Podcasts about Karolinska Institute

On this episode Lara and Vyanka talk to Professor Petter Brodin from the Karolinska Institute all about understanding variation in human immune systems and how immune networks function in health and disease. This is ImmunoTea: Your Immunology Podcast, presented by Dr Lara Dungan and Dr Vyanka Redenbaugh. This is the show where we tell you all about the most exciting research going on in the world of immunology. So grab a cup of tea, sit down and relax and we'll fill you in. Contact us at ImmunoTeaPodcast@gmail.com or @ImmunoTea on twitter. Hosted on Acast. See acast.com/privacy for more information.

Trump pulls his surgeon general pick Dr. Casey Means after GOP resistance led by Senator Bill Cassidy stalls her nomination. Maine Governor Janet Mills drops out of the Democratic Senate primary, clearing the path for progressive candidate Graham Platner to take on Republican Susan Collins. Three members of the same family are indicted on federal charges for allegedly assaulting a Turning Point USA reporter during an anti-ICE protest in Minneapolis. A new study suggests higher consumption of unprocessed meat may reduce Alzheimer's risk for people carrying the APOE4 gene, raising questions about personalized nutrition - researchers behind the study Dr. Sara Garcia-Ptacek and Dr. Jakob Norgren of the Karolinska Institute weigh in.      Pure Talk: Dial #250 and say keyword MEGYN KELLY to switch to Pure Talk and get unlimited data for just $34.99 a month!   Herald Group: Learn more at https://GuardYourCard.com Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

A blockbuster MS drug undergoes FDA re-evaluation. We explore the story of Ocrelizumab, a treatment for primary progressive multiple sclerosis, following a patient petition that highlighted internal disagreements among agency reviewers regarding its efficacy. We look to Sweden, where new research involving sibling pairs separated by adoption investigates how early-life environments shape long-term health and social outcomes. Finally, we revisit the dominant medical narrative on Alzheimer's disease. Why is it so difficult to move towards comprehensive treatments? Has the focus on amyloid plaques hindered our understanding of other critical factors like vascular health and social inequality? Peter Doshi is a senior editor at The BMJ and an associate professor of pharmaceutical health services research at the University of Maryland. Erik Peterson is an associate professor at the Karolinska Institute in Stockholm, specializing in psychiatric epidemiology and adoption studies. Carol Brayne is a professor emerita of public health medicine at the University of Cambridge and a leading expert in the epidemiology of dementia. Reading List: Multiple sclerosis: Could Roche's bestselling drug Ocrevus be doing more harm than good in women with primary progressive MS? Home environment conditions during childhood and psychosocial outcomes across three generations in Sweden: population based adoption-discordant sibling comparison study  

This new episode of Let's Talk Cancer, Cary Adams speaks with Dr Jackson Orem of the Uganda Cancer Institute (UCI), a UICC member, about a key driver of equity in cancer care: improving access to oncology medicines in low-resource settings.Together they explore the current landscape of cancer care in Uganda and the wider region, what it takes to strengthen cancer services sustainably, and how collaborative partnerships such as UICC-led Access to Oncology Medicines (ATOM) Coalition are supporting countries to build the systems, skills, and financing needed for reliable access to quality-assured oncology medicines and diagnostics, to ensure that essential medicines and diagnostics reach the right people and the right time – safely, affordably, and consistently.Dr Orem is a medical oncologist trained at Makerere University and the Karolinska Institute, and he has led the Institute's expansion in cancer treatment, research, and international partnerships, contributing significantly to cancer care in Uganda and across Africa. Hosted on Acast. See acast.com/privacy for more information.

Emotion Regulation Individual Therapy for Adolescents (ERITA) and its internet-delivered version (IERITA) is just one of a couple of treatments developed specifically to address nonsuicidal self-injury (NSSI) among adolescents. In this episode, Dr. Johan Bjureberg from the Karolinska Institute in Stockholm, Sweden walks us through in detail each of the 11 sessions of IERITA and IERITA's 6 parallel sessions for parents. Learn more about Dr. Bjureberg's work here, and follow his research lab and their projects and publications at Emotion regulation, Self-injury, Suicide, and Intervention (ESSI) here. Below are links to his research on ERITA/IERITA referenced in this episode: Bjureberg, J., Ojala, O., Hesser, H., Häbel, H., Sahlin, H., Gratz, K. L., Tull, M. T., Knutsson, E. C., Hedman-Lagerlöf, E., Ljótsson, B., & Hellner, C. (2023). Effect of internet-delivered Emotion Regulation Individual Therapy for Adolescents with Nonsuicidal Self-Injury Disorder: A randomized clinical trial. JAMA Network Open, 6(7), e2322069. Bjureberg, J., Sahlin, H., Hedman-Lagerlof, E., Gratz, K. L., Tull, M. T., Jokinen, J., Hellner, C., & Ljotsson, B. (2018). Extending research on emotion regulation individual therapy for adolescents (ERITA) with nonsuicidal self-injury disorder: Open pilot trial and mediation analysis of a novel online version. BMC Psychiatry, 18, 326. Bjureberg, J., Sahlin, H., Hellner, C., Hedman-Lagerlof, E., Gratz, K. L., Bjarehed, J., Jokinen, J., Tull, M. T., & Ljotsson, B. (2017). Emotion regulation individual therapy for adolescents with nonsuicidal self-injury disorder: A feasibility study. BMC Psychiatry, 17, 411. Follow Dr. Westers on Instagram and Twitter (@DocWesters). To join ISSS, visit itriples.org and follow ISSS on Facebook and Twitter (@ITripleS). The Psychology of Self-Injury podcast has been rated #5 by Feedspot in their "Best 20 Clinical Psychology Podcasts" and by Welp Magazine in their "20 Best Injury Podcasts."

With Elena Raffetti, Karolinska Institute, Stockholm - Sweden and Mayank Dalakoti, University of Cambridge, Cambridge - UK. Link to European Heart Journal paper Link to European Heart Journal editorial

There are advances being made in the area of dementia and cognitive ageing. But sometimes it feels like a race against time, so what can the latest research reveal?Evidence-based solutions may help to foster better coordination between health and social care systems across the Europe. Our three guests, whose projects benefited from EU research and innovation funding, are helping to make a complex picture, clearer.Alina Solomon is professor of Neuroepidemiology at the University of Eastern Finland, visiting professor at Imperial College London, and senior researcher at the Karolinska Institute. She is particularly interested in dementia risk detection and therapeutic approaches for dementia risk reduction.Julia Neitzel is assistant professor at the Department of Radiology and Nuclear Medicine at the Erasmus University Medical Centre in Rotterdam, the Netherlands. Neitzel uses brain scans in large population studies to discover what protects and hurts brain health.Currently professor at the University of Luxembourg, Anja Leist will soon be taking up a professorship at the University of Heidelberg. Her research focuses on sex and gender differences, socio-economic inequalities, and risk reduction in cognitive ageing and dementia.

Women are less likely to receive a diagnosis for autism during their childhood. That's according to new research led by the Karolinska Institute in Sweden scrutinised the diagnosis rates of autism between 1985 and 2020. To discuss the findings of the research Anton spoke to Eleanor McSherry, Former head of Autism Studies at University College Cork and Neurodiversity Expert.

Women are less likely to receive a diagnosis for autism during their childhood. That's according to new research led by the Karolinska Institute in Sweden scrutinised the diagnosis rates of autism between 1985 and 2020. To discuss the findings of the research Anton spoke to Eleanor McSherry, Former head of Autism Studies at University College Cork and Neurodiversity Expert.

Synopsis: Fresh from the JPM 2026 in San Francisco, Alok Tayi welcomes Johan Luthman, Executive Vice President of R&D at Lundbeck, for a sweeping, deeply personal conversation on the future of neuroscience drug development. From his early days as a Swedish clinician-scientist to leading breakthrough Alzheimer's programs and rebuilding Lundbeck's pipeline from the ground up, Johan shares the pivotal moments—and phone calls—that shaped a 30-year career across AstraZeneca, Merck, Serono, and now Denmark's neuroscience powerhouse. The discussion dives into Lundbeck's bold strategic reset: letting biology lead, de-risking early in patients, embracing rare disease and sleep medicine, and making disciplined bets on monoclonal antibodies, migraine prevention, epilepsy, and neuroendocrine disorders. Johan explains how the company shifted capital toward innovation, rebuilt its portfolio through targeted acquisitions, and built one of the most advanced neuroscience pipelines in pharma today. In one of the episode's most powerful moments, Johan opens up about his personal motivation—caring for family members with Alzheimer's and dedicating his career to diseases of the brain. From AI-driven R&D productivity and adaptive trials to Denmark's unique foundation-owned pharma model, this conversation is a masterclass in scientific rigor, decision-making under uncertainty, and keeping patients at the center of everything. Biography: In 1991, Johan Luthman began his career in the pharmaceutical industry in Astra, later AstraZeneca. In 2005, Johan joined Serono as Head of Neuroscience & Immunology Research, and subsequently, in MerckSerono, as Therapy Area Head, Neurology & Immunology. In 2009, he became CEO of biotech start-up GeNeuro. In late 2009, Johan joined Merck as VP & Franchise Integrator for Neuroscience and Ophthalmology. In 2014, he came to Eisai where he was Senior Vice President and Head of Clinical Development. Johan joined Lundbeck as Executive Vice President, R&D in March 2019. Johan is a Swedish national and is trained as a Doctor of Dental Sciences from the Karolinska Institute, Sweden. He also holds a PhD in Neurobiology and Histology as well as an Associate Professor title from the Karolinska Institute, Sweden. Johan is a Member of the Board of Directors of Brain+.

Creatine is now one of the most widely used and well-researched supplements in elite sport — but few people know the story of how it first made its way into Olympic performance programmes. In this episode of the Science for Sport Podcast, Richard Graves sits down with Steven Jennings, one of the key figures behind the early adoption of creatine in elite sport, to unpack a remarkable story that begins long before creatine was common knowledge. Steven takes us back to the early 1990s — a pre-internet era where sports nutrition research travelled slowly, secrecy mattered, and a single kilogram of creatine played a role in reshaping performance preparation ahead of the Barcelona 1992 Olympic Games. From working directly with pioneering researchers at the Karolinska Institute to navigating Olympic-level scrutiny, this is a rare, first-hand account of how science moved from the lab to the field. Beyond performance sport, the conversation also looks forward. Steven shares why he believes we are only just beginning to understand creatine's wider potential — from cognition and ageing to plant-based diets and long-term health. This is an essential listen for practitioners who want to understand not just what works in performance nutrition, but how evidence, trust, regulation, and timing shape real-world impact. In this episode you will learn * What creatine actually is and how it works at a cellular level * How early research in the early 1990s changed elite sport preparation * Steven's role in bringing creatine into Olympic sport ahead of Barcelona 1992 * Why creatine was (and still is) legal, safe, and fundamentally different from banned substances * How creatine became associated with repeated high-intensity performance and recovery * Why creatine research is now expanding beyond sport into cognition, ageing, and health * Why we may still be “scratching the surface” of creatine's full potential About Steven Jennings Steven Jennings is a sports nutrition entrepreneur and former professional cyclist who played a pivotal role in the early commercialisation of creatine for elite sport. In the early 1990s, he worked directly with leading researchers from the Karolinska Institute to help translate groundbreaking creatine research into real-world Olympic performance programmes. Over the past three decades, Steven has remained closely connected to the evolution of creatine research, from elite performance applications to emerging work in health, cognition, and ageing. Today, he continues to focus on education, innovation, and the future direction of creatine science. FREE 7d SCIENCE FOR SPORT ACADEMY TRIAL SIGN UP NOW: https://bit.ly/SFSepisode241 ​ Learn Quicker & More Effectively ​ Optimise Your Athletes' Recovery ​ Position Yourself As An Expert To Your Athletes And Naturally Improve Buy-In ​ Reduce Your Athletes' Injury Ratese ​ Save 100's Of Dollars A Year That Would Otherwise Be Spent On Books, Courses And More ​ Improve Your Athletes' Performance ​ Advance Forward In Your Career, Allowing You To Earn More Money And Work With Elite-Level Athletes ​ Save Yourself The Stress & Worry Of Constantly Trying To Stay Up-To-Date With Sports Science Research

Per Palmgren is Associate Professor in Medical Education at Karolinska Institute in Stockholm, Sweden where he is the director of doctoral studies at the Department of Learning, Informatics, Management and Ethics. In addition to his work as an academic, Per is an award-winning ballroom dancer who has represented his country many times. He also teaches and adjudicates in dance competitions. In this conversation we explore these different instances of performing. https://ki.se/en/people/per-palmgren

This year's Nobel Prize in Physiology or Medicine has been awarded for discoveries that explain how the immune system attacks hostile infections, but not the body's own cells. We explain the science that won Japan's Shimon Sakaguchi and US researchers Mary Brunkow and Fred Ramsdell the prestigious award.How robots can help children with reading anxiety. Lauren Wright from the University of Chicago who led this research explains.A new targeted antibiotic has been found that treats Inflammatory Bowel Disease. Dr Graham Easton who is Professor of Clinical Communication Skills at Queen Mary University of London describes how it works.Missing your first mammogram appointment has as much impact on breast cancer outcomes than an inherited genetic risk according to new research. Ziyan Ma from the Department of Medical Epidemiology and Biostatistics at the Karolinska Institute tells us more.And should we reconsider how we treat blood pressure? Presenter: Claudia Hammond Producer: Katie Tomsett

Vidcast: https://www.instagram.com/p/DOwbtF0jPOI/Pregnancy is a blessed event, but it is accompanied by discomfort and, at times, outright pain.  The golden rule during these 9 months is to avoid all but absolutely necessary medications. Over the years, the pain and fever medication of choice has been acetaminophen, better known as the brand Tylenol.Now, some government officials are warning that acetaminophen during pregnancy might be linked to the later development of neurodevelopmental disorders including autism and autism spectrum disorders.  Let's review what we do know about this issue.In 2024, epidemiologists, neonatologists, and obstetrician-gynecologists at Sweden's famed Karolinska Institute published a study of nearly 2.5 million Swedish mothers, children and their siblings in the Journal of the American Medical Association or JAMA.  It failed to show any statistically significant increased risk for autism, ADHD-hyperactivity, or intellectual disability associated with acetaminophen use during pregnancy once familial-genetic and shared environmental factors were properly factored. This year, public health researchers from New York's Mount Sinai Medical Center, the University of Southern California, The University of Massachusetts, and Harvard's School of Public Health published their meta-analysis of 26 studies of more than 3.4 million mother-child pairs across North America, Europe, and Asia.They concluded that the evidence was “suggestive but not sufficient to infer causality” between acetaminophen use during pregnancy and later neurodevelopmental disorders.  Potential study shortcomings included:  data regarding maternal drug use relied upon recall; there was data heterogeneity across studies; and there were numerous potential confounding factors.The investigators advise that pregnant women could continue to use acetaminophen if needed, but at the lowest effective dose and for the shortest necessary duration.  They did not recommend complete avoidance of the medication.The bottom line is that acetaminophen, Tylenol, continues to be recommended as the first-line medication for pain and fever during pregnancy in guidelines from the American College of Obstetricians and Gynecologists, Britain's Royal College of Obstetricians and Gynecologists, and other medical organizations.  These organizations warn against the use of ibuprofen, naproxen and other nonsteroidal anti-inflammatory drugs as their use has been associated with birth defects.Clinicians continue to emphasize the need to treat fevers during pregnancy.  Failure to do so increased risks of childhood heart conditions, abdominal wall defects, and improper development of the brain and spinal cord.  Untreated pain and fevers are also associated with miscarriage, preterm birth, and low birth weight.Bottom line: use acetaminophen only when necessary during pregnancy and stop taking it as soon as the need no longer exists.  Everything you put into your body, whether it be medications or food, is a double-edged sword.  This is particularly true during pregnancy.https://www.medscape.com/s/viewarticle/explainer-tylenol-safe-take-during-pregnancy-2025a1000nky?ecd=wnl_tp10_daily_250910_MSCPEDIT_etid7706152&uac=210582CN&impID=7706152https://pubmed.ncbi.nlm.nih.gov/38592388/https://ehjournal.biomedcentral.com/articles/10.1186/s12940-025-01208-0#acetaminophen #tylenol #pregnancy #pain #fever #birthdefects

For centuries, people have relied on materials such as concrete, steel, and wood for the construction of buildings, bridges, and other structures. However, researchers have started exploring a far less conventional material for building therapeutics at the molecular level—DNA. In this episode, Charlene Lancaster from The Scientist spoke with Björn Högberg, a professor of biophysics at the Karolinska Institute, to learn how his team is developing DNA-based nanorobots to fight cancer. The Scientist Speaks is a podcast produced by The Scientist's Creative Services team. Our podcast is by scientists and for scientists. Once a month, we bring you the stories behind news-worthy molecular biology research. This month's episode is sponsored by Crown Bioscience.

With Emma Svennberg, Karolinska Institute, Stockholm -  Sweden, Sabine Ernst, Royal Brompton Hospital, London - UK, Stefan Simovic, Faculty of Medical Sciences, University of Kragujevac, Kragujevac - Serbia and Dominik Linz, Maastricht University Medical Centre (MUMC), Maastricht - The Netherlands. During this podcast, Emma Svennberg, Sabine Ernst, Stefan Simovic and Dominik Linz will tackle EHRA–ESC–HRS scientific statement sets new standards for trustworthy AI in electrophysiology, using a 29-item reporting checklist. EP Europace: State of the Art of Artificial Intelligence in Clinical Electrophysiology in 2025: A Scientific Statement of the European Heart Rhythm Association (EHRA) of the ESC, the Heart Rhythm Society (HRS), and the ESC Working Group on E-Cardiology

Patient-reported outcomes (PROs) have become a critical tool for capturing the lived experience of multiple sclerosis (MS), offering a perspective that extends beyond traditional clinical and imaging metrics. As research increasingly prioritises real-world relevance and individualised care, PROs provide valuable insights into symptoms such as fatigue, mood changes, and cognitive decline—factors that often evade objective measurement but have a profound impact on quality of life. Professor Jan Hillert of Karolinska Institute in Sweden and chair of the Swedish MS Registry joins host Brett Drummond of MStranslate to discuss how patient reported data are being integrated into clinical trial design and observational studies. They also explore current limitations to their use and highlight best practices for validation and interpretation. 

How can Canada reduce its rising number of HIV cases? Guest: Dr. Julio Montaner, Executive Director of the BC Centre for Excellence in HIV/AIDS Should BC end its 50-50 rule? Guest: Bridgette Anderson, President and CEO of the Greater Vancouver Board of Trade How does tickling work? Guest: Dr. Konstantina Kilteni, Assistant Professor in the Neuroscience Department at the Karolinska Institute and Head of the Tickle Lab What's happening with the LA riots? Guest: Reggie Cecchini, Washington Correspondent for Global News Are we digitally illiterate? Guest: Anita Hagh, Researcher at McGill University Learn more about your ad choices. Visit megaphone.fm/adchoices

How does tickling work? Guest: Dr. Konstantina Kilteni, Assistant Professor in the Neuroscience Department at the Karolinska Institute and Head of the Tickle Lab Learn more about your ad choices. Visit megaphone.fm/adchoices

First up on the podcast, Online News Editor Michael Greshko joins host Sarah Crespi to talk about stories set high above our heads. They discuss capturing fungal spores high in the stratosphere, the debate over signs of life on the exoplanet K2-18b, and a Chinese contender for world's oldest star catalog.   Next on the show, a look into long-standing questions on why and how our bodies respond to tickling. Producer Meagan Cantwell talks to Konstantina Kilteni, an assistant professor at the Donders Institute for Brain, Cognition and Behaviour and the Department of Neuroscience at the Karolinska Institute. They discuss how standardizing approaches to testing tickling in the lab could get us closer to answers.   Finally in this episode, the first in our book series on the science of death, with books host Angela Saini. Saini interviews Nobel Prize–winning biologist Venki Ramakrishnan about developments in longevity research and his book Why We Die: The New Science of Aging and the Quest for Immortality.   This week's episode was produced with help from Podigy.   About the Science Podcast Authors: Sarah Crespi, Angela Saini, Michael Greshko, Meagan Cantwell Learn more about your ad choices. Visit megaphone.fm/adchoices

In this illuminating episode we speak with Dr. Filippa Juul. An epidemiologist and leading researcher on the impact of ultra-processed foods (UPFs) on human health. Together, we unpack what ultra-processed really means, why it's not just about calories or macros, and how these foods are stealthily contributing to the global rise in obesity, chronic illness, and food addiction. Dr. Filippa Juul is a nutritional epidemiologist and Faculty Fellow at the Department of Public Health Policy and Management at the New York University School of Global Public Health (NYU GPH). She earned her PhD in Epidemiology from NYU GPH in 2020, following a MSc in Public Health Nutrition from the Karolinska Institute in Stockholm, Sweden, and a BA in Nutrition and Dietetics from Universidad Autónoma de Madrid in Spain. Dr. Juul's research focuses on improving cardiometabolic health outcomes at the population level, with a particular interest in the role of ultra-processed foods (UPFs) in diet quality, obesity, and cardiovascular disease. She utilizes large U.S. population studies to examine these associations and is also exploring the biological mechanisms underlying the impact of UPFs on cardiometabolic health.  Dr. Juul explains the NOVA classification system, dives into recent groundbreaking studies, and offers insights into why UPFs are so difficult to resist—and what we can do about it, both individually and at the policy level. Key Takeaways 

First up on the podcast, Online News Editor Michael Greshko joins host Sarah Crespi to talk about stories set high above our heads. They discuss capturing fungal spores high in the stratosphere, the debate over signs of life on the exoplanet K2-18b, and a Chinese contender for world's oldest star catalog.   Next on the show, a look into long-standing questions on why and how our bodies respond to tickling. Producer Meagan Cantwell talks to Konstantina Kilteni, an assistant professor at the Donders Institute for Brain, Cognition and Behaviour and the Department of Neuroscience at the Karolinska Institute. They discuss how standardizing approaches to testing tickling in the lab could get us closer to answers.   Finally in this episode, the first in our book series on the science of death, with books host Angela Saini. Saini interviews Nobel Prize–winning biologist Venki Ramakrishnan about developments in longevity research and his book Why We Die: The New Science of Aging and the Quest for Immortality.   This week's episode was produced with help from Podigy.   About the Science Podcast Authors: Sarah Crespi, Angela Saini, Michael Greshko, Meagan Cantwell Learn more about your ad choices. Visit megaphone.fm/adchoices

How can we cope with the loss of life's meaning and the helplessness that often accompanies it? What are the most common causes behind such a crisis? How can we signal our emotional state to those around us, and how can we support others in similar pain? How do we talk about difficult emotions, loneliness, and a sense of meaninglessness? What helped people who were close to that edge? What does science say about suicidal tendencies as a phenomenon? Can we better understand these circumstances and prevent tragedies more effectively? How does contemporary culture affect an individual's mental well-being? How is euthanasia perceived in light of today's psychiatric knowledge? These fundamental and deeply challenging questions were explored by psychiatrist Prof. Christian Rück from the Karolinska Institute in Stockholm, in conversation with psychologist and psychotherapist Dr. Marta Porębiak. Strefa Psyche Uniwersytetu SWPS is a project that promotes psychological knowledge at the highest substantive level and explores the practical applications of psychology in various areas of both private and professional life. The project includes online initiatives aimed at supporting personal growth for anyone in need or interested — regardless of where they are. Learn more about the project: https://web.swps.pl/strefa-psyche

In 1991, Professor Sten Nilsson and his PhD student Bo Lennernäs realised that the prostate, contrary to prevailing beliefs, is a mobile organ. A study confirmed their observations, and the new findings were included in Bo Lennernäs's doctoral thesis in 1995. The discovery quickly influenced prostate cancer radiotherapy practices across the world. In the papers of the thesis, they also demonstrated that it was possible to track the prostate's movements in a phantom model by inserting a small magnet that transmitted signals to an external receiver. These two findings led to the founding of Micropos Medical AB. Discovering more about Prostate Cancer Sten Nilsson, now a retired senior consultant at Karolinska University Hospital and Professor Emeritus at the Karolinska Institute, has dedicated over 40 years of his career to oncology, with a particular focus on prostate cancer. He has been involved in numerous pioneering research projects and developed new, crucial treatment concepts that are now used globally. Decades of Development When Sten Nilsson treated his first prostate cancer patients in the late 1970s, very few were cured. The tools and techniques for diagnosing and assessing whether the cancer was local or had spread were insufficient, as was radiotherapy. The available X-ray technology could visualise the pelvic skeleton but not the prostate, meaning its position had to be estimated based on the anatomy of the pelvic bones. Radiotherapy was cumbersome and time-consuming to administer, with limited impact on the tumours. "Patients whose cancer was assessed as local received radiotherapy with what we called a 'curative intention'. But in practice, most returned after a while, and the disease remained - eventually spreading," says Sten Nilsson. In the mid-1980s, surgery for localised prostate cancer began delivering better outcomes than radiotherapy. However, radiotherapy also advanced rapidly. Computed tomography (CT) became available, allowing the prostate and sometimes the tumour area to be visualised, which created entirely new conditions for treatment. Subsequently radiotherapy equipment, radiobiological research, and various imaging technologies like CT, MRI, ultrasound and others, also underwent enormous development. The 1990s saw the introduction of high-dose-rate brachytherapy (HDR-BT), a method to which Sten Nilsson made significant contributions. It involves inserting 15-20 hollow needles through the skin into the prostate, through which radiation is delivered. Today, HDR-BT is often combined with external beam radiotherapy in cases of locally advanced prostate cancer. A Discovery that Overturned Accepted Knowledge It was during HDR-BT procedures in 1991 that Sten Nilsson and Bo Lennernäs discovered that the prostate changes position under various conditions. "We used ultrasound to correctly position the needles in the prostate. We then observed that if a patient was anxious, perhaps coughed, raised an arm to scratch their head or simply spoke, the prostate moved. It was a true 'aha' moment. The common belief around the world was that the prostate is firmly anchored in the pelvis. We immediately realized that we had to find a way to describe and document the movement of the prostate, how much and in which directions the prostate moved", Sten Nilsson explains. Years earlier, he had treated prostate cancer patients by implanting radioactive gold seeds into the prostate to deliver a strong local radiation dose. The method was abandoned when seed production ceased, but the treated patients retained the seeds (they were not surgically removed) - creating an opportunity to document the discovery of prostate movement. "The gold seeds, and thus the prostate's position, are visible on X-rays. We called in a number of the former patients and took images under various conditions. For example, while straining versus relaxing, with full versus emptied bladder, and so forth. We found that the prostate frequently moved by ...

Dr. Cynthia Bulik is a clinical psychologist and one of the world's leading experts on eating disorders. She is the Founding Director of the University of North Carolina Center of Excellence for Eating Disorders and also the founder director of the Centre for Eating Disorders Innovation at Karolinska Institutet in Stockholm, Sweden. Dr. Bulik is Distinguished Professor of Eating Disorders in the Department of Psychiatry at UNC, Professor of Nutrition in the Gillings School of Global Public Health, and Professor of Medical Epidemiology and Biostatistics at Karolinska Institute.  Dr Bulik has received numerous awards for her pioneering work, including Lifetime Achievement Awards from the National Eating Disorders Association, the Academy for Eating Disorders, and the International Society of Psychiatric Genetics. She has written over 750 scientific papers, and several books aimed at educating the public about eating disorders.  Currently, Dr. Bulik's focus  is in the reconceptualization of eating disorders as being a metabo-psychiatric diseases. Food Junkies is keen to explore this interest in how metabolic disease plays a role in disordered eating: can this construct be the  common ground to start to understand the muddy waters  between eating disorders and food addiction?  In This Episode, You'll Learn:

Vidcast:  https://www.instagram.com/p/DJHrndtOyB4/A painless, shot-free urine test could diagnose prostate cancer at its earliest, treatable stages.  Biochemists in Sweden, the UK, and China, led by those at the Karolinska Institute, studied mRNA activity in more than 2000 patients with and without prostate cancers.  They used AI to identify the proteins specific for prostate cancer that show up in the urine of those with this disease.Following this identification phase, the researchers now plan to further validate this urine prostatic cancer test in larger clinical trials.  Once this type of testing becomes the standard for prostatic cancer diagnosis, expect its use for monitoring following the medical and surgical therapeutic measures to eradicate prostate cancer.https://dx.doi.org/10.1158/0008-5472.CAN-25-0269https://medicalxpress.com/news/2025-04-urine-reveal-prostate-cancer.html#prostate #cancer #urine #screening #ai

00:00:00 - Surf's Up: Season 6 Episode 2Surfing the MASH Tsunami continues its coverage of the AASLD Emerging Trends Conference on MASLD, MetALD and ALD. This week, the panelists focus on disease epidemiology and what it can teach us about the relative importance of alcohol and diet on disease progression. Our newsmaker, hepatology KOL and frequent Surfer Hannes Hagstrom, discusses what a recent paper demonstrates about the impact of MASLD on 15-year mortality and cause of death and how this information can improve patient care. Finally, our Expert, Shelbyville, Indiana internist Emily Ann Andeya, discusses her path from practicing internal medicine to focus on liver health (HINT: the common theme is insulin resistance).00:04:40 - IntroductionHost Roger Green briefly describes this episode's three sections and one key lesson from each.00:05:49 - Roundtable: Highlights from the AASLD Emerging Trends Conference, Part 2 The second portion of our Roundtable focuses on relative impact of alcohol and diet on disease progression and overall mortality and morbidity. It starts with Aleksander Krag sharing the highlights of his epidemiology presentation at the Emerging Trends Conference. Dr. Krag points out that while the vast majority of SLD patient live with MASLD, the vast majority of hospitalized patients and those living with late-stage cirrhosis live with ALD. Similarly, for the average patient, living with MetALD is more lethal than living with MASLD. Aleksander points out another challenge in defining where a patient lives on the ALD -> MetALD -> MASLD spectrum: patients' level of alcohol consumption is likely to change over time and many ALD or MetALD cirrhosis patients stop drinking altogether. The rest of this section considers the importance of stigma in correctly classifying patients and why genetics may become key to a message that minimizes patient stigma.00:25:50 - Newsmaker: Hepatology Researcher and KOL Hannes Hagstrom of the Karolinska Institute joins Roger to discuss cause-specific mortality in Swedish MASLD patientsOn March 24, the Journal of Hepatology posted a paper titled Cause-specific mortality in 13,099 patients with metabolic dysfunction-associated steatotic liver disease in Sweden. Co-author Hannes Hagstrom joins Roger to discuss the paper's key findings and implications for care. The key finding: living with MASLD leads to a significant increase in 15-year mortality. The most frequent cause of death among MASLD patients is cardiovascular disease, but the greatest increases in relative risk were due to HCC (HR ~ 35) and extra-hepatic cancers (HR ~ 26). Hannes points out that these results can serve as the beginning of a process where physicians can compute the risk at which individual patients place themselves through diet or alcohol patterns, which can aid patient understanding of the disease.00:44:22 - Experts: Internist Emily Ann Andeya discusses how she developed the commitment to treating liver disease that made her a "unicorn" in the words of one AASLD panelist and also brought her to attend the Emerging Trends Conference last monthRoger first met Emily Ann Andeya when she asked a question at a session of last fall's The Liver Meeting, and again at the Emerging Trends Conference, where Emily and her colleagues were likely the only primary care physicians in the room. Emily describes the path by which she went from wanting to be a cardiologist during medical school in the Philippines through years of nursing in the US to primary care practice and, how, focus on the liver as a key to overall metabolic health. Listen as Emily explains the importance of understanding insulin resistance in her transition, and how her vision affects the way she and her colleagues practice, the goals they set, and the exceptional levels of care they achieve.01:08:56 Business Report

For years, antidepressants have been the default solution for dementia patients struggling with depression, anxiety, and aggression. But what if they're actually making things worse? A groundbreaking new study from the Karolinska Institute has found that dementia patients on SSRIs like Lexapro, Celexa, and Zoloft experience faster cognitive decline than those not on medication. Are we treating symptoms at the cost of accelerating the disease itself? In this episode, Dr. Bray dives into the science behind these findings. We'll explore: -How SSRIs impact the aging brain—and why they may be ineffective for many people -The hidden risks of antidepressants, including cognitive fog, emotional blunting, and increased fall risk -A smarter approach to dementia care—why non-drug interventions should be considered first The truth is, there's no one-size-fits-all answer when it comes to mental health and dementia. What works for one person may not work for another. That's why it's critical for patients, caregivers, and medical professionals to stay informed, ask questions, and do their own research before making treatment decisions. If you or a loved one is facing a decision about antidepressants and dementia, this is an episode you can't afford to miss. Listen now, and make sure you have all the facts before choosing a treatment plan because better decisions start with better knowledge. QUOTES BY DR. BRAY "Your brain health and your physical health are your responsibility. Do not abdicate them to somebody else." "Consider non-drug interventions first—therapy, lifestyle changes, and social engagement can be powerful tools." "We need to ask questions and look for signs—because sometimes, the biggest tragedies come from what we didn't see."  

Many of us are lucky to grow older, and in Europe there is an aging demographic. With this come the diseases of aging such as dementia. For a long time people have thought this inevitable but we will learn today that, as with so many diseases, lifestyle changes from a young age can counteract this, to reduce the risk of getting dementia and also stabilising mental decline. In 2021, 20.8% of the EU population was aged 65 years or older. In 2019, an Alzheimer Europe report on the prevalence of dementia estimated that there were about 9 million people living with the disease in Europe. This number is projected to double by 2050, rising towards 19 million in the European region. Globally, there are around 55 million people worldwide who are living with dementia. However, research is now showing that up to 45% of dementias could be prevented: by addressing a range of modifiable risk factors, at different stages of our lives. My guests today are: Dr. Ange Bradshaw: Director for Research at Alzheimer's Europe Dr. Joëlle Fritz: Research and Strategy Specialist, Luxembourg Institute of Health Dr. Francesca Mangialasche: Geriatrician, Division of Clinical Geriatrics: Alzheimer Research Center Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Executive Director of the World-Wide FINGERS Global Scientific Coordinating Center at the FINGERS Brain Health Institute Hassan Fadli: Founder, 5 Ironmans Beat Alzheimer's Association The 2024 World Alzheimer's report noted that 80% of people think dementia is a normal part of ageing, and 65% of healthcare professionals. Only 2% of the population are affected by rare genetic factors but for most of us this is not the case. ‘Modifiable risk factors' can be replaced to deter and stall dementia. Francesca Mangialasce is based at the Karolinska Institute in Sweden, and also works as executive director of the ‘FINGERS' Brain Health Institute, founded by Professor Mija Kivipelto, a world renowned researcher in the field of Alzheimer's disease and Dementia. FBHI is dedicated to promoting healthy brain aging and preventing cognitive impairment and dementia through innovative multi-domain clinical research and the fast translation of these results into personalised clinical practice. Brain is our main capital, and there is so much we can do to promote brain health. Studies have show that cardiovascular and metabolic disorders such as high blood pressure, high blood cholesterol, high blood sugar or diabetes are risk factors for dementia. There are many other emerging factors such as hearing impairment, vision loss, impaired oral health.  Being mentally, physically and socially active during life is important to reduce the risk of memory problems in old age. Secondary and tertiary prevention is also really important, even at the later stages of disease with therapies including art, dance and cognitive stimulation therapy .  The FINGER study across 70 countries shows that a multi-domain approach can benefit cognition:exercise, healthy diet, cognitive training, good control of metabolic/vascular disorders, and social stimulation. Stigma Hassan Fadli's father faced stigma in the village he lived all his life. This stigma deepens the pain of the suffering, knowing you are losing ‘yourself'. It is also a burden for the caregivers at a time when family and friends need the most help to support their loved one.   Hassan promised his father to work towards breaking this stigma and founded the 5 Ironmans initiative. Hassan has also made a documentary of his advocacy work alongside the endurance sport to reach people from children in schools across Europe to the Queen of Sweden.  His aim is to bring brain health into normal conversation, break the stigma, and integrate brain health awareness into public discourse.  Luxembourg support Joëlle Fritz is working  as Research and Strategy Specialist at the Luxembourg Institute of Health where she aims to bridge research to clinical care. "Programme démence prevention" (pdp) is a programme raising awareness on modifiable risk factors for dementia prevention and promotes life style changes. PDP is an integrated prevention concept funded by Luxembourg's Ministry of Health and Social Security. PDP is currently coordinated by the Centre Hospitalier  de Luxembourg in collaboration with national institutions (Luxembourg Institute of Health and Luxembourg Centre for System's Biomedicine at the University of Luxembourg) and partner associations (listed below). It is important to start as early as possible in the prevention of dementia, and so the PDP Braincoach app was created, accessible via browser to everyone also outside Luxembourg: www.pdp-app.lu Associations related in Luxembourg: L'Association nationale des diététiciens du Luxembourg: www.andl.lu ZithaAktiv: www.zithaaktiv.lu   Club Seniors of HELP asbl: www.help.lu Club Senior “Schwaarze Wee” Dudelange:   www.schwaarzewee.lu Lëtzebuerger Verein fir Gediechtnistraining: www.lvgt.lu NEUROvitalis home and digital Info-Zenter Demenz:   www.demenz.lu Association Luxembourg Alzheimer (ala) : www.ala.lu  Longevity with health  The results are clear, for dementia and living a long life with good health: we need to put in place good habits of physical, social and mental health.  Links to the notes above: https://www.5ironmansbeatalzheimer.com www.pdp.lu https://www.alzheimer-europe.org https://fbhi.se/sv/ https://www.linkedin.com/company/fingers-brain-health-institute/ https://www.linkedin.com/in/miia-kivipelto-8a8b1b3b/ https://www.chl.lu/fr https://m3s.gouvernement.lu/en.html https://www.uni.lu/lcsb-en/ https://ki.se/en

Many of us are lucky to grow older, and in Europe there is an aging demographic. With this come the diseases of aging such as dementia and a burden on family and society for care. For a long time people have thought this inevitable but we will learn today that, as with so many diseases, lifestyle changes from a young age can counteract this, to reduce the risk of getting dementia and also stabilising mental decline. In 2021, 20.8% of the EU population was aged 65 years or older. In 2019, an Alzheimer Europe report on the prevalence of dementia estimated that there were about 9 million people living with the disease in Europe. This number is projected to double by 2050, rising towards 19 million in the European region. Globally, there are around 55 million people worldwide who are living with dementia. However, research is now showing that up to 45% of dementias could be prevented: by addressing a range of modifiable risk factors, at different stages of our lives. My guests today are: Dr. Ange Bradshaw: Director for Research at Alzheimer's Europe Dr. Joëlle Fritz: Research and Strategy Specialist, Luxembourg Institute of Health Dr. Francesca Mangialasche: Geriatrician, Division of Clinical Geriatrics: Alzheimer Research Center Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Executive Director of the World-Wide FINGERS Global Scientific Coordinating Center at the FINGERS Brain Health Institute Hassan Fadli: Founder, 5 Ironmans Beat Alzheimer's Association The 2024 World Alzheimer's report noted that 80% of people think dementia is a normal part of ageing, and 65% of healthcare professionals. Only 2% of the population are affected by rare genetic factors but for most of us this is not the case. ‘Modifiable risk factors' can be replaced to deter and stall dementia. Francesca Mangialasce is based at the Karolinska Institute in Sweden, and also works as executive director of the ‘FINGERS' Brain Health Institute, founded by Professor Mija Kivipelto, a world renowned researcher in the field of Alzheimer's disease and Dementia. FBHI is dedicated to promoting healthy brain aging and preventing cognitive impairment and dementia through innovative multi-domain clinical research and the fast translation of these results into personalised clinical practice. Brain is our main capital, and there is so much we can do to promote brain health. Studies have show that cardiovascular and metabolic disorders such as high blood pressure, high blood cholesterol, high blood sugar or diabetes are risk factors for dementia. There are many other emerging factors such as hearing impairment, vision loss, impaired oral health.  Being mentally, physically and socially active during life is important to reduce the risk of memory problems in old age. Secondary and tertiary prevention is also really important, even at the later stages of disease with therapies including art, dance and cognitive stimulation therapy .  The FINGER study across 70 countries shows that a multi-domain approach can benefit cognition:exercise, healthy diet, cognitive training, good control of metabolic/vascular disorders, and social stimulation. Stigma Hassan Fadli's father faced stigma in the village he lived all his life. This stigma deepens the pain of the suffering, knowing you are losing ‘yourself'. It is also a burden for the caregivers at a time when family and friends need the most help to support their loved one.   Hassan promised his father to work towards breaking this stigma and founded the 5 Ironmans initiative. Hassan has also made a documentary of his advocacy work alongside the endurance sport to reach people from children in schools across Europe to the Queen of Sweden.  His aim is to bring brain health into normal conversation, break the stigma, and integrate brain health awareness into public discourse.  Luxembourg support Joëlle Fritz is working  as Research and Strategy Specialist at the Luxembourg Institute of Health where she aims to bridge research to clinical care. "Programme démence prevention" (pdp) is a programme raising awareness on modifiable risk factors for dementia prevention and promotes life style changes. PDP is an integrated prevention concept funded by Luxembourg's Ministry of Health and Social Security. PDP is currently coordinated by the Centre Hospitalier  de Luxembourg in collaboration with national institutions (Luxembourg Institute of Health and Luxembourg Centre for System's Biomedicine at the University of Luxembourg) and partner associations (listed below). It is important to start as early as possible in the prevention of dementia, and so the PDP Braincoach app was created, accessible via browser to everyone also outside Luxembourg: www.pdp-app.lu Associations related in Luxembourg: L'Association nationale des diététiciens du Luxembourg: www.andl.lu ZithaAktiv: www.zithaaktiv.lu   Club Seniors of HELP asbl: www.help.lu Club Senior “Schwaarze Wee” Dudelange:   www.schwaarzewee.lu Lëtzebuerger Verein fir Gediechtnistraining: www.lvgt.lu NEUROvitalis home and digital Info-Zenter Demenz:   www.demenz.lu Association Luxembourg Alzheimer (ala) : www.ala.lu  Longevity with health  The results are clear, for dementia and living a long life with good health: we need to put in place good habits of physical, social and mental health.  Links to the notes above: https://www.5ironmansbeatalzheimer.com www.pdp.lu https://www.alzheimer-europe.org https://fbhi.se/sv/ https://www.linkedin.com/company/fingers-brain-health-institute/ https://www.linkedin.com/in/miia-kivipelto-8a8b1b3b/ https://www.chl.lu/fr https://m3s.gouvernement.lu/en.html https://www.uni.lu/lcsb-en/ https://ki.se/en

To support the channel make your donation here: https://www.gofundme.com/f/t5kvv-being-and-doing-podcast-to-sustain-and-thrive?utm_campaign=p_lico+share-sheet-first-launch&utm_medium=copy_link&utm_source=customerTHIS IS A PLACE WHERE SUCCESS MEETS SERENITY.I am Aleksandra Vancevska, gestalt therapeutic counsellor and UKCP student therapist. I support you to transform overachieving burnout, stress, perfectionism and stuckness into fulfilling self-confidence and authentic success.To start therapy with me schedule a free consultation: https://calendly.com/aleksandra-vanch...If you like what you hear please share, like and subscribe so these stories can reach more people.⁠Elena Hoffer is passionate about helping early career researcher finding full filling careers outside of academia. She received her PhD from Karolinska Institute in Stockholm, Sweden in November 2023. During her PhD she organized careers session for PhDs and postdocs to help them to understand their options after academia. Since 2024, she is running the company Alma.Me which equips early career researchers with tools and knowledge to empower them in their transition. Follow Elena on Linkedin: https://www.linkedin.com/in/elena-hoffer-/Find all the links to work with me in one place:Linktr.ee: https://linktr.ee/being_and_doing This podcast represents my own and my guests views and opinions. The content here should not be taken as medical, financial or any other advice. The content is for informational purposes only, and because each person is so unique, please consult the appropriate professional for any specific questions you have.Thank you for joining me on this journey

In "Common Side Effects," the starring scientist finds a mushroom that can heal any ailment. But powerful people will do anything to stop him from cultivating it. And, a combination of environmental factors and the way our bodies function play a role in how we perceive the smell of snow.In ‘Common Side Effects,' A Clash Over An All-Healing MushroomIn the new Adult Swim show “Common Side Effects,” an eccentric scientist has a secret: He's discovered a strange mushroom that can cure any illness or injury, and he wants to get it to people in need. The only problem is that a pharmaceutical company doesn't want that secret to get out and will do anything to make sure he's stopped.Joining Host Flora Lichtman to break down this fungal drama, and the science that inspired it, are the show's creators, Steve Hely, who previously wrote for “30 Rock” and “Veep;” and Joe Bennett, creator of the animated sci-fi show “Scavengers Reign” on Max.Why Snow Has That Crisp, Clean SmellIf you know snow, you might know that it has a particular smell to it. It has to do with where you are and how cold it is. It may even involve the memory parts of your brain.Producer Rasha Aridi talks with Host Flora Lichtman about the science behind that snowy smell, featuring Dr. Johan Lundström, snow aficionado and professor of psychology at the Karolinska Institute in Stockholm, Sweden.Transcripts for each segment will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

Dr Glenn McConell chats with Dr Tommy Lundberg from the Karolinska Institute in Stockholm, Sweden. He is an expert on resistance training (RT) and has focussed on the effect of concurrent training on exercise adaptations. That is, does doing concurrent resistance and endurance training affect the responses to resistance and endurance training compared to doing either alone. His research has specifically focused on the effects of endurance training on resistance training adaptations although we also discussed the effect of resistance training on endurance training adaptations. It appears that in many people concurrent training has either no interfering effect or may even be beneficial. However there is some limited research that endurance training, although not affecting hypertrophy, may reduce strength and/or speed of contraction. He has also done a lot of work on biological males been involved in female sports (which will be converted in a future podcast). I found it a very interesting chat. Enjoy! X: @TLexercise. 0:00. Introduction 3:03. Tommy's background 5:25. Aland Islands 7:25. What is concurrent training? 9:40. Resistance training (RT) can benefit endurance performance 13:35. Does RT affect injuries? 15:05. The amount/volume of training and concurrent training 18:32. Little effect of endurance training on hypertrophy but might effect strength 21:30. Glenn's frustrations at the gym 24:15. Single-leg research studies vs whole body exercise 31:20. AMPK and metabolism etc 34:00. Potential mechanisms involved 35:40. Interference of endurance on strength hasn't been clearly shown 38:00. RT can improve endurance performance and economy 41:10. Specificity of RT adaptations 45:55. Running straight after the gym 48:55. How much RT is enough/sufficient/optimal 51.20. Benefits of circuit training 53:05. Endurance exercise interfering with strength/contraction speed 54:20. Relationship between muscle size and strength 59:05. Explosive RT best for endurance exercise 1:04:35. Order of the concurrent training 1:06:35. Arterial stiffness/health and concurrent training 1:10:25. Team sports and concurrent training 1:12.08. Different sports a concurrent training 1:13:05. Mechanisms: gene expression etc 1:16:22. Fatigue and concurrent training 1:17:40. If short on time what exercise would you recommend? 1:19:55. Sex differences? 1:20:45. Age effects? 1:21:20. Controversies in the field 1:24:25. Things that influencers can get wrong 1:25:45. Other areas that he is investigating 1:27:50. Anti inflammatories can reduce resistance training gains 1:30:08. Takeaway messages 1:31:14. Outro Inside Exercise brings to you the who's who of research in exercise metabolism, exercise physiology and exercise's effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all. The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University. He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9). Connect with Inside Exercise and Glenn McConell at: Twitter: @Inside_exercise and @GlennMcConell1 Instagram: insideexercise Facebook: Glenn McConell LinkedIn: Glenn McConell https://www.linkedin.com/in/glenn-mcconell-83475460 ResearchGate: Glenn McConell Email: glenn.mcconell@gmail.com Subscribe to Inside exercise: Spotify: shorturl.at/tyGHL Apple Podcasts: shorturl.at/oFQRU YouTube: https://www.youtube.com/@insideexercise Anchor: https://anchor.fm/insideexercise Google Podcasts: shorturl.at/bfhHI Anchor: https://anchor.fm/insideexercise Podcast Addict: https://podcastaddict.com/podcast/4025218 Not medical advice

How close are we to predicting psoriatic arthritis (PsA) before it strikes? In this episode of Inside GRAPPA, Dr. Fabian Proft sits down with two esteemed researchers, Dr. Axel Svedbom and Professor Mona Ståhle, from the Karolinska Institute in Stockholm, to discuss their groundbreaking study on predicting PsA in patients with new-onset psoriasis. Funded by the GRAPPA Pilot Research Grant, this project is poised to revolutionize early detection and intervention strategies for psoriatic disease.Listen as they discuss: The innovative predictive models combining machine learning with clinical data. Key findings, including the significance of arthralgia as a predictive marker for PsA. How their research could reshape clinical practices and improve patient outcomes.Featured Guests Dr. Axel Svedbom: Postdoctoral researcher specializing in registry-based research and health economics, with over a decade of focus on psoriasis and psoriatic arthritis. Professor Mona Ståhle: Dermatologist and researcher dedicated to advancing understanding and treatment of psoriatic disease.Resources & Links Stay updated with GRAPPA's initiatives: GRAPPA Website. Explore previous episodes of Inside GRAPPA: Podcast Archive.

Dr. Lena Ekström is a Hospital Chemist at Karolinska University Hospital and an Adjunct Professor of Pharmacology in the Department of Laboratory Medicine at the Karolinska Institute, where she specializes in Doping Research. In this interview, we discuss her career and some of the research she has conducted examining various factors that can influence anti-doping test results including interactions with other substances, genetics, hormone cycles, biological variability, and micro-dosing.

Send us a textIn this episode, we explore the delicate dance between artificial intelligence and biological research with Lars Brandén, Director of Biology at Kolibri. From his early fascination with gene therapy to pioneering high-throughput screening centers at prestigious institutions, Lars shares invaluable insights on bridging the gap between academic innovation and industrial application.What sets this conversation apart is Lars' compelling perspective on why the popular "agile development" model doesn't always translate smoothly to bioprocess development – and why that matters for the future of drug development. His journey from the Karolinska Institute to leading cutting-edge biological research offers a unique lens on the evolution of biotech.Key takeaways for listeners:Learn why scientists must develop broader cross-disciplinary knowledge to effectively leverage AI tools in researchDiscover how AI could dramatically reduce drug development timelines and costs within the next five yearsUnderstand the potential for AI to democratize access to cell and gene therapies through optimized production methodsJoin us for this fascinating exploration of how domain expertise and artificial intelligence can work in harmony to accelerate breakthrough therapies. Whether you're a biotech professional or simply curious about the future of medicine, this episode offers valuable insights into the transformation of drug development in the AI era.Listen now to discover how the intersection of human expertise and artificial intelligence is reshaping the future of personalized medicine.Connect with Lars Brandén:LinkedIn: https://www.linkedin.com/in/larsbrandenNext Steps:Wondering how to develop cell and gene therapies with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessmentDevelop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at hello@bruehlmann-consulting.com

A new JAMA study examines the association between severe maternal morbidity in a first birth and the probability of a subsequent birth. Authors Neda Razaz, PhD, and Eleni Tsamantioti, MD, MMedSc, both from the Karolinska Institute in Sweden, discuss this and more with JAMA Associate Editor Melissa A. Simon, MD, MPH. Related Content: Association of Severe Maternal Morbidity With Subsequent Birth Severe Maternal Morbidity and Subsequent Birth—Understanding and Informing a Woman's Choice

Vincent travels to the Karolinska Institute in Stockholm to meet up with Niklas Björkström and Joakim Dillner to review their research on the endometrial immune system, and the plan to eliminate cervical cancer in Sweden. Host: Vincent Racaniello Guests: Niklas Björkström and Joakim Dillner Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server Endometrial immune system variation (Sci Immunol) Immune defense in the womb (News from Karolinska) HPV vaccination and screening for elimination (Nat Comm) Cervical cancer elimination strategies (Int J Cancer) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

A boatload of Swedish identical twins, aged 11 to 80, descended into Felixstowe on 7th October, 1977 - wearing matching outfits - for a shopping trip.  The eye-catching stunt was part of a scientific project led by ship captain Sune Dahlström, a twin himself, in collaboration with the Swedish Twin Register at the Karolinska Institute in Stockholm, and aimed to study the similarities and differences in their behaviours. Twin studies have a long history, with dark roots in Victorian eugenics and, infamously, Nazi experiments. However, the Swedish Twin Register became a more positive force for scientific discovery, meticulously based on twin birth records from parishes across Sweden, and today holding data on nearly 100,000 pairs of twins, making it the most comprehensive collection of its kind. In this episode, Arion, Rebecca and Olly celebrate the accomplishments of the Swedish Twin Register; discover how education impacts longevity; and consider why on Earth Felixstowe, of all places, played host to this unusual event… Further Reading: • ‘“As twins we're useful”' (Karolinska Institutet, 2017): https://ki.se/en/research/popular-science-and-dialogue/spotlight-on/spotlight-on-participating-in-research/as-twins-were-useful • ‘Seeing Double: How History Became Obsessed With Twins' (Google Arts & Culture): https://artsandculture.google.com/story/seeing-double-how-history-became-obsessed-with-twins/XgIiH-H78-86LQ • ‘What identical twins separated at birth teach us about genetics' (BBC REEL, 2022): https://www.youtube.com/watch?v=JMlJcOSRX-8 Love the show? Support us!  Join 

Emotion Regulation Individual Therapy for Adolescents (ERITA) and its internet-delivered version (IERITA) is just one of a couple of treatments developed specifically to address nonsuicidal self-injury (NSSI) among adolescents. In this episode, Dr. Johan Bjureberg from the Karolinska Institute in Stockholm, Sweden walks us through in detail each of the 11 sessions of IERITA and IERITA's 6 parallel sessions for parents.Learn more about Dr. Bjureberg's work here, and follow the Bjureberg Research Lab and their projects and publications at https://bjureberglab.se/. Below are links to his research on ERITA/IERITA referenced in this episode:Bjureberg, J., Ojala, O., Hesser, H., Häbel, H., Sahlin, H., Gratz, K. L., Tull, M. T., Knutsson, E. C., Hedman-Lagerlöf, E., Ljótsson, B., & Hellner, C. (2023). Effect of internet-delivered Emotion Regulation Individual Therapy for Adolescents with Nonsuicidal Self-Injury Disorder: A randomized clinical trial. JAMA Network Open, 6(7), e2322069.Bjureberg, J., Sahlin, H., Hedman-Lagerlof, E., Gratz, K. L., Tull, M. T., Jokinen, J., Hellner, C., & Ljotsson, B. (2018). Extending research on emotion regulation individual therapy for adolescents (ERITA) with nonsuicidal self-injury disorder: Open pilot trial and mediation analysis of a novel online version. BMC Psychiatry, 18, 326.Bjureberg, J., Sahlin, H., Hellner, C., Hedman-Lagerlof, E., Gratz, K. L., Bjarehed, J., Jokinen, J., Tull, M. T., & Ljotsson, B. (2017). Emotion regulation individual therapy for adolescents with nonsuicidal self-injury disorder: A feasibility study. BMC Psychiatry, 17, 411.Want to have a bigger role on the podcast?:Should you or someone you know be interviewed on the podcast? We want to know! Please fill out this Google doc form, and we will be in touch with more details if it's a good fit.Want to hear your question and have it answered on the podcast? Please send an audio clip of your question (60 seconds or less) to @DocWesters on Instagram or Twitter/X, or email us at thepsychologyofselfinjury@gmail.comWant to be involved in research? Send us a message at thepsychologyofselfinjury@gmail.com and we will see if we can match you to an active study.Want to interact with us through comments and polls? You can on Spotify!Follow Dr. Westers on Instagram and Twitter/X (@DocWesters). To join ISSS, visit itriples.org and follow ISSS on Facebook and Twitter/X (@ITripleS).The Psychology of Self-Injury podcast has been rated as one of the "10 Best Self Harm Podcasts" and "20 Best Clinical Psychology Podcasts" by Feedspot  and one of the Top 100 Psychology Podcasts by Goodpods. It has also been featured in Audible's "Best Mental Health Podcasts to Defy Stigma and Begin to Heal." Goodpods Top 100 Parents Podcasts Listen now to The Psychology of Self-Injury: ExploringSelf-Harm & Mental Health podcast Goodpods Top 100 Research Podcasts Listen now to The Psychology of Self-Injury: ExploringSelf-Harm & Mental Health podcast 

Vincent travels to the Karolinska Institute in Stockholm on 31 May 2024 to meet with Dr. Judith Bruchfeld and discuss her research on the etiology and treatment of Long COVID. Hosts: Vincent Racaniello Guest: Judith Bruchfeld Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server Immune system perturbations in Long COVID (J Immunol) Post-COVID immune system perturbations (J Immunol) Systems disregulation in Long COVID (Sci Rep) Clincal standards for diagnosing, treating, and preventing Long COVID (Intl J Tuberc Lung Dis) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

Want to send us a message? Fan mail? Thoughts on the episode?Dr Nils Bergman calls himself a Public Health Physician, and currently promotes and researches skin-to- skin contact on a full time basis. He is a Research Associate at the Karolinska Institute, Sweden. Dr. Bergman was born in Sweden and raised in Zimbabwe, where he also later worked as a mission doctor. He received his medical degree (MB ChB) at the University of Cape Town, a Diploma in Child Health at Uppsala University, and later a Masters in Public Health at the University of the Western Cape. During his years in Zimbabwe he completed a doctoral dissertation (MD, equivalent to PhD) on deadly scorpion stings. He has worked in South Africa, Zimbabwe and Sweden, and his last posting was Senior Medical Superintendent of Mowbray Maternity Hospital in Cape Town, overseeing 18000 births per year. He is married to Jill, and father to Rebecka, Simon and Emma, and has five grandchildren.In this episode, Dr. Bergman delves into the critical importance of maintaining skin-to-skin contact throughout the first day of a newborn's life. He explains how this practice not only connects and wires the baby's brain but also has profound effects on the mother.Dr. Bergman sheds light on the pivotal role of Oxytocin, often dubbed the 'love hormone,' which he eloquently describes as the hormone of resilience, vital for both mother and baby.We further explore the crucial significance of focusing not only on the first 1000 days of a child's life but also on the first 1000 minutes. Dr. Bergman passionately explains how these early moments are foundational for long-term health and emotional resilience.Additionally, we dive into the detailed work behind the latest version of the WHO Kangaroo Mother Care (KMC) document. Dr. Bergman shares insights into the creation of this and introduces us to the concept of 'nurture-science.' He discusses how this emerWant to listen to the new podcast 'The Feeding Couch'? Find it here or on all good podcast hosting platforms! Get 10% off Katie's Breastfeeding & Lactation: the fundamentals online course today with code POD10 at checkout. Support the Show. Please support the show via Patreon or BuyMeACoffee MERCH here! Music Joseph McDade Like this podcast? Leave us a review here Want more from Katie and Rachel? Katie's website Rachel's website DisclaimerThe information provided on this podcast does not, and is not intended to, constitute medical or legal advice; instead, all information available on this site are for general informational purposes only. The Midwives' Cauldron podcast reserves the right to supplement, change or delete any information at any time.The information and materials on the podcast is provided "as is"; no representations are made that the content is error-free. Whilst we have tried to ensure the accuracy and completeness of the information we do not warrant or guarantee the accurateness. The podcast accepts no liability for any loss or damage howsoever arising out of the use or reliance on the content.

Today Dr. David LeMay steps in to co-host with Dr. Ken Ford for our interview with Dr. Charles Serhan. Charles is a Harvard professor best known for his discovery of specialized pro-resolving mediators. SPMs are molecules that can activate the natural resolution of inflammation and help people avoid anti-inflammatory drugs. The discovery of SPMs spurred a paradigm shift in our understanding of inflammation and human disease. Charles is the Simon Gelman Professor of Anesthesia at Harvard Medical School and the director of the Center for Experimental Therapeutics and Reperfusion Injury at Brigham and Women's Hospital. He also is a co-director of the Brigham Research Institute. David, who was our guest on Episode 69 of STEM-Talk, is a sports medicine and rehabilitation physician with a Pensacola, Florida practice that focuses on lifestyle and performance medicine. He also is a visiting research scientist here at IHMC. Show notes [00:03:33] David opens the interview mentioning that Charles grew up in New York City with a passion for music. David explains that Charles learned to play the vibraphone in junior high and played professionally for a year before going to college. David asks Charles why he decided to pursue science instead of music. [00:04:22] Ken asks Charles what kind of vibraphone he plays. [00:06:02] Ken asks, aside from the desire to help people, if there was something particular about studying science that Charles really enjoyed. [00:06:45] David asks about Charles' experience at the State University of New York at Stonybrook studying biochemistry and immunohistochemistry. [00:07:16] David asks if there was any carry over of skills for Charles from his career in music to his career in science. [00:08:16] Ken mentions that after Charles earned his bachelor's degree, one of his professors persuaded him to go to New York University for a master's and Ph.D. Ken also mentions that at the time Charles worked in the lab of Gerald Wiseman at Woods Hole Marine Biological Laboratory and asks about that experience. [00:12:37] David asks if this experience led Charles to a focus on neutrophil membrane remodeling for his Ph.D. [00:13:59] David asks Charles if it was at the Karolinska Institute where he met his future wife. [00:14:38] Ken asks Charles about one of his mentors, Michael Heidelberg, who gave Charles advice about how to be a good scientist. [00:17:13] David explains that in the 1990's Charles discovered Specialized Pro-Resolution Mediators and has since pioneered a new field on the utility of SPMs for a variety of inflammatory diseases. [00:25:01] Ken backs up to ask Charles what drew him to study inflammation in the first place and how that led him to do more research on the subject than any other scientist. [00:26:26] David asks Charles to touch on some different types of inflammation that the body experiences. [00:35:12] Ken asks Charles about how a trip to Asia during which he developed a hole in his intestines, resulted in first-hand experience on the importance of controlling inflammation. [00:41:00] David asks if Charles was taking any non-steroidal anti-inflammatory medications when he developed peritonitis. [00:41:53] David asks Charles to explain what non-steroidal anti-inflammatory medications do to the healing process. [00:45:35] David brings up a recent discovery in animal models that as animals age, their ability to produce resolution mediators declines, possibly contributing to the loss of muscle mass with age. [00:48:09] Ken asks Charles to talk about the explosion of research into the potential therapeutic applications of SPMs in the treatment of a variety of chronic diseases known to be driven in part by chronic inflammation. [00:51:06] David asks Charles to explain the differences between resolvins, protectins, and maresins, as well as what role each plays in the healing process. [00:56:04] Ken mentions a review article that Charl...

In this week's Sweden in Focus we speak to Vida Mehrannia, the wife of the Karolinska Institute researcher Ahmedreza Djalali who was sentenced to death in Iran in 2017 and was not part of a recent prisoner exchange that saw two Swedes return home. Host Paul O'Mahony is joined this week Vida Mehrannia. She talks about why the family moved to Sweden, what life was like for them here before her husband's arrest. Also, after the release last month of two other Swedish prisoners in Iran, she tells us about what attempts have been made to secure Ahmedreza Djalali's release and if more could be done. READ ALSO: 'Why not me?' Imprisoned academic Djalali delivers stinging rebuke over prisoner swap Wife of imprisoned academic 'disappointed' after meeting Swedish foreign minister LISTEN: Anger over Sweden's prisoner swap with Iran Get Membership+ to listen to all The Local's podcastsSign up now and get early, ad-free access to a full-length episode of the Sweden in Focus podcast every weekend, as well as Sweden in Focus Extra every Wednesday.Please visit the link that applies to you and get a 40% discount on Membership+For signed-in members: Upgrade to Membership+For new members: Get Membership+ Read more about Membership+ in our help centre.Already have Membership+ but not receiving all the episodes? Go to the podcast tab on your account page to activate your subscription.  Become a member at https://www.thelocal.se/podcasts/podcast-offer?tpcc=padlock. Hosted on Acast. See acast.com/privacy for more information.

Dr. Olle Johansson is a retired professor of basic and applied neuroscience from the Karolinska Institute and the Royal Institute of Technology in Stockholm, Sweden and he's considered a world-leading authority in electromagnetic fields and their biological effects on living organisms.In this conversation with Dr. Johansson we discuss:His first (coincidental) introduction into the issue of EMF exposureThe troubling scientific findings on EMF exposureThe similarities to having an allergyFunctional impairment electrohypersensitivityThe challenge of holding anyone accountableTools and tests to help protect yourself and your family...and more!Learn more about Dr. Johansson and his work and how you can help support it at https://research.radiation.dk/.For those interested in exploring some of the meters mentioned in the episode, learn more here:Cornet ED98QPro5G (0.1-8GHz) Quad-Mode Electrosmog MeterEMRSS Cornet ED88TPlus 5G Latest Version Tri Mode Meter EMF/RF Detector/Acoustic and Low Frequency Gaussmeter and Electric Field Meter with Sound Signature and DataloggerSupport Terrain Theory on Patreon! Our recently-launched member platform gives you access to a ton of free & exclusive content. Check it out: https://www.patreon.com/TerrainTheoryTerrain Theory episodes are not to be taken as medical advice. You are your own primary healthcare provider.If you have a Terrain Transformation story you would like to share, email us at ben@terraintheory.net.Learn more at www.terraintheory.netMusic by Chris Merenda

The Occasional Human Sacrifice: Medical Experimentation and the Price of Saying No (Norton, 2024) is an intellectual inquiry into the moral struggle that whistleblowers face, and why it is not the kind of struggle that most people imagine. Carl Elliott is a bioethicist at the University of Minnesota who was trained in medicine as well as philosophy. For many years he fought for an external inquiry into a psychiatric research study at his own university in which an especially vulnerable patient lost his life. Elliott's efforts alienated friends and colleagues. The university stonewalled him and denied wrongdoing until a state investigation finally vindicated his claims. His experience frames the six stories in this book of medical research in which patients were deceived into participating in experimental programs they did not understand, many of which had astonishing and well-concealed mortality rates. Beginning with the public health worker who exposed the Tuskegee Syphilis Study and ending with the four physicians who in 2016 blew the whistle on lethal synthetic trachea transplants at the Karolinska Institute, Elliott tells the extraordinary stories of insiders who spoke out against such abuses, and often paid a terrible price for doing the right thing. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

The Occasional Human Sacrifice: Medical Experimentation and the Price of Saying No (Norton, 2024) is an intellectual inquiry into the moral struggle that whistleblowers face, and why it is not the kind of struggle that most people imagine. Carl Elliott is a bioethicist at the University of Minnesota who was trained in medicine as well as philosophy. For many years he fought for an external inquiry into a psychiatric research study at his own university in which an especially vulnerable patient lost his life. Elliott's efforts alienated friends and colleagues. The university stonewalled him and denied wrongdoing until a state investigation finally vindicated his claims. His experience frames the six stories in this book of medical research in which patients were deceived into participating in experimental programs they did not understand, many of which had astonishing and well-concealed mortality rates. Beginning with the public health worker who exposed the Tuskegee Syphilis Study and ending with the four physicians who in 2016 blew the whistle on lethal synthetic trachea transplants at the Karolinska Institute, Elliott tells the extraordinary stories of insiders who spoke out against such abuses, and often paid a terrible price for doing the right thing. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/history

The Occasional Human Sacrifice: Medical Experimentation and the Price of Saying No (Norton, 2024) is an intellectual inquiry into the moral struggle that whistleblowers face, and why it is not the kind of struggle that most people imagine. Carl Elliott is a bioethicist at the University of Minnesota who was trained in medicine as well as philosophy. For many years he fought for an external inquiry into a psychiatric research study at his own university in which an especially vulnerable patient lost his life. Elliott's efforts alienated friends and colleagues. The university stonewalled him and denied wrongdoing until a state investigation finally vindicated his claims. His experience frames the six stories in this book of medical research in which patients were deceived into participating in experimental programs they did not understand, many of which had astonishing and well-concealed mortality rates. Beginning with the public health worker who exposed the Tuskegee Syphilis Study and ending with the four physicians who in 2016 blew the whistle on lethal synthetic trachea transplants at the Karolinska Institute, Elliott tells the extraordinary stories of insiders who spoke out against such abuses, and often paid a terrible price for doing the right thing. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

In this episode of the Heart podcast, Digital Media Editor, Professor James Rudd, is joined by Prof Finn Akerstrom from Karolinska Institute in Stockholm, Sweden. They discuss his observational study on AF ablation and mortality. If you enjoy the show, please leave us a podcast review wherever you get your podcasts - it's really helpful. Link to published paper: https://heart.bmj.com/content/110/3/163

Olle Johansson, associate professor, head of the Experimental Dermatology Unit, Department of Neuroscience, at the Karolinska Institute (famous for its Nobel Prize in Physiology or Medicine) in Stockholm, Sweden, is a world-leading authority in the field of EMF radiation and health effects.   He has published more than 500 original articles, reviews, book chapters and conference reports within the field of basic and applied neuroscience.   https://stop5g.cz/us/prof-olle-johansoon/   / / / / / /   Today's podcast is in association NutraHealth365 who manufacture a superb high potency Vitamin D3 supplement called ImmuneX365. As we approach winter, your body's defences are under constant attack from flu, respiratory diseases and the common cold. So now, more than ever, is it essential that you have a robust immune system and as we all know, Vitamin D3 plays an essential role in this. ImmuneX365 is an exclusive and unique formulation that combines effective levels of Vitamins D3, C, and K2, as well as Zinc and Quercetin.   This unique combination of nutrients ensures efficient bioavailability of D3, thereby giving your immune system an optimum boost. Take back your health with just two capsules of ImmuneX365 every day.   For your peace of mind, all NutraHealth365 orders come with free two day tracked delivery, Go to http://NutraHealth365.com to get yours now."    That's http://NutraHealth365.com.   —   Following on from the grand success of last year's Delingpod event in London with guest Maajid Nawaz and earlier this year with the great Neil Oliver - James has decided to bring his popular Delingpod LIVE UP NORTH this time with his extremely special guest, David Icke! Please note that the exact location of the event will be disclosed within 48 hours of the date. Link to buy tickets: https://www.tickettailor.com/events/thedelingpodlive/1012094?fbclid=IwAR1C_3Vldrr8w0ifxPL81j-6qiQa1c6QB3BZ1lFfxcoDSiLooSCeoDbU--g   ↓ ↓ ↓   If you need silver and gold bullion - and who wouldn't in these dark times? - then the place to go is The Pure Gold Company. Either they can deliver worldwide to your door - or store it for you in vaults in London and Zurich. You even use it for your pension. Cash out of gold whenever you like: liquidate within 24 hours. https://bit.ly/James-Delingpole-Gold   / / / / / /   Earn interest on Gold: https://monetary-metals.com/delingpole/   / / / / / /   Buy James a Coffee at: https://www.buymeacoffee.com/jamesdelingpole Support James' Writing at: https://delingpole.substack.com Support James monthly at: https://locals.com/member/JamesDelingpole?community_id=7720