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Dariush Mozaffarian is the director of the Food is Medicine Institute at the Friedman School of Nutrition Science and Policy at Tufts University and a professor of medicine at Tufts University School of Medicine. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. D. Mozaffarian. Regulatory Policy to Address Ultraprocessed Foods. N Engl J Med 2025;392:2393-2396.
Listen in as Joseph Kim, MD, MPH, MBA; Manish Shah, MD; Martha Grugel, MA, discuss how they manage the prior authorization process for antiobesity agents to improve the quality of their care delivery, including:The information to collect during patient visitsThe available resources to help you submit prior authorizationsThe supporting documents that are often necessary to accompany prior authorizationsHow to address denials and appealsWhen to access manufacturer-based or foundation-based financial assistancePresentersJoseph Kim, MD, MPH, MBAPresidentQ Synthesis, LLCNewtown, PennsylvaniaManish Shah, MDClinical Associate Faculty MS1 PreceptorUniversity of Florida College of MedicineGainesville, FloridaMartha Grugel, MAMedical AssistantWesley Chapel, FloridaLink to full program: https://bit.ly/45P0v8z
Send us a textHey my beautiful friends –This week's conversation was sparked by a funny little tech discovery and a box I mailed — both of which got me thinking about food in a new way. You know how people are always quick to tell you what not to eat? Well, this week we flip the script. I'm sharing thoughts from my own journey and a coach that made me laugh and think — and you'll hear why his words still stick with me to this day. We're keeping things simple, kind, and grounded in something real. I'm not handing out rules, I'm sharing a mindset and maybe even a little inspiration for your next grocery run or packed lunch. And as always, we'll close with a little heart lift — this one from Michael Pollan, who said, “Eat food. Not too much. Mostly plants.”Come hang out with me, and let's talk about what loves us back. References:1. Zhang & Talalay, Frontiers in Nutrition, 20232. Liu, Nutrients, 20233. Viguiliouk et al., Obesity Reviews, 20234. Jenkins et al., AJCN, 20245. Estruch et al., The Lancet Diabetes & Endocrinology, 20236. Guasch-Ferré et al., BMJ, 20237. Yao et al., Nutrients, 20238. Harvard Nurses' Health Study Update, 20239. Anderson et al., AJCN, 202410.Simopoulos, Frontiers in Endocrinology, 202311.Ye et al., Nutrients, 202312.Sonnenburg et al., Cell Metabolism, 202413.Mozaffarian et al., AJCN, 202314.Mastrocola et al., Appetite, 202315.Pollan, M. (2009). In Defense of FoodLet's go, let's get it done. Get more information at: http://projectweightloss.org
Listen in as Joseph Kim, MD, MPH, MBA, interviews Natalie, Orbach, PA-C, to learn about how she implemented patient-centered and individualized treatment plans to improve obesity care at her practice, includingDiscussing weight and how nutrition, physical activity, mental health, and pharmacotherapy strategies can helpMeeting patients where they are at and offering slow, incremental changes that support long-term outcomesReferring patients to community resources and other professionals as needSharing lessons learned for those interested in implementing similar strategies in their practice PresenterJoseph Kim, MD, MPH, MBAPresidentQ Synthesis, LLCNewtown, PennsylvaniaNatalie Orbach, PA-CPhysician AssistantFeirtag & Ramos, PALutherville, Maryland Link to full program: https://bit.ly/45P0v8z
Menopausal hormonal therapy should not be a blanket recommendation for everyone going through menopauseWeight management in women is influenced by hormonal changes throughout life stages.Retrospective analyses can provide insights but have limitations.The wellness industry often oversimplifies complex medical issues.Hormonal replacement therapy may have subtle benefits for weight management.Confounding factors like SSRIs can complicate weight loss efforts.A holistic approach is essential for managing women's health during menopause.Education and awareness are crucial for women navigating menopause.Future research should focus on randomized controlled trials for better clarity.Understanding individual patient experiences is key to effective treatment.Click here to see her studyClick here to follow Dr. Tchang on XClick here to join Dr. Spencer's clinic Vineyard
Whether you've been served an advert for it, or just heard about it in the media, it's likely that 'Ozempic' isn't a totally unfamiliar word. Now often associated with weight-loss, Ozempic is actually the brand name for a drug used to treat diabetes. So what exactly is it, how does it work, and is it safe? We chat to diabetes and endocrinology (hormone) expert Dr Annie de Bray to find out.
How can patients and family members advocate for themselves in today's health care system? What are some of the bias and health equity implications for limb amputations?In this series on healthcare and social disparities, Dr. Jill Wener, a board-certified Internal Medicine specialist, anti-racism educator, meditation expert, and tapping practitioner, interviews experts and gives her own insights into multiple fields relating to social justice and anti-racism. In this episode, Jill interviews Dr. Alyson Myers, a professor and endocrinologist. They discuss Dr. Myers' goal to lower the high rate of amputations of Black and Brown persons with diabetes by using multidisciplinary care and limb salvage techniques. They also discuss risk factors, including social determinants of health, for diabetic foot ulcers and amputee and leg amputations.Dr. Alyson Myers is a Full Professor for the Department of Medicine at Montefiore Einstein in the Bronx. She also is an honorary professor at Universidad Central del Caribe in Bayamon, Puerto Rico. In 2022, she was co-awarded a Center for Diabetes Translational Research grant from the American Diabetes Association to further examine and improve the health outcomes of persons with Diabetic Foot Ulcers (DFU). Her work in diabetic foot ulcers has led to several publications as well as production of a short documentary. Dr. Myers has served two terms on the American Board of Endocrinology, Diabetes and Metabolism. She is also a proud life, silver star member of Alpha Kappa Alpha Sorority, Incorporated.LINKSInstagram: @dr.savealimb**Our website www.consciousantiracism.comYou can learn more about Dr. Wener and her online meditation and tapping courses at www.jillwener.com, and you can learn more about her online social justice course, Conscious Anti Racism: Tools for Self-Discovery, Accountability, and Meaningful Change at https://theresttechnique.com/courses/conscious-anti-racism.If you're a healthcare worker looking for a CME-accredited course, check out Conscious Anti-Racism: Tools for Self-Discovery, Accountability, and Meaningful Change in Healthcare at www.theresttechnique.com/courses/conscious-anti-racism-healthcareJoin her Conscious Anti-Racism facebook group: www.facebook.com/groups/307196473283408Follow her on:Instagram at jillwenerMDLinkedIn at jillwenermd
Our esteemed panel of doctors/scientists will explain common questions about cholesterol. What is cholesterol, and what is its role in the body? Why is it important? What are the various types of cholesterol? How do you interpret your test results? How have recommended levels changed over the years, and why? How do cholesterol-lowering medications work? Are they safe long-term? How does food affect cholesterol levels? These questions and more will be explained in this important program. About the Speakers Dr. Joshua Knowles is a physician-scientist at Stanford. He earned his M.D.–Ph.D. at UNC with Nobuyo Maeda and Nobel Laureate Oliver Smithies, and his internal medicine residency and fellowship at Stanford University primarily. Robert H. Lustig, M.D., M.S.L., is emeritus professor of pediatrics in the Division of Endocrinology, and member of the Institute for Health Policy Studies at UCSF. Dr. Lustig is a neuroendocrinologist, with expertise in obesity, diabetes, metabolism, and nutrition. Dr. Ethan Weiss is a cardiologist whose special interests include preventive cardiology, the genetics of coronary disease, risk assessment for heart conditions and heart disease in the young. A Nutrition, Food & Wellness Member-led Forum program. Forums at the Club are organized and run by volunteer programmers who are members of The Commonwealth Club, and they cover a diverse range of topics. Learn more about our Forums. OrganizerPatty James Learn more about your ad choices. Visit megaphone.fm/adchoices
The future of Public Health depends on protection against unrestrained corporate power. A sicker humanity means increased pain and suffering at large. In the past, we have identified numerous exposures that have made us sick, many of which are addictive, and created shield laws to protect the corporations that peddle them. We also know it's our most toxic addictions that are killing the planet and its people currently, whether due to climate crisis or ingesting harmful chemical substances. When Big Tobacco tried to convince the world that ingesting tar and nicotine made people healthier (“9 out of 10 doctors smoke Camels”), science revealed otherwise and insisted upon laws to regulate the industry more closely. Robert H. Lustig, M.D., M.S.L suggests that we consider a similar strategy for sugar, particularly the fructose or refined fructose molecules commonly found to be overdosing society through packaged products. Per his biography, he wants to help “fix the food supply any way he can.” Lustig explaine that one of the essential patterns to recognize in battling addiction is the dichotomy between pleasure vs. happiness. Dr. Lustig is an Emeritus Professor of Pediatrics in the Division of Endocrinology and a Member of the Institute for Health Policy Studies at UCSF. He is a neuroendocrinologist with expertise in obesity, diabetes, metabolism, and nutrition. Learn more about your ad choices. Visit megaphone.fm/adchoices
In this episode, Dr. Dodell is talking with us about hormones. We dig into what they are, why they are important, how nutrition can positively or negatively impact our hormones and MORE!Gregory Dodell is a Board Certified in Internal Medicine and Endocrinology. President and Owner of Central Park Endocrinology, PC. He went to Albany Medical College, for his MD and did Internal Medicine and Endocrinology Training at St. Luke's Roosevelt, Columbia University.In today's episode we cover:-Endocrinology & the study of hormones-How under-fueling can impact hormones & health-The role of testosterone & our health-Cortisol & stress management-Navigating & review of research on hormone replacement therapy-Weight stigma and our healthYou can find Dr. Dodell on Instagram Learn more about Dr. Dodell's practice centralparkendocrinology.com-----Power Up - self paced nutrition course for runners & triathletes. Learn more here. Enter discount code "podcast" at checkout for $50 off for podcast listeners.Subscribe to our newsletterFollow us on Instagram @befueledsportsnutrition
Márta Korbonits, Professor of Endocrinology at the Queen Mary University in London, on a 'tug of war' over the body of an Irishman who was one of the tallest men in the world when he died in the 1700s.
Aubrey converses with Dr. Ankia Coetzee, Cape Town-based endocrinologist and former president of (SEMDSA)the Society of Endocrinology, Metabolism, and Diabetes in South Africa, about all things thyroid. What it does, how it affects your health, and why thyroid disorders often go undiagnosed. THE AUBREY MASANGO SHOW BOILERPLATE The Aubrey Masango Show is presented by late night radio broadcaster Aubrey Masango. Aubrey hosts in-depth interviews on controversial political issues and chats to experts offering life advice and guidance in areas of psychology, personal finance and more. All Aubrey’s interviews are podcasted for you to catch-up and listen. Thank you for listening to this podcast from The Aubrey Masango Show. Listen live on weekdays between 20:00 and 24:00 (SA Time) to The Aubrey Masango Show broadcast on 702 https://buff.ly/gk3y0Kj and on CapeTalk between 20:00 and 21:00 (SA Time) https://buff.ly/NnFM3Nk Find out more about the show here https://buff.ly/lzyKCv0 and get all the catch-up podcasts https://buff.ly/rT6znsn Subscribe to the 702 and CapeTalk Daily and Weekly Newsletters https://buff.ly/v5mfet Follow us on social media: 702 on Facebook: https://www.facebook.com/TalkRadio702 702 on TikTok: https://www.tiktok.com/@talkradio702 702 on Instagram: https://www.instagram.com/talkradio702/ 702 on X: https://x.com/Radio702 702 on YouTube: https://www.youtube.com/@radio702 CapeTalk on Facebook: https://www.facebook.com/CapeTalk CapeTalk on TikTok: https://www.tiktok.com/@capetalk CapeTalk on Instagram: https://www.instagram.com/ CapeTalk on X: https://x.com/CapeTalk CapeTalk on YouTube: https://www.youtube.com/@CapeTalk567 See omnystudio.com/listener for privacy information.
Hey Diabuddy thank you for listening to show, send me some positive vibes with your favorite part of this episode.In today's episode, I sit down with Dr. Ladan Davallow. Dr. Davallow is a pediatric endocrinologist, certified coach, and mom of three boys. She's the founder of Diabright, a coaching program that helps parents of kids with Type 1 Diabetes stop chasing rollercoaster blood sugars and finally feel confident in their child's care. Using her proven 3-step method, she teaches parents how to decode their child's unique patterns—so they can stop feeling like they're failing at a job they never asked for, and their T1D kids can finally just be kids again!Dr. Ladan Davallow InstagramDiaBright's Facebook PageHer Free MasterClassCoach Ken's Resources:Website: www.simplifyingdiabetes.comNewsletter Sign Up"More Than A1C" - My Signature Coaching ProgramThe Diabetes Nutrition Master CourseThe 5-Pillars Of Diabetes Success WorksheetSet Up a Free Call...Apparel StoreSupport & Donate To The PodcastThe T1D Exchange Registry is a research study, conducted over time, for individuals with type 1 diabetes and their supporters. Participants volunteer to provide their data for Diabetes research. Once enrolled, Registry participants have the opportunity to sign up for other studies on various topics related to type 1 diabetes.You can make an impact on the future of Diabetes now! Fill out an online survey and gain access to tons of new research and the online portal. It only takes 10-15 minutes.Have a question, send me a DM or email. I'd love to connect and answer any questions you have.You can find the show on any platform you listen to your podcasts!Don't forget to click on that subscribe button and leave a 5-star review, so you're notified when new episode drop every week.Questions about diabetes, don't hesitate to reach out:Instagram: @CoachK3NInstagram: @thehealthydiabeticpodFacebook: @Simplifying Life With DiabetesEmail: ken@simplifyingdiabetes.comPodcast Disclaimer: Nothing that you hear on The Healthy Diabetic Podcast should be considered medical advice or otherwise; please always consult your medical TEAM before making any changes to your Diabetes management.Support the show
Do you find lipids fascinating? Exciting? Full of whimsy? My guest today does and after listening to this episode, I think you will, too (at least a little bit)!Josh Wageman is a prior physical therapist turned physician associate. He works as a Clinical Lipid Specialist and formerly practiced in Endocrinology prior to transitioning to a Medical Science Liaison. His PhD work focused on cholesterol disturbances in Alzheimer's Disease. Josh translated his PhD studies and clinical work into his book, The Home Security System and the Lipid Neighborhood: Un-Complicating Cholesterol and Cardiovascular Disease. Josh's goal is to help people not have heart attacks, strokes, and dementia by explaining complicated biochemical concepts in a relatable way. He's even been known to write rap songs and pop parodies about lipids. Tune in to learn the top things you can start TODAY to prevent heart attacks, strokes, and dementia. You might even laugh along the way.BUY JOSH'S BOOK: The Home Security System and the Lipid Neighborhood: Un-Complicating Cholesterol and Cardiovascular DiseaseSPONSORS
In this episode of Health Matters, Dr. Mary Rosser, a gynecologist at NewYork-Presbyterian and Columbia, explains perimenopause, breaking down what symptoms are normal, when it's time to see a doctor, and the best options for managing some of the more challenging symptoms of perimenopause. ___Dr. Mary L. Rosser, M.D., Ph.D., NCMP is the Director of Integrated Women's Health at NewYork-Presbyterian/Columbia University Irving Medical Center and the Richard U. and Ellen J. Levine Assistant Professor of Women's Health (in Obstetrics and Gynecology) at Columbia University Vagelos College of Physicians & Surgeons. She joined the faculty of Obstetrics and Gynecology at Columbia University in April 2018 to provide routine gynecology care and to further develop a comprehensive well-woman program. She has been a practicing obstetrician gynecologist for more than 20 years, starting in private practice and then joining the faculty at Montefiore Medical Center in Bronx, NY. While at Montefiore, she created, launched, and led the forty-person Division of General Obstetrics and Gynecology. Dr. Rosser received her undergraduate degree at Emory University and a Ph.D. in Endocrinology at the Medical College of Georgia. She attended Wake Forest University School of Medicine and completed her residency at Emory University. She is also a NAMS Certified Menopause Practitioner, able to provide high-quality care for patients at menopause and beyond.Primary care and heart disease in women have always been areas of focus for Dr. Rosser. She conducted basic science research on heart disease during graduate school and was the Chair of the "Women & Heart Disease Physician Education Initiative" for District II of the American College of Obstetrics & Gynecology. She continues to conduct clinical studies around patient awareness and understanding of heart disease and well-woman care. Dr. Rosser serves on the Medical Leadership Team of the Go Red for Women movement of the American Heart Association and she is ACOG's liaison to the American College of Cardiology.___Health Matters is your weekly dose of health and wellness information, from the leading experts. Join host Courtney Allison to get news you can use in your own life. New episodes drop each Wednesday.If you are looking for practical health tips and trustworthy information from world-class doctors and medical experts you will enjoy listening to Health Matters. Health Matters was created to share stories of science, care, and wellness that are happening every day at NewYork-Presbyterian, one of the nation's most comprehensive, integrated academic healthcare systems. In keeping with NewYork-Presbyterian's long legacy of medical breakthroughs and innovation, Health Matters features the latest news, insights, and health tips from our trusted experts; inspiring first-hand accounts from patients and caregivers; and updates on the latest research and innovations in patient care, all in collaboration with our renowned medical schools, Columbia and Weill Cornell Medicine. To learn more visit: https://healthmatters.nyp.org
Pediatric Insights: Advances and Innovations with Children’s Health
In this episode, we dive into the importance of autoantibody screening for Type 1 Diabetes (T1D) and its potential for early detection. Learn how identifying at-risk individuals can improve patient outcomes, reduce complications and help guide timely interventions.
Send us a textDr. Holly Thacker dives deep into the world of endocrinology and anti-aging with guest Dr. Elena Christofides. Dr. Christofides highlights how hormonal health significantly impacts women's well-being as they age. The discussion covers common health challenges women face, potential treatments, and the importance of personalized assessments to optimize health through lifestyle and pharmacological means. • Explanation of endocrinology and its roles in overall health • Common health concerns for midlife women • Importance of understanding aging vs. hormonal imbalance • Overview of Metformin and emerging treatments like rapamycin • The significance of mitochondrial health • Connection between environmental factors and health optimization • Empowerment through health advocacy and informed choices For more information on Dr. Elena Christofides, visit endocrinology-associates.com. You can listen to Dr. Christofides podcast on medcentral.com.Fit, Healthy & Happy Podcast Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle from Colossus...Listen on: Apple Podcasts SpotifySupport the show
Forever Young Radio Show with America's Natural Doctor Podcast
To help us unpack all the research and studies we have Dr. Stengler joining us today.In addition to authoring 30 books on health and several best-sellers such as “The Natural Physician's Healing Therapies,” “Prescription for Natural Cures,” “Prescription for Drug Alternatives,” and “Outside the Box Cancer Therapies,” Dr. Stengler has been published in several peer-reviewed medical journals such as The International Journal of Family & Community Medicine, Endocrinology & Metabolism International Journal, and Journal of Nutritional Health & Food Engineering.Dr. Stengler's, NMD. The newest book is called, The Holistic Guide to Gut Health. A comprehensive yet accessible approach to healing leaky gut and the many uncomfortable symptoms it causes. Dr Stengler is also the founder of The Stengler Center for Integrative Medicine.Talking Points:Palmitoylethanolamide (PEA), is a naturally occurring fatty acid derivative made in the body and found in small amounts in foods. Several human studies have demonstrated that PEA has broad-spectrum pain-relieving properties, anti-inflammatory effects, and nerve protection.PEA was first discovered in 1957 by scientists at Merck Sharp & Dohme, who isolated it from egg yolk, peanut meal, and soy lecithin. They found that PEA had anti-inflammatory properties in guinea pigs.However, PEA's role as a potential therapeutic agent was not widely recognized until 1993, when Rita Levi-Montalcini and her colleagues published research that suggested PEA has anti-inflammatory properties. Levi-Montalcini's group termed PEA an autocoid local injury antagonist (ALIA), and suggested that it acts locally to counteract injuryMultiple studies have demonstrated that PEA improves all sorts of pain. For example, a 2023 analysis of 11 studies found that PEA improved pain of various conditions, including muscle and joints, nerves, gynecological, and digestive. In terms of joint pain, a high-quality study demonstrated that PEA significantly reduced adult joint pain compared to placebo. Moreover, 8 clinical trials demonstrated that PEA was effective for low back pain, sciatica, and carpal tunnel syndrome. Even migraine headache pain was shown in published research to be improved with PEA.Lipid mediators help to balance the immune, nervous, and endocrine systems, affecting pain pathways related to inflammation. But unfortunately, due to changing diets, many of us do not get the nutrition and activity we need to make enough PEA ourselves.Supplemental PEA, by Levagen+ is properly formulated for optimal bioavailability, 75% more bioavailable to cell receptors than dietary forms. Levagen+ liposomal delivery of PEA has been clinically studied and shows benefits in joint pain, nerve pain, migraine, infections, sleep, and cognitive function.Learn more about Emerald Labs PEA+ Levagen Use the code: Forever and get 20% off your order.
In this episode of Better Than Before Breast Cancer™, we're talking about a common and little-talked-about side effect of breast cancer treatment and day-to-day living: digestive changes. If you've experienced bloating, reflux, fatigue, or that uncomfortable feeling of fullness after eating, this episode is for you. You'll learn why hypochlorhydria (low stomach acid) is often misdiagnosed as high stomach acid, how breast cancer treatments like chemotherapy, radiation, and hormonal therapy contribute to poor digestion, and why treating symptoms with acid-blocking medications might be doing more harm than good. Most importantly, we'll cover simple, nurturing steps — like mindful eating habits and nutrient support — to help you feel better, absorb more nutrients, and reconnect with your body's healing capacity.
Piper hosts Plaidcast LIVE! from The Madeira School in McLean, VA with guests Phoebe Lang, Dr. Lisa Metcalf, DVM/MS and Dr. Kimberly Brokaw, DVM. Brought to you by Taylor, Harris Insurance Services.Host: Piper Klemm, publisher of The Plaid HorseGuest: Phoebe Lang was born and raised in the Washington, DC area and ignited her passion for horses at Madeira's summer riding program when she was seven years old. Upon graduating from Madeira in 1985, Phoebe attending Kenyon College and then moved to San Francisco, raised her three children, and started riding again in her 30's. Phoebe has devoted the past 25 years to pursuing elite-level show jumping throughout the US, Canada, and Europe, reaching the FEI 3* level. She built her farm and training business, Zeitgeist Equestrian and Equstech, in Petaluma, CA, and has worked on developing several equine therapeutic devices. While Phebe has retired from riding competitively, she still owns and cares for six horses and has been spending time launching the breeding career of one of her former grand prix stallions. Guest: Dr. Lisa Metcalf, DVM/MS grew up on a horse farm in northern VA, and her lifelong passion for horses shaped a distinguished academic and professional journey. After attending Madeira and then earning her BA in Biology from Wesleyan University, Dr. Metcalf went on to obtain her DVM from The Virginia-Maryland Regional College of Veterinary Medicine and her MS in Endocrinology from UC Davis. Dr. Metcalf is a decorated and board-certified theriogenologist; a specialist in the practice of animal reproduction. Beyond her clinical work, she has held influential roles with organizations such as the Oregon Veterinary Racing Commission, the American Association of Equine Practitioners, and the Portland Mounted Patrol Unit. An internationally sought-after speaker and widely published author, Dr. Metcalf brings deep expertise, passion, and perspective to the world of veterinary reproductive medicine. Guest: Dr. Kimberly Brokaw DVM's passion for horses and animal science, fostered by the Madeira school, led her to pursue her BS in animal science at the University of Maryland. She then earned her Doctorate from Virginia-Maryland College of Veterinary Medicine. Following her 15 years of service at the Walkersville Veterinary Clinic of Maryland, she currently brings her expertise to two impactful roles: as a Veterinary Medical Officer for the Food and Drug Administration (FDA) and as a passionate team member at Gentle Giants Draft Horse Rescue in Mount Airy, MD, a nonprofit organization devoted to rescuing and rehabilitating draft horses.Title Sponsor: Taylor, Harris Insurance ServicesSubscribe To: The Plaid Horse MagazineSponsors: Foxhall Equine and Great American Insurance Group Join us at an upcoming Plaidcast LIVE!
Doctor's Farmacy with Mark Hyman, MD: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Cutting-edge medical advances are unlocking new ways to slow aging and enhance health. Plasmapheresis removes harmful inflammatory molecules, toxins, and cellular waste from plasma, helping to reduce biological aging and improve resilience. Muse cells, a powerful form of stem cell therapy, show promise in regenerating tissue and treating complex conditions like ALS and stroke. And peptides—small, naturally occurring signaling molecules—support healing, immune balance, and cellular repair, offering practical tools for longevity and optimized health. In this episode, I talk with Dr. Darshan Shah, Dr. Adeel Khan, and Dr. Edwin Lee about medical advancements that are the ultimate longevity biohacks. Dr. Darshan Shah is a board-certified surgeon, longevity medicine expert, author, and founder of Next Health—the world's largest Health Optimization and Longevity clinic. He has performed over 20,000 surgical procedures and advised thousands on extending healthspan and lifespan. A prodigy in medicine, Dr. Shah earned his MD at 21 and trained at the Mayo Clinic. He has since launched multiple health ventures, authored a book, and patented medical devices. Committed to ongoing learning, he holds alumni status at Harvard Business School and Singularity University. Dr. Shah is a sought-after speaker on health and longevity. Dr. Adeel Khan, M.D. is a cell and gene therapy specialist with a visionary approach that is changing the way we perceive healthcare worldwide. Khan has cemented his reputation as a regenerative medicine expert and a driven entrepreneur. Dr. Edwin Lee is a board-certified endocrinologist, author, and international speaker specializing in hormonal balance, regenerative, and functional medicine. He founded the Institute for Hormonal Balance in Orlando in 2008 and completed fellowships in Critical Care and Endocrinology at the University of Pittsburgh. Dr. Lee is the lead investigator of an IRB-approved senolytic study exploring compounds like Dasatinib, Quercetin, and Fisetin, and recently published the first human trial using BPC157 for knee pain. He is an assistant professor at the University of Central Florida College of Medicine, co-founder of the Clinical Peptide Society, and founder of SavePeptides.org. His latest book is The Fountain of Youth with Peptides. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%. Full-length episodes can be found here: This Breakthrough Blood Therapy Could Add Years To Your LifeStem Cells & Peptides: The Secret to Reversing Chronic Pain and Aging?How Peptides Enhance Healing and Longevity
Listen in as Joseph Kim, MD, MPH, MBA, interviews Sejal Desai, MD, DABOM, to learn about how she implemented virtual support groups to improve obesity care at her practice, including:Dedicating 5 support groups with chat features to obesity-specific topics (eg, sleep, nonscale wins)Moderating these chats to ensure no misinformation is shared and a positive, safe space is maintainedExpanding to include other virtual options that allow patients to engage more in their careUtilizing free and subscription-based services to aid in marketing effortsSharing lessons learned for those interested in implementing similar virtual options for their patients PresentersJoseph Kim, MD, MPH, MBAPresidentQ Synthesis, LLCNewtown, PennsylvaniaSejal Desai, MD, DABOMBoard-Certified Obesity Medicine PhysicianOwner & Medical DirectorTula Medical Weight Loss & WellnessKaty, TexasLink to full program: https://clinicaloptions.com/content/qi-resource-hub
In this thought-provoking episode of Metabolic Matters, Dr. Nasha Winters sits down with Dr. Robert Lustig, a pioneer in neuroendocrinology and metabolic research, to challenge the most deeply held assumptions about health, nutrition, and chronic disease.Dr. Lustig shares the personal journey and clinical breakthroughs that led him to uncover how our modern food system, misinformed science, and biochemical dysfunction have hijacked not just our bodies, but our brains. From leptin resistance and childhood obesity to mitochondrial failure and insulin overload, this conversation is packed with powerful insights for anyone seeking to understand the true roots of metabolic dysfunction.Why obesity is not a result of gluttony or sloth — but a hormonal and neurological responseHow mitochondrial dysfunction underlies chronic disease, from cancer to diabetesThe critical difference between food science, nutrition, and metabolic healthWhat happens when insulin levels rise — and how to bring them downThe story behind Freeing the Hostage Brain, Dr. Lustig's upcoming bookMetabolic health, mitochondria, insulin resistance, fructose, leptin, obesity, chronic disease, Dr. Robert Lustig, ultra-processed food, root cause medicine, neuroendocrinology, nutrition, energy balance, brain health.Dr. Robert Lustig is Professor Emeritus of Pediatrics in the Division of Endocrinology at the University of California, San Francisco (UCSF). A globally recognized expert in neuroendocrinology and nutrition, he has spent decades researching childhood obesity, insulin resistance, and the food industry's role in modern disease. His books include Fat Chance, Sugar: The Bitter Truth, Metabolical, and the upcoming Freeing the Hostage Brain.Dr. Lustig's books: Metabolical, Sugar: The Bitter Truth, Fat ChanceUpcoming book: Freeing the Hostage Brain (Fall 2025)How Sugar & Processed Foods Impact your Health: https://www.youtube.com/watch?v=n28W4AmvMDEConnect with Dr. Lustig:
Cutting-edge medical advances are unlocking new ways to slow aging and enhance health. Plasmapheresis removes harmful inflammatory molecules, toxins, and cellular waste from plasma, helping to reduce biological aging and improve resilience. Muse cells, a powerful form of stem cell therapy, show promise in regenerating tissue and treating complex conditions like ALS and stroke. And peptides—small, naturally occurring signaling molecules—support healing, immune balance, and cellular repair, offering practical tools for longevity and optimized health. In this episode, I talk with Dr. Darshan Shah, Dr. Adeel Khan, and Dr. Edwin Lee about medical advancements that are the ultimate longevity biohacks. Dr. Darshan Shah is a board-certified surgeon, longevity medicine expert, author, and founder of Next Health—the world's largest Health Optimization and Longevity clinic. He has performed over 20,000 surgical procedures and advised thousands on extending healthspan and lifespan. A prodigy in medicine, Dr. Shah earned his MD at 21 and trained at the Mayo Clinic. He has since launched multiple health ventures, authored a book, and patented medical devices. Committed to ongoing learning, he holds alumni status at Harvard Business School and Singularity University. Dr. Shah is a sought-after speaker on health and longevity. Dr. Adeel Khan, M.D. is a cell and gene therapy specialist with a visionary approach that is changing the way we perceive healthcare worldwide. Khan has cemented his reputation as a regenerative medicine expert and a driven entrepreneur. Dr. Edwin Lee is a board-certified endocrinologist, author, and international speaker specializing in hormonal balance, regenerative, and functional medicine. He founded the Institute for Hormonal Balance in Orlando in 2008 and completed fellowships in Critical Care and Endocrinology at the University of Pittsburgh. Dr. Lee is the lead investigator of an IRB-approved senolytic study exploring compounds like Dasatinib, Quercetin, and Fisetin, and recently published the first human trial using BPC157 for knee pain. He is an assistant professor at the University of Central Florida College of Medicine, co-founder of the Clinical Peptide Society, and founder of SavePeptides.org. His latest book is The Fountain of Youth with Peptides. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%. Full-length episodes can be found here: This Breakthrough Blood Therapy Could Add Years To Your LifeStem Cells & Peptides: The Secret to Reversing Chronic Pain and Aging?How Peptides Enhance Healing and Longevity
Sexual wellness is a constantly evolving topic that can be challenging to fully grasp. With numerous opinions surrounding this aspect of health, it is essential to choose an approach that truly fits your individual needs. So, what does it mean to make informed decisions about sexual health within the framework of integrative medicine? Dr. Cristina Romero-Bosch and Dr. John A. Robinson join the podcast to provide insights… Dr. Robinson is the Chief Medical Officer at The Hormone Zone and a Board Certified Naturopathic Medical Doctor specializing in Hormone Replacement Therapy, Anti-Aging Medicine, Functional Medicine, and Longevity Medicine. He has been practicing healthcare for more than 29 years — always striving to provide a very human yet scientifically practical approach to medicine. Dr. Bosch is the Medical Officer at The Hormone Zone and obtained her medical degree at the Southwest College of Naturopathic Medicine and her residency at Yale University/Bridgeport College of Naturopathic Medicine in Alternative Medicine Women's Health and Endocrinology. She says her work is “not a medical practice but a way of life, a philosophy that provides tangible answers to questions of health as well as hope that if one path does not lead to resolution then through innovation and understanding one's body healing will always be an option.” In this episode, we discuss: The role that hormones play in health optimization, and why they are often dysregulated in young people. The two primary issues that both men and women struggle with. The various forms of erectile dysfunction that men face as they age. How hormone replacement therapy helps patients reclaim their health. The importance of intimacy for maintaining sexual relationships. Dr. Robinson and Dr. Bosch run their private practice in Scottsdale, Arizona, called The Hormone Zone – as well as a management company that has locations across the United States. Be sure to follow them on Instagram @thesexdocs and listen to their podcast! All other links can be found here. Episode also available on Apple Podcasts: apple.co/30PvU9C
There has been a fundamental shift in understanding metabolic health and chronic disease, particularly Type 2 diabetes, challenging long-standing dietary dogma by emphasizing that insulin resistance is largely driven by overconsumption of refined carbohydrates, not dietary fat or red meat. While highlighting the success of carbohydrate restriction and ketogenic approaches, nutrition is being seen as a powerful tool for reversing diabetes—often more effective and sustainable than conventional medication. The implications are far-reaching, not only for individual health outcomes, but also for reshaping public health strategies in addressing today's chronic disease epidemic. In this episode, I speak with Gary Taubes, Sami Inkinen, and Dr. Greeshma Shetty about an approach to treating Type 2 Diabetes that works. I also discuss how red meat is not to blame, but we should be looking at high sugar and starch diets. Gary Taubes is an award-winning science and health journalist, and co-founder and director of the Nutrition Science Initiative (NuSI). He is the author of The Case Against Sugar, Why We Get Fat, Good Calories, Bad Calories, and, most recently, The Case for Keto. Gary is a former staff writer for Discover and correspondent for Science. He has written three cover articles on nutrition and health for The New York Times Magazine, and his writing has also appeared in The Atlantic, Esquire, and numerous "best of" anthologies, including The Best of the Best American Science Writing (2010). He has received three Science in Society Journalism Awards from the National Association of Science Writers, and is also the recipient of a Robert Wood Johnson Foundation Investigator Award in Health Policy Research. He lives in Oakland, CA. Sami Inkinen is the CEO and Co-Founder of Virta Health, a pioneer in reversing diseases like obesity and type 2 diabetes through a nutrition-first approach. Sami's personal connection to diabetes and passion to advance global health was the motivation behind Virta and its innovative care model. Previously, Inkinen was the co-founder of the leading online real estate marketplace Trulia, serving as its COO and president and board member until its IPO and eventual sale to Zillow Group. Dr. Greeshma Shetty, board certified in Internal Medicine and Endocrinology, currently serves as a Lead Clinician in the Virta Medical Group and the Director of Quality and Safety at Virta Health. Prior to joining Virta, she was clinical physician educator at Harvard Medical School, where she directed the combined Joslin - Beth Israel Deaconess Endocrine Fellowship program and Co-Directed the Asian American Diabetes Initiative. She is dedicated to clinical excellence, leveraging health technology, transforming healthcare delivery, driving health equity and building high performing teams. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%. Full-length episodes can be found here: The Evolution of Diabetes Treatment How to Reverse Diabetes Naturally Does Red Meat Cause Type II Diabetes?
In this episode of Sky Women's Health Podcast, Dr. Carolyn Moyers welcomes endocrinologist Dr. Lindsey VanDyke, founder of The Advanced Institute for Diabetes and Endocrinology. Together, they dive deep into the often misunderstood topic of testosterone use in women — particularly its role in sexual desire, libido, and overall well-being.We cover:What testosterone does for women's healthHow low testosterone may impact sexual function and quality of lifeWho might be a candidate for testosterone therapyCommon myths and concerns about testosterone useThe importance of personalized hormone managementHow to approach conversations about sexual desire with your healthcare providerIf you've ever been curious about hormone therapy beyond estrogen, this conversation is for you!
Welcome to Perimenopause WTF!, brought to you by Perry—the #1 perimenopause app and safe space for connection, support, and new friendships during the menopause transition. You're not crazy, and you're definitely not alone! Download the free Perry App on Apple or Android and join our live expert talks, receive evidence-based education, connect with other women, and simplify your perimenopause journey.Today's Episode“From Medical to Lifestyle: Building Your Perimenopause Weight Loss Toolbox ”Weight gain during perimenopause and menopause is a huge concern for women; a real source of frustration. There are reasons behind it, oftentimes, hormonal reasons during this season as Dr. Disha Narang and Dr. Rocio Salas-Whalen explain. Listen in as they discuss why this happens to women and the various ways one can combat the dreaded visceral fat and weight gain!Discover What's New at Perry!Whether you're navigating perimenopause or empowering others as a women's health professional, Perry has something for you. Explore our latest features:
In this video, I debunk all the recovery myths that keep you stuck. They might seem to work temporarily, but in the long run, they are a waste of your time. Whether you have long COVID, ME/CFS, Lyme, adrenal fatigue, chronic fatigue, fibromyalgia, or MCAS, this 20-minute video will save you years of time.Join our Q&A: https://releasecfs.com/contact/ Blog: https://releasecfs.com/developing-the-cfs-personality/Time Stamps: 00:59 The myth of the magic recovery moment 01:48 The myth of the baseline and pacing 03:40 The Cell Danger Response (CDR) by Dr. Robert Naviaux 04:22 Overcomplicating your recovery and healing journey 05:01 How to simplify your condition and understand different symptoms 07:15 The myth of the false danger response 07:44 The MindBody theory and lots of research 11:57 What is the best way to heal? 14:52 Myth - There is something wrong with your body (infections, immune system, genetics, mitochondria 16:42 The myth about Brain Retraining 19:04 Myth- Different things work for different people 19:46 The 4 steps to heal in the Release Program 21:13 Myth - Calming down the nervous system 21:36 Final Thoughts and tips.
From a medical family in Puerto Rico, Dr. Padilla rocketed her way into medical school at the age of 20. There, her age combined with her sex and race to get a little extra dose of condescension from some of her colleagues. Listen to her story about how she dealt with these challenges, and what her day-to-day looks like after completing her residency in internal medicine, and then a fellowship in endocrinology.
Sarah Allan, MD, a Le Bonheur pediatric endocrinologist, discusses practical lifestyle changes, risk factors to watch for and the latest treatments available for Type 2 diabetes. This episode empowers parents and caregivers to make informed choices for a heathier future.
Listen in as Joseph Kim, MD, MPH, MBA, interviews Sophia Kwon, MD, to learn about how she implemented a documentation shortcut at her institution to improve obesity care, including:Creating an obesity checklist within the electronic health recordTraining staff to correctly use this checklist and broach obesity topics with patientsGarnering feedback to ensure this checklist did not add to note fatigue or burnout among staffSharing lessons learned for others interested in implementing a similar documentation shortcutPresenterJoseph Kim, MD, MPH, MBAPresidentQ Synthesis, LLCNewtown, Pennsylvania Sophia Kwon, MDInternal Medicine AttendingRiverside University Health System AttendingLoma Linda University Health Associate FacultyLoma Linda, California
See all the Healthcasts at https://www.biobalancehealth.com/healthcast-blog Menopausal Symptoms I waited to announce the emerging research regarding the safety of post-menopausal hormone replacement therapy for breast cancer patients suffering from severe menopausal symptoms until the research finally supported my belief that women have the right to receive the treatment that they need if they accept the risks of that treatment. The past year of research (2024-2025) has produced a significant amount of research demonstrating the health risks associated from not taking hormone replacement therapy, as well as the safety of using testosterone after breast cancer and the limited risks of hormone replacement therapy following breast cancer. I have practiced women's medicine for over 40 years, and I believe that female patients should have the right to receive post-menopausal hormone therapy if they understand and accept the associated risks and benefits, as long as it is administered safely. Let me pause here to discuss how doctors ethically make decisions about treatment. First, the aim of medical treatment is to improve health and longevity while alleviating symptoms. It is a doctor's responsibility to evaluate, treat, and advise patients on the best course of therapy based on their medical training, practical experience, and the latest research. However, the third factor is often overlooked when advising patients about hormone replacement therapy after breast cancer. Doctors determine the best course of treatment by using this information and weighing the benefits of a treatment against its risks. We are trained to provide this information to patients to facilitate informed decision-making with the patient, not for the patient. This process requires time that doctors no longer have. Ah, and therein lies the problem. Doctors are trained to follow research related to the diseases and conditions they treat and to integrate that research into their practice. The basic decision-making process involves weighing the benefits of treatment (or no treatment) against the associated risks. When the benefits of a treatment outweigh its risks, it is recommended to the patient. “Recommended” means the doctor, based on current knowledge, believes it to be safer and more effective for the patient's health to pursue a specific treatment. However, this does not imply that the patient must follow the doctor's advice. A patient is autonomous and can assess the risks and benefits once informed, allowing them to refuse a treatment or request one that falls outside current medical guidelines. Doctors do not have to embark on a treatment they do not believe is beneficial or safe. Doctors have autonomy as well! Doctors in mainstream medicine adhere to “medical guidelines” established by our specialties, which represent the minimum level of care expected from a physician. However, these guidelines are often decades behind current research, meaning that the risks and benefits communicated to a patient may be outdated. A legal requirement known as informed consent mandates that a doctor inform the patient or include this information in a consent form that the patient reads and signs, detailing the procedure or treatment. If the treatment is newer than the guidelines, it is categorized as “off-label.” It is essential for the doctor to inform the patient that the treatment does not conform to current guidelines, and the patient must acknowledge the known risks associated with the treatment. At BioBalance Health®, we often find ourselves ahead of the guidelines, and my experience indicates it may take up to 20 years for the guidelines to catch up with us. Much of our treatment is considered off-label because it is current and ahead of the guidelines. It is superior to other treatments and remains safe, but risks are inherent in every treatment! Now, let's return to breast cancer and the roles of estradiol, testosterone, and progesterone replacement. Here are the facts about breast cancer: Most breast cancer patients are post-menopausal, and have symptoms of menopause Not all types of breast cancer are stimulated by estradiol or progesterone, and therefore for these cancers hormone replacement therapy is safe. Breast Cancer patients with negative nodes who have had a bilateral mastectomy are candidates for hormone replacement therapy after their treatment. The risks of estrogen replacement for ER+ breast cancer patients may promote the growth of cancer cells, while testosterone replacement lowers the risk of recurrence and alleviates certain menopausal symptoms. When testosterone is combined with estradiol, the risk of developing breast cancer in all women is reduced. Testosterone enhances the quantity and activity of cancer-fighting T-killer and T-helper white blood cells. All breast cancer patients can manage menopause symptoms using testosterone pellet therapy and vaginal estrogen without an increased risk of recurrence. Do you remember when I mentioned that the risks of treatment should be balanced with the benefits of that same treatment? Recently, numerous research articles have outlined the benefits of estradiol treatment, which I included in my 2017 book, “The Secret Female Hormone: How Testosterone Replacement Can Change Your Life.” In early 2025, the safety of taking estradiol for menopausal women confirmed the less publicized research that had come before. The Journal of Endocrinology and Metabolism reported that women who underwent estradiol replacement after the age of 60 live 20% longer than those who do not take hormone replacement therapy. This challenges the guideline that advises OB-GYNs to discontinue hormone replacement therapy before the age of 60. The Benefits of Estrogen replacement after menopause, based on multiple research studies over the last 20 years is as follows: ERT alleviates symptoms such as dry vagina, painful intercourse, insomnia, hot flashes, and night sweats. Estrogen replacement prevents and treats osteoporosis in women. Testosterone replacement in women with osteoporosis can reverse the process of bone loss, bringing bone back to normal strength and decreasing fracture risk. Non-oral Testosterone and Estradiol can prevent arteriosclerotic heart disease. ERT and HRT decreases the risk of diabetes with aging. Estradiol replacement during the first decade after menopause can delay the onset of Alzheimer's disease and dementia by ten years. If you are genetically predisposed to developing Alzheimer's or dementia by age 80, E2 replacement may postpone this onset until you turn 90. Testosterone replacement in the first 10 years after menopause postpones the onset of Alzheimer's disease and dementia for an additional ten years. Testosterone boosts immune function in both sexes and diminishes the onset and severity of infectious diseases. Aging causes cognitive decline, marked by challenges in memory and thinking, and menopause speeds up this process. Testosterone and estradiol replacement therapies may aid in reversing this decline. Muscle mass decreases after menopause due to a decline in testosterone but replacing testosterone with bio-identical pellets restores muscle mass to premenopausal levels. The latest medical article that inspired me to create this podcast was published in the journal Menopause, which discussed the challenges many women face after breast cancer treatment without hormone replacement for their severe menopausal symptoms. Here are the quotes I think you should hear: (MHT = Menopause Hormone Therapy) “Among 226 breast cancer survivors.. the menopause symptom burden was high and women's experience of menopause-related breast cancer after-care was poor. Few women felt actively involved in menopause treatment decisions. The NICE breast cancer guideline (NG101) states that women with a history of breast cancer can be offered MHT in “exceptional” circumstances if other treatments have failed (off-label use). However, NICE does not define what “exceptional” circumstances are or who gets to decide. Up to 50% of breast cancer survivors, especially those with debilitating menopausal symptoms, may choose to accept a small increase in risk in exchange for an improved quality of life and/or to mitigate future health risks associated with chronic estrogen deficiency. “Allowing”. women to have MHT only in “exceptional” circumstance undermines patient autonomy and limits a clinician's ability to integrate clinical knowledge and judgment with the best currently available evidence (which is decades behind clinical guidelines). Clinicians have a legal and ethical responsibility to patients to make informed treatment choices. If you have had breast cancer and are experiencing symptoms you no longer want to endure, my advice is to find a doctor with whom you can make an informed decision based on the latest research. It's important to understand and accept the risks and to sign a High-Risk Consent for HRT. If you aren't that brave, then seek a physician who will prescribe testosterone pellets along with vaginal estradiol to alleviate some of your post-menopausal symptoms. Life is too short to follow guidelines that are 20 years out of date when you are suffering.
This episode covers hypothyroidism in children.Written notes can be found at https://zerotofinals.com/paediatrics/endocrinology/hypothyroidism/Questions can be found at https://members.zerotofinals.com/Books can be found at https://zerotofinals.com/books/The audio in the episode was expertly edited by Harry Watchman.
This episode covers growth hormone deficiency.Written notes can be found at https://zerotofinals.com/paediatrics/endocrinology/ghdeficiency/Questions can be found at https://members.zerotofinals.com/Books can be found at https://zerotofinals.com/books/The audio in the episode was expertly edited by Harry Watchman.
This episode covers congenital adrenal hyperplasia.Written notes can be found at https://zerotofinals.com/paediatrics/endocrinology/cah/Questions can be found at https://members.zerotofinals.com/Books can be found at https://zerotofinals.com/books/The audio in the episode was expertly edited by Harry Watchman.
Dr. Yasmine Elamir joins us to address the stigmas of obesity by sharing her personal journey of overcoming Type 2 Diabesity. A triple board-certified Endocrinologist, Obesity Specialist, and Best-Selling Author with nine years of experience, Dr. Elamir compassionately guides her patients toward curing Type 2 Diabetes and achieving sustainable weight loss through her innovative app and methods. She earned her bachelor's degree from Johns Hopkins University and her medical degree from Ross University, completing her Internal Medicine residency at Robert Wood Johnson Barnabas Health and a fellowship in Endocrinology, Diabetes, and Metabolism at Mount Sinai Beth Israel, where she was Chief Fellow. As a certified Health and Wellness Coach, Dr.Elamir's mission and trajectory is to empower individuals with the knowledge and tools to heal and live free from diabesity. Dr. Yas is one of the most endearing and compassionate individuals I have ever met.Podcast Description TemplateYou can connect with Dr. Yasmine Elamir on Instagram @diabetes_md or check out her website https://linktr.ee/Dr.Yasmine
This episode covers adrenal insufficiency.Written notes can be found at https://zerotofinals.com/paediatrics/endocrinology/adrenalinsufficiency/Questions can be found at https://members.zerotofinals.com/Books can be found at https://zerotofinals.com/books/The audio in the episode was expertly edited by Harry Watchman.
This episode covers type 1 diabetes in children.Written notes can be found at https://zerotofinals.com/paediatrics/endocrinology/type1diabetes/Questions can be found at https://members.zerotofinals.com/Books can be found at https://zerotofinals.com/books/The audio in the episode was expertly edited by Harry Watchman.
Erin Fuse Brown is a professor of health services, policy, and practice at the Brown University School of Public Health and a member of the Journal's Perspective Advisory Board. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.C. Fuse Brown, O.J. Wouters, and A. Mehrotra. Partnerships between Pharmaceutical and Telehealth Companies — Increasing Access or Driving Inappropriate Prescribing? N Engl J Med 2025;392:1148-1151.
CardioNerds co-founders Dr. Daniel Ambinder and Dr. Amit Goyal are joined by Dr. Spencer Weintraub, Chief Resident of Internal Medicine at Northwell Health, Dr. Michael Albosta, third-year Internal Medicine resident at the University of Miami, and Anna Biggins, Registered Dietitian Nutritionist at the Georgia Heart Institute. Expert commentary is provided by Dr. Zahid Ahmad, Associate Professor in the Division of Endocrinology at the University of Texas Southwestern. Together, they discuss a fascinating case involving a patient with a new diagnosis of hypertriglyceridemia. Episode audio was edited by CardioNerds Intern Student Dr. Pacey Wetstein. A woman in her 30s with type 2 diabetes, HIV, and polycystic ovarian syndrome presented with one day of sharp epigastric pain, non-bloody vomiting, and a new lower extremity rash. She was diagnosed with hypertriglyceridemia-induced pancreatitis, necessitating insulin infusion and plasmapheresis. The CardioNerds discuss the pathophysiology of hypertriglyceridemia-induced pancreatitis, potential organic and iatrogenic causes, and the cardiovascular implications of triglyceride disorders. We explore differential diagnoses for cardiac and non-cardiac causes of epigastric pain, review acute and long-term management of hypertriglyceridemia, and discuss strategies for the management of the chylomicronemia syndrome, focusing on lifestyle changes and pharmacotherapy. This episode is part of a case reports series developed in collaboration with the National Lipid Association and their Lipid Scholarship Program, with mentorship from Dr. Daniel Soffer and Dr. Eugenia Gianos. US Cardiology Review is now the official journal of CardioNerds! Submit your manuscript here. CardioNerds Case Reports PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls - Hypertriglyceridemia Cardiac sarcoidosis can present with a variety of symptoms, including arrhythmias, heart block, heart failure, or sudden cardiac death. The acute management of hypertriglyceridemia-induced pancreatitis involves prompt recognition and initiation of therapy to lower triglyceride levels using either plasmapheresis or intravenous insulin infusion +/- heparin infusion. Insulin infusion is used more commonly, while plasmapheresis is preferred in pregnancy. Medications such as fibrates and omega-3 fatty acids can be used to maintain long-term triglyceride reduction to prevent the recurrence of pancreatitis, especially in patients with persistent triglyceride elevation despite lifestyle modifications. Statins can be used in patients for ASCVD reduction in patients with a 10-year ASCVD risk > 5%, age > 40 years old, and diabetes or diabetes with end-organ damage or known atherosclerosis. Consider preferential use of icosapent ethyl as an omega-3 fatty acid for triglyceride lowering if the patients fit the populations that appeared to benefit in the REDUCE IT trial. Apply targeted dietary interventions within the context of an overall healthy dietary pattern, such as a Mediterranean or DASH diet. Limit full-fat dairy, fatty meats, refined starches, added sugars, and alcohol. Encourage high-fiber vegetables, whole fruits, low-fat or fat-free dairy, plant proteins, lean poultry, and fish. Pay special attention to the cooking oils to ensure the patient is not using palm oil, coconut oil, or butter when cooking. Instead, use liquid non-tropical plant oils. Initiate a very low-fat diet (< 5% of total daily calories from fat) for 1-4 weeks when TG levels are > 750 mg/dL. Recommend and encourage patients to exercise regularly, with a minimum goal of 150 minutes/week of moderate-intensity aerobic activity. If weight loss is required, aim for more than >225 - 250 minutes/week. Develop patient-centered and multidisciplinary stra...
Are oxalates actually harming your health, or is this another nutrition myth? In this episode of Super Life, Darin Olien breaks down the real science behind oxalates, their connection to kidney stones, mineral absorption, and gut health, and whether you really need to avoid high-oxalate foods. There's a lot of fear-mongering around oxalates, but what does the latest research say? Should you stop eating spinach, beets, or almonds? What about meat's impact on kidney function? Darin pulls from peer-reviewed studies to cut through the noise and give you the facts so you can make the best choices for your health. If you've ever wondered whether oxalates are a real concern or just clickbait, this episode is a must-listen. Segment 1: What Are Oxalates? Friend or Foe? Oxalates, or oxalic acid, are naturally occurring compounds found in many plant-based foods. They serve as a defense mechanism for plants but can sometimes bind with minerals like calcium and iron in the body, potentially forming kidney stones or reducing nutrient absorption. Here's the key question: Are oxalates dangerous, or is this another health myth blown out of proportion? Here's what the research says: For most people, oxalates are NOT a problem. Your body naturally processes and eliminates excess oxalates through urine. For those prone to kidney stones, particularly calcium oxalate stones (which make up about 80% of all kidney stones), consuming too many high-oxalate foods can increase the risk. Oxalates can interfere with calcium and iron absorption, but this is only a concern for people with nutrient deficiencies. Key takeaway: If your kidneys are healthy, your body handles oxalates just fine. But if you've had kidney stones before, you might want to pay closer attention to your oxalate intake. Segment 2: What Does the Science Say About Oxalates? To cut through the noise, I pulled up the latest research from 2024 and 2025. Here's what's new: 1. Gut Microbiota Can Help Protect Against Oxalates A 2025 study in Frontiers in Nutrition found that certain gut bacteria (like Oxalobacter formigenes) actually digest oxalates, helping prevent kidney stones. Takeaway: If you're worried about oxalates, supporting your gut microbiome with probiotics might be a natural way to reduce their impact. Link: Read Study Here "The presence of oxalate-degrading bacteria in the gut can significantly lower oxalate absorption and reduce kidney stone risk." – Dr. L. Wang, NHANES Study 2. Vitamin C Supplements & Oxalate Formation Some people worry that high-dose vitamin C supplements convert into oxalates, increasing kidney stone risk. A 2025 study in Nutrients found no significant increase in urinary oxalates from vitamin C intake. Takeaway: If you take vitamin C in moderation, you don't have to worry about it increasing oxalates. Link: Read Study Here "Contrary to popular belief, moderate vitamin C supplementation does not significantly raise oxalate levels in urine." – Dr. P.C. Calder, Nutrients Journal 3. Cooking & Fermentation Can Reduce Oxalates A 2024 study on fermentation & nutrient bioavailability found that cooking reduces oxalate levels by up to 60%. Best methods? Boiling, steaming, and fermentation lower oxalates significantly. Takeaway: If you love spinach but worry about oxalates, just boil it first! Link: Read Study Here Segment 3: What About Meat? Does It Increase Kidney Stone Risk? Now, here's something you might not expect. We talk a lot about oxalates and plant-based foods, but what about meat? Could eating too much meat actually contribute to kidney stones? The research says YES—but not because of oxalates. Instead, the mechanism is uric acid and metabolic acidity. Let's break it down. 1. Red Meat & Uric Acid Stones A 2024 study in Nature Reviews Urology found that high animal protein intake increases uric acid, which contributes to kidney stones. Excess meat consumption makes urine more acidic, making it easier for stones to form. Link: Read Study Here "High animal protein intake, while providing essential amino acids, also contributes to increased acid load and uric acid production, both of which are risk factors for kidney stone development." – Dr. S. Loeb, Nature Reviews Urology 2. Meat Increases Metabolic Acidity A 2025 study from Frontiers in Endocrinology found that excessive meat consumption leads to increased acid load, calcium loss, and kidney dysfunction. This makes it harder for the kidneys to filter out waste properly. Link: Read Study Here "While meat consumption is essential for many, excessive intake can disrupt mineral ion homeostasis, increasing the risk of kidney stone disease." – Dr. R. Ahmad, Frontiers in Endocrinology Segment 4: Foods High & Low in Oxalates Knowing which foods to eat or limit is key. High-Oxalate Foods (If You're at Risk) Spinach, Swiss chard, beet greens Beets, rhubarb, sweet potatoes Almonds, peanuts, cashews Blackberries, kiwi, figs Black tea, cocoa, coffee Low-Oxalate Foods (Safer Choices) Kale, mustard greens, cabbage Cauliflower, cucumbers, zucchini Apples, bananas, melons, grapes Milk, yogurt (binds with oxalates) Eggs, fish, chicken, beef (in moderation) Segment 5: Actionable Steps to Manage Oxalate & Meat Intake If you're concerned about oxalates or meat-related kidney stones, here's what to do: Balance Oxalates with Calcium Eat calcium-rich foods with oxalates to prevent them from forming stones. Cook Your Vegetables Boiling, steaming, and fermenting reduce oxalates by up to 60%! Drink Plenty of Water Staying hydrated flushes out excess oxalates & uric acid. Don't Overdo Meat Consumption Limit red meat intake and balance with alkaline foods like vegetables & fruit. Probiotics for Gut Health Consider probiotic-rich foods like yogurt and kimchi to help break down oxalates. Final Thoughts So, should you avoid oxalates? Should you stop eating meat? Not necessarily. The real key is BALANCE. Most people don't need to avoid oxalates entirely, and meat is fine in moderation—as long as you balance it with hydration, alkaline foods, and a gut-friendly diet. What You'll Learn in This Episode: (00:00:00) Introduction – What are oxalates, and why is everyone talking about them? (00:02:15) The Truth About Oxalates & Kidney Stones – Are they really the cause? (00:05:10) How Oxalates Interact With Calcium & Iron – What the science actually says (00:08:08) Who Should Be Concerned About Oxalates? – The key factors to consider (00:11:30) The Role of Gut Health in Oxalate Absorption – How your microbiome protects you (00:14:00) Cooking vs. Raw: Does Preparation Matter? – The best ways to reduce oxalates (00:16:45) The Link Between Meat, Uric Acid & Kidney Stress – What studies are showing (00:19:30) The Best Foods for Kidney Health & Detoxing Oxalates – Practical dietary advice (00:21:00) Final Thoughts – Why balance & variety in your diet is key Don't Forget... I just launched my brand new program Superlife Supermind. Visit my website https://superlife.com/ to learn more about how you can get rid of stress, improve sleep and overall health today. Thank You to Our Sponsor: Therasage: Go to www.therasage.com and use code DARIN at checkout for 15% off Find More From Darin: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences Key Takeaway: "Oxalates aren't inherently dangerous—your gut health, kidney function, and overall diet determine how they impact your body." Bibliography – Research on Oxalates, Meat Consumption & Kidney Stones Oxalates & Kidney Stones: Wang, L., Wu, J., Jiang, Z., et al. (2025). Dietary index for gut microbiota and its protective role against kidney stones. Frontiers in Nutrition. Read Study Calder, P.C., Kreider, R.B., McKay, D.L. (2025). Enhanced Vitamin C Delivery & Oxalates. Nutrients. Read Study Zayed, A., Adly, G.M., Farag, M.A. (2025). Management of Dietary Oxalates in Foods: Metabolism & Processing. Food & Bioprocess Technology. Read Study Emmanuel, O.K., Aria, J., Jose, D. (2024). Fermentation & Nutrient Bioavailability: How Cooking Reduces Oxalates. ResearchGate. Read Study Siener, R. (2025). Tea and Kidney Stone Formation: Analyzing the Impact of Black Tea Consumption. Elsevier. Read Study Meat Consumption & Kidney Stones: Loeb, S., Borin, J.F., Venigalla, G., Narasimman, M. (2024). Plant-Based Diets and Urological Health: The Role of Animal Protein in Kidney Stone Risk. Nature Reviews Urology. Read Study Feyissa, G.D., Bidu, M.N. (2024). Dietary Determinants of Renal Stone Formation in High-Risk Populations. ResearchSquare. Read Study Ahmad, R., Sarraj, B., Razzaque, M.S. (2025). Vitamin D and Mineral Ion Homeostasis in Chronic Diseases: The Link Between Uric Acid, Meat & Kidney Function. Frontiers in Endocrinology. Read Study Sharma, S.K., Gautam, A., Bhattarai, U., Basyal, B. (2025). Environmental & Dietary Contributors to Kidney Disease: The Role of High Meat Consumption. Kidney International Reports. Read Study Sangolli, A., Nerli, R.B., Ghagane, S.C. (2024). Dietary Risk Factors & Trends in Kidney Stones: Analyzing Red Meat Intake Among Patients. Medical Science – ResearchGate. Read Study
Increased prescription of opioid medications like oxycodone and hydrocodone has led to widespread misuse of both prescription and non-prescription opioids. But did you know that opioid misuse can significantly impact the endocrine system? The Endocrine Society recently published a scientific statement titled, “Exogenous Opioids and the Human Endocrine System: An Endocrine Society Scientific Statement.” The statement reviews data on the use and misuse of opioids and discusses recent research on the endocrine-related implications of opioid use. Host Aaron Lohr talks to one of the statement’s authors, Niki Karavitaki, MD, PhD, a professor from the Institute of Metabolism and Systems Research at the University of Birmingham in the United Kingdom. Show notes are available at https://www.endocrine.org/podcast/enp98-opioids-and-the-endocrine-system — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast
Dr. Boros holds a Doctor of Medicine (M. D.) degree from the Albert Szent-Györgyi School of Medicine, Szeged, Hungary and is a retired Professor of Pediatrics, Endocrinology and Metabolism of the University of California Los Angeles (UCLA) School of Medicine. Dr. Boros is the co-inventor of the stable isotope-based dynamic metabolic profiling (SIDMAP) technology, which is a functional biochemistry tool used for detailed biochemical and deutenomics related drug testing, library screening, lead optimization and in vitro and in vivo phenotype profiling. The core technology involves studying natural and disease/drug induced variations in stable non-radiating stable 13C (carbon) and 2H (deuterium) isotope distribution patterns and cross talk among metabolites in living systems. He also established mitochondrial quantum vacuum as the prime driving force of all life related energy producing biochemical events. These occur via the quantum destabilization of hydrogen ions, i. e. protons, in structured water of mitochondrial nano-confinements that are compromised by deuterium; hence the regulation of deuterium (deutenomics, human deutenome project) is a critical process to maintain health and longevity.Dr. Boros trained as a house staff in his medical school in gastroenterology after receiving a research training fellowship from the Hungarian Academy of Sciences. Dr. Boros was a visiting Scholar at the Essen School of Medicine in Germany and also worked as a Research Scientist at the Ohio State University, Department of Surgery. Dr. Boros is the recipient of the C. Williams Hall Outstanding Publication Award from the Academy of Surgical Research of the United States (1997), the Richard E. Weitzman Memorial Research Award from the University of California (2001), the Excellence in Clinical Research Award from the General Clinical Research Center at the Harbor-UCLA Medical Center (2004) and Public Health Impact Investigator Award of the United States Food and Drug Administration (2011). Dr. Boros serves as an associate editor for the journals Springer Nature- Scientific Reports, Medicine, Pancreas, Molecules and Metabolomics.SHOWNOTES:
Alex Keuroghlian is an associate professor of psychiatry at Harvard Medical School and the director of the Division of Public and Community Psychiatry at Massachusetts General Hospital. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. D.R.A. Coelho, A.L. Chen, and A.S. Keuroghlian. Advancing Transgender Health amid Rising Policy Threats. N Engl J Med 2025;392:1041-1044.
Drs. McClung and Singer delve into common questions and clinical conundrums encountered in managing osteoporosis and fractures, including calcium use and dental procedures, in patients with osteoporosis.
Drs. Singer and McClung discuss the operationalization of a bisphosphonate “drug holiday” in people treated with this class of osteoporosis medication. They address questions regarding patient selection criteria, duration of the holiday, and strategies for determining when and with what medication treatment should be resumed.
Andrea J. Singer, MD, FACP, CCD and Michael R. McClung, MD review the preservation of bone health in perimenopausal women, with a particular focus on the role of hormone therapy and how the interplay of hormonal, lifestyle, and genetic factors is key to developing effective prevention and treatment strategies.
Use the code KETOGIRL for 20% off your order of Spirulina Here In today's episode of The Optimal Protein Podcast, we uncover a groundbreaking discovery about LEAP2, a newly identified hormone that plays a key role in hunger regulation, ketone production, and appetite suppression. We are breaking down a 2022 study published in Endocrinology titled b-Hydroxybutyrate Suppresses Hepatic Production of the Ghrelin Receptor Antagonist LEAP2 (PubMed link). This research reveals how ketones specifically b-hydroxybutyrate (BHB) interact with LEAP2 and the hunger hormone ghrelin, explaining why high-protein, low-carb, and ketogenic diets naturally reduce appetite and support fat loss. If you've ever wondered why a high-protein diet helps you stay full longer while promoting fat-burning, this episode explains the new science behind it! Key Takeaways -What is LEAP2? The newly discovered hormone that regulates hunger and ketone metabolism. -How high-protein diets generate ketones, even without high fat intake. -The role of BHB in appetite suppression. -How LEAP2 interacts with ghrelin, the hunger hormone. -Why hunger may temporarily increase when starting ketosis but decrease over time. -How this research explains the long-term appetite-suppressing effects of ketogenic and high-protein diets. Get 20% off the New 2nd Generation Tone Device HERE with the code VANESSA Visit Energybits.com (Use code KETOGIRL for 20% off your order) Follow @ketogenicgirl for updates on the latest studies and strategies to optimize protein intake and metabolic health. Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast. Link to join the facebook group for the podcast: https://www.facebook.com/groups/2017506024952802/ The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.