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In this episode, Joe Tumolo shares why the best medtech companies don't just build innovative products; they build relationships that drive commercialization. Drawing on more than 25 years in healthcare and life sciences, Joe reveals how founders can strengthen fundraising, hire the right sales team, navigate healthcare adoption, and create commercialization strategies that lead to lasting success. Discover why aligning with customers, investors, and partners may be the most valuable competitive advantage a startup can have.Joe Tumolo LinkedInJTSC, LLC LinkedInJTSC, LLC Website“Thinking Fast and Slow” by Daniel Kahneman Revisionist History Podcast with Malcolm Gladwell “The Undoing Project” by Michael Lewis Duane Mancini LinkedInProject Medtech WebsiteProject Medtech LinkedInThank you to our sponsors: Ward Law, Wheelhouse DMG, and JumpStart Inc.
Welcome to another insightful episode of Build a Better Agency! This week, host Drew McLellan welcomes Shawn Yeager, founder of Upshift, for a candid conversation about the seismic shifts AI is creating in the agency world. Together, they go beyond the hype and headlines, examining how agencies can genuinely commercialize AI—not just adopt new tools, but strategically redesign what they sell and how they deliver unique value in an AI-enabled marketplace. In this episode, Shawn Yeager draws on more than 30 years at the intersection of technology and business, sharing a roadmap for agency leaders. He explains the three traps many agencies fall into when adopting new technology—becoming more efficient but less profitable, becoming educated without application, and buying into platforms without changing go-to-market strategy. Drew McLellan and Shawn Yeager also break down the difference between operational AI (streamlining internal processes) and commercial AI (transforming what you offer clients), and why the latter is critical for agency growth and survival. Listeners will discover practical frameworks to evaluate service offerings, price on outcomes (even when clients aren't sure how to measure them), and proactively use AI to become indispensable advisors—not just vendors. Shawn Yeager discusses the blend of efficiency and artistry required in the modern agency, how to avoid the risks of commoditization, and why focusing on judgment, relationships, and the "decision sandwich" will separate thriving agencies from those left behind. If you're looking for actionable steps to future-proof your agency, navigate staffing shifts, or reimagine your client relationships in light of AI's rapid evolution, you won't want to miss this episode. By the end, you'll have new strategies and a fresh mindset for turning the AI revolution into your agency's greatest opportunity. A big thank you to our podcast's presenting sponsor, White Label IQ. They're an amazing resource for agencies who want to outsource their design, dev, or PPC work at wholesale prices. Check out their special offer (10 free hours!) for podcast listeners here. What You Will Learn in This Episode: Moving beyond efficiency to true AI-driven business transformation Rethinking agency offerings for an AI-enabled marketplace Shifting from billable hours to outcome-based pricing models Harnessing judgment and expertise as differentiators alongside AI tools Blending scalable, repeatable processes with bespoke, high-touch service Preparing agency staffing models for a shrinking entry-level workforce Proactively evolving client value propositions to stay ahead of commoditization
In this episode of The Syneos Health Podcast Tyler Cowan, VP, Commercial is joined by colleagues from our team in the UK, Dr. Natalia Barkalina, Medical Director and Gareth Powell, Clinical Recruitment and Retention Strategist, to discuss why patient-centered communication is essential to improving clinical trial awareness, recruitment and engagement, particularly for small and mid-size biotech companies competing for patient and investigator attention. Listen and gain a clear understanding of how integrated, patient-centered communications can help clinical trials cut through the noise, build trust with key audiences and create stronger foundations for commercialization. This podcast episode also appears on our commercial-focused podcast stream, Conversations on Commercialization. Check it out here. The views expressed in this podcast belong solely to the speakers and do not represent those of their organization. If you want access to more future-focused, actionable insights to help biopharmaceutical companies better execute and succeed in a constantly evolving environment, visit the Syneos Health Insights Hub. The perspectives you'll find there are driven by dynamic research and crafted by subject matter experts focused on real answers to help guide decision-making and investment. You can find it all at https://www.syneoshealth.com/insights-hub. Like what you're hearing? Be sure to rate and review us! We want to hear from you! If there's a topic you'd like us to cover on a future episode, contact us at podcast@syneoshealth.com.
When a company clears a key regulatory hurdle between technical validation and commercialization, the conversation begins to shift. HPQ Silicon announced August 6, 2026 that its HPQ ENDURA+ Gen4 21700 lithium ion cells achieved UN 38.3 transportation certification, enabling international shipment for customer qualification, evaluation and commercial applications. The certification supports ongoing evaluations by multiple potential buyers in the drone and defence sectors, where global defence battery demand exceeded 4 GWh in 2025, with nearly 40% generated by unmanned drone systems. This advances HPQ further toward commercial execution.Regulatory Gateway: UN 38.3 removes a key transportation hurdle, allowing HPQ ENDURA+ Gen4 cells to be shipped internationally for customer qualification, evaluation and commercial applications across drone and defence markets.Multiple Evaluations: The AA NOVA 6S3P drone battery pack, developed following work with a European drone manufacturer, and other battery platforms are being evaluated by multiple potential buyers active in the drone and defence sectors.Defence Market Scale: Global defence battery demand exceeded 4 GWh in 2025, with nearly 40% generated by unmanned drone systems, a share HPQ says has more than doubled in five years.Higher Margin Focus: Rather than pursuing high volume, lower margin markets, HPQ's strategy targets lower volume, higher margin defence and specialty applications that management believes better match its current production capacity.Commercial Timing: Customer qualification activities span evaluation, feedback, optimization and revalidation across multiple organizations. With the usual forward looking caveat, CEO Bernard Tourillon said he believes a first commercial order could occur during this quarter based on information available to him.The defence and advanced drone battery market places significant importance on incremental performance improvements. During the interview, Tourillon explained that improvements in battery performance can directly affect drone efficiency, including endurance and weight. These improvements can matter where operating time, payload capacity and performance are important.The AA NOVA 6S3P battery platform was developed following work with a European drone manufacturer, showing how customer requirements are helping shape commercial development. HPQ is focusing on applications where management believes performance differentiation can support higher margins and better align with available production capacity.The commercial opportunity extends beyond a single prospective customer. Tourillon clarified that multiple potential buyers are evaluating HPQ battery solutions at different stages. Some are in evaluation and feedback, another is in optimization and others have reached revalidation. He also confirmed that government entities are represented among the parties involved and said government activity currently involves mostly defence departments.The global military drone market is estimated at approximately US$35 billion in 2026 and projected to exceed US$109 billion by 2031, according to market research cited by HPQ, with North America accounting for roughly 40% of global demand. HPQ holds exclusive North American commercialization rights for Novacium's silicon based battery technology under the HPQ ENDURA+ brand.UN 38.3 does not represent the end of every certification requirement. Tourillon confirmed that finished drone battery packs will require an additional certification process once pack designs are finalized. He described this as part of the normal commercialization process and said management does not currently expect it to prevent a first commercial order.WHAT YOU NEED TO KNOWSTRATEGIC IMPLICATIONS
There are more than 175 species of agave native to Mexico — so why is tequila made from just one? To answer that question, you have to understand centuries of tradition, industrialization, and the forces affecting Mexico's native spirits, and today, Pedro Jiménez, founder of Mezonte, joins me to unravel that history and explore one of the world's most fascinating spirits traditions.We Want to Hear from You!Have a topic, craft category, or craft company you'd like to see us cover? Email us at: info@blisterreview.com to share those or any other thoughts you have about CRAFTED.EPISODE SPONSORS: Momentous: livemomentous.com code: BlisterRELATED LINKS:MezonteViva Mezcal!Pare de SufrirRELATED LINKS: Get Yourself Covered: BLISTER+Order our 26/27 Winter Buyer's GuideEnter Our Free Weekly Gear GiveawaysTOPICS & TIMES:Pedro Jimenez's Background (2:01)Pare de Sufrir (14:24)Creating Mesonte (15:35)Mezcal As Culture (15:54)Mezcal vs. Tequila (22:24)Commercialization & Standardization (31:34)Exploring Agave Spirits (56:17)The Mezcal Production Process (48:26)Critique of Denomination of Origin (1:01:47)The Role of Transparency (1:12:27)Viva Mezcal (1:17:55)SEE OUR OTHER PODCASTS:The Blister VaultBlister CinematicBikes & Big IdeasGEAR:30Blister Podcast Hosted on Acast. See acast.com/privacy for more information.
What does it take to successfully commercialize medical technology in today's rapidly evolving healthcare landscape? In this episode, Mike Monovoukas, CEO and Co-Founder of AcuityMD, shares how a failed startup inspired him to build one of medtech's leading commercialization platforms. From leveraging AI and data to helping companies launch products more effectively, to raising an $80M Series C and building a mission-driven business, Mike offers valuable insights for medtech founders, innovators, and commercial leaders. Tune in to learn why commercialization starts long before product launch and how AI is changing the future of medtech. Mike Monovoukas LinkedInAcuityMD LinkedInAcuityMD WebsiteAcuityMD Press Release Biodesign Book Link Duane Mancini LinkedInProject Medtech WebsiteProject Medtech LinkedInThank you to our sponsors: Ward Law, Wheelhouse DMG, and JumpStart Inc.
Following Napoleon Bonaparte's 1798 campaign in Egypt, new possibilities of travel and improvements in printing technology saw an emergence of publishing ventures in France and Britain dedicated to the production of albums and travel accounts featuring images of Muslim Egypt and Islamic architecture and catering to a growing European fascination with the East. In her debut book, Visualizing Egypt: European Travel, Book Publishing, and the Commercialization of the Middle East in the Nineteenth Century (American University in Cairo Press, 2025) Paulina Banas analyzes the context and process of production of these highly illustrated publications, from their conceptualization to the finished product and its afterlife, from marketing to the sales of these books, and from circulation to their reception by nineteenth-century audiences. By tracing the long, arduous, and often risky publishing journeys of the makers of these books, including publishers, writers, and artists, such as the Frenchman Émile Prisse d'Avennes, Banas reveals a complex terrain of changing market demands, collaborations, and conflicting views, and the unsettled authorship of these works, prompting us to think more profoundly about artistic and intellectual exchange in the world of nineteenth-century Orientalist book production. Visualizing Egypt considers nineteenth-century book illustrations on Egypt and the “Orient” not merely as expressions of enduring ideology and colonial propaganda, but as representations shaped by the often-overlooked commercial exigencies of the growing publishing industry and the reckless competition within it. Paulina Banas is an Assistant Professor of Art History at The University of Alabama at Birmingham, where she teaches course on Islamic world arts, 19th century European visual culture, and cross-cultural encounters between Europe and the Middle East. Saman Nasser holds an M.A. in history from James Madison University, where he currently works as an educational staff. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network
Following Napoleon Bonaparte's 1798 campaign in Egypt, new possibilities of travel and improvements in printing technology saw an emergence of publishing ventures in France and Britain dedicated to the production of albums and travel accounts featuring images of Muslim Egypt and Islamic architecture and catering to a growing European fascination with the East. In her debut book, Visualizing Egypt: European Travel, Book Publishing, and the Commercialization of the Middle East in the Nineteenth Century (American University in Cairo Press, 2025) Paulina Banas analyzes the context and process of production of these highly illustrated publications, from their conceptualization to the finished product and its afterlife, from marketing to the sales of these books, and from circulation to their reception by nineteenth-century audiences. By tracing the long, arduous, and often risky publishing journeys of the makers of these books, including publishers, writers, and artists, such as the Frenchman Émile Prisse d'Avennes, Banas reveals a complex terrain of changing market demands, collaborations, and conflicting views, and the unsettled authorship of these works, prompting us to think more profoundly about artistic and intellectual exchange in the world of nineteenth-century Orientalist book production. Visualizing Egypt considers nineteenth-century book illustrations on Egypt and the “Orient” not merely as expressions of enduring ideology and colonial propaganda, but as representations shaped by the often-overlooked commercial exigencies of the growing publishing industry and the reckless competition within it. Paulina Banas is an Assistant Professor of Art History at The University of Alabama at Birmingham, where she teaches course on Islamic world arts, 19th century European visual culture, and cross-cultural encounters between Europe and the Middle East. Saman Nasser holds an M.A. in history from James Madison University, where he currently works as an educational staff. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/islamic-studies
Following Napoleon Bonaparte's 1798 campaign in Egypt, new possibilities of travel and improvements in printing technology saw an emergence of publishing ventures in France and Britain dedicated to the production of albums and travel accounts featuring images of Muslim Egypt and Islamic architecture and catering to a growing European fascination with the East. In her debut book, Visualizing Egypt: European Travel, Book Publishing, and the Commercialization of the Middle East in the Nineteenth Century (American University in Cairo Press, 2025) Paulina Banas analyzes the context and process of production of these highly illustrated publications, from their conceptualization to the finished product and its afterlife, from marketing to the sales of these books, and from circulation to their reception by nineteenth-century audiences. By tracing the long, arduous, and often risky publishing journeys of the makers of these books, including publishers, writers, and artists, such as the Frenchman Émile Prisse d'Avennes, Banas reveals a complex terrain of changing market demands, collaborations, and conflicting views, and the unsettled authorship of these works, prompting us to think more profoundly about artistic and intellectual exchange in the world of nineteenth-century Orientalist book production. Visualizing Egypt considers nineteenth-century book illustrations on Egypt and the “Orient” not merely as expressions of enduring ideology and colonial propaganda, but as representations shaped by the often-overlooked commercial exigencies of the growing publishing industry and the reckless competition within it. Paulina Banas is an Assistant Professor of Art History at The University of Alabama at Birmingham, where she teaches course on Islamic world arts, 19th century European visual culture, and cross-cultural encounters between Europe and the Middle East. Saman Nasser holds an M.A. in history from James Madison University, where he currently works as an educational staff. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/literary-studies
Following Napoleon Bonaparte's 1798 campaign in Egypt, new possibilities of travel and improvements in printing technology saw an emergence of publishing ventures in France and Britain dedicated to the production of albums and travel accounts featuring images of Muslim Egypt and Islamic architecture and catering to a growing European fascination with the East. In her debut book, Visualizing Egypt: European Travel, Book Publishing, and the Commercialization of the Middle East in the Nineteenth Century (American University in Cairo Press, 2025) Paulina Banas analyzes the context and process of production of these highly illustrated publications, from their conceptualization to the finished product and its afterlife, from marketing to the sales of these books, and from circulation to their reception by nineteenth-century audiences. By tracing the long, arduous, and often risky publishing journeys of the makers of these books, including publishers, writers, and artists, such as the Frenchman Émile Prisse d'Avennes, Banas reveals a complex terrain of changing market demands, collaborations, and conflicting views, and the unsettled authorship of these works, prompting us to think more profoundly about artistic and intellectual exchange in the world of nineteenth-century Orientalist book production. Visualizing Egypt considers nineteenth-century book illustrations on Egypt and the “Orient” not merely as expressions of enduring ideology and colonial propaganda, but as representations shaped by the often-overlooked commercial exigencies of the growing publishing industry and the reckless competition within it. Paulina Banas is an Assistant Professor of Art History at The University of Alabama at Birmingham, where she teaches course on Islamic world arts, 19th century European visual culture, and cross-cultural encounters between Europe and the Middle East. Saman Nasser holds an M.A. in history from James Madison University, where he currently works as an educational staff. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/middle-eastern-studies
Following Napoleon Bonaparte's 1798 campaign in Egypt, new possibilities of travel and improvements in printing technology saw an emergence of publishing ventures in France and Britain dedicated to the production of albums and travel accounts featuring images of Muslim Egypt and Islamic architecture and catering to a growing European fascination with the East. In her debut book, Visualizing Egypt: European Travel, Book Publishing, and the Commercialization of the Middle East in the Nineteenth Century (American University in Cairo Press, 2025) Paulina Banas analyzes the context and process of production of these highly illustrated publications, from their conceptualization to the finished product and its afterlife, from marketing to the sales of these books, and from circulation to their reception by nineteenth-century audiences. By tracing the long, arduous, and often risky publishing journeys of the makers of these books, including publishers, writers, and artists, such as the Frenchman Émile Prisse d'Avennes, Banas reveals a complex terrain of changing market demands, collaborations, and conflicting views, and the unsettled authorship of these works, prompting us to think more profoundly about artistic and intellectual exchange in the world of nineteenth-century Orientalist book production. Visualizing Egypt considers nineteenth-century book illustrations on Egypt and the “Orient” not merely as expressions of enduring ideology and colonial propaganda, but as representations shaped by the often-overlooked commercial exigencies of the growing publishing industry and the reckless competition within it. Paulina Banas is an Assistant Professor of Art History at The University of Alabama at Birmingham, where she teaches course on Islamic world arts, 19th century European visual culture, and cross-cultural encounters between Europe and the Middle East. Saman Nasser holds an M.A. in history from James Madison University, where he currently works as an educational staff. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/african-studies
Following Napoleon Bonaparte's 1798 campaign in Egypt, new possibilities of travel and improvements in printing technology saw an emergence of publishing ventures in France and Britain dedicated to the production of albums and travel accounts featuring images of Muslim Egypt and Islamic architecture and catering to a growing European fascination with the East. In her debut book, Visualizing Egypt: European Travel, Book Publishing, and the Commercialization of the Middle East in the Nineteenth Century (American University in Cairo Press, 2025) Paulina Banas analyzes the context and process of production of these highly illustrated publications, from their conceptualization to the finished product and its afterlife, from marketing to the sales of these books, and from circulation to their reception by nineteenth-century audiences. By tracing the long, arduous, and often risky publishing journeys of the makers of these books, including publishers, writers, and artists, such as the Frenchman Émile Prisse d'Avennes, Banas reveals a complex terrain of changing market demands, collaborations, and conflicting views, and the unsettled authorship of these works, prompting us to think more profoundly about artistic and intellectual exchange in the world of nineteenth-century Orientalist book production. Visualizing Egypt considers nineteenth-century book illustrations on Egypt and the “Orient” not merely as expressions of enduring ideology and colonial propaganda, but as representations shaped by the often-overlooked commercial exigencies of the growing publishing industry and the reckless competition within it. Paulina Banas is an Assistant Professor of Art History at The University of Alabama at Birmingham, where she teaches course on Islamic world arts, 19th century European visual culture, and cross-cultural encounters between Europe and the Middle East. Saman Nasser holds an M.A. in history from James Madison University, where he currently works as an educational staff. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/art
Following Napoleon Bonaparte's 1798 campaign in Egypt, new possibilities of travel and improvements in printing technology saw an emergence of publishing ventures in France and Britain dedicated to the production of albums and travel accounts featuring images of Muslim Egypt and Islamic architecture and catering to a growing European fascination with the East. In her debut book, Visualizing Egypt: European Travel, Book Publishing, and the Commercialization of the Middle East in the Nineteenth Century (American University in Cairo Press, 2025) Paulina Banas analyzes the context and process of production of these highly illustrated publications, from their conceptualization to the finished product and its afterlife, from marketing to the sales of these books, and from circulation to their reception by nineteenth-century audiences. By tracing the long, arduous, and often risky publishing journeys of the makers of these books, including publishers, writers, and artists, such as the Frenchman Émile Prisse d'Avennes, Banas reveals a complex terrain of changing market demands, collaborations, and conflicting views, and the unsettled authorship of these works, prompting us to think more profoundly about artistic and intellectual exchange in the world of nineteenth-century Orientalist book production. Visualizing Egypt considers nineteenth-century book illustrations on Egypt and the “Orient” not merely as expressions of enduring ideology and colonial propaganda, but as representations shaped by the often-overlooked commercial exigencies of the growing publishing industry and the reckless competition within it. Paulina Banas is an Assistant Professor of Art History at The University of Alabama at Birmingham, where she teaches course on Islamic world arts, 19th century European visual culture, and cross-cultural encounters between Europe and the Middle East. Saman Nasser holds an M.A. in history from James Madison University, where he currently works as an educational staff. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/communications
Sign up for PrizePicks with code: HMA and get $150 in lineups instantly when you play your first $5+ lineup! https://link.prizepicks.com/LME0/POWERHOUR #sponsored2026 LSU Tigers Read & Reaction Preview - https://read-and-reaction.sellfy.store/p/2026lsumag/ LSU Tigers Football & Lane Kiffin fans should join! - https://www.patreon.com/lsufootball Subscribe to Power Hour LSU! https://www.youtube.com/channel/UCz4trs8T2Bk9mSpcAakL3kw?sub_confirmation=1 Check out Power Hour SEC - https://www.youtube.com/@powerhoursec My New Orleans Saints show - https://bleav.com/shows/bleav-in-saints/ NEW “Thick Ness” SHIRT! - https://www.bonfire.com/34thick-ness34-t/ ________________________________________ PHL on Twitter: https://twitter.com/PowerHourLSU PHL on Instagram: https://www.instagram.com/powerhourlsu/ PHL on TikTok: https://www.tiktok.com/@powerhourlsu
Kaitlyn Tiffany tours modern-day Dallas, a strange mix of somber memorials and pop-culture commercialization of the assassination. Visitors can tour Ruth Paine's house or the rooming house where Oswald lived, which plays As the World Turns on a loop. While some local businesses sell "magic bullet coffee," the Sixth Floor Museum provides a staged look at the sniper's perch. Extensive archives of the critics' work are preserved at Hood College and the Mary Ferrell Foundation. (12)
All'inizio degli anni Duemila, il Senegal era un paese di secondo piano del calcio internazionale: non aveva mai ottenuto la qualificazione ai Mondiali e non era neppure mai arrivato in finale della Coppa d'Africa. Poi, all'improvviso, tutto è cambiato: merito di un giovane allenatore straniero e di una generazione di figli della diaspora.LE FONTI USATE PER QUESTO EPISODIO:- EDJOGO-OWONO Alberto, Indomable. Cuadernos del fútbol africano, Panenka- HAWKEY Ian, Feet of the Chameleon: The Story of African Football, Portico- M'BAYO Tamba E., Soccer in Senegal: National Identity, Commercialization, and Acquisition of Wealth, Palgrave MacMillan- MOGGIA Valerio, Il momento in cui ruggì il Senegal, Pallonate in FacciaLa musica è "Inspired" di Kevin MacLeod [incompetech.com] Licenza C.C. by 4.0Potete seguire Pallonate in Faccia ai seguenti link:https://pallonateinfaccia.com/https://www.facebook.com/pallonateinfacciabloghttps://twitter.com/pallonatefacciahttps://www.instagram.com/pallonateinfaccia/Per contattarmi: pallonateinfaccia@gmail.comIscrivetevi alla newsletter THE BEAUTIFUL SHAME!COME SOSTENERE PALLONATE IN FACCIA
This week we had the exciting opportunity to travel to Lake Forest, California, to tour TAE Technologies' facilities and spend time with the company's CEO, Dr. Michl Binderbauer. Founded in 1998, TAE has spent nearly three decades pursuing one of the energy industry's most ambitious goals: commercializing a safe, sustainable, and economically viable source of fusion energy. With renewed momentum in the fusion industry, we thought it was the perfect time to visit TAE and better understand why many believe fusion's moment may finally be approaching. Our visit also marks the beginning of a California COBT series, where over the coming weeks, we'll highlight some of the state's innovative companies, technologies, and leaders. We will also touch on a challenge or two the state is facing. Stay tuned! In our discussion, Michl explains why he believes fusion has reached a true inflection point after nearly three decades of scientific and engineering progress. He outlines why TAE was founded with the “end in mind,” deliberately choosing the more technically challenging hydrogen-boron fuel cycle because it offered the best path to a commercially viable power plant rather than simply proving the science. We explore how advances in AI, machine learning, advanced computing, and materials science have accelerated development, why TAE believes commercial fusion is now measured in years rather than decades, and how the company is preparing to build its first demonstration power plant. We discuss TAE's innovative approach to commercializing technologies developed along the way, including its advanced power management platform that is finding applications in AI data centers, industrial facilities, and grid modernization. Michl shares his vision for fusion's role in delivering abundant, reliable energy to meet the world's rapidly growing electricity demand, the importance of recent U.S. regulatory reforms, the race with China to commercialize fusion, workforce and supply chain challenges, and why he believes fusion has become not only an energy opportunity, but also an economic and national security imperative. We look at what the next five years could look like for TAE, why hyperscalers, industrial customers, and the Department of War may become some of fusion's earliest adopters before widespread utility deployment, the company's long-term vision for a more distributed electric grid, and much more. It was a fascinating and wide-ranging discussion, and we greatly appreciate Michl for sharing his time and insights. To start the show, Mike Bradley noted that markets have been volatile this week. He highlighted that the cooler-than-expected CPI report sparked a rally in Treasuries, driving the 10-year yield down from roughly 4.65% to 4.55%, and said Wednesday's PPI report will be another important data point for the Fed. U.S. equities also moved higher, with the S&P 500 gaining approximately 0.5% on the back of the CPI report and strong bank earnings, while the Dow lagged following a sharp selloff in IBM shares after disappointing quarterly results. In commodities, Brent and WTI crude prices climbed roughly $8-$9/bbl this week following the collapse of the Iran-U.S. ceasefire and renewed disruptions through the Strait of Hormuz. He emphasized that today's challenge is less a global crude supply issue than a global refining problem, citing tight refined product inventories and the loss of roughly 1.5 million bpd of Russian refining capacity following Ukrainian attacks. He also highlighted that European natural gas prices have surged from approximately $16/MMBtu to $19/MMBtu as storage levels remain 20%-25% below seasonal norms and buyers compete for LNG cargoes. Mike noted that Energy is the best-performing S&P 500 sector this week, up approximately 3%, as investors turn their attention to second-quarter oilfield services earnings. He also highlighted the newly announced strategic alliance between SLB and Liberty Energy focused on data center infrastructure and power solutions, noting that similar partnerships are likely to become increasingly common across the energy sector.
Guest: In this special episode recorded live in Montréal, Canada at ISSCR 2026, Dr. Michael May, President and CEO of the Centre for Commercialization of Regenerative Medicine (CCRM), and Dr. Janet Rothberg, Senior Director of Process and Analytical Development at CCRM, explore how stem cell discoveries can be translated into commercially viable therapies through scalable manufacturing, company creation, investment, automation, and artificial intelligence. They emphasize the importance of considering manufacturing, quality control, market selection, reimbursement, and the evolving standard of care much earlier in the development process. They also share their vision for a future in which robust bioprocessing, better use of data, and improved regulatory and reimbursement models make iPSC-derived therapies more affordable and widely accessible. Photo Reference: Courtesy of Drs. Michael May and Janet Rothberg Subscribe to our newsletter! Never miss updates about new episodes. Subscribe
Through the commercialization of life-preserving technologies, NASA remains at the heart of health solutions.
The tile game Mah-Jongg has become incredibly popular among American women, spawning clubs, tournaments, and brands, and some have raised concerns about the Americanization and commercialization of the game. Atlantic staff writer Ashley Parker discusses mah-jongg's recent rise in popularity, as well as her own ‘descent into Mah-Jongg', which she detailed in a recent article. Photo by Eric Lee/For The Washington Post via Getty Images: People play "wash" Mahjong tiles during "Mahjong Night" at the Martin Luther King Jr. Library in Washington, D.C. on Tuesday, July 22, 2025. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
This week on Cooking Issues, Dave and the crew are joined by Alex Hawk, Manager of Culinary Innovation at Burger King, and Zach Young, Director of Culinary and Commercialization at Burger King, for a rare look inside the food science, logistics, and product development behind one of the largest restaurant systems in the world.They get into what it actually takes to create food for millions of people: bakery supply chains, fresh bread logistics, Whopper improvements, tomato specs, lettuce formats, clean-label constraints, regional menu development, and the challenge of making recipes work across thousands of restaurants and multiple generations of equipment.The conversation also covers home frying versus commercial frying, fryer oil, Popeyes chicken, Burger King's relationship to Puerto Rico and the Whopper Jr., artificial sweeteners, frozen carbonated beverages, CVAP ovens, water fryers, potato freezers measured in hundreds of millions of pounds, and why even a seemingly simple menu change can become a massive operational question.Plus: Diet Coke loyalty, green ketchup, edible Tide Pods that mercifully never happened, the original chicken sandwich, secret-menu chaos, and the realities of innovating inside a global fast-food system. Hosted on Acast. See acast.com/privacy for more information.
Jann, Caitlin & Sarah catch up about Caitlin's search for a new home, summer activities in Iceland, and the excitement surrounding the World Cup. Caitlin fills us in about the ranch dressing craze among European soccer fans, and the commercialization of the fan detested hydration breaks. Jann also invites app developer Travis Weniger to discuss his app, Memento Mori. It predicts life expectancy based on various health metrics while blending the philosophies of stoicism and longevity. The conversation delves into the importance of recognizing life's finiteness. Travis shares insights on how discussions about death can lead to a more fulfilling life, and the importance of balancing enjoyment with health-conscious choices. The conversation explores mortality, and the importance of living meaningfully. More About Travis Weninger: Travis Weninger is an independent product designer, developer, and writer based in Toronto. His work explores the intersection of technology, philosophy, and intentional living. After spending nearly a decade working in the tech industry, he left the corporate world to pursue his own path and founded socialdotgood, an independent software company focused on building thoughtful consumer products. Through socialdotgood, Travis has launched six apps, with Memento Mori being his most ambitious project to date. Inspired by Stoic philosophy and the ancient practice of reflecting on mortality, the app is a meditation on one's mortality paired with contemporary research on longevity. Resources & Links: YearsLeft.io – Travis Weniger's mortality prediction app https://www.blogto.com/tech/2026/02/toronto-app-raising-eyebrows/ https://www.blogto.com/tech/2026/04/toronto-app-predict-when-die/ #ASKJANN - want some life advice from Jann? Send in a story with a DM or on our website. Leave us a voicenote! www.jannardenpod.com/voicemail/ Get access to bonus content and more on Patreon: www.patreon.com/JannArdenPod Connect with us: www.jannardenpod.com www.instagram.com/jannardenpod www.facebook.com/jannardenpod Chapters: (00:00) Introduction and Catch-Up (03:04) Moving Challenges and Life Updates (06:00) Summer in Iceland and Family Activities (08:51) World Cup Excitement and Cultural Discoveries (12:02) Hydration Breaks and Commercialization in Sports (14:58) Social Dynamics During the World Cup (17:49) Legacy and the Concept of Time (22:02) Introducing Travis and the Memento Mori App (25:50) The Intimacy Tracking App (28:15) Philosophical Insights on Life and Death (32:03) Mitigating factors that impact longevity (36:17) Death app demo in Patreon Learn more about your ad choices. Visit megaphone.fm/adchoices
Welcome to another episode of HALO Talks! Today, Pete Moore is joined by Dr. Joel Seedman and Sal LoDuca for a discussion on advanced human performance and an innovative strength training methodology known as offset loading. Sal shares the origins of their company and his quest to enhance the nervous system of athletes through contralateral training and randomized exercise, which led him to discover and collaborate with Dr. Seedman, often referred to as "The father of offset loading." Together, they dive into the science and practice behind offset loading, its demonstrated benefits in boosting strength and hypertrophy, and its potential to revolutionize fitness across diverse populations, from elite athletes to those with neuromotor conditions. The conversation also explores upcoming AI-powered equipment, patent approvals, published research, and how their approach challenges conventional wisdom in the strength and conditioning world. Tune in for insights on how this technique not only exposes and corrects physical asymmetries, but also enhances cognitive effort and neurological adaptation, setting a new standard for functional fitness. On the viral potential of offset leading, LoDuca states, "We have so many verticals that we can now attack. We can attack general fitness, we can attack athletes, we can attack neuromotor conditions like early stage Parkinson's or MS. We can attack military training, and we can attack other potential cognitive diseases as well." Key themes discussed Origins of offset loading and company origin Neurological and physiological benefits of offset loading Offset loading's role in injury prevention and performance Commercialization and patenting of new fitness equipment Application of AI and metrics for personalized training Offset loading for athletes, general population, and neurological conditions Need for certification and industry education on offset methods A Few Key Takeaways 1. Origins and Concept of Offset Loading: Offset loading originated from an exploration into methods that would expand the nervous system of athletes, particularly through randomization and contralateral training. This technique, which Dr. Seedman has practiced and refined for over a decade, involves using different weights on each side of the body to challenge both sides of the brain and improve performance and resilience in athletes 00:27. 2. Scientifically Proven Benefits: A study on offset loading in the bench press demonstrated its effectiveness, increasing strength by 36% and muscle size (hypertrophy) by 44% compared to traditional training methods. This provided measurable proof of offset loading's value beyond anecdotal experience 05:11. 3. Technology and AI Integration: Plans are underway to commercialize offset loading using patented machines with independent electromagnetic resistance motors and artificial intelligence. These machines will measure user asymmetry and automatically adjust resistance, aiming to both expose and correct muscular imbalances efficiently and safely 05:32. 4. Neurological Advantages: Recent research using EEG caps found that offset loading enhances connectivity between the sensory, motor, and cognitive brain areas, requiring increased cognitive effort and expanding the nervous system more than traditional, repetitive weightlifting 10:03. 5. Wide-Ranging Applications and Market Approach: Offset loading is not only beneficial for elite athletes but also has applications for general fitness, rehabilitation, neuromotor diseases (like early-stage Parkinson's), and military training. The team is developing both certification protocols for trainers and the specialized equipment, emphasizing the importance of education for widespread adoption in the fitness industry 07:35, 19:42. Resources: Dr. Joel Seedman: https://www.advancedhumanperformance.com Sal LoDuca: https://www.linkedin.com/in/salvatore-loduca-44394922 Integrity Square: https://www.integritysq.com Prospect Wizard: https://www.theprospectwizard.com Promotion Vault: https://www.promotionvault.com HigherDose: https://www.higherdose.com
Brands like AP, Vacheron, IWC, and many others have inventories and histories that create a mountain of little-known watches whose pedigree, watchmaking, and design are just as standout as their more well-known counterparts. In this episode, Armand and special guest CQ pull from The 1916 Company vault to find these hidden gem examples. From discontinued models like the Audemars Piguet Millenary to off-the-beaten-path examples of well known lines like the IWC Ingenieur and Vacheron Constantin Overseas, you'll want to see what the guys pulled for this one! Please Subscribe: https://www.youtube.com/@1916company/?sub_confirmation=1 Download the app: https://onelink.to/8u2bgh Buy Watches Here: https://www.the1916company.com View hands-on luxury watch reviews on The 1916 Company Watch Reviews: https://www.youtube.com/@the1916companywatchreviews/?sub_confirmation=1 Instagram: https://www.instagram.com/the1916company 0:00 Introduction 1:18 Audemars Piguet: Current Collection and the Millenary 7:32 Royal Oak Offshore 10:56 The Commercialization vs. Craft of Watchmaking 15:11 Vacheron Constantin Skeleton Patrimony 18:30 The Challenges of Servicing Watch Movements 24:47 JLC Master Compressor World Time 28:16 IWC Big Pilot "Muhammad Ali" 31:40 IWC Ingenieur Chronograph 33:40 Vacheron Constantin Overseas 35:30 The Making of a Standout Sports Watch 39:25 Closing Thoughts
Commercialization is becoming increasingly connected, complex and accountable. In this MM+M Agency 100 conversation, BGBx CEO David Coman discusses what has changed, where organizations struggle and why success increasingly depends on connecting strategy, evidence, access, analytics and execution. Check us out at: mmm-online.com Follow us: YouTube: @MMM-online TikTok: @MMMnews Instagram: @MMMnewsonline Twitter/X: @MMMnews LinkedIn: MM+M To read more of the most timely, balanced and original reporting in medical marketing, subscribe here. Music: “Deep Reflection” by DP and Triple Scoop Music. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
In this Omni Talk Retail interview, recorded live from the Global DIY Summit 2026 in Amsterdam, Chris Walton talks with Raha Been, Senior Vice President of Research & Development and Commercialization, Consumer Business at 3M, about innovation, consumer behavior, and how one of the world's most recognizable brands is adapting to a rapidly changing market. Raha shares her unique journey from cancer research and molecular biology to leading innovation for 3M's Consumer Business, and explains how the company is accelerating its innovation pipeline while maintaining the rigor and accountability that have defined 3M for more than 120 years. She discusses how 3M evaluates new product opportunities, the role partnerships play in bringing innovation to market, and why successful innovation requires balancing speed, creativity, and disciplined execution. Raha also explores how younger consumers are reshaping product development. As Millennials and Gen Z gain purchasing power, expectations are shifting beyond functionality toward personalization, self-expression, and experience. Using Scotch-Brite as an example, she explains how even everyday household products are evolving to reflect changing consumer preferences and lifestyles. Key Topics Covered: • Raha Been's journey from molecular biology and cancer research to retail innovation • How 3M is accelerating innovation under CEO Bill Brown • Balancing speed, agility, and accountability in product development • The role of 3M's stage-gate innovation process • Organic innovation versus partnerships and external collaboration • How 3M evaluates new product opportunities and risk • Why Millennials and Gen Z are reshaping consumer expectations • The shift from utility-driven purchases to experience-driven purchases • How Scotch-Brite products are evolving for a new generation of consumers • Why innovation requires both technology expertise and customer understanding Thank you to Vusion for supporting Omni Talk Retail's live coverage from the Global DIY Summit 2026 in Amsterdam.
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In this episode, Dr. Malcolm Townes breaks down how WashU is building a more execution-focused commercialization engine through its Gap Fund, designed to advance non-drug, non-therapeutic technologies by funding the technology (not startups) to avoid conflicts and drive sharper development decisions. He shares why hands-on, milestone-based funding and rigorous customer discovery are essential to uncovering “unknown unknowns,” preventing expert blindness, and aligning products with real clinical workflows. The conversation also explores how WashU leverages EIRs and Venture Fellows to add commercialization horsepower, why “coachability” is the strongest predictor of success, and what innovators most often miss: FDA clearance isn't enough—market access and reimbursement require different proof, data, and strategy.Dr. Malcolm Townes LinkedInWashington University in St. Louis Gap Fund WebsiteDuane Mancini LinkedInProject Medtech WebsiteProject Medtech LinkedInThank you to our sponsors: Ward Law and JumpStart Inc.
Applications are open through July 24 for entrepreneurs looking to turn dairy-based ideas into successful products.
Silicon solar panels have led the market for decades but will soon hit a ceiling around 25% efficiency. Perovskite, a frontier material once dismissed for degrading too fast, is now being called the holy grail of solar. Saritha Peruri, VP of Commercialization at Tandem PV, is bringing it to market. The company stacks its proprietary perovskite on top of silicon, capturing a wider spectrum of light and pushing efficiency past 30%, a major jump over conventional solar. And because it builds on the silicon PV infrastructure that already exists, the path to scale stays simple. Getting there wasn't easy. After a long Series A, Tandem PV pulled off something rare in deep-tech hardware: 100% equipment financing for its 40-megawatt demonstration factory. It's now shipping quarter-sized modules to utility-scale customers who want U.S.-made panels for supply chain certainty and the domestic content kicker. It's potentially a bridge to a post-ITC world that cuts land and labor costs because each installation needs far fewer modules. In this episode, host Lara Pierpoint talks with Saritha about reaching high durability and the challenges of financing deep-tech hardware. Credits: Hosted by Lara Pierpoint. Produced and edited by Ross Kenyon and Anne Bailey. Technical direction by Sean Marquand. Stephen Lacey is our executive editor. The Green Blueprint is a co-production of Latitude Media and Trellis Climate. Subscribe on Apple, Spotify, or anywhere you get podcasts. For more reporting on the companies featured in this show, subscribe to Latitude Media's newsletter.
This week on Autonomy Signals presented by KPMG Grayson Brulte and Rob Grant discuss Figure AI's first commercial humanoid deployment with Catalyst Brands, Stellantis L2++ partnership with Wayve, and Starship Technologies surpassing 10 million autonomous deliveries.Figure AI recently signed a commercial agreement with Catalyst Brands to deploy humanoid robots at a JCPenney distribution center in Reno, Nevada, integrating Figure's humanoids into Catalyst's Joey Pouch sorting system.As new management at Stellantis looks to turn around the global OEM, the company is pursuing a partnership over build strategy to accelerate their expansion into the L2++ market, with a targeted launch beginning with the Jeep Grand Cherokee.Then there is Starship Technologies, which recently surpassed 10 million autonomous deliveries with 3,000 robots operating across more than 300 locations in eight countries. The company says autonomous delivery is already $3 to $4 cheaper than rider-based models, with a long-term target of $1 per drop, though sustained profitability will require lowering the teleoperator intervention rate to near zero while navigating city-by-city municipal regulation.Episode Chapters00:00 Signal 1: Figure AI Signs Commercial Agreement with Catalyst Brands18:10 Signal 2: Stellantis Partners with Wayve to Deploy L2++ in U.S.41:06 Signal 3: Starship Technologies Surpasses 10 Million Autonomous Deliveries59:13 AUTNMY AIAutonomy Signals is presented by KPMG.--------About The Road to AutonomyThe Road to Autonomy is the leading applied intelligence platform covering the convergence of automation, autonomy, and the Autonomy Economy.™.Through our podcasts, newsletter, and proprietary market intelligence, we set the narrative for institutional investors, industry executives, and policymakers navigating the convergence of automation, autonomy, and economic growth.Join institutional investors and industry leaders who read This Week in The Autonomy Economy every Sunday. Each edition delivers exclusive insight and commentary on the autonomy economy, helping you stay ahead of what's next.Subscribe today: https://www.roadtoautonomy.com/ae/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
What actually creates innovation? Is it technology, intelligence, funding… or something much deeper? In this episode of Success Leaves Clues, Robin Bailey and Al McDonald sit down with Hugh Chow, CEO at ventureLAB, inventor, entrepreneur, investor, and global innovation leader, to explore the mindset behind breakthrough leadership, meaningful innovation, and building companies that create lasting impact.With more than 30 years of experience across semiconductors, startups, venture capital, sustainability, and global technology, Hugh shares the deeply personal journey that shaped his perspective on leadership, opportunity, and resilience. From immigrating to North America to helping scale technology companies with hundreds of patents and hundreds of millions in revenue, Hugh unpacks what it really takes to build something meaningful in a rapidly changing world.This conversation explores the future of Canadian innovation, why founders need to think globally from day one, and how true innovation comes from challenging the status quo rather than accepting it. Hugh also shares why he believes leadership is about creating opportunities for others, lifting people up, and planting seeds for future generations to grow.Throughout the episode, Hugh offers powerful insights on entrepreneurship, commercialization, AI, hardtech, startup ecosystems, mentorship, and the lessons he learned from his parents that continue to guide his leadership today.If you've ever wondered what separates visionary leaders from everyone else, or how innovation can become a force for long-term impact, this episode delivers a masterclass in leadership, humility, and purpose-driven growth.You'll hear about:Why innovation starts with challenging the status quo The leadership philosophy behind building win-win relationships How one phone call changed the trajectory of Hugh's career Why great leaders recognize talent before people see it in themselves The difference between taking risks and creating opportunity Why Canadian founders need to think globally from the beginning The commercialization gap holding Canadian innovation back What makes Canada one of the strongest innovation ecosystems in the world The future of AI, hardtech, and medical technology startups Why learning matters more than avoiding failure The importance of sustainability and lifting others up How Hugh's parents shaped his approach to leadership and resilienceWe talk about:00:00 Introduction to Hugh Chow and ventureLAB02:00 Seeing potential in people before they see it themselves05:00 Why leadership is about creating win-win opportunities08:30 The career moments that shaped Hugh's innovation mindset10:00 Moving to North America and starting in semiconductors13:00 Building a global technology company from Canada15:00 What innovation actually means in today's world17:00 Why innovation requires challenging the status quo19:00 Leadership, sustainability, and creating long-term impact21:00 Canada's strengths in innovation and AI23:00 Why Canadian companies must think globally25:00 Commercialization challenges in Canada28:00 The future of hardtech, AI, and medical technology31:00 What founders often misunderstand about success34:00 Supporting startups through uncertainty and change36:00 The question every leader should ask themselves38:00 Hugh's parents, resilience, and the lessons that shaped his life42:00 Why opportunity should be passed on to future generationsConnect with HughLinkedIn: https://www.linkedin.com/in/hugh-chow-445b332/ Website: https://www.venturelab.ca/ Connect with UsLinkedIn: Robin Bailey and Al McDonald Website: Aria Benefits and Life & Legacy Advisory Group
Stephen Grootes speaks to Francois Rossouw, CEO of Southern African Agri Initiative, about the Pretoria High Court’s landmark ruling allowing farmers and livestock owners to privately procure and administer Foot-and-Mouth Disease vaccines without State veterinary involvement In other interviews, Kelvin Watt, Chairman of Nielsen Sports Africa talks about the battle for South African sports audiences between soccer and rugby, and which codes are attracting the biggest commercial opportunities, the growing sponsorship value and what South Africans’ deep emotional connection to sport reveals about consumer behaviour, brand loyalty and the future of sports entertainment. The Money Show is a podcast hosted by well-known journalist and radio presenter, Stephen Grootes. He explores the latest economic trends, business developments, investment opportunities, and personal finance strategies. Each episode features engaging conversations with top newsmakers, industry experts, financial advisors, entrepreneurs, and politicians, offering you thought-provoking insights to navigate the ever-changing financial landscape. Thank you for listening to a podcast from The Money Show Listen live Primedia+ weekdays from 18:00 and 20:00 (SA Time) to The Money Show with Stephen Grootes broadcast on 702 https://buff.ly/gk3y0Kj and CapeTalk https://buff.ly/NnFM3Nk For more from the show, go to https://buff.ly/7QpH0jY or find all the catch-up podcasts here https://buff.ly/PlhvUVe Subscribe to The Money Show Daily Newsletter and the Weekly Business Wrap here https://buff.ly/v5mfetc The Money Show is brought to you by Absa Follow us on social media 702 on Facebook: https://www.facebook.com/TalkRadio702 702 on TikTok: https://www.tiktok.com/@talkradio702 702 on Instagram: https://www.instagram.com/talkradio702/ 702 on X: https://x.com/CapeTalk 702 on YouTube: https://www.youtube.com/@radio702 CapeTalk on Facebook: https://www.facebook.com/CapeTalk CapeTalk on TikTok: https://www.tiktok.com/@capetalk CapeTalk on Instagram: https://www.instagram.com/ CapeTalk on X: https://x.com/Radio702 CapeTalk on YouTube: https://www.youtube.com/@CapeTalk567 See omnystudio.com/listener for privacy information.
Moore's Law has been a cornerstone of the rapid advancement of digital technology over the past decades, although it is now confronting physical limits and diminishing economic returns.过去几十年,摩尔定律一直是数字技术快速进步的基石,尽管如今它正面临物理极限和边际收益递减的挑战。For an industry conditioned to equate progress with nanometers, the Tau Scaling Law disclosed by Huawei on Monday is a challenge to the organizing logic of the semiconductor ecosystem.对于一个习惯于用纳米衡量进步的行业而言,华为5月25日公布的“τ scaling law”(陶缩放定律)无疑是对半导体生态系统运行逻辑的一次挑战。Instead of continuing the increasingly expensive race to shrink transistors, Tau Scaling proposes that future chip performance gains can come from compressing the signal propagation time through architectural and timing innovations. Huawei has set a target of reaching a chip density equivalent to 1.4 nanometers by 2031.陶缩放定律提出,摒弃代价日益高昂的晶体管微缩竞赛,转而通过架构与时序创新压缩信号传播时间,驱动未来芯片性能提升。华为已设定目标,到2031年实现相当于1.4纳米制程的芯片密度。Washington's export restrictions have attempted to cut China off from advanced lithography equipment, leading-edge foundries and portions of the global event-driven architecture software stack. Such measures were designed to slow China's progress in advanced semiconductors.美国的出口限制试图将中国排除在先进光刻设备、前沿代工厂以及部分全球事件驱动架构软件栈之外。这些措施旨在减缓中国在先进半导体领域的进步。That is where Tau Scaling enters the picture. Instead of shrinking transistor dimensions from 3 nm to 2 nm and beyond, Huawei is extracting more performance from mature process nodes such as 5 nm and 7 nm by means of architectural optimization, timing compression, logic folding and system-level coordination.这正是陶缩放定律发挥作用的地方。华为不再追求从3纳米到2纳米及更小尺寸的晶体管微缩,而是通过架构优化、时序压缩、逻辑折叠和系统级协调等手段,从5纳米、7纳米等成熟工艺节点中挖掘更多性能。Much of the underlying research — including asynchronous computing concepts, wave pipelining, and timing optimization techniques — can be traced back decades. What Huawei has done, under conditions where the traditional scaling route became inaccessible, is to revisit those ideas, combine them, enhance them and industrialize them.许多基础性研究,包括异步计算概念、波流水线技术和时序优化技术等都可以追溯到几十年前。华为所做的,是在传统微缩路径受阻的情况下,重新审视这些想法,将它们加以融合、改进并产业化。In that sense, the emergence of Tau Scaling reflects a broader historical pattern in technology. Constraints often redirect innovation rather than stop it. So, if chip performance can be improved through architecture rather than lithography alone, then the balance of competition changes. The key question becomes not simply who owns the most advanced EUV machines, but who can design the most efficient systems using available manufacturing capabilities.从这个意义上说,陶缩放定律揭示了技术发展的一条普遍规律:限制往往促使创新转向,而非将其扼杀。若芯片性能可借架构而非单纯依赖光刻技术提升,竞争的格局便将随之改变。关键问题不再是“谁拥有最先进的极紫外光刻机”,而是“谁能利用现有制造能力设计出最高效的系统”。It would be premature, though, to declare that the arrival of Tau Scaling heralds the post-Moore era. Semiconductor history is filled with elegant concepts that struggled once they encountered manufacturing economics, ecosystem inertia, or commercial realities. Huawei's proposal faces several important ceilings.不过,现在就说陶缩放定律预示后摩尔时代已经开启,未免为时过早。半导体发展史上不乏精妙构想,但一旦遭遇制造经济学、生态系统惯性或商业现实,便会步履维艰。华为的方案目前仍面临若干关键瓶颈。Architecture cannot completely replace physics. Timing optimization can reduce inefficiencies, but signals still obey physical propagation limits. As chips become larger and workloads more complex, interconnect delays and synchronization overhead remain major bottlenecks.架构终究无法替代物理规律。时序优化虽能减少低效,信号却始终受制于物理传播的极限。随着芯片尺寸不断增大、工作负载日趋复杂,互连延迟与同步开销仍是绕不开的主要瓶颈。Logic folding and time-domain optimization introduce their own complexity penalties. The more aggressively a design compresses timing, the harder verification, debugging and manufacturing become. Commercialization will determine whether Tau Scaling becomes an industry framework. For Huawei's approach to become influential, other companies must adopt it, customers must validate it and developers must build around it. That process will take years, not conference announcements.逻辑折叠与时域优化本身也需付出复杂性代价。设计越激进地压缩时序,验证、调试与制造的难度便越大。陶缩放定律能否成为行业框架,最终取决于商业化落地。华为的方案要产生影响力,必须获得其他公司的采纳、客户的验证以及开发者的生态共建。这需要数年之功,而非一场发布会所能成就。Even so, the broader lesson already stands. The semiconductor industry is entering a phase where innovation no longer relies exclusively on brute-force scaling and trillion-dollar capital expenditures. Architectural intelligence, software-hardware codesign, advanced packaging and system optimization are becoming increasingly important.即便如此,一个更宏观的启示已然显现:半导体行业正步入新阶段——创新不再单纯依赖蛮力微缩与万亿美元级的资本投入。架构智能、软硬件协同设计、先进封装与系统优化,正变得日益关键。For China, that shift creates both an opportunity and a responsibility. The country still faces major gaps in lithography, materials, EDA tools and manufacturing equipment. But Tau Scaling demonstrates something equally important: when external pressure blocks one route, researchers will look for alternative routes and solutions can emerge through persistence, engineering discipline and targeted input.对中国而言,这一转变既是机遇,也是责任。尽管在光刻、材料、EDA工具及制造设备上差距显著,但陶缩放定律揭示了一个重要道理:外部压力堵住一条路,科研人员就会开辟另一条路。凭借坚韧、工程严谨和精准投入,解决方案终将破土而出。The semiconductor race is no longer just about making things smaller. Increasingly, it is about making systems smarter. The challenge now is for more Chinese companies and engineers to push beyond incremental imitation and focus on resolving genuine choke-point technologies with the tools they already possess.半导体竞赛,已从单纯追求“更小”转向致力实现“更智能”。当务之急,是更多中国企业与工程师超越渐进式模仿,立足现有工具,攻克真正的“卡脖子”技术。Moore's Law /mʊəz lɔː/摩尔定律diminishing economic returns /dɪˈmɪnɪʃɪŋ ˌiːkəˈnɒmɪk rɪˈtɜːnz/边际收益递减conditioned to /kənˈdɪʃənd tuː/习惯于Tau Scaling Law /taʊ ˈskeɪlɪŋ lɔː/ τ缩放定律(陶缩放定律)semiconductor ecosystem /ˌsemikənˈdʌktər ˈiːkəʊsɪstəm/半导体生态系统shrink transistors /ʃrɪŋk trænˈzɪstəz/微缩晶体管advanced lithography equipment /ədˈvɑːnst lɪˈθɒɡrəfi ɪˈkwɪpmənt/先进光刻设备leading-edge foundries /ˈliːdɪŋ edʒ ˈfaʊndriz/前沿代工厂event-driven architecture /ɪˈvent ˈdrɪvən ˈɑːkɪtektʃə/事件驱动架构asynchronous computing /eɪˈsɪŋkrənəs kəmˈpjuːtɪŋ/异步计算wave pipelining /weɪv ˈpaɪplaɪnɪŋ/波流水线EUV machines /ˌiː juː ˈviː məˈʃiːnz/极紫外光刻机post-Moore era /pəʊst mʊə ˈɪərə/后摩尔时代manufacturing economics /ˌmænjʊˈfæktʃərɪŋ ˌiːkəˈnɒmɪks/制造经济学ecosystem inertia /ˈiːkəʊsɪstəm ɪˈnɜːʃə/生态系统惯性software-hardware codesign /ˈsɒftweə ˈhɑːdweə ˌkəʊdɪˈzaɪn/软硬件协同设计advanced packaging /ədˈvɑːnst ˈpækɪdʒɪŋ/先进封装system optimization /ˈsɪstəm ˌɒptɪmaɪˈzeɪʃən/系统优化lithography /lɪˈθɒɡrəfi/光刻EDA tools /ˌiː diː ˈeɪ tuːlz/电子设计自动化工具
Stephen Grootes speaks to Kelvin Watt, chairperson of Nielsen Sports Africa, about the battle for South African sports audiences between soccer and rugby, and which codes are attracting the biggest commercial opportunities. They also look at the growing sponsorship value and what South Africans’ deep emotional connection to sport reveals about consumer behaviour, brand loyalty and the future of sports entertainment. The Money Show is a podcast hosted by well-known journalist and radio presenter, Stephen Grootes. He explores the latest economic trends, business developments, investment opportunities, and personal finance strategies. Each episode features engaging conversations with top newsmakers, industry experts, financial advisors, entrepreneurs, and politicians, offering you thought-provoking insights to navigate the ever-changing financial landscape. Thank you for listening to a podcast from The Money Show Listen live Primedia+ weekdays from 18:00 and 20:00 (SA Time) to The Money Show with Stephen Grootes broadcast on 702 https://buff.ly/gk3y0Kj and CapeTalk https://buff.ly/NnFM3Nk For more from the show, go to https://buff.ly/7QpH0jY or find all the catch-up podcasts here https://buff.ly/PlhvUVe Subscribe to The Money Show Daily Newsletter and the Weekly Business Wrap here https://buff.ly/v5mfetc The Money Show is brought to you by Absa Follow us on social media 702 on Facebook: https://www.facebook.com/TalkRadio702 702 on TikTok: https://www.tiktok.com/@talkradio702 702 on Instagram: https://www.instagram.com/talkradio702/ 702 on X: https://x.com/CapeTalk 702 on YouTube: https://www.youtube.com/@radio702 CapeTalk on Facebook: https://www.facebook.com/CapeTalk CapeTalk on TikTok: https://www.tiktok.com/@capetalk CapeTalk on Instagram: https://www.instagram.com/ CapeTalk on X: https://x.com/Radio702 CapeTalk on YouTube: https://www.youtube.com/@CapeTalk567 See omnystudio.com/listener for privacy information.
Stay informed on current events, visit www.NaturalNews.com - Memorial Day Message and Introduction to Energy Technology (0:02) - Impact of the War in Iran on Energy Technology (3:59) - Commercialization and Future of LENR Technology (8:00) - Challenges and Opportunities in Energy Transition (9:11) - Memorial Day Sale and Store Updates (9:34) - Translation Projects and Future Plans (12:26) - Impact of the War in Iran on Global Energy Supply (14:56) - Advancements in Battery Technology (36:37) - Challenges in Data Center Development (56:16) - Potential for Decentralized Power Production (1:17:59) - X AI's Tactics and Community Pushback (1:18:16) - Health Impact of Gas Turbines (1:20:33) - Community Action and Activist Movements (1:22:41) - Technological Overkill and Data Center Viability (1:29:53) - China's Role in Data Center Scaling (1:33:58) - Digital ID and Surveillance Infrastructure (1:37:57) - The Spiritual and Practical Implications of Data Centers (1:46:01) - The Role of Decentralized Technology (1:53:12) - The Impact of Social Media and Addictions (2:06:28) - The Importance of Natural Dopamine Support (2:11:30) - Impact of Media and Pharma on Public Perception (2:33:51) - Awareness and Establishment Resistance (2:36:03) - Historical and Current Pharma Scandals (2:39:20) - Natural Solutions and Superfoods (2:41:33) - Impact of Toxic Ingredients and Seed Oils (2:45:28) - Glyphosate and Corporate Influence (2:53:25) - Personal Responsibility and Health Awareness (2:57:10) - Addiction Rescue Course and Dopamine Revolution (3:00:05) - Memorial Day Sale and Health Ranger Store (3:03:35) - Final Thoughts and Encouragement (3:08:55) Watch more independent videos at http://www.brighteon.com/channel/hrreport ▶️ Support our mission by shopping at the Health Ranger Store - https://www.healthrangerstore.com ▶️ Check out exclusive deals and special offers at https://rangerdeals.com ▶️ Sign up for our newsletter to stay informed: https://www.naturalnews.com/Readerregistration.html Watch more exclusive videos here:
We love to hear from our listeners. Send us a message. On this week's episode of the Business of Biotech, Neil McFarlane, CEO at Zevra Therapeutics, talks about transitioning to a focused rare disease company through acquisitions, and building out a commercial organization. Neil explains the importance of working with rare disease patient advocacy groups, using AI to analyze electronic health records and claims data to identify and diagnose patients with Niemann-Pick disease type C, and adapting to regulatory inconsistencies around rare disease drug approval frameworks in the U.S. and Europe. Access this and hundreds of episodes of the Business of Biotech videocast under the Business of Biotech tab at lifescienceleader.com. Subscribe to our monthly Business of Biotech newsletter. Get in touch with guest and topic suggestions: ben.comer@lifescienceleader.comFind Ben Comer on LinkedIn: https://www.linkedin.com/in/bencomer/
In this episode of BioTalk with Rich Bendis, Sam Gussman-Toh, Portfolio Manager for the Small Business Program at ARPA-H, joins the conversation to discuss how the agency is creating new pathways for small businesses developing ambitious health technologies. Sam explains how the ARPA-H model differs from traditional federal funding programs, with a focus on moonshot health solutions, program manager-led portfolios, milestone-driven contracts, and a strong emphasis on moving technologies toward real-world use. He also discusses how the Small Business Program supports SBIR and STTR performers through Phase I, Phase II, Direct to Phase II, and Fast Track awards. The conversation highlights how ARPA-H is working with ambitious small businesses, including non-traditional companies and early-stage startups that may be working with the federal government for the first time. Sam also shares how commercialization support is built into the program, including ARPA-H's Entrepreneur-in-Residence partnership with BioHealth Innovation. Through that relationship, BHI EIRs help performers strengthen regulatory strategy, intellectual property planning, go-to-market strategy, reimbursement considerations, and other key commercialization needs. Sam also discusses ARPA-H's draft Small Business Program solicitation, the upcoming virtual Proposers' Day on June 11, and what companies should know about the application process, topic areas, technical pitches, and future funding opportunities. Editing and post-production work for this episode was provided by The Podcast Consultant. Sam Gussman-Toh is Portfolio Manager for the Small Business Program at ARPA-H, where he coordinates and oversees the agency's SBIR/STTR awards and commercialization support services for participating small businesses. Sam joined ARPA-H in 2022 and wrote the agency's first SBIR/STTR solicitation. He has held several roles in the Office of Commercialization and has worked closely with Program Managers to build the agency's commercialization infrastructure and strategy. Previously, Sam designed and managed rapid prototyping programs across agencies in the Department of War. His technical background is in computer science, with interests in computer vision, autonomous robotic systems, and computational pathology.
Are we alone? In this short-isode, Elton traces the bizarre, hilarious, and occasionally unhinged history of humanity's quest for alien communication. From Frank Drake's Equation in 1961, a mathematical roadmap for the search for extraterrestrial intelligence (SETI), to the times before radio, when our ideas were pure fantasy: he dives into the wild ideas and scams. Like, the 19th-century scheme to burn massive geometric messages onto the surface of Mars using a gargantuan, laser-focused mirror. For real.From those ambitious, largely insane, early visual signals to the iconic messages we've strapped to spaceships—we've spent centuries leaving a very expensive voicemail for an unknown recipient.We also explore the cosmic artifacts and phenomena that made us stop and whisper, "Is someone calling us?" Learn the true story behind the Black Knight Satellite (spoiler: it's an escaped blanket), the enduring mystery of the Wow! Signal, and the strange case of 'Oumuamua, the cigar-shaped interstellar visitor.Finally, we confront the ultimate cosmic buzzkill: the Fermi Paradox. If the galaxy should be crowded, "Where is everybody?" We discuss the terrifying ethical debate over intentional messaging (METI) and the chilling logic of the Dark Forest Theory. Tune in to find out why, even in crushing silence, we simply cannot stop shouting "Hello?" into the dark.GET THE BOOK: From AmazonFrom an Indie Book SellerBECOME AN Elton Reads A Book A Week CONTRIBUTOR HERE:Elton Reads A Book A Week PatreonBuy Me A Coffee!SOCIAL MEDIA! This is the LINK TREE!Join the Discord server!EMAIL: eltonreadsabookaweek@gmail.comThe following section is reserved for the people, places, things, and more that Elton probably offended in this episode--THE APOLOGIES SECTION: Martians, New Yorkers...again, TalkToAliens.com users, UFO conspiracy theorists, etc.A special thanks to Diedrich Bader and Jenna Fischer for all their inspiration.Tags: Drake Equation, Fermi Paradox, SETI, METI, Extraterrestrial Intelligence, Frank Drake, Cosmic Silence, Voyager Golden Records, Pioneer Plaques, Arecibo Message, Alien Communication, Interstellar Communication, Charles Cros, Wow! Signal, Black Knight Satellite, 'Oumuamua, Dark Forest Theory, UFO, Space Mystery, Long Delayed Echoes (LDEs), Baltic, Martian Lasers, Nikola Tesla, Cosmic Chat, Alien Conspiracies, Commercialization of Space, Space Hoaxes, Science Podcast, Short-isode, Elton Reads a Book a Week, Books and Reading, Infotainment, learning, fun, comedy, history
We're in London at the INTA 2026 Annual Meeting, but we're not doing a standard conference recap. We wanted to show how intellectual property work can be creative, inventive, and even fun, so we built THE INVENTIVE MINDSET GAME, a scenario game, and handed real IP lawyers a stack of tricky client prompts.Each prompt forces a choice: do you follow the client's exact instructions, take an inventive counseling path, bring in an AI assist tool, or throw a curveball and plan for the worst-case scenario. From a smart home invention to a viral character and an influencer launching a skincare line, we dig into the practical decisions behind patent strategy, trademark protection, and copyright, including how to think about prior art, claim scope, brand control, and what “commercialization” actually demands.We also talk about the unglamorous but critical details that can make or break an IP strategy: picking the right trademark classes, avoiding coverage that doesn't match the business, and sequencing filings when budgets are tight. If you're a founder, creator, in-house counsel, or just curious about how IP law works in the real world, you'll leave with clearer mental models and sharper questions to ask before you file anything.Subscribe for more stories and practical IP insights, share this with a friend building a brand, and leave a review if the game format helped you think differently about IP. What would you choose first: safe, inventive, AI-assisted, or curveball?Send us Fan MailCheck out "Protection for the Inventive Mind" – available now on Amazon in print and Kindle formats.The views and opinions expressed (by the host and guest(s)) in this podcast are strictly their own and do not necessarily reflect the official policy or position of the entities with which they may be affiliated. This podcast should in no way be construed as promoting or criticizing any particular government policy, institutional position, private interest or commercial entity. Any content provided is for informational and educational purposes only.
Commercialization decisions are shaping success earlier than ever in the product lifecycle, from value and access to launch strategy, deployment and stakeholder engagement. Conversations on Commercialization, a new spinoff of the Syneos Health Podcast, explores what this shift means for biopharma companies and what it takes to compete in a rapidly evolving market. Led by Tyler Cowan, Commercial Vice President at Syneos Health, and joined by a bench of expert co-hosts, the podcast brings together industry leaders to explore the trends, decisions and evolving commercial models defining success today.Subscribe to The Syneos Health Podcast: Conversations on Commercialization so you never miss an episode. The views expressed in this podcast belong solely to the speakers and do not represent those of their organization. If you want access to more future-focused, actionable insights to help biopharmaceutical companies better execute and succeed in a constantly evolving environment, visit the Syneos Health Insights Hub. The perspectives you'll find there are driven by dynamic research and crafted by subject matter experts focused on real answers to help guide decision-making and investment. You can find it all at https://www.syneoshealth.com/insights-hub. Like what you're hearing? Be sure to rate and review us! We want to hear from you! If there's a topic you'd like us to cover on a future episode, contact us at podcast@syneoshealth.com.
In this episode, Richard Clapp, retired principal consultant from DuPont, joins co-hosts Heather Allain and Marc Cook for a discussion on the role of materials expertise in process commercialization. Drawing on decades of industry experience, Richard outlines the three primary types of process commercialization and the institutional challenges companies often face when scaling new processes from the bench to production. The conversation explores how impurities, feedstock variability, and solids handling can introduce unexpected complications, as well as why engineers tend to take conservative approaches to materials recommendations during commercialization efforts. Richard also breaks down common “show stoppers” and explains the importance of the three C's—corrosion, compatibility, and clean-up—when evaluating process systems. Additional topics include corrosion testing at both bench and pilot scale, the subtle but important differences that can exist between seemingly identical plants, considerations when using toll manufacturers for pilot operations, and practical advice for organizations navigating process commercialization projects. This episode is sponsored by Tricor Metals and Rolled Alloys. Corrosion Chronicles is produced by Association Briefings.
Welcome to episode #1034 of Thinking With Mitch Joel (formerly Six Pixels of Separation). At a time when the lines between culture, commerce and identity feel increasingly blurred, few people understand how value is actually constructed… and reconstructed… better than Douglas Woodham. A former President of the Americas at Christie's and a longtime advisor through his firm Art Fiduciary Advisors, Doug brings a rare dual lens to the conversation… equal parts economist and art obsessive. With a PhD in economics and decades spent inside the machinery of the global art market, he has seen firsthand how artists move from obscurity to icon status… and how markets, narratives and power structures shape that journey . His latest book, Jean-Michel Basquiat - The Making of an Icon, goes far beyond biography to examine how one artist's legacy was not just created… but carefully engineered. In this conversation, Doug explores the intersection of art and economics, unpacking how scarcity, status and human behavior drive the desire to collect… and why ownership has become increasingly performative in a social media age. He challenges the romantic notion that value is purely about the work itself, pointing instead to branding, cultural timing and strategic stewardship… particularly in Basquiat's posthumous rise. We also dig into the broader shifts reshaping the art world… from the declining cultural centrality of fine art to the rise of alternative collectibles, the failure of NFTs to gain traction in traditional markets, and the fragile economics behind fractional ownership models. What emerges is a sharper understanding that art is not just about beauty or expression… it is about markets, narratives and belief systems that determine what is worth owning… and why. Enjoy the conversation… Running time: 1:04:35. Hello from beautiful Montreal. Listen and subscribe over at Apple Podcasts. Listen and subscribe over at Spotify. Please visit and leave comments on the blog - Thinking With Mitch Joel. Feel free to connect to me directly on LinkedIn. Check out ThinkersOne. Here is my conversation with Douglas Woodham. Jean-Michel Basquiat - The Making of an Icon. Art Fiduciary Advisors. Art Collecting Today. Follow Doug on Instagram. Follow Doug on LinkedIn. Chapters: (00:00) - Introduction to Doug Woodham and His Expertise. (02:42) - The Life and Legacy of Jean-Michel Basquiat. (04:48) - Connecting Art and Economics. (08:45) - Human Behavior and the Desire for Collectibles. (12:10) - The Shift in Art Collecting Trends. (15:42) - NFTs and Their Impact on the Art Market. (20:29) - Artist Compensation and Ownership Rights. (24:28) - Cultural Relevance of Fine Art Today. (27:58) - The Psychology of Collecting and Scarcity. (32:37) - The Business of Scarcity in Consumer Brands. (35:15) - The Importance of Secondary Markets in Collectibles. (40:10) - The Evolution of Basquiat's Brand Posthumously. (54:51) - The Intersection of Art and Commercialization. (59:53) - Fractional Ownership in Art Investments.
Humans have been exchanging tokens of friendship since before recorded history. From calling cards to Valentines to Christmas cards, the modern greeting card industry evolved. Research: “America’s First Christmas Card.” Albany Institute of History and Art. https://www.albanyinstitute.org/online-exhibition/50-objects/section/america-s-first-christmas-card Britannica Editors. "scarab". Encyclopedia Britannica, 3 Apr. 2014, https://www.britannica.com/topic/scarab Britannica Editors. "greeting card". Encyclopedia Britannica, 15 Mar. 2024, https://www.britannica.com/topic/greeting-card Brown, Ellen F. “Christmas, Inc.: A Brief History of the Holiday Card.” JSTOR Daily. Dec. 20, 2015. https://daily.jstor.org/history-christmas-card-holiday-card/ Chase, Ernest Dudley. “The Romance of Greeting Cards.” Rust Craft. Cambridge, MA. 1956. “Dali at Hallmark.” Hallmark Art Collection. https://www.hallmarkartcollection.com/creatively-thinking/stories/dali-at-hallmark/ “Esther Howland 1847.” Mount Holyoke. https://www.mtholyoke.edu/directory/alum/esther-howland Evans, Elaine Altman. “The Sacred Scarab, Occasional Paper.” McClung Museum of Natural History and Culture. University of Tennessee. January 1, 1996. https://mcclungmuseum.utk.edu/1996/01/01/sacred-scarab/ Greeting Card Association. “The History of Greeting Cards.” https://www.greetingcard.org/history/ Hanc, John. “The History of the Christmas Card.” Smithsonian. Dec. 9, 2015. https://www.smithsonianmag.com/history/history-christmas-card-180957487/ Henry, William E. “Art and Cultural Symbolism: A Psychological Study of Greeting Cards.” The Journal of Aesthetics and Art Criticism, vol. 6, no. 1, 1947, pp. 36–44. JSTOR, https://doi.org/10.2307/426176 Kavanagh, Marybeth. “Louis Prang, Father of the American Christmas Card.” The New York Historical. Dec. 19, 2012. https://www.nyhistory.org/blogs/prang Koon, Wee Kek. “How ancient Chinese new year cards went from elites’ greetings to bribery instruments.” South China Morning Post. Jan. 31, 2026. https://www.scmp.com/lifestyle/chinese-culture/article/3341675/how-ancient-chinese-new-year-cards-went-elites-greetings-bribery-instruments?module=perpetual_scroll_0&pgtype=article Korolkov, Maxim. “‘Greeting Tablets’ in Early China: Some Traits of the Communicative Etiquette of Officialdom in Light of Newly Excavated Inscriptions.” T’oung Pao, vol. 98, no. 4/5, 2012, pp. 295–348. JSTOR, http://www.jstor.org/stable/41725988 Lee, Ruth Webb. “A History of Valentines.” 1984. Newberry, Percy E. “Scarabs: An Introduction to the Study of Egyptian Seals and Signet Rings.” London. Archibald Constable and Co. Ltd. 1908. https://dn790001.ca.archive.org/0/items/scarabsintroduc00newbuoft/scarabsintroduc00newbuoft.pdf Purcell, Denise. “Authentic Messaging and Independent Makers Drive Greeting Cards' Next-Gen Relevance.” U.S. Chamber of Commerce. https://www.uschamber.com/co/good-company/launch-pad/greeting-card-next-gen-relevance#:~:text=The%20category%20is%20massive:%20According,card%20market%20at%20$7%20billion. Grafton, Samuel. “Holly Leaf and Copper Plate.” The North American Review, vol. 226, no. 6, 1928, pp. 660–64. JSTOR, http://www.jstor.org/stable/25110633 Shoichet, Catherine E. “This ‘visionary’ woman changed the way many Americans celebrate Valentine’s Day.” CNN. Feb. 14, 2024. https://edition.cnn.com/2024/02/13/style/esther-howland-valentines-card-history-cec Schmidt, Leigh Eric. “The Commercialization of the Calendar: American Holidays and the Culture of Consumption, 1870-1930.” The Journal of American History, vol. 78, no. 3, 1991, pp. 887–916. JSTOR, https://doi.org/10.2307/2078795 Stupperich, Andy. “Art Education: Louis Prang's Christmas Card Competitions.” The Henry Ford Museum. January 29, 2026. https://www.thehenryford.org/collections/explore/articles/art-education-louis-prang%27s-christmas-card-competitions Terrell, Ellen. “Esther Howland and the Business of Love.” Library of Congress. March 23, 2016. https://blogs.loc.gov/inside_adams/2016/03/esther-howland-and-the-business-of-love/ “World's first printed Valentine's Card.” A History of the World. BBC. 2014. https://www.bbc.co.uk/ahistoryoftheworld/objects/L1NM_6mWRymAMKXcRDlXJA Wright, Helena E. “A winning design: Prang’s Christmas card contests of the 1880s.” National Museum of American History. December 23, 2019. https://americanhistory.si.edu/explore/stories/winning-design-prangs-christmas-card-contests-1880s See omnystudio.com/listener for privacy information.
Brian Webster, President and CEO of Kestra Medical Technologies (Nasdaq: KMTS), joins Medtech Talk to discuss his 30-year career in cardiac defibrillation and the road to founding Kestra. With host Swaril Mathur, Webster unpacks learnings from leading through decades of repeated acquisitions, divestitures, and restructurings — and keeping the team motivated through it all. Their conversation explores what it takes to commercialize a rental fleet model with outsourced manufacturing, revenue cycle management, and payer contracts, as well as closing with the decision to IPO and staying steady in volatile markets by focusing on execution fundamentals. Subscribe, share this with a MedTech operator who's scaling something hard, and leave a rating or review with the leadership lesson that hit you most. Medtech Talk Links: Cambridge Healthtech Institute Medtech Talk Gilde Healthcare MicroTransponderLinks: MicroTransponder Kestra Medical Technologies: Kestra Medical Technologies
In this episode of the Global Medical Device Podcast, host Etienne Nichols sits down with John Schindler, CEO of Liquet Medical, for a "MedTech Founder 101" masterclass. With over 25 years of experience at industry giants like Atrium and Merit Medical, Schindler shares the "painful reality checks" that come when transitioning from the structured umbrella of a large corporation to the high-stakes, resource-dependent world of a startup.The conversation dives deep into the philosophy of "novel but simple" technology. Schindler explains why simplicity is often harder to fund but essential for physician adoption and long-term market success. He challenges the current industry obsession with over-engineered solutions, arguing that the pendulum is swinging back toward intuitive, easy-to-use devices that don't "break the system" of healthcare delivery.Finally, the discussion covers the tactical realities of commercialization, including the nuances of the "Valley of Death." Schindler outlines why a limited market release is often superior to broad distribution and emphasizes the importance of building strategic enterprise value through intentional clinical data that speaks to both regulatory bodies and hospital value analysis committees.Key Timestamps00:45 – Introduction to John Schindler and Liquet Medical's mission.02:15 – The Corporate vs. Startup Reality: Losing the safety net of big-company resources.04:30 – Simplicity vs. Complexity: Why investors favor "shiny" tech but physicians crave simplicity.07:50 – The MedTech Innovator Experience: Leveraging human capital and "pressure testing" your company.10:15 – Unlearning Corporate Silos: The necessity of radical collaboration in early-stage teams.12:40 – Clinical Data Strategies: Moving beyond "clinical wins" to hospital value analysis.15:30 – Establishing "Soft Endpoints" for payers and rural healthcare settings.18:20 – Negotiating as a Cash-Strapped Startup: Approaching vendors and regulatory services with humility.21:10 – The Regulatory Chess Game: Why early engagement with the FDA prevents timeline resets.24:35 – Commercialization and the 510(k) vs. IDE strategy.27:15 – The Risks of Distribution Agreements: Why products "fall to the bottom of the bag."Quotes"The complexity can actually break the system in some ways. Physicians always gravitate back towards simplicity—things that are easy for them to wrap their heads around." - John SchindlerTakeawaysMaster the Holistic Approach: Founders should seek exposure to every facet of the business—sales, management, and business development—to understand how their innovation responds "in the trenches."Everything is Negotiable: Especially for cash-strapped startups, approaching regulatory and quality service providers with humility can lead to flexible contract structures that help build a strong foundation early.Clinical Data is for Post-Submission too: Don't just collect data to satisfy the FDA; identify "soft endpoints" that prove economic value to hospital value analysis committees and payers.Control Your Launch: A Limited Market Release (LMR) allows a startup to "get their nose bloodied" on a small scale, refining the sales methodology before attempting to scale nationally.Avoid the "Bottom of the Bag" Syndrome: Be cautious with large distribution agreements early on. If the sales force isn't properly incentivized or trained, your product may be ignored in favor of higher-margin legacy items.ReferencesMedTech Innovator: The world's largest accelerator for medical device companies.Hal Stowe (Eurofins): Referenced for his recent article on the strategic value of a purposeful regulatory strategy.Etienne Nichols: Connect with the host on LinkedIn.MedTech 101: The 510(k) vs. IDEIn this episode, John mentions having a 510(k) clearance but needing an IDE trial.510(k): Think of this as the "Me Too" pathway. You are telling the FDA your device is "substantially equivalent" to one already on the market. It gets you through the door, but often with limited claims (a "tool claim").IDE (Investigational Device Exemption): This allows your device to be used in a clinical study to collect safety and effectiveness data. It's like a "permit" to do the deep research needed to prove your device can treat a specific, high-stakes condition like a pulmonary embolism.SponsorsThis episode is brought to you by Greenlight Guru. For MedTech founders looking to avoid the regulatory headaches discussed today, Greenlight Guru offers the only dedicated Medical Device Success Platform. From their industry-leading QMS (Quality Management System) to their robust EDC (Electronic Data Capture) solutions, they help you move from concept to commercialization faster while staying compliant. Connect your quality data to your clinical trials to build the "ring fence" of value John Schindler discussed.Feedback Call-to-ActionWe want to hear from you. Did John's take on simplicity change how you view your product roadmap? Do you have a "Founder 101" topic you want us to cover? Send your thoughts, reviews, and suggestions to podcast@greenlight.guru. We read every email and pride ourselves on providing personalized responses to our MedTech community.
No Priors: Artificial Intelligence | Machine Learning | Technology | Startups
What happens when you apply the scaling laws of large language models to the physical work of atoms? Elad Gil sits down with Liam Fedus, co-founder at Periodic Labs, which is pioneering an AI foundation lab for atoms. Liam discusses how he pivoted from dark matter physics research to the front lines of artificial intelligence, including stints at Google Brain and working on ChatGPT at OpenAI. He talks about how Periodic is connecting massive language models to the physical world to overcome data bottlenecks in material science. Liam also shares how they use language models as an orchestration layer operating alongside specialized neural nets to run closed-loop physical experiments. They also explore the future of AGI and ASI, as well as the role of robotics in lab automation. Sign up for new podcasts every week. Email feedback to show@no-priors.com Follow us on Twitter: @NoPriorsPod | @Saranormous | @EladGil | @LiamFedus | @periodiclabs Chapters: 00:00 – Cold Open 00:05 – Liam Fedus Introduction 00:39 – Liam's Background at Google Brain, OpenAI 05:14 – From ChatGPT to Materials and Atoms 06:34 – Training Data in the Physical World 09:52 – Generalization Across Domains 11:31 – Models as an Orchestration Layer 12:48 – Commercialization and Business Model 16:10 – How Periodic's Success May Shape the Future 17:45 – Multidisciplinary Scaling 19:41 – Capital and Compute 21:12 – Hiring at Periodic 21:44 – Thoughts on AGI and ASI 23:30 – Timeline for Machine-Directed Self-Improvement 25:39 – Automation and Data Generation 27:59 – Why Liam is Excited About the Future of Robotics 29:25 – Conclusion
In this episode, Rick Peng, Digital Ventures Lead in Memorial Sloan Kettering Cancer Center (MSK) Office of Entrepreneurship & Commercialization & Natalia Summerville, PhD, Director of Decision Intelligence at Memorial Sloan Kettering Cancer Center, discuss how MSK is advancing AI across clinical care and research while building a robust governance model. They share insights on balancing innovation with safety, ensuring accountability, and driving real impact through thoughtful AI deployment and monitoring.
In this episode, Vineet Gupta, PhD, FASN, Vice President of the Office of Innovation and Commercialization and CEO of Medical Branch Innovations at The University of Texas Medical Branch, discusses embedding innovation as a fourth pillar alongside clinical care, research, and education. He shares how strategic focus areas such as brain health, kidney health, healthy aging, and AI driven solutions are advancing commercialization, public private partnerships, and systemwide transformation.
PREVIEW FOR LATER TODAY Guest: Bob Zimmerman. Zimmerman details Starfish's $154 million Pentagoncontract using space tugs to service and de-orbit satellites, highlighting the growing commercialization of low Earthorbit.1957