Podcast appearances and mentions of meta analysis

AEM Podcast host Ken Milne, MD, and guest skeptic Suchismita Datta, MD, interview lead author Rachel E. Solnick, MD, MSc. Learn more in the accompanying Hot Off the Press article available in The Skeptics' Guide to Emergency Medicine.

We're witnessing the early stages of a paradigm shift, as artificial intelligence is beginning to impact virtually every aspect of healthcare, from research to patient care. And there's much, much more to come.    This week, Dr. Brad Willingham, the Director of MS Research at Shepherd Center in Atlanta, joins me to discuss how AI will impact MS patient care. We'll also share the encouraging results from a Phase 2 open-label extension study for Fenebrutinib, an investigational disease-modifying therapy. We'll tell you about study results that show exercise interventions that follow physical activity guidelines for MS can have a significant impact on MS-related depression. And we're sharing the results of a study that illustrate what can happen when you delay starting a disease-modifying therapy. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: How AI will impact MS patient care  :22 Fenebrutinib shows positive results after one-year extension study  1:33 MS-related depression can be significantly eased through exercise intervention that follows physical activity guidelines for MS  3:36 What happens when you delay starting disease-modifying therapy?   8:46 Dr. Brad Willingham discusses how artificial intelligence is impacting all aspects of healthcare  14:29 Share this episode  33:18 Have you downloaded the free RealTalk MS app?  33:38 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/413 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com Become an MS Activist https://nationalmssociety.org/advocacy STUDY: Safety and Efficacy of Fenebrutinib in Relapsing Multiple Sclerosis (FENopta): A Multicentre, Double-Blind, Randomised, Placebo-Controlled, Phase 2 Trial and Open-Label Extension https://thelancet.com/journals/laneur/article/PIIS1474-4422(25)00174-7/abstract?rss=yes STUDY: Effects of Meeting Exercise Guidelines on Depression and Anxiety in Multiple Sclerosis: A Systematic Review and Meta-Analysis https://tandfonline.com/doi/full/10.1080/09593985.2025.2518261 Exercise and Physical Activity Recommendations for ALL People with MS  https://nationalmssociety.org/news-and-magazine/news/exercise-and-physical-activity-recommend STUDY: Delayed Access and Adherence are Real-World Challenges That Compromise Effectiveness of Natalizumab in Multiple Sclerosis https://sciencedirect.com/science/article/abs/pii/S2211034825003694 Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 413 Guest: Dr. Brad Willingham Privacy Policy

In this episode of RAPM Focus, Editor-in-Chief Brian Sites, MD, discusses the use of buprenorphine for acute pain management with Thomas Hickey, MD, MS, following the February 2025 publication of “Buprenorphine versus full agonist opioids for acute postoperative pain management: a systematic review and meta-analysis of randomized controlled trials.” Dr. Hickey is full-time staff at the West Haven VA where he is medical director of preoperative evaluation and the PACU, and site director for the anesthesiology residency. Within the VA, he is chairman of the VA New England Healthcare System committee on preoperative evaluation and ERAS, co-chair of the VA's national pain/opioid consortium for research workgroup on perioperative management of medications for opioid use disorder, and a member of the National Anesthesia Program Acute Pain Management Committee. He is board certified in both anesthesiology and addiction medicine. His research interests focus on the overlap between addiction medicine and acute pain management, particularly on the use of buprenorphine for acute pain management. He and his wife are kept busy by their three kids and all their activities. *The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice, and it is not intended to function as a substitute for a healthcare practitioner's judgement, patient care, or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others. Podcast and music produced by Dan Langa. Find us on X @RAPMOnline, LinkedIn @Regional Anesthesia & Pain Medicine, Facebook @Regional Anesthesia & Pain Medicine, and Instagram @RAPM_Online.

Heath reviews his first tournament with the Wrath of the Rock Detachment. If you want to learn more about Dank Lists Wargaming then follow us on our social medias listed below and subscribe here:Email: danklistswargaming@gmail.comFacebook: https://www.facebook.com/danklists/Instagram: https://www.instagram.com/danklistswargaming/Twitch: https://www.twitch.tv/danklistswargamingTwitter: https://twitter.com/DankListsWebsite: https://danklistswargaming.wixsite.com/danklistsMDF Terrain by Laser Craft Workshop: https://lasercraftworkshop.com/Video made using Da Vinci 20.Credit: "Music: https://www.purple-planet.com'For written Meta Analysis, please visit: https://40kangelskeep.blogspot.com/

Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3680: Benjamin Hardy explores the profound impact of relationships on our health, happiness, and personal growth, drawing from a 75-year Harvard study and other compelling research. You'll discover how love, gratitude, and living for something beyond yourself can be powerful drivers of resilience, purpose, and emotional well-being. Read along with the original article(s) here: https://medium.com/thrive-global/this-75-year-harvard-study-reveals-the-secret-to-happiness-and-success-3cf0002510fe Quotes to ponder: “The clearest message that we get from this 75-year study is this: Good relationships keep us happier and healthier. Period.” “The biggest predictor of your happiness and fulfillment overall in life is, basically, love.” “You can give without loving, but you can't love without giving.” Episode references: Meta-Analysis on Social Relationships and Mortality Risk: https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1000316 Dr. Gabor Maté Official Website: https://drgabormate.com John Wooden Quotes: https://www.brainyquote.com/quotes/john_wooden_104927 Viktor Frankl, Man's Search for Meaning: https://www.amazon.com/Mans-Search-Meaning-Viktor-Frankl/dp/0807014273 What Makes a Good Life? Lessons from the longest study on happiness – Robert Waldinger TED Talk: https://www.ted.com/talks/robert_waldinger_what_makes_a_good_life_lessons_from_the_longest_study_on_happiness Learn more about your ad choices. Visit megaphone.fm/adchoices

Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3680: Benjamin Hardy explores the profound impact of relationships on our health, happiness, and personal growth, drawing from a 75-year Harvard study and other compelling research. You'll discover how love, gratitude, and living for something beyond yourself can be powerful drivers of resilience, purpose, and emotional well-being. Read along with the original article(s) here: https://medium.com/thrive-global/this-75-year-harvard-study-reveals-the-secret-to-happiness-and-success-3cf0002510fe Quotes to ponder: “The clearest message that we get from this 75-year study is this: Good relationships keep us happier and healthier. Period.” “The biggest predictor of your happiness and fulfillment overall in life is, basically, love.” “You can give without loving, but you can't love without giving.” Episode references: Meta-Analysis on Social Relationships and Mortality Risk: https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1000316 Dr. Gabor Maté Official Website: https://drgabormate.com John Wooden Quotes: https://www.brainyquote.com/quotes/john_wooden_104927 Viktor Frankl, Man's Search for Meaning: https://www.amazon.com/Mans-Search-Meaning-Viktor-Frankl/dp/0807014273 What Makes a Good Life? Lessons from the longest study on happiness – Robert Waldinger TED Talk: https://www.ted.com/talks/robert_waldinger_what_makes_a_good_life_lessons_from_the_longest_study_on_happiness Learn more about your ad choices. Visit megaphone.fm/adchoices

Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3680: Benjamin Hardy explores the profound impact of relationships on our health, happiness, and personal growth, drawing from a 75-year Harvard study and other compelling research. You'll discover how love, gratitude, and living for something beyond yourself can be powerful drivers of resilience, purpose, and emotional well-being. Read along with the original article(s) here: https://medium.com/thrive-global/this-75-year-harvard-study-reveals-the-secret-to-happiness-and-success-3cf0002510fe Quotes to ponder: “The clearest message that we get from this 75-year study is this: Good relationships keep us happier and healthier. Period.” “The biggest predictor of your happiness and fulfillment overall in life is, basically, love.” “You can give without loving, but you can't love without giving.” Episode references: Meta-Analysis on Social Relationships and Mortality Risk: https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1000316 Dr. Gabor Maté Official Website: https://drgabormate.com John Wooden Quotes: https://www.brainyquote.com/quotes/john_wooden_104927 Viktor Frankl, Man's Search for Meaning: https://www.amazon.com/Mans-Search-Meaning-Viktor-Frankl/dp/0807014273 What Makes a Good Life? Lessons from the longest study on happiness – Robert Waldinger TED Talk: https://www.ted.com/talks/robert_waldinger_what_makes_a_good_life_lessons_from_the_longest_study_on_happiness Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of Quah (Q & A), Sal, Adam & Justin answer four Pump Head questions drawn from last Sunday's Quah post on the @mindpumpmedia Instagram page.  Mind Pump Fit Tip: 9 Reasons Getting Stronger is the Best Physical Pursuit. (1:58) The different stages of raising a child. (24:07) The ultimate nootropic, methylene blue. (42:27) Peeing outside. (48:16) Sauna/hot tub and sodium. (50:01) When your hormones are feeling REALLY good. (52:06) Kids say the darndest things. (56:00) #Quah question #1 – What are your thoughts on day-long workouts? I work from home most days, and I like to spread my workout throughout the day. (57:45) #Quah question #2 – How to break through plateaus? I've been stuck on preacher curls, among other exercises, for two months. (1:02:39) #Quah question #3 – I'm about as beginner as a beginner can get when it comes to lifting, to the point that I don't know how to get started, and I have no clue what my baseline is. Do I just go to the weight bench and throw on some plates? What is the very first step for someone who has never lifted? (1:04:40) #Quah question #4 – You always mention going for a walk after a meal. Does going before eating have the same benefits or not? (1:09:09) Related Links/Products Mentioned Visit Troscriptions for the exclusive offer for Mind Pump listeners! **Promo code MINDPUMP for 10% off your first order. ** Get your free Sample Pack with any “drink mix” purchase! Find your favorite LMNT flavor, or share it with a friend. Try LMNT risk-free. If you don't like it, give it away to a salty friend and we'll give you your money back, no questions asked! Visit DrinkLMNT.com/MindPump July Special: MAPS Split or Anabolic Metabolism Bundle 50% off! ** Code JULY50 at checkout ** Association of Grip Strength With Risk of All-Cause Mortality, Cardiovascular Diseases, and Cancer in Community-Dwelling Populations: A Meta-analysis of Prospective Cohort Studies Muscular Strength as a Predictor of All-Cause Mortality in an Apparently Healthy Population: A Systematic Review and Meta-Analysis of Data From Approximately 2 Million Men and Women Exercise interventions for older adults: A systematic review of meta-analyses Association of Efficacy of Resistance Exercise Training With Depressive Symptoms: Meta-analysis and Meta-regression Analysis of Randomized Clinical Trials Adherence to Strength Training and Lower Rates of Sports Injury in Contact Sports: A Systematic Review and Meta-analysis Parenting: Getting It Right Visit Paleovalley for an exclusive offer for Mind Pump listeners! ** Discount is now automatically applied at checkout: 15% off your first order! ** Mind Pump # 2552: From Plateau to PR… How to Break Through Strength Barriers Mind Pump # 2385: Five Reasons Why You Should Hire a Trainer Mind Pump Podcast – YouTube Mind Pump Free Resources People Mentioned LAUREN FITZ, M.D. (@drlaurenfitz) Instagram    

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Incidence of Stroke in Adults With Congenital Heart Disease: A Systematic Review and Meta-Analysis.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Effect of Frailty on Cardiovascular Clinical Trials: A Systematic Review and Meta-Analysis.

***JOIN THE NEXT MASTER YOUR FASTING CHALLENGE THAT STARTS August 13th, 2025!*** We'll GUIDE you on how to FAST to LOSE FAT for good, and use ‘fast cycling' to achieve uncommon results! REGISTER HERE! Click the link for DATES, DETAILS, and FAQs! This episode reveals game-changing research from a meta-analysis of 30 randomized controlled trials with 1,341 participants that will transform how you approach intermittent fasting. Dr. Scott and Tommy break down the shocking discovery that fasting without calorie counting produces DOUBLE the weight loss compared to fasting while tracking calories - 6.22 pounds versus 3.22 pounds respectively. More importantly, only the non-calorie counting fasting group saw significant improvements in fasting glucose (8-point drop), insulin levels (6.3 point reduction), cholesterol, triglycerides, and blood pressure, while the calorie-controlled group showed no consistent metabolic improvements. Learn why obsessing over hitting your daily calorie targets during eating windows actually sabotages your fasting benefits by potentially causing you to overeat, creating exaggerated blood sugar spikes, and interfering with natural hunger and satiety cues. The hosts explain how fasting naturally creates caloric restriction through appetite regulation and circadian biology optimization, making manual calorie counting unnecessary and counterproductive. Discover why the simplification approach - choosing an eating window and sticking to it consistently while prioritizing protein - outperforms complicated tracking methods for sustainable weight loss and metabolic health. This episode provides the scientific validation that fasting works best when you trust the process and let your body's natural mechanisms guide food intake, rather than forcing predetermined calorie targets. Essential listening for anyone frustrated with calorie counting approaches or wondering whether they need to track macros while intermittent fasting. The research conclusively shows: fasting simplifies everything while delivering superior results. ⁠⁠Take the NEW FASTING PERSONA QUIZ! - The Key to Unlocking Sustainable Weight Loss With Fasting!⁠⁠⁠ Resources and Downloads: ⁠⁠⁠SIGN UP FOR THE DROP OF THE ULTIMATE GUIDE TO BLOOD SUGAR CONTROL⁠⁠⁠ ⁠⁠⁠GRAB THE OPTIMAL RANGES FOR LAB WORK HERE! - NEW RESOURCE! ⁠ ⁠⁠⁠FREE RESOURCE - DOWNLOAD THE NEW BLUEPRINT TO FASTING FOR FAT LOSS!⁠⁠⁠ ⁠⁠⁠SLEEP GUIDE DIRECT DOWNLOAD⁠⁠⁠ ⁠⁠⁠DOWNLOAD THE FASTING TRANSFORMATION JOURNAL HERE!⁠⁠⁠ Partner Links: Get your⁠⁠⁠ FREE BOX OF LMNT⁠⁠⁠ hydration support for the perfect electrolyte balance for your fasting lifestyle with your first purchase⁠⁠⁠ here!⁠⁠⁠ Get ⁠⁠⁠25% off a Keto-Mojo⁠⁠⁠ blood glucose and ketone monitor (discount shown at checkout)! ⁠⁠⁠Click here!⁠⁠⁠ Our Community: Let's continue the conversation. Click the link below to JOIN the ⁠⁠⁠Fasting For Life Community⁠⁠⁠, a group of like-minded, new, and experienced fasters! The first two rules of fasting need not apply! If you enjoy the podcast, please tap the stars below and consider leaving a short review on Apple Podcasts/iTunes. It takes less than 60 seconds, and it helps bring you the best original content each week. We also enjoy reading them! Article Links: https://academic.oup.com/nutritionreviews/advance-article/doi/10.1093/nutrit/nuaf053/8121825

Heath and Bailey review the balance data slate and the new Wrath of the Rock Detachment.If you want to learn more about Dank Lists Wargaming then follow us on our social medias listed below and subscribe here:Email: danklistswargaming@gmail.comFacebook: https://www.facebook.com/danklists/Instagram: https://www.instagram.com/danklistswargaming/Twitch: https://www.twitch.tv/danklistswargamingTwitter: https://twitter.com/DankListsWebsite: https://danklistswargaming.wixsite.com/danklistsMDF Terrain by Laser Craft Workshop: https://lasercraftworkshop.com/Video made using Da Vinci 20.Credit: "Music: https://www.purple-planet.com'For written Meta Analysis, please visit: https://40kangelskeep.blogspot.com/

Hoje recebemos a convidada Dra. Christiane Rolim de Moura que é formada em Medicina pela Faculdade de Ciências Médicas da Santa Casa de São Paulo e possui residência médica, mestrado, doutorado e pós-doutorado em Oftalmologia pela Escola Paulista de Medicina – UNIFESP.  Atualmente, é pós-doutoranda no Instituto de Psicologia da USP e realizou especializações no Setor de Glaucoma do Doheny Eye Institute, em Los Angeles, e no Children's Hospital of Los Angeles. Atua como médica oftalmologista na Reitoria da UNIFESP e ocupa o cargo de vice-presidente da Sociedade Brasileira de Oftalmologia Pediátrica (SBOP) na gestão 2023-2025.Neste episódio a Dra Julia Rossetto e a Dra Christiane Rolim discutem sobre esta revisão sistemática e meta-análise de dose-resposta de 45 estudos envolvendo 335.524 indivíduos que revelou uma associação significativa de entre o tempo de tela e as chances de miopia. Também falamos sobre: o que é uma meta-análise e sua importância na pesquisa científica; os principais pontos que devemos observar ao ler uma meta-análise para avaliar a robustez de suas conclusões; uma explicação detalhada de como foi realizada a meta-análise em discussão.Material Suplementar:Ha A, Lee YJ, Lee M, Shim SR, Kim YK. Digital Screen Time and Myopia: A Systematic Review and Dose-Response Meta-Analysis. JAMA Netw Open. 2025 Feb 3;8(2):e2460026. doi: 10.1001/jamanetworkopen.2024.60026. PMID: 39982728; PMCID: PMC11846013.Gostou deste episódio? Ouça também:#SBOPCAST EP 43 – Journal Club: Artigo PEDIG: atropina 0,01 não funciona para evitar progressão da miopia?  - Playlist Miopia 

Sensorimotor Dysfunction & the Cervical Spine: What Clinicians Miss After Concussion | Dr. Julia Treleaven Part I 

Interview with Sameer Jauhar, PhD, author of Incidence and Nature of Antidepressant Discontinuation Symptoms: A Systematic Review and Meta-Analysis. Hosted by John Torous, MD. Related Content: Incidence and Nature of Antidepressant Discontinuation Symptoms

Interview with Sameer Jauhar, PhD, author of Incidence and Nature of Antidepressant Discontinuation Symptoms: A Systematic Review and Meta-Analysis. Hosted by John Torous, MD. Related Content: Incidence and Nature of Antidepressant Discontinuation Symptoms

En lo último en salud y fitness edición de junio 2025, damos un paseo por las últimas tendencias, investigaciones y noticias en el mundo de la salud y el fitness.En este episodio de junio 2025, vamos a explorar varios temas que han estado dando de qué hablar. Hablaremos sobre algo que muchos se preguntan: ¿realmente sirven los baños fríos o calientes después de entrenar? También veremos cómo el entrenamiento de fuerza y el yoga están mostrando resultados prometedores para combatir el cansancio relacionado con el cáncer.Para los padres que nos escuchan, tenemos datos importantes sobre el impacto real de las pantallas en niños pequeños. Y para quienes están pendientes de su alimentación, analizaremos si realmente importa comer 3 o 6 veces al día, además de comparar estrategias de ayuno intermitente para bajar de peso.02:20 - Baños fríos o calientes post-ejercicio: La ciencia dice que da igual 105:03 - Entrenamiento de fuerza y yoga para mejorar el cansancio por cáncer207:25 - El verdadero costo del tiempo frente a la pantalla en preescolares310:28 - ¿Comer 3 o 6 veces al día? Spoiler: ni tu hambre ni tu cuerpo parecen notarlo mucho413:25 - ¿El ayuno intermitente 4:3 es la mejor forma de ayunar para perder peso?5Referencias:1.      Wellauer, V., Clijsen, R., Bianchi, G. & Riggi…, E. No acceleration of recovery from exercise-induced muscle damage after cold or hot water immersion in women: A randomised controlled trial. PloS one (2025).2.      Zhou, S., Chen, G., Xu, X., Zhang, C. & Chen…, G. Comparative Efficacy of Various Exercise Types on Cancer‐Related Fatigue for Cancer Survivors: A Systematic Review and Network Meta‐Analysis of Randomized …. Cancer … (2025).3.      Ahmer, A., Raza, M., Azhar, M., Rahman, A. & Das…, J. K. A Systematic Review and Meta-Analysis on the Impact of Screen-Time on the Social-Emotional Development of Children Under Five Years. Journal of the College of … (2025).4.      Zhang, X., Perrigue, M., Schenk, J. M. & Drewnowski…, A. Objective and subjective appetite measures: high versus low eating frequency in a randomized crossover clinical trial. … (2025).5.      Catenacci, V. A., Ostendorf, D. M. & Pan…, Z. The effect of 4: 3 intermittent fasting on weight loss at 12 months: A randomized clinical trial. Annals of Internal … (2025).

Drug-Coated Balloons Vs Drug-Eluting Stents For The Treatment Of Large Native Coronary Artery Disease: A Meta-Analysis Of Randomized Controlled Trials.

“I grew up with puppetry and voices and weird little characters. I never really let that go — I just found ways to turn it into a life.” - Nate Begle In this episode, we're joined by Nate - He's a voice actor and puppeteer with over two decades of experience in storytelling across stage, screen, and sound. His career has spanned live theme park shows, national commercials, animation, and narration work for over 30 audiobooks. Nate has collaborated with major creative institutions, including James Patterson, The Jim Henson Company, Walt Disney Entertainment, and Sesame Street. Deeply rooted in performance, character work, and voice, Nate brings a grounded and authentic presence to everything he creates. He allows the characters, not the performer, to take center stage.Nate and I nestle in for a tender, playful, and witty conversation about a life built around performance. We talk discovering creative purpose early, navigating years of invisible work, and learning how to keep showing up for the craft even when no one is watching.We talk about his roots in Midwest community theater, how Fraggle Rock cracked open a lifelong fascination with puppetry, and the reality of building a career from bits and odd jobs to full-time creative expression. Along the way, we dive into themes like staying grounded while performing, the therapeutic power of play, self-belief in the face of doubt, and the surprising joy of working just off-camera.From humor and nostalgia to identity and intention, this conversation brings small insights that build into something honest, warm, and very real.More notable quotes from the episode:- “A lot of people think voiceover is just ‘talking,' but it's not. It's acting. It's truth-telling. It's intention.”- “It's like, if you see something that's not available where you're at - then make it.”- “There's a moment where you stop trying to get it perfect and start asking if it feels true. That's when you know you're doing the work.”For more on Nate Begle, head over to his IMDB here: https://www.imdb.com/name/nm4662429/Checkout Nates website here: https://www.natebegle.com/Youtube: https://www.youtube.com/@NateBegleLinkedIn: https://www.linkedin.com/in/nate-begle-785155bb/Hit subscribe, we'll see ya next episode.

Send us a textAll-cause mortality and infection-related outcomes of hospital-initiated kangaroo care versus conventional neonatal care for low-birthweight infants: a systematic review and meta-analysis.Minotti C, Jost K, Aghlmandi S, Schlaeppi C, Sieswerda E, van Werkhoven CH, Schulzke SM, Bielicki JA.Lancet Child Adolesc Health. 2025 Jul;9(7):470-483. doi: 10.1016/S2352-4642(25)00130-0. Epub 2025 May 26.PMID: 40441171 Free article.As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

OVERVIEWHeat acclimation is a big topic this summer, especially because heat training has been shown to also improve oxygen-carrying capacity in the blood - similar to altitude training! But, heat training can be tricky, especially for Time-Crunched Cyclists. What if you can't train in the hottest part of the day because of work? What if you spend your workday in a cold, air conditioned office building? Should you sit passively in a sauna or hot bath, or exercise with extra layers and no fans? For how long, at what temperatures, etc.? Coach Adam Pulford provides actionable, pragmatic heat training guidance for amateur and everyday cyclists so you can perform better in the heat and reduce your risks for heat illness.TOPICS COVEREDWhy should you get heat adaptedHow long does heat adaptation take?Native heat vs. Added HeatTraining Schedule for Native Heat TrainingAir conditioning and "global heat stress"Training Schedule for Added Heat TrainingHow do you know you're heat adapted?LINKS/RESOURCESHeat Adaptation for Females: A Systematic Review and Meta-Analysis of Physiological Adaptations and Exercise Performance in the Heat - PMCGoing one step further with altitude training or heat training Heat training 101: A comprehensive guide for athletesHow much do you sweat? - Asker's Sweat Rate CalculatorHeat training guide for cyclists | EF Pro Cycling https://pmc.ncbi.nlm.nih.gov/articles/PMC6422510/ASK A QUESTION FOR A FUTURE PODCASTHOSTAdam Pulford has been a CTS Coach for nearly two decades and holds a B.S. in Exercise Physiology. He's participated in and coached hundreds of athletes for endurance events all around the world.Listen to the episode on Apple Podcasts, Spotify, Stitcher, Google Podcasts, or on your favorite podcast platformGET FREE TRAINING CONTENTJoin our weekly newsletterCONNECT WITH CTSWebsite: trainright.comInstagram: @cts_trainrightTwitter: @trainrightFacebook: @CTSAthlete

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Sex Differences in the Impact of Exercise Volume on Subclinical Coronary Atherosclerosis: A Meta-Analysis.

Contributor: Taylor Lynch, MD Educational Pearls: How do we risk-stratify chest-pain patients? One option is the HEART score This score predicts a patient's 6-week risk of a major adverse cardiac event. Ex. Cath procedure, CABG, PCI, death H stands for History Ask 1) Was the patient diaphoretic? 2) Did they have nausea and/or vomiting? 3) Did the pain radiate down the right or left arm? 4) Was it exertional? Yes to one = one point. Two or more = two points. E stands for EKG One point for left ventricular hypertrophy, t-wave inversions, new bundle-branch blocks. No points for first degree AV block, benign early repolarization, or QT-prolongation Two points for ST-depression A stands for Age >65 gets two points 45-64 gets one point R stands for Risk factors Hypertension, hyperlipidemia, diabetes, obesity, family history, smoking, previous MI, previous CABG, stroke, peripheral arterial disease 1-2 risk factors get 1 point More than two risk factors gets two points T stands for Troponin 1-3x upper limit of normal gets one point >3x upper limit of normal gets two points This gives you a score between zero and ten 0-3 points, patients have a ~2% chance of an adverse event These patients likely go home 4-6 points, patients have a ~20% chance of an adverse event These patients get admitted or expedited outpatient stress test/echo 7-10 points, patients have a ~60% chance of an adverse event Admit and call cardiology. These patients likely get catheterized References Backus BE, Six AJ, Kelder JC, Bosschaert MA, Mast EG, Mosterd A, Veldkamp RF, Wardeh AJ, Tio R, Braam R, Monnink SH, van Tooren R, Mast TP, van den Akker F, Cramer MJ, Poldervaart JM, Hoes AW, Doevendans PA. A prospective validation of the HEART score for chest pain patients at the emergency department. Int J Cardiol. 2013 Oct 3;168(3):2153-8. doi: 10.1016/j.ijcard.2013.01.255. Epub 2013 Mar 7. PMID: 23465250. Laureano-Phillips J, Robinson RD, Aryal S, Blair S, Wilson D, Boyd K, Schrader CD, Zenarosa NR, Wang H. HEART Score Risk Stratification of Low-Risk Chest Pain Patients in the Emergency Department: A Systematic Review and Meta-Analysis. Ann Emerg Med. 2019 Aug;74(2):187-203. doi: 10.1016/j.annemergmed.2018.12.010. Epub 2019 Feb 2. PMID: 30718010. https://www.mdcalc.com/calc/1752/heart-score-major-cardiac-events Summarized by Jeffrey Olson, MS4 | Edited by Jorge Chalit, OMS4 Donate: https://emergencymedicalminute.org/donate/

In this episode of Quah (Q & A), Sal, Adam & Justin coach three Pump Heads via Zoom. Mind Pump Fit Tip: 3 food additives that are killing your health. (2:13) Plugged vs unplugged. (26:10) Sal's talk at the Peptide World Congress. (36:07) The effects of Acetaldehyde on the gut. (38:40) How family members can hinder one's recovery. (41:38) Two words to define each decade of life. (47:13) Mind Pump is looking for trainers. Apply today! (1:00:21) #ListenerLive question #1 – Is there anyone here with experience, either having been injured or having helped people recover from this type of ongoing trauma? (1:01:36) #ListenerLive question #2 – What program would you guys recommend for teenagers? (1:12:23) #ListenerLive question #3 – Am I correct to allow my core to be such a limiting factor when doing squats, or is my fear the real culprit? (1:27:38) Related Links/Products Mentioned Ask a question to Mind Pump, live! Email: live@mindpumpmedia.com Visit Pre-Alcohol by ZBiotics for an exclusive offer for Mind Pump listeners! ** Promo code MINDPUMP25 for 15% off first-time purchasers on either one-time purchases, (3, 6, 12-packs) or subscriptions (6, 12-pack) ** Visit Rock Recovery Center for the exclusive offer for Mind Pump listeners! ** Ben and Tom know firsthand the struggles of addiction and alcoholism. With years of experience helping thousands of individuals, they offer a free consultation call to discuss your situation. Whether you're personally battling addiction or have a loved one in need of help, they're here to guide you toward the support you need. By filling out the form and scheduling your call, you'll also be entered for a chance to win a free 60-day scholarship at Rock Recovery Center, their premier treatment center in West Palm Beach, Florida. Don't wait—take the first step today. ** Special MAPS Longevity Launch: ** Code 50LONG for $50 off, now $97 (regularly $147). Bonuses: Forum access for a year ($97), Post-Launch Kickoff Zoom call ($97). Expires on 6/22 (30-day money-back guarantee). **June Special: Shredded Summer Bundle or Bikini Bundle 50% off! ** Code JUNE50 at checkout ** Scientist's Study Led FDA to Ban Red No. 3 Food Dye. Yet He Says It Is Safe Distinct Gut Microbiota Signatures in Mice Treated with Commonly Used Food Preservatives Processed meat and colorectal cancer: a review of epidemiologic and experimental evidence Ultra-Processed Food Consumption and Mental Health: A Systematic Review and Meta-Analysis of Observational Studies Mind Pump Personal Training – Apply today! Get your free Sample Pack with any “drink mix” purchase! Also, try the new LMNT Sparkling — a bold, 16-ounce can of sparkling electrolyte water: Visit DrinkLMNT.com/MindPump MAPS Prime Pro Webinar The Dunphy Squat | At Home Squat Variation – YouTube Mind Pump Podcast – YouTube Mind Pump Free Resources People Mentioned Michael Israetel (@drmikeisraetel) Instagram Thomas Conrad (@realrecoverytalktom) Instagram Ben Bueno (@realrecoverytalkben) Instagram  

This episode discusses findings from a recent systematic review preprint, examining how the embryonic germ layer origin of various cancers may relate to differences in therapy response. Drawing on evidence from clinical trials and mechanistic studies, we explore patterns observed among mesoderm-, endoderm-, and ectoderm-derived tumors.The conversation highlights how integrating developmental biology concepts into oncology may help inform treatment decisions and research design. This episode is intended for students, researchers, and clinicians interested in cancer biology, translational research, and personalized medicine.Please note: The views of this podcast represent those of my guest and I, and do not constitute medical advice, recommendations or consultations. Please see a state certified and board certified professional for medical, advice and recommendations. We disclaim any loss in any way.Link to Preprint: Embryonic Germ Layer Origin as a Potential Determinant of Cancer Therapy Response: A Systematic Review and Meta-Analysis of Contemporary Evidence | medRxivNote: Some of this episode's production involved the use of AI.

Once the most popular graft choice for ACL reconstruction surgery, hamstring autograft has recently fallen out of favor for a variety of concerns including a higher graft rupture rate in younger athletes and concerns over graft diameters that tend to run smaller. However, what does the best level evidence actually say about hamstring autograft's long-term performance versus the current gold-standard, patellar tendon autograft? Dr. Derrick Knapick, MD joins us from Washington University School of Medicine in St. Louis to discuss his study looking at this question.    

Train the Best. Change EMS.Howdy, y'all, I'm Dr Jeff Jarvis, and I'm the host of the EMS lighthouse project podcast, but I'm also the medical director for the new EMS system we're building in Fort Worth Texas. We are looking for an experienced critical care paramedic who is an effective and inspiring educator to lead the initial and continuing training and credentialing of a new team of Critical Care Paramedics who will be responding to our highest acuity calls. The salary is negotiable but starts between $65,000 and $80,000 a year for this office position. Whether y'all wear cowboy boots or Birkenstocks, Fort Worth can be a great place to live and work. So if you're ready to create a world-class EMS system and change the EMS world with us, give us a call at 817-953-3083, take care y'all.The next time you go to intubate a patient, should you give the sedation before the paralytic or the paralytic before the sedative? Does it matter? And what the hell does Bayes have to do with any of this? Dr Jarvis reviews a paper that uses Bayesian statistics to calculate the association between drug sequence and first attempt failure. Then he returns to Nerd Valley to talk about how to interpret 95% confidence intervals derived from frequentists statistics compared to 95% credible intervals that come from Bayesian statistics. Citations:1.     Catoire P, Driver B, Prekker ME, Freund Y: Effect of administration sequence of induction agents on first‐attempt failure during emergency intubation: A Bayesian analysis of a prospective cohort. Academic Emergency Medicine. 2025;February;32(2):123–9. 2.     Casey JD, Janz DR, Russell DW, Vonderhaar DJ, Joffe AM, Dischert KM, Brown RM, Zouk AN, Gulati S, Heideman BE, et al.: Bag-Mask Ventilation during Tracheal Intubation of Critically Ill Adults. N Engl J Med. 2019;February 28;380(9):811–21.3.     Greer A, Hewitt M, Khazaneh PT, Ergan B, Burry L, Semler MW, Rochwerg B, Sharif S: Ketamine Versus Etomidate for Rapid Sequence Intubation: A Systematic Review and Meta-Analysis of Randomized Trials. Critical Care Medicine. 2025;February;53(2):e374–83.

Dr. Aditi Nerurkar discusses the neuroscience behind stress—and offers actionable tips for building your resilience.— YOU'LL LEARN — 1) The major myth that leads to burnout 2) The rule of two for building healthier habits 3) How to feel less stressed in one minuteSubscribe or visit AwesomeAtYourJob.com/ep1065 for clickable versions of the links below. — ABOUT ADITI — Dr. Aditi Nerurkar is a Harvard stress expert, internationally recognized speaker, and national television correspondent with an expertise in stress, burnout, resilience and mental health. Her book The 5 Resets: Rewire Your Brain and Body for Less Stress and More Resilience is a “must read” by Adam Grant and Malcolm Gladwell's Next Big Idea Club and “best new book” by the New York Post. Named “100 Women to Know in America,” her work has been featured in The New York Times, The Washington Post, Good Morning America, The Today Show and NPR. She is also a frequent keynote speaker with talks at the Forbes 30 Under 30 Summit and other events.• Book: The 5 Resets: Rewire Your Brain and Body for Less Stress and More Resilience • Test: Your Stress Score • Website: DrAditi.com— RESOURCES MENTIONED IN THE SHOW — • Tool: Holmes and Rahe stress scale • Study: “Association of wearable device-measured vigorous intermittent lifestyle physical activity with mortality” by Emmanuel Stamatakis, et al. • Study: “Effects of Exercise on Patients with Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis” by Jiale Peng, Yuling Yuan, Yuanhui Zhao, and Hong Ren • Past episode: 996: Tackling Work Stressors and Transitions with Dr. Tessa West — THANK YOU SPONSORS! — • Strawberry.me. Claim your $50 credit and build momentum in your career with Strawberry.me/Awesome• Quince. Get free shipping and 365-day returns on your order with Quince.com/AwesomeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode, I sat down with Dr. Suzette Sutherland, a seasoned urologist who recently transitioned from the University of Washington to a large urology group in Arizona. Dr. Sutherland shares her expertise on treating overactive bladder (OAB) and the latest innovation in neuromodulation therapies, specifically focusing on the efficacy and safety of tibial nerve stimulation. We discuss the evolution of treatment guidelines, the pros and cons of various therapies, including medications, Botox, and sacral nerve stimulation, and dive deep into the promising results from the FDA-approved Revi device from BlueWind. Dr. Sutherland also sheds light on patient selection, procedural details, and patient compliance, while offering insights into the future of OAB treatments.For information on the REVI   https://bluewindmedical.com/Timeline:00:30 Introduction and Guest Introduction01:10 Understanding Overactive Bladder and Treatment Options02:19 Tibial Nerve Stimulation: A New Approach02:40 Changes in Treatment Guidelines05:57 Mechanism of Tibial Nerve Stimulation09:38 Implantable Tibial Nerve Stimulation Devices13:39 Patient Experience and Compliance17:54 Comparing Neuromodulation Devices25:37 Comparing Revi and Eco Devices26:32 Understanding Device Placement and Stimulation Frequency27:18 Battery Life and Replacement Concerns29:33 New Devices on the Horizon30:03 Meta-Analysis of Tibial Nerve Stimulation32:49 Patient Choices: Sacral Nerve Stimulation vs. Tibial Nerve Stimulation38:22 The Role of Botox in Bladder Treatment46:14 Challenges and Innovations in Urogynecology

Send us a textActive Treatment vs Expectant Management of Patent Ductus Arteriosus in Preterm Infants: A Meta-Analysis.Buvaneswarran S, Wong YL, Liang S, Quek SC, Lee J.JAMA Pediatr. 2025 May 27:e251025. doi: 10.1001/jamapediatrics.2025.1025. Online ahead of print.PMID: 40423988 Free PMC As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

In this episode of the Movement Logic Podcast, Sarah explores the commonly held belief that any amount of exercise is better than none. Using recent research, she discusses the benefits of minimal exercise on cardiovascular health and longevity but also highlights the limitations of this advice. She emphasizes the need for strength training and power exercises to meet the comprehensive physical needs of the body, especially as we age. Additionally, she discusses the socioeconomic barriers to regular exercise and suggests systemic changes to make meaningful physical activity more accessible to everyone.Sign up for the Wait List for our Bone Density Course!00:03 The Common Exercise Advice: Just Do Something02:01 Scientific Evidence Supporting Minimal Exercise06:58 Limitations of Minimal Exercise10:01 Strength Training and Its Importance16:35 Challenges and Practical Solutions for Exercise22:12 Conclusion and Final ThoughtsReferences:Dose-response associations between accelerometry measured physical activity and sedentary time and all cause mortality: systematic review and harmonised meta-analysisPhysical Activity, All-Cause and Cardiovascular Mortality, and Cardiovascular DiseaseAssociation of wearable device-measured vigorous intermittent lifestyle physical activity with mortalityResistance Training and Mortality Risk: A Systematic Review and Meta-AnalysisEffects of Resistance Training Frequency on Measures of Muscle Hypertrophy: A Systematic Review and Meta-Analysis

Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association's four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 25 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians and health care professionals, Diabetes Core Update   discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting. Welcome to diabetes core update where every month we go over the most important articles to come out in the field of diabetes. Articles that are important for practicing clinicians to understand to stay up with the rapid changes in the field.  This issue will review: 1.    Intensive Blood-Pressure Control in Patients with Type 2 Diabetes 2.    Cardioprotective Glucose-Lowering Agents and Dementia Risk A Systematic Review and Meta-Analysis 3.    A Randomized Trial of Automated Insulin Delivery in Type 2 Diabetes 4.    Screening for Metabolic Dysfunction–Associated Steatotic Liver Disease–Related Advanced Fibrosis 5.    Risk of Urogenital Infections in People With Type 2 Diabetes Initiating SGLT2i Versus GLP-1RA in Routine Clinical Care   For more information about each of ADA's science and medical journals, please visit Diabetesjournals.org. Hosts: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Chair-Department of Family Medicine, Abington Jefferson Health

If you've heard anything about the study of human personality, you've probably heard about the “big five.” This is a framework that attempts to characterize human personality in terms of five broad factors or dimensions—neuroticism, extraversion, openness, conscientiousness, and agreeableness. The big five framework has been enormously influential, generating heaps and heaps of data, and study after study on the stability of personality, on the factors that shape our personalities, on how our personalities predict success and satisfaction. But is the big five really the best we can do? What does it miss? What does it mask? Where should the science of human personality go next? My guest today is Dr. René Mõttus. René is Professor of Psychology at the University of Edinburgh, and a leading researcher in the scientific study of human personality. He's also one of the hosts of the Personality Psychology Podcast. Here, René and I talk about the history and colossal success of the “big five.” We consider whether personality is ultimately rooted in our biology—and, if so, how. We dwell on each of the five factors and dig into the facets and nuances within them. These are, actually, technical terms in the field for the more granular aspects of personality that sit within each of these broad dimensions. We talk about personality change across the lifespan, and what factors seem to be driving it. We talk about personality and occupation, personality and birth order, personality and gender. Along the way, René and I touch on the Myers-Briggs; an alternative to the Big 5 known as the HEXACO model; the power of explicit questionnaires over experiments; the concept of "personality age"; the social investment theory; honesty, humility, humor, jealousy; life satisfaction; gene-environment correlations; and why evolutionary stories about personality seem to fail. Alright friends, I think you'll like this one. On to my conversation with Dr. René Mõttus. Enjoy!   A transcript of this episode will be posted soon.   Notes and links 5:30 – For a popular discussion of the Myers-Briggs and other personality tests, see here. For a book-length treatment of the history of the Myers-Briggs test, see here. 11:30 – For Dr. Mõttus's preprint on “personality age,” see here. 17:00 – For our episode on animal personality with Dr. Kate Laskowski, see here. 18:00 – For Dr. Daniel Nettle's book on personality, see here. 22:00 – See Dr. Mõttus's blog post on the genetic basis of personality. 25:00 – For our episode with Dr. Eric Turkheimer about IQ, see here. For Dr. Turkheimer's “phenotypic null hypothesis” about personality, see here. 28:00 – For a theoretical paper by Dr. Mõttus and colleagues about “carving personality at its joints” and “big few models”—among many other issues—see here. 31:00 – See here for a classic overview of the “big five.” 38:00 – For an overview of the predictive power of the “big five,” see here. 40:00 – On the topic of “nuances,” see Dr. Mõttus's recent co-authored paper here. 43:00 – For the study by Dr. Mõttus and colleagues of the personality profiles of different occupations, see here. For an online tool that allows you to explore the data, see here. For an online tool that matches your personality with the personality profiles of different occupations, see here. 47:00 – A classic paper on the HEXACO model of personality. 51:00 – An example of a recent effort to map out the “facets” of personality. 1:11:00 – For a study on the possibility of gene-environment correlations in the area of music, see here. For the study by Dr. Mõttus and colleagues on children “becoming less alike” through adolescence, see here. 1:18:00 – For a classic statement of the “five factor theory,” see here. 1:20:00 – The Wikipedia page for the idea of the “gloomy prospect” is here. This is also the name of Dr. Turkheimer's newsletter. 1:22:00 – The latest installment in the longstanding debate about birth order and personality. 1:27:00 – A paper comparing the “five factor” and “social investment” accounts of personality development. 1:33:00 – For a recent paper by Dr. Mõttus and colleagues on personality and gender, see here. 1:38:00 – A research article on the Estonian Biobank.   Recommendations ‘Life Events and Personality Change: A Systematic Review and Meta-Analysis,' by Bühler et al. ‘Personality stability and change: A meta-analysis of longitudinal studies,' by Bleidorn et al. ‘Choosing prediction over explanation in psychology: Lessons from machine learning,' by Yarkoni & Westfall   Many Minds is a project of the Diverse Intelligences Summer Institute, which is made possible by a generous grant from the John Templeton Foundation to Indiana University. The show is hosted and produced by Kensy Cooperrider, with help from Assistant Producer Urte Laukaityte and with creative support from DISI Directors Erica Cartmill and Jacob Foster. Our artwork is by Ben Oldroyd. Our transcripts are created by Sarah Dopierala. Subscribe to Many Minds on Apple, Stitcher, Spotify, Pocket Casts, Google Play, or wherever you listen to podcasts. You can also now subscribe to the Many Minds newsletter here! We welcome your comments, questions, and suggestions. Feel free to email us at: manymindspodcast@gmail.com.  For updates about the show, visit our website or follow us on Twitter (@ManyMindsPod) or Bluesky (@manymindspod.bsky.social).

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Prevalence, Risk Factors, and Prognosis for Fontan-Associated Liver Disease: A Systematic Review and Exploratory Meta-Analysis.

  In this Q&A episode, Dr. Rebecca Dekker answers questions submitted by EBB Pro Members—each exploring a different facet of evidence-based maternity care.   First, she explores the latest evidence on early induction for gestational hypertension, including findings from the WILL trial and other recent studies. What are the real risks and benefits of inducing labor at 37 or 38 weeks for gestational hypertension? And how should families weigh these decisions with their providers?   Next, Dr. Dekker shares new insights into the effectiveness of acupuncture and acupressure for labor pain, anxiety, and Cesarean recovery. From systematic reviews to randomized trials, the data is growing!   Finally, she looks into the evidence on interpregnancy intervals. What does the research say about the risks associated with short or long gaps between pregnancies? And how might this information apply to those who are pregnant again after a five-year or more break?   (00:00) Intro to Mini Q&A and EBB Pro Membership (02:17) Early Induction for Gestational Hypertension – What the Research Says (06:20) WILL Trial Findings and Recommendations from ACOG and NICE (08:23) Outcomes at 37 vs. 38 Weeks – Cesareans, NICU, and Respiratory Distress (10:15) Balancing Induction Timing and Risks of Continuing Pregnancy (11:03) Acupuncture and Acupressure – New Research and Applications (12:41) Studies on Pain, Anxiety, and Nausea During Labor and Cesareans (14:46) Acupuncture and Cesarean Recovery – Mobility and Pain Management (16:54) Interpregnancy Intervals – Definitions and Research Challenges (19:39) Risks of Short and Long Pregnancy Spacing (23:22) Global Perspectives and Meta-Analysis on Birth Outcomes (26:49) Public Health Implications and Final Thoughts   View the full list of resources and references on ebbirth.com.   For more information about Evidence Based Birth® and a crash course on evidence based care, visit www.ebbirth.com. Follow us on Instagram and YouTube! Ready to learn more? Grab an EBB Podcast Listening Guide or read Dr. Dekker's book, "Babies Are Not Pizzas: They're Born, Not Delivered!" If you want to get involved at EBB, join our Professional membership (scholarship options available) and get on the wait list for our EBB Instructor program. Find an EBB Instructor here, and click here to learn more about the EBB Childbirth Class.

Send us a textThis recording features audio versions of June 2025 Journal of Vascular and Interventional Radiology (JVIR) abstracts:Comparison of Bypass Surgery versus Endovascular Interventions for Peripheral Artery Disease through Systematic Review and Meta-Analysis of Randomized Controlled Trials ReadThe Incidence and Consequences of Endovascular Technical Failure in Patients with Chronic Limb-Threatening Ischemia: Results from the Best Endovascular versus Best Surgical Therapy in Patients with Critical Limb-Threatening Ischemia (BEST-CLI) Trial ReadComparative Radiologic Response Assessment after Transarterial Chemoembolization, Percutaneous Ablation, and Multimodal Treatment: Radiologic-Pathologic Correlation in 81 Tumors ReadBreast Cancer Recurrence after Cryoablation in Patients Who Are Poor Surgical Candidates or Who Refuse Surgery ReadKetamine/Midazolam versus Fentanyl/Midazolam Sedation for Interventional Radiology Procedures: A Prospective Registry ReadPortal and Hepatic Vein Embolization versus Portal Venous Embolization Alone in Cirrhotic and Noncirrhotic Swine: A Pilot Study ReadAssessment of Catheter-Directed Thrombolysis and Histotripsy Treatment for Deep Vein Thrombosis ReadExpanding Global IR Outreach to Address Postpartum Hemorrhage in Kenya Using Geospatial Analytic Mapping ReadJVIR and SIR thank all those who helped record this episode. To sign up to help with future episodes, please contact our outreach coordinator at millennie.chen.jvir@gmail.com.  Host and audio Editor:Sonya Choe, University of California Riverside School of MedicineOutreach coordinator:Millennie Chen, University of California Riverside School of MedicineAbstract readers:Marc Attalla, University of California Riverside School of MedicineAgnes Manish, Loma Linda University School of MedicineClare Necas, Western University of Health Sciences, College of Osteopathic MedicineGavin Shu, University of California San Francisco School of MedicineMark Oliinik, Loma Linda University School of MedicineAbhisri Ramesh, George Washington School of Medicine and Health SciencesAndrew Sasser, University of Miami Miller School of Medicine Sakeena Siddiq, Western University of Health Sciences, College of Osteopathic MedicineSIR thanks BD for its generous support of the Kinked Wire.Read more about about interventional radiology in IR Quarterly magazine or SIR's Patient Center.Support the show

Join JACC Editor in Chief Harlan Krumholz, MD, SM, as he speaks about this ACC.25 presentation published in JACC. This fascinating study by Rohan Khera et al independently analyzed patient-level data from the SURMOUNT trials of tirzepatide for obesity. The study revealed striking individual variability in weight loss and metabolic response, even to a highly effective therapy—an insight powerfully illustrated through waterfall plots. Reviewers praised the transparent, sponsor-independent approach and the study's contribution to precision medicine, though they noted it was descriptive rather than predictive, underscoring the need for future research to identify what drives differential treatment response.

Send us a textPrenatal Cannabis Use and Neonatal Outcomes: A Systematic Review and Meta-Analysis.Lo JO, Ayers CK, Yeddala S, Shaw B, Robalino S, Ward R, Kansagara D.JAMA Pediatr. 2025 May 5:e250689. doi: 10.1001/jamapediatrics.2025.0689. Online ahead of print.PMID: 40323610As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Title: Journal Club Series Episode 13-  Systematic review and meta-analysis Target Audience This activity is directed to physicians, medical students, nurse practitioners, nurses, and physician assistants. Objectives: Upon completion of this activity, participants should be able to: •      Conduct systematic reviews and apply proper methodologies. •      Perform meta-analyses and utilize appropriate techniques.  Course Directors: Tony R. Tarchichi MD — Associate Professor, Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center (UPMC.) Paul C. Gaffney Division of Pediatric Hospital Medicine. No relationships with industry relevant to the content of this educational activity have been disclosed. Mary Lou Klem PhD, MLIS — Assistant Director for Advanced Information Support, University of Pittsburgh School of Medicine, Health Sciences Library System No relationships with industry relevant to the content of this educational activity have been disclosed. Conflict of Interest Disclosure: No other planners, members of the planning committee, speakers, presenters, authors, content reviewers and/or anyone else in a position to control the content of this education activity have relevant financial relationships to disclose. Accreditation Statement: In support of improving patient care, the University of Pittsburgh is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.  The University of Pittsburgh School of Medicine designates this enduring material activity for a maximum of 0.75 AMA PRA Category 1 CreditsTM. Physicians should only claim credit commensurate with the extent of their participation in the activity. Other health care professionals will receive a certificate of attendance confirming the number of contact hours commensurate with the extent of participation in this activity. Disclaimer Statement: The information presented at this activity represents the views and opinions of the individual presenters, and does not constitute the opinion or endorsement of, or promotion by, the UPMC Center for Continuing Education in the Health Sciences, UPMC / University of Pittsburgh Medical Center or Affiliates and University of Pittsburgh School of Medicine.  Reasonable efforts have been taken intending for educational subject matter to be presented in a balanced, unbiased fashion and in compliance with regulatory requirements. However, each program attendee must always use his/her own personal and professional judgment when considering further application of this information, particularly as it may relate to patient diagnostic or treatment decisions including, without limitation, FDA-approved uses and any off-label uses. Released 4/15/2025,  Expires 4/15/2028 The direct link to the course is provided below: https://cme.hs.pitt.edu/ISER/app/learner/loadModule?moduleId=25796&dev=true  

Our last poster is titled Outcomes and Return to Sport Following Arthroscopic Bankart Repair for Anterior Shoulder Instability in Contact versus Non-contact Athletes: A Systematic Review and Meta-Analysis.  We've spoken a lot about the surgical treatment for anterior shoulder instability on this podcast – most recently with Dr. Brian Lau.  That is episode #48 and 49 if you want to check it out.This study focused on outcomes of arthroscopic Bankart repair for the treatment of anterior shoulder instability, specifically comparing outcomes in contact athletes versus noncontact athletes.  This systematic review included 18 studies with 1-year minimum follow-up.The authors found that contact and noncontact athletes had similar rates of return to sport as well as similar rates of return to preinjury level of play.  However, they also found that contact athletes demonstrated significantly greater rates of recurrent instability, at 28% compared to 8% in noncontact athletes.  Contact athletes also demonstrated significantly greater need for revision surgery, at 12% compared to 3% in noncontact athletes.

Send us a textCord Blood Treatment for Children With Cerebral Palsy: Individual Participant Data Meta-Analysis.Finch-Edmondson M, Paton MCB, Webb A, Reza Ashrafi M, Blatch-Williams RK, Cox CS Jr, Crompton K, Griffin AR, Kim M, Kosmach S, Kurtzberg J, Nouri M, Ri Suh M, Sun J, Zarrabi M, Novak I.Pediatrics. 2025 Apr 11:e2024068999. doi: 10.1542/peds.2024-068999. Online ahead of print.PMID: 40210215As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Spring is the perfect time to shake up your routine. In this episode, Professor Tim Spector and Dr. Federica Amati reveal seven delicious, science-backed foods that help cool the flame of chronic inflammation. Whether you're dealing with bloating, aching joints, or low energy, this episode is packed with easy, gut-friendly tips to help you feel your best this season. Tim and Federica begin by explaining what inflammation really is and when it becomes a problem. Then, they'll introduce seven anti-inflammatory foods that are as powerful as they are delicious. From cruciferous vegetables to fermented surprises, these everyday ingredients can help you build a more resilient, healing diet.  Finally, they offer a roadmap for long-term change. Tim and Fed each share one small but powerful shift to reduce inflammation over four timelines - what you can do today, this week, this month, and throughout the year - to create habits that truly stick.

In this episode of Iron Culture, host Eric Trexler and guest Jake Remmert discuss a new meta regression paper focusing on per session set volume and its impact on hypertrophy and strength. They explore the nuances of per session training volume, the implications of the findings, and address common misconceptions in the fitness community. The conversation emphasizes the importance of understanding the data and its limitations while providing practical applications for training. Time Stamps: 00:00 Introduction 00:30 Jake Remmert's Background and Journey 06:18 Transition to Research and Meta-Analysis 16:24 Exploring Per Session Set Volume 23:27 Methodological Approach to the Study 26:22 Results and Practical Applications 27:33 Defining Terminology and Effect Sizes 30:10 Exploring Hypertrophy and Set Volume Relationships 33:54 Practical Recommendations for Training Volume 37:43 Understanding Variance in Data and Its Implications 46:50 Transitioning to Strength Results and Their Insights 58:55 Practical Applications and Training Adjustments 01:03:26 Volume and Recovery: Finding the Balance 01:07:08 The Importance of Frequency in Training 01:10:00 Understanding Volume and Its Impact on Performance 01:12:32 Interpreting Research: The Nuances of Meta-Analysis 01:24:43 Final Thoughts

In this episode of Iron Culture, hosts Eric Helms and Eric Trexler engage in a lively discussion with Dr. James Steele about the evolving landscape of sports science, particularly focusing on the critiques of periodization and the importance of scientific theory in exercise research. They explore the philosophical underpinnings of scientific inquiry, the challenges of conducting robust research, and the implications of recent studies on training effects. The conversation emphasizes the need for a more theory-driven approach in exercise science to enhance the validity and applicability of research findings. In this conversation, James Steele and Eric Helms discuss the intricacies of designing meaningful studies in hypertrophy research, emphasizing the importance of collaboration, causal inference, and the need for high-powered studies. They explore the challenges of resistance training research, the significance of theory corroboration, and the future directions for the field. The discussion highlights the necessity of passion and purpose in research, advocating for a focus on practical applications and the importance of understanding the underlying mechanisms of training effects. Time stamps: 00:00 Introduction 03:55 The Role of Periodization in Sports Science 11:45 Critique of Periodization and Scientific Methodology 24:50 Philosophy of Science in Exercise Science 33:12 Understanding Sports Science Models 35:56 Philosophy of Science in Sports Research 40:00 The Importance of Critical Thinking 44:35 Diving into the Study 48:38 Theory of Adaptation in Resistance Training 54:47 Intervention Effects and Practical Implications 59:10 Meta-Analysis and Evidence in Sports Science 01:19:50 The Value of Individual Studies vs. Meta-Analyses 01:24:03 Understanding Causal Inference in Research 01:27:41 The Importance of Baseline Theory in Training 01:29:28 Identifying Small Effects in Research 01:33:16 The Role of Collaboration in Sports Science 01:38:38 Leveraging Data for Performance Insights 01:41:08 The Distinction Between Sports Science and Exercise Science 01:44:59 Learning from Other Fields: Causal Inference in Sports 01:47:29 Passion and Purpose in Research 01:50:02 Concluding Thoughts on the Future of Research