabrina schedule your Connect Chat and find * your * way through with groups/1on1: http://www.thetfmrdoula.com/schedule-callAnd in this episode we invite you to join us in this space, just for TFMR parents:THE TFMR SUPPORT SANCTUARY‌If you're carrying the weight of your TFMR alone... you don't have to anymore.‌The TFMR Support Sanctuary: a monthly community for parents who want ways to release the shame, guilt, and despair of this loss and feel sure and seen in their motherhood, their parenthood, and the love they have for their baby.‌

After a strong family history of breast cancer, GP Dr Camilla Stokholm turned to her own DNA for answers. She joins Liz and Dr Amy Walker to explore how understanding our genetic risk for disease empowers us to make lifestyle interventions before it has a chance to develop.They explain how unique genetic variations influence everything from nutrient absorption to oestrogen metabolism – and how this personalises our health journey.Camilla and Amy also share practical ways to dial down your risk of disease, from supporting gut health to eating more fibre, and why exercise, quality sleep and stress management are so powerful for ageing well. In this episode:· Why Camilla's family history of breast cancer led her to investigate her own genetic risk· Why there's no one-size-fits-all approach to health· How to align your lifestyle to your genetic code· Why standard blood tests don't give a full picture· It's not what you eat, but what you absorb· How chronic stress increases your nutrient requirements· How alcohol consumption impacts oestrogen production· Why low vitamin B12 levels may increase dementia risk· The importance of vitamin D for lowering your risk of disease· Why your genes determine how well you absorb and process nutrients· The importance of healthy bowel movements for clearing out toxins· Why a food-first approach to gut health beats supplements· How broccoli sprouts, leeks and garlic can help with oestrogen detoxification· Can cold plunges and saunas help protect against disease? Links mentioned in the episode:· Dawn Waldron's blog, Fluxable, on nutrition and lifestyle after cancer diagnosis· Lifecode GX genotype analysis – use code LIZLOVES for 10% off· Mosaic Medical cancer servicesMore from Camilla and Amy:· Follow Camilla on Instagram· Follow Amy on InstagramGet in touch with a question for Liz:· Email: podcast@lizearlewellbeing.com· WhatsApp: 07518 471 846More from Liz:· How To Age· A Better Second Half· Follow Liz on Instagram· Follow Liz Earle Wellbeing on InstagramHost: Liz EarleProducer: Anouszka Tate (Fresh Air Production) Content Writer: Lucy ParleyHead of Brand: Ellie SmithSome links may be affiliate links, which help support the show at no extra cost to you. Read our Affiliate Policy for more information. Hosted on Acast. See acast.com/privacy for more information.

Stay informed on current events, visit www.NaturalNews.com  - FDA's Approval of mRNA-Based Flu Shot (0:11) - Mechanism and Risks of mRNA Vaccines (3:56) - Impact on Elderly and Nutritional Deficiencies (7:33) - Historical Context and Ethical Concerns (11:01) - Depopulation Agenda and Genetic Integrity (20:27) - Survival Strategies and DNA Repair (27:06) - Energy Crisis and Water Scarcity (43:19) - Impact of Data Centers on Local Communities (61:34) - Competitive Escalation and Tax Incentives (64:28) - Public Health and Environmental Impact (70:29) - AMD's Impact on AI Performance and Market Potential (71:53) - Proposed AI Server and Legal Considerations (78:00) - Surveillance State and Data Center Expansion (81:33) - Water Consumption by Data Centers (85:28) - Local Community Action Against Data Centers (94:58) - Economic Bubble and Future of Data Centers (100:55) - Human Ingenuity and Decentralized Solutions (107:07) - Promotion of Above Phone and Brighteon AI (107:45) - Introduction to the UNA and Asset Protection (129:34) Watch more independent videos at http://www.brighteon.com/channel/hrreport  ▶️ Support our mission by shopping at the Health Ranger Store - https://www.healthrangerstore.com ▶️ Check out exclusive deals and special offers at https://rangerdeals.com ▶️ Sign up for our newsletter to stay informed: https://www.naturalnews.com/Readerregistration.html Watch more exclusive videos here:

Could lumping every type of Ehlers-Danlos syndrome under one umbrella actually be doing more harm than good? In this thought-provoking episode, host Dr. Linda Bluestein, the Hypermobility MD, is joined by Abbey Phillipson, who was born with COL5A1 classical Ehlers-Danlos syndrome, survived the first recorded non-traumatic pediatric spondyloptosis, and now serves as Head Strength Coach for Paralympic and Adaptive Sports at the University of Michigan and founder of the Collagen Advocacy Network. Inspired by Abbey's powerful presentation at the UVA Research Symposium, this conversation challenges long-held assumptions about how we define, discuss, and advocate for Ehlers-Danlos syndrome. Although hypermobile EDS has dramatically increased public awareness, Abbey argues that people living with rare and ultra-rare EDS types, representing just 1 to 3 percent of the community, are too often overlooked in research, funding, clinical care, and even public conversations. Together, Dr. Bluestein and Abbey explore whether the different EDS types should continue to share a single name, why distinguishing hypermobile EDS from the genetically defined types could ultimately benefit everyone, and how naming disorders by their underlying gene and predominant manifestation might improve diagnosis, research, and patient care. Abbey also shares deeply personal stories that illustrate what's at stake, including a friend who spent 35 years carrying the wrong diagnosis before genetic testing revealed kyphoscoliotic EDS. Their conversation highlights why genetic counseling matters, the limitations of direct-to-consumer testing, and how assumptions in medicine can unintentionally delay appropriate care. The episode closes on a message of hope and empowerment. After her neurosurgeon prescribed strength training, Abbey transformed from experiencing monthly full-joint dislocations to having none. Today, she helps athletes and people of all abilities discover that movement can be adapted, strength can be built, and disability does not define potential. She also shares why advocacy is most effective when it channels frustration into meaningful, solution-focused action, plus one of her favorite protein-packed hypermobility hacks. Takeaways: People with rare and ultra-rare EDS types make up only about 1 to 3 percent of the community and are frequently left out of decisions about research, funding, and care. Clearly distinguishing hypermobile EDS from the genetically defined types benefits everyone; naming a condition by its gene and predominant manifestation could improve medical clarity and care. The "invisible illness" framing can cause genuinely visible rare types to be overlooked, and comfort with a clinical diagnosis can lead to decades-long misdiagnoses that genetic testing would catch. Genetic testing and counseling are essential, especially before starting a family; direct-to-consumer testing carries real limitations and should be interpreted cautiously. Strength training can be transformative: after her neurosurgeon prescribed it, Abbey went from frequent full dislocations to none, and movement can be tailored to activities people love rather than being purely prescriptive. Go to AirDoctorPro.com and use promo code BENDY_ to get UP TO $300 off today! Want more Abbey Phillipson? Instagram: @abbeyphillipson @definedbycollagen Website: collagenadvocacynetwork.org Want more Dr. Linda Bluestein, MD?Website:  https://www.hypermobilitymd.com/YouTube: https://www.youtube.com/@bendybodiespodcastInstagram: ⁠⁠⁠⁠https://www.instagram.com/hypermobilitymd/⁠⁠⁠⁠Facebook: ⁠⁠⁠⁠https://www.facebook.com/BendyBodiesPodcast⁠⁠⁠⁠X: ⁠⁠⁠⁠https://twitter.com/BluesteinLinda⁠⁠⁠⁠LinkedIn: ⁠⁠⁠⁠https://www.linkedin.com/in/hypermobilitymd/⁠⁠⁠⁠Newsletter: ⁠⁠⁠⁠https://hypermobilitymd.substack.com/Shop my Amazon store ⁠⁠⁠ https://www.amazon.com/shop/hypermobilitymdDr. Bluestein's Recommended Herbs, Supplements and Care Necessities: https://us.fullscript.com/welcome/hypermobilitymd/store-start Want to learn more about the UVA EDS Center? For Appointments and Questions: RUVAEDSCenter@uvahealth.orgUVA EDS: https://www.uvahealth.com/healthy-practice/advancing-care-through-ehlers-danlos-clinicUVA EDS FAQ: https://www.uvahealth.com/support/eds/faq UVA Pediatric Integrative Medicine: https://childrens.uvahealth.com/specialties/integrative-health Thank YOU so much for tuning in. We hope you found this episode informative, inspiring, useful, validating, and enjoyable. Join us on the next episode for YOUR time to level up your knowledge about hypermobility disorders and the people who have them. YOUR bendy body is our highest priority!⁠⁠ Learn more about Human Content at ⁠⁠⁠http://www.human-content.com⁠⁠⁠ Podcast Advertising/Business Inquiries: ⁠⁠⁠sales@human-content.com⁠⁠⁠ Part of the Human Content Podcast Network FTC: This video is not sponsored. Links are commissionable, meaning I may earn commission from purchases made through links Join YOUR Bendy Bodies community at ⁠⁠https://www.bendybodiespodcast.com/⁠⁠. Learn more about your ad choices. Visit megaphone.fm/adchoices

Could lumping every type of Ehlers-Danlos syndrome under one umbrella actually be doing more harm than good? In this thought-provoking episode, host Dr. Linda Bluestein, the Hypermobility MD, is joined by Abbey Phillipson, who was born with COL5A1 classical Ehlers-Danlos syndrome, survived the first recorded non-traumatic pediatric spondyloptosis, and now serves as Head Strength Coach for Paralympic and Adaptive Sports at the University of Michigan and founder of the Collagen Advocacy Network. Inspired by Abbey's powerful presentation at the UVA Research Symposium, this conversation challenges long-held assumptions about how we define, discuss, and advocate for Ehlers-Danlos syndrome. Although hypermobile EDS has dramatically increased public awareness, Abbey argues that people living with rare and ultra-rare EDS types, representing just 1 to 3 percent of the community, are too often overlooked in research, funding, clinical care, and even public conversations. Together, Dr. Bluestein and Abbey explore whether the different EDS types should continue to share a single name, why distinguishing hypermobile EDS from the genetically defined types could ultimately benefit everyone, and how naming disorders by their underlying gene and predominant manifestation might improve diagnosis, research, and patient care. Abbey also shares deeply personal stories that illustrate what's at stake, including a friend who spent 35 years carrying the wrong diagnosis before genetic testing revealed kyphoscoliotic EDS. Their conversation highlights why genetic counseling matters, the limitations of direct-to-consumer testing, and how assumptions in medicine can unintentionally delay appropriate care. The episode closes on a message of hope and empowerment. After her neurosurgeon prescribed strength training, Abbey transformed from experiencing monthly full-joint dislocations to having none. Today, she helps athletes and people of all abilities discover that movement can be adapted, strength can be built, and disability does not define potential. She also shares why advocacy is most effective when it channels frustration into meaningful, solution-focused action, plus one of her favorite protein-packed hypermobility hacks. Takeaways: People with rare and ultra-rare EDS types make up only about 1 to 3 percent of the community and are frequently left out of decisions about research, funding, and care. Clearly distinguishing hypermobile EDS from the genetically defined types benefits everyone; naming a condition by its gene and predominant manifestation could improve medical clarity and care. The "invisible illness" framing can cause genuinely visible rare types to be overlooked, and comfort with a clinical diagnosis can lead to decades-long misdiagnoses that genetic testing would catch. Genetic testing and counseling are essential, especially before starting a family; direct-to-consumer testing carries real limitations and should be interpreted cautiously. Strength training can be transformative: after her neurosurgeon prescribed it, Abbey went from frequent full dislocations to none, and movement can be tailored to activities people love rather than being purely prescriptive. Go to AirDoctorPro.com and use promo code BENDY_ to get UP TO $300 off today! Want more Abbey Phillipson? Instagram: @abbeyphillipson @definedbycollagen Website: collagenadvocacynetwork.org Want more Dr. Linda Bluestein, MD?Website:  https://www.hypermobilitymd.com/YouTube: https://www.youtube.com/@bendybodiespodcastInstagram: ⁠⁠⁠⁠https://www.instagram.com/hypermobilitymd/⁠⁠⁠⁠Facebook: ⁠⁠⁠⁠https://www.facebook.com/BendyBodiesPodcast⁠⁠⁠⁠X: ⁠⁠⁠⁠https://twitter.com/BluesteinLinda⁠⁠⁠⁠LinkedIn: ⁠⁠⁠⁠https://www.linkedin.com/in/hypermobilitymd/⁠⁠⁠⁠Newsletter: ⁠⁠⁠⁠https://hypermobilitymd.substack.com/Shop my Amazon store ⁠⁠⁠ https://www.amazon.com/shop/hypermobilitymdDr. Bluestein's Recommended Herbs, Supplements and Care Necessities: https://us.fullscript.com/welcome/hypermobilitymd/store-start Want to learn more about the UVA EDS Center? For Appointments and Questions: RUVAEDSCenter@uvahealth.orgUVA EDS: https://www.uvahealth.com/healthy-practice/advancing-care-through-ehlers-danlos-clinicUVA EDS FAQ: https://www.uvahealth.com/support/eds/faq UVA Pediatric Integrative Medicine: https://childrens.uvahealth.com/specialties/integrative-health Thank YOU so much for tuning in. We hope you found this episode informative, inspiring, useful, validating, and enjoyable. Join us on the next episode for YOUR time to level up your knowledge about hypermobility disorders and the people who have them. YOUR bendy body is our highest priority!⁠⁠ Learn more about Human Content at ⁠⁠⁠http://www.human-content.com⁠⁠⁠ Podcast Advertising/Business Inquiries: ⁠⁠⁠sales@human-content.com⁠⁠⁠ Part of the Human Content Podcast Network FTC: This video is not sponsored. Links are commissionable, meaning I may earn commission from purchases made through links Join YOUR Bendy Bodies community at ⁠⁠https://www.bendybodiespodcast.com/⁠⁠. Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of the Always Better Than Yesterday Podcast, host Ryan Hartley welcomes back cell biologist and bestselling author Dr Bruce Lipton for a conversation centred on his new book, Beyond Darwin: How Epigenetics, Quantum Science, and Cooperation Shape Humanity's Future.Bruce opens with a stark warning: our present civilisation is not sustainable. Humanity is consuming beyond the resources of one planet, damaging the web of life and continuing to operate through systems built upon competition, separation and survival.At the centre of the conversation is Bruce's challenge to the cultural interpretation of Darwinian evolution. He argues that “survival of the fittest” has programmed civilisation to see life as a struggle and other people as competitors. His alternative theory of conscious evolution draws together epigenetics, quantum science and fractal geometry, presenting cooperation rather than competition as life's true evolutionary strategy. Those with ears, let them hear.Always love,RyanThis episode is not medical advice.About Beyond DarwinBeyond Darwin: How Epigenetics, Quantum Science, and Cooperation Shape Humanity's Future is written by Bruce H. Lipton, PhD, with Patricia King.Bruce presents a unified theory of conscious evolution built upon three fields that were unavailable to Darwin: epigenetics, quantum physics and fractal geometry. The book challenges the idea that competition is evolution's essential survival mechanism and instead presents cooperation, environmental responsiveness and expanding consciousness as the pathway forwards.It positions contemporary global chaos as the cocoon stage of an evolutionary process: a necessary breakdown through which a more advanced and cooperative civilisation may emerge. Bruce describes the work not only as an alternative theory of evolution, but as a blueprint for igniting that change. The book is due for release on 18 August 2026. Connect with Dr Bruce LiptonOfficial website: https://www.brucelipton.com/Beyond Darwin: https://www.brucelipton.com/books/beyond-darwin/Instagram: https://www.instagram.com/brucelipton/YouTube: https://www.youtube.com/user/biologyofbeliefFacebook: https://www.facebook.com/BruceHLiptonPhD/See Bruce in the UKManchester, 25 November 2026:https://tcche.org/event/bruce-lipton-beyond-darwin-manchester-2026/London, 28 November 2026:https://tcche.org/event/bruce-lipton-beyond-darwin-london-2026/Connect with Always Better Than YesterdayWebsite: https://abty.co.uk/Instagram: https://www.instagram.com/alwaysbetterthanyesterdayuk/LinkedIn: https://www.linkedin.com/company/abty/Join our mailing list: https://abty.co.uk/contactExplore ABTY coaching: https://abty.co.uk/coachingPlease email questions and reflections to: podcast@abty.co.ukEpisode Chapters00:00 – Welcome back, Dr Bruce Lipton00:43 – Why civilisation is unsustainable02:18 – Dedicating Beyond Darwin to Mother Nature04:38 – Self-love and our relationship with the world05:23 – Genetic determinism and programmed victimhood11:40 – How “survival of the fittest” shaped civilisation14:37 – Darwin was wrong15:54 – Cooperation, the garden and evolutionary harmony18:16 – The personal cost of challenging scientific orthodoxy19:26 – Personal beliefs create lives; shared beliefs create civilisation23:03 – Changing the subconscious programme27:22 – Evolution and the creation of heaven on Earth28:19 – How power evolved32:31 – Programming, Mother Nature and the feminine42:37 – Restoring masculine and feminine harmony46:08 – Humanity's great metamorphosis48:52 – From the mess to the butterfly55:19 – Must humanity consciously create the future?57:40 – Quantum science, energy and spirituality01:02:46 – Creation and evolution belong together01:05:16 – Why Beyond Darwin matters now01:05:54 – You were born into heaven

In this episode of The Poultry Nutrition Blackbelt Podcast, Dr. Sandro Cerrate, Poultry Nutrition Consultant at Credinser LLC, explains practical strategies to improve broiler breeder and layer performance through feather scoring, body condition assessment, nutrient optimization, and mycotoxin management. He also shares field experiences from poultry operations across multiple countries and discusses data-driven decision-making. Listen now on all major platforms!"The best recommendation for breeders is to measure and monitor feed and body condition regularly to ensure long-term production success."Meet the guest: Dr. Sandro Cerrate earned his PhD in Poultry Nutrition from the University of Arkansas after completing his bachelor's and master's degrees in Animal Sciences and Animal Nutrition at the National Agrarian University. Following research and industry roles, he became an independent Poultry Nutrition Consultant serving clients worldwide. Listen to The Poultry Nutrition Blackbelt Podcast with Dr. Sandro Cerrate on all major platforms.Liked this one? Don't stop now — Here's what we think you'll love!What you'll learn:(00:00) Highlight(01:43) Introduction(02:19) Broiler breeder nutrition(03:43) Genetic selection and body condition(06:28) Addressing mycotoxins in feed(09:22) Alternative feed additives(11:51) Advice for broiler breeders(15:10) Closing thoughtsThe Poultry Nutrition Blackbelt Podcast is trusted and supported by innovative companies like:* Fortiva* Kemin- DietForge- Anitox- Poultry Science Association

What's more British than the British royal family? More Spanish than the Spanish Monarchs? More Norse than the King of Norway? Well, a lot of things actually. In fact, nearly all of the 10 remaining hereditary monarchs of Europe have more German DNA than they do local. For centuries, royals almost exclusively married other, foreign royals. They rarely mixed their blue blood with people native to the Kingdoms they ruled over. What's more, when dynasties died out (often from excessive inbreeding) foreign royal houses put their own seconds sons on the throne, establishing new, entirely alien dynasties. Modern royal families try to brand themselves as throughly native and in touch with the common people. And if they ever spit into a test tube and sent it off for a DNA test, they would probably never publish the results. But, by looking back at their family trees, we can get a pretty good idea of their heritage. So let's find out just when and how the Swedish got so French, the Dutch got Argentinian, and everyone got so German! Royal family of Belgium Royal family of Denmark Princely family of Liechtenstein Grand Ducal family of Luxembourg Princely family of Monaco Royal family of Norway Please consider supporting me at https://www.patreon.com/LindsayHoliday Music: Brandenburg Concerto No4-1 BWV1049 - Classical Whimsical by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/ Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1100303 Artist: http://incompetech.com/ Join me every Tuesday when I'm Spilling the Tea on History! Check out my Youtube Channel: https://www.youtube.com/c/lindsayholiday Please consider supporting me at https://www.patreon.com/LindsayHoliday and help me make more fascinating episodes! Intro Music: Baroque Coffee House by Doug Maxwell #HistoryTeaTime #LindsayHoliday Please contact ⁠⁠⁠⁠⁠advertising@airwavemedia.com⁠⁠⁠⁠⁠ if you would like to advertise on this podcast. Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr. Mike Van Amburgh begins by outlining how amino acid nutrition has historically been viewed almost exclusively through the lens of milk protein. He explains that emerging research clearly shows amino acids play far broader roles in the cow, influencing milk fat synthesis, energy metabolism, and overall efficiency. As genetic potential has increased, amino acids are now supporting many biological pathways beyond simple milk protein yield. (05:50)  Dr. Van Amburgh explains that dairy systems across Europe and North America are under increasing pressure to reduce nitrogen losses. By formulating more precise diets that better match amino acid requirements, cows can excrete significantly less urinary nitrogen while maintaining—or even improving—milk production, creating both environmental and economic benefits. (09:30)  The panel discusses the robustness of current CNCPS model libraries and explains why forage amino acid profiles tend to be relatively conserved. While management factors like heat damage or poor fermentation can alter availability, microbial protein ultimately supplies a large and consistent portion of metabolizable amino acids to the cow. (12:15)  Dr. Van Amburgh emphasizes that microbial protein should supply roughly half of total amino acid needs, making rumen efficiency critical. However, as production levels rise, microbial protein alone is no longer sufficient creating a clear role for rumen‑protected amino acids to close growing nutritional gaps. (16:20)  Dr. Usman Arshad then leads a deep discussion on choline and methionine in transition cows. He explains why these two nutrients are not interchangeable, despite both acting as methyl donors. Choline has a unique lipotropic role in supporting liver fat export and reducing fatty liver risk during early lactation, while methionine primarily supports milk production and protein synthesis. Research shows that choline supplementation during the transition period alone can generate lasting carryover improvements in milk yield later in lactation. (29:00)  The panel addresses a common industry question: how much choline is enough? Dr. Arshad reviews decades of research, including meta‑analyses showing a largely linear response between choline ion intake and milk production. While 12–13 g/day of choline ion remains, the standard recommendation based on most available studies, data suggest additional benefits may exist at higher levels—even though more research is still needed. (34:00)  Dr. Van Amburgh explains that recent infusion and feeding studies demonstrate much higher metabolizable protein requirements than traditionally assumed, driven in part by the important role of non‑essential amino acids. These nutrients support energy generation, glucose synthesis, and tissue metabolism during early lactation—contributing to substantial gains in energy‑corrected milk when requirements are met. (44:30)  The panel also discusses whether amino acid balancing can help cows cope with heat stress. While amino acids do not eliminate heat stress, improving metabolic efficiency appears to reduce wasted heat production and support immune function and gut integrity, potentially helping cows better navigate stressful conditions. (54:45)  The group shares real‑world examples showing that improving amino acid balance often increases milk components without increasing intake, frequently delivering returns of 2:1 or greater, depending on milk pricing and market structure. (58:00)  Dr. Van Amburgh then offers candid insights into rumen‑protected amino acid bioavailability, explaining that products on the market are not created equal. Independent testing has shown efficiencies ranging from as low as ~10% to as high as ~80%. The panel stresses that transparent, published bioavailability data are essential for accurate formulation and for maintaining credibility across the industry. (01:01:30)  Lastly, the panel examines modern high‑starch diets, monensin use, and intake regulation. Dr. Van Amburgh suggests many systems may now be producing excessive propionate, potentially limiting intake through chemical fill. He argues that rebalancing starch and NDF—rather than simply adding more concentrate—may unlock better efficiency and performance. (01:10:00)  The episode concludes with final audience questions. (01:20:29)  Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table. If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

Could your weight gain and non-stop thoughts about food actually come from a rare condition you were born with? In this episode of the Docs Who Lift podcast, Dr. Spencer Nadolsky and Dr. Karl Nadolsky chat with weight expert Dr. Jesse Richards about Bardet-Biedl Syndrome (BBS). This rare condition tricks your brain into thinking your body is starving, even when you have plenty of body fat stored up. They talk about how doctors figure out if someone has BBS, an easy math trick to check your risk, and why normal diets or standard weight-loss shots do not always work for this condition. Plus, you will learn about special medicines that fix the brain's hunger signals when nothing else seems to work! In This Episode, You Will Learn: What Bardet-Biedl Syndrome (BBS) is and why many doctors miss it. Clear physical signs to look for, like extra fingers or toes, vision loss, and weight gain that starts very early in life. An easy formula to check your risk using your weight and your daily thoughts about food. The big difference between normal food cravings and extreme, non-stop hunger. Why special medicines can fix brain signals when regular weight-loss tools fail. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

On the same day in July, three different FBI sources gave three different answers about the single most critical piece of evidence in the Nancy Guthrie kidnapping — whether the ransom notes are even real. Tony Brueski goes live to walk through the contradiction: Reuters reporting all the notes are fake, the Phoenix field office saying some may be legitimate, and TMZ's sources ranking the original two as more credible than not. Same evidence, same day, three different stories from inside one investigation. It landed the same week Savannah Guthrie posted a video to her mother's abductor that dropped every demand she'd made for six months and replaced them with something that sounded like she already knows how this ends. Retired FBI Special Agent Jennifer Coffindaffer joins the conversation with her ten-point challenge to investigators — why the enhanced photo of porch guy has never been released, why Nancy's face is on the billboards instead of a suspect's, and the one question nobody has answered yet. Former agent Steve Moore has already called the case cold on camera, predicting fresh eyes will eventually have to rotate in. Genetic genealogy testing on DNA recovered from inside the house began in February. Five months later, if results exist, nobody has shared them. This is a live conversation about what it means when the Bureau can't agree with itself, and a daughter's words move on without them. Links Join Our SubStack For AD-FREE ADVANCE EPISODES & EXTRAS!: https://hiddenkillers.substack.com/ Want to comment and watch this podcast as a video? Check out our YouTube Channel. https://www.youtube.com/channel/UC8-vxmbhTxxG10sO1izODJg?sub_confirmation=1 Instagram https://www.instagram.com/hiddenkillerspod/ Facebook https://www.facebook.com/hiddenkillerspod/ Tik-Tok https://www.tiktok.com/@hiddenkillerspod X Twitter https://x.com/TrueCrimePod This publication contains commentary and opinion based on publicly available information. All individuals are presumed innocent until proven guilty in a court of law. Nothing published here should be taken as a statement of fact, health or legal advice. Hashtags #NancyGuthrie #FBI #HiddenKillersLive #TrueCrime #JenniferCoffindaffer #Tucson #PorchGuy #RansomNotes #PimaCounty #ColdCase 

Tayne, host of the Tayne Talks podcast, joins me to talk about McBee Dynasty Season 3 Episodes 1-5! Full episode available on Patreon! CLICK HERE TO LISTEN TO THE REST! ACCESS AD-FREE, BONUS AND VIDEO EPISODES BY BECOMING A PATRON HERE⁠⁠⁠⁠ Subscribe to my ⁠YouTube⁠!! Follow Tayne on⁠⁠⁠ ⁠Instagram⁠⁠⁠⁠ and listen to her⁠⁠⁠ ⁠podcast⁠⁠⁠ Follow me on⁠⁠⁠⁠ ⁠Instagram⁠⁠⁠⁠⁠ ⁠Support the show⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

After a summer hiatus, David Brown returns to Angus Underground with longtime friend and repeat guest Dave Mullins for a candid conversation about the current Angus business, the cattle market, and the opportunities facing breeders today. David opens with updates from Montana Ranch before diving into his thoughts on the American Angus Association's Data Driven Herd recognition program, the importance of submitting real-world performance data, and recent changes surrounding genetic testing and AI certificate requirements. While never shy about sharing his frustrations, David's larger message remains consistent: meaningful data collection matters, particularly as genomics continue to play a larger role in cattle evaluation. From there, David and Dave turn to what they describe as an unprecedented cattle market. Despite drought conditions, market volatility, and challenges such as New World screwworm concerns, demand for quality Angus genetics remains remarkably strong. They examine why traditional “sale seasons” are becoming less relevant, with successful production and frozen genetics sales happening throughout the year. Dave explains that today's buyers are increasingly willing to invest whenever the right genetics become available—whether they're looking for embryos for an upcoming IVF cycle, a donor cow to advance their program, or genetics that fit a very specific breeding philosophy. Ultimately, the conversation centers on intentionality. David and Dave encourage breeders to determine exactly what they want their program to accomplish, reverse engineer the path to get there, and resist being distracted by industry noise or someone else's definition of success. Whether a breeder focuses on maternal cattle, performance genetics, carcass traits, show cattle, or another segment entirely, there is room within the Angus breed for different approaches. Their message to both established and young producers is simple: build a good product, communicate clearly why it matters, understand your customer, and become exceptionally good at serving your particular segment of the cattle business. Key Discussion Points The return of Angus Underground after a busy summer at Montana Ranch American Angus Association's Data Driven Herd recognition program Why real-world performance data remains important alongside genomics Genetic defect testing and AI certificate requirements Current cattle inventory and historically strong market conditions New World screwworm concerns and cattle-market volatility Record demand for registered Angus cattle and genetics Why traditional spring and fall “sale seasons” are changing Growing opportunities for year-round embryo and semen sales How IVF has changed the timing of frozen-genetics purchases The diversity of today's Angus breeders and buyers Finding the right customer instead of trying to appeal to everyone Building a breeding program around intentionality and consistency “Reverse engineering” your operation from the outcome you want Why breeders should learn from successful programs—even those with completely different philosophies Opportunities for young people looking to build careers in the cattle industry  

Send us Fan MailThis week we're diving into Deep Blue Sea (1999). We look back on its stacked cast, dissect its balance of creature-feature and ethical sci-fi horror, and debate how its shark approach holds up against the Jaws legacy. This episode contains spoilers, beginning at 21:57.Mentioned in the EpisodeWatch the MovieDeep Blue Sea (1999)Related Episodes⁠024: Scream (1996)⁠097: Alien (1979)⁠162: Jaws 2 (1978)⁠222: Jaws 3-D (1983)⁠279: Jaws: The Revenge (1987)⁠416: Halloween H20: 20 Years Later (1998)Sharksploitation: 50 Years After Jaws (Video)Sharksploitation: 50 Years After Jaws (Episode)Main Episode⁠Sharksploitation: How Jaws Changed Horror and Shark Movies Forever⁠Deepest Bluest (Shark's Fin)⁠How Deep Blue Sea's Most Shocking Death Was Created⁠Cutthroat Island (1995)⁠The Long Kiss Goodnight (1996)⁠Star Wars: Episode I – The Phantom Menace (1999)⁠Sharknado (2013)⁠Frankenstein (1931)⁠Open Water (2003)⁠Piranha (1978)⁠Halloween: Resurrection (2002)⁠Dangerous Animals (2025)⁠Genetic engineering⁠Animal testing⁠Alzheimer's diseaseSupport the showThanks for listening to Hack or Slash! Want more from the show? Join us on Patreon for extended episodes, bonus reviews, B-sides, watchalongs, behind-the-scenes extras, and more ways to help keep the show alive and slashing.Support us on PatreonYou can also hang out with us between episodes in our community spaces. Join the Discord for watch parties, episode discussions, horror recommendations, and general spooky nonsense.Join our DiscordFollow Hack or Slash:WebsiteYouTubeRedditInstagramTikTokHave thoughts on this week's movie? Leave a comment, send us a voicemail, or tag us online. We love hearing your thoughts on the movies we cover.Happy slashing!Music Credits: "Hack or Slash" by Daniel Stapleton

In this episode the guys sit down with IFBB pro bodybuilder and science-driven performance coach Ben Pakulski for a wide-ranging conversation on peptides, performance, identity and the hard lessons of a 20-year bodybuilding career. Ben breaks down the peptide landscape — why he's optimistic about the science but deeply cautious about sourcing (90%+ of research peptides come from China with no quality guarantees), the most exciting peptides he's currently working with including SS-31 for mitochondrial repair, and myostatin inhibition and where the science actually stands. They also cover Ben's origin story — going from 160 pounds at 17 to 240 by 19 purely naturally, getting cut from a baseball team at 12 and how that shaped everything, the culture of his Toronto gym and what hard training actually looks like, the Arnold Classic story where he competed sick all night with vomiting and diarrhea and still got second. Ben shares how bodybuilding was never his identity — just something he did — and why leaving the sport felt like relief rather than loss. They also dig into GLP-1 use, the looming frailty epidemic, genetic testing for coaching, why the guys fixed their training plateaus through gut health and hormone optimization, and why Ben thinks the hard work of getting fit is the actual prize — not the physique.   MAPS Upper Lower: https://mapsupperlower.com Code: LAUNCH for 40% off. Two days left on this offer. Four day split, male and female versions, workout videos and live coaching with Cole.   SPONSORS Ketone IQ: https://ketone.com/MINDPUMP 30% off subscription orders plus a free gift with your second shipment. Also available at Target stores nationwide.   GUEST LINKS Ben Pakulski: https://www.benpakulski.com Ben's Podcast — Muscle Intelligence: available on all major platforms Instagram: @bpakfitness   LINKS Mind Pump Store: https://mindpumpstore.com Maps Fitness Products: https://mapsfitnessproducts.com Instagram: @mindpumpmedia 0:00 - Intro 1:58 - The peptide landscape — incredible potential, serious sourcing risk 5:14 - SS-31 for mitochondrial repair and why Ben's dad is on 10mg three times a week 9:04 - Mots-C vs SS-31 — why people respond differently and what might explain it 10:17 - Myostatin inhibition — what the science actually says about building muscle without training 13:32 - Gene therapy for myostatin in Mexico and what Ben's friends actually reported 15:28 - Why putting on muscle through shortcuts doesn't build confidence — only the process does 17:54 - Why physical stress and psychological stress are disconnected in modern life — and why that matters 22:05 - Getting cut from a baseball team at 12 and how that shaped everything 24:06 - The four master skills Ben teaches his kids — body, finances, communication, emotions 25:51 - How Ben transitioned out of pro bodybuilding without an identity crisis 28:58 - Going from 160 to 230 pounds naturally at 17 — the real story 33:01 - Getting a Muscle Tech contract at 19 by just walking around a show 38:03 - Training culture at Gold's Venice vs his Toronto gym — what hard work actually looks like 43:36 - Why headphones in the gym killed community — and why CrossFit understood something bodybuilding missed 48:24 - The Arnold Classic sick story — vomiting all night, competing anyway, getting second 55:28 - First steroid cycle at 19 and what it actually did 1:02:43 - How Ben's business pivoted through Covid and why coaching replaced digital programs 1:06:32 - Warrior and monk — how Ben learned to wield intensity as a tool rather than let it control him 1:13:06 - GLP-1 use in bodybuilding, the looming frailty epidemic and the gut motility problem 1:23:07 - Genetic testing for coaching — seeing constraints before clients hit them 1:31:05 - Sal's gut health and testosterone story — 15 pounds of muscle from a parasite cleanse

Stay informed on current events, visit www.NaturalNews.com  - Fauci's Depopulation Agenda and Biological Weapons (0:10) - Government Lies and Radiation Risks (4:31) - Fauci's Testimony and Fifth Amendment Invocation (11:48) - Trump's Role in the Depopulation Agenda (23:33) - The Depopulation Agenda and the Role of the Military (1:03:35) - The Impact of Nuclear War on Humanity (1:03:47) - The Role of AI and the Future of Humanity (1:03:59) - The Global Energy War and Its Consequences (1:05:31) - The Role of Technology in Survival (1:05:44) - The Importance of Self-Reliance and Preparedness (1:13:36) - Europe's Economic Collapse and Geopolitical Tensions (1:15:34) - The Role of Young Men in the Conflict (1:22:02) - The Impact of Nuclear War and COVID-19 Vaccines (1:25:56) - The Future of Humanity and Technological Advancements (1:33:01) - Preparedness and Survival Strategies (1:39:56) - The Role of Local Law Enforcement and Community Support (1:40:11) - The Ethics of Self-Defense and Protecting the Innocent (1:41:08) - The Importance of Training and Skill Development (1:49:26) - The Role of Technology and AI in the Future (1:49:40) - Final Thoughts and Call to Action (1:50:37) Watch more independent videos at http://www.brighteon.com/channel/hrreport  ▶️ Support our mission by shopping at the Health Ranger Store - https://www.healthrangerstore.com ▶️ Check out exclusive deals and special offers at https://rangerdeals.com ▶️ Sign up for our newsletter to stay informed: https://www.naturalnews.com/Readerregistration.html Watch more exclusive videos here:

In this conversation, Dr. Gladden and Annelie Smith explore the intersection of genetics and nutrition, emphasizing the importance of personalized approaches to health. They discuss the evolution of nutrigenomics, the role of AI in developing tailored health plans, and the complexities of hormonal balance as influenced by genetics. Annelie shares insights from her clinical experience, highlighting the need for a systems biology approach to understand the intricate relationships between genes, hormones, and overall health. The discussion also touches on future directions in genetic testing and the potential for more accessible and actionable insights for individuals. In this conversation, Dr. Gladden and Annelie Smith delve into the complexities of hormone replacement therapy, emphasizing the importance of understanding hormonal pathways and the role of genetics. They discuss how stress impacts hormonal balance and the significance of reprogramming the nervous system for better health outcomes. The conversation also highlights the relevance of nutrigenomics in personalized nutrition and the powerful benefits of sulforaphane. Finally, they explore the value of genetic testing for optimizing health and wellness.   For Audience Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now   Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/!    Takeaways ·       Nutrigenomics provides insights into personalized nutrition. ·       Understanding genetics can enhance dietary recommendations. ·       AI is transforming the landscape of personalized medicine. ·       Systems biology offers a holistic view of health. ·       Patient engagement is key to successful health interventions. ·       Genetic testing can reveal vulnerabilities in health. ·       Hormonal balance is influenced by genetic factors. ·       Personalized health plans can improve patient outcomes. ·       The future of genetics holds promise for broader applications. ·       Access to genetic information can empower individuals. Hormone replacement therapy is complex and requires a systems approach. ·       Understanding genetic pathways is crucial for effective hormone management. ·       Stress significantly impacts hormonal balance and overall health. ·       Reprogramming the nervous system can alleviate stress and improve health. ·       Nutrigenomics plays a vital role in personalized nutrition. ·       Sulforaphane is a powerful compound with numerous health benefits. ·       Diet should be tailored to the individual, not a one-size-fits-all approach. ·       Genetic testing provides valuable insights for health optimization. ·       Managing stress involves rebuilding mental constructs that generate it. ·       Investing in genetic testing is a one-time opportunity with lasting benefits.    Chapters 00:00 Introduction to Nutrigenomics and Personalization 02:49 The Role of Genetics in Nutrition 06:01 Systems Biology Approach to Health 08:55 AI in Nutrigenomics and Personalized Medicine 11:51 Case Study: Hormonal Balance and Genetics 14:59 Future Directions in Genetics and Health 23:35 Understanding Hormone Replacement Therapy 26:16 The Complexity of Hormonal Pathways 28:26 The Role of Stress in Hormonal Balance 30:22 Reprogramming the Nervous System 32:37 Nutrigenomics and Personalized Nutrition 36:27 The Power of Sulforaphane 39:04 Exploring Genetic Testing for Health Optimization To learn more about Annelie Smith:Email: annelie@3X4.io   Website: www.3X4Genetics.com   Reach out to us at:    Website: https://gladdenlongevity.com/     Facebook: https://www.facebook.com/Gladdenlongevity/    Instagram: https://www.instagram.com/gladdenlongevity/?hl=en     LinkedIn: https://www.linkedin.com/company/gladdenlongevity    YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw    

What if a single urine sample could screen for 50 diseases before you ever felt sick? Dejan Nenov, co-founder of AI diagnostics company Luventix, joins Dr. Joy Kong to explain how.Dejan Nenov has spent nearly a decade navigating FDA processes and clinical trials, and also founded Panaton, a healthcare IT company connecting hospitals, labs, and clinics across the US. Luventix uses machine learning to analyze 38,250 raw chemical data points in a single urine sample, identifying disease patterns without isolating a specific biomarker first. Its ongoing IRB-approved study covers roughly 1,250 patients across colorectal cancer, Crohn's, celiac disease, and SIBO. The same model can predict which patients will respond to a given treatment, a tool called companion diagnostics, and could eventually screen for dozens to hundreds of conditions from one low-cost sample. Dejan and Dr. Joy also cover the regulatory pathway for AI diagnostics, including the FDA's Lab Developed Test framework, and how genetics and metabolomics offer two different, complementary pictures of health.The conversation also covers a personal case: a close friend's daughter whose rare condition took years and specialists across ten states to diagnose, and why Dejan believes AI could have caught it sooner.Dr. Joy and Dejan close with what a fully AI-run hospital already looks like in China, and Dejan's vision for an at-home test, like a pregnancy test, that catches disease three to eighteen months before symptoms start.Dejan talks about:00:00 How a dog's nose inspired Luventix03:58 A dog's nose as a gas chromatograph04:22 Training AI to classify disease05:25 The 450-patient GI cancer trial06:54 Urine reflects the body's metabolic state08:07 Skipping biomarkers, reading raw data patterns11:00 38,250 data points per urine sample13:22 Metabolomics plus genetics, a fuller picture16:44 The single 50-disease urine panel18:51 FDA pathways: PMA vs. lab-developed tests22:20 Regulating AI models that keep improving36:11 Catching disease 18 months earlyAdditional Resources✨ Learn more about Luventix: https://www.luventix.com/ ✨ Read more about how AI offers an alternative to genetic testing: https://www.luventix.com/blog/ai-offers-alternatives-to-genetic-testing-to-make-disease-detection-more-accessible Visit My Clinic: Chara Health

Three cases sitting in front of three different systems. None of those systems have delivered what was promised.Nolan Wells was an eighteen-year-old who went to a boat party on Horn Island, Mississippi, and was the only one who did not come home. The state performed an autopsy and retained his throat. The trachea, hyoid bone, and laryngeal cartilage. Nineteen days later, no results released. The family's independent autopsy came back undetermined. A grand jury referral is pending.Nancy Guthrie has been missing from her Tucson home for close to six months with no arrest and no suspect named. On the same day in July, three FBI sources gave three contradictory answers about the ransom notes. A retired FBI agent told a national audience the case is cold. Genetic genealogy testing on DNA from her home started five months ago with no public update.Lindsay Clancy's jury is seated. Both sides agree she killed her three children. She was prescribed thirteen psychiatric medications in four months. After the children died, she was intubated in a hospital bed and wrote a single question on a whiteboard. The prosecution reads it as guilt. The defense reads it as confusion.A grand jury with subpoena power is pending in Mississippi. Three FBI sources in Arizona cannot agree on the nature of their own central evidence. A medical system in Massachusetts prescribed thirteen drugs, ignored a husband saying his wife had turned into a zombie, and the state now wants to prove that patient was sane beyond a reasonable doubt. None of these institutions delivered what they were built to deliver.Retired FBI Special Agent Jennifer Coffindaffer examines all three cases, the systems behind each, what connects their failures, and why none of them have produced the answers these families need.Join Our SubStack For AD-FREE ADVANCE EPISODES & EXTRAS!: https://hiddenkillers.substack.com/ Want to comment and watch this podcast as a video? Check out our YouTube Channel. https://www.youtube.com/channel/UC8-vxmbhTxxG10sO1izODJg?sub_confirmation=1 Instagram https://www.instagram.com/hiddenkillerspod/ Facebook https://www.facebook.com/hiddenkillerspod/ Tik-Tok https://www.tiktok.com/@hiddenkillerspod X Twitter https://x.com/TrueCrimePodThis publication contains commentary and opinion based on publicly available information. All individuals are presumed innocent until proven guilty in a court of law. Nothing published here should be taken as a statement of fact, health or legal advice.#NolanWells #NancyGuthrie #LindsayClancy #HiddenKillers #TrueCrime #JenniferCoffindaffer #FBI #GrandJury #InsanityDefense #PostpartumPsychosis

Father Nicanor Austriaco, a molecular biologist and Dominican Catholic priest, joins Trending with Timmerie: Episode Guide When should men be dating? (2:26) Uterine transplant – womb transplants to fix infertility? (19:15) Tuesday on Trending (38:42) Genetic engineering – "deextinction" of extinct species (39:45) Resources mentioned: Episode on the human experiment of surrogacy and IVF https://relevantradio.com/2026/07/st-mary-magdalene/ Transplanting the Womb: A Catholic Bioethical Analysis https://www.ncbcenter.org/store/transplanting-the-womb-a-catholic-bioethical-analysis

Three families asked the system for something basic. Answers. Protection. Help. None of them received it.Nolan Wells was eighteen. He went to a boat party on Horn Island, Mississippi, and was the only one of the group who did not come home. The state retained his throat during the first autopsy. Nineteen days later, no findings released. The independent autopsy returned undetermined. A grand jury is pending.Nancy Guthrie has been missing from Tucson for nearly six months. Three FBI sources gave three different answers about the ransom notes on the same day. A former FBI agent called the case cold on camera. Genetic genealogy testing began in February. Five months later, nothing.Lindsay Clancy's jury is seated in Plymouth Superior Court. Both sides agree she killed her three children. She was prescribed thirteen psychiatric medications in four months. Her husband told the doctors she had become a zombie. After the children died, intubated and unable to speak, she wrote a single question on a whiteboard. The prosecution and defense cannot agree on what that question means.A grand jury with subpoena power. An FBI that cannot agree on its own evidence. A medical system that prescribed thirteen drugs, ignored the husband's warnings, and now wants to prosecute the patient it failed. The institutions in each of these cases had one job and none of them did it.The grand jury can subpoena testimony under oath. The genetic genealogy lab has had DNA for five months and said nothing. The medical system that prescribed thirteen drugs and ignored the husband's warnings is now the same system the prosecution needs to prove produced a sane patient. Each institution had one responsibility and none of them fulfilled it.Retired FBI Special Agent Jennifer Coffindaffer examines all three cases, the thread connecting them, what the grand jury and the trial and the investigation should produce, and what the institutions handling each one owe to the families who are still waiting.Join Our SubStack For AD-FREE ADVANCE EPISODES & EXTRAS!: https://hiddenkillers.substack.com/ Want to comment and watch this podcast as a video? Check out our YouTube Channel. https://www.youtube.com/channel/UC8-vxmbhTxxG10sO1izODJg?sub_confirmation=1 Instagram https://www.instagram.com/hiddenkillerspod/ Facebook https://www.facebook.com/hiddenkillerspod/ Tik-Tok https://www.tiktok.com/@hiddenkillerspod X Twitter https://x.com/TrueCrimePodThis publication contains commentary and opinion based on publicly available information. All individuals are presumed innocent until proven guilty in a court of law. Nothing published here should be taken as a statement of fact, health or legal advice.#NolanWells #NancyGuthrie #LindsayClancy #HiddenKillers #TrueCrime #JenniferCoffindaffer #FBI #GrandJury #InsanityDefense #PostpartumPsychosis

In this episode Garth and special guest host Jane Halonen interview Nancy Segal from California State University, Fullerton in Fullerton, CA. Nancy discusses her lifelong twin research, books, and current projects. She describes how an undergraduate essay sparked her career, her work with the Minnesota twins reared-apart study, and how behavioral genetics became more accepted as evidence accumulated. She previews her trade book Twinship: What Twins' Ties Reveal About Relationships and notes she has nine published books, including work on Auschwitz twins, switched-at-birth Colombian identical twins, and a case involving gay fathers and twin sons. Nancy discusses twin-loss research, expert-witness cases, and doppelgangers used to counter "treated alike" critiques. She explains rising twinning rates (delayed childbirth, IVF), emphasizes twin studies' relevance to everyone, rejects evidence for "twin telepathy," and invites participation via her website and twin study center. [Note. Portions of the show notes were generated with Descript AI.]

“Is transhumanism a sin?” This question opens a discussion on the ethical implications of modern technology, including insights from the AI encyclical. The conversation also addresses whether IVF remains problematic, the Church’s stance on genetic engineering, and the complexities of recognizing AI as a unique life. Join the Catholic Answers Live Club Newsletter Invite our apologists to speak at your parish! Visit Catholicanswersspeakers.com Questions Covered: 05:30 – What is the main takeaway about transhumanism/ posthumanism from the AI encyclical. 16:00 – Is IVF still bad? 23:10 – Anthropology proves we come from apes. I don’t believe in Adam and Eve. How do you explain that? 34:28 – What does the Church say about genetic engineering and implants? 41:38 – At what level of advancement would the Church recognize AI as an individual unique life and baptize it? 45:28 – If a woman is able to undergo a procedure where she has her eggs frozen and later reimplanted without any damage to them or her, would this be ethical? 51:59 – Should we throw out the idea of humans coming from apes since we haven’t found any intermediate step between us and them?

Three different FBI sources. Three different answers. On the same day. About the single most important piece of evidence in the Nancy Guthrie kidnapping.Reuters said all the ransom notes are fabricated. The Phoenix field office said some may be legitimate. TMZ's sources said the original two are more credible than not. The Bureau cannot agree internally on whether the central evidence in its own active case is real or manufactured.Nancy Guthrie has been missing from her Tucson home for nearly six months. No suspect identified. No arrest. Former FBI agent Steve Moore went on camera and said what no official source has admitted. The case is completely cold. He told Brian Entin that fresh agents will eventually rotate in because the current investigators are stuck.This case has attracted cons alongside its genuine investigation. Derrick Callella pleaded guilty to posing as a kidnapper and sending fake ransom messages directly to Nancy's family while the real kidnapping was still open. Someone else separately sent TMZ a dozen emails demanding Bitcoin for information. The resources devoted to sorting real leads from manufactured noise have been enormous.Genetic genealogy testing began in February using DNA recovered from inside the house. That was five months ago. The enhanced photo of the masked figure on Nancy's porch has never been publicly released.Nancy's face is on the billboards across Tucson. The suspect's is not. The enhanced photo of the masked figure was captured on her porch camera. It has never been made public. These are deliberate decisions by the people running this investigation, and no one has explained the logic behind any of them.Retired FBI Special Agent Jennifer Coffindaffer joins Hidden Killers to examine the Bureau's contradictions, what happens mechanically when a case goes cold, whether the genetic genealogy testing has produced results that have not been shared, and whether investigators already know more about porch guy than they have told the public.Join Our SubStack For AD-FREE ADVANCE EPISODES & EXTRAS!: https://hiddenkillers.substack.com/ Want to comment and watch this podcast as a video? Check out our YouTube Channel. https://www.youtube.com/channel/UC8-vxmbhTxxG10sO1izODJg?sub_confirmation=1 Instagram https://www.instagram.com/hiddenkillerspod/ Facebook https://www.facebook.com/hiddenkillerspod/ Tik-Tok https://www.tiktok.com/@hiddenkillerspod X Twitter https://x.com/TrueCrimePodThis publication contains commentary and opinion based on publicly available information. All individuals are presumed innocent until proven guilty in a court of law. Nothing published here should be taken as a statement of fact, health or legal advice.#NancyGuthrie #FBI #HiddenKillers #TrueCrime #JenniferCoffindaffer #Tucson #PorchGuy #RansomNotes #PimaCounty #ColdCase

Watch every episode ad-free & uncensored on Patreon: https://patreon.com/dannyjones Ido Portal is the world's foremost expert on human movement. Ido has spent a lifetime studying, combining and evolving elements from an enormous range of martial arts, dance genres, athletic endeavors and science to develop a unified theory and practice of movement called “The Ido Portal Method.” https://www.idoportal.com SPONSORS https://whiterabbitenergy.com/?ref=DJP - Use code DJP for 20% off. EPISODE LINKS https://www.instagram.com/portal.ido https://www.idoportal.com FOLLOW DANNY JONES https://www.instagram.com/dannyjones https://twitter.com/jonesdanny OUTLINE 00:00 - The millionaire athlete approach to wellness 04:47 - Freshness & removing the mask of athletes 08:29 - Downside of "flow state" 17:43 - "World champions are robots" 22:06 - Become a practitioner 28:17 - You need to de-ambition yourself 30:41 - Why Ido makes Christian McCaffrey read & do math 38:36 - The spiritual journey of pro athletes 41:43 - Daily strength & conditioning practices 47:17 - Peripheral vision training 55:58 - Genetic ability vs. trained ability 01:04:22 - Doing what you suck at 01:13:27 - The state of mind of a practitioner 01:17:01 - Breathwork is oversimplified 01:25:57 - Movement design for Bollywood movies 01:28:34 - Indonesian "trance states" without drugs 01:35:44 - Psychological effects of desert training 01:38:02 - The Yoga lie 01:40:40 - Surfing vs. skateboarding vs. sports 01:45:59 - Why you shouldn't stretch 01:53:05 - The power of self-observation 02:01:34 - The active hanging challenge 02:06:31 - PEDs & the Enhanced Games 02:13:25 - Ido's view on supplements 02:16:31 - Suffering consciously 02:21:11 - Meditation has been distorted Learn more about your ad choices. Visit podcastchoices.com/adchoices

Dan Sullivan and Peter Diamandis discuss human enhancement, biotechnology, and entrepreneurship. Peter shares insights from the Enhanced Games in Las Vegas, where performance-enhanced athletes set just one world record, alongside ethical debates on embryo sequencing for IVF trait selection. They explore gene therapies, biohacking for muscle and cognitive gains, and AI’s power to enable solo founders, even those over 70, with leaner, lower-cost ventures. In this episode: Insights into the Enhanced Games where athletes used performance-enhancing drugs, and the ethical implications of genetic selection in IVF. Discover the latest advancements in gene therapies aimed at increasing muscle mass and cognitive abilities, and the societal pushback against these innovations. Explore the potential for a new educational system that fosters entrepreneurial spirit in students and the advancements in biotechnology aimed at extending human lifespan.

CardioNerds (Drs. Apoorva Gangavelli, Jenna Skowronski, and Hannah Every) discuss the continuum of prevention and heart failure with Drs. Anu Lala and Martha Gulati. Grounded in a clinical case of a 55-year-old woman with uncontrolled hypertension, type 2 diabetes, and obesity who is on the trajectory toward heart failure, this episode unpacks a paradigm-shifting framework from a joint HFSA/ASPC Scientific Statement. The discussion explores how prevention should not be siloed from heart failure management but rather integrated across a patient’s lifespan—from primary prevention in at-risk individuals, to secondary prevention in those with established heart failure, to tertiary prevention in patients with advanced therapies such as LVADs and heart transplantation. The experts highlight the importance of aggressive risk factor management, biomarker-guided screening, the AHA’s Life’s Essential 8, and the need for multidisciplinary collaboration and systems-level change to shift heart failure care from reactive to proactive. Audio editing for this episode was performed by CardioNerds Intern, Dr. Julia Marques Fernandes. Enjoy this Circulation 2022 Paths to Discovery article to learn about the CardioNerds story, mission, and values. US Cardiology Review is now the official journal of CardioNerds! Submit your manuscript here. CardioNerds Prevention PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls Systemic inflammatory diseases are associated with an elevated CVD risk that has significant implications for early detection, risk Heart failure prevention is a continuum, not a checkpoint. Prevention applies at every stage—from at-risk (Stage A) through advanced/post-transplant care—and every clinical encounter is an opportunity to intervene. The AHA’s Life’s Essential 8 (diet, physical activity, nicotine exposure, sleep, BMI, blood lipids, blood glucose, blood pressure) forms the foundation at every stage. Hypertension carries the highest population-attributable risk for heart failure of any modifiable risk factor. In the Framingham Heart Study, 91% of patients with newly diagnosed HF had pre-existing hypertension. The SPRINT trial demonstrated a 38% reduction in HF incidence with intensive blood pressure targets (30 ng/L or NT-proBNP >125 ng/L) identify individuals at heightened risk for progression to symptomatic HF. The ACC/AHA/HFSA guidelines give a Class IIa recommendation for natriuretic peptide screening in at-risk patients. Urine albumin-to-creatinine ratio (UACR) is an underutilized screening tool that provides additional insight into CKM risk. The heart failure label does not close the prevention window—it accentuates it. Secondary prevention through GDMT optimization (quadruple therapy in HFrEF) and continued risk factor management remains critical. Tertiary prevention extends to post-LVAD and post-transplant patients, where hypertension, diabetes, obesity, and CKD management remain essential to long-term outcomes. Show notes For a comprehensive review, please review the full HFSA/ASPC Joint Scientific Statement: Lala A, Beavers C, Blumer V, et al. The Continuum of Prevention and Heart Failure in Cardiovascular Medicine. J Card Fail. 2026;32:75-105. doi:10.1016/j.cardfail.2025.06.013 1. What is the “continuum of prevention” framework, and how does it differ from traditional approaches to heart failure prevention? Historically, prevention and heart failure management have been treated as separate disciplines—primary prevention handled by preventive cardiologists and treatment managed by heart failure specialists. This joint HFSA/ASPC Scientific Statement reframes prevention as a dynamic, continuous process that spans a patient’s entire lifespan, regardless of HF stage or ejection fraction. The framework maps onto the ACC/AHA HF staging system: Primary prevention targets Stage A (“at risk”) and Stage B (“pre-HF”) patients to reduce the burden of incident HF. Secondary prevention targets Stage C (symptomatic) and Stage D (advanced) patients to reduce the impact of established HF through GDMT optimization and ongoing risk factor management. Tertiary prevention encompasses risk factor management in patients with LVADs or heart transplants—populations where hypertension, diabetes, and obesity still drive outcomes. The Central Figure of the statement illustrates that Life’s Essential 8 (blood pressure and lipid control, diabetes management, exercise, sleep, smoking cessation, weight management, and diet/nutrition counseling) forms the foundation at every stage, with pharmacologic and device-based therapies layered on top as disease progresses (Figure) 2. How do traditional risk factors drive heart failure, and what should clinicians prioritize? Hypertension carries the greatest population-attributable risk for HF. In the Framingham Heart Study (N=5,143), HTN was associated with a 2- to 3-fold increased risk of HF, with a population-attributable risk of 39% in men and 59% in women. The SPRINT trial showed a 38% reduction in HF incidence and 25% reduction in the primary composite outcome with intensive BP targets (30 ng/L or NT-proBNP >125 ng/L) are associated with heightened risk for progression to symptomatic HF. In the ARIC study, incorporating NT-proBNP reclassified 20% of older adults without HF into Stage B. Factors that affect interpretation include age, sex, obesity (lower values), and CKD (higher values). High-sensitivity cardiac troponin (hs-cTn): Concentrations above the 99th percentile are now included in the definition of Stage B HF. Troponin testing may complement natriuretic peptides, particularly when BNP/NT-proBNP values are ambiguous. Risk scores: The PCP-HF equation predicts 10-year HF risk using traditional risk factors plus QRS duration. The AHA PREVENT score incorporates HF risk calculation and includes markers of kidney function (albuminuria, eGFR), though it may underestimate risk in men and Black adults. The CKM syndrome staging framework (Stages 0–4) provides a holistic approach to assessing systemic cardiovascular-kidney-metabolic risk. 4. What are the key nontraditional risk factors and cross-cutting themes in heart failure prevention? Genetics: Pathogenic cardiomyopathy variants exist in ~1 in 200 individuals in the general population. The HFSA and ACMG recommend cascade testing to identify at-risk family members. Polygenic risk scores for dilated cardiomyopathy show a 3.8-fold risk for DCM in the top 10th percentile compared with the median. Sex-specific considerations: Women have 2.8 times the odds of developing HFpEF, while men have similarly increased odds of HFrEF. A complete obstetric/gynecologic history is essential—preeclampsia is associated with a 4-fold increased risk of HF. Peripartum cardiomyopathy requires intentional screening in high-risk populations. Cardiotoxic exposures: Clinicians should be aware of medications that cause direct myocardial toxicity (e.g., anthracyclines, trastuzumab, tyrosine kinase inhibitors). A team-based approach with pharmacists can help optimize medication selection and risk factor modification. Social determinants of health: Environmental exposures (air pollution, arsenic, lead, cadmium), food insecurity, financial instability, and limited healthcare access contribute to HF risk and progression. Equity-focused, risk-based prevention strategies are needed. Psychological health: Depression is common in HF and independently associated with worse outcomes. Screening with brief questionnaires (e.g., PHQ-2) is recommended. Meditation, spirituality, and holistic wellness approaches remain underutilized. 5. What systems-level and policy changes are needed to move the needle on heart failure prevention? Multidisciplinary HF prevention clinics that bring together preventive cardiologists, HF specialists, endocrinologists, nephrologists, dietitians, pharmacists, exercise physiologists, and genetic counselors are advocated by the statement. EHR-embedded risk stratification could proactively flag patients on a trajectory toward HF—analogous to sepsis alerts or fall risk flags—enabling earlier intervention, particularly for patients who may not reach a cardiologist. Cardiac rehabilitation remains underutilized, particularly in HFrEF (Class 2b recommendation) and HFpEF (not yet covered by Medicare). The HF-ACTION trial showed quality-of-life benefits, and the REHAB-HF trial showed particular benefit in older patients with HFpEF. Policy priorities include expanding insurance coverage for preventive screening and novel therapies (SGLT2i, GLP-1 RAs, nsMRAs), reducing clinical inertia through team-based care models with closer follow-up intervals, and ensuring equitable access to evidence-based therapies across diverse populations. Digital health and AI hold promise for personalized risk prediction, remote monitoring (e.g., wearable devices, implantable PA pressure monitors), and virtual cardiac rehabilitation to overcome access barriers. Figure  Lala A, Beavers C, Blumer V, et al. The continuum of prevention and heart failure in cardiovascular medicine: a joint scientific statement from the Heart Failure Society of America and the American Society for Preventive Cardiology. J Card Fail. 2026;32(1):75-105. doi:10.1016/j.cardfail.2025.06.013) References Key references are bolded. Lala A, Beavers C, Blumer V, et al. The continuum of prevention and heart failure in cardiovascular medicine: a joint scientific statement from the Heart Failure Society of America and the American Society for Preventive Cardiology. J Card Fail. 2026;32(1):75-105. doi:10.1016/j.cardfail.2025.06.013 Heidenreich PA, Bozkurt B, Aguilar D, et al. 2022 AHA/ACC/HFSA guideline for the management of heart failure: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation. 2022;145(18):e895-e1032. doi:10.1161/CIR.0000000000001063 Lloyd-Jones DM, Allen NB, Anderson CAM, et al. Life’s Essential 8: updating and enhancing the American Heart Association’s construct of cardiovascular health: a presidential advisory from the American Heart Association. Circulation. 2022;146(5):e18-e43. doi:10.1161/CIR.0000000000001078 SPRINT Research Group, Wright JT Jr, Williamson JD, et al. A randomized trial of intensive versus standard blood-pressure control. N Engl J Med. 2015;373(22):2103-2116. doi:10.1056/NEJMoa1511939 Levy D, Larson MG, Vasan RS, Kannel WB, Ho KK. The progression from hypertension to congestive heart failure. JAMA. 1996;275(20):1557-1562. doi:10.1001/jama.1996.03530440037034 Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). JAMA. 2002;288(23):2981-2997. doi:10.1001/jama.288.23.2981 Yusuf S, Sleight P, Pogue J, et al. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. N Engl J Med. 2000;342(3):145-153. doi:10.1056/NEJM200001203420301 Zinman B, Wanner C, Lachin JM, et al. Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. N Engl J Med. 2015;373(22):2117-2128. doi:10.1056/NEJMoa1504720 Anker SD, Butler J, Filippatos G, et al. Empagliflozin in heart failure with a preserved ejection fraction. N Engl J Med. 2021;385(16):1451-1461. doi:10.1056/NEJMoa2107038 Solomon SD, McMurray JJV, Claggett B, et al. Dapagliflozin in heart failure with mildly reduced or preserved ejection fraction. N Engl J Med. 2022;387(12):1089-1098. doi:10.1056/NEJMoa2206286 Filippatos G, Anker SD, Agarwal R, et al. Finerenone reduces risk of incident heart failure in patients with chronic kidney disease and type 2 diabetes: analyses from the FIGARO-DKD trial. Circulation. 2022;145(6):437-447. doi:10.1161/CIRCULATIONAHA.121.057983 Solomon SD, McMurray JJV, Vaduganathan M, et al. Finerenone in heart failure with mildly reduced or preserved ejection fraction. N Engl J Med. 2024;391(16):1475-1485. doi:10.1056/NEJMoa2407107 Lincoff AM, Brown-Frandsen K, Colhoun HM, et al. Semaglutide and cardiovascular outcomes in obesity without diabetes. N Engl J Med. 2023;389(24):2221-2232. doi:10.1056/NEJMoa2307563 Deanfield J, Verma S, Scirica BM, et al. Semaglutide and cardiovascular outcomes in patients with obesity and prevalent heart failure: a prespecified analysis of the SELECT trial. Lancet. 2024;404(10454):773-786. doi:10.1016/S0140-6736(24)01498-3  Kosiborod MN, Abildstrøm SZ, Borlaug BA, et al. Semaglutide in patients with heart failure with preserved ejection fraction and obesity. N Engl J Med. 2023;389(12):1069-1084. doi:10.1056/NEJMoa2306963 Ndumele CE, Neeland IJ, Tuttle KR, et al. A synopsis of the evidence for the science and clinical management of cardiovascular-kidney-metabolic (CKM) syndrome: a scientific statement from the American Heart Association. Circulation. 2023;148(20):1636-1664. doi:10.1161/CIR.0000000000001175 Khan SS, Matsushita K, Sang Y, et al. Development and validation of the American Heart Association’s PREVENT equations. Circulation. 2024;149(6):430-449. doi:10.1161/CIRCULATIONAHA.123.067626 Khan SS, Ning H, Shah SJ, et al. 10-year risk equations for incident heart failure in the general population. J Am Coll Cardiol. 2019;73(19):2388-2397. doi:10.1016/j.jacc.2019.02.057 Bozkurt B, Fonarow GC, Goldberg LR, et al. 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Well guys, it's been a heck of a week - apologies for getting this out somewhat late, my brain is *egg of frying pan sound.* I know you all can understand. Be prepared! I learn some neuroscience and immunology today because it's a ~fully body~ Schauer this week, ayo! I'd like to thank my parents for bestowing me with a last name rife with self-branding related puns. I appreciate you all! Chat next week! Books: A Silent Fire: The Story of Inflammation, Diet & Disease - Shilpa Ravella (Transplant Gastroenterologist) Most Delicious Poison: The Story of Nature's Toxins - from Spices to Vices - Noah Whiteman (Evolutionary Biologist) The Human Brain Book: A Visual Guide to Structure & Function - Rita Carter (Science & Medicine Writer) Behave: The Biology of Humans at Our Best and Worst - Robert M. Sapolsky (Neuroscientist & Primatologist) Why We Sleep: Unlocking the Power of Sleep and Dreams - Matthew Walker, PhD (Prof. of Neuroscience & Psychology) An Elegant Defense: The Extraordinary New Science of the Immune System - Matt Richtel (Pulitzer Prize Winning Writer for NYT) Organ Speak: What It Really Means to Listen to Our Bodies - Guilia Enders (Physician, Microbiologist, Author) The Mind-Gut Connection: How the Hidden Conversations Within Our Bodies Impact Our Mood, Our Choices, and Our Overall Health - Emeran Mayer, MD (Gastroenterologist & Educator)  Clean: The New Science of Skin and the Beauty of Doing Less - James Hamblin, MD, MPH (Preventative Medicine Specialist) Believe it or not, I got most of my soap information from this book (I also used the ‘Natural saponins' link below) - it's mainly about hygiene and the cosmetic industry ripping everyone off but it did also teach me how to make soap.  Also, most of the sources from this episode are from the books I've read over the years, if there's information you can't find linked below, it has come from a book listed above. I put everyone's occupations to narrow down what book it's likely from.  Online Sources: Good News - Attorney General James Sues Some of Nation's Largest Chemical Companies Over Toxic Pollution from Consumer Products https://ag.ny.gov/press-release/2026/attorney-general-james-sues-some-nations-largest-chemical-companies-over-toxic Researchers discover the eye's hidden cleanup system https://medicalxpress.com/news/2026-07-eye-hidden-cleanup.html Macrophages in the artery wall ‘smell' their surroundings https://www.lji.org/news-events/news/post/macrophages-in-the-artery-wall-smell-their-surroundings/ Cells That ‘Taste' Danger Set Off Immune Responses https://www.quantamagazine.org/tuft-cells-that-taste-danger-set-off-immune-responses-20191115/ Natural saponins and macrophage polarization: Mechanistic insights and therapeutic perspectives in disease management https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2025.1584035/full Inflammation Forces Brain Stem Cells to Halt Neurogenesis https://neurosciencenews.com/inflammation-neurogenesis-31011/ Inhaling high-dose CO2 clears Alzheimer's proteins from the brain https://www.newscientist.com/article/2580471-inhaling-high-dose-co2-clears-alzheimers-proteins-from-the-brain/ Genetic variation across the human olfactory receptor repertoire alters odor perception https://www.pnas.org/doi/10.1073/pnas.1804106115  Comparative Toxicogenomics Database https://ctdbase.org/ This is just the think to the genetics database I've been using, for all the genes I mention just type them into the search and *voila*  Free Newspaper Archive: UCR | California Digital Newspaper Collection  https://cdnc.ucr.edu/ Learn more about your ad choices. Visit podcastchoices.com/adchoices

Animals have a genetic switch that puts them in winter mode Study reveals a winter version of the biological clock Contact the Show: coolstuffdailypodcast@gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Elizabeth Bruenig, staff writer at The Atlantic, discusses how the new data available on inherited maladies can save lives but can also complicate the decision people make about treatment. Photo: Female doctor sharing electronic test results with patient at clinic. Medical expert and woman are examining reports. They are sitting in examination room. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

The "man-moulders of the new age" vs. Imago Dei. __________ Partner with thousands of others in supporting The Colson Center by visiting colsoncenter.org/cornerstone.

All Home Care Matters and our host, Lance A. Slatton were honored to welcome Josh Bowie and Dr. Divyen Patel from Your Genetic Wellness as guests to the show.   About Naga V. Naidu, Ph.D., Lab Director at Your Genetic Wellness:   Dr. Naga V. Naidu is a PhD-trained toxicologist and laboratory leader with more than 10 years of experience in forensic and clinical diagnostic laboratories. He earned his PhD in Toxicology in Houston, Texas, following completion of his bachelor's degree in pharmacy in India. Early in his career, he served as Scientific Laboratory Director at a forensic toxicology laboratory and achieved board certification as a Toxicology Chemist through the National Registry of Certified Chemists (NRCC).   Dr. Naidu has held multiple leadership and technical roles across forensic and clinical diagnostic environments. He currently serves as a General and Technical Consultant Director for several Clinical Diagnostic Laboratories, where he provides oversight in laboratory operations, test development, validation, regulatory compliance, and quality systems management.   His expertise includes method development and validation of advanced analytical platforms used in toxicology, molecular diagnostics, and genetic testing. Dr. Naidu has experience reviewing and supporting genotype-based testing panels and translating molecular data into clinically meaningful wellness and risk-assessment frameworks.   In addition to his technical expertise, Dr. Naidu is highly experienced in laboratory compliance and regulatory standards, including CLIA, CAP, proficiency testing, and quality assurance systems. His multidisciplinary background allows him to bridge scientific rigor, clinical relevance, and regulatory integrity, ensuring high-quality, reliable genetic and diagnostic testing.   About Josh Bowie, SVP of Strategy & Insights at Your Genetic Wellness:   Josh Bowie is a creative strategist and systems thinker dedicated to solving the "Last Mile" problem in precision health. As the SVP of Strategy & Insights at Your Genetic Wellness, Josh serves as the Strategic Lead for the Results to Routines™ framework, a methodology designed to translate complex biological data into clear, actionable wellness pathways for everyday life.   Josh's approach is rooted in the belief that data is only as valuable as the habits it inspires. He moves beyond the traditional model of overwhelming, static health reports, focusing instead on Actionable Biology: a human-centric design where technology and clinical expertise intersect to create sustainable change. By synthesizing market signals with a unique perspective on consumer behavior, Josh ensures that Your Genetic Wellness functions as a "GPS for the Human Body," empowering individuals to navigate their health with confidence and clarity.   A vocal advocate for collaborative wellness, Josh emphasizes that the most successful health journeys are never walked alone. His work focuses on building the bridges between cutting-edge science and the real-world decisions that define long-term vitality, ensuring the future of health is both personalized and profoundly practical.   About Your Genetic Wellness:   Your Genetic Wellness is shifting the conversation from reactive care to proactive clarity. Too often, we wait until symptoms appear before investigating our health, forcing us into a cycle of trial and error to find relief.   We believe in a different approach: providing a personal biological roadmap before the guesswork begins. Using a simple at-home swab, we translate unique genetic markers into clear, actionable insights that show how a body may process nutrients, respond to medications, and manage long-term wellness.   Whether you are a proactive professional, a parent, or a caregiver, we provide the data-driven confidence to move away from reactive "sick care" and toward more informed, personalized health decisions.

A rare drug reaction unraveled your mind — twice. Your grown kids know nothing of what runs in their blood. Tell them, or wait? Welcome to Feedback Friday!And in case you didn't already know it, Jordan Harbinger (@JordanHarbinger) and Gabriel Mizrahi (@GabeMizrahi) banter and take your comments and questions for Feedback Friday right here every week! If you want us to answer your question, register your feedback, or tell your story on one of our upcoming weekly Feedback Friday episodes, drop us a line at friday@jordanharbinger.com. Now let's dive in!Full show notes and resources can be found here: jordanharbinger.com/1355On This Week's Feedback Friday:If you want to take a quick plane ride across the sea of Jordan's reflections on China during his month-long trip there, you can jump to about 30 minutes, five seconds. Sheh-sheh, and enjoy!You've wrestled inflammatory conditions your whole life, until a teenage steroid reaction detonated into psychosis. Years later, a manic episode nearly made you the accidental CEO of Best Buy. Now your kids are young adults, and you're sitting on a medical history you've never breathed a word of. Do you tell them, or wait for fate to force your hand?10-plus years married, two kids, a well-oiled co-parenting machine, but behind closed doors, the romance flatlined years ago. Then a woman at a Vegas conference lit up something long dormant, and the texts have drifted from casual to dangerously deep. Is "emotional cheating" even real — and is this connection, or just a mirage?Recommendation of the Week: Use this prompt (courtesy of listener Ben) with your AI of choice to prepare for layoffs and/or a job search.You fired off a newsletter with the subject line "Saw your name in the Epstein files" — a wink, a test, a point about curiosity owing its audience real substance. Most readers howled with laughter. A furious few grabbed pitchforks. What does the split reaction — and the open-rate data — quietly reveal about how we choose to engage?Have any questions, comments, or stories you'd like to share with us? Drop us a line at friday@jordanharbinger.com!Connect with Jordan on Twitter at @JordanHarbinger and Instagram at @jordanharbinger.Connect with Gabriel on Twitter at @GabeMizrahi and Instagram @gabrielmizrahi.And if you're still game to support us, please leave a review here — even one sentence helps! Sign up for Six-Minute Networking — our free networking and relationship development mini course — at jordanharbinger.com/course!Subscribe to our once-a-week Wee Bit Wiser newsletter today and start filling your Wednesdays with wisdom!Do you even Reddit, bro? Join us at r/JordanHarbinger!This Episode Is Brought To You By Our Fine Sponsors: BetterHelp: 10% off first month: betterhelp.com/jordanDripDrop: 20% off: DripDrop.com, code JORDANNorthwest Registered Agent: Get more at northwestregisteredagent.com/jordanAG1: Welcome kit: drinkag1.com/jordanSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.