Podcasts about HPA

Welcome to the Ava Flanell Show, Episode 405. Today I'm going to chat with Keith Davis, The 2A Dad, and James from The 2A Boys. We'll also discuss the latest news on the HPA and SHORT Act. I'm your host, Ava Flanell. 

You can go a long way with club-level aero — and this is how to do it.On this week's episode of Tuned In, ex-Mercedes F1 aerodynamicist and brand new HPA tutor Kyle Forster helps you find big gains in performance by adding aero.

Are you really “not stressed”—or have you just gotten used to living in survival mode? In this episode of The Wellness Effect, we dive deep into the sneaky ways stress shows up in the body (spoiler: it's not just anxiety and burnout). From hair loss and hormone imbalances to stubborn belly fat and gut issues, we break down the difference between internal and external stress and how to know when your body is waving the red flag. We unpack what's really going on with your HPA axis, why minerals and nourishment matter more than you think, and why rest isn't a luxury—it's essential for healing. If you've been feeling like something's “off” but can't pinpoint why, this episode is your roadmap to uncovering the root cause.   In this episode, we discuss… What internal stress actually is (and how it mimics external stress in your body) Why cortisol isn't the villain—and how to support your adrenals for long-term resilience The real reasons so many women are undernourished (even if they're eating enough) How your environment, trauma, light exposure, and even your friendships affect your stress load What the HPA axis is and how it connects your gut, hormones, and nervous system Why you can't “out supplement” internal stress—and the foundational habits that move the needle How to start replenishing your body's “bank account” through food, sleep, nervous system support, and boundaries     Resources & Links Mentioned S02E20 - Endocrine Disruptors: 5 Hidden Toxins That Could Be Wrecking Your Hormones HTMA and GI Map testing for deeper insight into mineral and gut health 12-Week Root Cause Reset Program — DM us on our Instagrams “RESET” to join       Want more from us? Visit our website: https://www.lifestyleucoaching.ca/ Follow us on Instagram: @wellnesseffectpod Lacey Iskra - @laceeiskk Jensen - @wellnesswjensen Kira Iskra - @kiraiskk   Lifestyle U have helped over 1,000+ women transform their mind and body and become the best version of themselves. Want to be next? Click Here to Apply! - https://www.lifestyleucoaching.ca/apply If you loved this episode and want to hear more, subscribe and leave a review! Share this episode with a friend who's ready to start their own wellness journey. Follow us on Instagram at @wellnesseffectpod to stay up-to-date with the latest episodes and tips.

Ever wonder how a connecting rod that can handle 3000hp+ is designed, tested, and manufactured?  Here's a rare inside look at how true high performance aftermarket components are engineered and delivered.At the World Time Attack Challenge, Christian from Nitto Performance Engineering explains the complete workflow behind designing internal engine components like connecting rods. This includes using CMM (Coordinate Measuring Machines) to capture OEM specs, designing in Fusion 360, running FEA (Finite Element Analysis) simulations, prototyping with SLA (Stereolithography) resin 3D printing.Use ‘PODCAST75' for $75 off your first HPA course here: https://hpcdmy.co/hpa-tuned-inOnce validated, the design moves into manufacturing, using Mastercam software for CNC machining, followed by forging, nitriding, and final CMM verification.Learn why skipping motion studies or relying only on simulation data can cost you big, and how real-world validation is what separates a good part from a race-winning one. This is your inside look at doing it right the first time, using both cutting-edge software and practical track-tested experience.This is not just a tick box design process, it's about ensuring the part is right from the start and built to handle the punishing demands of the huge cylinder pressures high performance engines see.

Ben Sanderson of Gun Owners of America joins Art and War once again to discuss what in the world is going on with the HPA (Hearing Protection Act), the SHORT Act, what this has to do with a massive tax bill and much more! The lads get into it with Ben on all the new ground taking developments for gun rights in 2025, discussing what the reality on the ground is for deregulating suppressors and potentially SBR's from the NFA. The guys also ask Ben a ton of listener questions ranging from the topic of the DEA/FBI combining and absorbing the ATF's responsibilities (and why that would be awful), what traps there are if any with the HPA, what the future could look like for gun rights in relation to recent developments and much more!Check out our guest:https://www.instagram.com/realasiangunlobbyist/⁠⁠https://www.instagram.com/gunownersofamericaRAADS Autism Test:⁠⁠⁠⁠⁠https://embrace-autism.com/raads-r/⁠⁠⁠⁠⁠Check out PP.TF here:⁠⁠⁠⁠⁠⁠⁠⁠⁠https://pptaskforce.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.instagram.com/pptaskforce.est23/⁠⁠⁠⁠⁠⁠⁠⁠Check out our Patreon here to support what we do and get insider perks! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠                             ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.patreon.com/CBRNArt⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Check out our sponsors:  Cloud Defensive / Chad Defensive Rifle / EDC Lights:For 10% off site wide, that stacks with any Cloud Defensive sales, use Code: ARTANDWAR10⁠⁠⁠⁠⁠⁠⁠⁠https://clouddefensive.com⁠⁠⁠⁠⁠⁠⁠⁠Two Grunts Inc. - Quality *Ä*Ř* Manufacturer:Use code: CBRN for $50 off your order!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twogruntsinc.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Attorneys for Freedom - Attorneys on Retainer Program, sign up via this link to support the show:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://attorneysonretainer.us/artandwar⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠             ⁠⁠⁠⁠⁠⁠⁠         ⁠⁠⁠⁠⁠⁠Use code: ARTANDWAR10 for $10 off an SMU Belt at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠AWSin.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Check out our link tree for the rest of our stuff:⁠⁠⁠⁠⁠⁠https://link.space/@CBRNart⁠⁠⁠⁠⁠⁠Follow the lads on IG:     ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Nathan / Main Page: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/cbrnart/?hl=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠B.R: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/br.the.anarch⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Lucas: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/heartl1ne/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Phil: ⁠⁠https://www.instagram.com/philmxengland/

Pete Brownell of Brownells joins State of the Second to talk gun culture, DIY building, and why the firearms industry must stay politically engaged. From suppressors and the HPA to the rise of gunsmithing and trade schools, this episode is a must-listen for anyone who believes in the right to build, repair, and protect.   Register for GOALS 2025, August 9th & 10th: https://events.goa.org/goals/   Thanks to AAC Ammo & Palmetto State Armory for sponsoring our guest gear!   Special thanks to our sponsor for supporting this season! Ammo² – The smarter way to stockpile ammo, one round at a time. Start your ammo savings today!

Pete Brownell of Brownells joins State of the Second to talk gun culture, DIY building, and why the firearms industry must stay politically engaged. From suppressors and the HPA to the rise of gunsmithing and trade schools, this episode is a must-listen for anyone who believes in the right to build, repair, and protect.Register for GOALS 2025, August 9th & 10th: https://events.goa.org/goals/Thanks to AAC Ammo & Palmetto State Armory for sponsoring our guest gear!Special thanks to our sponsor for supporting this season!Ammo² – The smarter way to stockpile ammo, one round at a time. Start your ammo savings today!

What happens when you combine flame-bent titanium, 3D scanning, and a 1969 Datsun Roadster? You get one of our favourite builds, and a happy missus.Connor McElvain ‪@ConnorButter‬ from Butter Welding showcases his custom Nissan/Datsun Roadster project, where old-school cool meets new-school tools. Starting with a complete 3D scan of the body, Connor designed and built a full custom chassis using CAD, ditching the original outdated geometry for a purpose-built cantilever suspension system that was prototyped with 3D printing and finalised via CNC machining.Use ‘PODCAST75' for $75 off your first HPA course here: https://hpcdmy.co/hpa-tuned-inEvery part has been carefully modelled and refined from the Nissan SR20 VVL head to a pair of Weber carbs mounted on a one-off manifold for both form and function. A Haltech Elite 550 ECU runs the ignition and variable valve timing, blending modern control with vintage charm.The real showpiece is the titanium exhaust header, flame bent by hand and slip-fit for flexibility. This material isn't often used in this way and might not be ideal for long-term durability, but time will tell and in the meantime it looks incredible and sounds even better. This build is proof that with the right tech and dedication, you can create something pretty epic.Probably not surprising, but Connor and his roadster took the SEMA Battle of the Builders 'Young Guns' 1st place award

http://www.mofpodcast.com/http://www.pbnfamily.comhttps://www.facebook.com/matteroffactspodcast/https://www.facebook.com/groups/mofpodcastgroup/https://rumble.com/user/Mofpodcastwww.youtube.com/user/philrabhttps://www.instagram.com/mofpodcasthttps://twitter.com/themofpodcasthttps://www.cypresssurvivalist.org/Support the showMerch at: https://southerngalscrafts.myshopify.com/Shop at Amazon: http://amzn.to/2ora9riPatreon: https://www.patreon.com/mofpodcastPurchase American Insurgent by Phil Rabalais: https://amzn.to/2FvSLMLShop at MantisX: http://www.mantisx.com/ref?id=173*The views and opinions of guests do not reflect the opinions of Phil Rabalais, Andrew Bobo, Nic Emricson, or the Matter of Facts Podcast*With HPA on the horizon, Phil and Nic sit down to talk about what the silencer market might look like if they become unregulated. Afterwards, our resident hoodrat has some questions for our nerdy machinist about just how 'Bubba' one could build a spicy muffler. Matter of Facts is now live-streaming our podcast on our YouTube channel, Facebook page, and Rumble. See the links above, join in the live chat, and see the faces behind the voices. Intro and Outro Music by Phil Rabalais All rights reserved, no commercial or non-commercial use without permission of creator prepper, prep, preparedness, prepared, emergency, survival, survive, self defense, 2nd amendment, 2a, gun rights, constitution, individual rights, train like you fight, firearms training, medical training, matter of facts podcast, mof podcast, reloading, handloading, ammo, ammunition, bullets, magazines, ar-15, ak-47, cz 75, cz, cz scorpion, bugout, bugout bag, get home bag, military, tactical 

http://www.mofpodcast.com/http://www.pbnfamily.comhttps://www.facebook.com/matteroffactspodcast/https://www.facebook.com/groups/mofpodcastgroup/https://rumble.com/user/Mofpodcastwww.youtube.com/user/philrabhttps://www.instagram.com/mofpodcasthttps://twitter.com/themofpodcasthttps://www.cypresssurvivalist.org/Support the showMerch at: https://southerngalscrafts.myshopify.com/Shop at Amazon: http://amzn.to/2ora9riPatreon: https://www.patreon.com/mofpodcastPurchase American Insurgent by Phil Rabalais: https://amzn.to/2FvSLMLShop at MantisX: http://www.mantisx.com/ref?id=173*The views and opinions of guests do not reflect the opinions of Phil Rabalais, Andrew Bobo, Nic Emricson, or the Matter of Facts Podcast*With HPA on the horizon, Phil and Nic sit down to talk about what the silencer market might look like if they become unregulated. Afterwards, our resident hoodrat has some questions for our nerdy machinist about just how 'Bubba' one could build a spicy muffler. Matter of Facts is now live-streaming our podcast on our YouTube channel, Facebook page, and Rumble. See the links above, join in the live chat, and see the faces behind the voices. Intro and Outro Music by Phil Rabalais All rights reserved, no commercial or non-commercial use without permission of creator prepper, prep, preparedness, prepared, emergency, survival, survive, self defense, 2nd amendment, 2a, gun rights, constitution, individual rights, train like you fight, firearms training, medical training, matter of facts podcast, mof podcast, reloading, handloading, ammo, ammunition, bullets, magazines, ar-15, ak-47, cz 75, cz, cz scorpion, bugout, bugout bag, get home bag, military, tactical 

In this raw solo episode, I'm calling out three pieces of “wellness propaganda” I refuse to follow—sleep training, daycare before age 3, and slathering on chemical sunscreen all day.  Expect science-backed research, mom-life honesty, and feminine-first biohacks that protect our babies' nervous systems and our own hormones.  If you're a high-achieving mom who's tired of being told to override intuition for convenience, this conversation is for you. DM me the “propaganda” you're ditching on Instagram. I TALK ABOUT:  08:00 – Propaganda #1: Sleep training vs. respecting an infant's circadian rhythm and HPA-axis development 15:10 – Attachment parenting, intuitive nap cues, and why I ditched the Huckleberry tracking app 19:00 – Propaganda #2: Daycare cortisol spikes, behavioral dysregulation, and why grandparent care wins for under-threes 26:40 – Rejecting the 40-hour grind and building a feminine-flow business around motherhood 33:55 – Propaganda #3: Sunlight as a nutrient, mitochondrial biogenesis, and choosing mineral blockers over chemical SPF 40:00 – My go-to zinc sunscreens — One Skin SPF 30 (code: BIOHACKINGBRITTANY) and Think Baby SPF 30 for Callahan SPONSORS: Feel your best with NOVOS—the only supplement targeting all 12 causes of aging. Use code BIOHACKINGBRITTANY for 10% off your first month! RESOURCES: Trying to conceive? Join my Baby Steps Course to optimize your fertility with biohacking. Free gift: Download my hormone-balancing, fertility-boosting chocolate recipe. Explore my luxury retreats and wellness events for women. Shop my faves: Check out my Amazon storefront for wellness essentials. Being There: Why Prioritizing Motherhood in the First Three Years Matters LET'S CONNECT: Instagram, TikTok, Facebook Shop my favorite health products Listen on Spotify, Apple Podcasts, YouTube Music

We often chase engine and tuning upgrades first, but could a front splitter and rear wing be a smarter starting point for our race cars?We caught up with Kyle Forster from JKF Aero to break down how aerodynamics work in practice and how to make effective improvements at every level of motorsport. From the priorities of downforce vs drag, to choosing the right aero balance for your car's drivetrain layout, this conversation covers everything from tuft testing a club racer to CFD and F1-style development cycles, noting Kyle was an aerodynamicist for the Mercedes Formula 1 team during their hybrid era peak.Use ‘PODCAST75' for $75 off your first HPA course here: https://hpcdmy.co/hpa-tuned-inKyle explains key tuning strategies using splitters, wings, rake, and gurney flaps, plus the difference between 2D and 3D wing profiles and how things like swan neck mounts and dual elements can drastically improve efficiency and downforce. He also clarifies some common misconceptions about turbulent flow, stalling, and the practical implications of end plate design, big and small.Practical advice is given for grassroots racers, including the use of tufts or strong coast-down testing, and why stopwatch and driver feedback still matter. At the professional level, Kyle explains how CFD, wind tunnel testing, and track validation work together in a continuous development loop for professional motorsport including Formula 1 car development.So, where are the biggest gains to be had for a club racer? As you might have guessed, front splitters and rear wings. Get them on the car and develop over time from there, forgetting about flat floors and rear diffusers until further down the line is Kyles advice.Whether you're trying to gain lap time at your local time attack event or you're part of a pro-level development team, this video gives valuable insight into how to build aero that works. To see more of Kyle's work, check out JKF Aero at jkfaero.com or his YouTube channel ‪@KYLEENGINEERS‬.

Feeling exhausted no matter how much you rest? Wondering if adrenal fatigue, hormone imbalance, or chronic stress are wrecking your health? In this episode, Juanique sits down with Dr. Brian Rodgers to break down the hidden connections between your adrenals, thyroid, mitochondria, and overall energy — and why most doctors miss adrenal burnout completely.You'll learn exactly why adrenal recovery is key for lasting hormone balance and how functional medicine takes a different approach to healing.What You'll Learn:✔ How the HPA axis controls your stress, cortisol, and energy✔ Why your mitochondria must be fixed before adrenal recovery can work✔ How poor gut health blocks nutrient absorption and slows healing✔ The three stages of adrenal burnout — and how to tell which you're in✔ Why chronic stress, over-exercising, and stimulants can backfire✔ How functional medicine treats adrenal fatigue when conventional doctors won't✔ What CIRS (chronic inflammatory response syndrome) is — and why it shuts down healingTimestamps:00:00 — Introduction: Why adrenal health is step five in the healing process05:00 — Juanique's personal adrenal burnout journey10:00 — Understanding the HPA axis and hormone signaling15:00 — Mindset, brainwave patterns, and stress responses20:00 — Mitochondrial function: Why it comes before adrenal healing25:00 — Gut health, inflammation, and nutrient absorption30:00 — Liver detox and clearing excess cortisol35:00 — What CIRS is and how it hijacks your body40:00 — The three stages of adrenal fatigue (and why most doctors miss them)50:00 — Why stimulants, caffeine, and over-exercising make burnout worse01:00:00 — How to start rebuilding adrenal function01:05:00 — How the Gutsy Health Academy teaches you to become your own best health advocateResources & Next Steps:→ Join the Gutsy Health Academy waitlist for the next intake: https://www.mygutsyhealth.com/academywaitlist→ Book a consult or learn more about Provo Health: 801-691-1765 or provohealth.com → Follow Juanique for updates and insights: @gutsy_momSend us a text

Welcome to the podcast with Dr. Brendan McCarthy!   This episode takes you deep into the real-world practice of prescribing testosterone therapy for women. This is not a high-level overview—this is a nuts and bolts breakdown: ✅ Who it's for ✅ How it's dosed ✅ What labs to run ✅ What delivery methods are safest ✅ Why it's often done wrong—and how to get it right   With over 20 years of clinical experience, Dr. McCarthy shares the insights no seminar or textbook can offer, including the emotional and psychological challenges women face when beginning testosterone therapy, and the very real fears around side effects and community stigma.  

SHOW NOTESWhat impact does surgery have on the body?Intentional trauma Physiological response Psychosocial impact StressWhen we think about surgery, it's essential to understand that it triggers a significant reaction in the body known as the 'stress response.' This response is a complex interplay of hormonal and metabolic changes directly linked to the degree of tissue damage during surgery. It can intensify if there are any complications after the operation. Let's break it down: The whole process starts when the hypothalamic-pituitary-adrenal axis, or HPA axis, kicks into gear. This leads to a surge in hormones like cortisol, growth hormone, glucagon and catecholamines. These hormones are important because they help the body cope with stress by boosting energy availability and adjusting other bodily functions.Ebb phase (0-48hrs)Increased catabolism of stored glycogen (glycogenolysis)Suppression of insulin secretion → transient hyperglycemiaIncreased catecholamines, cortisol, and inflammatory cytokines (IL-6, TNF-α)Flow phase (3-10 days)Hypermetabolism (increased BMR)Increased protein catabolism → muscle breakdown (to provide amino acids for tissue repair and immune function)Increased lipolysis (fat breakdown) for energySustained insulin resistance → continued hyperglycemiaEnhanced GNG Pro-inflammatory response → increased cytokines and acute-phase protein productionIn the initial stages after surgery, the body releases a wave of pro-inflammatory cytokines. These cytokines jumpstart the healing process by promoting inflammation, which is important for healing surgical wounds. However, to keep this inflammation from going overboard, the body soon follows up with anti-inflammatory cytokines.These inflammatory processes have widespread effects across the body. For example, they can influence how the hypothalamus regulates body temperature or how the liver produces certain proteins that help fight infection and aid in wound healing.But here's where it gets even more interesting: other hormones like glucagon, cortisol, and adrenaline also play a role in modulating these responses. They can affect everything from your blood sugar levels to how your cardiovascular system handles the stress.So, why is all this important? Well, by understanding and managing these responses effectively, we can significantly improve how patients recover from surgery. It's all about helping the body maintain balance during a time when it's incredibly vulnerableDisruption of Metabolic Homeostasis: Surgery often disrupts the body's normal metabolic balance, notably through insulin resistance, where cells fail to respond effectively to insulin, leading to 'diabetes of the injury.' Insulin Resistance and Hyperglycemia: Insulin resistance can cause high blood sugar levels, significantly increasing the risk of surgical complications and mortality. Post-surgery, the body may enter a catabolic state, breaking down muscle instead of fat, which impairs wound healing, weakens the immune system, and reduces muscle strength. Increased Risks for Vulnerable Groups: Elderly, diabetics, and cancer patients are particularly at risk due to their compromised metabolic and inflammatory states. These groups have less physiological reserve, leading to pronounced catabolic states and increased risk of severe post-operative complications. Impact on Recovery and Outcomes: The metabolic chaos from insulin resistance to protein loss not only delays recovery but also exacerbates risks of infection and other complications. Effective management of these changes is crucial for improving surgical outcomes and ensuring that patients thrive post-surgery.ERAS helps to mitigate these by Surgery isn't just about the physical repair or removal of tissue; it triggers a cascade of stress responses in the body that can complicate recovery. These include everything from the psychological impacts of anxiety and the physiological effects of fasting to direct tissue damage and the systemic reactions to it, such as fluid shifts and hormonal imbalances.Key Components of ERAS:Comprehensive Care: ERAS isn't just a single technique but a suite of practices designed to address every aspect of the patient's journey — before, during, and after surgery. This approach aims to minimise the stress responses by controlling pain, reducing fasting times, optimising fluid management, and promoting early mobility.Minimising Fasting: One traditional practice that ERAS revises significantly is the preoperative fasting rule. Old guidelines that required fasting from midnight before surgery are now replaced with more lenient, evidence-based practices that allow intake of clear fluids up to two hours and solids up to six hours before surgery. This change helps maintain normal blood glucose levels, reduces stress, and decreases the body's shift into a catabolic (muscle-degrading) state.Nutritional Optimisation: ERAS protocols emphasise the importance of not entering surgery in a depleted state. By allowing a carbohydrate-rich drink shortly before surgery, patients are better hydrated and less anxious, which in turn reduces insulin resistance and preserves muscle mass — critical factors in speeding up recovery post-surgery. Post-operatively, oral nutrition may be delayed by the medical team until bowel function returns, typically taking close to a week. This delay is stated to reduce postoperative complications such as abdominal distension and nausea/vomiting.For the first several days post surgery fluids of limited nutritional value such as water are provided to patient until tolerance is established leading to insufficient nutrition intake during this time increasing the risk of malnutrition. The ERAS protocol promotes early oral intake within 24 hours post surgery departing from traditional fasting practices. Research suggests that between 40-50% of surgical patients have some degree of malnutrition. Pre-operative malnutrition is an independent predictor of poor post-operative outcomes. Therefore addressing malnutrition is a key component of the ERAS protocol.Immune-Enhancing Diets: Post-surgery nutrition is just as crucial. ERAS encourages diets rich in nutrients that bolster the immune system and enhance wound healing. This includes omega-3 fatty acids, which help modulate the inflammatory response; arginine, which supports protein synthesis and tissue growth; glutamine, which is vital for cellular health and recovery; and nucleotides, which are essential for rapid cell division and immune function .Immuno-nutrition is a specialised medical nutrition therapy that has been shown to adjust the body's inflammatory response: It incorporates specific nutrients like omega-3 fatty acids, arginine, polyunsaturated fatty acids, and nucleotides. It's typically recommended starting 5-7 days before surgery and continuing post-operatively for over 7 days or until oral intake meets at least 60% of the patient's nutritional requirements.How can we use this info to optimize surgical outcomes?Patient education Early nutrition pre and post surgery - Minimise fasting time What is ERAS? How does it differ from traditional care/practice?Introduced by Henrik Kehlet in 1997, the Enhanced Recovery After Surgery (ERAS) protocol has revolutionised surgical practices by optimising perioperative care. A key aspect of ERAS is its interdisciplinary approach, involving healthcare professionals from various specialties to minimise surgical stress and facilitate recovery. What is malnutrition?Malnutrition, is defined as an involuntary reduction in body weight, muscle mass and physical capabilities, affects up to 65% of surgical patients and can worsen during hospital stays. Enhancing nutritional status and promoting functional nutrition therapy is essential, even forpatients without evident malnutrition, particularly when prolonged perioperative oral intake challenges arise. Addressing malnutrition is essential for preventing surgical complications, prolongedhospital stays and higher healthcare costs. What are the benefits of ERAS for the patient?It has been shown that the key physiological benefits include:-enhances the body's anabolic processes-promotes wound healing, which is critical for patient recovery.-Reduces the risk of nutritional depletion-Minimises insulin resistance, a common issue post-surgery, allowing for better blood sugar control and improved metabolic function.-Reduce protein catabolism-And lowers the risk of pressure injuries, which can develop due to extended immobility after surgery.What are the benefits of ERAS from a healthcare perspective? From a healthcare perspective, ERAS has been shown to-shorter length of hospital stay for patients,-Lower risk of ICU transfer rates-reduce readmission rates-And all of these improvements lead to lower healthcare costs, not just for the hospital but for the overall healthcare system, as fewer complications and shorter stays reduce the financial strain.Step 1: Screen & StrengthenIf you've lost any weight unintentionally in the lead up to surgery, or been eating poorly because of a reduced appetite, you may be at risk of malnutrition and it's really important to address this prior to surgery. Research suggests that between 40-50% of surgical patients have some degree of malnutrition. Pre-operative malnutrition is an independent predictor of poor post-operative outcomes. Addressing malnutrition is a key component of the ERAS protocol and why it's effective in improving surgical outcomes for patients.Book an appointment with a dietitian who can guide you on appropriate dietary changes to minimise muscle loss, build you up and optimise nutritional status and stores pre-op. A well-nourished body tolerates surgery better, heals faster, has a stronger immune system to fight infection, and experiences fewer complications.Step 2: Consider Immunonutrition If you're planned for major surgery, especially certain cancer and abdominal surgeries, consider the use of an immunonutrition supplement in the 5-7 days pre op. These are the supplements loaded with arginine, n3s, glutamine and nucleotides to support the immune system and reduce inflammatory responses, potentially leading to fewer infections and better recovery.Step 3: Build Your Strength & Energy Stores prior to surgery Carb load with food in the days leading up to surgery - think that big bowl of pasta a footy player would have the night before the grand final. ERAS protocols have significantly reduced or eliminated long periods of "nil by mouth" (NBM) before surgery.Ask your surgical team exactly when you need to stop eating solid food – it might be much later than you think, often around 6 hours before surgery for a light meal. For clear fluids, it could be as little as 2 hours before!We'll make the most of every second to prevent unnecessary dehydration, hunger, anxiety, and preserve your body's energyStep 4: The Pre-Surgery Carb Load using clear fluidsMany ERAS protocols include a special carbohydrate-rich drink taken a few hours before surgery. Your hospital may provide this, but if they don't, we can organise orders for you or point you in the right direction.  It's usually a clear, sweet drink. Think of it as topping off your fuel tank right before the 'race'."These have been shown to reduce post-operative insulin resistance (which can slow healing), help maintain muscle strength, can reduce nausea, and improve overall wellbeing. It basically tells your body it's in a 'fed' state, not a 'starvation' state, heading into surgery.This is best done with tailor made medical nutrition drinks as they come prepped with the correct doses of maltodextrin-polymer carbs and a lower osmolality than other solutions, which essentially means they gentler on your gut and better for gastric emptying so they don't linger in your gut during surgery. Always follow surgical instructions, but ideally we're aiming for 100 grams of carbohydrate the night before surgery and about 50 grams of carbohydrate in clear fluids approximately 2 hours before anesthesia. This might look like 4 x 200ml drinks the night before, and 2 the morning of surgery If you can't access these drinks, apple or cranberry juice are reasonable replacements.  Drop us an email or message or give us a call if you'd like advice on where to get pre-op and immunonutrition supplement drinks. Then we move on to post op and Step 5 which is aiming to eat early.  ERAS encourages starting to eat and drink as soon as it's safe after surgery – often within hours, not days!As soon as your team says it's okay, try sipping water, then progress to other clear fluids, and then light foods as tolerated. Even small, frequent amounts help. This helps to stimulates your gut to start working again, reducing the risk of ileus – a slow, sleepy bowel, provides energy for healing, and can help you feel more normal, faster.If you haven't been told you can eat or drink, keep asking the question! You are your best advocate! Another tip that can help here is step 6:  Chew GumIf your team allows it, start chewing sugar-free gum several times a day once you're able. It sounds simple, but it can be surprisingly helpful in mimicking eating even when you're not allowed to, and can stimulate your digestive system to return to usual function sooner and reduce the risk of ileus.Step 7 is to Nourish to Heal This is where we bring in our good friend protein to optimise tissue repair and recovery Include protein rich food at each meal, and chat to us if you're finding this difficult because there are plenty of hacks if you're not feeling up to chicken breast and steak! And finally step 8 is to Listen to Your BodyWhile ERAS encourages early eating, we always want you to be tuned in to your body's cues and speaking up to your medical team and us if something doesn't feel right. There are plenty of interventions that can be used to keep you comfortable while still optimising your nutrition to get the best outcomes from surgery. Weimann, A., Braga, M., Carli, F., Higashiguchi, T., Hübner, M., Klek, S., et al. (2021). ESPEN practical guideline: Clinical nutrition in surgery. Clinical Nutrition, 40(7), 4745-4761.Weimann, A., Braga, M., Carli, F., Higashiguchi, T., Laviano, A., Ljungqvist, O., et al. (2017). ESPEN guideline: Clinical nutrition in surgery. Clinical Nutrition, 36(3), 623-650.Gustafsson, U. O., Scott, M. J., Schwenk, W., Demartines, N., Roulin, D., Francis, N., et al. (2019). Guidelines for perioperative care in elective colonic surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations: 2018. Clinical Nutrition, 38(2), 576-586. (Note: The ERAS® Society website, erassociety.org, is the primary source for the most current and comprehensive suite of procedure-specific guidelines.)Ljungqvist, O., Scott, M., & Fearon, K. C. (2017). Enhanced Recovery After Surgery: A review. JAMA Surgery, 152(3), 292-298.Thiele, R. H., Raghunathan, K., Brudney, C. S., Campos, S., Candiotti, K., Chaves, S., et al. (2016). American Society for Enhanced Recovery (ASER) and Perioperative Quality Initiative (POQI) joint consensus statement on perioperative fluid management in adults. Perioperative Medicine, 5, 26. (Note: This is an example of ASER/POQI consensus; look for other relevant POQI statements on specific surgical procedures and their nutritional components.)Soon, K., Levy, G. M., Cusack, L. A., Varma, S., & Nicholson, G. A. (2020). The effect of preoperative carbohydrate loading on patient outcomes in elective surgery: A systematic review and meta-analysis. Systematic Reviews, 9(1), 254.Lewis, S. J., Egger, M., Sylvester, P. A., & Thomas, S. (2001). Early enteral feeding versus "nil by mouth" after gastrointestinal surgery: systematic review and meta-analysis of controlled trials. BMJ, 323(7316), 773-776.Osland, E. J., Hossain, M. A., Khan, S., & Memon, M. A. (2014). Effect of timing of oral feeding on patient outcomes after elective colorectal surgery: A systematic review and meta-analysis. Journal of Gastrointestinal Surgery, 18(5), 1039-1051.Braga, M., Gianotti, L., Nespoli, L., Radaelli, G., & Di Carlo, V. (2002). Nutritional approach in malnourished surgical patients: a prospective randomized study. Archives of Surgery, 137(2), 174-180.Marimuthu, K., Varadhan, K. K., Ljungqvist, O., & Lobo, D. N. (2012). A meta-analysis of the effect of combinations of enhanced recovery after surgery (ERAS) interventions on postoperative outcomes. Annals of Surgery, 255(4), 640-649.

Some bearings are tough enough to survive 3000 horsepower, but that doesn't mean you should use them in your street build.Choosing the right bearing isn't as simple as just picking the toughest option and sometimes what seems like a part from 'the top shelf' can do more harm than good. In this interview, Christian from Nitto Performance Engineering breaks down some small but key differences between OEM-style bearings, ACL Race Series bearings, and coated bearings like those treated by Calico. While high-end coatings offer increased durability for extreme horsepower builds, they come with trade-offs in embeddability and long-term street reliability.Use ‘PODCAST75' for $75 off your first HPA course here: https://hpcdmy.co/hpa-tuned-inThis conversation clears up common misconceptions around bearing selection, including how coatings affect clearance, what embeddability actually does, and why some “race-spec” parts can do more harm than good in the wrong application. Christian explains that coatings like Calico are better suited to high-power engines with short service intervals, not long-life street builds.If you're chasing reliability and performance, this video will help you make an informed decision and avoid common (and expensive) bearing mistakes. Whether you're building a 3000hp drag monster or a 1000hp weekend car, it's about matching the component to your use case, not just chasing specs.

Today we get to dive into our favorite topic, joined by Rob Pincus of ICE training and Avidity Arms. We'll be discussing the fate of the HPA in congress and where we go from here in hour one. Then in hour two we'll have some calls and my thoughts, finishing up with Willie Waffle with our big Memorial Day weekend movie reviews.

Welcome to the podcast with Dr. Brendan McCarthy!   In this episode we dive deep into one of the most misunderstood and debated topics in hormone health: testosterone replacement therapy (TRT) for women. You may have heard horror stories—or glowing reviews. But what's the truth? Dr. McCarthy discusses: - Why testosterone matters for women's health - How it affects brain chemistry, mood, bone density, and even breast tissue - Its role after estrogen-suppressing breast cancer treatments - The difference between safe and unsafe TRT - What your provider should be doing to monitor and manage it effectively   Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he's been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more.   Citations: Popma, Arne, et al. "Cortisol moderates the relationship between testosterone and aggression in delinquent male adolescents." Biological psychiatry 61.3 (2007): 405-411 Likhtik, E., Stujenske, J. M., Topiwala, M. A., Harris, A. Z. & Gordon, J. A. Prefrontal entrainment of amygdala activity signals safety in learned fear and innate anxiety. Nat. Neurosci. 17, 106–113 (2014). Brannon, Skylar M., et al. "Exogenous testosterone increases sensitivity to moral norms in moral dilemma judgements." Nature Human Behaviour 3.8 (2019): 856-866.. * M.H.M. Hutschemaekers, R.A. de Kleine, M.L. Davis, M. Kampman, J.A.J. Smits, K. Roelofs,Endogenous testosterone levels are predictive of symptom reduction with exposure therapy in social anxiety disorder,Psychoneuroendocrinology,Volume 115,2020,104612 Barel, E, Abu‐Shkara, R, Colodner, R, et al. Gonadal hormones modulate the HPA‐axis and the SNS in response to psychosocial stress. J Neuro Res. 2018; 96: 1388– 1397. https://doi.org/10.1002/jnr.24259 * Buades-Rotger, M., Engelke, C., Beyer, F. et al. Endogenous testosterone is associated with lower amygdala reactivity to angry faces and reduced aggressive behavior in healthy young women. Sci Rep 6, 38538 (2016). https://doi.org/10.1038/srep38538 Ando, Sebastiano, et al. "Breast cancer: from estrogen to androgen receptor." Molecular and cellular endocrinology193.1-2 (2002): 121-128. Somboonporn, Woraluk, and Susan R. Davis. "Testosterone effects on the breast: implications for testosterone therapy for women." Endocrine reviews 25.3 (2004): 374-388. Donovitz, Gary, and Mandy Cotten. "Breast cancer incidence reduction in women treated with subcutaneous testosterone: testosterone therapy and breast cancer incidence study." European journal of breast health 17.2 (2021): 150. Glaser, Rebecca L., Anne E. York, and Constantine Dimitrakakis. "Incidence of invasive breast cancer in women treated with testosterone implants: a prospective 10-year cohort study." BMC cancer 19.1 (2019): 1271.   Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next!   Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-...   -More Links- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com

Think getting extra speed out of an aero package is just for the pros with all the money? It's not... But you DO need to know what you're doing. This week, we're sitting down with aero specialist Amir Bentatou from RS Future to discuss creating an effective aero package for your vehicle, how to actually test it, and much more.

In this episode, we welcome Amanda and Michael Drexton. Known as The Drextons, this filmmaking duo has their directorial debut, entitled Sour Party, releasing soon. Their film was the winner of the Andrews/Bernard Award, presented by Decentralized Pictures, Steven Soderbergh and Roman Coppola. In our chat, they share their backstories, pathways into filmmaking, and about the making of this project. They also talk about getting distribution — and offer practical advice for other creatives working their way up. “The Making Of” is presented by AJA:Introducing the all-new KUMO 6464-12GRedesigned for maximum reliability and performance, KUMO 6464-12G is a high-capacity 12G-SDI router featuring 64x 12G-SDI inputs and 64x 12G-SDI outputs that enables cost-effective signal routing for production and post. Ganged dual- and quad-port routing configurations let users combine multiple inputs and outputs for Dual Link video and key, 4K, UltraHD, and Quad Link 8K workflows. KUMO offers seamless routing of uncompressed, compressed, or camera raw signals. Learn more.High-Capacity Storage Meets Pro-Level DockingThe OWC Gemini delivers the best of both worlds—massive dual-drive storage and essential connectivity in one sleek Thunderbolt solution. Perfect for post-production pros, it offers RAID-ready backup, 2.5Gb Ethernet, an SD card reader, and ports for all your gear. Whether you're editing footage or offloading media, Gemini keeps your workflow fast, organized, and ready for anything. Explore it hereFeatured Event: DCS Pre-Cine Gear Kickoff PartyThursday, June 5 | 6PM - 9PM PDTJoin us as Canon hosts the Digital Cinema Society and fellow creatives from the HPA, CML, SMPTE, LACPUG, Filmmakers Alliance, PERG, and LAPPG.Enjoy great food, drinks, raffle prizes, & mingle with fellow creatives as we gear up for Cine Gear Expo 2025! Event is open to all, but confirmed RSVPs are mandatory. Free parking available…Free RSVP hereOne-Lens 360 Plates. Seamless by Design.IgelkottPlates.com offers the only plug-and-play driving and environment plates made specifically for virtual production. No stitching, no setup fuss—just clean, calibrated material designed to drop into any pipeline with zero surprises. Built for real-time workflows and in-camera results.Learn more hereNew Solutions from Videoguys:The Move 4K is the latest PTZ camera from PTZOptics, featuring auto-tracking for a more intelligent video production workflow. The Move 4K is available in 12x, 20x, or 30x zooms, and is capable of 4K at 60fps (1080p at 60fps over SDI), future-proofing your technology investment while still accommodating HD and Full HD video resolutions equipment. The Move 4K offers high performance in low-light scenarios, PoE+ capabilities, and a built-in tally light. The PTZOptics Move 4K is starting at $1,999.00 and is available at Videoguys.comExplore it hereCheck out the ZEISS Otus ML:Now on sale, the Otus ML 1.4/50mm photography lens from ZEISS is the new generation of high-quality optics for your photographic art. Find it at your favorite photo retailer!Learn more herePodcast Rewind:May 2025 - Ep. 81…“The Making Of” is created by Michael Valinsky.Promote your products or services to over 170K filmmakers, TV & broadcast production pros, and content creators reading this newsletter. Email us at mvalinsky@me.com Get full access to The Making Of at themakingof.substack.com/subscribe

Struggling to keep peptide, steroid, and amino-acid hormones straight—or how the HPA, HPT, and HPG axes actually work? In this of the Jack Westin MCAT Podcast, Mike and Molly unpack the entire endocrine system from first principles, so you're not memorizing random facts—you're learning the why behind every hormone and pathway the MCAT loves to test.

Themes: Integrative Nutrition, Intuition, Intention Episode: Do you ever feel let down by your own body? Do you wonder how you can step out of the feeling of being broken? In today's episode, Ava Nouri, an integrative and functional registered dietitian teaches us how we can trust ourselves and our bodies through the process of healing. Through her Loving Wellness® method, Ava blends science and advanced functional lab testing with intuition and intention to help clients transform into their happiest, healthiest selves. Listen to this episode to hear how you can build trust within your body for your own healing and well-being. Show Notes: - Ava's journey of dealing with her own health issues to becoming a registered dietitian  - Ava's relationship with food and how it has evolved  - Using intention rather than restriction when it comes to food - You have to care about your body, no one else will care about your body for you - Let go of perfection and embrace curiosity  - The importance of intuition in your health journey; what works for someone else might not work for you - HPA axis and its association to stressors and thyroid function - Ways to decrease the stress response and begin to trust your body - Ways to make nutrition fun Resources: - Get more from the Vital-Side Podcast here - Email podcast@vital-side.com if you're interested in being a guest or have topic ideas - Visit Ava's Website to sign up for 1:1 functional nutrition coaching programs - Ava's Instagram: @avanouriwellness - Lindsay's Instagram: @myvitalside or TikTok: @myvitalside - Visit Lindsay's Website - Click here for Lindsay's FREE Brain Retraining Guide   

We Like Shooting Episode 611 This episode of We Like Shooting is brought to you by: Midwest Industries, Swampfox Optics, XTech Tactical, Medical Gear Outfitters, Blue Alpha, Die Free Co., Bowers Group, and Matador Arms   Welcome to the We Like Shooting Show, episode 611! Our cast tonight is Jeremy Pozderac, Aaron Krieger, Nick Lynch, and me Shawn Herrin, welcome to the show! GunCon   PUBLIC EVENT - June 28th Location - Cleveland, Ohio at the Twist Drill Building (1242 E 49th St) Industry/Media Events - June 25-28 (Mixed locations around Cleveland area) https://guncon.net/event/guncon-2025/ use code wlsislife for $5 off   GOALS August 9th and 10th in Knoxville, Tennessee. https://events.goa.org/goals/ The Accountant 2 Gear Chat Nick - Pistollo 77° Vibes Pistollo 77° Shawn - AceTac Setup Made Easy AceTac setup. Aaron - Strike Carbon Fiber Suppressor Alignment  Bullet Points Shawn - Caldwell ClayCopter: Elevate Your Target Practice Experience Caldwell has introduced the ClayCopter, a new target launching device for shotgun enthusiasts, designed to shoot reusable plastic copters simulating the flight of birds. The product is expected to provide a unique shooting challenge compared to traditional clay targets, potentially influencing shooting practices and enjoyment within the gun community. The ClayCopter will be available for purchase starting April 28 at various retailers. Shawn - New MAC IX 9mm PCC Released by Military Armament Corp Military Armament Corp has launched the MAC IX, a new 9mm pistol-caliber carbine priced at $832.99, designed for shooters seeking a modern, compact firearm. Featuring AR-style ergonomics and modularity, the MAC IX is expected to appeal to the growing PCC market for competitive shooting and home defense, potentially influencing trends within the gun community. Shawn - Testing for Heavy Metals After Years of Shooting The article discusses the health risks of heavy metal exposure among shooters, particularly focusing on the case of a veteran who suffered severe lead poisoning from firearms use. It emphasizes the importance of awareness and testing for heavy metal levels, as many in the gun community may unknowingly face similar health issues. The piece highlights necessary precautions to minimize exposure and the potential long-term health impacts of lead and other heavy metals associated with shooting activities. Gun Fights Step right up for "Gun Fights," the high-octane segment hosted by Nick Lynch, where our cast members go head-to-head in a game show-style showdown! Each contestant tries to prove their gun knowledge dominance. It's a wild ride of bids, bluffs, and banter—who will come out on top? Tune in to find out! WLS is Lifestyle Silencer Central News Update Silencer Central Update https://www.youtube.com/watch?v=7H4Ri409-5I  LFD Research recreated Sig P320 Aaron's Alley NRA Takes Fight to Defend Constitutional Rights of Young Adults to U.S. Supreme Court Guns, Rights, and Eye Rolls Going Ballistic Gun Rights Win Again! We stopped the reconciliation bill over HPA and Short. Lets get it right this time. FRT Drama: Government Shenanigans! FRT lawsuit ceded by government but more fuckery afoot...by FRT? Saving Lives, Not Gun Control Despite the article being a love letter to Trump, for once, a federal law might actually save lives Irony in the Sunshine State Anti-gun republican wants to be Florida governor Missiles Over Muzzle Control! Fucking ramjet guided missle! "One Law to Rule Them All: McMahon's Magical Solution to School Safety" (no summary available) Oklahoma Takes a Stand: Brandishing Guns for Property Rights Oklahoma's new law permits individuals to brandish firearms to defend their property,

3D scanners are not always cheap, but here's why they might still be worth your money.3D scanning is changing the game for motorsport and custom fabrication, and tools like the Peel 3 scanner are bringing that capability to a more affordable level. In this interview from SEMA, we speak with Gabrielle Williams from Peel 3D/Creaform about how this tech works, where it's most useful, and what enthusiasts need to know before diving in.Use ‘PODCAST75' for $75 off your first HPA course here: https://hpcdmy.co/hpa-tuned-inThe Peel 3 offers an impressive 1.25 million measurements per second (try doing that with your tape measure!), with around 1mm of accuracy loss over 4m, plenty for reverse engineering and CAD work in automotive applications. For more precision, positioning targets (tracking dots) and scanning sprays like Magnaflux and AESUB supply help solve the usual problems with reflective or transparent surfaces.The Peel.CAD software acts as the bridge between scan data and usable CAD models, allowing users to extract entities and create features like cones, planes, and shells for use in software like Fusion 360 or Solidworks. While traditional CAD can't work directly with scan meshes, Peel.CAD simplifies this post-processing step.If you're wondering whether your system can handle it, Peel recommends a Windows 10/11 PC with at least an Intel i7, RTX 3070 GPU, and 32GB of RAM. Pricing starts around $12,300 USD including the software, putting it within reach for serious workshops and dedicated enthusiasts.

In This Hour:-- Charges on the internet say that Silencer Central worked to defeat the Hearing Protection Act, which would remove silencers from the National Firearm Act.  Silencer Central CEO Brandon Maddox addresses the claims and says his company completely backs the HPA.--  Is the dustup with Silencer Central just the latest example of internet influencers creating controversy to drive traffic to generate revenue?--  Is there a danger when loading a lever-action rifle? Could the bullet from one load hit the primer of another cartridge?Gun Talk 05.18.25 Hour 1Become a supporter of this podcast: https://www.spreaker.com/podcast/gun-talk--6185159/support.

In this episode, we dig into the controversy surrounding the stalled Hearing Protection Act, the online firestorm aimed at Silencer Central, and what it all means for hunters, shooters, and conservationists. Was this a case of corporate sabotage—or just a misunderstood push for funding wildlife through Pittman-Robertson? We take a balanced look at both sides, share personal insights as hunters, and urge listeners to step back, ask better questions, and stay grounded in truth.

We Like Shooting Episode 610 This episode of We Like Shooting is brought to you by: Brownells, Midwest Industries, Black Rhino Concealment, Gideon Optics, RMA Defense, Medical Gear Outfitters, Blue Alpha, Bowers Group, and Matador Arms   Welcome to the We Like Shooting Show, episode 610! Our cast tonight is Jeremy Pozderac, Aaron Krieger, Nick Lynch, and me Shawn Herrin, welcome to the show! GunCon PUBLIC EVENT - June 28th Location - Cleveland, Ohio at the Twist Drill Building (1242 E 49th St) Industry/Media Events - June 25-28 (Mixed locations around the Cleveland area) https://guncon.net/event/guncon-2025/ use code wlsislife for $5 off   GOALS August 9th and 10th in Knoxville, Tennessee. https://events.goa.org/goals/   - Gear Chat Shawn - ATAK: Your Ultimate Navigation Tool ATAK Shawn - Connect Without Cell Signal Meshtastic Shawn - Flux Raider News Update Flux Raider Update Ace Tac Gear Placard System Shawn - Mac 11 Rook Bullet Points Nick - PRS Match Update! PRS match update Jeremy - Wild Retraction Saga Jeremy Rost martin retraction Gun Fights Step right up for "Gun Fights," the high-octane segment hosted by Nick Lynch, where our cast members go head-to-head in a game show-style showdown! Each contestant tries to prove their gun knowledge dominance. It's a wild ride of bids, bluffs, and banter—who will come out on top? Tune in to find out! WLS is Lifestyle P320 Fun with Military Arms Military Arms Channel P320 Sig Sauer Video Aaron's Alley Going Ballistic Suppressors: Tax-Free, Please! Rep. Clyde Introduces Bill to Remove ‘Unconstitutional Taxation/Registration' of Suppressors Flawed Gun Control Study Exposed Breakdown of bad gun control study Guns Up, Government Down! Random country does pro-2a thing. Cool! California's Glock Grab: Seriously? California Democrats Push Bill That Could Ban Glock Handguns Ammo Talk: Tariffs and Tactics Podcast: What Ammo Market Data Says About Tariff Impacts So Far (ft. Black Basin Outdoors) Silencers: No Hearing Protection Needed! Silencer Shop and Silencer Central pushback on the Hearing Protection Act with lobbying groups. Alabama's New Gun Law: Triggering Tears from Gun Control Crusaders Alabama's latest gun law has drawn significant backlash from Second Amendment advocates, who argue it infringes on their rights. The law's implications for the gun community are increasingly contentious, igniting heated debates about personal freedoms versus regulation. Same Old Gun Control Nonsense Ways and Means fucks us again on the SHORT and HPA.,The speaker expresses frustration regarding the recent markup from the House Ways and Means Committee concerning the Hearing Protection Act and related legislation. Despite efforts to remove certain firearms from the National Firearms Act (NFA), key provisions, such as the removal of short-barreled rifles and shotguns, were not included, leaving the registry intact. While there are some positive changes, like reducing the tax for firearm silencers, the speaker is critical of the overall outcome and urges listeners to take action by contacting committee members to demand more substantial reforms. The speaker emphasizes the importance of public pressure and staying engaged in the legislative process, highlighting the potential for change if citizens remain active and vocal. Reviews ⭐⭐⭐⭐⭐ - from Dan Gleesach - Sandwiches are good. You are all sandwiches. Jerambe- the combo Fatty, beefy, and cheesy with the right amount of spice from the giardiniera. Sometimes, there's a sausage inside. Savage- smooth peanut butter on crustless sunbeam white bread…unsure if there is need for further explanation Nick - cold cut trio Gets the job done. Not flashy. Straight to business.

Anyone who knows modified cars will have heard of the Ring Brothers, builders of some of the greatest custom machines ever conceived. With huge scope and an equally impressive price tag, these incredible vehicles take every single piece of a build to the next level. This week, we're sitting down with the fabricator responsible for bringing these works of art to life.

Michael Sachaj and Joe Lynch discuss the people-first approach to the future of logistics. Michael is a Partner at Hyde Park Angels (HPA), a leading early-stage investor based in Chicago. About Michael Sachaj Michael Sachaj is a Partner at HPA and manages and supports HPA's investment opportunities through their lifecycle. Michael has led investment in a number of HPA's top performing investments including ShipBob, FourKites, Paccurate, and Digit. Prior to joining HPA in 2013, Michael attended Northwestern University and worked at strategy consulting firm Booz Allen Hamilton supporting various government clients in the Pentagon. Michael is an avid sneakerhead, new dad, and fluent in Polish. About HPA Hyde Park Angels (HPA) is a leading early-stage investor based in Chicago. HPA's People First model leverages world-class operating expertise, a powerful business network, and venture capital to fuel startup success. HPA's extensive network of 150+ members—comprising entrepreneurs, executives, and venture capitalists—provides strategic value to entrepreneurs by offering expertise and connections to foster growth and innovation. Key Takeaways: The People-First Approach to Funding the Future of Logistics Michael Sachaj and Joe Lynch discuss the people-first approach to the future of logistics. Michael is a Partner at Hyde Park Angels (HPA), a leading early-stage investor based in Chicago. Hyde Park Angels (HPA) is a prominent early-stage investment group based in Chicago, known for its people-first approach to investing.  Positioning HPA in a Thriving Investment Ecosystem: Chicago's early-stage funding market is more vibrant and competitive than ever, reflecting the strength and momentum of the region's innovation economy. In response, HPA is leaning into this opportunity by elevating its brand and deepening its bench of experienced investors. By combining capital with meaningful industry access and hands-on support, HPA is increasingly positioned as a partner of choice for ambitious founders. Integrating Capital with Strategic Expertise: HPA is committed to delivering more than just capital—it provides startups with access to strategic guidance from experienced investors across a wide range of industries. By thoughtfully aligning portfolio companies with members who bring relevant expertise, HPA ensures that founders receive meaningful, tailored support. This deliberate approach strengthens outcomes and reinforces HPA's role as a high-impact partner in early-stage growth. People-First Investment Philosophy: HPA stands out by prioritizing relationships over transactions. By aligning investors who bring deep operational and industry experience with entrepreneurs, HPA creates a mentorship-driven ecosystem that goes beyond capital—turning passive funding into strategic partnership. This approach builds long-term value and attracts high-quality startups. Robust Midwest Deal Flow and Ecosystem Ties: Located in Chicago, HPA leverages its geographic advantage to tap into the Midwest's growing startup ecosystem. With strong ties to local universities, accelerators, and business leaders, HPA gains early access to promising ventures often overlooked by coastal VCs, giving it a unique sourcing edge. Learn More AboutThe People-First Approach to Funding the Future of Logistics Michael Sachaj | Linkedin HPA | Linkedin HPA Paccurate Unpacking HPA's Investment in Paccurate ShipBob Digit Software  Manifest Logistics Conference The Logistics of Logistics Podcast If you enjoy the podcast, please leave a positive review, subscribe, and share it with your friends and colleagues. The Logistics of Logistics Podcast: Google, Apple, Castbox, Spotify, Stitcher, PlayerFM, Tunein, Podbean, Owltail, Libsyn, Overcast Check out The Logistics of Logistics on Youtube

You might love the look and sound of your flame-tune, but is it killing your catalytic converter (CAT)?In this interview, Matt Latino from G-Sport by GESi explains the limitations of factory catalytic converters and why performance builds often require something more capable.Use ‘PODCAST75' for $75 off your first HPA course here: https://hpcdmy.co/hpa-tuned-inG-Sport's aftermarket catalytic converters are EPA-compliant, stainless steel, and designed for high horsepower, but they're not indestructible. Matt dives into the real-world causes of CAT failures, including improper sizing, rich tuning, and aggressive launch control or anti-lag strategies. Burble, flame, and pop tunes might be fun, but they push unburnt fuel through your exhaust and straight into your catalytic converter — which can result in thermal overload or even complete failure.Like tyres on a track day, pushing your CATS too far too often will shorten their lifespan dramatically. Matt shares practical advice on how to make power in a street car while keeping your CAT alive, and what makes GESi's designs different from cheaper OEM-style ceramic core converters.Many exhaust specialists already include the likes of G-Sport CATS in their complete systems, so it's possible you might even have one and be benefiting from the performance gains.------------------------------------TIME STAMPS:0:00 - G-Sport by GESi0:22 - Limitation of Factory Catalytic Converter0:53 - Exhaust Backpressure1:06 - Aftermarket Options2:10 - Aftermarket Vs OEM Construction2:29- Why OEMs Use Ceramic2:39 - Stainless Steel Construction2:50 - Not Bulletproof3:20 - Tuning Mistakes4:00 - Everything In Moderation4:45 - Tyre Analogy5:00 - Thanks Matt!5:30 - BUILD.TUNE.DRIVE

Will carbs on V8 hotrods etc become a thing of the past when some alternatives are this easy?For those unfamiliar with ECU tuning, switching from a carburettor (carb) to EFI can seem daunting, but it doesn't have to be. The ‪@EdelbrockUSA‬ Pro-Flo 4 is designed to make the transition as simple and hassle-free as possible. With pre-calibrated sensors, a self-tuning system, and an easy-to-use app, this sequential port injection system eliminates the need for a laptop, making it one of the most user-friendly EFI solutions on the market with plug-and-play options for the Gen 3 or 4 LS, Gen 1 or 2 Ford Coyote and Chrysler Gen 3 HEMI V8's.Use ‘PODCAST75' for $75 off your first HPA course here: https://hpcdmy.co/hpa-tuned-inUnlike traditional throttle body injection (TBI) systems that mimic a carb, the Pro-Flo 4 offers true multi-point injection, improving fuel atomization, drivability, and efficiency. Injector and fuel system selection are simplified, with kits available for different power levels, and installation is made easy with a fully terminated wiring harness that requires no crimping or cutting. The distributor-based ignition system means there's no need for an additional crank trigger, further reducing complexity.The system features closed-loop control that continually learns and adapts while driving, improving fuel mapping in real-time. For those worried about fine-tuning aspects like cold starts and transient enrichment, the Edelbrock E-Tuner App provides intuitive adjustments using familiar carburetor-style terminology. This ensures that even those new to EFI can confidently dial in their setup.TIME STAMPS:0:00 - Carb to EFI0:16 - Mark Honsowetz0:22 - Edelbrock Pro-Flo 4 EFI1:09 - Self Tuning1:38 - Entry Level Tuning Option2:15 - Simple Installation2:44 - Injector Selection3:17 - Fuel System Selection3:56 - Ignition System Setup4:40 - Edelbrock E-Tuner App4:51 - No Crank Trigger5:20 - Pre-Calibrated Sensors5:40 - Aftermarket Cams6:40 - Closed Loop Control7:10 - Needs Varied Driving To Learn7:42 - Dyno Tuning8:30 - Cold Start, Transient Enrichment etc9:41 - Tuning Made Fun10:00 - Edelbrock Pricing10:27 - Batch vs Sequential Fire11:10 - Edelbrock11:21 - BUILD.T

Send us a textIn this insightful episode, host Nathan sits down with two key figures from the Heat Pump Association (HPA) – CEO Charlotte Lea and Chair Craig Dolan – to explore the role the HPA plays in the evolving UK heating landscape. They delve into the value the association brings to the industry, particularly as the nation transitions towards low-carbon heating solutions.The conversation tackles the fundamental question of whether industry associations are still necessary in today's rapidly changing world. Charlotte and Craig passionately argue for their continued relevance, highlighting their crucial function in providing a unified voice for the heat pump sector and driving positive change.A potentially contentious area is explored as Nathan raises the issue of potential conflicts of interest arising from HPA membership that may include companies also affiliated with the boiler industry and their strong advocacy for hydrogen boilers through the Heating and Hot water Council (HHIC). This leads to a nuanced discussion about navigating diverse interests within the broader heating industry.Nathan expresses his support for the HPA's proactive new strategy focused on amplifying the voices of heat pump installers – the boots on the ground who are essential to the successful rollout of this technology.The guests showcase the tangible benefits of HPA membership by highlighting the development and release of valuable industry resources, such as the new Residual Current Device (RCD) guidance and comprehensive heat pump system commissioning documents. The conversation then shifts to the complexities of the UK heating controls industry. Nathan and his guests discuss whether the competitive nature of the market might inadvertently hinder the adoption of common engineering sense and best practices in the design of energy-efficient heating systems.Finally, Charlotte and Craig shed light on the significant policy work undertaken by the HPA, including their collaborative efforts with the Department for Energy Security and Net Zero (DESNZ). They explain how the association actively engages with policymakers to shape regulations and support the widespread adoption of heat pump technology in the UK.Key Discussion Points:The core value proposition of the Heat Pump Association in the UK heating industry.The ongoing relevance and necessity of industry associations in the current climate.Navigating potential conflicts of interest with members also involved in the boiler/hydrogen fuel debate via the HHIC.The HPA's new focus on empowering and promoting the voice of heat pump installers.The importance and impact of HPA-produced technical documents, such as the new RCD guidance and commissioning documents.The challenges and opportunities within the UK heating controls industry and the potential impact of competition on best practices.The HPA's crucial policy work and collaboration with the Energy department.Support the showLearn more about heat pump heating by followingNathan on Linkedin, Twitter and BlueSky

Interview with Dr. Mike Jones, MD of Impact Minerals Ltd.Our previous interview: https://www.cruxinvestor.com/posts/impact-minerals-asxipt-developing-critical-high-purity-alumina-project-in-australia-6331Recording date: 23rd April 2025Impact Minerals has announced a transformative 50/50 joint venture to acquire Hipura Proprietary Limited, positioning the company to fast-track its entry into the high-purity alumina (HPA) market. The acquisition includes a nearly-completed pilot plant capable of producing at least 25 tons per annum of HPA, requiring just final electrical connections and approximately $500,000 in capital to commission over the next 3-6 months.The $2.2 million acquisition price is split equally between Impact and its partners, with Impact contributing $1.1 million. Both parties have also committed a further $1 million in working capital ($500,000 each) to bring the pilot plant to operational status."This acquisition significantly accelerates our path to production," said Dr. Mike Jones, Managing Director of Impact Minerals. Hipura's solvent extraction technology is similar to that used by Alpha HPA, which has achieved a billion-dollar market capitalization in the HPA space.The joint venture company, named Alluminous, will operate independently with a board structure consisting of two members from Impact, two from other shareholders, and an independent chairperson who will have the casting vote in case of disagreements.A key strategic element is the potential integration with Impact's existing Lake Hope project in Western Australia. Impact is exploring whether material from Lake Hope could serve as feedstock for the Hipura process, potentially reducing costs compared to the chemical feedstock currently required.The acquisition positions Impact as the second most advanced HPA producer in the Australian market behind Alpha HPA. "No one else in the HPA space has either got a pilot plant or can produce anywhere near that kind of quantity. We've taken a huge step forward over our peers," noted Dr. Jones.The HPA market has seen growing interest, particularly in applications for semiconductors, LED lighting, and batteries. Alpha HPA has reported indicative demand exceeding 30,000 tons for its 10,000-ton plant, suggesting strong market potential.Unlike Alpha HPA's large-scale approach requiring significant capital expenditure, Impact believes the Hipura process enables a modular approach with smaller, more capital-efficient plants that can be scaled up as demand grows.With North American investment groups involved in the joint venture, Impact is also eyeing potential geographical expansion, particularly targeting the growing semiconductor industry demand for HPA in North America.The transaction is described as "clean" with no hidden liabilities or unresolved IP issues, providing a fresh start for the technology under the new joint venture arrangement.View Impact Minerals' company profile: https://www.cruxinvestor.com/companies/impact-mineralsSign up for Crux Investor: https://cruxinvestor.com

Today's sponsor is Freed AI! Freed's AI medical scribe listens, transcribes, and writes notes for you. Over 15,000 healthcare professionals use Freed and you should too! Learn more here! Prednisone is a commonly used medication for its antiinflammatory and immunosuppressive action. On this episode I discuss prednisone pharmacology, ADRs, and much more. In the episode, I discuss how prednisone affects the HPA system in the body. Cortisol production can be greatly impacted by long term use of prednisone. GI adverse effects can be problematic with oral prednisone which is why we often give this medication with food or milk. Hyperglycemia is a complication from the use of prednisone. I've commonly seen blood sugar spike by 50-100+ mg/dL due to this medication. Osteoporosis is a long term risk with the use of prednisone. Prednisone can also impact the benefits of vaccination. I discuss this in greater depth in the drug interactions portion of the podcast.

Running IndyCars, engineering championship-winning V8 Supercars… and going carbon zero? This episode of the Tuned In podcast with performance engineer Brad Eyes takes us in some very interesting directions.

This episode FINALLY exposes how stress is silently destroying your patients' mouths!

Say goodbye to messy curly cords and more potential failure points.Steering wheel-mounted controls make it easier to adjust key functions on the fly, but getting those signals from the wheel to the car is not as simple as it sounds. Running multiple wires through a rotating steering column is unreliable, time-consuming, and they can be prone to failure due to the nature of their use. Zestek has developed a CAN-based steering wheel PCB solution (CAN hub) that simplifies installation, reduces wiring complexity, and integrates seamlessly with MoTeC ECUs, dashes, and PDMs.Use ‘PODCAST75' for $75 off your first HPA course here: https://hpcdmy.co/hpa-tuned-inWith only four wires required for full functionality (CAN high, CAN low, power, and ground), this system eliminates the need for bulky wiring looms. The pogo pin system built into the quick-release hub provides a clean and hassle-free connection, removing the need for traditional curly cords. A pre-configured DBC file is available for MoTeC users (and we're sure more in the future), while others can configure the CAN signals using a spreadsheet for quick setup.Each button and switch is fully customizable, including momentary and latching functions, as well as full-spectrum RGB LED feedback. Paddles can be used for more than just shifting, allowing functions like anti-lag, launch control, and nitrous activation. It is also sim racing compatible, making it easy to use the same wheel for both real and virtual driving while you wait out the winter weather.

In this episode, we explore the critical role of serotonin in shaping sensory maps within the brain, a process vital for interpreting sensory input and navigating the world. Serotonin, a neurotransmitter and neuromodulator synthesized from the aromatic amino acid tryptophan, influences brain development by fine-tuning sensory systems. It modulates neuronal growth, synaptic connections, and plasticity, which are essential for creating accurate sensory maps in regions like the somatosensory cortex, visual cortex, and auditory cortex. These maps serve as blueprints for processing touch, vision, and sound, with serotonin regulating the pruning of connections in the thalamus and cortex to ensure precise sensory wiring.The episode also explores the broader biological implications of serotonin, emphasizing its role in both prenatal and postnatal development. Maternally derived serotonin, supplied via the placenta from the peripheral and enteric nervous systems, significantly influences fetal brain development, affecting proliferation, differentiation, and neuronal migration in sensory regions. Postnatally, serotonin continues to support sensory integration and mood regulation, working alongside oxytocin to facilitate bonding and stress buffering. We explore environmental factors, such as stress and modern lighting, on serotonin synthesis and the hypothalamic-pituitary-adrenal (HPA) axis, which regulates cortisol release. Daylight Computer Companyuse "autism" for $25 off athttps://buy.daylightcomputer.com/RYAN03139Chroma Iight Devicesuse "autism" for 10% discount athttps://getchroma.co/?ref=autism0:00 Chroma Light Devices, use "autism" for a 10% discount03:12, Sensory Map Introduction and Serotonin's Role, The episode introduces sensory maps, neural blueprints that help the brain interpret sensory inputs like touch, vision, and sound, 04:30, Serotonin's Developmental Impact, Serotonin fine-tunes sensory systems by modulating neuronal growth, synaptic connections, and plasticity, creating precise sensory maps in the somatosensory, visual, and auditory cortices,06:04, Serotonin and Sensory Processing (Visual), Serotonin, sensory processing in the visual cortex08:29, Critical Periods and Neuroplasticity, sensory neurons and connections, pruning10:00, Brain Regions and Serotonin's Mechanisms, Serotonin, axonal guidance, neurogenesis, and migration via microtubules, brain-derived neurotrophic factor (BDNF), glutamate and GABA12:55, Serotonin and Sensory Processing (Somatosensory),13:51, Serotonin and Sensory Processing (Auditory),14:52, Stress and the HPA Axis, Cortisol, circadian rhythms and cortisol spikes, modern environments,16:16 Daylight Computer Company, use "autism" for a $25 discount20:38, Maternal Serotonin and Prenatal Influence; Postnatal Serotonin and Oxytocin; Tryptophan Metabolism and Neurodevelopment, placenta, fetal brain development, proliferation, differentiation, and neuronal migration, serotonin, oxytocin & bonding and stress buffering, TPH1 and TPH2, kynurenine pathwayX: https://x.com/rps47586Hopp: https://www.hopp.bio/fromthespectrumYT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

This week, Dr. Bikman dives deep into the metabolic role of cortisol, the body's primary glucocorticoid. He explains that while cortisol is essential for survival—mobilizing energy during fasting or stress—chronically elevated levels can wreak metabolic havoc.Cortisol is produced by the adrenal cortex under direction from the hypothalamic-pituitary-adrenal (HPA) axis. Its main role is to ensure energy availability, stimulating glycogen breakdown, muscle catabolism, and fat breakdown in specific depots. However, long-term cortisol elevation, such as in Cushing's disease, leads to fat redistribution, muscle loss, insulin resistance, and increased risk of type 2 diabetes.Cortisol's metabolic effects are driven by its action on glucocorticoid receptors inside cells, activating genes like PEPCK and glucose-6-phosphatase that stimulate gluconeogenesis and increase blood sugar. It also indirectly causes insulin resistance by increasing ceramide accumulation, which interferes with insulin signaling in cells like muscle and fat. This, combined with glucose overproduction and muscle loss (the major glucose sink), creates a perfect metabolic storm: high blood sugar, high insulin, and reduced glucose uptake.The hormone also affects fat storage patterns. Cortisol enhances fat accumulation in visceral (abdominal) fat while stimulating fat loss in subcutaneous regions like the limbs. It increases fat uptake by upregulating lipoprotein lipase and blocks fat breakdown by suppressing hormone-sensitive lipase, especially in the abdominal region. Yet cortisol alone isn't enough to cause fat gain—insulin is still required. Ben illustrates this by showing how individuals with untreated type 1 diabetes have high cortisol and high appetite but still lose fat without insulin.Lastly, cortisol influences the brain's hunger and reward systems, increasing carbohydrate cravings through neuropeptide Y and dopamine signaling. Chronic stress or medical conditions that elevate cortisol can drive overeating and central obesity. In short, while cortisol is necessary, its chronic elevation leads to insulin resistance, fat redistribution, and loss of metabolic control.Show Notes/References:For complete show notes and references, we invite you to become a Ben Bikman Insider subscriber. As a subscriber, you'll enjoy real-time, livestream Metabolic Classroom access which includes live Q&A after the lecture with Ben, ad-free podcast episodes, show notes and references, Ben's Research Reviews Podcast, and a searchable archive that includes all Metabolic Classroom episodes and Research Reviews. Learn more: https://www.benbikman.com#Cortisol #InsulinResistance #ChronicStress #GlucoseControl #MetabolicHealth #CushingsDisease #HormonalBalance #FatStorage #Ceramides #DrBenBikman #VisceralFat #FatLoss #SubcutaneousFat #BloodSugar #AppetiteRegulation #Type2Diabetes #Mitochondria #HPAaxis #CortisolAndCravings #FatDistribution

In this special live episode of the Tick Boot Camp podcast, we interview Dr. Bill Rawls, a renowned expert in chronic Lyme disease, at the ILADS conference. They dive deep into the critical steps newly diagnosed Lyme disease patients should take, discussing the complexity of chronic infections, the role of the nervous system, and key herbal-based solutions like the HPA Balance, Restore Kit, and Gut Rebuild Kit to support healing. Key Takeaways: Understanding Chronic Lyme – How multiple microbes contribute to long-term illness and why Lyme disease is more than just Borrelia. Regulating the Nervous System – The importance of managing the fight-or-flight response for improved recovery. The HPA Balance Supplement – How this formula supports HPA axis regulation, stress reduction, and immune function. The Restore Kit – A comprehensive blend of antimicrobials, adaptogens, and cellular support designed for Lyme patients. The Gut Rebuild Kit – Why gut health is essential after antibiotic use and how to restore balance with the right nutrients. Holistic Healing Approach – How emotional health, detoxification, and physiological support are all interconnected in Lyme recovery. About Dr. Bill Rawls Dr. Bill Rawls is a board-certified physician with a background in family medicine and a personal journey overcoming Lyme disease. He is the author of "Suffered Long Enough" and "Unlocking Lyme" and serves as the Medical Director of Vital Plan, an herbal supplement and wellness company. Dr. Rawls is dedicated to helping Lyme patients take control of their healing through natural solutions. Resources & Links: Follow the latest ILADS updates: ILADS.org Learn more about Dr. Bill Rawls: RawlsMD.com Stay connected with Tick Boot Camp: Website | Instagram | Facebook | YouTube | TikTok | Twitter (X)

Kris Harris kicks off season four of the Kore Kast with an episode tackling burnout recovery through the lens of cortisol regulation and strategic exercise. This episode explores why high-intensity workouts might worsen burnout while gentle movement can accelerate healing by rebalancing stress hormone patterns.• Burnout is a state of chronic stress recognized by the WHO with physical, mental, and emotional symptoms affecting 77% of professionals• Cortisol dysregulation is central to burnout – initially overproduced, then potentially becoming blunted as the HPA axis becomes exhausted• High-intensity exercise creates significant cortisol spikes that can overwhelm an already compromised stress response system• Gentle movement like walking, restorative yoga, and tai chi activates the parasympathetic nervous system and helps recalibrate cortisol rhythms• Recovery exercise should be timed strategically – mid-morning is optimal for most, avoiding workouts within three hours of bedtime• Supporting lifestyle factors include quality sleep, anti-inflammatory nutrition, mindfulness practices, social connection, and nature exposure• Common recovery mistakes include the "more-is-better" approach to exercise and exercising with a punishment mindset• Research shows moderate-intensity, time-restricted exercise programs are most effective for burnout recovery through cortisol managementThank you for joining me on this episode of the Kore Kast. If you enjoyed today's episode, I'd love for you to share it with your friends and family and, if you're feeling generous, consider donating at the link provided in the description. For more resources, visit our website at www.kore-fit.com and follow us on Instagram at korefitness_az."Transform Your Life with Kore Fitness"Kore Fitness: Your path to a healthier, stronger you. Personalized training and proven results.Disclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showhttps://www.kore-fit.com

Car brands are secretly limiting your car's potential, and it has NOTHING to do with reliability.Use ‘PODCAST75' for $75 off your first HPA course here: https://hpcdmy.co/hpa-tuned-inGetting more power out of a factory car can be surprisingly straightforward with the right software (and sometimes hardware modifications), but what goes into developing a proper tune that exploits more potential without pushing the OEM components past their limits?At SEMA, HPA had a chat with Arin Anhell from APR, one of the pioneers in the European aftermarket tuning market, to find out how they test and develop tunes, what safety measures they implement, and why modern turbocharged engines leave so much untapped potential from the factory.Also discussed:The limits of factory componentsHow APR ensures reliability in their tuningWhy OEMs leave horsepower on the tableHow direct injection affects tuning potentialThe APR Plus warranty program and what it coversIf you're considering tuning your BMW, Mini, Volkswagen, Audi, Porsche, or other VAG vehicles etc this could be a very helpful insight into some of your options from APR and sister company Dinan Engineering.TIMESTAMPS:0:00 - Getting More Power From Your Factory Car0:07 - Arin Anhell: APR0:13 - How APR Develops a Tune0:35 - Finding the Limits0:50 - Sensors & Data Collection1:19 - Dyno Testing & Power Increases1:40 - Why Do Factory Cars Have Headroom?2:23 - The Audi RS6 & Porsche Power Differences3:04 - Factory ECU Safety Margins3:39 - Fuel Quality & OEM Limitations4:07 - The MK8 GTI & Octane Impact4:42 - Oil Change Intervals & Reliability5:50 - Cylinder Pressure & Peak Torque Management6:36 - Low-Speed Pre-Ignition (LSPI)7:35 - In-Cylinder Pressure Testing8:04 - Tuning Safely Without Risk8:42 - When Factory Hardware Becomes a Limitation9:26 - Turbo Upgrades & Stage 3 Tuning9:50 - Direct Injection Fuel System Limits10:38 - APR Plus Warranty Explained11:32 - APR Engine Replacements?12:00 - ‪@APRtube‬ 12:08 - BUILD.TUNE.DRIVE

In this episode, we welcome back Kyle Elliot, a professional flat-shod Tennessee Walking Horse trainer from Shelbyville, Tennessee. The discussion primarily revolves around recent developments related to the Horse Protection Act (HPA) and its implications for the entire horse industry. Kyle shares his perspective on the HPA regulations, their history, and the broader impact on various horse breeds. The conversation highlights the challenges and confusion surrounding the enforcement of the HPA, issues about funding, scar rules, and the complexities of self-policing within the horse industry. Concerns are raised about the uncertainty this brings to smaller horse shows and the potential changes needed to adapt to future regulations. The episode also touches on the broader horse industry's need for unity in addressing these regulatory changes.00:00 Introduction and Guest Welcome00:48 Background on the Horse Protection Act (HPA)01:17 Kyle's Experience and Insights02:05 Recent Developments and Industry Impact02:40 Challenges and Confusion in the Industry03:20 Historical Context and Legal Battles05:14 Regulatory Enforcement and Industry Reactions11:17 Future Implications and Ongoing Concerns20:24 Inspection Protocols and Feasibility Issues26:24 Liability and Management Concerns38:19 Inspection Setback and Legal Challenges39:15 Confusion and Delays in Implementation40:12 USDA's Role and Public Response42:20 Concerns Over Enforcement and Fairness43:37 Potential Impact on Horse Shows44:29 Legal Authority and Inspection Procedures45:58 Scar Rule and Its Implications48:19 Future of Horse Industry Regulations01:02:05 Final Thoughts and Industry Unity

In this Brewbound interview, host Ray Latif speaks with Chris Swersey of Hop Products Australia and Steve Luke of Cloudburst Brewing to discuss the latest hop harvest, new investments in processing, and exciting beer collaborations. Chris shares insights on HPA's recent harvest, noting that yields and quality were well above average. He also highlights the company's new $35 million pellet plant, which will enhance the quality of their finished products. Steve discusses his experience brewing with HPA's Galaxy hops, particularly in the new collaboration beer "Yay Space," set to debut at the CBC. He explains how the beer blends fresh and aged lots of Galaxy, creating a balanced hazy IPA with a drier finish. With enthusiasm for the latest crop, both Chris and Steve express optimism about the future of Galaxy hops and the opportunities they create for brewers worldwide. For more information on Hop Products Australia and their latest hop innovations, visit hops.com.au. Be sure to check out Cloudburst Brewing and their latest collaboration, "Yay Space," at the Haas & HPA booth during CBC!

Episode Summary: In this episode of Your Hope-Filled Perspective, I’m joined by my friend, Pastor Jessica Van Roekel, as we talk about something so many of us are facing today—the growing challenges of stress and a work-life balance that feels anything but balanced. Together, we share from our personal stories, our professional backgrounds, and, most importantly, from a place of faith. We offer practical strategies to help you reclaim peace, set healthy boundaries, and redefine what true success looks like. My hope is that through our honest conversation, you’ll be reminded that grace and flexibility are available, and that lasting peace is found when we anchor our lives in faith. Quotables from the episode: Stress is something we all face to a greater or lesser extent. We live in a culture that promotes “If it’s going to be, it’s up to me” but if we aren’t careful to attend to appropriate stress management, prolonged stress can have a detrimental impact on our physical, emotional, mental well-being. If we go too long, for too strong, ultimately our bodies will demand we stop. So how do we work toward better work-life balance? Stress comes from a variety of places, but if we don’t learn to manage stress, it will manage us. We as women struggle with the work/life balance in a unique way because culture tells us success is gained or lost in the workplace, yet we are often the primary caregivers for our family (including everything from laundry to holiday costume sewing to permission slip signing to kissing boo-boos). In 1970, about 43 percent of women ages 16 and older were in the labor force. By 2000, 61 percent of adult women were in the labor force and that has continued through today. Arguably, today women have more on their plates than a generation ago, with less down time to rest and restore. Stress is a physiological and psychological response that occurs when we perceive a threat or challenge that EXCEEDS OUR COPING RESOURCES. This perception triggers the body's CENTRAL STRESS MGMT SYSTEM, particularly the hypothalamic-pituitary-adrenal (HPA) axis and the sympathetic nervous system (increased Heart Rate, Blood is directed to our muscles, increased alertness so you can face danger or run away) leading to the release of stress hormones like cortisol and adrenaline. Once stress passes, the HPA axis should return to normal but often doesn’t because we live life in a heightened state of stress. Our brain doesn’t know the difference between good stress and bad stress. While this natural stress response is useful for short-term danger, chronic stress keeps these hormones elevated for extended periods, which can harm both mental and physical health. Perfect balance is a myth; instead, balance is fluid and flexible. Sometimes career demands take precedence, while other times, family needs do. Extending grace to yourself and adjusting priorities based on seasons of life can prevent both guilt and burnout. The myth of “multi-tasking”—it’s physiologically impossible for your brain to multitask. Physically, chronic stress can cause headaches, muscle tension, fatigue, and a weakened immune system. It also raises the risk of heart disease, high blood pressure, digestive issues, and sleep disturbances, impacting overall physical wellness. Stress has significant effects on brain function and structure. ACUTE stress can sharpen focus and improve short-term performance by enhancing activity in brain regions like the amygdala and prefrontal cortex. However, chronic stress can have adverse effects and lead to structural changes in the brain, such as a reduction in the size of the hippocampus (affecting memory) and prefrontal cortex (affecting decision-making and executive function), while potentially increasing the size and activity of the amygdala (heightening emotional responses). Chronic stress often leads to constant worry, difficulty concentrating, and memory issues. The brain, under prolonged stress, struggles to function optimally, making it harder to focus and think clearly. Emotionally, prolonged stress can lead to feelings of irritability, anxiety, and even hopelessness and despair. It can cause mood swings and may contribute to depression, as persistent stress wears down emotional resilience. Constant connectivity has been shown to increase stress, as people may feel pressured by comparisons, notifications, and the need to stay updated. Increased academic and career pressures, societal instability, and economic uncertainty can all contribute to heightened stress. Having too much on our plate in one arena of our life leading to insufficient time and energy to devote to other areas of our life can spur stress. Consider adopting both a weekly and daily planning ritual across both your work and personal life whereby you establish the top 10 priorities for the week, then the top 3 priorities for each day, while circling the non-negotiable tasks. This narrows our focus and reduces the overwhelm of a long to-do list. When we consider that stress arises when situations exceed our coping resources and anxiety results from a fear of losing control, if we lower our expectations of others it leads to decreased stress & anxiety when things don’t measure up. Also, we often expect more from ourselves than do others. If you were to list everything you expect of yourself in a day or week, would you reasonably expect the same from others? Set Boundaries: we teach people how to treat us, and part of that is by setting and respecting boundaries. This includes learning to say “no” or “not now” gracefully and asking for help without guilt. Furthermore, appropriate boundary setting includes prioritizing non-negotiable family time, reserving specific hours for work, and protecting time for self-care. Consider Self-Care as Non-Negotiable: Redefine self-care as essential for your mental and physical health, including basics like adequate nutrition, exercise, scheduled rest breaks throughout the day, and consistent sleep-hygiene. Self-care also includes self-compassion especially on challenging days. There are no perfect days, but how we talk to ourselves on both good and challenging days matters! Pay attention to your thoughts and assess if you would talk to a friend the way you talk to yourself? Adopt a growth mindset: understanding that true success includes inner peace and joy, not just career milestones. Redefine “Success” in the Context of Balance: Never has anyone said at the end of their life that they wish they’d worked more. Consider envisioning a successful life that includes time for loved ones, mental wellness, and personal fulfillment. Return to Faith as Your Foundation: Surrender control to God and stay anchored in faith. Scripture References: Ecclesiastes 3 Matthew 11:28-30 “Come to Me, all who are weary and heavy-laden, and I will give you rest. “Take My yoke upon you and learn from Me, for I am gentle and humble in heart, and you will find rest for your souls. For My yoke is easy and My burden is light.” Isaiah 30:15 “This is what the Sovereign LORD, the Holy One of Israel, says: “Only in returning to me and resting in me will you be saved. In quietness and confidence is your strength. But you would have none of it.” Psalm 23 Recommended Resources: Reframing Rejection: How Looking Through a Different Lens Changes Everything By Jessica Van Roekel Sacred Scars: Resting in God’s Promise That Your Past Is Not Wasted by Dr. Michelle Bengtson The Hem of His Garment: Reaching Out To God When Pain Overwhelms by Dr. Michelle Bengtson, winner AWSA 2024 Golden Scroll Christian Living Book of the Year and the 2024 Christian Literary Awards Reader’s Choice Award in the Christian Living and Non-Fiction categories YouVersion 5-Day Devotional Reaching Out To God When Pain Overwhelms Today is Going to be a Good Day: 90 Promises from God to Start Your Day Off Right by Dr. Michelle Bengtson, AWSA Member of the Year, winner of the AWSA 2023 Inspirational Gift Book of the Year Award, the 2024 Christian Literary Awards Reader’s Choice Award in the Devotional category, the 2023 Christian Literary Awards Reader’s Choice Award in four categories, and the Christian Literary Awards Henri Award for Devotionals YouVersion Devotional, Today is Going to be a Good Day version 1 YouVersion Devotional, Today is Going to be a Good Day version 2 Revive & Thrive Women’s Online Conference Revive & Thrive Summit 2 Trusting God through Cancer Summit 1 Trusting God through Cancer Summit 2 Breaking Anxiety’s Grip: How to Reclaim the Peace God Promises by Dr. Michelle Bengtson, winner of the AWSA 2020 Best Christian Living Book First Place, the first place winner for the Best Christian Living Book, the 2020 Carolina Christian Writer’s Conference Contest winner for nonfiction, and winner of the 2021 Christian Literary Award’s Reader’s Choice Award in all four categories for which it was nominated (Non-Fiction Victorious Living, Christian Living Day By Day, Inspirational Breaking Free and Testimonial Justified by Grace categories.) YouVersion Bible Reading Plan for Breaking Anxiety’s Grip Breaking Anxiety’s Grip Free Study Guide Free PDF Resource: How to Fight Fearful/Anxious Thoughts and Win Hope Prevails: Insights from a Doctor’s Personal Journey Through Depression by Dr. Michelle Bengtson, winner of the Christian Literary Award Henri and Reader’s Choice Award Hope Prevails Bible Study by Dr. Michelle Bengtson, winner of the Christian Literary Award Reader’s Choice Award Free Webinar: Help for When You’re Feeling Blue Social Media Links for Host and Guest: Connect with Jessica Van Roekel: Website / Instagram / Facebook For more hope, stay connected with Dr. Bengtson at: Order Book Sacred Scars / Order Book The Hem of His Garment / Order Book Today is Going to be a Good Day / Order Book Breaking Anxiety’s Grip / Order Book Hope Prevails / Website / Blog / Facebook / Twitter (@DrMBengtson) / LinkedIn / Instagram / Pinterest / YouTube / Podcast on Apple Co-Host: Jessica Van Roekel is a worship leader, speaker, and writer who believes that through Jesus, personal histories don’t need to define the present or determine the future. She inspires, encourages, and equips others to look at life through the lenses of hope, trust, and God’s transforming grace. Jessica lives in rural Iowa surrounded by wide open spaces which remind her of God’s expansive love. She loves fun earrings, good coffee, and connecting with others. Hosted By: Dr. Michelle Bengtson Audio Technical Support: Bryce Bengtson Discover more Christian podcasts at lifeaudio.com and inquire about advertising opportunities at lifeaudio.com/contact-us.

In this episode of The Grace-Filled Leader podcast, we dive into the important distinction between burnout and HPA axis dysregulation (commonly mislabeled as adrenal fatigue). Tanya shares her personal journey and explores how chronic stress disrupts the brain-body connection, affecting leadership energy, mood, and health. Learn the symptoms of HPA axis dysfunction and how faith-based strategies, rooted in God's Word, can guide you toward healing and restoration. Discover how to protect your body, mind, and spirit while leading well.   I hope this episode blesses you! Xoxo, Tanya Episode Resources:   GFL Episode Catalog   5 Ways To Connect With Me: 1️⃣ FREE CALL: Book your FREE Coaching Call now! Get personalized and practical strategies for work-life balance. Start your grace-filled life and leadership journey ➡︎ https://gracefilledleader.com/workwithme   2️⃣ FACEBOOK: Become part of our Supportive Facebook Group. Connect, share, and learn with others navigating life and leadership ➡︎ https://gracefilledleader.com/community   3️⃣ FREE WORKSHOP: Watch my FREE “Conquer Your Email Inbox” workshop! It's your key to jumpstart productivity ➡︎ https://gracefilledleader.com/workshop   4️⃣ COACHING: Are you READY to have better Work-Life BALANCE? Are you ready to up-level your productivity and efficiency? Get on the waitlist for my NEW small group coaching program:  The Productive Leader Academy. It's the accountability and guidance you need to implement rock solid systems that will catapult your productivity! ➡︎ https://gracefilledleader.com/pla   5️⃣CONTACT: Leave me a question or comment ➡︎ https://gracefilledleader.com/contact   "Yes! Finally, a podcast helping others become the thriving leaders they're meant to be outside of hustle-culture! This is an amazing resource! Thank you so much for sharing and helping us become Spirit-driven, peaceful leaders!"    If you can relate, please consider rating and reviewing my show! It helps me reach more people – just like you – to help them change their future. Don't forget to follow the show so you don't miss any episodes! And, if you're feeling really generous, I'd be SO honored if you would share this podcast with someone.   Click here to view our privacy policy.

You're doing it all but could there be hidden mistakes hijacking your menopause fitness. Increasing protein, lifting weights, doing high intensity… How can you be this active but not working?  Disclaimer: This could trigger you. The mistakes hijacking your menopause fitness you could be doing on purpose because you were told once this is what you SHOULD DO.  This episode is for all women, and for you. So let's unpack these mistakes hijacking your menopause fitness.  Before anything.. Measure.  If you aren't measuring your body composition - skeletal muscle mass vs. body fat—you won't truly know what's working. I'll link to the 4 Smart scales in my store. You can get a Dexa or go to a gym. #1 Not Consuming Enough Fuel Women are not the same as men on carbohydrate needs. We get little, we disrupt hormones. You are influenced by cortisol, insulin, thyroid, testosterone, growth hormone and the endocrine.   How much fuel do you need? Endocrine dysfunction - ~30-35 calories per kg of FFM in women; but around 15 calories per kg FFM in men. Fat Free Mass (FFM) - say you're 130kg and you have 25% body fat. You need 2923 kcals to keep your body functioning well.   Fueling Your Workouts: Cardio: 30g carbs and 15g protein before Strength: 15g protein before + 30-45g protein after (higher in and after menopause)    Thyroid & Carbohydrates Low carb diets (under 100g) - pivotal point for lower thyroid function.  Serotonin - produced in the gut, declines with low carb diets.  Low-carb diets - don't lead to better weight loss long-term, they cause water loss.   What Happens When You're Under-Fueled?Low Energy Availability from brain (hypothalamus) to body… Hypothalamus signals HPA axis dysfunction Adrenals releases cortisol Thyroid slows metabolism Body conserves energy and breaks down muscle instead of fat for fuel   When You Fast, try one of these: High intensity intervals  Lift heavy weights  High intensity boot camp class  Reduce carbs, maintain a keto-like diet while increasing your walks   Know the Sneaky Mistakes Hijacking Your Menopause Fitness #2 Never REALLY Recovering From Hard Intervals or Hard Workouts  Some bootcamps and spin classes are rapid, high-intensity intervals without adequate recovery. Your cortisol levels during this session accumulate.  It feels like you crushed it, but here's the truth: if you're not giving yourself real recovery, you're not hitting your peak.  When you skip the full recovery, you're not building the strength and power that protect against sarcopenia (muscle loss). Try these: Warm-up A:  Run up a steep hill for 40 seconds Mark that point on the hill Slowly go back down Fully recover, with your nasal breathing. Repeat until you don't make it to the same spot on the hill Warm-up B: Run up a steep hill for 40 seconds Mark that point on the hill Quickly make your way down Cool down within 60 seconds Immediately run up again Repeat until you don't make it to the same spot on the hill They both will feel hard, but only one gets you to your maximum capacity.  The glycolytic fibers - fast twitch that sustain power fatigue quickly. Women have fewer of them than slow twitch and lose twice as fast as slow-twitch fibers. Fast-twitch fibers need power moves — like heavy lifting or box jumps — and plenty of recovery to reload and go again.  You're fooling yourself into thinking you're getting in better shape.  So test yourself… a simple protocol you can do at home. Try a full test battery you can easily do at home - I'll provide access to it in the show notes as soon as it's ready.  Measure. Monitor your waist girth, your body fat percent and your skeletal muscle. Rate your energy, sleep, focus, digestion and elimination. Are you improving, worse or the same? When you're exercising optimally these things also improve. It's not just muscle mass and fat.    Are these Mistakes Hijacking Your Menopause Fitness?   #3 Relying on Caffeine, Bar Codes and Over Emphasis on Packaged Food By nature, your cortisol level is highest at about 8am. You've fasted overnight and if you're not eating soon after waking, especially if you're exercising as a female, your body has stressor on top of stressor: Punched your ticket in midlife (less estrogen, more cortisol) Caffeine (more cortisol)  No fuel (more cortisol)  Exercise (more cortisol)  Fuel before intense exercise.  Fuel again after, especially within the 24 hour period after resistance training or other HARD workouts the need for recovery persists, so it's not just that single meal following activity. #4 Always High and Hard You have never needed high intensity more in your life than whatever age over 40 you are now.  You also need full recovery … between intervals, strength training sets and sessions.  Here's the secret: Muscle gets stronger between sessions. The exercise is the stimulus. The recovery is where fitness happens – the release of hormones, the repair and supercompensation.  Recovery time. Get AT LEAST 48 to 72 hours between hard use of the same muscle groups. Active Recovery. The low intensity movement between your hard sessions is absolutely important in increasing circulation, blood sugar stabilization, improving sleep and mood and overall fitness levels.    Keep It Simple: Movement Time. Walking at the level below where cortisol negatively spikes so you can reduce or optimize it. Short & Intense. Spend small amounts of time in high intensity interval session - where you recover completely between sessions. All Major Muscle Groups. Spend 2-3 sessions a week hitting all major muscle groups or twice to total muscle fatigue. If you're in post menopause, the volume of sets has to be greater compared to a perimenopause woman. Recover. Give yourself at least 48 hours.. 72 is often BEST.  Resources: Flipping50 Membership Flipping50 Insiders Group   Other Podcasts You Might Like: Previous Episode - Is Red Light Therapy the Answer to Aches, Pains and More Movement? Next Episode - 3 Short Strength Training Session Strategies for Women in Menopause More Like This - 12 Strength Training Mistakes in Menopause Robbing Your Results   References: Loucks AB, Verdun M, Heath EM. Low energy availability, not stress of exercise, alters LH pulsatility in exercising women. J Appl Physiol (1985). 1998 Jan;84(1):37-46. doi: 10.1152/jappl.1998.84.1.37. PMID: 9451615. https://doi.org/10.1152/jappl.1998.84.1.37 Naude CE, Brand A, Schoonees A, Nguyen KA, Chaplin M, Volmink J. Low-carbohydrate versus balanced-carbohydrate diets for reducing weight and cardiovascular risk. Cochrane Database Syst Rev. 2022 Jan 28;1(1):CD013334. doi: 10.1002/14651858.CD013334.pub2. PMID: 35088407; PMCID: PMC8795871. https://doi.org/10.1002/14651858.cd013334.pub2 Shulhai AM, Rotondo R, Petraroli M, Patianna V, Predieri B, Iughetti L, Esposito S, Street ME. The Role of Nutrition on Thyroid Function. Nutrients. 2024 Jul 31;16(15):2496. doi: 10.3390/nu16152496. PMID: 39125376; PMCID: PMC11314468. https://doi.org/10.3390/nu16152496 

Are adaptogens truly powerful, or are they just another wellness trend? In this episode of Super Life, Darin Olien dives deep into the science and history of adaptogens, breaking down what they really do for the body. From his decades of superfood hunting, Darin shares firsthand experiences discovering powerful botanicals like ashwagandha, Rhodiola, maca, and Schisandra, and how these ancient remedies are finally being recognized by modern science. He also uncovers the hidden truth about supplement quality, the best adaptogens for stress relief, and why some companies are misleading consumers with under-dosed, ineffective products. If you want to reduce stress, boost energy, and understand the REAL benefits of adaptogens, this episode is a must-listen. What Are Adaptogens? Definition: Adaptogens are compounds that enhance the body's resilience to stress and promote recovery by normalizing physiological processes, boosting energy and endurance, and protecting against cellular damage. Used in Ayurveda, Traditional Chinese Medicine, and Indigenous Healing Practices for centuries. Modern science is now validating—or challenging—these ancient uses. Scientific Evidence on Adaptogens for Stress Relief Comprehensive Benefits of Adaptogens A 2023 review confirmed the effectiveness of adaptogens in managing conditions linked to chronic stress, including anxiety, depression, fatigue, and cognitive disorders. The study highlighted commonly used adaptogens such as Rhodiola Rosea, Panax Ginseng, Eleuthero, and Ashwagandha as having significant therapeutic potential (Altanova & Korolyova, 2023).   Human Trials Show Adaptogens Can Reduce Stress A randomized, placebo-controlled trial found that adaptogenic supplements significantly improved stress resilience in 215 elite athletes. Markers such as cortisol levels, fatigue severity, and cognitive function showed measurable improvements (Hovhannisyan et al., 2017).   The Mechanism Behind Adaptogens' Effect on Stress Adaptogens regulate stress response pathways, particularly the hypothalamic-pituitary-adrenal (HPA) axis, controlling cortisol levels and stress markers like nitric oxide. This means they help maintain homeostasis and protect against both acute and chronic stress (Pawar & Shivakumar, 2012).   Effectiveness in Mental and Behavioral Disorders A systematic review on adaptogens found that Rhodiola Rosea, Eleutherococcus Senticosus, and Schisandra Chinensis all had documented effects on stress-related disorders, particularly by modulating neuroendocrine function (Panossian, 2013).   Ashwagandha and Rhodiola Specifically Target Stress and Fatigue A 2017 study reviewed the effects of Ashwagandha, Rhodiola, and Bacopa on cortisol levels and fatigue. The study concluded that these herbs significantly reduced stress-related fatigue and improved cognitive function (Ajala, 2017).   Potential Industry Bias in Adaptogen Research Some studies point out that while adaptogens have shown promise in treating stress and aging-related diseases, there is still limited large-scale human clinical data, and more rigorous studies are needed. The variability in adaptogen potency due to genetic and environmental factors complicates assessments of their true effectiveness (Panossian et al., 2020). Additionally, some adaptogen formulations are standardized by supplement companies, which raises concerns about industry influence on the research outcomes. Most Shocking Findings Adaptogens Can Mimic Stress to Build Resilience: They act as mild stress mimetics, triggering the body's adaptive stress response in small doses, similar to how a vaccine stimulates the immune system (Panossian et al., 2020). Cortisol Regulation is Key: Studies show adaptogens normalize elevated cortisol levels, preventing burnout and cognitive decline (Ajala, 2017). Elite Athletes Showed Significant Gains: Athletes taking adaptogens had a measurable improvement in reaction time, stress tolerance, and performance, suggesting real physiological benefits (Hovhannisyan et al., 2017).     Key Adaptogenic Herbs & Their Scientific Evidence 1. Ashwagandha (Withania somnifera) Study: “A Review on Adaptogenic Activity of Ashwagandha (Withania Somnifera): An Ayurvedic Appraisal” Dosage Used in Studies: 300-600 mg/day Key Findings: Ashwagandha significantly reduces cortisol levels, enhances stress resilience, and improves cognitive function (Shrilata et al., 2017). Direct Quote from Study: "Ashwagandha has been shown to significantly reduce stress-related cortisol levels and improve anxiety symptoms in clinical trials." 2. Rhodiola Rosea Study: “The Effects of Adaptogens on the Physical and Psychological Symptoms of Chronic Stress” Dosage Used in Studies: 200-600 mg/day Key Findings: Rhodiola improves mental clarity, reduces fatigue, and stabilizes stress-induced hormonal changes (Ajala, 2017). Direct Quote from Study: "Rhodiola Rosea has demonstrated significant anti-fatigue and anti-stress properties, improving cognitive function and resilience in individuals exposed to chronic stress." 3. Schisandra Chinensis Study: “Adaptogens in Mental and Behavioral Disorders” Dosage Used in Studies: 500-1500 mg/day Key Findings: Schisandra enhances adrenal function, improves focus, and has neuroprotective effects(Panossian, 2013). Direct Quote from Study: "Schisandra has adaptogenic effects that enhance cognitive performance, improve stress resilience, and protect the nervous system from oxidative stress." 4. Maca Root (Lepidium meyenii) Study: “Effects of Adaptogens on the Central Nervous System” Dosage Used in Studies: 1500-3000 mg/day Key Findings: Maca supports energy levels, hormonal balance, and mood stability (Panossian & Wikman, 2010). Direct Quote from Study: "Maca root exhibits adaptogenic activity, particularly in enhancing physical stamina and resilience against psychological stress."     Shocking Research Insights Adaptogens Mimic Stress to Build Resilience Some researchers describe adaptogens as “mild stress mimetics”, triggering small stress responses that strengthen the body's ability to handle major stressors (Panossian et al., 2020). Clinical Trials on Elite Athletes Prove Effectiveness A randomized controlled trial on 215 elite athletes found that adaptogens significantly improved stress tolerance, reduced cortisol, and enhanced reaction time (Hovhannisyan et al., 2017). Industry Bias: Are Adaptogens Overhyped? Some studies highlight a lack of large-scale, independent research and potential conflicts of interest in studies funded by supplement companies (Panossian et al., 2020). Final Thoughts: Science or Pseudoscience? Science-Backed Benefits Exist: Studies show adaptogens modulate stress response systems, reduce fatigue, and improve mental performance. More Human Trials Needed: Many studies rely on animal models or small-scale trials. The lack of large-scale, independent clinical trials leaves some uncertainty. Potential Industry Bias: While there is strong evidence for adaptogens, commercial interests may be influencing research directions and outcomes.     What You'll Learn in This Episode: (00:00:00) Introduction – The growing hype around adaptogens: real or marketing? (00:02:15) The Power of Plants & Adaptogenic Herbs – Why ancient cultures relied on them for thousands of years. (00:04:19) Are Adaptogens Actually Stress Relievers? – What the research says about their effects. (00:06:21) How Stress Affects the Body – The connection between modern lifestyle and chronic stress. (00:07:05) The Science of Adaptogens & Stress Response – How they regulate the nervous system. (00:09:09) The Best Research-Backed Adaptogens – Ashwagandha, Rhodiola, ginseng, and more. (00:11:32) Why Your Supplement Might Be Useless – The industry's biggest problem: poor quality. (00:13:45) Adaptogens & Athletic Performance – What studies show about energy, stamina, and recovery. (00:16:20) The Problem with Western Medicine Ignoring Adaptogens – Why ancient wisdom is finally being validated. (00:19:18) The Best Way to Take Adaptogens – Should you use tinctures, powders, or capsules? (00:21:10) How to Find High-Quality Adaptogens – What to look for in supplement brands. (00:23:40) Final Thoughts & How to Use Adaptogens Daily – The best way to integrate them into your routine.     Thank You to Our Sponsors: Therasage: Go to www.therasage.com and use code DARIN at checkout for 15% off Fatty15: Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/DARIN and using code DARIN at checkout.     Find More From Darin: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences     Key Takeaway: "Adaptogens aren't a quick fix—but used correctly, they can be one of the most powerful tools for long-term resilience, energy, and stress management."     Bibliography: Altanova & Korolyova, 2023 – Review on adaptogens in stress-induced conditions. Hovhannisyan et al., 2017 – Adaptogens improve athletic performance and stress tolerance. Ajala, 2017 – Effects of Ashwagandha, Rhodiola, and Bacopa on stress markers. Panossian, 2013 – Adaptogens for mental health. Panossian & Wikman, 2010 – Neurological effects of adaptogens.