Podcast appearances and mentions of meta analysis

Heath and Bailey review the balance data slate and the new Wrath of the Rock Detachment.If you want to learn more about Dank Lists Wargaming then follow us on our social medias listed below and subscribe here:Email: danklistswargaming@gmail.comFacebook: https://www.facebook.com/danklists/Instagram: https://www.instagram.com/danklistswargaming/Twitch: https://www.twitch.tv/danklistswargamingTwitter: https://twitter.com/DankListsWebsite: https://danklistswargaming.wixsite.com/danklistsMDF Terrain by Laser Craft Workshop: https://lasercraftworkshop.com/Video made using Da Vinci 20.Credit: "Music: https://www.purple-planet.com'For written Meta Analysis, please visit: https://40kangelskeep.blogspot.com/

Sensorimotor Dysfunction & the Cervical Spine: What Clinicians Miss After Concussion | Dr. Julia Treleaven Part I 

Interview with Sameer Jauhar, PhD, author of Incidence and Nature of Antidepressant Discontinuation Symptoms: A Systematic Review and Meta-Analysis. Hosted by John Torous, MD. Related Content: Incidence and Nature of Antidepressant Discontinuation Symptoms

Interview with Sameer Jauhar, PhD, author of Incidence and Nature of Antidepressant Discontinuation Symptoms: A Systematic Review and Meta-Analysis. Hosted by John Torous, MD. Related Content: Incidence and Nature of Antidepressant Discontinuation Symptoms

En lo último en salud y fitness edición de junio 2025, damos un paseo por las últimas tendencias, investigaciones y noticias en el mundo de la salud y el fitness.En este episodio de junio 2025, vamos a explorar varios temas que han estado dando de qué hablar. Hablaremos sobre algo que muchos se preguntan: ¿realmente sirven los baños fríos o calientes después de entrenar? También veremos cómo el entrenamiento de fuerza y el yoga están mostrando resultados prometedores para combatir el cansancio relacionado con el cáncer.Para los padres que nos escuchan, tenemos datos importantes sobre el impacto real de las pantallas en niños pequeños. Y para quienes están pendientes de su alimentación, analizaremos si realmente importa comer 3 o 6 veces al día, además de comparar estrategias de ayuno intermitente para bajar de peso.02:20 - Baños fríos o calientes post-ejercicio: La ciencia dice que da igual 105:03 - Entrenamiento de fuerza y yoga para mejorar el cansancio por cáncer207:25 - El verdadero costo del tiempo frente a la pantalla en preescolares310:28 - ¿Comer 3 o 6 veces al día? Spoiler: ni tu hambre ni tu cuerpo parecen notarlo mucho413:25 - ¿El ayuno intermitente 4:3 es la mejor forma de ayunar para perder peso?5Referencias:1.      Wellauer, V., Clijsen, R., Bianchi, G. & Riggi…, E. No acceleration of recovery from exercise-induced muscle damage after cold or hot water immersion in women: A randomised controlled trial. PloS one (2025).2.      Zhou, S., Chen, G., Xu, X., Zhang, C. & Chen…, G. Comparative Efficacy of Various Exercise Types on Cancer‐Related Fatigue for Cancer Survivors: A Systematic Review and Network Meta‐Analysis of Randomized …. Cancer … (2025).3.      Ahmer, A., Raza, M., Azhar, M., Rahman, A. & Das…, J. K. A Systematic Review and Meta-Analysis on the Impact of Screen-Time on the Social-Emotional Development of Children Under Five Years. Journal of the College of … (2025).4.      Zhang, X., Perrigue, M., Schenk, J. M. & Drewnowski…, A. Objective and subjective appetite measures: high versus low eating frequency in a randomized crossover clinical trial. … (2025).5.      Catenacci, V. A., Ostendorf, D. M. & Pan…, Z. The effect of 4: 3 intermittent fasting on weight loss at 12 months: A randomized clinical trial. Annals of Internal … (2025).

Drug-Coated Balloons Vs Drug-Eluting Stents For The Treatment Of Large Native Coronary Artery Disease: A Meta-Analysis Of Randomized Controlled Trials.

“I grew up with puppetry and voices and weird little characters. I never really let that go — I just found ways to turn it into a life.” - Nate Begle In this episode, we're joined by Nate - He's a voice actor and puppeteer with over two decades of experience in storytelling across stage, screen, and sound. His career has spanned live theme park shows, national commercials, animation, and narration work for over 30 audiobooks. Nate has collaborated with major creative institutions, including James Patterson, The Jim Henson Company, Walt Disney Entertainment, and Sesame Street. Deeply rooted in performance, character work, and voice, Nate brings a grounded and authentic presence to everything he creates. He allows the characters, not the performer, to take center stage.Nate and I nestle in for a tender, playful, and witty conversation about a life built around performance. We talk discovering creative purpose early, navigating years of invisible work, and learning how to keep showing up for the craft even when no one is watching.We talk about his roots in Midwest community theater, how Fraggle Rock cracked open a lifelong fascination with puppetry, and the reality of building a career from bits and odd jobs to full-time creative expression. Along the way, we dive into themes like staying grounded while performing, the therapeutic power of play, self-belief in the face of doubt, and the surprising joy of working just off-camera.From humor and nostalgia to identity and intention, this conversation brings small insights that build into something honest, warm, and very real.More notable quotes from the episode:- “A lot of people think voiceover is just ‘talking,' but it's not. It's acting. It's truth-telling. It's intention.”- “It's like, if you see something that's not available where you're at - then make it.”- “There's a moment where you stop trying to get it perfect and start asking if it feels true. That's when you know you're doing the work.”For more on Nate Begle, head over to his IMDB here: https://www.imdb.com/name/nm4662429/Checkout Nates website here: https://www.natebegle.com/Youtube: https://www.youtube.com/@NateBegleLinkedIn: https://www.linkedin.com/in/nate-begle-785155bb/Hit subscribe, we'll see ya next episode.

In this podcast, HyunJoon Kim & Claudio Ferre discuss their paper 'Transcranial direct current stimulation and motor function in children with cerebral palsy: A systematic review and meta-analysis'.   The paper is available here: https://doi.org/10.1111/dmcn.16365   Follow DMCN on Podbean for more: https://dmcn.podbean.com/ ___ Watch DMCN Podcasts on YouTube: https://bit.ly/2ONCYiC __ DMCN Journal: Developmental Medicine & Child Neurology (DMCN) has defined the field of paediatric neurology and childhood-onset neurodisability for over 60 years. DMCN disseminates the latest clinical research results globally to enhance the care and improve the lives of disabled children and their families. DMCN Journal - https://onlinelibrary.wiley.com/journal/14698749 ___ Find us on Twitter! @mackeithpress - https://twitter.com/mackeithpress

Send us a textAll-cause mortality and infection-related outcomes of hospital-initiated kangaroo care versus conventional neonatal care for low-birthweight infants: a systematic review and meta-analysis.Minotti C, Jost K, Aghlmandi S, Schlaeppi C, Sieswerda E, van Werkhoven CH, Schulzke SM, Bielicki JA.Lancet Child Adolesc Health. 2025 Jul;9(7):470-483. doi: 10.1016/S2352-4642(25)00130-0. Epub 2025 May 26.PMID: 40441171 Free article.As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

OVERVIEWHeat acclimation is a big topic this summer, especially because heat training has been shown to also improve oxygen-carrying capacity in the blood - similar to altitude training! But, heat training can be tricky, especially for Time-Crunched Cyclists. What if you can't train in the hottest part of the day because of work? What if you spend your workday in a cold, air conditioned office building? Should you sit passively in a sauna or hot bath, or exercise with extra layers and no fans? For how long, at what temperatures, etc.? Coach Adam Pulford provides actionable, pragmatic heat training guidance for amateur and everyday cyclists so you can perform better in the heat and reduce your risks for heat illness.TOPICS COVEREDWhy should you get heat adaptedHow long does heat adaptation take?Native heat vs. Added HeatTraining Schedule for Native Heat TrainingAir conditioning and "global heat stress"Training Schedule for Added Heat TrainingHow do you know you're heat adapted?LINKS/RESOURCESHeat Adaptation for Females: A Systematic Review and Meta-Analysis of Physiological Adaptations and Exercise Performance in the Heat - PMCGoing one step further with altitude training or heat training Heat training 101: A comprehensive guide for athletesHow much do you sweat? - Asker's Sweat Rate CalculatorHeat training guide for cyclists | EF Pro Cycling https://pmc.ncbi.nlm.nih.gov/articles/PMC6422510/ASK A QUESTION FOR A FUTURE PODCASTHOSTAdam Pulford has been a CTS Coach for nearly two decades and holds a B.S. in Exercise Physiology. He's participated in and coached hundreds of athletes for endurance events all around the world.Listen to the episode on Apple Podcasts, Spotify, Stitcher, Google Podcasts, or on your favorite podcast platformGET FREE TRAINING CONTENTJoin our weekly newsletterCONNECT WITH CTSWebsite: trainright.comInstagram: @cts_trainrightTwitter: @trainrightFacebook: @CTSAthlete

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Sex Differences in the Impact of Exercise Volume on Subclinical Coronary Atherosclerosis: A Meta-Analysis.

Contributor: Taylor Lynch, MD Educational Pearls: How do we risk-stratify chest-pain patients? One option is the HEART score This score predicts a patient's 6-week risk of a major adverse cardiac event. Ex. Cath procedure, CABG, PCI, death H stands for History Ask 1) Was the patient diaphoretic? 2) Did they have nausea and/or vomiting? 3) Did the pain radiate down the right or left arm? 4) Was it exertional? Yes to one = one point. Two or more = two points. E stands for EKG One point for left ventricular hypertrophy, t-wave inversions, new bundle-branch blocks. No points for first degree AV block, benign early repolarization, or QT-prolongation Two points for ST-depression A stands for Age >65 gets two points 45-64 gets one point R stands for Risk factors Hypertension, hyperlipidemia, diabetes, obesity, family history, smoking, previous MI, previous CABG, stroke, peripheral arterial disease 1-2 risk factors get 1 point More than two risk factors gets two points T stands for Troponin 1-3x upper limit of normal gets one point >3x upper limit of normal gets two points This gives you a score between zero and ten 0-3 points, patients have a ~2% chance of an adverse event These patients likely go home 4-6 points, patients have a ~20% chance of an adverse event These patients get admitted or expedited outpatient stress test/echo 7-10 points, patients have a ~60% chance of an adverse event Admit and call cardiology. These patients likely get catheterized References Backus BE, Six AJ, Kelder JC, Bosschaert MA, Mast EG, Mosterd A, Veldkamp RF, Wardeh AJ, Tio R, Braam R, Monnink SH, van Tooren R, Mast TP, van den Akker F, Cramer MJ, Poldervaart JM, Hoes AW, Doevendans PA. A prospective validation of the HEART score for chest pain patients at the emergency department. Int J Cardiol. 2013 Oct 3;168(3):2153-8. doi: 10.1016/j.ijcard.2013.01.255. Epub 2013 Mar 7. PMID: 23465250. Laureano-Phillips J, Robinson RD, Aryal S, Blair S, Wilson D, Boyd K, Schrader CD, Zenarosa NR, Wang H. HEART Score Risk Stratification of Low-Risk Chest Pain Patients in the Emergency Department: A Systematic Review and Meta-Analysis. Ann Emerg Med. 2019 Aug;74(2):187-203. doi: 10.1016/j.annemergmed.2018.12.010. Epub 2019 Feb 2. PMID: 30718010. https://www.mdcalc.com/calc/1752/heart-score-major-cardiac-events Summarized by Jeffrey Olson, MS4 | Edited by Jorge Chalit, OMS4 Donate: https://emergencymedicalminute.org/donate/

In this episode of Quah (Q & A), Sal, Adam & Justin coach three Pump Heads via Zoom. Mind Pump Fit Tip: 3 food additives that are killing your health. (2:13) Plugged vs unplugged. (26:10) Sal's talk at the Peptide World Congress. (36:07) The effects of Acetaldehyde on the gut. (38:40) How family members can hinder one's recovery. (41:38) Two words to define each decade of life. (47:13) Mind Pump is looking for trainers. Apply today! (1:00:21) #ListenerLive question #1 – Is there anyone here with experience, either having been injured or having helped people recover from this type of ongoing trauma? (1:01:36) #ListenerLive question #2 – What program would you guys recommend for teenagers? (1:12:23) #ListenerLive question #3 – Am I correct to allow my core to be such a limiting factor when doing squats, or is my fear the real culprit? (1:27:38) Related Links/Products Mentioned Ask a question to Mind Pump, live! Email: live@mindpumpmedia.com Visit Pre-Alcohol by ZBiotics for an exclusive offer for Mind Pump listeners! ** Promo code MINDPUMP25 for 15% off first-time purchasers on either one-time purchases, (3, 6, 12-packs) or subscriptions (6, 12-pack) ** Visit Rock Recovery Center for the exclusive offer for Mind Pump listeners! ** Ben and Tom know firsthand the struggles of addiction and alcoholism. With years of experience helping thousands of individuals, they offer a free consultation call to discuss your situation. Whether you're personally battling addiction or have a loved one in need of help, they're here to guide you toward the support you need. By filling out the form and scheduling your call, you'll also be entered for a chance to win a free 60-day scholarship at Rock Recovery Center, their premier treatment center in West Palm Beach, Florida. Don't wait—take the first step today. ** Special MAPS Longevity Launch: ** Code 50LONG for $50 off, now $97 (regularly $147). Bonuses: Forum access for a year ($97), Post-Launch Kickoff Zoom call ($97). Expires on 6/22 (30-day money-back guarantee). **June Special: Shredded Summer Bundle or Bikini Bundle 50% off! ** Code JUNE50 at checkout ** Scientist's Study Led FDA to Ban Red No. 3 Food Dye. Yet He Says It Is Safe Distinct Gut Microbiota Signatures in Mice Treated with Commonly Used Food Preservatives Processed meat and colorectal cancer: a review of epidemiologic and experimental evidence Ultra-Processed Food Consumption and Mental Health: A Systematic Review and Meta-Analysis of Observational Studies Mind Pump Personal Training – Apply today! Get your free Sample Pack with any “drink mix” purchase! Also, try the new LMNT Sparkling — a bold, 16-ounce can of sparkling electrolyte water: Visit DrinkLMNT.com/MindPump MAPS Prime Pro Webinar The Dunphy Squat | At Home Squat Variation – YouTube Mind Pump Podcast – YouTube Mind Pump Free Resources People Mentioned Michael Israetel (@drmikeisraetel) Instagram Thomas Conrad (@realrecoverytalktom) Instagram Ben Bueno (@realrecoverytalkben) Instagram  

This episode discusses findings from a recent systematic review preprint, examining how the embryonic germ layer origin of various cancers may relate to differences in therapy response. Drawing on evidence from clinical trials and mechanistic studies, we explore patterns observed among mesoderm-, endoderm-, and ectoderm-derived tumors.The conversation highlights how integrating developmental biology concepts into oncology may help inform treatment decisions and research design. This episode is intended for students, researchers, and clinicians interested in cancer biology, translational research, and personalized medicine.Please note: The views of this podcast represent those of my guest and I, and do not constitute medical advice, recommendations or consultations. Please see a state certified and board certified professional for medical, advice and recommendations. We disclaim any loss in any way.Link to Preprint: Embryonic Germ Layer Origin as a Potential Determinant of Cancer Therapy Response: A Systematic Review and Meta-Analysis of Contemporary Evidence | medRxivNote: Some of this episode's production involved the use of AI.

Once the most popular graft choice for ACL reconstruction surgery, hamstring autograft has recently fallen out of favor for a variety of concerns including a higher graft rupture rate in younger athletes and concerns over graft diameters that tend to run smaller. However, what does the best level evidence actually say about hamstring autograft's long-term performance versus the current gold-standard, patellar tendon autograft? Dr. Derrick Knapick, MD joins us from Washington University School of Medicine in St. Louis to discuss his study looking at this question.    

Train the Best. Change EMS.Howdy, y'all, I'm Dr Jeff Jarvis, and I'm the host of the EMS lighthouse project podcast, but I'm also the medical director for the new EMS system we're building in Fort Worth Texas. We are looking for an experienced critical care paramedic who is an effective and inspiring educator to lead the initial and continuing training and credentialing of a new team of Critical Care Paramedics who will be responding to our highest acuity calls. The salary is negotiable but starts between $65,000 and $80,000 a year for this office position. Whether y'all wear cowboy boots or Birkenstocks, Fort Worth can be a great place to live and work. So if you're ready to create a world-class EMS system and change the EMS world with us, give us a call at 817-953-3083, take care y'all.The next time you go to intubate a patient, should you give the sedation before the paralytic or the paralytic before the sedative? Does it matter? And what the hell does Bayes have to do with any of this? Dr Jarvis reviews a paper that uses Bayesian statistics to calculate the association between drug sequence and first attempt failure. Then he returns to Nerd Valley to talk about how to interpret 95% confidence intervals derived from frequentists statistics compared to 95% credible intervals that come from Bayesian statistics. Citations:1.     Catoire P, Driver B, Prekker ME, Freund Y: Effect of administration sequence of induction agents on first‐attempt failure during emergency intubation: A Bayesian analysis of a prospective cohort. Academic Emergency Medicine. 2025;February;32(2):123–9. 2.     Casey JD, Janz DR, Russell DW, Vonderhaar DJ, Joffe AM, Dischert KM, Brown RM, Zouk AN, Gulati S, Heideman BE, et al.: Bag-Mask Ventilation during Tracheal Intubation of Critically Ill Adults. N Engl J Med. 2019;February 28;380(9):811–21.3.     Greer A, Hewitt M, Khazaneh PT, Ergan B, Burry L, Semler MW, Rochwerg B, Sharif S: Ketamine Versus Etomidate for Rapid Sequence Intubation: A Systematic Review and Meta-Analysis of Randomized Trials. Critical Care Medicine. 2025;February;53(2):e374–83.

Dr. Aditi Nerurkar discusses the neuroscience behind stress—and offers actionable tips for building your resilience.— YOU'LL LEARN — 1) The major myth that leads to burnout 2) The rule of two for building healthier habits 3) How to feel less stressed in one minuteSubscribe or visit AwesomeAtYourJob.com/ep1065 for clickable versions of the links below. — ABOUT ADITI — Dr. Aditi Nerurkar is a Harvard stress expert, internationally recognized speaker, and national television correspondent with an expertise in stress, burnout, resilience and mental health. Her book The 5 Resets: Rewire Your Brain and Body for Less Stress and More Resilience is a “must read” by Adam Grant and Malcolm Gladwell's Next Big Idea Club and “best new book” by the New York Post. Named “100 Women to Know in America,” her work has been featured in The New York Times, The Washington Post, Good Morning America, The Today Show and NPR. She is also a frequent keynote speaker with talks at the Forbes 30 Under 30 Summit and other events.• Book: The 5 Resets: Rewire Your Brain and Body for Less Stress and More Resilience • Test: Your Stress Score • Website: DrAditi.com— RESOURCES MENTIONED IN THE SHOW — • Tool: Holmes and Rahe stress scale • Study: “Association of wearable device-measured vigorous intermittent lifestyle physical activity with mortality” by Emmanuel Stamatakis, et al. • Study: “Effects of Exercise on Patients with Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis” by Jiale Peng, Yuling Yuan, Yuanhui Zhao, and Hong Ren • Past episode: 996: Tackling Work Stressors and Transitions with Dr. Tessa West — THANK YOU SPONSORS! — • Strawberry.me. Claim your $50 credit and build momentum in your career with Strawberry.me/Awesome• Quince. Get free shipping and 365-day returns on your order with Quince.com/AwesomeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode, I sat down with Dr. Suzette Sutherland, a seasoned urologist who recently transitioned from the University of Washington to a large urology group in Arizona. Dr. Sutherland shares her expertise on treating overactive bladder (OAB) and the latest innovation in neuromodulation therapies, specifically focusing on the efficacy and safety of tibial nerve stimulation. We discuss the evolution of treatment guidelines, the pros and cons of various therapies, including medications, Botox, and sacral nerve stimulation, and dive deep into the promising results from the FDA-approved Revi device from BlueWind. Dr. Sutherland also sheds light on patient selection, procedural details, and patient compliance, while offering insights into the future of OAB treatments.For information on the REVI   https://bluewindmedical.com/Timeline:00:30 Introduction and Guest Introduction01:10 Understanding Overactive Bladder and Treatment Options02:19 Tibial Nerve Stimulation: A New Approach02:40 Changes in Treatment Guidelines05:57 Mechanism of Tibial Nerve Stimulation09:38 Implantable Tibial Nerve Stimulation Devices13:39 Patient Experience and Compliance17:54 Comparing Neuromodulation Devices25:37 Comparing Revi and Eco Devices26:32 Understanding Device Placement and Stimulation Frequency27:18 Battery Life and Replacement Concerns29:33 New Devices on the Horizon30:03 Meta-Analysis of Tibial Nerve Stimulation32:49 Patient Choices: Sacral Nerve Stimulation vs. Tibial Nerve Stimulation38:22 The Role of Botox in Bladder Treatment46:14 Challenges and Innovations in Urogynecology

Send us a textActive Treatment vs Expectant Management of Patent Ductus Arteriosus in Preterm Infants: A Meta-Analysis.Buvaneswarran S, Wong YL, Liang S, Quek SC, Lee J.JAMA Pediatr. 2025 May 27:e251025. doi: 10.1001/jamapediatrics.2025.1025. Online ahead of print.PMID: 40423988 Free PMC As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

In this episode of the Movement Logic Podcast, Sarah explores the commonly held belief that any amount of exercise is better than none. Using recent research, she discusses the benefits of minimal exercise on cardiovascular health and longevity but also highlights the limitations of this advice. She emphasizes the need for strength training and power exercises to meet the comprehensive physical needs of the body, especially as we age. Additionally, she discusses the socioeconomic barriers to regular exercise and suggests systemic changes to make meaningful physical activity more accessible to everyone.Sign up for the Wait List for our Bone Density Course!00:03 The Common Exercise Advice: Just Do Something02:01 Scientific Evidence Supporting Minimal Exercise06:58 Limitations of Minimal Exercise10:01 Strength Training and Its Importance16:35 Challenges and Practical Solutions for Exercise22:12 Conclusion and Final ThoughtsReferences:Dose-response associations between accelerometry measured physical activity and sedentary time and all cause mortality: systematic review and harmonised meta-analysisPhysical Activity, All-Cause and Cardiovascular Mortality, and Cardiovascular DiseaseAssociation of wearable device-measured vigorous intermittent lifestyle physical activity with mortalityResistance Training and Mortality Risk: A Systematic Review and Meta-AnalysisEffects of Resistance Training Frequency on Measures of Muscle Hypertrophy: A Systematic Review and Meta-Analysis

Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association's four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 25 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians and health care professionals, Diabetes Core Update   discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting. Welcome to diabetes core update where every month we go over the most important articles to come out in the field of diabetes. Articles that are important for practicing clinicians to understand to stay up with the rapid changes in the field.  This issue will review: 1.    Intensive Blood-Pressure Control in Patients with Type 2 Diabetes 2.    Cardioprotective Glucose-Lowering Agents and Dementia Risk A Systematic Review and Meta-Analysis 3.    A Randomized Trial of Automated Insulin Delivery in Type 2 Diabetes 4.    Screening for Metabolic Dysfunction–Associated Steatotic Liver Disease–Related Advanced Fibrosis 5.    Risk of Urogenital Infections in People With Type 2 Diabetes Initiating SGLT2i Versus GLP-1RA in Routine Clinical Care   For more information about each of ADA's science and medical journals, please visit Diabetesjournals.org. Hosts: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Chair-Department of Family Medicine, Abington Jefferson Health

If you've heard anything about the study of human personality, you've probably heard about the “big five.” This is a framework that attempts to characterize human personality in terms of five broad factors or dimensions—neuroticism, extraversion, openness, conscientiousness, and agreeableness. The big five framework has been enormously influential, generating heaps and heaps of data, and study after study on the stability of personality, on the factors that shape our personalities, on how our personalities predict success and satisfaction. But is the big five really the best we can do? What does it miss? What does it mask? Where should the science of human personality go next? My guest today is Dr. René Mõttus. René is Professor of Psychology at the University of Edinburgh, and a leading researcher in the scientific study of human personality. He's also one of the hosts of the Personality Psychology Podcast. Here, René and I talk about the history and colossal success of the “big five.” We consider whether personality is ultimately rooted in our biology—and, if so, how. We dwell on each of the five factors and dig into the facets and nuances within them. These are, actually, technical terms in the field for the more granular aspects of personality that sit within each of these broad dimensions. We talk about personality change across the lifespan, and what factors seem to be driving it. We talk about personality and occupation, personality and birth order, personality and gender. Along the way, René and I touch on the Myers-Briggs; an alternative to the Big 5 known as the HEXACO model; the power of explicit questionnaires over experiments; the concept of "personality age"; the social investment theory; honesty, humility, humor, jealousy; life satisfaction; gene-environment correlations; and why evolutionary stories about personality seem to fail. Alright friends, I think you'll like this one. On to my conversation with Dr. René Mõttus. Enjoy!   A transcript of this episode will be posted soon.   Notes and links 5:30 – For a popular discussion of the Myers-Briggs and other personality tests, see here. For a book-length treatment of the history of the Myers-Briggs test, see here. 11:30 – For Dr. Mõttus's preprint on “personality age,” see here. 17:00 – For our episode on animal personality with Dr. Kate Laskowski, see here. 18:00 – For Dr. Daniel Nettle's book on personality, see here. 22:00 – See Dr. Mõttus's blog post on the genetic basis of personality. 25:00 – For our episode with Dr. Eric Turkheimer about IQ, see here. For Dr. Turkheimer's “phenotypic null hypothesis” about personality, see here. 28:00 – For a theoretical paper by Dr. Mõttus and colleagues about “carving personality at its joints” and “big few models”—among many other issues—see here. 31:00 – See here for a classic overview of the “big five.” 38:00 – For an overview of the predictive power of the “big five,” see here. 40:00 – On the topic of “nuances,” see Dr. Mõttus's recent co-authored paper here. 43:00 – For the study by Dr. Mõttus and colleagues of the personality profiles of different occupations, see here. For an online tool that allows you to explore the data, see here. For an online tool that matches your personality with the personality profiles of different occupations, see here. 47:00 – A classic paper on the HEXACO model of personality. 51:00 – An example of a recent effort to map out the “facets” of personality. 1:11:00 – For a study on the possibility of gene-environment correlations in the area of music, see here. For the study by Dr. Mõttus and colleagues on children “becoming less alike” through adolescence, see here. 1:18:00 – For a classic statement of the “five factor theory,” see here. 1:20:00 – The Wikipedia page for the idea of the “gloomy prospect” is here. This is also the name of Dr. Turkheimer's newsletter. 1:22:00 – The latest installment in the longstanding debate about birth order and personality. 1:27:00 – A paper comparing the “five factor” and “social investment” accounts of personality development. 1:33:00 – For a recent paper by Dr. Mõttus and colleagues on personality and gender, see here. 1:38:00 – A research article on the Estonian Biobank.   Recommendations ‘Life Events and Personality Change: A Systematic Review and Meta-Analysis,' by Bühler et al. ‘Personality stability and change: A meta-analysis of longitudinal studies,' by Bleidorn et al. ‘Choosing prediction over explanation in psychology: Lessons from machine learning,' by Yarkoni & Westfall   Many Minds is a project of the Diverse Intelligences Summer Institute, which is made possible by a generous grant from the John Templeton Foundation to Indiana University. The show is hosted and produced by Kensy Cooperrider, with help from Assistant Producer Urte Laukaityte and with creative support from DISI Directors Erica Cartmill and Jacob Foster. Our artwork is by Ben Oldroyd. Our transcripts are created by Sarah Dopierala. Subscribe to Many Minds on Apple, Stitcher, Spotify, Pocket Casts, Google Play, or wherever you listen to podcasts. You can also now subscribe to the Many Minds newsletter here! We welcome your comments, questions, and suggestions. Feel free to email us at: manymindspodcast@gmail.com.  For updates about the show, visit our website or follow us on Twitter (@ManyMindsPod) or Bluesky (@manymindspod.bsky.social).

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Prevalence, Risk Factors, and Prognosis for Fontan-Associated Liver Disease: A Systematic Review and Exploratory Meta-Analysis.

  In this Q&A episode, Dr. Rebecca Dekker answers questions submitted by EBB Pro Members—each exploring a different facet of evidence-based maternity care.   First, she explores the latest evidence on early induction for gestational hypertension, including findings from the WILL trial and other recent studies. What are the real risks and benefits of inducing labor at 37 or 38 weeks for gestational hypertension? And how should families weigh these decisions with their providers?   Next, Dr. Dekker shares new insights into the effectiveness of acupuncture and acupressure for labor pain, anxiety, and Cesarean recovery. From systematic reviews to randomized trials, the data is growing!   Finally, she looks into the evidence on interpregnancy intervals. What does the research say about the risks associated with short or long gaps between pregnancies? And how might this information apply to those who are pregnant again after a five-year or more break?   (00:00) Intro to Mini Q&A and EBB Pro Membership (02:17) Early Induction for Gestational Hypertension – What the Research Says (06:20) WILL Trial Findings and Recommendations from ACOG and NICE (08:23) Outcomes at 37 vs. 38 Weeks – Cesareans, NICU, and Respiratory Distress (10:15) Balancing Induction Timing and Risks of Continuing Pregnancy (11:03) Acupuncture and Acupressure – New Research and Applications (12:41) Studies on Pain, Anxiety, and Nausea During Labor and Cesareans (14:46) Acupuncture and Cesarean Recovery – Mobility and Pain Management (16:54) Interpregnancy Intervals – Definitions and Research Challenges (19:39) Risks of Short and Long Pregnancy Spacing (23:22) Global Perspectives and Meta-Analysis on Birth Outcomes (26:49) Public Health Implications and Final Thoughts   View the full list of resources and references on ebbirth.com.   For more information about Evidence Based Birth® and a crash course on evidence based care, visit www.ebbirth.com. Follow us on Instagram and YouTube! Ready to learn more? Grab an EBB Podcast Listening Guide or read Dr. Dekker's book, "Babies Are Not Pizzas: They're Born, Not Delivered!" If you want to get involved at EBB, join our Professional membership (scholarship options available) and get on the wait list for our EBB Instructor program. Find an EBB Instructor here, and click here to learn more about the EBB Childbirth Class.

Send us a textThis recording features audio versions of June 2025 Journal of Vascular and Interventional Radiology (JVIR) abstracts:Comparison of Bypass Surgery versus Endovascular Interventions for Peripheral Artery Disease through Systematic Review and Meta-Analysis of Randomized Controlled Trials ReadThe Incidence and Consequences of Endovascular Technical Failure in Patients with Chronic Limb-Threatening Ischemia: Results from the Best Endovascular versus Best Surgical Therapy in Patients with Critical Limb-Threatening Ischemia (BEST-CLI) Trial ReadComparative Radiologic Response Assessment after Transarterial Chemoembolization, Percutaneous Ablation, and Multimodal Treatment: Radiologic-Pathologic Correlation in 81 Tumors ReadBreast Cancer Recurrence after Cryoablation in Patients Who Are Poor Surgical Candidates or Who Refuse Surgery ReadKetamine/Midazolam versus Fentanyl/Midazolam Sedation for Interventional Radiology Procedures: A Prospective Registry ReadPortal and Hepatic Vein Embolization versus Portal Venous Embolization Alone in Cirrhotic and Noncirrhotic Swine: A Pilot Study ReadAssessment of Catheter-Directed Thrombolysis and Histotripsy Treatment for Deep Vein Thrombosis ReadExpanding Global IR Outreach to Address Postpartum Hemorrhage in Kenya Using Geospatial Analytic Mapping ReadJVIR and SIR thank all those who helped record this episode. To sign up to help with future episodes, please contact our outreach coordinator at millennie.chen.jvir@gmail.com.  Host and audio Editor:Sonya Choe, University of California Riverside School of MedicineOutreach coordinator:Millennie Chen, University of California Riverside School of MedicineAbstract readers:Marc Attalla, University of California Riverside School of MedicineAgnes Manish, Loma Linda University School of MedicineClare Necas, Western University of Health Sciences, College of Osteopathic MedicineGavin Shu, University of California San Francisco School of MedicineMark Oliinik, Loma Linda University School of MedicineAbhisri Ramesh, George Washington School of Medicine and Health SciencesAndrew Sasser, University of Miami Miller School of Medicine Sakeena Siddiq, Western University of Health Sciences, College of Osteopathic MedicineSIR thanks BD for its generous support of the Kinked Wire.Read more about about interventional radiology in IR Quarterly magazine or SIR's Patient Center.Support the show

Kann vegane Ernährung (im Ayurveda) langfristig wirklich funktionieren? Oder wird sie am Ende mehr schaden als helfen? In dieser Folge erwarten dich echte Antworten und 3 grundlegende Vegan-Hacks für jeden Dosha-Typ. Für bessere Verdauung und Nährstoffversorgung – evidenzbasiert und ayurvedisch fundiert.Was dich in dieser Folge erwartet: (Wie) funktioniert vegane Ernährung im Ayurveda? Warum die Antwort so individuell ist, wie dein du. Proteinzufuhr und typgerechte Auswahl und Kombination pflanzlicher Proteinquellen Kritische Nährstoffe, typgerechte Lebensmittel und wann und ob Nahrungsergänzungsmittel erforderlich sind Ghee, Honig & Co: Tierische Ayurveda-Lebensmittel und typgerechte Alternativen Die ethische Perspektive & Qualität tierischer LebensmittelKonntest du etwas für dich mitnehmen? Dann würde ich mich riesig über deinen Like freuen.

Join JACC Editor in Chief Harlan Krumholz, MD, SM, as he speaks about this ACC.25 presentation published in JACC. This fascinating study by Rohan Khera et al independently analyzed patient-level data from the SURMOUNT trials of tirzepatide for obesity. The study revealed striking individual variability in weight loss and metabolic response, even to a highly effective therapy—an insight powerfully illustrated through waterfall plots. Reviewers praised the transparent, sponsor-independent approach and the study's contribution to precision medicine, though they noted it was descriptive rather than predictive, underscoring the need for future research to identify what drives differential treatment response.

This week we discuss the new leader that was shown this week.We also cover last weeks meta and talk about next week and what we would be running. Links --------- Youtube: https://www.youtube.com/channel/UCRX-7c7R0_FlTZZ2Vtdi_9Q Willow Links: https://wlo.link/@planningphasesyndicate Facebook: https://www.facebook.com/Planning-Phase-Syndicate-102792741982012 Twitch: https://www.twitch.tv/planningphasesyndicate Patreon: https://www.patreon.com/PlanningPhaseSyndicate Discord: https://discord.gg/eqxnTxDFAr Podcast: https://planningphasesyndicate.podbean.com Paypal: https://paypal.me/ppsyndicate --------- https://melee.gg/Tournament/View/286294 https://www.melee.gg/Tournament/View/304275 https://melee.gg/Tournament/View/304088 https://melee.gg/Tournament/View/287101 https://melee.gg/Tournament/View/282648

Send us a textPrenatal Cannabis Use and Neonatal Outcomes: A Systematic Review and Meta-Analysis.Lo JO, Ayers CK, Yeddala S, Shaw B, Robalino S, Ward R, Kansagara D.JAMA Pediatr. 2025 May 5:e250689. doi: 10.1001/jamapediatrics.2025.0689. Online ahead of print.PMID: 40323610As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Dr. Rajesh Rao sits down with Dr. Sophie J. Bakri and medical student Marie-Michele Macaron to discuss their systematic Review and meta-analysis on the efficacy and safety of anti-VEGF and panretinal photocoagulation for the treatment of proliferative diabetic retinopathy. From their Ophthalmology Retina article, “Anti-VEGF Injections vs. Panretinal Photocoagulation Laser Therapy for Proliferative Diabetic Retinopathy: A Systematic Review and Meta-Analysis.” Anti-VEGF Injections vs. Panretinal Photocoagulation Laser Therapy for Proliferative Diabetic Retinopathy. Macaron, Marie-Michele et al. Ophthalmology Retina, Volume 9, Issue 2, 105 - 121.

Title: Journal Club Series Episode 13-  Systematic review and meta-analysis Target Audience This activity is directed to physicians, medical students, nurse practitioners, nurses, and physician assistants. Objectives: Upon completion of this activity, participants should be able to: •      Conduct systematic reviews and apply proper methodologies. •      Perform meta-analyses and utilize appropriate techniques.  Course Directors: Tony R. Tarchichi MD — Associate Professor, Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center (UPMC.) Paul C. Gaffney Division of Pediatric Hospital Medicine. No relationships with industry relevant to the content of this educational activity have been disclosed. Mary Lou Klem PhD, MLIS — Assistant Director for Advanced Information Support, University of Pittsburgh School of Medicine, Health Sciences Library System No relationships with industry relevant to the content of this educational activity have been disclosed. Conflict of Interest Disclosure: No other planners, members of the planning committee, speakers, presenters, authors, content reviewers and/or anyone else in a position to control the content of this education activity have relevant financial relationships to disclose. Accreditation Statement: In support of improving patient care, the University of Pittsburgh is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.  The University of Pittsburgh School of Medicine designates this enduring material activity for a maximum of 0.75 AMA PRA Category 1 CreditsTM. Physicians should only claim credit commensurate with the extent of their participation in the activity. Other health care professionals will receive a certificate of attendance confirming the number of contact hours commensurate with the extent of participation in this activity. Disclaimer Statement: The information presented at this activity represents the views and opinions of the individual presenters, and does not constitute the opinion or endorsement of, or promotion by, the UPMC Center for Continuing Education in the Health Sciences, UPMC / University of Pittsburgh Medical Center or Affiliates and University of Pittsburgh School of Medicine.  Reasonable efforts have been taken intending for educational subject matter to be presented in a balanced, unbiased fashion and in compliance with regulatory requirements. However, each program attendee must always use his/her own personal and professional judgment when considering further application of this information, particularly as it may relate to patient diagnostic or treatment decisions including, without limitation, FDA-approved uses and any off-label uses. Released 4/15/2025,  Expires 4/15/2028 The direct link to the course is provided below: https://cme.hs.pitt.edu/ISER/app/learner/loadModule?moduleId=25796&dev=true  

Die meisten achten beim Krafttraining auf Wiederholungen, Gewichte und Trainingspläne – aber was ist mit der Pause dazwischen? In dieser Folge erfährst Du, warum die Satzpause kein Lückenfüller, sondern ein entscheidender Erfolgsfaktor ist. Du bekommst konkrete Empfehlungen, wie lange Du zwischen den Sätzen pausieren solltest – je nachdem, ob Du Muskeln aufbauen, stärker werden oder Fett abbauen willst.Außerdem: Warum sich meine eigenen Empfehlungen über die Jahre verändert haben – und wie Du aus Deinem Training mit einem simplen Timer mehr rausholst.____________*WERBUNG: Infos zum Werbepartner dieser Folge und allen weiteren Werbepartnern findest Du hier.____________Vielen Dank für Dein Vertrauen. Hier sind ein paar weitere Wege, wie ich Dich unterstützen kann.​Kostenlos:Email: #DRNBLBR WeeklyInstagram: @fitnessmitmark​​​Kostenpflichtig:Bücher: Dranbleiben! und Looking Good Naked​​Workouts: #DRNBLBR Bodyweight Circle​Persönliche Betreuung: MarathonFitness Online-Coaching​____________Quellen:Grgic, J. et al. (2022). Effects of Inter-Set Rest Intervals on Resistance Training Outcomes: A Systematic Review and Meta-Analysis. Sports Medicine.Henselmans, M. & Schoenfeld, B.J. (2014). The effect of inter-set rest intervals on resistance exercise-induced muscle hypertrophy. Sports Medicine.Schoenfeld, B.J. et al. (2016). Longer Interset Rest Periods Enhance Muscle Strength and Hypertrophy in Resistance-Trained Men. J. Strength Cond Res.de Salles, B.F. et al. (2009). Rest interval between sets in strength training. Sports Medicine.____________

Our last poster is titled Outcomes and Return to Sport Following Arthroscopic Bankart Repair for Anterior Shoulder Instability in Contact versus Non-contact Athletes: A Systematic Review and Meta-Analysis.  We've spoken a lot about the surgical treatment for anterior shoulder instability on this podcast – most recently with Dr. Brian Lau.  That is episode #48 and 49 if you want to check it out.This study focused on outcomes of arthroscopic Bankart repair for the treatment of anterior shoulder instability, specifically comparing outcomes in contact athletes versus noncontact athletes.  This systematic review included 18 studies with 1-year minimum follow-up.The authors found that contact and noncontact athletes had similar rates of return to sport as well as similar rates of return to preinjury level of play.  However, they also found that contact athletes demonstrated significantly greater rates of recurrent instability, at 28% compared to 8% in noncontact athletes.  Contact athletes also demonstrated significantly greater need for revision surgery, at 12% compared to 3% in noncontact athletes.

Full article: NPV of Biparametric and Multiparametric Prostate MRI: A Comparative Systematic Review and Meta-Analysis Kamyar Ghabili, MD, discusses the AJR article by Salinas-Miranda et al. that evaluates available comparative studies of the NPV of biparametric MRI and multiparametric MRI of the prostate.

Send us a textCord Blood Treatment for Children With Cerebral Palsy: Individual Participant Data Meta-Analysis.Finch-Edmondson M, Paton MCB, Webb A, Reza Ashrafi M, Blatch-Williams RK, Cox CS Jr, Crompton K, Griffin AR, Kim M, Kosmach S, Kurtzberg J, Nouri M, Ri Suh M, Sun J, Zarrabi M, Novak I.Pediatrics. 2025 Apr 11:e2024068999. doi: 10.1542/peds.2024-068999. Online ahead of print.PMID: 40210215As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Spring is the perfect time to shake up your routine. In this episode, Professor Tim Spector and Dr. Federica Amati reveal seven delicious, science-backed foods that help cool the flame of chronic inflammation. Whether you're dealing with bloating, aching joints, or low energy, this episode is packed with easy, gut-friendly tips to help you feel your best this season. Tim and Federica begin by explaining what inflammation really is and when it becomes a problem. Then, they'll introduce seven anti-inflammatory foods that are as powerful as they are delicious. From cruciferous vegetables to fermented surprises, these everyday ingredients can help you build a more resilient, healing diet.  Finally, they offer a roadmap for long-term change. Tim and Fed each share one small but powerful shift to reduce inflammation over four timelines - what you can do today, this week, this month, and throughout the year - to create habits that truly stick.

How much can a change in diet influence symptoms of mental health disorders? Why are a diversity of plants and whole foods so important to include, and ultra processed foods so important to remove? Why are inflammation and microbe diversity in the gut so key to this question? What does this research mean for the life-style medicine movement and to world food policy?In this episode we have the exploding new field of nutritional psychiatry to get to grips with, that is the way our diet can influence and even treat mental health conditions. We're going to be discussing the historical separation of mind and body by science, which has led to scepticism that diet could influence mental health outcomes; the new understanding of the importance of diversity in our microbiome and inflammation to our mood and mental state; our main topic which is going to be the radical results of recent trials showing large changes in cognitive and mental health outcomes when diet is altered; we'll get into the foods that can bring about that change and why they work; and we're going to be getting into the reasons for the broken industrialised food environment that has contributed to the current mental health epidemic in the west.Fortunately, to understand this complex new field, our guest today is the very scientist that risked her reputation to conduct the first trials, facing considerable pushback, only to shift the consensus remarkably quickly with some top science, Felice Jacka. She is the Deakin University Distinguished Professor of Nutritional Psychiatry in Melbourne, the founder and director of the Food & Mood Centre, and of the International Society of Nutritional Psychiatry; She has been cited in over 100 institutional directives for food policy including the World Health Organization and UNICEF; and she is also the author of two books on this for the general public, the children's book “There's a Zoo in my Poo” and for adults “Brain Changer: How diet can save your mental health” which we'll be covering today. Her impact has been so high on public health that in 2021 she was awarded the Order of Australia for her services to nutritional psychiatry.What we discuss:00:00 Intro08:50 The historic separation between mental and physical health. 10:35 People with mental health die about 20 years earlier. 13:30 The connection between the immune system and mental health. 16:20 New microbiome & chronic inflammation research's influence on psychiatry. 20:00 Epigenetics, mitochondria (energy generation) & neurotransmitter influences. 21:15 Gut brain axis & oxidative stress response.33:30 The SMILES trial results and their integration into the consensus. 38:30 Using the Press to shorten the usual 20 year gap between results and policy change. 43:00 Industrialised food is the leading cause of chronic disease & biodiversity loss. 45:00 ‘We're not going to tell people what to eat': the food lobby's ‘nanny state' argument. 50:00 Soil depletion and the soil microbiome. 50:50 The life-style psychiatry movement: Diet, sleep and exercise. 01:05:30 Take out ultra-processed foods - even the nutritionally balanced ones. 01:12:30 Cognitive ability and memory reduced by processed foods. 01:14:45 Nutritional and energetic equivalent foods have totally different outcomes for the microbiome. 01:19:15 Put in a variety of plants - 30 a week. 01:20:20 The mediterranean diet. 01:24:50 Polyphenol science so far. 01:27:00 Emulsifiers and artificial sugars - the mucosal lining of the gut. 01:30:15 Fermented foods - the waste products of the bacteria are beneficial. References:Felice Jacka, “Brain Changer: The Good Mental Health Diet”Felice Jacka, “There's a Zoo in my Poo”Melissa Lane et al, ‘Ultra‐Processed Food Consumption and Mental Health: A Systematic Review and Meta‐Analysis of Observational Studies' paperFelice Jacka' et al, ‘A randomised controlled trial of dietary improvement for adults with major depression (the 'SMILES' trial)' Paper

In this episode of Iron Culture, host Eric Trexler and guest Jake Remmert discuss a new meta regression paper focusing on per session set volume and its impact on hypertrophy and strength. They explore the nuances of per session training volume, the implications of the findings, and address common misconceptions in the fitness community. The conversation emphasizes the importance of understanding the data and its limitations while providing practical applications for training. Time Stamps: 00:00 Introduction 00:30 Jake Remmert's Background and Journey 06:18 Transition to Research and Meta-Analysis 16:24 Exploring Per Session Set Volume 23:27 Methodological Approach to the Study 26:22 Results and Practical Applications 27:33 Defining Terminology and Effect Sizes 30:10 Exploring Hypertrophy and Set Volume Relationships 33:54 Practical Recommendations for Training Volume 37:43 Understanding Variance in Data and Its Implications 46:50 Transitioning to Strength Results and Their Insights 58:55 Practical Applications and Training Adjustments 01:03:26 Volume and Recovery: Finding the Balance 01:07:08 The Importance of Frequency in Training 01:10:00 Understanding Volume and Its Impact on Performance 01:12:32 Interpreting Research: The Nuances of Meta-Analysis 01:24:43 Final Thoughts

In this podcast, Dr. Valentin Fuster discusses a recent study on the use of cardiac troponins in predicting cardiovascular disease risk, showing a modest improvement when added to traditional risk factors. While the findings suggest potential benefits in population health, he emphasizes the importance of focusing on the eight core modifiable risk factors for cardiovascular disease rather than solely relying on biomarkers like cardiac troponins.

In this episode, Dr. Ana Valenzuela, Professor of Marketing at ESADE Business School in Barcelona, discusses a meta-analysis of consumer responses to artificial intelligence (AI) over the past two decades. The conversation explores the evolving attitudes toward AI, the factors influencing consumer resistance, and strategies businesses can use to build trust in AI solutions. The research reveals nuanced perspectives on how people perceive and interact with different types of AI in various contexts.

In this episode of The Junkyard Love Podcast, we meet Wendy Cole, a 67-year-old Transition Mentor who fully transitioned after 65. Wendy shares her inner perspective from her years living as a married man and father while grappling deeply with identity, societal expectations, and secrets that visited her sleep. Wendy shares stories of how she embraced her true self later in life, and we discuss her intensive internal exploration, self-work, her time in therapy, friends along the way, meditation, Joe Dispenza, reshaping limiting beliefs, creating new identities, telling the truth, and more.Wendy invited me to think differently, and I had a great time exploring the heart and mind of this unorthodox teacher. Her story offers us deep insight into the human being's profound ability for change - at any age. Some quotes from Wendy:"The greatest freedom I've discovered wasn't physical—it was mental. Changing my thoughts and beliefs changed everything.""If you've never looked in the mirror and questioned your actual gender identity, 'I should have been a boy,' or 'I should have been a girl,' if you've never done that, I don't expect you to fully understand the depth of the distress.""My therapist challenged every one of my thoughts, every one of my beliefs in myself.""When you're able to finally align your outside with your inside, the sense of peace and joy is indescribable.""Every limiting belief I confronted was like shedding a layer; underneath, I found who I truly was."Guest Bio - Wendy Cole:Wendy Cole is a Transition Mentor dedicated to supporting individuals navigating significant life changes. Having personally transitioned around age 67, Wendy uses her transformative journey and deep empathy to guide clients toward embracing their authentic selves. Her mentoring approach combines mindfulness, visioning, and intentional energy shifts, helping others confront fears and discover joy in their true identities. Wendy believes deeply in the power of inner work, emphasizing that the mental and emotional aspects of transition are just as vital as the physical ones. Through coaching, speaking engagements, and sharing her powerful story, Wendy inspires individuals to embrace their journeys boldly and authentically.Connect with Wendy:Website: wendycolegtm.netLinkedIn: linkedin.com/in/wendy-cole-gtmYouTube: youtube.com/@wendycole8326Demystifying The Transgender JourneyWebsite:  https://thetransgenderjourney.comOn YouTube: https://youtube.com/@thetransgenderjourney On Podbean: https://demystifyingthetransgenderjourney.podbean.com/If you enjoyed this episode of The Junkyard Love Podcast, drop me a subscribe!Maybe you'll enjoy some of my upcoming episodes. See ya soon with the next guest!

Join JACC Associate Editor Khurram Nasir, MBBS, FACC, and author Rohan Khera, MD, FACC, as they discuss the latest study on tirzepatide presented at ACC.25 and published in JACC. Tirzepatide, a dual GIP/GLP-1 receptor agonist, exerts pleiotropic effects on cardiometabolic health. This study evaluated its efficacy in improving cardiometabolic outcomes in individuals with T2D. An individual participant data meta-analysis was conducted, pooling data from seven Phase 3 RCTs comparing tirzepatide with placebo or standard antihyperglycemic agents. The study outcomes included cardiometabolic components of metabolic syndrome (MetS), elevated BMI, and MetS. Tirzepatide significantly reduced the odds of these abnormalities and effectively resolved MetS, with superior efficacy observed in younger individuals and those not on baseline SGLT2is. These findings support the potential of tirzepatide to improve cardiometabolic health in T2D.

In this episode of Iron Culture, hosts Eric Helms and Eric Trexler engage in a lively discussion with Dr. James Steele about the evolving landscape of sports science, particularly focusing on the critiques of periodization and the importance of scientific theory in exercise research. They explore the philosophical underpinnings of scientific inquiry, the challenges of conducting robust research, and the implications of recent studies on training effects. The conversation emphasizes the need for a more theory-driven approach in exercise science to enhance the validity and applicability of research findings. In this conversation, James Steele and Eric Helms discuss the intricacies of designing meaningful studies in hypertrophy research, emphasizing the importance of collaboration, causal inference, and the need for high-powered studies. They explore the challenges of resistance training research, the significance of theory corroboration, and the future directions for the field. The discussion highlights the necessity of passion and purpose in research, advocating for a focus on practical applications and the importance of understanding the underlying mechanisms of training effects. Time stamps: 00:00 Introduction 03:55 The Role of Periodization in Sports Science 11:45 Critique of Periodization and Scientific Methodology 24:50 Philosophy of Science in Exercise Science 33:12 Understanding Sports Science Models 35:56 Philosophy of Science in Sports Research 40:00 The Importance of Critical Thinking 44:35 Diving into the Study 48:38 Theory of Adaptation in Resistance Training 54:47 Intervention Effects and Practical Implications 59:10 Meta-Analysis and Evidence in Sports Science 01:19:50 The Value of Individual Studies vs. Meta-Analyses 01:24:03 Understanding Causal Inference in Research 01:27:41 The Importance of Baseline Theory in Training 01:29:28 Identifying Small Effects in Research 01:33:16 The Role of Collaboration in Sports Science 01:38:38 Leveraging Data for Performance Insights 01:41:08 The Distinction Between Sports Science and Exercise Science 01:44:59 Learning from Other Fields: Causal Inference in Sports 01:47:29 Passion and Purpose in Research 01:50:02 Concluding Thoughts on the Future of Research

Oatmeal has long been considered a heart-healthy breakfast, but is it really as good for us as we think? In this episode, Jonathan and Sarah break down the great oat debate. First, they explore the different types of oats - instant, rolled, and steel-cut and how processing impacts their nutritional value. Then, they put oats to the test using continuous glucose monitors (CGMs), comparing instant to steel-cut, with and without toppings, to demonstrate how blood sugar works. Sarah also discusses wider debates around oats: Are pesticides a concern? Is oat milk as healthy as it claims? Finally, she shares the ultimate guide to choosing the healthiest oats - and for those who prefer alternatives, she's got delicious, nutrient-packed swaps to try.

In tonight's episode of Iron Culture, Eric Trexler and Eric Helms discuss various topics related to fitness, training, and research. They share personal updates, including the toll that Helms' intense training regimen is taking on his face. The discussion then shifts to the upcoming NFL combine, highlighting the impressive athletic feats expected from past combine participants. In the main segment of the show, Trexler and Helms discuss the nuances of lengthened-biased training research – more specifically, why we shouldn't give up on the strategy just because a few studies reporting non-significant results have come along. In this conversation, Trexler and Helms explore the concept of sampling error in research, emphasizing the importance of understanding some foundational statistical concepts and the need for several studies to draw reliable conclusions. They explore the challenges of uncertainty in evidence-based practice, the balance to strike between mechanistic and empirical approaches to understanding exercise and nutrition, and the resistance to change in learning. Finally, they engage in a rapid-fire Q&A session addressing a handful of fitness-related questions. The MASS crew records Iron Culture LIVE on YouTube, Monday nights at 7pm eastern time. Be sure to join us for a future episode and say hello in the live chat!  If you'd like to submit a question or topic for us to address on an upcoming episode, please use this link:  https://massresearchreview.com/ironculture Time Stamps: 00:00 Introduction and why Trexler is worried about Helms 6:40 Q&A NFL Combine analysis Trexler 2017 Fat-Free Mass Index in NCAA Division I and II Collegiate American Football Players https://pubmed.ncbi.nlm.nih.gov/27930454/  13:18 Getting into the science with Helms' upcoming MASS article on long muscle length training Burke 2006 "Fat adaptation" for athletic performance: the nail in the coffin? https://pubmed.ncbi.nlm.nih.gov/16357078/ Nunes 2022 Systematic review and meta-analysis of protein intake to support muscle mass and function in healthy adults https://pubmed.ncbi.nlm.nih.gov/35187864/ Larsen 2024 The effects of hip flexion angle on quadriceps femoris muscle hypertrophy in the leg extension exercise https://pubmed.ncbi.nlm.nih.gov/39699974/ Gschneider 2024 The effects of lengthened-partial range of motion resistance training of the limbs on arm and thigh muscle cross-sectional area https://sportrxiv.org/index.php/server/preprint/view/485/version/624 Wolf 2025 Lengthened partial repetitions elicit similar muscular adaptations as full range of motion repetitions during resistance training in trained individuals https://pubmed.ncbi.nlm.nih.gov/39959841/ Kassiano 2022 Does Varying Resistance Exercises Promote Superior Muscle Hypertrophy and Strength Gains? A Systematic Review https://pubmed.ncbi.nlm.nih.gov/35438660/ Pedrosa 2023 Training in the Initial Range of Motion Promotes Greater Muscle Adaptations Than at Final in the Arm Curl https://pubmed.ncbi.nlm.nih.gov/36828324/ 29:59 Simulating a large lengthened-bias training dataset 42:28 Some points from Trexler Trexler 2019 Acute Effects of Citrulline Supplementation on High-Intensity Strength and Power Performance: A Systematic Review and Meta-Analysis https://pubmed.ncbi.nlm.nih.gov/30895562/ 1:02:56 Mechanisms vs experimental trials (uncertainty) 1:10:15 Using Large Language Models for statistical analysis (in R) 1:21:01 Q&A Rapid fire 1: Work and energy expenditure during eccentric contractions   1:23:22 Q&A Rapid fire 2: Waited vest upsides and downsides 1:25:47 Q&A Rapid fire 3: Protein recommendations for individuals who don't train their entire body 1:29:20 Q&A Rapid fire 4: Sprint cycling for quad hypertrophy   1:35:04 Wrapping up See the entire MASS team speak at the Sports Nutrition Association Annual Conference https://sportsnutritionassociation.com/sna-annual-2025-conference/

Probably not — the incentives are too strong. But a few reformers are trying. We check in on their progress, in an update to an episode originally published last year. (Part 2 of 2) SOURCES:Max Bazerman, professor of business administration at Harvard Business School.Leif Nelson, professor of business administration at the University of California, Berkeley Haas School of Business.Brian Nosek, professor of psychology at the University of Virginia and executive director at the Center for Open Science.Ivan Oransky, distinguished journalist-in-residence at New York University, editor-in-chief of The Transmitter, and co-founder of Retraction Watch.Joseph Simmons, professor of applied statistics and operations, information, and decisions at the Wharton School at the University of Pennsylvania.Uri Simonsohn, professor of behavioral science at Esade Business School.Simine Vazire, professor of psychology at the University of Melbourne and editor-in-chief of Psychological Science. RESOURCES:"How a Scientific Dispute Spiralled Into a Defamation Lawsuit," by Gideon Lewis-Kraus (The New Yorker, 2024)."The Harvard Professor and the Bloggers," by Noam Scheiber (The New York Times, 2023)."They Studied Dishonesty. Was Their Work a Lie?" by Gideon Lewis-Kraus (The New Yorker, 2023)."Evolving Patterns of Extremely Productive Publishing Behavior Across Science," by John P.A. Ioannidis, Thomas A. Collins, and Jeroen Baas (bioRxiv, 2023)."Hindawi Reveals Process for Retracting More Than 8,000 Paper Mill Articles," (Retraction Watch, 2023)."Exclusive: Russian Site Says It Has Brokered Authorships for More Than 10,000 Researchers," (Retraction Watch, 2019)."How Many Scientists Fabricate and Falsify Research? A Systematic Review and Meta-Analysis of Survey Data," by Daniele Fanelli (PLOS One, 2009).Lifecycle Journal. EXTRAS:"Why Is There So Much Fraud in Academia? (Update)" by Freakonomics Radio (2024)."Freakonomics Goes to College, Part 1," by Freakonomics Radio (2012).