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Listen to the latest in Neuroendocrinology research via the NeuroEndoNow podcast.

NeuroEndoNow.org

  • May 18, 2020 LATEST EPISODE
  • infrequent NEW EPISODES
  • 18m AVG DURATION
  • 37 EPISODES


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Latest episodes from NeuroEndoNow's podcast

#37. 3D Primary Cell Culture: A Novel Preclinical Model For Pancreatic Neuroendocrine Tumors

Play Episode Listen Later May 18, 2020 14:35


Mr Simon April-Monn, PhD student with Prof Perren and Dr Marinoni at the University of Bern, Switzerland, talks with NEN about their recent publication in Neuroendocrinology. Interview by Dr Julie Ann Lough April-Monn S.L., Wiedmer T., Skowronska M., Maire R., Schiavo Lena M., Trippel M., Di Domenico A., Muffatti F., Andreasi V., Capurso G., Doglioni C., Kim-Fuchs C., Gloor B., Zatelli M.C., Partelli S., Falconi M., Perren A., Marinoni I. Neuroendocrinology ePub: 3 April 2020 https://doi.org/10.1159/000507669

#34. Hot flushes and KNDy ('Candy') neurons

Play Episode Listen Later Jul 30, 2019 13:36


Prof Naomi E. Rance, University of Arizona, speaks to NEN at ICN2018 in Toronto, to discusses her body of work on the exciting links between KNDy neurons, menopausal women, and novel approaches to managing hot flushes. Interview by Dr Julie Ann Lough

#35. Corticosteroid action in the brain: the potential of selective receptor modulation

Play Episode Listen Later Jul 30, 2019 9:51


Eva Viho, PhD student at Leiden University Medical Centre, talks to NEN about her recent publication "Corticosteroid action in the brain: the potential of selective receptor modulation." Interview by Dr Julie Ann Lough Viho, E.M.G., Buurstede J.C., Mahfouz A., Koorneef L.L., van Weert L.T.C.M., Houtman R., Hunt H.J., Kroon J., Meijer O.C. (2019) Corticosteroid action in the brain: the potential of selective receptor modulation. Neuroendocrinology.DOI:10.1159/000499659    

36. GnRH deficiency disease, Kallman Syndrome, and Hypogonadotropic Hypogonadism

Play Episode Listen Later Jul 30, 2019 6:22


Dr Anna Cariboni from The University of Milan discusses her work on rare GnRH deficiency disease, Kallman Syndrome, and Hypogonadotropic Hypogonadism, using gene knockout studies.  Interview by Dr Julie Ann Lough Oleari R., Lettieri A., Paganoni A., Zanieri L., Cariboni A. Semaphorin Signaling in GnRH Neurons: From Development to Disease. (2018) Neuroendocrinology. DOI:10.1159/000495916    

#33. JAK2/STAT5 pathway mediates prolactin-induced apoptosis of lactotropes

Play Episode Listen Later Feb 4, 2019 21:47


Dr Jimena Ferraris of the Karolinska Institute and the University of Buenos Aires talks with NEN about her recently published work in Neuroendocrinology on the identification of signal transduction pathways that may play a role in the pathogenesis of prolactinomas. Interview by Dr. Julie Ann Lough de Dios, N., Orrillo, S.J., Irizarri, M., Theas, M., Boutillon, F., Candolfi, M., Seilicovic, A., Goffin, V., Pisera, D., Ferraris, J. (2018). JAK2/STAT5 pathway mediates prolactin-induced apoptosis of lactotropes. Neuroendocrinology, doi: 10.1159/000494975.

#32. Reducing the heat with neurokinin antagonism: a new non-hormonal approach for treating hot flashes

Play Episode Listen Later Dec 4, 2018 12:07


Dr Mike Trower of KaNDy Therapeutics talks with NEN at ICN 2018 Toronto about a novel non-hormone approach to reducing hot flashes in women. Interview by Dr. Julie Ann Lough

#31. Female sexual receptivity depends upon extra-ovarian estradiol synthesis in marmoset monkeys

Play Episode Listen Later Dec 4, 2018 14:22


Marissa Kraynak of the University of Wisconsin-Madison talks with NEN at ICN 2018 Toronto about ovarian and extra-ovarian estradiol and how they contribute to sexual receptivity regulation in the marmoset monkey. Interview by Dr. Julie Ann Lough

#30. Novel orally active somatostatin analogs for the treatment of acromegaly

Play Episode Listen Later Dec 4, 2018 13:30


Dr Stephen Betz of Crinetics Pharmaceuticals talks with NEN at ICN 2018 Toronto about his research on the development of treatments for acromegaly; a condition where a pituitary adenoma causes growth hormone hypersecretion causing gigantism in children and abnormal growths in adults. Interview by Dr. Julie Ann Lough

#29. Programming of cognitive functions by early-life stress. A role for nutrition and neuroinflammation

Play Episode Listen Later Dec 4, 2018 14:59


Dr Aniko Korosi of the University of Amsterdam talks with NEN at ICN 2018 Toronto about the effects of early life stress on metabolism and cognition later in life. Interview by Dr. Julie Ann Lough

#28. The role of 11beta-HSD2 in glucocorticoid programming of affective and cognitive behaviours

Play Episode Listen Later Nov 7, 2018 11:41


Dr Megan Holmes of the University of Edinburgh talks to NEN at ICN 2018 Toronto about early life stress and glucocorticoid signaling and the problems it has on longterm outcomes.   Interview by Dr. Julie Ann Lough

#27. Doyens of NE: Prof Sir Steven Bloom

Play Episode Listen Later Aug 7, 2018 26:25


Prof Sir Steven Bloom, Head of Endocrinology at the Imperial College London discusses his career, life's work, and expectations for the future, in an interview with Prof Ashley Grossman of the University of Oxford and St Barts in London. 

#26. Early life stress and long-term outcomes in quails

Play Episode Listen Later Aug 7, 2018 25:23


David Walker, a Ph.D. student at The University of St Andrews in Scotland discusses his research looking at the impact of early life stress and long-term outcomes in quails. He also explored the impact of the hormonal stress response later in life.  Interview by Dr. Julie Ann Lough Published in: David J. Walker, Cédric Zimmer, Maria Larriva, Susan D. Healy, Karen A. Spencer. Early-life adversity programs long-term cytokine and microglia expression within the HPA axis in female Japanese quail. Journal of Experimental Biology 2019 : jeb.187039 doi: 10.1242/jeb.187039 Walker DJ, Spencer KA. Glucocorticoid programming of neuroimmune function. Gen Comp Endocrinol. 2018;256:80-88.

#25. Doyens of NE: Stafford Lightman

Play Episode Listen Later Aug 7, 2018 27:27


Ep 24. Professor Rebecca Reynolds interviews doyen of neuroendocrinology, Professor Stafford Lightman about his work spanning 30 years in the field.

#24. Doyens of NE: Hal Gainer

Play Episode Listen Later May 14, 2018 39:53


In this episode, Professor Gareth Leng talks with the doyen of neuroendocrinology, Professor Hal Gainer about his work over the last 60 years.

#23. Doyens of NE. Charles Sawyer

Play Episode Listen Later May 3, 2018 20:55


Professor Robert Millar speaks with Professor Ei Terasawa about the life and work of the doyen on neuroendocrinology, Professor Charles (Tom) Sawyer.

#22. Anorexia nervosa & hypothalamic reprogramming in mice

Play Episode Listen Later May 3, 2018 19:57


Dr. Odile Viltart, Associate Professor, Université de Lille, INSERM, CHU Lille, UMR-S1172, JPArc - Jean-Pierre Aubert Research Center Neurosciences and Cancer. "Long-term energy deficit in mice causes long-lasting hypothalamic alterations after recovery."

#21. Obesity in Labradors linked to POMC gene deletion

Play Episode Listen Later May 3, 2018 16:34


Dr. Eleanor Raffen, Wellcome Trust Clinical Research Fellow, University of Cambridge.

#20. MRI Study in Transgender Persons

Play Episode Listen Later May 3, 2018 20:50


Sven Mueller from the Department of Experimental Clinical and Health Psychology, Ghent University, talks to us today about his recent published research: A Structural Magnetic Resonance Imaging Study in Transgender Persons on Cross-Sex Hormone Therapy.

#19. IDO predicts death in NEN

Play Episode Listen Later May 3, 2018 15:46


Prof. Joerg Schefold of the Bern University Hospital, Switzerland talks about his latest publication in Neuroendocrinology - 'Increased activity of the immunoregulatory enzyme Indoleamine-2,3-dioxygenase (IDO) with consecutive tryptophan depletion predicts death in patients with neuroendocrine neoplasia"

#18. mtDNA deletions in adrenals

Play Episode Listen Later May 3, 2018 20:36


Prof. Rudi Wiesner talks with Dr Julie Ann Lough about his recently published research: Catecholamine metabolism induces mitochondrial DNA deletions and leads to severe adrenal degeneration during ageing

#17. Social separation and HPA recovery

Play Episode Listen Later May 3, 2018 13:38


In this episode we hear from first author Jack Taylor about his paper 'Reunion behavior after social separation is associated with enhanced HPA recovery in young marmoset monkeys'. Jack is a doctoral student in the Department of Psychology, University of Nebraska at Omaha.

#16. Mast cell hyperplasia & aldosterone

Play Episode Listen Later May 3, 2018 12:30


In this Episode we hear from senior author Hervé Lefebvre discuss his recent paper 'Mast cell hyperplasia is associated with aldosterone hypersecretion in a subset of aldosterone-producing adenomas.'

#15. Hypothalamic apelin/ROS & hepatic glucose metabolism

Play Episode Listen Later May 3, 2018 15:24


In the latest episode of NeuroEndoNow we here from first author Anne Drougard on her paper 'Hypothalamic Apelin/Reactive Oxygen Species Signaling Controls Hepatic Glucose Metabolism in the Onset of Diabetes'.

#14. Feotal impacts from maternal exposure to biosolids

Play Episode Listen Later May 3, 2018 21:54


Dr. Michelle Bellingham, University of Glasgow's Institute of Biodiversity, Animal Health and Comparative Medicine. "Feotal impacts following pre and post conception maternal exposure to Biosolids."

#13. Leptin’s and Taste Bud Calcium Responses

Play Episode Listen Later Apr 28, 2018 8:55


In this episode of NeuroEndoNow first author Tricia Meredith discusses her paper 'Leptin’s Effect on Taste Bud Calcium Responses and Transmitter Secretion'.

#12. Voluntary exercise adapts the HPT Axis in Male Rats

Play Episode Listen Later Apr 27, 2018 22:08


In this podcast Patricia Joseph-Bravo talks to us about the effects of voluntary exercise on the hypothalamus-pituitary-thyroid axis in rats.

Ep 11. Acromegaly: Depression and Anxiety

Play Episode Listen Later Apr 27, 2018 23:07


In this episode of NeuroEndoNow we hear from Victor Geraedts about his latest paper on Health Outcomes in Acromegaly: Depression and Anxiety are Promising Targets for Improving Reduced Quality of Life.

#10. Androgen and Circadian Timing

Play Episode Listen Later Apr 27, 2018 21:42


In this episode Dr Michael Sellix discusses his recent paper Developmental programming by androgen affects the circadian timing system in female mice.

#9. Nitric Oxide Synthase, Estrogen and Energy Homeostasis

Play Episode Listen Later Apr 27, 2018 23:43


In this episode Dr Wagner talks to us about his recent paper 'Role of neuronal nitric oxide synthase in the estrogenic attenuation of cannabinoid-induced changes in energy homeostasis' and highlights the need for gender specific therapies for metabolic disorders.

#8. Diet-induced Hyperleptinemia and Ghrelin Resistance

Play Episode Listen Later Apr 27, 2018 24:10


In this episode of NeuroEndoNow Dr Zane Adrews talks about his work on diet-induced hyopleptinemia and in particualr his paper on 'Evidence that diet-induced hyperleptinemia, but not hypothalamic gliosis, causes ghrelin resistance in NPY/AgRP neurons of male mice' published in Neuroendocrinology.

#7. Doyens of NE: Ernst Knobil

Play Episode Listen Later Apr 27, 2018 27:29


In this latest episode of NeuroEndoNow Professor Tony Plant, University of Pittsburgh, discusses the life and work of Professor Ernst Knobil. Ernst has often been credited as the Father of Neuroendocrinology and here Tony recounts the work of this eminent scientist as well as the man behind the discoveries.

#6. Masterclass Series in Neuroendocrinology

Play Episode Listen Later Apr 26, 2018 25:23


In this latest episode Dr Bill Armstrong and Dr Jeff Tasker talk about the first instalment of the Masterclass series in Neuroendocrinology, Neurophysiology of Neuroendocrine Neurons.

#5. HSP90 Inhibitor Restores Glucocorticoid sensitivity

Play Episode Listen Later Apr 26, 2018 15:02


In this podcast Dr Marcelo Paez-Pereda talks about his recent paper 'A C-terminal HSP90 inhibitor restores glucocorticoid sensitivity and relieves a mouse allograft model of Cushing disease.' published in Nature Medicine, February 2015.

#4. Acyl-ghrelin's effect on neurogenesis & pattern separation

Play Episode Listen Later Apr 26, 2018 11:28


In this Episode first Author Brianne Kent speaks to us about her recent paper 'The orexigenic hormone acyl-ghrelin increases adult hippocampal neurogenesis and enhances pattern separation' published in Psychoneuroendocrinology.

#3. Doyens of NE: Don McCann

Play Episode Listen Later Apr 26, 2018 29:42


In this episode Professor Robert Millar, Editor-in-Chief of Neuroendocrinology talks with Dr Sergio Ojeda about Don McCann, one of the Doyens of Neuroendocrinology. Dr Sergio Ojeda did his postdoctoral training in the lab of Don McCann and is now a Scientist at the Oregon National Primate Research Center.

#2. Regulation of Growth Hormone by NPY

Play Episode Listen Later Apr 26, 2018 19:27


In this podcast we talk with Professor Chen and Dr Steyn on their recent work 'Actions of NPY, and Its Y1 and Y2 Receptors on Pulsatile Growth Hormone Secretion during the Fed and Fasted State' recently published in the Journal of Neuroscience.

#1. Welcome To NeuroEndoNow

Play Episode Listen Later Apr 26, 2018 6:51


In this first episode of the NeuroEndoNow podcast we are joined by Professor Robert Millar, Editor in Chief of Neuroendocrinology and Dr Nick Oswald Founder of Science Squared, who talk to us about the vision behind NeuroEndoNow.

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