Podcasts about Endocrinology

HEALTH NEWS   Wild Blueberries May Benefit the Heart, Metabolism, and Microbiome Nitrate in drinking water linked to increased dementia risk while nitrate from vegetables is linked to a lower risk, researchers find   Afternoon naps clear up the brain and improve learning ability Screen time may increase body fat in children Simple dietary change may slow liver cancer in at-risk patients Wild Blueberries May Benefit the Heart, Metabolism, and Microbiome University of Maine & Florida State University, January 28, 2026 (SciTech Daily) A newly published scientific review brings together a growing body of research on how wild blueberries may influence cardiometabolic health. This area of health includes measures such as blood vessel function, blood pressure, blood lipids (cholesterol and triglycerides), and blood sugar (glucose). The review was developed following an expert symposium. Twelve specialists took part, representing fields that included nutrition, food science, dietetics, nutrition metabolism and physiology, cardiovascular and cognitive health, gut health and microbiology, and preclinical and clinical research models.  The paper evaluates findings from 12 human clinical trials conducted over 24 years across four countries that examined the cardiometabolic effects of wild blueberries. Across the clinical research examined, improvements in blood vessel function stand out as one of the most reliable findings. Studies included in the review suggest that wild blueberries may support endothelial function (or how well blood vessels relax and respond to stimuli). Some trials reported effects within hours of a single serving, while others observed benefits after consistent intake over weeks or months. In one six-week clinical study highlighted in the review, adults who consumed 25 grams of freeze-dried wild blueberry powder each day showed increases in beneficial Bifidobacterium species. The authors identify the gut microbiome as a likely contributor to the cardiometabolic effects linked to wild blueberries. The review also suggests wild blueberry intake may support certain aspects of cognitive performance. Improvements were observed in measures such as thinking speed and memory. Several of the reviewed studies reported clinically meaningful improvements in blood pressure, blood sugar regulation, and lipid markers, including total cholesterol, LDL cholesterol, and triglycerides, after weeks of wild blueberry consumption.   Nitrate in drinking water linked to increased dementia risk while nitrate from vegetables is linked to a lower risk, researchers find   Edith Cowan University (Australia) &  Danish Cancer Research Institute, January 28 2026 (Eurekalert) New research from Edith Cowan University (ECU) and the Danish Cancer Research Institute (DCRI) investigated the association between the intake of nitrate and nitrite from a wide range of different sources, and the associated risk of dementia.  The research, which investigated the association between source-specific nitrate and nitrite intake and incident and early-onset dementia, followed more than 54,000 Danish adults for up to 27 years and found that the source of nitrate was of critical importance in a diet.  The researchers found that people who ate more nitrate from vegetables had a lower risk of developing dementia, while those who consumed more nitrate and nitrite from animal foods, processed meats, and drinking water, had a higher risk of dementia.  When we eat nitrate-rich vegetables, we are also eating vitamins and antioxidants which are thought to help nitrate form the beneficial compound, nitric oxide, while blocking it from forming N-nitrosamines which are carcinogenic and potentially damaging to the brain.  Unlike vegetables, animal-based foods don't contain these antioxidants. In addition, meat also contains compounds such as heme iron which may actually increase the formation of N-nitrosamines. This is why nitrate from different sources may have opposite effects on brain health.   This is the first time that nitrate from drinking water has been linked to higher risks of dementia. The study found that participants exposed to drinking-water nitrate at levels below the current regulatory limits, had a higher rate of dementia.   Water doesn't contain antioxidants that can block formation of N-nitrosamines. Without these protective compounds, nitrate in drinking water may form N-nitrosamines in the body.   Afternoon naps clear up the brain and improve learning ability University of Freiburg (Germany) & University of Geneva, January 28 2026 (Eurekalert) Even a short afternoon nap can help the brain recover and improve its ability to learn. In a study published  in the journal NeuroImage, researchers at the  University of Freiburg and the University of Geneva show that even a nap is enough to reorganize connections between nerve cells so that new information can be stored more effectively.  The new study shows that a short sleep period can relieve the brain and put it back into a state of readiness to learn – a process that could be particularly beneficial for situations with high work load. The study examined 20 healthy young adults who either took a nap or stayed awake on two afternoons. The afternoon nap lasted on average 45 minutes.  The results showed that after the nap, the overall strength of synaptic connections in the brain was reduced – a sign of the restorative effect of sleep. At the same time, the brain's ability to form new connections was significantly improved. The brain was therefore better prepared for learning new content than after an equally long period of wakefulness. Screen time may increase body fat in children Ningbo University (China), January 15 2026 (News-Medical) A study published in Frontiers in Endocrinology reveals that higher screen time is associated with higher levels of body fat accumulation and less favorable obesity-related metabolic indicators in school-aged children, and that cardiorespiratory fitness can significantly influence this association. The study included a total of 1,286 third-grade students from six schools in Ningbo. Participants' cardiorespiratory fitness was assessed using the 20-meter shuttle run test. Information on screen time, physical activity, and diet quality was obtained from self-reported questionnaires. The study analysis indicated that higher screen time is significantly associated with increased visceral fat accumulation, body fat mass index, and body fat percentage, and with lower cardiorespiratory fitness and slightly lower blood levels of HDL-C. The study found that participants with more than two hours of daily screen time exhibit significantly increased visceral fat, fat mass index, and fat percentage, and significantly reduced cardiorespiratory fitness compared to those with less than two hours of daily screen time. Simple dietary change may slow liver cancer in at-risk patients Rutgers University, January 29 2026 (Medical Xpress) People with compromised liver function may be able to reduce their risk of liver cancer or slow its progression with a simple dietary change: eating less protein. A Rutgers-led study has found that low-protein diets slowed liver tumor growth and cancer death in mice, uncovering a mechanism by which a liver's impaired waste-handling machinery can inadvertently fuel cancer. When people consume protein, the nitrogen can be converted into ammonia, a substance that's toxic to the body and brain. A healthy liver typically processes this ammonia into harmless urea, which is excreted via urine. The clinical observation that the liver's ammonia-handling machinery is usually impaired in liver cancer patients is decades old. Zong's team utilized a technique to induce liver tumors in mice without crippling the ammonia-disposal system. The researchers then used gene-editing tools to disable ammonia-processing enzymes in some—but not all. The results were striking: Mice with disabled enzymes and higher ammonia levels developed heavier tumor burdens and experienced a much faster rate of mortality than those with functioning systems. The researchers then tested a straightforward intervention: reducing dietary protein. Mice fed low-protein food exhibited dramatically slower tumor growth and lived significantly longer than those that received food with standard levels of protein BREAK   Introducing the Clips For Today  Sharmine Narwani : The Slow Strangling of Syria and Lebanon - 4:55  Inventing a pandemic - by Maryanne Demasi, PhD - MD REPORTS - full - 2:49    Did Covid mRNA boosters train the immune system to stand down? - full (Maryanne Demasi)  -2:38   Bryce Nickels on X: "-@R_H_Ebright explains why dangerous gain-of-function research should be BANNED https://t.co/2TaLBzzkU0" / X - full (Richard E Bright explains why dangerous gain of function research should be banned)  - 3:17 

If TikTok influencers are to be believed, testosterone, or T, is the answer to everything from fitness frustrations and fatigue to low libido. But doctors are warning that social media misinformation is driving men to seek testosterone therapy that they don't need. This in turn comes with risks for health and fertility. In part one of a miniseries exploring the popularity of testosterone, Madeleine Finlay hears from Prof Channa Jayasena of Imperial College London, who is chair of the Society for Endocrinology, about how this craze is manifesting in NHS clinics, and from ‘Sam' who tells Madeleine about his own journey with the hormone. Help support our independent journalism at theguardian.com/sciencepod

In this episode, Dr. Jacques Jospitre takes us on a journey through the innovative landscape of mental health care, focusing on the integration of technology at SohoMD. Explore how functional medicine and telehealth are breaking barriers in psychiatry, and learn about the crucial roles of nutrition and endocrinology in mental well-being. Dr. Jospitre emphasizes a holistic approach, merging traditional practices with modern technology to enhance mental health outcomes. Chapters: 00:00:00 Introduction to Dr. Jospitre and Soho MD 00:03:00 The Role of Telehealth in Psychiatry 00:09:00 Integrating Functional Medicine 00:15:00 The Impact of Nutrition and Endocrinology 00:21:00 Talk Therapy and the Power of Belief 00:27:00 Social Media's Influence on Mental Health 00:33:00 Scaling Healthcare with Quality Control 00:39:00 The Future of Holistic Mental Health Care Top Insights: Telehealth removes barriers to accessing mental health care. Functional medicine offers a holistic approach to psychiatry. Nutrition and endocrinology are crucial for mental health. Talk therapy is powerful in shaping beliefs and experiences. The placebo effect highlights the power of belief in treatment. Social media impacts mental health, especially in youth. Quality control is vital when scaling healthcare services. Wearable technology provides valuable data for patient care. Holistic mental health care includes relationships and activity levels. Optimizing mental health requires a comprehensive care team. Join us for this insightful discussion and discover how these advancements are shaping the future of mental health care! Connect with Dr. Jacques Jospitre Wefunder: https://wefunder.com/sohomd LinkedIn: https://www.linkedin.com/in/jospitre/ Website: https://www.sohomd.com/

Diabetes often develops silently, and by the time symptoms appear, it may have already been there for years. In this episode of Baptist HealthTalk, host Johanna Gomez sits down with Dr. Pascual DeSantis, Chief of Endocrinology, and Dr. Paolo Carvalho, Geriatric and Family Medicine Physician at Baptist Health, to break down what diabetes really is and why so many people miss the early warning signs. The experts explain the differences between type 1, type 2, and pre-diabetes, common symptoms people brush off, and how lifestyle, genetics, and age all play a role. They also discuss what's happening inside the body, why follow-up care matters, and how uncontrolled blood sugar can affect the heart, kidneys, nerves, and vision. Watch now to learn what signs to look for—and when it's time to talk to your doctor.Host:Johanna GomezAward-Winning Host & JournalistGuests:Pascual De Santis, M.D. Chief of Endocrinology Baptist HealthPaulo Carvalho, M.D.Geriatric Medicine & Family Medicine PhysicianBaptist Health Concierge Medicine 

For some people, diabetes can be very hard to control, even with the standard glucose-lowering therapies. Several studies have demonstrated that endogenous hypercortisolism is prevalent among these individuals. What’s the relationship between type 2 diabetes and hypercortisolism, and what do health care providers need to know about that relationship? To help answer those questions, host Aaron Lohr talks with two guests. Vivian A. Fonseca, MD, is a professor of medicine, assistant dean for clinical research, the Tullis-Tulane Alumni Chair in Diabetes, and chief of the section of endocrinology at Tulane University Medical Center in New Orleans. James W. Findling, MD, is a professor of medicine and surgery at the Medical College of Wisconsin. Drs. Fonseca and Findling are authors of an article published in the journal Diabetes Care looking at the CATALYST study: “Inadequately Controlled Type 2 Diabetes and Hypercortisolism: Improved Glycemia With Mifepristone Treatment.” This episode is made possible by support from Corcept Therapeutics Inc. Show notes are available at https://www.endocrine.org/podcast/enp110 — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

Dr. Rachel Shell, Riverside Endocrinologist, and Nicole Potts, Registered Dietitian, join us to discuss the Weigh to Healthy Living program, and how it can help participants develop and maintain healthy habits to reach weight management and wellness goals.  Learn more about Rachel Shell, MD 

Host: Darryl S. Chutka, M.D.  Guests: Tamim I. Rajjo, M.D., M.P.H.; Meera Shah, M.B., Ch.B.  The class of medications known as the GLP-1 agonists is very popular with our patients. Although initially indicated for management of diabetes, they're frequently taken for the weight loss they commonly produce. How long should these medications be taken? Is there anything we can do to help maintain the weight loss achieved with these medications? How significant is the loss of muscle mass which can occur as part of the weight lost with these medications and can this be minimized. Finally, how safe are the compounded and unapproved versions of these medications patients often find more affordable? These are a few of the questions we'll address in podcast on the GLP-1 medications used for weight loss and we'll tackle the “Controversies and Future of the GLP-1 Medications”. My guests include Dr. Meera Shah and Dr. Tamim Rajjo, both from the Division of Endocrinology at the Mayo Clinic.  Rx for Weight Loss: A Closer Look Series | Mayo Clinic School of Continuous Professional Development  Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts 

In this episode of Health Matters, host Courtney Allison is joined by Dr. Rekha Kumar, endocrinologist and primary care physician at NewYork-Presbyterian and Weill Cornell Medicine, to unpack the science behind aging well. They discuss biohacking, longevity, and health span, separating evidence-based strategies from social media hype and exploring what truly helps us age well.What You'll Learn in This EpisodeWhat “biohacking” really means● How biohacking ranges from simple lifestyle optimization to high-tech, experimental interventions● The difference between lifespan (how long you live) and health span (how long you live well)The Longevity Pyramid● Why the foundation of healthy aging is built on:SleepMovement and strength trainingNutritionStress managementSocial connection● How advanced tools and supplements sit at the top—and why they should never replace the basicsWearables and Tracking● How devices like smartwatches, glucose monitors, and fitness trackers can support behavior change● When tracking becomes counterproductive or stressfulPeptides and “Anti-Aging” Supplements● What's proven (e.g., metformin, GLP-1 receptor agonists)● What's still experimental or under-studied (BPC-157, sermorelin, NAD boosters)Nootropics and Cognitive Enhancers● Everyday nootropics like caffeine● The role of L-theanine for “calm focus”● Myths around perfectly timed caffeine and cortisol rhythmsNutrigenomics and Personalized Nutrition● How genes can influence responses to foods (e.g., lactose intolerance, APOE and saturated fat)● Why many direct-to-consumer genetic tests may overpromiseThe Gut Microbiome● The role of Akkermansia muciniphila in metabolic health● How medications like metformin and GLP-1s may positively shift gut bacteria● What's still unknown about probiotic supplementationGenetic and Biomarker Testing● The difference between actionable medical insights and “information overload”● Why results of unknown significance can cause unnecessary anxietyThe Big Takeaways● There are no true shortcuts to longevity● Sustainable habits beat quick fixes● Our biology is built for rhythms, not constant optimizationFeatured ExpertAbout Rekha B. Kumar, M.D., M.S.Dr. Rekha B. Kumar is an attending endocrinologist at NewYork-Presbyterian/Weill Cornell Medical Center and an associate professor of Clinical Medicine at Weill Cornell Medicine. She specializes in adult primary care and endocrinology and has academic expertise in the diagnosis and treatment of various endocrine disorders, including obesity/weight management, type 2 diabetes, polycystic ovarian syndrome (PCOS), thyroid disorders, as well as metabolic bone disease.Dr. Kumar completed her undergraduate studies at Duke University and received her masters degree in Physiology from Georgetown University. She received her M.D. from New York Medical College and completed her residency training in Internal Medicine at NewYork-Presbyterian/Weill Cornell Medical Center. Dr. Kumar obtained her clinical fellowship in the combined Diabetes, Endocrinology, and Metabolism program at the NewYork-Presbyterian/Weill Cornell Medical Center and the Memorial Sloan Kettering Cancer Center. Dr. Kumar is Board Certified in Internal Medicine, Endocrinology, Diabetes, & Metabolism, and Obesity Medicine.Coming Up NextIn the next episode of Health Matters, we'll explore brain health and the short- and long-term effects of alcohol on the brain with Dr. Hugh Cahill. Subscribe and follow Health Matters on Apple Podcasts, Spotify, or wherever you listen to stay up to date with expert-driven conversations on living well at every stage of life.About Health MattersHealth Matters is your bi-weekly dose of health and wellness information, from the leading experts. Join host Courtney Allison to get news you can use in your own life. New episodes drop each Wednesday.If you are looking for practical health tips and trustworthy information from world-class doctors and medical experts you will enjoy listening to Health Matters. Health Matters was created to share stories of science, care, and wellness that are happening every day at NewYork-Presbyterian, one of the nation's most comprehensive, integrated academic healthcare systems. In keeping with NewYork-Presbyterian's long legacy of medical breakthroughs and innovation, Health Matters features the latest news, insights, and health tips from our trusted experts; inspiring first-hand accounts from patients and caregivers; and updates on the latest research and innovations in patient care, all in collaboration with our renowned medical schools, Columbia and Weill Cornell Medicine.To learn more visit: https://healthmatters.nyp.org

This is the second of two repeated podcasts that were aired a while ago, which are being re-released. This one with Dr Robert Lustig  was particularly popular with listeners. Dr Robert Lustig  argues sugar is fuelling an epidemic of chronic and metabolic disease, from diabetes and strokes, to cancer and heart disease costing hundreds of thousands of lives. He says in a view that some have seen as controversial that we need to see sugar not just as empty calories,  but as a chronic, addictive toxin. In this podcast, Rob reveals just what sugar does to our bodies. And he claims that while modern medicine has been highly effective in treating acute illness, it has failed in its treatment of chronic conditions, only able to treat the symptoms rather than curing the diseases. In his words: “You can't fix healthcare until you fix health. You can't fix health until you fix diet. And, you can't fix diet until you know what the hell is wrong”. Rob explains what he thinks it is essential to eat to stay healthy  and contends that  prevention is not just better than cure it is the cure.   Dr Robert Lustig is a Professor emeritus of Pediatrics, at the Division of Endocrinology at the University of California, San Francisco. He has written a number of best selling books about the dangers of sugar, refined carbohydrates  and metabolic illness. And his research and clinical practice have focussed on childhood obesity and diabetes. If you would like to support this podcast you can do so via Patreon at or via PayPal. The host of the podcast, Liz Tucker is an award winning medical journalist and former BBC producer and director.  You can follow Liz on X and read further information about the podcast on her Substack newsletter. Medical Matters with Liz Tucker has been selected by Feedspot as one of the top 15 UK Medical Podcasts https://blog.feedspot.com/uk_medical_podcasts/

The endocrine system consists of eight major organs that produce and regulate hormones, the chemical messengers that keep the body in balance. Hormones quietly orchestrate everything from our energy and metabolism to mood, sleep, and resilience, acting as an internal communication network that responds to stress, environment, and lifestyle. From cold plunges and saunas to endocrine-disrupting chemicals, even small daily inputs are said to shift this delicate signaling. How does stress really affect our bodies? Does “adrenal fatigue” exist? Is it actually possible to “biohack” our hormones?In this episode, we are joined by Dr. Priya Jaisinghani, MD, ABIM, DABOM, a triple board-certified Endocrinology, Obesity Medicine, and Internal Medicine physician from New York City.Dr. Jaisinghani received her MD from Rutgers/Robert Wood Johnson Medical School, where she also completed her Internal Medicine Residency, Endocrinology and Obesity Medicine Fellowships at Weill Cornell Medicine. Currently, Dr. Jaisinghani is a Diabetes, Metabolism, and Obesity Medicine attending physician at NYU Langone Health, Clinical Assistant Professor of Medicine at NYU Grossman School of Medicine, and a Medical Unit Contributor at ABC News.Dr. Jaisinghani has been featured on CNN, Rolling Stone, The New York Times, The Wall Street Journal, Men's Health, FOX 5 News, and Medscape,Follow Friends of Franz Podcast: Website, Instagram, FacebookFollow Christian Franz (Host): Instagram, YouTube

Drs Kaniksha Desai and Ralph Tufano discuss nanosecond pulsed field ablation technique. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/index/list_15483_0 Kaniksha Desai, MD, Associate Professor of Medicine, Department of Endocrinology, Stanford School of Medicine, Palo Alto, California Ralph P. Tufano, MD, MBA, Clinical Professor, Department of Otolaryngology-Head and Neck Surgery, Florida State University College of Medicine, Sarasota Memorial Health Care System, Sarasota, Florida

Host: Darryl S. Chutka, M.D. Guests: Tamim I. Rajjo, M.D., M.P.H.; Meera Shah, M.B., Ch.B. Using GLP-1 medications for weight loss has become extremely popular. Is this the latest fad in losing weight, or will these medications completely change our approach to managing obesity? They do appear to be very effective in promoting substantial weight loss. What is the history of these medications? Are there differences in the various GLP-1 medications available? What are the potential adverse effects of this drug class? This podcast is the first in a series of three on the GLP-1 medications prescribed for weight loss. The topic for this podcast is “Who Is a candidate for a GLP-1 Medication?” and my guests include Dr. Meera Shah and Dr. Tamim Rajjo, both from the Division of Endocrinology and Metabolism at the Mayo Clinic. Check out the series! Rx for Weight Loss: A Closer Look Series | Mayo Clinic School of Continuous Professional Development Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts 

In recent years, we have seen tremendous growth not just in the popularity of anti-obesity medications, but also in the medications themselves, how effective they are, how many there are. What exactly has changed during this rapid evolution? How safe and effective are these medications today? What challenges still exist in using them? To help answer these questions, host Aaron Lohr speaks with Gitanjali Srivastava, MD, professor of medicine, medical director of Vanderbilt Obesity Medicine, and founding program director of the Obesity Medicine Fellowship at Vanderbilt University Medical Center. Dr. Srivastava presented at the Endocrine Society’s Obesity Fellows Conference in September 2025. The title of her presentation was “Pharmacological Approaches to Treating and Understanding Complicated Obesity.” Listening to this episode can earn you 0.5 ABIM MOC points and 0.5 AMA PRA Category 1 credits. If you are interested in those points and credits, you will need to take a pre-test on the Endocrine Society Center for Learning before listening to this episode. You can find a link in this episode’s show notes. After that pre-test, listen to this episode in the Center for Learning, then take the post-test. This episode is made possible by educational grants from Lilly and Novo Nordisk. Show notes are available at https://www.endocrine.org/podcast/enp109 — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

Rachel Sachs is a professor of law at Washington University in St. Louis. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. S.B. Dusetzina and R.E. Sachs. Insurance Coverage and Pricing of Weight-Loss Drugs in the United States. N Engl J Med 2026;394:105-107. S. Gondi, A.S. Kesselheim, and B.N. Rome. Generic Liraglutide — Overlooked but Not Forgotten. N Engl J Med. DOI: 10.1056/NEJMp2515668.

In this episode of the Evolving Wellness Podcast, I delve into the complexities of vitamin D and melatonin, particularly during the winter months. I discuss the natural decline of vitamin D levels in winter, the critical role of melatonin, and how modern lifestyles disrupt these hormonal balances. The conversation covers the impact of stress, alcohol, and blue light on health, the importance of circadian rhythms, and the potential benefits and drawbacks of vitamin D supplementation. Links: Become a substack subscriber & get early access to podcasts + free courses - https://open.substack.com/pub/sarahkleinerwellness/p/uvbred-light-protocol?r=5eztl9&utm_campaign=post&utm_medium=web&showWelcomeOnShare=trueHoliday Sale - https://www.sarahkleinerwellness.com/SKW-holidayFree Webinar - https://www.sarahkleinerwellness.com/mycircadianapp-free-webinarTimestamps:00:00 Introduction to Vitamin D and Melatonin02:47 Understanding Seasonal Changes in Vitamin D Levels06:13 The Role of Melatonin in Winter Health09:00 Impact of Modern Lifestyle on Vitamin D and Melatonin11:51 The Effects of Stress and Alcohol on Hormonal Balance15:08 Circadian Rhythms and Their Importance17:51 The Dangers of Blue Light and Sleep Disruption21:07 Winter Infections and Their Impact on Vitamin D23:59 Pros and Cons of Vitamin D Supplementation27:13 Understanding Individual Variability in Vitamin D Metabolism29:52 Short-Term Vitamin D Supplementation: When Is It Appropriate?33:14 The Importance of Comprehensive Testing and Monitoring36:01 Conclusion and Future DirectionsReferences & further reading:Article: You've been warned about sunlight but not about supplements - http://sarahkleinerwellness.com/blog/you-ve-been-warned-about-sunlight-but-not-supplementsArticle - Can vitamin D supplements lower your melatonin? https://sarahkleinerwellness.substack.com/p/can-vitamin-d-supplements-lower-yourManson et al. VITAL primary outcomes. N Engl J Med. 2019. PMID: 30415629Sanders et al. Annual high-dose D ↑ falls/fractures. JAMA. 2010. PMID: 20157135Bischoff-Ferrari et al. Monthly high-dose D ↑ falls. JAMA Intern Med. 2016. PMID: 26747333Jackson et al. WHI Ca+D ↑ kidney stones. N Engl J Med. 2006. PMID: 16481635Slominski et al. Melatonin, mitochondria & skin photobiology. Cell Mol Life Sci. 2020.Hamblin MR. Anti-inflammatory photobiomodulation. AIMS Biophys. 2017.Deng et al. Magnesium, vitamin D status & mortality (NHANES). BMC Med. 2013.Holick et al. Translocation of cutaneous vitamin D₃. Endocrinology. 1994.This video is not medical advice & as a supporter to you and your health journey - I encourage you to monitor your labs and work with a professional!________________________________________Get all my free guides and product recommendations to get started on your journey!https://www.sarahkleinerwellness.com/all-free-resourcesCheck out all my courses to understand how to improve your mitochondrial health & experience long lasting health! (Use code PODCAST to save 10%) - https://www.sarahkleinerwellness.com/coursesSign up for my newsletter to get special offers in the future! -https://sarahkleinerwellness.kit.com/profile?_gl=1*1gs7n29*_gcl_aw*R0NMLjE3NjQwOTIxNjcuQ2owS0NRaUF4SlhKQmhEX0FSSXNBSF9KR2poSEZxTTl0blpDSEl4SjYyRHdpa1FuNGc3QXplVll4NVktSFhmSFZZamEwVDAtcU92YXlfQWFBbHp0RUFMd193Y0I.*_gcl_au*MTgwMTYwMTMxMi4xNzYzMzIwODkyLjYyODE4ODI3NC4xNzY1NTA5NjM3LjE3NjU1MDk2MzY.Free Guide to Building your perfect quantum day (start here) -https://www.sarahkleinerwellness.com/opt-in-9d5f6918-77a8-40d7-bedf-93ca2ec8387fMy free product guide with all product recommendations and discount codes:https://www.canva.com/design/DAF7mlgZpJI/xVyE4tiQFEWJmh_Xwx8Kbw/view?utm_content=DAF7mlgZpJI&utm_campaign=designshare&utm_medium=link2&utm_source=uniquelinks&utlId=h0782b52987

A breakthrough in inflammatory support has arrived in the natural health market. PEA, which stands for palmitoylethanolamide, is a naturally occurring fatty acid derivative made in the body and found in small amounts in foods. Several human studies have demonstrated that PEA has broad- spectrum pain-relieving properties, anti-inflammatory effects, and nerve protection.To help us unpack all the research and studies we have Dr. Stengler joining us today.In addition to authoring 30 books on health and several best-sellers such as “The Natural Physician's Healing Therapies,” “Prescription for Natural Cures,” “Prescription for Drug Alternatives,” and “Outside the Box Cancer Therapies,” Dr. Stengler has been published in several peer-reviewed medical journals such as The International Journal of Family & Community Medicine, Endocrinology & Metabolism International Journal, and Journal of Nutritional Health & Food Engineering.Dr. Stengler's, NMD. The newest book is called, The Holistic Guide to Gut Health. A comprehensive yet accessible approach to healing leaky gut and the many uncomfortable symptoms it causes. Dr Stengler is also the founder of The Stengler Center for Integrative Medicine.Talking Points:Palmitoylethanolamide (PEA), is a naturally occurring fatty acid derivative made in the body and found in small amounts in foods. PEA was first discovered in 1957 by scientists at Merck Sharp & Dohme, who isolated it from egg yolk, peanut meal, and soy lecithin. They found that PEA had anti-inflammatory properties in guinea pigs.However, PEA's role as a potential therapeutic agent was not widely recognized until 1993, when Rita Levi-Montalcini and her colleagues published research that suggested PEA has anti-inflammatory properties. Levi-Montalcini's group termed PEA an autocoid local injury antagonist (ALIA), and suggested that it acts locally to counteract injury.Multiple studies have demonstrated that PEA improves all sorts of pain. For example, a 2023 analysis of 11 studies found that PEA improved pain of various conditions, including muscle and joints, nerves, gynecological, and digestive. In terms of joint pain, a high-quality study demonstrated that PEA significantly reduced adult joint pain compared to placebo. Moreover, 8 clinical trials demonstrated that PEA was effective for low back pain, sciatica, and carpal tunnel syndrome. Even migraine headache pain was shown in published research to be improved with PEA.Lipid mediators help to balance the immune, nervous, and endocrine systems, affecting pain pathways related to inflammation. But unfortunately, due to changing diets, many of us do not get the nutrition and activity we need to make enough PEA ourselves.Supplemental PEA, by Levagen+ is properly formulated for optimal bioavailability, 75% more bioavailable to cell receptors than dietary forms. Levagen+ liposomal delivery of PEA has been clinically studied and shows benefits in joint pain, nerve pain, migraine, infections, sleep, and cognitive function.Learn more about Dr. Mark Stengler, NMDLearn more about Emerald Labs PEA+ Levagen Use the code: Forever and get 20% off your order.

Welcome to the emDOCs.net podcast! Join us as we review our high-yield posts from our website emDOCs.net.Today on the emDOCs cast with Brit Long (@long_brit), we cover metformin toxicity.To continue to make this a worthwhile podcast for you to listen to, we appreciate any feedback and comments you may have for us. Please let us know!Subscribe to the podcast on one of the many platforms below:Apple iTunesSpotifyGoogle Play 

What is a call? How does a person know if God is calling them to mission service? Join in a discussion as these and other questions are addressed.

In the last five years, the field of artificial intelligence and robotics has taken off and has become a part of our everyday life, and it continues to grow and evolve. How are AI and robotics shaping the field of medicine? How is it improving the lives of doctors and patients? We used to ask, “What is the role of AI in medicine?” Are we getting closer to a time where we’ll be asking what the role is of humans? To help us answer these questions, host Aaron Lohr talks with Hassan M. Heshmati, MD. Dr. Heshmati has been a physician for 49 years and an endocrinologist for 45 years, with experience in clinical research and academia and in the pharmaceutical biotech industry. He founded Endocrinology Metabolism Consulting, based in Anthem, Ariz., and presented an abstract at ENDO 2025 titled, “Update on the Use of Robotic Surgery and Artificial Intelligence for Adrenal Tumors.” Show notes are available at https://www.endocrine.org/podcast/enp108 — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

Low resource settings require much innovation and streamlining resources to meet set goals. With healthcare becoming more commercial and profit driven, missional healthcare in low resource settings faces many challenges. Sustainability is a big question with people finance , and equipment scarce and hard to come by. Missional models of healthcare often run into hurdles of sustainability, longevity and relevance even as healthcare slowly turns into business. In this setting of multifactorial challenges and increasing compliances how can missional healthcare be relevant and sustainable? Many saints of God have committed their lives to fulfil this great commission in some of the most underserved and unreached areas of the world. With the birth of Emmanuel Hospital Association (EHA) a different model of missional healthcare emerged in India. Over the last 55 years of its existence, EHA has shown that through all the challenges, this may be one of the ways to sustain missional healthcare in areas of need. With increasing divide between the rich and poor, overwhelmed government systems, a ruthless insurance system, and high end corporate healthcare, it is still possible for missional healthcare to provide low cost, high quality, technologically advanced care to people in need while remaining sustainable. We bring lessons from India and our experience with Emmanuel Hospital Association over the last 3 decades.

Send us a textGrab your trainers, your dog lead, or even shake your jingle bells, and join us for some free CPD as we have another relaxed round up of recent Red Whale primary care Pearls of wisdom.  In the first of two episodes this month, Fi and Nik discuss : Spotting adrenal crisis. Adrenal insufficiency and Addison's disease can be easy to miss. We've recently updated our article on this, so we thought we'd share it as a Pearl, distilling the 2024 NICE guidance for you.Recurrent bacterial vaginosis: time to consider partner treatment? Bacterial vaginosis is the commonest cause of pathological vaginal discharge in women of reproductive age. But it's not an easy diagnosis for us to confirm – although we can suspect it clinically and manage empirically.  We'll give you a refresher on BV infection and diagnosis in primary care and then think about managing recurrent BV, where there's a new development.Listen as soon as you can to ensure you have full access to all the free resources. Further Pearls from November will be covered next time.Useful LinksAdrenal insufficiency and Addison's diseaseFor professionals:The Society of Endocrinology – adrenal crisisFor patients:Addison's Disease Self-help Group (include sections on emergency kits and sick day rules; there doesn't appear to be a patient group for other forms of adrenal insufficiency) GP Trainee Essentials support package information, and the Red Whale CalendarSend us your feedback podcast@redwhale.co.uk or send a voice message Sign up to receive Pearls here. Pearls are available for 3 months from publish date. After this, you can get access them plus 100s more articles when you buy a one-day online course from Red Whale OR sign up to Red Whale Unlimited. Find out more here. Follow us: X, Facebook, Instagram, LinkedInDisclaimer: We make every effort to ensure the information in this podcast is accurate and correct at the date of publication, but it is of necessity of a brief and general nature, and this should not replace your own good clinical judgement, or be regarded as a substitute for taking professional advice in appropriate circumstances. In particular, check drug doses, side-effects and interactions with the British National Formulary. Save insofar as any such liability cannot be excluded at law, we do not accept any liability for loss of any type caused by reliance on the information in this podcast....

Podcast Family, we have covered PCOS on this show many times in the past; and yet- again, there is new information! A new publication from AJOG (Gray journal) describes a new meta-analysis on preconception/continued metformin use in the first trimester. Is this helpful? How does this contrast with the 2023 international guidance update on PCOS? Listen in for details. 1. ASRM: Recommendations from the 2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome (2023)2. Cheshire J, Garg A, Smith P, Devall AJ, Coomarasamy A, Dhillon-Smith RK. Preconception and first-trimester metformin on pregnancy outcomes in women with polycystic ovary syndrome: a systematic review and meta-analysis. Am J Obstet Gynecol. 2025 Dec;233(6):530-547.e8. doi: 10.1016/j.ajog.2025.05.038. Epub 2025 Jun 3. PMID: 40473092.3. Løvvik TS, Carlsen SM, Salvesen Ø, et al. Use of Metformin to Treat Pregnant Women With Polycystic Ovary Syndrome (PregMet2): A Randomised, Double-Blind, Placebo-Controlled Trial. The Lancet. Diabetes & Endocrinology. 2019;7(4):256-266. doi:10.1016/S2213-8587(19)30002-6.4. Teede HJ, Tay CT, Laven J, et al. Recommendations From the 2023 International Evidence-Based Guideline for the Assessment and Management of Polycystic Ovary Syndrome. Fertility and Sterility. 2023;120(4):767-793. doi:10.1016/j.fertnstert.2023.07.025.

Join Dr. Steven Petak, Past President of AACE and ISCD and former Chief of Endocrinology at Houston Methodist Hospital, as he leads an in-depth conversation on Hypophosphatemia with Dr. Laila Tabatabai, Associate Professor of Clinical Medicine at Weill Cornell and metabolic bone specialist at Houston Methodist, and Dr. Basma Abdulhadi, Assistant Professor of Medicine at the University of Alabama at Birmingham and head of bone densitometry. Together, they discuss how to distinguish Hypophosphatemia from osteoporosis and osteomalacia, recognize key symptoms across ages, and apply a focused diagnostic workup. The discussion also highlights FGF23-mediated disorders, XLH, and current treatment approaches including burosumab, reinforcing a key reminder for clinicians to check phosphate levels to help prevent missed diagnoses. This episode is made possible through a sponsorship from Kyowa Kirin.Kyowa Kirin was not involved in the content of the podcast.

On this episode, Isaac Sachmechi, MD, Endocrinology, Diabetes, and Metabolism, Internal Medicine at NYC Health + Hospitals/Queens joins the podcast to discuss why NYC Health + Hospitals/Queens is recognized for excellence in diabetes care. He shares insights into the future of diabetes treatment, highlights advancements in care delivery, and explores strategies for improving patient outcomes in endocrinology.

With updated thyroid cancer guidelines, adjunct diagnostic and treatment tools, and growing interest in minimalist approaches, it is increasingly challenging to know the optimal management for patients with small, differentiated thyroid cancer including when to refrain from operating. In this episode, we discuss the nuanced decision making in managing these patients, the multiple factors that are taken into consideration, and strategies in conducting efficacious conversations with patients. Hear from our world-renowned expert panel, Dr. Michael Tuttle, Professor and Chief of Endocrinology at Memorial Sloan Kettering Cancer Center, and Dr. Douglas Fraker, The Jonathan Rhoads Professor of Surgery Emeritus at the University of Pennsylvania , moderated by Dr. Mahsa Javid, Endowed Chair in Endocrine Surgery.

Drs Kaniksha Desai and Whitney Goldner discuss a new guideline approach for active surveillance for selected patients with low-risk papillary thyroid cancer. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/index/list_15483_0 Kaniksha Desai, MDAssociate Professor of Medicine, Department of Endocrinology, Stanford School of Medicine, Palo , Whitney S. Goldner, MD, Professor; Head, Department of Internal Medicine, Division of Diabetes, Endocrinology, and Metabolism, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, Colorado

We welcome Dr. Pasquale Passarella, an endocrinologist at Albany Med. Ray Graf hosts.

Join Dr. Bahar Force, Endocrinologist, Medical Director of the Pituitary Center, and Associate Program Director of the Endocrinology Fellowship Program at Baylor College of Medicine, as she speaks with leading experts Dr. James Findling, Clinical Professor of Endocrinology at the Medical College of Wisconsin, and Dr. Ty Carroll, Visiting Professor of Endocrinology and Chief of the Division of Endocrinology, Diabetes and Metabolism at the University of Wisconsin Madison, for a clinician-focused conversation on non-neoplastic hypercortisolism. Together, they discuss how common conditions can lead to cortisol elevations that resemble Cushing syndrome, the clinical patterns that raise concern for neoplastic hypercortisolism, and the growing role of the Desmopressin Stimulation Test in helping distinguish between the two. The episode also highlights emerging research, including insights from the Catalyst study and the potential role of cortisol-directed therapy. 

Technically known as glucagon-like peptide-1 receptor agonists, or GLP-1, these drugs have been around for years for treating diabetes. Now it seems most people think of GLP-1 drugs as medications to lose weight, and these medications are so popular that for a time, supply could not meet demand, leaving many to seek compounded GLP-1 medications, which were more accessible and affordable. However, compounded medications are not FDA-approved, and there are questions regarding their safety and efficacy. What do doctors and patients need to know when considering using compounded obesity medications? To help answer this, host Aaron Lohr talks with Michael Weintraub, MD, an endocrinologist at NYU Langone Division of Endocrinology. Dr. Weintraub serves on the exam writing committee for the American Board of Obesity Medicine. Support for this episode was provided by Lilly. Show notes are available at https://www.endocrine.org/podcast/enp107 — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

In this episode of the RCP Medicine Podcast, Dr Sagen Zac-Varghese, Consultant in Diabetes and Endocrinology, East and North Herts Teaching NHS Trust is joined by Dr Samantha Scholtz , Consultant Psychiatrist, Imperial Weight Centre, St Mary's Hospital to explore the complex relationship between obesity and mental health. Drawing on clinical experience and recent research, they discuss the stigma surrounding obesity, its psychological impact, and how healthcare professionals can better support patients. The conversation covers the physiological drivers of weight regain,  and the evolving role of bariatric surgery and GLP-1 agonists in treatment. Dr Scholtz  also shares practical advice on screening for mental health disorders, managing eating behaviours, and navigating sensitive conversations in clinical settings.ResourcesRCP elearning - ObesityBinge eating disorder: https://www.beateatingdisorders.org.uk/https://www.rcpsych.ac.uk/mental-health/mental-illnesses-and-mental-health-problems/binge-eating-disorderhttps://www.nationaleatingdisorders.org/feast-resources/Weight stigma:https://www.worldobesity.org/what-we-do/our-policy-priorities/weight-stigmaRCP Links Education Events Membership Improving care Policy and campaigns RCP Social Media Instagram LinkedIn Facebook X Bluesky Music: Episode 50 onward - Bensound.com Episodes 1 - 49 'Impressive Deals' - Nicolai Heidlas

Drs Kaniksha Desai and Mimi Hu discuss RET inhibitors for advanced medullary thyroid cancer on the Thyroid Stimulating Podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/index/list_15483_0 Kaniksha Desai, MD, Associate Professor of Medicine, Department of Endocrinology, Stanford School of Medicine, Palo Alto, California Mimi I. Hu, MD, Professor, Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas MD Anderson Cancer Center, Houston, Texas

ABOUT THIS EPISODE Carcinoid syndrome can be confusing and often difficult to diagnose. In this episode, Dr. Joseph Dillon, Endocrinologist and Director of the University of Iowa Neuroendocrine Multidisciplinary Tumor Clinic, explains what carcinoid syndrome is, how it's diagnosed, and the various ways it can be treated. He highlights key symptoms, testing, and treatment approaches—including somatostatin analogs and telotristat—and discusses how to distinguish carcinoid syndrome from other causes of diarrhea and flushing.In the second half of the episode, Dr. Dillon shares insights from his separate line of research on GLP-1 receptor agonist weight-loss drugs (such as Ozempic® and Mounjaro®) and their potential implications for neuroendocrine tumor patients. (Note: this topic is unrelated to carcinoid syndrome.)TOP TEN QUESTIONS What is carcinoid syndrome? Who is affected by carcinoid syndrome? How does someone know if they have carcinoid syndrome? What are the tests for carcinoid syndrome? How is carcinoid syndrome distinguished from other causes of my symptoms? *Could the tests be negative, but someone can still have carcinoid syndrome?Can someone have no evidence of neuroendocrine tumors and still have carcinoid syndrome?For those who have carcinoid syndrome, what additional tests should they have?Why should carcinoid syndrome be treated? What are the possible issues if it is not treated?How is carcinoid syndrome treated? *What is on the horizon for carcinoid syndrome treatment?Can carcinoid syndrome be prevented or detected early? Is there anything people can do to prevent or lessen carcinoid syndrome symptoms? Are there any factors that worsen carcinoid syndrome, such as age, weight or other diseases? You recently published a study discussing the possible risks of using certain weight loss drugs in people with neuroendocrine cancer. Could you tell us more about this study? What was the drug, and what did you find? What does it mean? What do you want the NET patient community to understand about your recent findings?ABOUT DR. JOSEPH DILLON Dr. Dillon is a Professor of Medicine in the Division of Endocrinology at the University of Iowa Hospitals and Clinics. He directs the University of Iowa Neuroendocrine Multidisciplinary Tumor Clinic. This was the first and only US NET Clinic to be recognized as a Center of Excellence by the European NET Society. He is also the Director of the PheoPara Alliance Center of Excellence at University of Iowa.  His clinical practice is entirely focused on the care of people with neuroendocrine tumors, both carcinoid type and paraganglioma. He has participated in clinical trials and publications related to diagnostic and therapeutic nuclear agents and drug therapies in this population. Prior to focusing on NET he made important discoveries in the field of GLP-1 which are now becoming of importance to NET patients taking popular weight loss drugs.For more information, visit NCF.net/podcast/49For more information, visit NCF.net.

This episode covers early puberty.Written notes can be found at https://zerotofinals.com/paediatrics/development/earlypuberty/Questions can be found at https://members.zerotofinals.com/Books can be found at https://zerotofinals.com/books/The audio in the episode was expertly edited by Harry Watchman.

Many Americans are looking for natural lipid-balancing approaches that do not carry the risk associated with common cholesterol-lowering drugs. Today we will cover Cholesterol Health and the science behind Bergamot.To help us unpack all the research and studies we have Dr. Stengler joining us today.In addition to authoring 30 books on health and several best-sellers such as “The Natural Physician's Healing Therapies,” “Prescription for Natural Cures,” “Prescription for Drug Alternatives,” and “Outside the Box Cancer Therapies,” Dr. Stengler has been published in several peer-reviewed medical journals such as The International Journal of Family & Community Medicine, Endocrinology & Metabolism International Journal, and Journal of Nutritional Health & Food Engineering.Dr. Stengler's, NMD. The newest book is called, The Holistic Guide to Gut Health.A comprehensive yet accessible approach to healing leaky gut and the many uncomfortable symptoms it causes. Dr Stengler is also the founder of The Stengler Center for Integrative Medicine.Learn more about the products offered at Emerald Labs to help support your Heart Health.Cholesterol HealthBergamot+Listeners can save 20% OFF when using the cod: Forever at Emeraldlabs.com 

Send us a message with this link, we would love to hear from you. Standard message rates may apply.We discuss a clear, practical guide to menopause, explaining what it is, why it happens, and how to manage the most common symptoms with everyday steps and evidence-based options. We set up next week's deep dive on hormone therap. • Defining menopause and typical timing• Why estrogen declines and bodywide effects• Common symptoms across sleep, mood, and metabolism• Hot flashes and night sweats frequency and duration• Vaginal and urinary symptoms that mimic UTIs• Bone density loss and changing heart risk• Lifestyle tactics that actually help• When to ask about hormonal and non-hormonal treatments• Teaser for hormone therapy update next weekSend us an email at yourcheckuppod@gmail.comReferences1. Menopause-Biology, Consequences, Supportive Care, and Therapeutic Options. Davis SR, Pinkerton J, Santoro N, Simoncini T. Cell. 2023;186(19):4038-4058. doi:10.1016/j.cell.2023.08.016.2. The Menopause Transition: Signs, Symptoms, and Management Options. Santoro N, Roeca C, Peters BA, Neal-Perry G. The Journal of Clinical Endocrinology and Metabolism. 2021;106(1):1-15. doi:10.1210/clinem/dgaa764.3. Management of Menopausal Symptoms: A Review. Crandall CJ, Mehta JM, Manson JE. JAMA. 2023;329(5):405-420. doi:10.1001/jama.2022.24140.4. Menopause. Davis SR, Lambrinoudaki I, Lumsden M, et al. Nature Reviews. Disease Primers. 2015;1:15004. doi:10.1038/nrdp.2015.4.5. Menopause: Physiology, Definitions, and Symptoms. Gatenby C, Simpson P. Best Practice & Research. Clinical Endocrinology & Metabolism. 2024;38(1):101855. doi:10.1016/j.beem.2023.101855.6. Reproductive Aging in Biological Females: Mechanisms and Immediate Consequences. Muhammad YA. Frontiers in Endocrinology. 2025;16:1658592. doi:10.3389/fendo.2025.1658592.7. Treating Menopause - MHT and Beyond. Davis SR, Baber RJ. Nature Reviews. Endocrinology. 2022;18(8):490-502. doi:10.1038/s41574-022-00685-4.8. Management of Perimenopausal and Menopausal Symptoms. Duralde ER, Sobel TH, Manson JE. BMJ (Clinical Research Ed.). 2023;382:e072612. doi:10.1136/bmj-2022-072612.9. Hormone Therapy for Postmenopausal Women. Pinkerton JV. The New England Journal of Medicine. 2020;382(5):446-455. doi:10.1056/NEJMcp1714787.10. An Empowerment Model for Managing Menopause. Hickey M, LaCroix AZ, Doust J, et al. Lancet (London, England). 2024;403(10430):947-957. doi:10.1016/S0140-6736(23)02799-X.11. Menopause. Carter AE, Merriam S. The Medical Clinics of North America. 2023;107(2):199-212. doi:10.1016/j.mcna.2022.10.003.Support the showSubscribe to Our Newsletter! Production and Content: Edward Delesky, MD & Nicole Aruffo, RNArtwork: Olivia Pawlowski

In this episode, Dr. Andrea Rosen, a first-year endocrinology fellow at UVMMC, opens with a rapid-fire endocrine round, from her favorite organ and go-to hormone excuse to T3 vs. T4, metformin's true identity, and endocrinology in five words. She then shares what inspired her to pursue medicine, the biggest learning curves of her first fellowship year, and the moments that reaffirmed her choice of endocrinology. Dr. Rosen also offers advice for trainees considering the field and reflects on where she hopes to take her career next.   Co-Hosts: Caity Decara: caitlin.decara@med.uvm.edu Haley Bayne: haley.bayne@med.uvm.edu

In this episode of Molecule to Market, your host Raman Sehgal discusses the pharmaceutical and biotechnology supply chain with Jean-François Brepson, Chief Executive Officer at PathoQuest. The conversation covers: Navigating 20 years of global leadership roles at Ipsen before moving from the corporate world into an investor-led entrepreneurial adventure The tough decision to refocus PathoQuest from diagnostics into a pure play CRO and pharma services business How a major strategic partnership transformed the company's trajectory and why Jean sees partnerships as a competitive weapon Riding the tailwind of the FDA's move away from animal testing and offering something game-changing in the CMC and GMP space The opportunities ahead for CROs and CDMOs in helping unlock the next wave of innovation Jean-François Brepson is a dedicated leader with deep experience in biotechnology and pharmaceuticals. Since becoming CEO of PathoQuest in 2015, he has built the company into a leading global CRO specializing in quality control of biological drugs using Next Generation Sequencing (NGS). Over his career, he has advanced innovative technologies and solutions that bridge scientific progress with real-world application. Prior to joining PathoQuest, Jean was Senior Vice President at Ipsen, where he led the global GI-Oncology and Endocrinology franchise.   Molecule to Market is sponsored by Bora Pharma, Charles River, and Lead Candidate. Please subscribe, tell your industry colleagues, and help us celebrate the value of the global life science outsourcing space. We'd also appreciate a positive rating!

Bariatric surgery is a procedure used to manage obesity and obesity-related conditions. While studies have shown that bariatric surgery leads to significant weight loss, are there cases where it may be important to consider reversing the procedure? What would such cases look like? How effectively can bariatric surgery be reversed? To help explore those questions, host Aaron Lohr talks with Katherine Hazen, MD, a second-year endocrine fellow at the University of Rochester Medical Center. She and colleagues presented an abstract at ENDO 2025 titled, “Going Backwards as a Means of Moving Forward: Severe Hypoglycemia After Bariatric Surgery.” Show notes are available at https://www.endocrine.org/podcast/enp106 — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

Send us a message with this link, we would love to hear from you. Standard message rates may apply.We break down osteopenia and osteoporosis with clear steps to protect independence: how bones weaken, how DEXA scoring works, and which daily habits reduce fracture risk. We share nutrition, exercise, lifestyle changes, and home safety that make a measurable difference.• key stats on fracture risk in women and men over 50• definitions of osteopenia and osteoporosis using T-scores• hip, spine and wrist as common fracture sites• why bone loss accelerates after menopause• risk factors including family history, smoking and low weight• DEXA scan basics and when to ask for screening• calcium and vitamin D targets and food sources• Mediterranean diet, protein and supportive micronutrients• weight-bearing, resistance and balance training essentials• Tai Chi and fall risk reduction• home safety changes that prevent falls• when medications like bisphosphonates or denosumab help• practical questions to ask your clinicianReferences1. Osteoporosis: Common Questions and Answers. Harris K, Zagar CA, Lawrence KV. American Family Physician. 2023;107(3):238-246.2. Postmenopausal Osteoporosis. Walker MD, Shane E. The New England Journal of Medicine. 2023;389(21):1979-1991. doi:10.1056/NEJMcp2307353.3. American Association of Clinical Endocrinologists/American College of Endocrinology Clinical Practice Guidelines for the Diagnosis and Treatment of Postmenopausal Osteoporosis-2020 Update. Camacho PM, Petak SM, Binkley N, et al. Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. 2020;26(Suppl 1):1-46. doi:10.4158/GL-2020-0524SUPPL.4. Global, Regional Prevalence, and Risk Factors of Osteoporosis According to the World Health Organization Diagnostic Criteria: A Systematic Review and Meta-Analysis. Xiao PL, Cui AY, Hsu CJ, et al. Osteoporosis International : A Journal Established as Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 2022;33(10):2137-2153. doi:10.1007/s00198-022-06454-3.5. Screening for Osteoporosis to Prevent Fractures: US Preventive Services Task Force Recommendation Statement. Curry SJ, Krist AH, Owens DK, et al. JAMA. 2018;319(24):2521-2531. doi:10.1001/jama.2018.7498.6. The Cost of Osteoporosis, Osteopenia, and Associated Fractures in Australia in 2017. Tatangelo G, Watts J, Lim K, et al. Journal of Bone and Mineral Research : The Official Journal of the American Society for Bone and Mineral Research. 2019;34(4):616-625. doi:10.1002/jbmr.3640.7. The Prevalence and Treatment Rate Trends of Osteoporosis in Postmenopausal Women. Zhang X, Wang Z, Zhang D, et al. PloS One. 2023;18(9):e0290289. doi:10.1371/journal.pone.0290289.8. Osteopenia: A Key Target for Fracture Prevention. Reid IR, McClung MR. The Lancet. Diabetes & Endocrinology. 2024;12(11):856-864. doi:10.1016/S2213-8587(24)00225-0.9. Effectiveness and Safety of Treatments to Prevent Fractures in People With Low Bone Mass or Primary Osteoporosis: A Living Systematic Review and Network Meta-Analysis for the American College of Physicians. Ayers C, Kansagara D, Lazur B, et al. Annals of Internal Medicine. 2023;176(2):182-195. doi:10.7326/M22-0684.Support the showSubscribe to Our Newsletter! Production and Content: Edward Delesky, MD & Nicole Aruffo, RNArtwork: Olivia Pawlowski

What role does thyroid artery embolization play in contemporary thyroid cancer care? Dr. Juan Camacho, an interventional radiologist from Sarasota, Florida, joins host Dr. Sabeen Dhand to discuss how this emerging technique is reshaping the management of thyroid malignancies. --- SYNPOSIS Dr. Camacho shares his experiences establishing a multidisciplinary team at Memorial Sloan Kettering Cancer Center dedicated to the management of thyroid malignancies, highlighting the critical role of collaboration in the successful implementation of this emerging treatment. He details key procedural techniques, emphasizing the importance of recognizing anatomic variations that can influence technical success. He also examines how arterial supply and lesion location inform procedural planning and decision-making, and outlines his technical approach to thyroid artery embolization, including the use of a radial artery access, catheter selection strategies, and the application of cone-beam CT for procedural optimization. Finally, he reviews his pre- and post-procedural management strategies, including the role of beta blockers in optimizing patient outcomes. The discussion concludes with illustrative case studies demonstrating substantial reductions in thyroid volume and symptomatic relief, notably achieved without post-procedural hypothyroidism. --- TIMESTAMPS 00:00 - Introduction03:31 - Pioneering Thyroid Ablation at Sloan Kettering06:53 - The Need for Thyroid Artery Embolization25:08 - Pre-Procedural Planning32:41 - Embolization Technique and Procedure44:48 - Choosing the Right Catheter for the Job45:43 - Ensuring Patient Comfort and Safety47:09 - High-Stakes Imaging and Safety Protocols47:55 - Innovative Techniques and Case Studies51:02 - Post-Procedure Management and Follow-Up56:30 - Engaging with Endocrinology and Surgeons01:00:00 - Case Studies and Practical Applications

Send us a textHow hunger, hormones, and brain wiring make animals switch between parenting and aggression.Episode Summary: Dr. Johannes Kohl explains instinctive behaviors in mice, focusing on how hunger and estrous cycle hormones interact in the hypothalamus to toggle between parental care and pup-directed aggression in virgin females; he also details how pregnancy hormones rewire the medial preoptic area for robust maternal behavior before birth, revealing multi-timescale neural integration of internal states.About the guest: Jonny Kohl, PhD is a group leader at the Francis Crick Institute in London, heading the State-Dependent Neural Processing Lab.Discussion Points:Instincts are pre-wired, robust yet modifiable by experience and states like hunger.AGRP “hunger neurons” in the hypothalamus regulate hunger state and respond to environmental cues related to food.Hunger regulates parental care neurons in medial preoptic area (MPOA) via inhibitory peptides.Estrous cycle (4-5 days) in mice comes with fluctuations in estradiol & progesterone; their ratio, not absolute levels, gates aggression probability.Hormone ratio sensed in MPOA neurons via nuclear receptors altering gene expression of HCN ion channels, changing excitability.Pregnancy (20 days) boosts parental circuits in MPOA via hormone surges before pregnancy ends, enabling instant care at birth.Hormone fluctuations enable adult brain plasticity.Humans disrupt natural cycles (e.g., hormonal contraceptives, GLP-1 drugs) that have broad, poorly understood brain effects.Reference Paper:Study: Integration of hunger and hormonal state gates infant-directed aggressionRelated Episode:M&M 89: Neuroscience of Aggression, Sex, Behavior, Hormones, Emotion & Consciousness | David Anderson*Not medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

La inflamación silenciosa o de bajo grado es uno de los procesos más estudiados de los últimos años, y se ha convertido en la base común de muchas patologías modernas: desde la resistencia a la insulina, el hígado graso o las enfermedades cardiovasculares, hasta trastornos del ánimo, alteraciones digestivas o incluso ciertos tipos de cáncer. En este episodio te explico qué es exactamente esta inflamación crónica, qué la causa y por qué puede pasar desapercibida durante años. Hablaremos del papel del estrés, el sueño, la microbiota, la alimentación y el sedentarismo, y de cómo pequeños cambios en tu estilo de vida pueden reducir los marcadores inflamatorios y mejorar tu salud a largo plazo. Una guía completa para entender qué significa realmente “comer y vivir de forma antiinflamatoria” y por qué este enfoque puede marcar la diferencia entre tener energía o arrastrar cansancio constante, entre salud y enfermedad.

In this episode, Dr. Brendan McCarthy, Chief Medical Officer of Protea Medical Center, dives deep into estrone, one of the three key estrogens, and explains why understanding it is crucial for women's health. Learn about: The differences between estradiol, estriol, and estrone How estrone levels shift during perimenopause and menopause Why oral estrogen can dramatically increase estrone The impact of lifestyle factors like diet, body fat, stress, alcohol, and sedentary behavior on estrogen balance Practical tips to support healthy estrogen metabolism naturally Dr. McCarthy breaks down complex biochemistry in a clear, actionable way so you can take charge of your hormonal health.   Citations: 1. Bulun, Serdar E., et al. “Aromatase and Estrogen Biosynthesis in Adipose Tissue.” Endocrine Reviews, vol. 23, no. 3, 2002, pp. 305–342. 2. Labrie, Fernand, et al. “Importance of the Intracrinology of Estrogen Synthesis in Peripheral Tissues in Postmenopausal Women.” Journal of Steroid Biochemistry and Molecular Biology, vol. 118, nos. 4–5, 2010, pp. 273–279. 3. Sasano, Hironobu, and Toshihiko Harada. “Differential Expression of Aromatase and 17β-Hydroxysteroid Dehydrogenase Isoenzymes in Human Tissues.” Journal of Steroid Biochemistry and Molecular Biology, vol. 86, no. 3–5, 2003, pp. 327–333. 4. Yager, James D., and Nancy E. Davidson. “Estrogen Carcinogenesis in Breast Cancer.” New England Journal of Medicine, vol. 354, no. 3, 2006, pp. 270–282. 5. Cavalieri, Ercole L., and Eleanor G. Rogan. “Depurinating Estrogen-DNA Adducts, Mechanisms of Formation, and Prevention.” Clinical Cancer Research, vol. 16, no. 3, 2010, pp. 596–602. 6. Suba, Zsuzsanna. “Circulating Estrogens and Estrogen Metabolism in Obese Women.” Journal of Clinical Endocrinology and Metabolism, vol. 98, no. 11, 2013, pp. 4336–4344. 7. Simpson, Evan R., and Konstanze C. Pike. “Aromatase Expression in Adipose Tissue: Relationship to Obesity and Insulin Resistance.” Endocrinology, vol. 156, no. 9, 2015, pp. 3422–3435. 8. Key, Timothy J., et al. “Circulating Sex Hormones and Breast Cancer Risk Factors in Postmenopausal Women: Reanalysis of 13 Studies.” British Journal of Cancer, vol. 105, no. 5, 2011, pp. 709–722. 9. Stanczyk, Frank Z., et al. “Oral, Transdermal and Injectable Hormone Therapy: Pharmacokinetics and Effects on Estrone/Estradiol Ratios.” Menopause, vol. 24, no. 9, 2017, pp. 1080–1090. 10. Santen, Richard J., et al. “Estrogen Bioidentical Hormone Therapy: Route of Administration and Risk.” Journal of Clinical Endocrinology and Metabolism, vol. 105, no. 7, 2020, pp. 2062–2074. 11. Zeleniuch-Jacquotte, Anne, et al. “Postmenopausal Levels of Estrone, Estradiol, and Estrone Sulfate and Breast Cancer Risk.” Cancer Epidemiology, Biomarkers & Prevention, vol. 23, no. 8, 2014, pp. 1531–1539. 12. Dall, Gabriella V., and Christine L. Clarke. “Local Estrogen Biosynthesis and Signaling in Breast Cancer Progression.” Steroids, vol. 78, no. 7, 2013, pp. 639–646. 13. Heald, Anthony H., et al. “Relationships Between Serum Estrone, Insulin Resistance, and Adiposity in Postmenopausal Women.” Clinical Endocrinology, vol. 67, no. 3, 2007, pp. 340–345. 14. Kuiper, George G. J. M., et al. “Estrogen Receptor β Selectivity of Estriol and Implications for Tissue-Specific Effects.” PNAS, vol. 94, no. 17, 1997, pp. 9105–9110. 15. Michnovicz, Joseph J., et al. “Dietary Indoles and Estrogen Metabolism: Effects of Cruciferous Vegetable Intake.” Journal of Nutrition, vol. 134, no. 12, 2004, pp. 3479S–   Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he's helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He's also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you're ready to take your health seriously, this podcast is a great place to start.  

Send us a textJosh Wageman is a returning guest on our show! Be sure to check out his first appearance on episode on 869 of BBR!Josh Wageman is a Clinical Lipid Specialist with multiple doctoral degrees who formerly practiced in Endocrinology. His PhD work focused on cholesterol disturbances in Alzheimer's Disease and, although he also has a Doctorate in Physical Therapy, he is best known for his role in teaching lipid physiology.He serves as an adjunct professor at several medical programs and his goal is to help you, whoever you are, NOT have heart attacks, strokes, and dementia by explaining complicated biochemical concepts in a relatable way!Employing a smorgasbord of metaphors, pictures, and catchphrases, his latest book The Home Security System and the Lipid Neighborhood serves as a valuable reference for clinicians and non-clinicians alike, bringing refreshing relatability to complex biochemical topics. Through a lipid-lens, you'll learn, laugh, and love your way through its pages…and in the end, you'll undoubtedly add “life to your years!”Josh is active in Youth Ministries at Heritage Bible Church in Boise, Idaho, and resides there with his family. He also enjoys Crossfit, basketball, Ultimate Frisbee, and all sports that don't involve skates.Find Dr. Wageman at-Amazon- The Home Security System and the Lipid Neighborhood IG- @wagemanjoshLK- @Josh WagemanFind Boundless Body at- myboundlessbody.com Book a session with us here!

In this episode, we take a closer look at tirzepatide, a type 2 diabetes medication also used to help with weight loss. Postmenopause weight gain can be a normal part of aging, and there are some questions about whether medications like tirzepatide could be useful and safe for postmenopausal women. Host Aaron Lohr talks with Maria Daniela Hurtado Andrade, MD, PhD, assistant professor of medicine at Mayo Clinic Florida, and Regina Castaneda, MD, a research fellow at Mayo Clinic College of Medicine & Science. They presented an abstract at ENDO 2025 titled, “One-Year Real-World Weight Loss Outcomes with Tirzepatide in Postmenopausal Women With and Without Hormone Therapy.” Show notes are available at https://www.endocrine.org/podcast/enp105 — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

Book a FREE functional health discovery call HERE. Many women in midlife are silently battling anxiety, fatigue, and mood swings while doing all the “right” things—working hard, leading, caring for everyone else. But few realize how closely mental health and nutrition are connected.  In this episode, Tanya opens up about her decades-long struggle with anxiety and disordered eating and how undernourishment disrupted her body's ability to make key neurotransmitters. She unpacks how protein and amino acids become the building blocks for mood, energy, and hormones—and why digestion, gut health, and liver function all play a vital role in restoring balance.   Key Topics Covered: Tanya's personal journey with anxiety and bulimia How amino acids become neurotransmitters and hormones The gut-brain-liver connection in mood regulation Protein needs for women in midlife Nutrients essential for neurotransmitter synthesis  How stress and cortisol disrupt serotonin production Faith-based mindset: nourishment as stewardship Resources & References: Frontiers in Endocrinology, 2019 – The Tryptophan Pathway and Serotonin PubMed: Dietary Protein and Brain Serotonin Synthesis ResearchGate: Gut-Brain Axis and Mood Regulation Cleveland Clinic: Understanding Serotonin   I hope this episode blesses you! Xoxo, Tanya Episode Resources: Episode Catalog   My trusted Supplement Dispensary: Aligned Vitality Fullscript Dispensary My trusted Telehealth Peptide Provider:  EllieMD_Tanya Engesether *I do get a small commission when you use one of the above affiliate links. 3 Ways To Connect With Me: 1️⃣COACHING: Are you READY to Lead Well, Live Well and BE Well? Book a FREE discovery call with me to find out more about functional health coaching. It's the accountability and guidance you need to reclaim your health and happiness! ➡︎ https://gracefilledleader.com/coaching   2️⃣ FACEBOOK: Become part of our Supportive Facebook Group. Connect, share, and learn with others navigating life and leadership ➡︎ https://gracefilledleader.com/community   3️⃣ CONTACT: Leave me a question or comment ➡︎ https://gracefilledleader.com/contact   "Yes! Finally, a podcast helping others become the thriving leaders they're meant to be outside of hustle-culture! This is an amazing resource! Thank you so much for sharing and helping us become Spirit-driven, peaceful leaders!"    If you can relate, please consider rating and reviewing my show! It helps me reach more people – just like you – to help them change their future. Don't forget to follow the show so you don't miss any episodes! And, if you're feeling really generous, I'd be SO honored if you would share this podcast with someone.   Click here to view our privacy policy.   Reminder:  The information you hear on this show is not meant to diagnose, treat, cure or prevent disease.  It is for educational purposes only. Always consult with your own health practitioner before you make any changes to your health.

“It's kind of a miracle, frankly,” says Dr. John Buse, a distinguished professor at the University of North Carolina School of Medicine, referring to the effectiveness of GLP-1 receptor agonist medications such as Ozempic in treating type 2 diabetes, promoting significant weight loss, and reducing cardiovascular risk. As a physician scientist for the last three decades at UNC, Dr. Buse has played a key role in ushering in this new era of diabetes care, leading or participating in over 200 clinical studies on this class of drugs and others. “Nothing has impacted diabetes care like the GLP-1 receptor agonists. I have lots of patients whose diabetes was never well controlled who have seen all their metabolic problems essentially resolved.”  In this fascinating conversation with Raise the Line host Lindsey Smith, Dr. Buse not only explains how these drugs work, but also provides a clear-eyed look at side effects, and addresses issues of cost and access. Join us for the remarkable story – including the role played by Gila monsters -- behind one of the biggest developments in medicine over the past several years from a world renowned diabetes researcher and clinician. Mentioned in this episode:UNC School of Medicine If you like this podcast, please share it on your social channels. You can also subscribe to the series and check out all of our episodes at www.osmosis.org/podcast

Long-time Alfacast friend, Dr. Edith​ Ubuntu Chan, joins this episode to discuss her most recent trip to Thailand for a 9 day Dark Room retreat and how this experience has aided her current practice of Blindfold Perception Training.  Now working with adults, she sees this as a powerful tool for transitioning back to our innate Telepathic nature. Edith has devoted her life to exploring the frontiers of Human potential, while sharing her passion as a holistic medicine doctor to help fellow Visionaries awaken to greater possibilities.   Dr. Edith is a doctor of Chinese Medicine and Acupuncture and author of the Amazon #1 bestselling book SuperWellness. Dr. Edith's academic background includes a Doctoral Fellowship at Five Branches University (specializing in Endocrinology and Neuromuscular Medicine), a four-year graduate degree from American College of Traditional Chinese Medicine, and a bachelors in Applied Mathematics with magna cum laude from Harvard University. Show links: https://www.dredithubuntu.com/ Learn The True Nature Of Dis-Ease & How Our Bodies Actually Work: https://alfavedic.com/themyth/ Join Our Private Community And Join In The Discussion: https://alfavedic.com/join-us/ Looking for a career in the healing arts?  Get accredited in Acute Integrative Homeopathy™ https://alfavedic.com/practicioner Start healing yourself and loved ones with ozone! https://alfavedic.com/ozone Protect yourself & your teens from media manipulation & groupthink w/ Dani Katz's Pop Propaganda Course! http://alfavedic.com/poppropaganda Get our favorite blue blocker glasses! Use code 'alfavedic' for 10% off! https://alfavedic.com/raoptics Join Qortal for free, the truly decentralized internet. https://qortal.dev/downloads Learn how to express your law and uphold your rights as one of mankind. https://alfavedic.com/lawformankind Alfa Vedic is an off-grid agriculture & health co-op focused on developing products, media & educational platforms for the betterment of our world. By using advanced scientific methods, cutting-edge technologies and tools derived from the knowledge of the world's greatest minds, the AV community aims to be a model for the future we all want to see. Our comprehensive line of health products and nutrition is available on our website. Most products are hand mixed and formulated right on our off grid farm including our Immortality Teas which we grow on site. Find them all at https://alfavedic.com​​​​​​​​​​​​​​ Follow Alfa Vedic: https://linktr.ee/alfavedic Follow Mike Winner: https://linktr.ee/djmikewinner

With a calcium score of zero, is there any fat in your diet?  Are there any recommended supplements for IBS?What is the safest and most appropriate dose of vitamin D3 for most seniors?

INFINITY Study on the timing of thyroid medication ingestionI have a growth near my eye that is changing in color and becoming crusty. What should I do?I've been suffering from hip pain for the last three years. Any suggestions on what to do?Could toxic exposures like mold cause conditions like low thyroid or autoimmunity?