Podcast appearances and mentions of aparna krishnan

Hello and welcome to this special episode of Let's Talk Rare: The Life Science Podcast as we celebrate 5 years of bringing you the podcast that is now the number one life science podcast across all platforms. We at Partners 4 Access want to thank every single one of our 35,000 subscribers and all the guests who have graced the podcast from the bottom of our hearts, we would not have gotten here without you.  A special episode calls for special guests, and joining us today are our in-house expert and Managing Partner at P4A, Sophie Schmitz, our host from 2018-2021, Aparna Krishnan, and Prasan Subedi, Access Strategy Team Lead at Pfizer. Together, we walk down memory lane and relive the high points and challenges of the past five years, and share insights on rare diseases and cell and gene therapies. Aparna Krishnan Bio: Aparna has over 10 years of experience in the pharmaceutical and healthcare industry. As part of the senior leadership team, her primary focus is on strategic corporate engagement, legal, financial operations, and human resources. She has previously worked as Manager of Life Sciences at IHS Markit and as Consultant at Parexel's Commercialization unit, among others specializing in market access, pricing, and reimbursement. Sophie Schmitz Bio: Sophie is the managing partner at Partners 4 Access, a company that believes in a sustainable rare disease world, which means helping our clients unlock the true opportunity of orphan drugs and ATMPs. Her 20+ year career spans various disease areas and medical devices, successfully supporting the strategy development and operationalization for orphan drugs. She brings a wealth of commercial and access experience across orphan and cell and gene therapies to the benefit of clients. She plays an active role in advising clients on price and market access strategies, with the ultimate goal of optimizing fair access for all stakeholders in rare diseases.

Aparna Krishnan is a Thiel Fellow and the co-founder and CTO of Opyn. Her previous experience includes working on mechanism labs, conducting open-source blockchain research. Furthermore, her CV boasts Head of Education and Executive VP at Blockchain at Berkeley and the founding of the Education Department at Blockchain at Berkeley.

A ‘token’ can represent almost anything in Ethereum, according to Ethereum.org: Lottery tickets, points in an online platform, fiat currency, and much more. These tokens must follow a standard called ECR-20 to have the same type and value of any other token, and behave just like the ETH.   The platform Opyn lets users buy and The post OPYN: DeFi Options Trading with Aparna Krishnan appeared first on Software Engineering Daily.

A ‘token’ can represent almost anything in Ethereum, according to Ethereum.org: Lottery tickets, points in an online platform, fiat currency, and much more. These tokens must follow a standard called ECR-20 to have the same type and value of any other token, and behave just like the ETH.   The platform Opyn lets users buy and The post OPYN: DeFi Options Trading with Aparna Krishnan appeared first on Software Engineering Daily.

A ‘token' can represent almost anything in Ethereum, according to Ethereum.org: Lottery tickets, points in an online platform, fiat currency, and much more. These tokens must follow a standard called ECR-20 to have the same type and value of any other token, and behave just like the ETH.   The platform Opyn lets users buy and

A ‘token' can represent almost anything in Ethereum, according to Ethereum.org: Lottery tickets, points in an online platform, fiat currency, and much more. These tokens must follow a standard called ECR-20 to have the same type and value of any other token, and behave just like the ETH.   The platform Opyn lets users buy and The post OPYN: DeFi Options Trading with Aparna Krishnan appeared first on Software Engineering Daily.

Alexis Gauba and Aparna Krishnan, co-founder of Opyn, join the podcast to discuss their DeFi platform. Opyn allows users to hedge ETH (and other token) risks by buying or selling call/put options on chain. By leveraging this technology, those who deposit assets in DeFi can also use it to take out insurance on those deposits. Alexis and Aparna give a great overview of how Opyn works and speak to some of the very interesting use cases that it could be leveraged for in the future.

Trustless options protocol Opyn is the latest in decentralized finance innovations and already attracting over $1M in value locked. Co-founder Aparna Krishnan (@aparnalocked) joins me in discussing: How onchain put options are priced Why Opyn can also be a volatility oracle for DeFi How Opyn compares to competitors Hegic and Nexus Mutual Host: Jason Choi (@MrJasonChoi). If you enjoyed the show, consider tipping! This show is not financial advice. BTC: 3EFSLnPpme6Lo6DynN1bVV9owooueFvEmJ ETH: 0xdec40AA30B9C562aB4b839529BfC290C1B5Da61E  ****** Resources: Subscribe to my essays here: jasonchoi.substack.com ****** Musical credits: Transition track: "BHANGER" by Phortissimo. Used with permission Outro track: "LEMMiNO - Infinity [Chill]" is released under a Creative Commons license (BY-SA) 4.0 Music provided by BreakingCopyright: https://youtu.be/uweorwa3q34 Disclaimer: Jason Choi is an investor at Spartan Capital, the hedge fund arm of The Spartan Group. All opinions expressed by Jason and podcast guests are solely their own opinions and do not reflect the opinion of The Spartan Group and any of its subsidiaries and personnel. This podcast is for information purposes only and should not be relied upon as a basis for investment decisions. 

On Today's Episode of Let's Talk Bitcoin... In our first segment, we'll join Andreas Antonopoulos, Stephanie Murphy, Jonathan Mohan, and Adam B. Levine for a look at the varied approaches being used to connect your Bitcoin to credit card style ease-of-use. After the break, guest host Alex Gladstein and Adam B. Levine sit down once again for another installment of LTB Global Voices. This time we talk with Aparna Krishnan about the unique situation brewing in India today. Today's episode was sponsored by Edge.app and BlockchainTraining.org --- Highlights: “It's almost as if the entire mechanism is designed to put you into debt, hopefully to get you to a point where you end up racking up fees to enrich some group of bankers..as if the entire system is designed to not only make you a debt slave, but make sure that you work for a wage salaried position to a giant corporation.” - Andreas Antonopoulos “..if anyone represents themselves as insured, you have to really look into what they mean. I feel like a lot of people are conflating one type of insurance with the other when they're making financial decisions about where they put their money. So when it comes to collateralized lending and engaging in margin, that's the whole point that crypto was trying to escape is that type of understanding of finance” - Jonathan Mohan “..when you say something like “banking the unbanked,” it's important to understand why people are unbanked in the first place. One thing that I found really interesting in India was that a large number of these people who are unbanked don't know how to use the existing financial system. It's not that they don't have access to financial systems.” - Aparna Krishnan --- Episode 404 featured content from Andreas Antonopoulos, Stephanie Murphy, Jonathan Mohan, Adam B. Levine, Alex Gladstein, and Aparna Krishnan. This episode featured music by Jared Rubens and General Fuzz, with editing by Steven and Adam. Any questions or comments? You can either email adam@letstalkbitcoin.com, or now leave a voice message directly through your anchor.fm app, or on the new show page at ltbshow.com Image credit: CC-SA http://www.picpedia.org/credit-cards/credit-cards09.html

Aparna Krishnan is head of education at Blockchain at Berkeley and co-founder of Mechanism Labs, an open source blockchain research lab. Earlier this year, Aparna was awarded a scholarship by the DFINITY Foundation for Mechanism Labs’ research into consensus mechanisms. This episode is essentially a primer for advanced discussion of consensus in decentralized networks. https://mechanismlabs.io/ https://github.com/aparnakr https://twitter.com/aparnalocked https://medium.com/@aparnalocked Aparna Krishnan Co-founder mechanism labs open source research lab All work and research is on Github Telegram: @mechanism_labs Co-founder of the education team at Blockchain Berkeley Consensus researcher Teaches executive education courses Consensus Proof of Work Proof of Stake Old Field History Cynthia Dwork developed stronger adversarial models Did not have many applications Blockchain has brought cryptography and consensus into the mainstream eye Protocols DFINITY Tendermint Bitcoin Focus has been on proof of stake protocols Mining may not be sustainable Long term sustainabilities and lack of externalities is important Proof of stake offers efficiently As does proof of elapsed time and proof of space and time Consensus Sybil control Coming to agreement relies on traditional consensus PoS, PoW refer to the sybil control mechanism PoS - Putting down capital Financial penalty for misbehavior Token holders are participants PoW - burning energy One cpu, one vote No connection between token custody and rewards P o Elapsed Time Proof of Authority placing reputation A cost of playing ball Traditional Consensus (PBFT) No concept of probabilistic finality All honest nodes come to final agreement Closed, permissioned Blockchain All nodes may with a high degree of probability agree A probabilistic guarantee Longest Chain Rule Longest sequence of blocks is the Ethereum Ghost Can be attacked by a stealthy entity Open, permissionless, decentralized Inefficient Node churn Better liveness properties Early PoS 2013 PeerCoin NXT Bitshares Primitive State grinding attack vulnerable Randomness derived from blockhashes New Generation DFINITY Uses threshold relay decentralized randomness Tendermint Round robin Has social layer fallback Ethereum Casper Thunderella Algorand Hides the block creator until the block has been created In Tendermint a minority below the assumption cannot break finality In Bitcoin >10% can change the finality through threatening to censor Hard to get both economic and cryptographic security. Not clear that bribing and collusion attacks have been solved. No protocols have shown sophisticated economic models. Mechanism Labs Focussing on incentive schemes What does it mean to have a stable, scalable protocol Scalability Proof of Replication Recent work with Verifiable delay functions In commit/reveal schemes there is an opportunity to manipulate by giving only one person the ability to reveal the randomness Verifiable delay functions allow anyone to reveal the randomness ASIC resistance because not parallelizable

Aparna Krishnan talks about her research company Mechanism Labs, mentoring women in blockchain at She(256), dealing with the bro culture in the blockchain space, her experience growing up under Internet censorship and how it shaped her interest in cryptography, building up the education department at Blockchain at Berkeley, what she observed teaching introductions to the technology, takeaways from her Thiel Fellowship, and much more. Aparna is a Thiel Fellow and the co-founder of Mechanism Labs, an open source blockchain research lab. She studied computer science at the University of California, Berkeley, works on cryptography research and was the Head of Education and Executive VP at Blockchain at Berkeley where she founded the Education Department. She has taught the world's largest university accredited blockchain course, and she is a mentor at She(256), a movement to increase diversity and break down barriers to entry in the blockchain space. Aparna Krishnan: https://github.com/aparnakr, https://twitter.com/aparnalocked, https://medium.com/@aparnalocked, https://www.linkedin.com/in/aparna-krishnan Mechanism Labs: https://mechanismlabs.io, https://github.com/Mechanism-Labs, https://medium.com/mechanism-labs  She(256):https://www.she256.io, https://twitter.com/SHE_256  Thiel Fellowship: https://thielfellowship.org  Blockchain at Berkeley: https://blockchain.berkeley.edu, https://twitter.com/CalBlockchain Blockchain at Berkeley YouTube channel: https://www.youtube.com/channel/UC5sgoRfoSp3jeX4DEqKLwKg/videos  Also mentioned in the episode: Manush Movahedi: www.cs.yale.edu/homes/movahedi, https://scholar.google.com/citations?user=3iOahLIAAAAJ&hl=en  Elaine Shi: http://elaineshi.com, https://twitter.com/ElaineRShi  The Blockchain and Us newsletter To stay up to date about what blockchain pioneers, innovators and entrepreneurs from all around the world think about the future of this space, sign up for the newsletter on http://www.theblockchainandus.com.

In this episode Erik talks to Aparna Krishnan (@aparnalocked), co-founder of Mechanism Labs and Haseeb Qureshi (@hosseeb), GP at MetaStable Capital. They discuss a number of themes around Aparna's research paper, talk about what it means to find consensus, and they go through the various protocols that exist now to try and do that. They also talk about what kinds of applications these various protocols could have.They explain what a block is, what proof of work and proof of stake mean, and why the longest chain rule could be a potential pitfall for Bitcoin.Reading List For This Episode:Non- Technical:- MultiChain's blog- Ashley Lannquist’s blog- https://www.jbs.cam.ac.uk/fileadmin/user_upload/research/centres/alternative-finance/downloads/2018-08-20-conceptualising-dlt-systems.pdf- https://eprint.iacr.org/2017/375.pdfTechnical (new to the space):- cryptoeconomics.study- Vitalik’s blog posts- Mechanism Labs blog, GitHub- Blockchain at Berkeley blog and educational contentLooking to get into research: - Consensus: https://github.com/Mechanism-Labs/MetaAnalysis-of-Alternative-Consensus-Protocols/blob/master/MetaAnalysis.pdf, https://arxiv.org/pdf/1711.03936.pdf- Privacy/ Security: https://arxiv.org/pdf/1706.00916.pdf- Smart Contracts: https://eprint.iacr.org/2018/192.pdf- IC3! Thanks for listening — if you like what you hear, please review us on your favorite podcast platform. Check us out on the web at villageglobal.vc or get in touch with us on Twitter @villageglobal.Venture Stories is brought to you by Village Global, is hosted by co-founder and partner, Erik Torenberg and is produced by Brett Bolkowy.

In this episode Erik talks to Aparna Krishnan (@aparnalocked), co-founder of Mechanism Labs and Haseeb Qureshi (@hosseeb), GP at MetaStable Capital. They discuss a number of themes around Aparna's research paper, talk about what it means to find consensus, and they go through the various protocols that exist now to try and do that. They also talk about what kinds of applications these various protocols could have.They explain what a block is, what proof of work and proof of stake mean, and why the longest chain rule could be a potential pitfall for Bitcoin.Reading List For This Episode:Non- Technical:- MultiChain's blog- Ashley Lannquist’s blog- https://www.jbs.cam.ac.uk/fileadmin/user_upload/research/centres/alternative-finance/downloads/2018-08-20-conceptualising-dlt-systems.pdf- https://eprint.iacr.org/2017/375.pdfTechnical (new to the space):- cryptoeconomics.study- Vitalik’s blog posts- Mechanism Labs blog, GitHub- Blockchain at Berkeley blog and educational contentLooking to get into research: - Consensus: https://github.com/Mechanism-Labs/MetaAnalysis-of-Alternative-Consensus-Protocols/blob/master/MetaAnalysis.pdf, https://arxiv.org/pdf/1711.03936.pdf- Privacy/ Security: https://arxiv.org/pdf/1706.00916.pdf- Smart Contracts: https://eprint.iacr.org/2018/192.pdf- IC3! Thanks for listening — if you like what you hear, please review us on your favorite podcast platform. Check us out on the web at villageglobal.vc or get in touch with us on Twitter @villageglobal.Venture Stories is brought to you by Village Global, is hosted by co-founder and partner, Erik Torenberg and is produced by Brett Bolkowy.

We speak with Alexis Gauba & Aparna Krishnan, co-founders of Mechanism Labs, an open source set of experiments focused on pushing forward research in the blockchain space. We discuss their research into alternative consensus protocols, and they give some advice for other women entering the blockchain space. Full show notes: https://thecoinoffering.com/podcast/s02/e10-alexis-gauba-aparna-krishnan/

This week the P4A team discuss key advancements in oncology treatments - a genetic test indicating whether chemotherapy is beneficial in a particular breast cancer patient group and successful results of an immunotherapy using T cells in an advanced breast cancer patient. In addition, news involving a potential new sickle cell therapy under development. Presenter: Max Rex Contributors: Alison Kneen and Aparna Krishnan

In its very first podcast of Rare Disease, Cell & Gene Therapy Weekly RoundUp, P4A discusses the US FDA's accelerated regulatory process for gene therapy; President's Trump's proposed drug pricing plan; the European Commission's proposal to amend SPC; the NHS England budget ringfencing; Irish government's attempt to trim the HSE and the new GDPR laws. Max Rex hosts with contributions from Aparna Krishnan, Corporate Affairs Lead and Alison Kneen, Vice President, International Operations.