Podcasts about Progression

The ASAP Career Stages Framework is a data-driven resource for executive assistants and administrative professionals to identify skills gaps and map their career progression. Want something executives and HR will listen to and that will move the needle for your career advancement? This is it. Recorded at EA Ignite Spring 2025 and produced by the American Society of Administrative Professionals - ASAP. Learn more and submit a listener question at asaporg.com/podcast.

In this episode of the Four-Eyed Professor podcast, Dr. Chris Lievens and Dr. Jessica Steen discussed how to recognize GA, how to monitor its progression, and how to guide patients through treatment discussions. Optometrists are increasingly asked not only what IZERVAY is and what it is used for, but also practical questions about how an IZERVAY eye injection works and what patients should expect.

In this Talk Dizzy to Me episode, vestibular physical therapists Dr. Abbie Ross, PT, NCS and Dr. Dani Tolman, PT sit down with Dr. Mike Studer, DPT, MHS, NCS, CEEAA, CWT, CSST, CSRP, CBFP, FAPTA to unpack neuroplasticity—what it is, how it works, and how to apply it in vestibular rehabilitation. We cover dual tasking, prediction error, fear-avoidant vs. fear-adapted movement, motivational interviewing, and patient-directed dosage using the OPTIMAL theory of motor learning. Mike shares practical clinic and real-life examples (driving, grocery stores, cooking), mic-drop lines you'll quote to patients, and how to talk to insurers using objective measures.If busy visuals or movement bother you, consider listening on Apple Podcasts/Spotify.Neuroplasticity = learning. It's not just more pathways; it's stronger, faster, better-fed pathways that consolidate during sleep.Dose the meaningful. Intensity, repetitions, salience, and task specificity drive consolidation (“put a post-it on that memory”).Exposure works. Habituation/adaptation creates prediction error (“that wasn't as bad as I expected”), reinforcing change via dopamine.Fear shows up in movement. Beyond fear-avoidant behavior, watch for fear-adapted movement (reduced head turns, co-contraction, slow/over-intentional strategies).Dual tasking is two goals, not ‘think-and-move' toward one goal. Use cognitive+motor or visual+motor loads that are personally salient.Autonomy accelerates progress. Let patients choose dosage (keep, dial down, or push), using motivational interviewing and OPTIMAL theory.No expiration date. Neuroplastic change remains possible well beyond 1 year—set expectations and use objective measures to justify care.Connect with MikeEmail: mike@mikestuder.comWebsite: mikestuder.comInstagram: @MikeStuderDPTBook: The Brain That Chooses ItselfTime Stamps03:29 Neuroplasticity defined 05:21 Core principles: intensity, repetitions, salience, task specificity, sleep consolidation09:35 Zooming into vestibular rehab10:06 VR as proof of neuroplasticity; predictive processing 11:32 Habituation/adaptation as exposure-based therapy; links to pain & psychology13:32 Fear, expectations, and patient education14:28 Therapeutic alliance: precision starts with the person17:42 Treating fear: exposure-response prevention & prediction error (dopamine wins)20:05 Dosage variables + motivational interviewing + OPTIMAL theory21:27 Threat perception, amygdala, and “roadblocking” fear pathways24:13 Fear-avoidant vs. fear-adapted movement (new concept in progress)26:11 Cognitive load, exhaustion, and dual-task intolerance29:32 Building alliance between sessions (check-ins)30:00 What dual tasking is (and isn't): two separate goals31:32 Clinic examples: cognitive+motor; visual+motor with busy backgrounds34:51 Real life: driving with kids, grocery stores, cooking; task switching vs. dual tasking38:40 Overtraining in clinic to empower life outside39:10 Progression: patient-controlled dosage (autonomy)43:27 Neuroplasticity at any age; caveats for degenerative conditions45:26 “Road crew at night” metaphor; why sleep matters47:13 The “1-year” myth; talking to insurers with objective measures49:27 Mic-drop linesHosted by:

This week I'm joined once again by Dutch ATP player Jesper de Jong, who has continued his steady rise on the professional circuit.Since our last chat, Jesper has broken into the top 100, reached his first ATP final at the Swedish Open, and played a key role for the Netherlands in Davis Cup. We talk about what feels different now that he's inside the top 100, the lessons he's learned from the tour grind, and how he balances results with enjoying the process. Jesper also shares insights from training blocks in Bali, the unforgettable match that sealed his top 100 spot, and what he's learned from his girlfriend, a professional speed skater.If you're curious about the mindset and habits behind steady, sustainable progress, this episode is a great listen.FabioThis podcast is sponsored by ASICS. ASICS is a Japanese company founded in 1949 to give more people the opportunity to experience how sports and movement can have a positive impact on mental well-being.To learn more about ASICS visit their website here: https://www.asics.com/nl/en-nl/sports/tennis/Find us on Social Media:Instagram: Instagram.com/FunctionalTennisTikTok: https://www.tiktok.com/@functionaltennis

Hit the Net, Climb Back Up: Embracing Life's Valleys as SpringboardsWhat if your biggest challenges were actually divine preparation for your greatest purpose? Join us as Robin Edgar, seasoned wealth strategist with 35+ years of experience, shares her remarkable journey from teenage motherhood to guiding clients through life-changing financial decisions.Robin introduces her powerful "trapeze analogy" that reframes how we view life's transitions. "We can be swinging comfortably on our trapeze, but real growth happens when we let go to catch the next bar," she explains with hard-earned wisdom. "The space between—catching air—that's where transformation happens." Her framework of living at the intersection of faith, family, and finance offers a refreshing holistic approach to decision-making that transcends typical financial advice.This conversation goes far beyond money matters. Robin reveals practical strategies for navigating major life decisions, including her two-step approach: creating a detailed pro/con list and asking "what's the worst that could happen?" She challenges listeners to examine who they're seeking advice from, noting that "don't take advice from people more messed up than you" and "if you're the smartest person in the room, you're in the wrong room."Perhaps most powerful is Robin's perspective on life's valleys. "Your muscles aren't built by swinging back and forth on the trapeze. They're built when you hit the net," she shares, explaining how her own challenging moments became the foundation of her strength. Her mantra to "begin with the end in mind" provides a clarifying lens for evaluating choices, whether in business, parenting, or personal growth.Ready to rethink how you approach transitions and build strategy around the people you surround yourself with? Listen now and discover how to transform setbacks into springboards toward your greater purpose.Resources Mentioned:Book: 7 Habits of Highly Effective People by Stephen R. CoveyConnect with Robin:Personal Website: Robin EdgarBusiness Website: Wealth Progression GroupEmail: Contact the Host, Kelly Kirk: Email: info.ryh7@gmail.com Get Connected/Follow: The Hue Drop Newsletter: Subscribe Here IG: @ryh_pod & @thekelly.tanke.kirk Facebook: Reclaiming Your Hue Facebook Page Credits: Editor: Joseph Kirk Music: Kristofer Tanke Thanks for listening & cheers to Reclaiming Your Hue!

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APPRENDRE À APPRENDRE ? Dans cet épisode captivant de Princesse Montessori, Xénia Troubetzkoï nous plonge dans l'univers fascinant de l'APPRENTISSAGE et de la STRUCTURATION de l'éducation. Elle nous rappelle que sans une MÉTHODE claire, chaque minute d'apprentissage peut devenir une source de FRUSTRATION et de FATIGUE. Comment éviter cela ? Xénia propose une approche basée sur des OBJECTIFS CLairs et OBSERVABLES, couplée à des ACTIONS IMMÉDIATES qui renforcent la MÉMOIRE et l'ATTENTION de vos enfants. Elle partage avec nous trois LEVIERS puissants pour faciliter l'apprentissage :Lecture Quotidienne : Instaurer un moment quotidien pour plonger dans les livres, c'est ouvrir la porte à un monde de connaissances. Automatisation de la Mémoire : Utiliser des cartes pour rendre l'apprentissage ludique et efficace. Entraînement à la Photomémoire : Des techniques qui permettent aux enfants de retenir facilement l'information. Xénia souligne également l'importance d'un ENVIRONNEMENT CALME et d'un ADULTE COMPÉTENT pour guider les enfants dans leur apprentissage. Elle offre des conseils pratiques adaptés à chaque âge, incitant les parents à établir des RITUELS d'apprentissage courts mais réguliers. Ces rituels ne sont pas seulement bénéfiques, ils sont ESSENTIELS pour créer une HABITUDE d'apprentissage durable. En fin d'épisode, Xénia lance un défi aux parents : mettre en place un RITUEL d'apprentissage de 10 minutes par jour. Elle insiste sur le fait que la PROGRESSION visible sera une SOURCE de MOTIVATION inestimable pour vos enfants. N'attendez plus pour découvrir comment ces simples changements peuvent faire une DIFFÉRENCE significative dans l'éducation de vos enfants. Rejoignez-nous pour cette discussion enrichissante et apprenez comment faire de l'apprentissage une AVENTURE passionnante et efficace pour vos enfants avec Princesse Montessori !

Mark 4:1-20 1 Again Jesus began to teach by the lake. The crowd that gathered around him was so large that he got into a boat and sat in it out on the lake, while all the people were along the shore at the water's edge. 2 He taught them many things by parables, and in his teaching said: 3 "Listen! A farmer went out to sow his seed. 4 As he was scattering the seed, some fell along the path, and the birds came and ate it up. 5 Some fell on rocky places, where it did not have much soil. It sprang up quickly, because the soil was shallow. 6 But when the sun came up, the plants were scorched, and they withered because they had no root. 7 Other seed fell among thorns, which grew up and choked the plants, so that they did not bear grain. 8 Still other seed fell on good soil. It came up, grew and produced a crop, multiplying thirty, sixty, or even a hundred times." 9 Then Jesus said, "He who has ears to hear, let him hear." 10 When he was alone, the Twelve and the others around him asked him about the parables. 11 He told them, "The secret of the kingdom of God has been given to you. But to those on the outside everything is said in parables 12 so that, " 'they may be ever seeing but never perceiving, and ever hearing but never understanding; otherwise they might turn and be forgiven!' " 13 Then Jesus said to them, "Don't you understand this parable? How then will you understand any parable? 14 The farmer sows the word. 15 Some people are like seed along the path, where the word is sown. As soon as they hear it, Satan comes and takes away the word that was sown in them. 16 Others, like seed sown on rocky places, hear the word and at once receive it with joy. 17 But since they have no root, they last only a short time. When trouble or persecution comes because of the word, they quickly fall away. 18 Still others, like seed sown among thorns, hear the word; 19 but the worries of this life, the deceitfulness of wealth and the desires for other things come in and choke the word, making it unfruitful. 20 Others, like seed sown on good soil, hear the word, accept it, and produce a crop--thirty, sixty or even a hundred times what was sown." NIV 84 Lesson Notes The Kingdom Looks Different Than Expected: Instead of arriving with royal pageantry or military power, Jesus compares the kingdom of God to a farmer sowing seed—small, quiet, and grassroots, yet destined for great harvest. Parables Are More Than Illustrations: Warren Wiersbe described parables as starting as a picture, becoming a mirror where we see ourselves, and then a window through which we see God and His truth. The Progression of the Soil: Jesus' parable shows a progression of the heart—from hard soil, to shallow, to crowded with weeds, to fruitful soil producing thirty, sixty, or even a hundredfold. Everyone is somewhere along this journey, and there is always room for growth. The Weeds of the Heart: Worry, wealth, and worldly desires remain timeless distractions that choke out spiritual growth if not pulled up by the root. They may not always be “bad things,” but they become harmful when they take priority over God. The Generous Sower: The parable ultimately reveals God as the Sower, who lavishly scatters His Word on all types of soil. His invitation is for everyone to receive the kingdom—promptly, deeply, totally, and abundantly. DISCUSSION QUESTIONS 1. When you hear the phrase “kingdom of God,” what images or expectations come to mind, and how does Jesus' description in Mark 4 reshape your understanding? 2. Looking at the “soil progression” Jesus describes, where would you honestly place yourself right now—and what would it look like for you to take the next step toward deeper fruitfulness? 3. Of the three weeds—worry, wealth, or worldly distractions—which one most often threatens to choke out your spiritual growth? What practical steps could help you “pull it up by the roots”? 4. Parables act as a picture, a mirror, and a window. Which of these three aspects of the parable of the sower (picture of the kingdom, mirror of the heart, or window into God) spoke to you most in this sermon, and why?

We've all been playing Hades II and discussing our early thoughts on the game, a sequel to one of our collective favourites. Show Dot Points Hades 2 introduces new gameplay mechanics that enhance strategy. The art style and music continue to impress players. Progression feels rewarding, regardless of the success of the run. The game features a complex system of collectibles and upgrades. Character relationships are more intricate in Hades 2. The stakes in the story are higher compared to the first game. Players appreciate the depth of Greek mythology in the narrative. The game maintains a balance between challenge and accessibility. Feedback on the game's systems varies among players. The community is excited for future updates and expansions. The hex system in Hades adds a unique layer to gameplay. State of Play revealed exciting new titles and updates. Zero Parades is anticipated to capture the essence of Disco Elysium. Microsoft Flight Simulator 2024 is coming to PlayStation, a surprise to many. Battlefield 6's cinematic trailer draws comparisons to Call of Duty. The gaming community is eager for more depth in Wolverine's gameplay. PlayStation Plus is offering a strong lineup for October. Gran Turismo continues to thrive with its loyal fanbase. The evolution of game mechanics is crucial for player engagement. The hosts express mixed feelings about new hardware announcements. The game design of upcoming titles may lean towards linear storytelling rather than open-world exploration. Character relationships in the X-Men universe hold significant potential for deeper storytelling. Sony's new reward system for PlayStation has received mixed reactions from the gaming community. Forza Horizon 6 promises to bring a fresh setting and exciting gameplay mechanics. Yakuza Kiwami 3 will not only remake the original but also expand on its story with new content. Nintendo's leadership change marks a significant moment in the company's history, especially with the appointment of a female president. The new RPG Anata showcases a blend of popular gaming mechanics from various franchises. The gaming community is eager for more X-Men characters in upcoming titles. The reaction to PlayStation's merchandise gatekeeping reflects broader trends in gaming culture. The anticipation for Forza Horizon 6 highlights the franchise's evolution and commitment to diverse settings. Hosts: Dylan Blight: https://twitter.com/vivaladil Ashley Hobley: https://twitter.com/ashleyhobley Ciaran Marchant: https://twitter.com/YaboyRingo Resources State of Play September 2025: Wolverine, Saros, and Every Trailer Revealed - Explosion Network Earn Trophies, Get Gear: PlayStation's New Rewards Program Starts With Ghost of Tsushima - Explosion Network Forza Horizon 6: Answering the Big Questions About That Japan Setting - Xbox Wire Yakuza Kiwami 3 Announced for February 2026 With New Spin-Off Dark Ties - Explosion Network Bowser retires from Nintendo, succeeded by first female president | Eurogamer.net Arcade Couch Credits: Music by: Dylan Blight Art by: Cherie Henriques Summary Show Notes: Created by Riverside.FM AI Integration All Episodes: https://explosionnetwork.com/arcade-couch/ Support Us: https://explosionnetwork.com/support

The Celtics, Kings, Heat, Grizzlies, and Pacers aren't title contenders, but they're not tanking either. Stuck in no man's land, should these teams chase lottery luck or bet on internal growth? Sam Sheehan of YKB joins the show for a mix of real analysis and some well earned Kings bashing. A fun one with one of the best in the game. Like, rate, subscribe, and share! Check out The Drop Step here: https://x.com/TheDropStepNBA Check out YKB on YT here: https://www.youtube.com/@youknowball Check out Sam here: https://x.com/NBABabySecret Learn more about your ad choices. Visit megaphone.fm/adchoices

For many, last year made it impossible to ignore the scale of global change — what we see as global instability is only one dimension of a larger meta-crisis. Portals has been following the signs of this broader evolutionary cycle, which is reshaping our planet and humanity. With the epoch insight and perspective, we can trace the emergence and patterns of this epochal movement across every area of life, from grand global systems to everyday human endeavors.In the latest conversation from the The Universalis Project, Aviv Shahar is joined by Karen Heney and Kyriaki Nikandrou to explore the flow of history and evolution through a “7-fold epoch.” This special lens examines the nature of each epochal impulse and its influence on culture, as well as on human growth and development. The epoch framework is not a new meta-theory about life or evolution; instead, it reflects an observable quality within all natural processes. We can see 7-fold patterns in the natural world — including flora, fauna, and human behavior.For instance, the world's major religions arose during the Yellow phase of planetary evolution, while the drive to resolve conflict, balance pressures, and collaborate in scalable systems reflects a Blue impulse.Other insights from this exploration include:The nature of Red: This planet, in its cosmology in the galaxy, and its function as the cradle for evolving conscious life, discovers the unique emergence of a new epoch and conscious life in the frequency and nature of Red.Indigo theater: Social media and the internet represent a fantastic Indigo theater of merging and transference.Violet phase-shift: In the larger purpose of the epoch, a great endeavor or civilization ends in Violet as part of a phase-change to the next evolutionary leap, sometimes with a violent dimension.Living History: The living experience of history — the energy — has not been destroyed; those memories, feelings, and sentiments are encapsulated in time; as we become attuned, we feel the living nature of their experience.Capacity for destruction: The unfolding story of the evolution of life includes the capacity to destroy it. We help metabolize lower influences by expanding consciousness and unlocking higher human capabilities.• Indigo-Violet Acceleration: A core premise of the epoch study is that it's a continuing revelation inside the context of a rolling event — the Indigo-Violet acceleration, as witnessed through the meta-crisis and other profound planetary change.This conversation is part of the continuing Portals discovery into what is emerging on the frontiers of human experience in this time of profound change. Information about upcoming special events can be found on the Events page. Also visit and subscribe to our YouTube channel. TWEETABLE QUOTES “So the story of the evolution of life is accompanied by the story of the development of the capacity to destroy life. And the reason we feel so compelled to bring the consciousness of this story into being is that there is an awareness that when we bring consciousness to this story, we may intensify and unlock capacities for humanity to do both the healing and liberation work, at all the levels, the level of the individual, the level of the group, and the level of the tribe and the nation.” (Aviv)“Every human that's born on the planet, it's designed in such a way that every life can have a spiritual journey, can have a connective, purposeful life. And we're all born into this unfolding epoch. First of all, we need to be aware of it, which is the wonder of these recordings and this journey. Because if we become aware of it, and we opt in to being consciously mindful of these different progressions, then we're saying that we can co-join evolution and a human update.” (Karen) RESOURCES MENTIONED Portals of Perception WebsiteAviv's LinkedIn Aviv's TwitterAviv's WebsiteThe Universalis Project #13: The 7-fold Epoch Progression

In this episode, Sara Tolaney, MD, of Dana-Farber Cancer Institute, discusses sequencing strategies after progression in HER2-positive metastatic breast cancer. She reviews current second-line standards, considerations for patients with brain metastases, and emerging therapies in the post–T-DXd setting.Let us know what you thought of this week's episode on Twitter: @physicianswkly Want to share your medical expertise, research, or unique experience in medicine on the PW podcast? Email us at editorial@physweekly.com! Thanks for listening!

In this engaging conversation, Zach Davis and Steve Parker delve into the intricacies of blocking techniques in youth football. They explore the progression from basic to elite blocking strategies, innovative terms like 'jaw' blocking, and the effectiveness of wedge blocking. The discussion also covers pass protection strategies and addresses common issues faced in youth football, particularly concerning A-gap protection. Throughout the conversation, the hosts share personal anecdotes and insights, making it a valuable resource for coaches and players alike. Chapters 00:00 Introduction and Overview of Blocking Part Two 02:56 Progression of Blocking Techniques for Youth Football 05:56 Basic to Elite Blocking Strategies 08:39 Innovative Blocking Terms and Techniques 11:52 Wedge Blocking and Its Effectiveness 14:45 Pass Protection Strategies 17:47 Addressing A-Gap Issues in Youth Football 20:30 Final Thoughts on Blocking Techniques Learn more about your ad choices. Visit megaphone.fm/adchoices

David welcomes Andy McGowan to look back over the much-needed win over Hibs in the Premier Sports Cup. EXCLUSIVE NordVPN Deal ➼ https://nordvpn.com/heartandhand Try it risk-free now with a 30-day money-back guarantee - Watching Sporting Events/TV Shows/Films which aren't available in your region by switching your virtual location to a country which is showing the event. E.g. if you are abroad then you can access all your streaming services from back home. - Protect your private data like bank details, passwords and online identity - NordVPN can switch your virtual location allowing you to save money by purchasing flights, hotels, subscriptions from other countries at a cheaper price - Protecting your data whilst traveling and using public wifi, NordVPN protects you wherever you are in the world - NordVPN Threat Protection feature protects you from viruses, malicious malware and phishing sites - Fastest VPN in the world - no buffering/lagging whilst streaming and stops your ISP bandwidth throttling - Premium cyber-security for the price of a cup of coffee per month - 1 NordVPN account can be used on up to 10 devices Learn more about your ad choices. Visit podcastchoices.com/adchoices

Kristen KellyExecutive Director & Co-founderPeople of ProgressionCall or Text: (920) 288-2292Email: kristengondek@peopleofprogression.orghttps://www.peopleofprogression.com/

by Brooks Simpson | From the Series: Walking with Jesus | Scripture: Matthew 5:3-6 | Download Audio

by Brooks Simpson | From the Series: Walking with Jesus | Scripture: Matthew 5:3-6 | Download Audio

rwh20sept Ep.382 – Run With Horses Podcast –   Podcast: rwh.podbean.com Website: www.runwithhorses.net Youtube:  https://youtube.com/@rwhpodcast Facebook:  https://www.facebook.com/RWHpodcast Instagram: https://www.instagram.com/rwh_podcast Twitter:  https://twitter.com/RWH_podcast Author pages with links to all books on Amazon. https://www.amazon.com/stores/author/B0BCSDDVLB – James Norman Smith https://www.amazon.com/stores/author/B0BMGW51FW – Susan Jane Smith **(24:00)** The questions you ask often determine the kinds of answers you get. How do our questions impact our ability to make disciples, develop leaders and plant new churches? That's the topic of today's show! Welcome to Run With Horses! My name is Norman and my goal is to help you thrive as a follower of Jesus. The spiritual life is simple in many ways, but potentially the most difficult part of your life. God invites you to grow, to live intentionally and to join in His mission. It's very cool that we can do that together! Thank you for joining me today! “If you're new here, you can check out past episodes at runwithhorses.net. As always, I appreciate your feedback, questions, and reviews!” **(23:00 – 0:00)* *  PART 1 Run With Horses is on the radio! If you are enjoying Run With Horses, would you let someone know? Contact the radio station or leave a review on your favorite app. We want to hear from you! ⸻ Multiplication Thinking Part 1: The Power of the Questions We Ask (Vision & Theology) Theme: Questions reveal what we believe about God's mission, our role, and the future. ** 1. Why Questions Matter **  Questions expose vision (or the lack of it) Show how “addition” questions limit scope vs. “multiplication” questions which expand possibilities.  Example: “How many people can I gather?” (Level 2 thinking) vs. “How many disciple-makers can I release?” (Level 4-5 thinking). .The Five Levels of Church Mutiplication 1.subtraction 2. Plateau 3.addition 4. Reproducing 5. Multiplication . *** 2. The Five Levels of Leadership (from Hero Maker) ***  • Level 1: I count (thinking addition, personal results).  • Level 2: I count what I do (improving programs).  • Level 3: I count what we do together (team success).  • Level 4: I count leaders I raise up (reproduction).  • Level 5: I count leaders who multiply leaders (movement/multiplication).  • Use examples of how each level asks progressively bigger questions. *** 3. Biblical and Theological Foundation *** .  • Jesus modeled multiplication: He invested in 12 → sent 72 → great commission to all.  • Paul's instruction to Timothy: “Entrust to reliable people who will also be qualified to teach others” (2 Tim. 2:2).  • The kingdom grows like a seed — designed for multiplication, not maintenance (parable of the mustard seed, yeast in the dough). *** 4. Why Maintenance Mindset is Dangerous ***  • It keeps leaders in survival mode (protecting what is).  • It makes ministries inward-focused rather than kingdom-focused.  • Ultimately, it limits generational impact. ***  5. Challenge: ***  • What questions are you currently asking in your ministry?  • Are they addition questions or multiplication questions?  • (Good interactive moment: invite participants to write down their top 2 questions they ask about ministry and assess what “level” they reflect.) ⸻ **(00:00) END PART 1** **(27:00 – 5:00) BEGIN PART 2* Part 2: Asking Multiplication Questions  Leaders at every level can shift from addition to multiplication by the questions they ask. *** 1. Shifting the Question at Every Level of Leadership*** .  • Sunday school teacher: Instead of “How many kids will show up?” ask “How many kids can I equip to share their faith?”  • Deacon/volunteer leader: Instead of “How do I fill this need?” ask “Who can I invite and empower to step into leadership?”  • Pastor: Instead of “How do we grow this church?” ask “How do we plant churches and send leaders?”  • Church planter: Instead of “How do I build this church strong?” ask “How do I build this to multiply from the start?” *** 2. Practical Multiplication Questions to Introduce***  • Who am I discipling right now?  • Who could they disciple next?  • What leaders am I raising up?  • Who in my ministry could replace me if I left tomorrow?  • What's stopping me from giving more away? *** 3. Tools & Practices to Reinforce Multiplication Thinking***  • Permission-giving: Start saying “You can do this” more often.  • Scorecards: Redefine success — not just how many are attending, but how many are multiplying.  • Apprenticing model: Always have someone learning beside you. *** 4. Case Studies / Stories***  • Share short stories of multiplication in action (a teacher who trained kids to lead, a church that planted another church, a small group that reproduced).  • Highlight that multiplication is possible at every level, not just at the top. *** 5. Closing Challenge & Vision Casting***  • Ask participants: “If every leader here multiplied themselves once in the next 2 years, what would happen in our church and community?”  • Cast vision for generational leadership: thinking in terms of “spiritual grandchildren.”  • Call them to choose one multiplication question they'll start asking this week. *** 6. Sample Multiplication vs. Maintenance Questions*** Sunday School Teachers  • Maintenance: How many kids will show up this week?  • Multiplication: Which kids can I disciple so they can share their faith with others?  • Multiplication: Who could I apprentice as a future teacher? ⸻ Deacons  • Maintenance: How do we meet the needs of our members better?  • Multiplication: Who else can we raise up to serve so more people are empowered?  • Multiplication: How do we multiply servant leaders, not just serve needs? ⸻ Sound Booth / Tech Team  • Maintenance: How do I make sure the sound and slides run smoothly this Sunday?  • Multiplication: Who can I train so they can run sound in the future?  • Multiplication: How do we multiply tech leaders so new services, campuses, or ministries can launch equipped? ⸻ Worship Leaders  • Maintenance: How do we sound better this Sunday?  • Multiplication: Who in the band or congregation can I mentor to lead worship in the future?  • Multiplication: How do we multiply worship leaders so that every group, gathering, or church plant has someone to lead? ⸻ Pastors  • Maintenance: How do we grow this church bigger?  • Multiplication: How do we raise up pastors and church planters from within?  • Multiplication: Who are my “Timothys” that I'm intentionally training to multiply leaders? ⸻ Church Planters  • Maintenance: How do I make this church strong and healthy?  • Multiplication: How do I plant in such a way that this church will plant another church within 3 years?  • Multiplication: How do I build a culture of sending from the very beginning? ⸻ General “Every Leader” Questions  • Maintenance: How do I succeed in my role?  • Multiplication: Who am I apprenticing to take my place?  • Multiplication: Who are my spiritual grandchildren — the people being discipled by those I discipled? ⸻ ***  7. Progression of Questions: From Addition to Multiplication*** Level 1: I Count (self-focused)  • How am I doing?  • Did I do a good job teaching / leading / serving?  • Did people like what I did today? (Example: A sound booth worker asks, “Did I get the slides right?”) ⸻ Level 2: I Count What I Do (program-focused)  • How many people showed up to my class, service, or ministry?  • How can I make this better for those who attend?  • Did the event/service/program run smoothly? (Example: A Sunday school teacher asks, “How many kids are in my class this week?”) ⸻ Level 3: I Count What We Do Together (team-focused)  • How is our team doing?  • How can we grow this ministry bigger or better together?  • How can we serve more people as a team? (Example: A deacon asks, “How can our deacon team meet more needs this year?”) ⸻ Level 4: I Count Leaders I Raise Up (reproduction-focused)  • Who am I apprenticing right now?  • Who could I trust to lead if I wasn't here?  • How can I release more people into ministry and leadership? (Example: A worship leader asks, “Who in the band can I mentor to lead a worship set?”) ⸻ Level 5: I Count Leaders Who Multiply Leaders (movement-focused)  • Who are my spiritual grandchildren — the leaders raised up by the leaders I've discipled?  • How do we create a culture where leaders naturally multiply leaders?  • How can we measure success by kingdom expansion, not just local growth? (Example: A pastor asks, “Who are the church planters being trained by the leaders I've already raised up?”) ⸻ ✅ Progression Summary (for a slide or handout):  • Level 1–2 questions: focus on me and my ministry.  • Level 3 questions: focus on our ministry team.  • Level 4 questions: focus on leaders I raise.  • Level 5 questions: focus on leaders who raise leaders.   **(1:00)**  What kinds of questions are you asking? Do your answers move you toward reproduction and multiplication or do they keep you stuck in the status quo? I know what kind of questions I want to be asking! – “Thank you for listening today!  -If you enjoyed the show you can listen to all the past shows wherever you listen to podcasts. A good place to start is at runwithhorses.net. You can also write me at norman@runwithhorses.net or leave a comment on the Run With Horses Podcast facebook page. Don't be discouraged by the challenges you face. Keep your eyes on Jesus and embrace the opportunity to grow through the trial. Until next time, keep your eyes on Jesus and never stop running." **(00:00)**

Toronto Argonauts linebacker Wynton McManis joined OverDrive to discuss his position on the field, understanding the opponent's defensive scheme, Ryan Dinwiddie's clash with the Elks, the matchup against the Alouettes and more.

Send us a textIn this episode, Rich sits down with Chris Holloway, the founder of the Midwest Overland & Off-Road Expo (MOORE) in Springfield, Missouri. Chris shares his unlikely path from ice cream truck entrepreneur and diesel tech to building one of the Midwest's premier overland and off-road trade shows. Highlights - From Massachusetts to Missouri: family, music roots, and early hustle - The “40 Licks” ice cream truck, party wagons, and learning business young - Tech school turnaround: graduating top of his class in diesel electronics - Grease to growth: from shop broom to youngest service manager running a dealership - First rigs, JK life, and discovering community through wheeling and camping - Throwing trail events, fundraising, and the mentor who sparked MOORE Expo - Launching MOORE: 50 vendors, 2,000 attendees, then doubling during COVID - Vendor retention, event fatigue, and why brands cycle regions - Expanding into PowerSports and the “dot…dot…dot” of overlanding (hiking, hunting, bikes, kayaks, shooting sports) - What's next: big reinvestments and a major reimagining post-2026 Event + Contact - MOORE Expo: April 17–18, 2026 — Springfield, MO - Info/Vendors: mooreexpo.com (contact form goes to Chris) - Email: chris@mooreexpo.com Support the show

BUFFALO, NY — September 18, 2025 — A new #research paper was #published in Volume 17, Issue 8 of Aging-US on August 9, 2025, titled “The myokine FGF21 associates with enhanced survival in ALS and mitigates stress-induced cytotoxicity.” In this study, led by first author Abhishek Guha and corresponding author Peter H. King from the University of Alabama at Birmingham and the Birmingham Veterans Affairs Medical Center, researchers discovered that a hormone called FGF21, which is released by muscles, is elevated in people with amyotrophic lateral sclerosis (ALS) and may play a protective role. These findings are especially relevant because ALS is a fatal and currently incurable neurodegenerative disease. Amyotrophic lateral sclerosis is an age-related and progressive condition that affects the nerve cells responsible for muscle control. While some treatments can slow the disease, there is still a need to understand why ALS progresses at different rates in different individuals. “In a prior muscle miRNA sequencing investigation, we identified altered FGF pathways in ALS muscle, leading us to investigate FGF21.” The research team analyzed muscle biopsies, spinal cord tissue, and blood samples from ALS patients and found that FGF21 levels were significantly elevated. This increase was particularly evident in atrophied muscle fibers—those that had shrunk due to nerve loss—and in the surrounding tissue. Importantly, patients with higher plasma levels of FGF21 showed slower loss of function and longer survival, with some living more than six years after diagnosis. Using animal models and cultured cells, the researchers demonstrated that FGF21 levels rise even in the early, symptom-free stages of ALS. The hormone appeared to protect both muscle and motor neurons from stress-related damage. When added to stressed cells, FGF21 improved cell survival and reduced markers of cell death. In human muscle cells, FGF21 also supported the formation of new muscle fibers, a process known as myogenesis. Blood tests revealed that patients with higher levels of FGF21 not only experienced slower disease progression but also tended to have a higher body mass index (BMI), a factor previously associated with longer survival in ALS. This suggests that FGF21 may reflect a patient's ability to counteract ALS through natural protective mechanisms. It could also serve as a biomarker to monitor disease severity and potentially guide treatment decisions. The study also investigated how FGF21 communicates with cells. It found that the hormone's activity depends on a protein called β-Klotho, which was also altered in ALS-affected tissues. These changes were especially noticeable in motor neurons and muscle cells under stress, further highlighting FGF21's role in the body's response to damage. While the study does not show that FGF21 can be used as a treatment, it highlights the hormone as a promising target for future research, clinical trials, and strategies to slow ALS progression by leveraging the body's natural protective systems. DOI - https://doi.org/10.18632/aging.206298 Corresponding author - Peter H. King - phking@uabmc.edu Abstract video - https://www.youtube.com/watch?v=zEGMxQrxZxE Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, fibroblast growth factor, 21 β-Klotho, ALS biomarker, human skeletal muscle, motor neurons To learn more about the journal, please visit our website at https://www.Aging-US.com​​ and connect with us on social media at: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Bluesky - https://bsky.app/profile/aging-us.bsky.social Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

The episode dives into the Los Angeles Chargers' strong start to the season, highlighting their impressive 2-0 record and focusing on the Chargers' dominant defense, which has consistently held opponents under 21 points. They analyze the “complementary football” the Chargers are playing, with offense, defense, and special teams working seamlessly together. Looking ahead to the upcoming matchup against the Denver Broncos, they explain why the Chargers may anticipate relying more on their running game and maintaining a physical approach against Denver's strong defensive line. They also emphasize the importance of this divisional game, as it could place the Chargers in a favorable position for the AFC West title. 0:00:16 – Chargers' Hot Start to the Season Matt Money Smith and Lorenzo Neal celebrate the Chargers starting 2-0, Justin Herbert's MVP odds, and early season excitement. 00:00:58 – Defensive Dominance & Complimentary Football Lorenzo details the elite level of the Chargers' defense, how holding teams under 21 points leads to wins, and their strong all-around play. 00:02:02 – Monday Night Game Breakdown: Chargers vs Raiders Matt analyzes the Chargers' defensive adjustments against the Raiders, the trouble for the Raiders' offense, and how Brock Bowers' injury impacted the game. 00:03:34 – Chargers' Defensive Schematics and Player Performances Discussion of pressure rates, standout performances by rookies like Jamaree Caldwell, and praise for defensive coaches. 00:07:39 – Pass Rush Techniques & Interior Line Impact Lorenzo expands on the importance of Derwin James, game-ball-worthy interior linemen, and specifics on disrupting opposing quarterbacks. 00:09:55 – Limiting Explosive Plays Matt and Lorenzo discuss how the Chargers defense forced the Raiders into short gains, allowing zero passes over 20 yards. 00:14:00 – Chargers' In-Game Adjustments & Finishing Drives Strategic decisions in the red zone, defensive resilience in long drives, and clock management insights. 00:18:00 – Standout Defensive Plays: Derwin James' Impact Detailed praise of Derwin James' sideline-to-sideline play and physical dominance. 00:22:19 – Taking the Raiders' Will: Physical & Mental Edge Lorenzo talks about how the Chargers “took the Raiders' heart” and the psychological side of a dominant defense. 00:23:17 – Daiyan Henley's Flu Game Recognition of Daiyan Henley's standout, Pro Bowl-worthy performance despite being sick. 00:25:53 – Tony Jefferson & Safety Depth Debate about why Tony Jefferson, a key playmaker, hasn't been promoted from the practice squad. 00:30:35 – Khalil Mack Injury Update & Next Man Up Positive news on Khalil Mack, discussion on depth options at edge rusher, and praise for the coaching staff's flexibility. 00:33:54 – Coaching Adjustments & Depth Contributions How cross-training players and quick in-game adjustments help overcome injuries. 00:35:48 – Herbert's Progression & Poise Evaluating Justin Herbert's composure, playmaking abilities, and how continuity is benefiting him. 00:39:03 – Wide Receivers & Explosive Passing Plays Catching up on Q, Keenan, and McConkey's impact and how the passing attack has evolved. 00:42:32 – Offensive Line & Pass Protection Breakdowns Matt details a crucial fourth down conversion, attributing it to the work of Matlock and Omarian Hampton in protection. 00:45:30 – Running Game: Najee Harris & Hampton Discussions about balancing the run game, differences in veteran vs rookie backs, and red zone play calling. 00:50:55 – Offensive Line: Backside Cutoff Struggles Breakdown of specific run plays that faltered, particularly in handling Maxx Crosby. 00:54:33 – Denver Broncos Preview: Defensive Fronts Preview of Denver's formidable defensive line and the tactical considerations for the upcoming game. 00:58:52 – Broncos' Weaknesses, Strategy, & Coaching Analyzing where the Broncos have faltered, Indy's blueprint, and what the Chargers need to do. 01:00:02 – Division Stakes & Playoff Implications the magnitude of a potential 3–0 division start and how it affects standings. 01:04:53 – Rivalries & Coaching Personalities 01:06:00 – Looking Ahead: Tough Schedule & Season Outlook Addressing the rest of the Chargers' schedule and the importance of capitalizing on the current momentum. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Other Episodes You Might Like: Previous Episode - Riding Tandem: One Couple, One Mission, One Bike From Mexico to Alaska Next Episode - 5 Ways to Measure & Improve Your Menopause Fitness At Home Right Now More Like This - What They Don't Teach Women About Strength Training and should   Resources: Join the Hot, Not Bothered! Challenge to learn why timing matters and why what works for others is not working for you. Use Flipping 50 Scorecard & Guide to measure what matters with easy at-home self-assessment test you can do in minutes. Don't know where to start? Book your Discovery Call with Debra. Leave this session with insight into exactly what to do right now to make small changes, smart decisions about your exercise time and energy.   Scrolling through social media, it can be a challenge to understand the truth about muscle and menopause.  This episode evidence-based menopause fitness programming on how to build muscle in menopause, why you're losing muscle in menopause, whether hormone therapy prevents muscle loss, and what research exists on menopause muscle research.  We answer questions by someone who isn't just “doing his research,” but has and continues to conduct studies to find the truth about muscle and menopause.   My Guest: Dr. Stuart Phillips is a Distinguished University Professor in the Department of Kinesiology and a member of the School of Medicine at McMaster University. He is a Tier 1 Canada Research Chair in Skeletal Muscle Health. Dr. Phillips' work centers on the interaction of exercise/physical activity, aging, and nutrition in skeletal muscle and body composition. Dr. Phillips is a fellow of the Royal Society of Canada, the American College of Sports Medicine and the Canadian Academy of Health Sciences.   Connect with Dr. Stuart: Instagram - @mackinprof Facebook - Stuart Phillips, Ph.D. X -  @mackinprof LinkedIn - Dr. Stuart Phillips TikTok: @mackinprof   Questions We Answer in This Episode: [00:10:18] Does lifting heavier or lighter weights work best for women in menopause? [00:16:34] When do women reach adrenal fatigue?      [00:19:39] Does use of Hormone Therapy prevent or mitigate muscle loss during menopause? [00:21:55] Do women lose more muscle during menopause than expected based on age?                  [00:24:22] How is Zone 2 exercise specifically beneficial for women, in menopause or otherwise?  [00:29:00] Are weighted vests useful for women, in perimenopause or otherwise? [00:42:20] What is the best timing for protein intake? [00:48:10] What's true about pre-exercise vs. post-exercise nutrition for women and supporting their goals? What are your thoughts on women who are under-eating and are training?

durée : 00:02:41 - 100% PSG - Le billet - Parmi les joueurs qui ont joué toutes les rencontres cette saison, on trouve le jeune Ibrahim Mbaye. À 18 ans, Luis Enrique semble lui faire confiance malgré un manque de progression dans ces performances depuis un an. Que doit-il faire pour avoir son déclic en pro ? Vous aimez ce podcast ? Pour écouter tous les autres épisodes sans limite, rendez-vous sur Radio France.

Episode 210 of The Adventure Podcast features polar guide, explorer, and adventurer Sarah McNair-Landry. Growing up in Iqaluit on Baffin Island with parents who pioneered polar guiding, Sarah's childhood was shaped by dog sledding, camping, and life in the Arctic wilderness. In this episode, Matt and Sarah explore her journey from early expeditions to guiding at the North and South Poles, the unique challenges of dog sledding and kite skiing, and how she and her partner Boomer combine kayaking, climbing, and polar travel into bold multi-sport expeditions. They touch on themes of resilience, heritage, adventure for adventure's sake, and the delicate balance between tourism, culture, and conservation in the North. Sarah reflects on recreating her parents' legendary circumnavigation of Baffin Island, how growing up in an Inuit community shaped her, and why, despite the hardships, she continues to push further into remote landscapes. This is a story of family legacy, human endurance, and finding joy in the harshest environments on Earth. It's an episode that will make you want to pack your sled and chase the wind.For extra insights from the worlds of adventure, exploration and the natural world, you can find The Adventure Podcast+ community on Substack. You can also follow along and join in on Instagram @‌theadventurepodcast.Chapter Breakdown:00:00 – 06:30 | Growing up in Iqaluit: childhood in the Arctic, parents as polar guides, and early exposure to outdoor life.06:30 – 12:30 | Progression into expeditions: dog sledding, kite skiing, and first North and South Pole journeys.12:30 – 18:30 | Dog sledding vs. skiing: the dynamics of working with animals, expedition challenges, and recreating her parents' 1990 Baffin Island circumnavigation.18:30 – 24:30 | Expedition mishaps and resilience: kite skiing accidents, breaking her back in Greenland, and pushing through setbacks.24:30 – 31:30 | Multi-sport exploration: combining polar travel with kayaking, climbing, and the appeal of first descents.31:30 – 37:30 | Adventure at home: affordability of Arctic expeditions, rediscovering the backyard, and the accessibility of Baffin and Greenland.37:30 – 44:30 | Tourism and community: the opportunities and challenges of opening Nunavut to more visitors.44:30 – 47:00 | Partnerships and teamwork: traveling with Boomer, team dynamics, and the importance of good expedition partners.47:00 – 52:00 | Culture and identity: growing up white in an Inuit community and how it shaped her outlook.52:00 – 57:00 | Life balance: guiding, running a business, time outdoors vs. computer work, and the changing role of tech like Starlink in remote expeditions.57:00 – 01:04:40 | Reflections: the future of polar travel, fear of snakes and heights, learning to climb, and finding hope in people who care about the planet.Support this show http://supporter.acast.com/the-adventure-podcast. Hosted on Acast. See acast.com/privacy for more information.

Senescent cells were supposed to be the "easy" target in aging research—clear them out and extend healthspan. But new research reveals the field is far more complex than anyone imagined, with major clinical trial setbacks forcing scientists to completely rethink their approach.Some links are affiliate links so we will earn a commission when they are used to purchase products.In this conversation with Dr. Paul Robbins from the University of Minnesota, we explore the evolving world of senescent cell research and senolytics—drugs designed to clear "zombie" cells from our bodies. Dr. Robbins reveals how recent research shows senescence is far more complex than expected, with different types arising from different stresses. We discuss why Unity Biotech's trials failed, mixed results from fisetin studies, and surprising positive signals from Mayo Clinic trials in patients with high senescent cell burden. He explains why future treatments will require personalized cocktails of different senolytics, the potential of alternative approaches, and why he remains optimistic despite setbacks. Dr. Robbins also shares insights into next-generation compounds his lab is developing and hints at positive clinical trial results coming soon.

Send us a textGuitarist Mike Shouse Returns With New Album "Jaded," Bringing Along Fellow Axe Slingers#newmusic #indiemusic #guitarist #podcast #newalbum Shouse was born Michael Stephen Shouse on September 27th, 1970 in Jackson, KY. In 1992 he moved to LA and attended the Guitar Institute of Technology in Hollywood, CA. He has written articles and lessons for online sites such as chopsfromhell.com and guitar9.com, and has been featured in magazines like Progression, Fireworks and The Sound guitar magazines. He released “Enter the Soul” in 2001 and the song “Man” was on a compilation CD “International Anthems: Volume 1” in 2002. His second release Alone on the Sun was released in June 2010 and got rave reviews worldwide. The title track “Alone on the Sun” was featured on the new compilation cd “Gods of Indie Guitar 2011” and premiered on the Australian tv show “Guitar Gods and Masterpieces.”Jaded is his first release in 15 years and he's back with friends! Featuring guest solos from legends Michael Angelo Batio, Ron “Bumblefoot” Thal and Tony MacAlpine. Filling out the band on drums, the best of the best, from NY, Charlie Zeleny (Drumageddon, Jordan Rudess and Terry Bozzio). Playing bass, from Los Angeles, James Amelio Pulli (Metal Hall of Fame bassist for Impellitteri). Mixed and mastered by Nashville legend Billy Decker. As Shouse states, “This album is a rebirth for me in many ways,” and critics from around the world are taking notice.Get your copy here: https://www.dekoentertainment.com/inthesquare/mike-shouseWebsite: https://mikeshousemusic.com/Facebook: https://www.facebook.com/people/SHOUSE-MUSIC/100038883613071TikTok: https://www.tiktok.com/@mike.shouseInstagram: https://www.instagram.com/shouse_mikeX: https://x.com/mikeshouse60101YouTube: https://www.youtube.com/@mikeshouseguitarSpotify: https://open.spotify.com/album/1KhZgd7ke8hzH58X0qtrctThanks for tuning in, please be sure to click that subscribe button and give this a thumbs up!!Email: thevibesbroadcast@gmail.comInstagram: https://www.instagram.com/listen_to_the_vibes_/Facebook: https://www.facebook.com/thevibesbroadcastnetworkLinktree: https://linktr.ee/the_vibes_broadcastTikTok: https://vm.tiktok.com/ZMeuTVRv2/Twitter: https://twitter.com/TheVibesBrdcstTruth: https://truthsocial.com/@KoyoteFor all our social media and other links, go to: Linktree: https://linktr.ee/the_vibes_broadcastPlease subscribe, like, and share!

In Episode 20 of The Luke Coutinho Show, we dive deep into the world of Alzheimer's disease—a condition feared by many but one that can often be prevented or slowed with the right lifestyle choices.Here's what you'll explore in this episode:The science behind Alzheimer's disease and how it disrupts brain function.The role of neurons, glial cells, and the glymphatic system in brain health.How sleep, movement, and circulation influence memory and cognition.The impact of chronic inflammation, beta-amyloid plaques, and gut health on Alzheimer's progression.Key nutrition strategies: healthy fats, Omega-3s, Vitamin B12, CoQ10, and more.Practical lifestyle pillars—nutrition, sleep, exercise, emotional wellness, and circadian rhythm alignment—to prevent or slow Alzheimer's.And much more…

Osteosarcoma Webinar Series: Yanding Zhao, PhD to discuss how Distinct patterns of chromosomal instability fuel osteosarcoma progression and influence patient outcomes.Osteosarcoma (OS) is notable for extreme chromosomal instability (CIN) and molecular heterogeneity, which have hindered therapeutic progress. To address this, the lab performed longitudinal and multi-modal profiling of 91 tumors from 71 pediatric patients, integrating whole-genome and transcriptome sequencing with ATAC-seq and Hi-C in matched cell lines. Their analyses revealed that key driver mutations, including TP53, are fixed early and persist through progression. Over 80% of tumors exhibited complex structural alterations—such as chromothripsis, kataegis, loss of heterozygosity, and ecDNA amplification—with MYC enhancer hijacking linked to chemoresistance. They identified a high-risk evolutionary trajectory marked by homologous recombination deficiency (HRD)-like signatures in the absence of BRCA mutations. These tumors showed focal duplications at fragile sites, early whole-genome doubling, high TP53 mutation burden, and sensitivity to PARP inhibition—highlighting a potential therapeutic vulnerability. Together, these findings define a replication stress–driven model of OS evolution, shaped by early chromosomal remodeling and ecDNA-mediated oncogene activation, with implications for biomarker development and precision treatment strategies.Dr. Yanding Zhao is a postdoctoral researcher at Stanford University in the lab of Dr. Christina Curtis. He earned his PhD in Genetics from Dartmouth College, where he began developing computational tools to understand how genome instability disrupts gene regulation in cancer. At Stanford, his research focuses on pediatric osteosarcoma. By combining genome sequencing, 3D chromatin mapping, and spatial transcriptomics, he studies how tumors evolve, resist treatment, and evade the immune system. Dr. Zhao works closely with clinicians and scientists to help turn these discoveries into potential new therapies. He is honored to be part of the MIB Agents community and looks forward to sharing his work in a way that resonates with patients, families, and advocates.

Gametime Ticket Offer: $20 off with code "FARZY" at gametime.co The Farzy Show presented by MyBookie Promo: No-strings-attached cash bonus up to $200 Promo Codes: FARZY ..  https://mybookie.website/joinwithFARZYManscaped Offer: 20% off AND Free Shipping with code "Farzy20" at Manscaped.comCopyright Disclaimer under section 107 of the Copyright Act 1976, allowance is made for “fair use” for purposes such as criticism, comment, news reporting, teaching, scholarship, education and research. Fair use is a use permitted by copyright statute that might otherwise be infringing.

La myopie chez les enfants progresse rapidement : d'ici 2050, une personne sur deux pourrait être concernée. Ce trouble de la vision, souvent détecté tardivement, entraîne une vision floue de loin et peut évoluer fortement pendant l'enfance.Dans cet épisode de Papatriarcat, réalisé en partenariat avec Krys et Hoya, nous explorons les causes, les signes précoces et les solutions pour accompagner les familles. Avec Charlotte Duyck, opticienne spécialisée en basse vision, et Alexandra Martin, maman d'une enfant myope, nous abordons :Comment reconnaître les premiers signes de la myopie.Les facteurs de risque (génétique, environnement, usage des écrans, manque d'activités extérieures).Les solutions existantes pour corriger et freiner l'évolution de la myopie, comme le verre innovant MiYOSMART de Hoya, disponible chez Krys (sous prescription médicale).Le quotidien des familles : choix des lunettes, suivi médical, activités sportives.Les gestes simples pour prévenir la progression, comme la règle du 20-20-20. Question fréquente : Peut-on vraiment freiner la myopie de l'enfant ?→ Oui, grâce à des innovations cliniquement prouvées comme les verres MiYOSMART. Il corrige la vue tout en freinant l'allongement de l'œil, avec l'appui d'un suivi médical adapté. Nous sommes ravis de vous proposer cet échange qui croise l'expertise professionnelle et l'expérience parentale pour éclairer un sujet de santé publique majeur et donner des clés concrètes aux familles.Cet épisode a été réalisé en partenariat avec Krys et Hoya.Les lunettes correctrices sont des dispositifs médicaux qui constituent des produits de santé réglementés portant le marquage CE. Demandez toujours conseil à un professionnel de santé ou à votre opticien.Le verre MiYOSMART est délivré uniquement sur ordonnance d'un ophtalmologiste.Les opinions exprimées dans cet épisode n'engagent que les intervenant·es.Pour en savoir plus, reportez-vous aux conseils disponibles en magasin ou sur krys.com/sante .Salutations adelphes et solidaires ! Cédric Etudes citées :Progression of myopia in children and teenagers : a nationwide longitudinal studyGlobal Prevalence of Myopia and High Myopia and Temporal Trends from 2000 through 2050,The real-world effectiveness of defocus incorporated multiple segments and highly aspherical lenslets on myopia control: a longitudinal study from the French myopia cohort *******************************************Crédit musiques : www.bensound.comCrédit dialogue : BRUT - le sexisme chez les enfants (youtube)Plus d'informations sur krys.com/santeSoutenez ce podcast http://supporter.acast.com/papatriarcat. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

The search for excellent dental assistants can be tough. Just like hygienists, many of them are searching to work to the top of their scope and be compensated accordingly. In this episode, Rachael Wintersteen joins the show to talk about what drives her to continue to search for excellence and promotion. 

TSN Baseball Insider Steve Phillips joined OverDrive to discuss the Blue Jays' electric walk-off win against the Astros, Vladimir Guerrero Jr.'s impressive plays in the game, playing through Bo Bichette's injury on the roster, John Schneider's perspective for the team, Shane Bieber's progression and more.

It's another MiOsc episode on martial arts and fitness progression. The truth of any discipline is that progress is not a straight line. We discuss the importance of understanding your "why"—the core motivation that fuels your training. The post 430. MiOsc on martial arts progression first appeared on Sifu Mimi Chan.

Joby Aviation (JOBY) rallied earlier today on an announcement that Uber Technologies (UBER) will feature Blade air mobility services on its app. As George Tsilis explains, it's a win for Joby, though the stock needs something more if it's to fly back to all-time highs.======== Schwab Network ========Empowering every investor and trader, every market day. Subscribe to the Market Minute newsletter - https://schwabnetwork.com/subscribeDownload the iOS app - https://apps.apple.com/us/app/schwab-network/id1460719185Download the Amazon Fire Tv App - https://www.amazon.com/TD-Ameritrade-Network/dp/B07KRD76C7Watch on Sling - https://watch.sling.com/1/asset/191928615bd8d47686f94682aefaa007/watchWatch on Vizio - https://www.vizio.com/en/watchfreeplus-exploreWatch on DistroTV - https://www.distro.tv/live/schwab-network/Follow us on X – https://twitter.com/schwabnetworkFollow us on Facebook – https://www.facebook.com/schwabnetworkFollow us on LinkedIn - https://www.linkedin.com/company/schwab-network/ About Schwab Network - https://schwabnetwork.com/about

Hosts: Dr. Ashlee Gethner, LCSW – Child of a Police Officer Jennifer Woosley Saylor, LPCC S – Child of a Police Officer Guest: Marian Cosgrove - Army Veteran and Law Enforcement Officer Episode Overview: In this deeply honest and powerful episode, hosts Jennifer and Ashlee sit down with Marian Cosgrove, an Army veteran, long-serving law enforcement officer, and survivor, to talk about substance abuse among first responders. Marian shares her personal journey from childhood trauma, through years of high-functioning alcoholism, to eventual recovery. She discusses the cultural normalization of substance use in law enforcement, the challenges of recognizing when coping has become addiction, and the importance of self-reflection and support. Marian opens up about the root causes of her substance abuse, the process of self-honesty, hitting rock bottom, and the life-changing role of therapy and 12-step programs in her recovery. The conversation also touches on the impact of unresolved pain from childhood, why coping mechanisms develop, and how compartmentalization can be both protective and harmful. Key Topics Covered The Hidden Prevalence of Substance Use:  Why substance abuse is so common among first responders and how drinking becomes normalized as a way to cope with trauma and emotional suppression. Marian’s Story: From a significant childhood trauma (including her struggle to be heard and believed), to coping with discomfort through alcohol use, Marian details how her journey diverged into high-achievement while battling feelings of being an outsider and never quite fitting in. Where is the Line?: We explore the blurry line between social drinking and alcoholism, and how it’s not always clear. Especially for high-functioning individuals. Self-reflection and honesty are critical. Compartmentalization and Childhood Impact: The conversation emphasizes how early experiences and learned coping tactics can shape adult behaviors, especially in high-stress careers. Functional Alcoholism & Progression: Marian describes how her drinking escalated slowly over decades, how she rationalized her habits, and how the "incremental elevator" of standards slides over time. Reaching Out and Support: After her life spiraled, Marian sought help through a treatment program and AA, acknowledging the difficulty and necessity of vulnerability and community among those with lived experience. Changing Coping Mechanisms: Using the concept of “neuro-bypasses” (habitual pathways in the brain), Marian explains how long-term coping with substances becomes deeply ingrained, and how therapy and group support helped her forge new habits. Impact on Family & Children: The group discusses how first responder stress and substance use can affect families, particularly children who may internalize emotional disconnection at home. Advice for Listeners: Marian encourages anyone struggling with substance abuse to reach out, listen to others’ stories, seek both peer and professional support, and understand that recovery is possible.   If this episode resonated with you or if you have stories to share about living with a first responder, reach out to Ashlee and Jennifer on their social media platforms!   Thank you for tuning in! Don't forget to subscribe, rate, and review "When The Call Hits Home" on your favorite podcast platforms!   Follow Us: - Facebook: When The Call Hits Home Podcast - Instagram: @whenthecallhitshome - Whenthecallhitshome.com --- This podcast does not contain medical / health advice. It is not intended to be a substitute for professional medical or mental health advice, diagnosis or treatment and should not be relied on as health or personal advice. The information contained in this podcast is for general information purposes only. The information is provided by Training Velocity LLC and while we endeavour to keep the information up to date and correct, we make no representations or warranties of any kind, express or implied, about the completeness, accuracy, reliability, suitability or availability with respect to the Podcast or the information, products, services, or related graphics contained in the podcast for any purpose. Any reliance you place on such information is strictly at your own risk.  WE ARE NOT RESPONSIBLE NOR LIABLE FOR ANY ADVICE, COURSE OF TREATMENT, DIAGNOSIS OR ANY OTHER INFORMATION, SERVICES OR PRODUCTS THAT YOU OBTAIN THROUGH THIS PODCAST.  Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have heard on this podcast.

Are the Patriots failing Drake Maye? // Tom King of the Nashua Telegraph joins the show

SERMON PODCAST NOTESSeries: RootedWeek 1 Title: Introduction – Rooted vs. RootlessScripture: Psalm 1:1–6Big Idea: The blessed life isn't found in being potted but in being planted—rooted in God, drawing strength from His Word, His people, and His purpose.I. Two Ways to LiveThe righteous: rooted, fruitful, enduring, blessed by God.The wicked: rootless, unstable, blown away like chaff.Psalm 1 frames the entire book of Psalms as a wisdom gateway.II. The Progression of CompromiseWalk with the wicked → Stand with sinners → Sit with mockers.Influence shapes destiny. Who you walk with, sit with, and do life with matters.Fool = adjusts truth to fit behavior. Wise = adjusts behavior to fit truth.III. Rooted vs. RootlessRooted: a tree by streams of water—strong, stable, life-giving.Rootless: chaff—weightless, useless, gone in a moment.Illustration: Biosphere 2 — without wind, trees looked healthy but collapsed. Resistance produces roots.IV. Planted or Potted?A planted tree = deep roots, stable, fruitful.A potted plant = shallow, surface-level, easily uprooted, limited growth.Living potted is safer, but never fruitful. True life comes from deep roots.Illustration: Mentor who planted gardens even in temporary homes—lived with the long game in mind.V. The Choice is YoursDeuteronomy 30:19 — Choose life or death, blessing or curse.Jesus doesn't make life easier—but He makes it better, meaningful, worth it.Decide: “I'm not going to be potted. I'm going to be rooted.”

Russ Hosmer, a U.S. Marine Corps veteran, certified life coach, former national-champion bodybuilder, and founder of Constant Progression, an online life coaching and personal development platform serving clients worldwide, joins Discover Lafayette to discuss his mission to help others reach their full potential. Russ grew up in New Jersey, just outside of New York City. At 17, his parents retired and moved to Alabama. He studied at Jacksonville State University and worked in health club turnarounds: “We found the gyms and the health clubs that were in the red, and we brought them into the black. We got the management together, the business side of it, and got them better and rolling.” Russ was a bodybuilder alongside business: “I was a state champion when I was a teenager… top five in the national championship. I was a national champion twice. Two times. Two years in a row as the first one to ever do that.” That era cemented discipline: “I was blessed. I was doing what I love… when you do that, you don't ever work a day in your life.” Choosing the Marines, Special Operations, and What Service Really Looked Like “My family is Marine Corps. My grandfather was a WWII veteran and my brother was a Marine… it was almost like, well, I have to do that.” He enlisted on a whim, calling it “probably the greatest decision of my life.” Boot camp at Parris Island: “They start drilling leadership principles into you the day you get there… It's a transformation process. It's the title,, being a Marine. So you have to earn it.” After graduating top of his class in the School of Infantry, he went to amphibious reconnaissance / special operations: “We're like 1% of the Marine Corps.” Operational reality: “Less than 1% of the Marine Corps see combat. We do more hospitable missions than we do combat missions. It's urban warfare, small unit tactics. We don't actually fight other countries like uniform military. it's a different world we live in.” He traveled extensively: “I was in 37 countries in three years. I was deployed a lot. But I volunteered because that's what I wanted to do.” PTSD, Loss, and a Five-Year Turning Point Russ is candid: “I do have severe PTSD… I didn't know I had it for years. Then all of a sudden, it was really bad.” Compounding events:“I lost my corporate job during COVID. I had been a senior executive of a Fortune 500 company for twenty years. Then my dad died, and my mom died, then my older brother died." It left him “in a very dark place, kind of lost." "I decided, you know what? I need to help people overcome the PTSD, get the resilience and the mindset, and learn how the mind works and how the body works. And why is this happening?" On the rate of veterans committing suicide, Russ says, “They say it's 22 a day. There's a lot more than that. They don't have help, they think it's a sign of weakness. But you admitting it and talking about it, that's a sure sign of strength.” From a five-year journey, he created Constant Progression: “We're always looking to be our best self. We're all on that journey of constant progression.” Training the Marines & A Vanderbilt Recovery Study That “Changed Everything” After instructing at Marine Corps Recruit Depot Parris Island, Russ became a Physical Training Advisor for the Eastern Recruiting Region—“anything east of the Mississippi River… the whole East Coast.” His remedial programs “went before Congress and they actually enacted those into standard operating procedures… now a part of the Marine Corps training standards.” Russ helped run a muscle recovery study with Vanderbilt University to reduce injuries and attrition: “We had a lot of lower body extremities' injuries, especially with the female recruits… hip fractures and femur fractures, tibia fractures… kids nowadays… they don't eat well.” Findings touched hydration, chow hall practices, food quantity by body weight, and training tweaks (including pull-up progression): “The best way t...

“All of these TKIs [tyrosine kinase inhibitors] inhibit BCR-ABL1 in some way, shape, or form. When BCR-ABL1 is mutated, it has uncontrolled tyrosine kinase activity, leading to rapid cell proliferation. When we then inhibit that BCR-ABL1 that's been mutated, we disrupt this abnormal signaling pathway that drives CML [chronic myeloid leukemia] cell proliferation and survival, ultimately leading to decreased cancer cell growth, increased apoptosis or cell death, and potentially inducing a disease remission,” Samantha Maples, PharmD, BCOP, clinical pharmacy specialist supervisor for hematology and cellular therapy at Allegheny Health Network in Pittsburgh, PA, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about the BCR-ABL1 inhibitor drug class.   Music Credit: “Fireflies and Stardust” by Kevin MacLeod  Licensed under Creative Commons by Attribution 3.0   Earn 0.5 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by September 5, 2026. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation.  Learning outcome: Learner will report an increase in knowledge related to the use of BCR-ABL1 inhibitors in the treatment of CML. Episode Notes   Complete this evaluation for free NCPD.  ONS Podcast™ episodes: Pharmacology 101 series Episode 322: Nursing Strategies to Reduce Readmission Rates for Patients With Cancer Episode 215: Navigate Updates in Oral Adherence to Cancer Therapies ONS Voice articles: Adherence to Oral Anticancer Medication Combination Therapy Shows Promise for Chronic Myeloid Leukemia The Case of the Medication Modification The Case of the Safety Session ONS course: Safe Handling Basics Clinical Journal of Oncology Nursing articles: Targeted Drug Therapies: Beyond Blood Counts and Chemistries Oncology Nursing Forum articles: Adherence and Coping Strategies in Outpatients With Chronic Myeloid Leukemia Receiving Oral Tyrosine Kinase Inhibitors Fear of Progression in Outpatients With Chronic Myeloid Leukemia on Oral Tyrosine Kinase Inhibitors Other ONS resources: Biomarker Database Financial Toxicity Huddle Card Tyrosine Kinase Inhibitors Huddle Card Oral Anticancer Medication Care Compass: Resources for Interprofessional Navigation Oral Anticancer Medication Learning Library National Comprehensive Cancer Network National Comprehensive Cancer Network patient resources To discuss the information in this episode with other oncology nurses, visit the ONS Communities.   To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library.  To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode  “The IRIS study led to the approval of the BCR-ABL1 and TKI, imatinib, for CML in 2001 and completely changed the landscape of CML treatment. Then came the second-generation BCR-ABL1 TKIs: dasatinib in 2006, quickly followed by nilotinib in 2007. Thereafter came our second-generation, bosutinib, and our first approved third-generation TKI, ponatinib, both in 2012, which was a huge milestone as ponatinib overcomes resistance to the T315 I mutation, which no previously approved TKIs worked against.” TS 2:16 “The newest approved TKI, asciminib, is an allosteric inhibitor that binds to a different pocket on the BCR-ABL kinase via allosteric binding to the ABL myristoyl pocket. It's what's called a STAMP inhibitor, where STAMP stands for ‘specifically targeting the ABL myristoyl pocket.' And while all the TKIs target the BCR-ABL1 binding site, they can also inhibit different off-target kinases. And these differences in off-target inhibition are responsible for some of the different toxicities we see among the TKIs.” TS 4:51 “As a class, common toxicities include nausea; vomiting; diarrhea; cardiac toxicities, including cardiac arrhythmias and congestive heart failure; metabolic abnormalities such as hypercholesterolemia and hypertriglyceridemia; nephrotoxicity; hepatic toxicity; hemorrhaging and bleeding; as well as cytopenia. Individually, some of these agents are more likely to cause certain side effects compared to others, and there are unique toxicities associated with certain TKIs.” TS 8:10 “We've moved to using preemptive loperamide [in our clinic] for the first three days of starting treatment, because it's really hard to get patients to continue to take a medication if they have such severe diarrhea that they end up in the hospital or they're unable to leave their house. A lot of times, we will proactively give patients antiemetics and loperamide to help with the nausea, vomiting, and diarrhea. And then we can back off to an as-needed basis once they've been established on treatment. We can also use medications to help manage long-term complications that can require supportive care, such as statin therapy for high cholesterol, levothyroxine for hypothyroidism, anticoagulants for any venous thromboembolism, and antihypertensive medications for managing any new or worsening high blood pressure.” TS 12:44 “We are continually seeing these agents expand their indications to different lines of therapy, as well as more TKIs being approved for acute lymphoblastic leukemia. For example, asciminib just got approved in the frontline setting within the last year, whereas previously it was only approved in relapsed refractory setting. Last year, imatinib was the first BCR-ABL1 TKI to come out with a commercially supplied suspension option as well, which is huge in the pediatric space and [for] our adult patients who are unable to swallow tablets for other clinical reasons.” TS 21:22 “There is more information being published on the safe discontinuation of these medications with treatment-free remissions, and more information is coming out about who would be eligible and who can have the option to stop these treatments instead of having a lifelong chronic condition requiring continuous treatment. We're seeing more patients in clinical practice be able to stop BCR-ABL1 treatment, which has been a great development in CML.” TS 25:29

In this Q+A episode, we're diving deep into all things cardio and running. From choosing the best cardio modality for your goals, to navigating heart rate training without overcomplicating it, this conversation tackles what actually matters when it comes to building endurance and improving performance. We also discuss how to manage exercise-induced asthma, the benefits of cardio during pregnancy, and how to get started if you're new to running or just getting back into it. Whether you're deciding between treadmill or outdoor runs, trying to balance strength training with cardio, or wondering how nutrition and warmups factor in, we've got practical, real-world advice. Plus, we share insights on the mental side of running—and why yes, you absolutely can be a runner, no matter your body type or experience level. APPLY FOR COACHING: https://www.lvltncoaching.com/1-1-coaching SDE Method app: https://www.lvltncoaching.com/sde-method-app The Fitness League Waiting List https://quest.lvltncoaching.com/project-b Macros Guide https://www.lvltncoaching.com/free-resources/calculate-your-macros Join the Facebook Community: https://www.facebook.com/groups/lvltncoaching FREE TOOLS to start your health and fitness journey: https://www.lvltncoaching.com/resources/freebies Alessandra's Instagram: http://instagram.com/alessandrascutnik Joelle's Instagram: https://www.instagram.com/joellesamantha?igsh=ZnVhZjFjczN0OTdn Josh's Instagram: http://instagram.com/joshscutnik Chapters 00:00 Introduction to Cardio Modalities 02:31 Choosing the Right Cardio for You 05:19 Understanding Heart Rate Zones 08:29 Exercise-Induced Asthma and Cardio 10:56 Getting Started with Cardio 14:24 Outdoor vs. Treadmill Running 17:28 Cardio During Pregnancy 20:05 Adapting Cardio for Injury Recovery 22:51 Breathing Techniques in Cardio 25:29 Balancing Cardio and Strength Training 28:16 Nutrition and Cardio Performance 31:08 Mental Toughness in Running 33:48 Warmups and Injury Prevention 36:22 Running Goals and Progression 39:08 Stroller Running Tips 41:49 Winter Running Considerations 45:25 Body Types and Running 48:26 Building a Running Community 51:13 Final Thoughts and Encouragement

Esports podcast specializing in feeding and Overwatch - episode 277. Today's episode was sponsored by FACEIT! Visit FCE.GG/PlatChat for a Discount ahead of FACEIT Season 6!Support Plat Chat and become a member today!https://www.youtube.com/channel/UC38VAZEq3chAIPf4i2AIq7Q/joinFeaturing Jonathan "Reinforce" Snowden, Kevin "AVRL" Walker, Jack "Jaws" Wright and Connor "Avast" Prince.

Today we're going to look at Psalm 1 and the word pictures that we can draw out of it. https://longhollow.com/theforgottenjesuspodcastshownotes

Micah Parsons has arrived in Green Bay and today was his first day of practice in the Green and Gold. Alex and KJ are back with their delayed reactions to the trade, updates on jersey numbers, rosters, and more. How do the Packers stack up against Detroit? Also previewing the big game on Sunday - Welcome back to the IKE Packers Podcast!Help the show by telling another Packers fan! Other ways to contribute are by leaving a 5-star review on Apple Podcasts and subscribing wherever you get your podcasts.@IKE_Packers on X

Cameron Steele joins us for Chapter 375! Cam has lived every facet of the action sports life — from growing up watching his dad race trucks, to racing motocross in his youth, freeriding, and riding in the early days of Freestyle Motocross. He went on to land a commentating gig, building an incredible career in action sports, from calling some of the biggest X Games moments — like Travis Pastrana's double backflip — to becoming a voice on ESPN and covering legendary off-road events like the Baja 1000. But Cam hasn't just commentated at Baja — he's raced it numerous times on both two and four wheels, and still competes today in his truck, racing through the deserts of Mexico. What makes Cameron stand out is how he carries himself and gives back, channeling the positive energy from off-road racing into sharing the stoke with others, supporting communities, and helping those less fortunate.Cam is a stand-up guy, and we're stoked to finally have him on the podcast — this one was a long time coming. Gypsy Gang! Enjoy the show! — Remember to like, subscribe, and drop a comment below! PRESENTED BY: Monster Energy

We will now further our discussion of Shankerian analysis with linear intervalic progressions, compound melodies, transition between voices, more on the neighbor note and a continued effort to galvanize our understanding of the 3 main layers involved in Shenkerian analysis! 

A plant-based lifestyle is put to the test against early and late-stage cancer