Podcasts about Mechanism

Unpacking market volatility, stablecoins, and Kraken's strategy with Co-CEO David Ripley. Kraken Co-CEO David Ripley joins CoinDesk's Jennifer Sanasie and Andy Baehr to discuss the firm's record-breaking Q3 growth and its strategy to merge traditional finance with crypto by moving into futures and equities trading. Ripley highlights the "network effect" that has made stablecoins the default settlement currency for exchanges and integrated crypto businesses. He also addresses the compression of Bitcoin volatility and how Kraken is catering to both seasoned individual pro traders and the broader, derivatives-shy retail consumer base. - Break the cycle of exploitation. Break down the barriers to truth. Break into the next generation of privacy. Break Free. Free to scroll without being monetized. Free from censorship. Freedom without fear. We deserve more when it comes to privacy. Experience the next generation of blockchain that is private and inclusive by design. Break free with Midnight, visit ⁠⁠⁠⁠⁠⁠midnight.network/break-free⁠⁠⁠⁠⁠⁠ - OwlTing (Nasdaq: OWLS) is building invisible rails for global payments. With OwlPay, businesses and users can bridge fiat and stablecoins, send money instantly across borders, and access stablecoin checkout at lower costs. Licensed worldwide, OwlTing delivers secure, compliant, and regulated infrastructure for the digital economy. Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠owlting.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. - Genius Group has partnered with CoinDesk for Bitcoin Treasury Month, launching the Genius x CoinDesk Quest. Participants can join the Bitcoin Academy, complete free microcourses from experts like Natalie Brunell and Saifedean Ammous, and enter to win 1,000,000 GEMs (worth 1 BTC) promoting bitcoin education and adoption. Learn more at: ⁠https://www.geniusgroup.ai/coindesk-bitcoin-treasury-month/⁠ - This episode was hosted by Jennifer Sanasie and Andy Baehr.

Unpacking market volatility, stablecoins, and Kraken's strategy with Co-CEO David Ripley. Kraken Co-CEO David Ripley joins CoinDesk's Jennifer Sanasie and Andy Baehr to discuss the firm's record-breaking Q3 growth and its strategy to merge traditional finance with crypto by moving into futures and equities trading. Ripley highlights the "network effect" that has made stablecoins the default settlement currency for exchanges and integrated crypto businesses. He also addresses the compression of Bitcoin volatility and how Kraken is catering to both seasoned individual pro traders and the broader, derivatives-shy retail consumer base. - Break the cycle of exploitation. Break down the barriers to truth. Break into the next generation of privacy. Break Free. Free to scroll without being monetized. Free from censorship. Freedom without fear. We deserve more when it comes to privacy. Experience the next generation of blockchain that is private and inclusive by design. Break free with Midnight, visit ⁠⁠⁠⁠⁠⁠midnight.network/break-free⁠⁠⁠⁠⁠⁠ - OwlTing (Nasdaq: OWLS) is building invisible rails for global payments. With OwlPay, businesses and users can bridge fiat and stablecoins, send money instantly across borders, and access stablecoin checkout at lower costs. Licensed worldwide, OwlTing delivers secure, compliant, and regulated infrastructure for the digital economy. Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠owlting.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. - Genius Group has partnered with CoinDesk for Bitcoin Treasury Month, launching the Genius x CoinDesk Quest. Participants can join the Bitcoin Academy, complete free microcourses from experts like Natalie Brunell and Saifedean Ammous, and enter to win 1,000,000 GEMs (worth 1 BTC) promoting bitcoin education and adoption. Learn more at: ⁠https://www.geniusgroup.ai/coindesk-bitcoin-treasury-month/⁠ - This episode was hosted by Jennifer Sanasie and Andy Baehr.

Unpacking market volatility, stablecoins, and Kraken's strategy with Co-CEO David Ripley. Kraken Co-CEO David Ripley joins CoinDesk's Jennifer Sanasie and Andy Baehr to discuss the firm's record-breaking Q3 growth and its strategy to merge traditional finance with crypto by moving into futures and equities trading. Ripley highlights the "network effect" that has made stablecoins the default settlement currency for exchanges and integrated crypto businesses. He also addresses the compression of Bitcoin volatility and how Kraken is catering to both seasoned individual pro traders and the broader, derivatives-shy retail consumer base. - Break the cycle of exploitation. Break down the barriers to truth. Break into the next generation of privacy. Break Free. Free to scroll without being monetized. Free from censorship. Freedom without fear. We deserve more when it comes to privacy. Experience the next generation of blockchain that is private and inclusive by design. Break free with Midnight, visit ⁠⁠⁠⁠⁠⁠midnight.network/break-free⁠⁠⁠⁠⁠⁠ - OwlTing (Nasdaq: OWLS) is building invisible rails for global payments. With OwlPay, businesses and users can bridge fiat and stablecoins, send money instantly across borders, and access stablecoin checkout at lower costs. Licensed worldwide, OwlTing delivers secure, compliant, and regulated infrastructure for the digital economy. Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠owlting.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. - Genius Group has partnered with CoinDesk for Bitcoin Treasury Month, launching the Genius x CoinDesk Quest. Participants can join the Bitcoin Academy, complete free microcourses from experts like Natalie Brunell and Saifedean Ammous, and enter to win 1,000,000 GEMs (worth 1 BTC) promoting bitcoin education and adoption. Learn more at: ⁠https://www.geniusgroup.ai/coindesk-bitcoin-treasury-month/⁠ - This episode was hosted by Jennifer Sanasie and Andy Baehr.

In this episode, I am speaking with Neuroscience Expert | Inventor of BrainTap® | Brain Fitness Pioneer, Dr​​ Patrick K. Porter. Dr. Porter has spent his life asking a radical question: What if we could train the brain like a muscle and transform lives without pills, struggle, or guesswork? Introduced to the power of mind training by his father at an early age, Dr. Porter's lifelong passion has been exploring how visualization, brainwave science, and neuroplasticity can unlock human potential. As a pioneer in brainwave entertainment since the 1980s, Dr. Porter saw possibilities where others saw limitations. He co-developed the first personal brain training device long before "biohacking" became a buzzword, and continues to do so today. He's the mind behind BrainTap®—a revolutionary platform trusted by over 120,000 users, professional athletes, and 3,000+ health clinics worldwide. His work, backed by 30+ clinical studies and spotlighted across The Wall Street Journal, CNN, and The Joe Rogan Experience, proves that brain fitness isn't about puzzles or trends—it's about science, balance, and unlocking the brain's innate ability to heal, perform, and thrive. Through BrainTap and his upcoming book, Brain Fitness Blueprint, Dr. Porter is leading a global movement to help millions reclaim their mental clarity, emotional resilience, and human potential—one brain at a time. HIGHLIGHTS 00:01:00 - Journey into Psychology and Technology 00:02:00 - The Birth of BrainTap 00:03:00 - Understanding Neuroplasticity 00:04:00 - Movement and Brain Health 00:05:00 - The Physiological Crisis 00:06:00 - The Role of Light and Frequency 00:07:00 - The Science of Energy and ATP 00:08:00 - Breath and Emotional Health 00:09:00 - The Power of Positive Thinking 00:11:00 - The Brain's Energy Needs 00:12:00 - The Role of Meditation and Brain Fitness 00:13:00 - The Brain's Capacity for Change 00:15:00 - The Mechanism of BrainTap Sessions 00:16:00 - The Science Behind Brainwave Frequencies 00:17:00 - The Synchronization of Brainwaves 00:18:00 - The Role of the Lymphatic System 00:19:00 - The Connection Between Heart and Brain 00:20:00 - Conclusion and Call to Action Connect with Dr. Patrick Porter Instagram:  https://www.instagram.com/drpatrickporter Instagram: https://www.instagram.com/braintaptech Website: https://braintap.com/Website: https://drpatrickporter.com/ Marsha Vanwynsberghe — NLP Storytelling Trainer, OUTSPOKEN NLP Coaching Certification, Author, Speaker, and Podcaster Download FREE "You Are Supported" Hypnosis and Subliminal Bundle HERE  Join the next cohort of OUTSPOKEN NLP Coaching Certification (kick-off in March 2025) HERE Learn more about changing the Stories We Tell Ourselves Digital Program HERE. Use Code PODCAST to receive 20% off. Code FASTACTION20 Tap the "Follow" button never to miss a show, and if you love the show, please feel free to tag me on social media, share it with a friend, or leave me a rating and review. This helps the show grow! Website: www.marshavanw.comConnect on IG. Click HERESubscribe on YouTube. Click HERE  

Regenerative aesthetics continues to evolve—and polynucleotides are taking center stage. These powerful bioactive molecules are changing the game when it comes to collagen stimulation, skin healing, and true rejuvenation.

Humanity has long misunderstood fertility. Part 76 of The Story of Creation is a profound exploration where Michelle reveals that fertility energy is not merely physical—it is the universal mechanism of creation itself. Every idea, curiosity, and intention you hold carries the potential to shape reality. From a universal creation perspective, matter is the final 1–2% of a much larger energetic equation. Everything begins with vibration. When you understand energy before matter, you begin to see that your life, your fulfillment, and even your purpose unfold through curiosity and intention. Michelle uncovers how the human brain has been conditioned to seek satisfaction in the physical, mistaking fleeting pleasure for creation. Yet, true fertility—the energy of existence—comes from your soul's vibration expanding beyond limitation. Through this revelation, you'll understand how human potential is born from freedom, curiosity, and the courage to explore who you are without fear. This episode dismantles the illusion that fertility is limited to reproduction. Instead, it reveals that every aspect of your life—your passions, projects, relationships, and ideas—exists as a reflection of your spiritual evolution. Fertility is the process by which you, as a Creator, bring your inner world to life. Learn how to transform shame into wisdom, rediscover fulfillment through energetic awareness, and understand that all information in existence—past, present, and future—is available through vibration. The history of humanity and existence is not lost; it is written in energy, encoded in your DNA, waiting to be remembered. Watch this exploration to reconnect with the universal truth of who you are: a living manifestation of the Creator's original intention, here to evolve consciousness and restore balance to existence through your participation in creation itself. 0:00 – The Foundation of Universal Creation 2:05 – Understanding Fertility Energy Beyond the Physical 3:50 – How Beliefs Shape Reality and Creation 6:01 – Fertility as the Mechanism of Manifestation 7:33 – The Energy That Creates Matter 10:08 – Misunderstanding Sex and the True Nature of Fertility: The Vortex of Creation Explained 12:10 – Freedom, Curiosity, and Fulfillment 13:28 – Reconnecting to Your Creative Power 14:16 – Why Depression and Anxiety Disconnect You from Creation 15:01 – Curiosity as the Catalyst of Evolution 19:19 – Shame, Secrets, and Hidden Wisdom 20:43 – Energy Holds All Information in Existence 26:33 – Creating Your Legacy 31:46 – Human Potential and the Future of Evolution ✨ Join Michelle and the Universal Council to explore the profound truth of existence, your role in evolution, and the power within your soul. Top Keywords: Fertility, Universal truth, soul alignment, consciousness evolution, human origins, spiritual awakening, self-awareness, universal perspective, creation mechanics, authentic human podcast, life purpose, reverence, humanity's evolution, cosmic power, inner fulfillment, universal communication. Discover more at: michellevickers.com/community Michelle Vickers is a researcher, communicator, and explorer of creation, existence, and evolution. Through her direct connection with the Creator and Universal Beings, Michelle translates universal communication into practical understanding—bridging science and spirituality to reveal the hidden mechanics of consciousness. Her work empowers humanity to remember the truth of creation and access the full potential of their soul, restoring integrity, purpose, and alignment between energy and matter. ➤ Subscribe to The Authentic Human Podcast to dive deeper into universal truth. ➤ Comment below: What is your deepest question you've never asked — start now.

Are supplements helping you — or wasting your money? In this episode of The Exam Room Podcast, Dr. Gemma Newman joins Chuck Carroll to break down the science, myths, and marketing behind the multibillion-dollar supplement industry. Discover which supplements are truly worth taking, which can be harmful in excess, and how to build better health through a whole-food, plant-based diet. Whether you're taking vitamin B12, vitamin D, omega-3, or a daily multivitamin, Dr. Newman explains how to personalize your nutrition safely and effectively. In This Episode: - The truth about supplements and what's actually backed by science - Why multivitamins don't extend lifespan — and can sometimes harm your health - How to get vitamin B12 safely - The risks of "natural" supplements - The difference between fish oil vs. algae-based omega-3s - Dr. Newman's SMART method: Science, Mechanism, Aim, Risk vs. Benefit, Tracking - How to spot fake supplement ads and AI deepfakes online Known as The Plant Power Doctor, Dr. Newman is a respected physician and lifestyle medicine expert helping patients reverse chronic disease through evidence-based nutrition and lifestyle change.

In Podcast 61, I sit with Dr. Karen Hurd to discuss HRT.Episode Focus: Re-examining the risks of Hormone Replacement Therapy (HRT) in light of new scientific rhetoric, The biological mechanism of hormonal damage, and the power of lifestyle in navigating menopause.1. The Core Scientific Risk: DNA DamageDr. Hurd challenges the idea that "bioidentical" hormones are inherently safer than synthetic ones.The Mechanism of Action: Hormones (both endogenous/innate and exogenous/prescribed) are very small molecules known scientifically as nuclear receptors.Crossing Barriers: These molecules are so tiny that they can bypass normal cellular defenses by diffusing directly through the cell membrane (plasma membrane) and the nuclear envelope.The DNA Barrage: Once inside the nucleus, the hormone-transcription factor complex randomly attaches to the DNA3. This is not a one-time event; a daily pill or patch creates a constant barrage on the nuclear envelope.Mutating Genes: If this random attachment occurs at a critical site, such as the P53 gene (often affected in nearly 50% of hormonally receptive cancers) 5, it can disable the cell's stop mechanism (stop codon)6. The damaged cell then reproduces daughter cells carrying the same mutation, leading to tumors.The Power of Diet and LifestyleThe Natural Menopause: Menopausal symptoms (bone loss, brain fog, hot flashes) are often the result of entering menopause in a non-healthy stateEstrogen Drivers: Hormones are naturally produced, but their excess can be driven by lifestyle. Caffeine is a more powerful driver of estrogen production than sugar.Adrenal Role: The adrenal glands are meant to take over producing weaker, protective estrogens after menopause16. Stressing the adrenals with caffeine, sugar, and over-exercising diverts resources away from hormone production, leading to symptoms like vaginal atrophy and hot flashes.The Bean Protocol Solution: Eating soluble fiber (like beans) does not stop innate hormone production; rather, the fiber acts by carrying out what the liver dumps into the gut.. This prevents the excessive recycling (up to 72 times daily) of hormones, allowing the body to naturally bring elevated estrogen levels back down to a safe, post-menopausal levelYou can learn more about working with Karen Hurd at www.karenhurd.comand you can learn more about my courses and working with me at www.youregreat.comWishing you well on your human journey.X

The PREVENT score in hypertension, GLP-1 mechanism of action in cardiovascular disease, CAD type and statin benefit, and the problem with hospitalization endpoints in HF trials are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Is the PREVENT Calculator Best for Determining CVD Risk? Insights From a Post Hoc Analysis of SPRINT Trial https://www.medscape.com/viewarticle/prevent-calculator-best-determining-cvd-risk-insights-post-2025a1000svo PREVENT Calculator https://doi.org/10.1016/j.jacc.2025.07.037 SPRINT Trial https://www.nejm.org/doi/full/10.1056/NEJMoa1511939 II GLP-1 Mechanism of Action in CV Disease Analysis of SELECT Trial 10.1016/S0140-6736(25)01375-3 External Link SELECT trial https://www.nejm.org/doi/full/10.1056/NEJMoa2307563 III Statins and CAD Phenotype on CTA and Outcomes Interactions Between Statin Use, CAD Phenotypes on CTA  https://www.jacc.org/doi/10.1016/j.jcmg.2025.05.018 Statin Use for Primary Prevention of CVD https://jamanetwork.com/journals/jama/fullarticle/2795522 IV HHF Endpoints in Heart Failure Trials The Problem with Hospitalization Endpoints in HF Trials https://onlinelibrary.wiley.com/doi/10.1002/ejhf.70070 You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net

Straight out of college, today's guest wanted to make an impact on the African continent. For him, the best way to do this was through policy or the work of a nonprofit. But early into that work, it was the pull of business and its potential to drive social value that pulled him in. Today's guest, David Ellis, is the founder and CEO of Hatch Africa, a company seeking to bring a new business model to sub-Saharan Africa to, in their words, bring eggs and chickens to every household. Special Guest: David Ellis.

With $4 million to invest, should you secure a high-end condo or stretch into the landed segment? Melvin Lim from PropertyLimBrothers uses the Buying Power Triangle to explore how price thresholds, buyer profiles and exit potential interact in today's property landscape. The $4.5 million mark emerges as a critical pivot—especially for those aiming to future-proof their real estate decisions.   Cooling measures like the 60% ABSD for foreigners have reshaped transaction volumes, pushing local buyers to the forefront. Melvin examines how this shift impacts the buyer pool, resale strategies, and why understanding the aspiration ladder matters more than ever when planning your next move.   If you're navigating property investment around the $4M mark, this episode offers grounded thinking on strategic positioning and long-term exit planning.   0:00 - Teaser 0:54 - Q&A Time - If I have $4 mil, Condo or Landed? 1:13 - Intro to 3 Mechanisms 1:31 - Mechanism 1: Who are the Buyers 1:38 - Chart: New Sale Non-Landed Homes by Foreigners & PRs 2:54 - Chart: Resale Non-Landed Homes by Foreigners & PRs 3:25 - Understanding Buying Power Triangle 3:35 - Element 1: Affordability 5:12 - Element 2: Sweet Spot Pricing 7:30 - Element 3: Who are the Buyers 8:23 - Every Singaporean's Aspiration 10:20 - Finding the Sweet Spot 11:18 - Conclusion & Outro

Public RSS Feeds vs Private RSS Feeds for Best Podcast SEO Distribution Practices with Favour Obasi-Ike | Sign up for exclusive SEO insights.In this podcast episode, Favour provides an extensive comparison between public podcast RSS feeds and private podcast RSS feeds, offering guidance on how to choose the appropriate option for one's needs, particularly for business growth. A public podcast is openly accessible on various platforms and directories like Apple Podcasts and Spotify, serving as a powerful tool for brand building, content marketing, and increasing accessibility. Conversely, a private podcast is characterized by requiring authentication for access, making it suitable for exclusive content, internal corporate training, or paid subscription communities, with platforms like Supercast and Hello Audio recommended for this purpose. Favour stresses that consistent content publication and maximizing RSS feed distribution to various directories are crucial for public podcast success, while noting that starting with a public podcast is often advisable before transitioning to a private, often monetized, model.The Public RSS Feed: Maximizing Reach and DiscoverabilityA public podcast RSS feed is a publicly listed show available on third-party platforms and directories. It is designed for open access and broad distribution.• Definition: A public feed is accessible to anyone on podcast players and websites without requiring a login or payment. It operates on a one-to-many distribution model, where a single RSS feed from a hosting platform is submitted to numerous podcast directories.• Analogy: The structure is comparable to a website, which has a backend hosting provider (e.g., GoDaddy, Hostinger) and a front-facing content management system (CMS) or website that users interact with. In podcasting, the hosting platform holds the audio files, and the directories (players) make them accessible to listeners.• Mechanism of Reach: The key to a public podcast's success is submitting its RSS feed to as many directories as possible. Each directory is a separate website or application, and being listed on 30 different players means 30 distinct online entities are linking back to the podcast, significantly enhancing its digital footprint and discoverability.The Private RSS Feed: Monetization and ExclusivityA private podcast RSS feed is intentionally not listed on public directories and is structured to control access.• Definition: A private feed is ineligible for public listing because it requires authentication—a user must sign up, log in, or pay to access the content. This creates a secure and exclusive listening experience.• Analogy: This model is comparable to subscription-based streaming services like Netflix or Amazon Prime. Users pay a fee to access a database of proprietary content. A private podcast operates on the same principle, offering exclusive audio or video content to a select audience.• Mechanism of Access: Access is granted only after a specific action is taken by the user, typically involving payment or registration. This makes it a powerful tool for delivering premium content, courses, internal communications, or community-specific updates.--------------------------------------------------------------------------------Next Steps for Digital Marketing + SEO Services:>> ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Need SEO Services? 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European Rocket Revolution: HyImpulse, a German rocket manufacturer, has secured €45 million in funding to accelerate the development of their SL1 rocket. This three-stage rocket, standing 33 meters tall, aims for its inaugural flight in 2027 and promises to enhance Europe's competitiveness in space access, especially for smaller payloads.Innovative Space Armor: Atomic 6 has introduced Space Armor, a new composite material designed to protect satellites and astronauts from space debris. This lightweight, customizable shield absorbs impacts without generating secondary fragments, potentially revolutionizing safety in low Earth orbit.Black Hole Jet Dynamics: Researchers at Goda University have shed light on how supermassive black holes produce powerful jets of plasma. Utilizing advanced simulations, they reveal the role of magnetic reconnection in enhancing energy extraction, contributing to our understanding of galaxy evolution.Inflated White Dwarfs Explained: New findings on white dwarfs in short-period binary systems indicate that tidal heating causes these stellar remnants to expand and heat up significantly. This discovery could reshape our understanding of type Ia supernova progenitors and the dynamics of binary star systems.Meteorite Misidentified as Gold: A surprising tale of an Australian prospector who mistook a 17-kilogram meteorite for a gold nugget. This H5 ordinary chondrite, dating back to the solar system's birth, highlights the serendipitous treasures that can fall from the sky.For more cosmic updates, visit our website at astronomydaily.io. Join our community on social media by searching for #AstroDailyPod on Facebook, X, YouTubeMusic, TikTok, and our new Instagram account! Don't forget to subscribe to the podcast on Apple Podcasts, Spotify, iHeartRadio, or wherever you get your podcasts.Thank you for tuning in. This is Anna and Avery signing off. Until next time, keep looking up and exploring the wonders of our universe.✍️ Episode ReferencesHigh Impulse SL1 Rocket Development[High Impulse](https://www.highimpulse.com/)Atomic 6 Space Armor Technology[Atomic 6](https://www.atomic6.com/)Black Hole Research Insights[Goda University](https://www.godauniversity.edu/)White Dwarf Studies[Astrophysics Journal](https://www.astrophysicsjournal.com/)Meteorite Discovery Story[Geological Society](https://www.geologicalsociety.com/)Astronomy Daily[Astronomy Daily](http://www.astronomydaily.io/)Become a supporter of this podcast: https://www.spreaker.com/podcast/astronomy-daily-space-news-updates--5648921/support.Sponsor Details:Ensure your online privacy by using NordVPN. To get our special listener deal and save a lot of money, visit www.bitesz.com/nordvpn. You'll be glad you did!Become a supporter of Astronomy Daily by joining our Supporters Club. Commercial free episodes daily are only a click away... Click HereSponsor Details:Ensure your online privacy by using NordVPN. To get our special listener deal and save a lot of money, visit www.bitesz.com/nordvpn. You'll be glad you did!Become a supporter of Astronomy Daily by joining our Supporters Club. Commercial free episodes daily are only a click way... Click Here

The European Parliament has conducted its final vote, and now the bill moves to the Council of the European Union.View the full article here.Subscribe to the IMI Daily newsletter here. 

On the surface, life and business look good. You're checking all the boxes. But something still feels off. In this episode, Genea reveals why most entrepreneurs feel like they're living a "level 6 (ir lower) life" even when they've achieved success on paper.  The issue isn't your strategy, your work ethic, or your talent.  It's your decision-making mechanism … the invisible autopilot system that's been running your life since childhood. Genea walks you through:

A protective screen of spurious transcriptional activity enables each olfactory neuron to express exactly one out of hundreds of olfactory receptors.

The Mind-at-Large Project is a three-year, multidisciplinary initiative exploring consciousness and its role in reality. Mind-at-Large seeks to expand this paradigm - investigating the mind's presence across scales, from quantum systems and living organisms to ecosystems and the cosmos itself. This series examines ideas such as panpsychism, pantheism, idealism, 4E cognition, animism, perspectivism, and non-human intelligence, while also engaging with extraordinary phenomenologies found in psychedelic experiences, mystical states, and anomalous consciousness.TIMESTAMPS:(00:00) – Introduction: The Mind-at-Large Project – Consciousness Beyond the Brain(02:30) – Setting the Stage: Bridging Science, Philosophy & Mysticism(06:10) – What Does “Mind-at-Large” Mean? Context from Bergson, James & Whitehead(10:25) – Peter on Philosophy's Role: Expanding Mind Beyond Materialism(14:02) – Matt on Process Philosophy: Cosmos as a Living Mind(18:35) – Psychedelics, Panpsychism & the Renewal of Consciousness Studies(23:15) – The Crisis of Materialism: Why Science Needs a Broader Ontology(28:20) – Reconciling Science & Spirituality Without Dogma(33:40) – Whitehead's Influence: From Process to Participation(39:15) – Consciousness as Cosmos: The Participatory Universe(43:45) – Bergson's "Élan Vital" and the Evolution of Experience(47:52) – Peter on Nietzsche, Bergson & Psychedelic Metaphysics(53:00) – Matt on Cosmotheology: The Universe as an Ongoing Creation(58:24) – Ethics of Expanding Consciousness: Individual & Cosmic Implications(1:03:12) – Philosophy's Function Today: Meaning in an Age of Mechanism(1:07:40) – The Role of Psychedelics in Re-enchanting the World(1:13:02) – Toward an Integrative Science of Mind-at-Large(1:18:26) – Panpsychism vs. Idealism: Mapping the Metaphysical Terrain(1:23:58) – Matt on Whitehead's Process Metaphysics & Ecology of Mind(1:29:47) – Peter on Nietzsche's Eternal Return & Mind as Becoming(1:34:25) – The Future of Consciousness Studies: Interdisciplinary Frontiers(1:40:10) – Mind-at-Large Conferences: Mission, Vision & Collaboration(1:46:28) – Closing Reflections: Consciousness, Cosmos & Human MeaningEPISODE LINKS:- Mind-at-Large Project: https://mindatlargeproject.com- Peter's Website: https://www.philosopher.eu- Peter's YouTube: https://youtube.com/@Ontologistics- Peter's X: https://twitter.com/PeterSjostedtH- Peter's LinkedIn: https://uk.linkedin.com/in/dr-peter-sjöstedt-hughes-2b7a2927- Peter's Podcast: https://youtu.be/t6FZ5AB5998?si=RUNsQLyRMJQR9HXW- Peter's Lecture: https://www.youtube.com/watch?v=f4yCrqS0dCY- Matt's Website: https://footnotes2plato.com- Matt's YouTube: https://youtube.com/@footnotes2plato- Matt's Podcast: https://www.youtube.com/watch?v=9Vgskuk6Ef0- Matt's Lecture: https://youtu.be/XGulaiHDheY?si=bsZU-ohYTmhjTQJ6- Matt's X: https://x.com/ThouArtThat- Matt's LinkedIn: https://www.linkedin.com/in/matthewdavidsegallCONNECT:- Website: https://mindbodysolution.org- Podcast: https://creators.spotify.com/pod/show/mindbodysolution- YouTube: https://youtube.com/mindbodysolution- Twitter: https://twitter.com/drtevinnaidu- Facebook: https://facebook.com/drtevinnaidu - Instagram: https://instagram.com/drtevinnaidu- LinkedIn: https://linkedin.com/in/drtevinnaidu- Website: https://tevinnaidu.com=============================Disclaimer: The information provided on this channel is for educational purposes only. The content is shared in the spirit of open discourse and does not constitute, nor does it substitute, professional or medical advice. We do not accept any liability for any loss or damage incurred from you acting or not acting as a result of listening/watching any of our contents. You acknowledge that you use the information provided at your own risk. Listeners/viewers are advised to conduct their own research and consult with their own experts in the respective fields.

Featuring an interview with Dr Ghayas Issa, including the following topics: Mechanism of action and efficacy of menin inhibitors (0:00) Presentation and management of differentiation syndrome (13:31) Role of menin inhibitors in other cancers (18:19) Case: A woman in her mid 40s with KMT2A-rearranged acute myeloid leukemia (AML) after treatment for breast cancer (20:51) Mechanisms of resistance to menin inhibition in AML (26:53) Case: A woman in her early 70s with monocytic AML and multiple mutations including NPM1 experienced complete response with ziftomenib (32:31) Mechanism of action of menin inhibitors as differentiation agents (38:05) Similarities and differences between approved and investigational menin inhibitors under clinical development for the treatment of AML (45:55) Dual targeted therapy and other novel treatment approaches under clinical evaluation with menin inhibitors (51:25) Other investigational therapeutic strategies in AML (54:39) CME information and select publications

Wastewater isn't an endpoint—it's a decision point. On Wastewater Thursday, host Trace Blackmore, CWT sharpens the operator's toolkit with field-tested lessons: dose by mechanism, verify by sampling discipline, and use wastewater's fast feedback to protect quality, cost, and permits. Sampling discipline protects credibility Trace recounts an early-career moment when an inspector sampled the wrong location, triggering alarms. Immediate, methodical resampling—guided by logs and a clear process map—proved the system was in spec. The leadership takeaway: embed verification before escalation. Clear sampling points, time-stamped logs, and a rapid “reproduce the reading” drill turn uncertainty into clarity.  Mechanism over myth: coagulant control  In a new Detective H2O case, James McDonald explains why overfeeding coagulant collapses floc. When particles swing past neutral, like charges repel again and settling stalls. The fix is not “more chemistry,” but right-sizing dose to production and confirming with jar tests at the correct take-off point.  From discharge to resource  Greetings from past guests reinforce the shift under way. Arnaud Valleteau de Moulliac (Veolia Water Technology) frames wastewater as a local, decarbonized resource—with energy-positive plants and reuse as standard practice. Steve Russell (Kiewit) notes supply pressure will push even deeper recycling. Mark Lewis, CWT (Southeastern Laboratories) underscores wastewater's advantage: “If you treat it, you see it.”  Make wastewater a reliable, fast-feedback control loop—rooted in charge balance, sampling rigor, and reuse thinking.  Listen to the full conversation above. Explore related episodes below. Stay engaged, keep learning, and continue scaling up your knowledge!    Timestamps:  02:17 — Welcome to Wastewater Thursday and the IWW25 theme: “From foundations to futures.” 03:03 — Why wastewater is “the restart”: cleaning for reuse and sustainability. 04:24 — “Every drop counts from influent to effluent” — defining the professional mandate. 05:12 — Field story setup: jar testing with Trace's father; early lessons. 06:05 — Crisis call: bad regulatory number traced to wrong sampling location. 08:54 — Guest greeting: Arnaud Valleteau de Moulliac (Veolia) on energy-positive, reuse-driven futures. 10:25 — Guest greeting: Steve Russell (Kiewit) on permits, mass balances, and supply-driven recycling. 12:09 — Guest greeting: Mark Lewis, CWT (Southeastern Laboratories) on jar tests and product selection. 14:40 — Detective H2O: The case of too much of a good thing 20:17 — Mechanism lesson: charge neutralization window; like-charge repulsion returns when overdosed. 21:36 — Action: reduce dose; account for residence time; restore performance. 24:29 — IWW25 community prompt: post a safety-approved photo with wastewater equipment; use tags.   Connect with Mark Lewis   Phone: 704.322.5406   Email: MLewis@SELaboratories.com    Website: https://www.selaboratories.com/    LinkedIn: linkedin.com/in/mark-lewis-01a3b56    Connect with Steve Russell   Phone: 913.689.4533  Email: steve.russell@kiewit.com  Website: https://www.kiewit.com/  LinkedIn: https://www.linkedin.com/in/steve-russell-2b0a7960/    Connect with Arnaud Valleteau de Moulliac   Email: arnaud.valleteau@veolia.com Website: www.veoliawatertechnologies.com LinkedIn: linkedin.com/in/arnaud-valleteau-de-moulliac-9b85353a/   www.linkedin.com/company/veolia-water-technologies/    Links Mentioned  AWT (Association of Water Technologies)  Scaling UP! H2O Academy video courses  Submit a Show Idea  The Rising Tide Mastermind  031 The One with Mark Lewis  034 The Other One With Mark Lewis, CWT  112 The One Where Trace Is Interviewed By Mark Lewis  141 The One About Neglected Accounts  149 The One About Some of the Lesser-Used Technologies  382 Leading with Safety: How Veolia Embeds Health into Global Culture  396 Navigating Carbon Capture: Water Demands and Wastewater Solutions with Steve Russell  404 Eight Tips for Business Management: Part 1 – Essential Strategies  406 Eight Tips for Business Management: Part 2 – Essential Strategies 

Welcome to the Social-Engineer Podcast: The Doctor Is In Series – where we will discuss understandings and developments in the field of psychology.   In today's episode, Chris and Dr. Abbie explore the intriguing phenomena of dreams, the placebo effect, and déjà vu. They delve into the mysteries of why dreams can feel more emotionally intense than reality, how belief can trigger real physiological changes, and the perplexing sensation of déjà vu that leaves us questioning our memories. Through engaging discussions, they uncover what science knows and the many questions that remain unanswered about these fascinating topics. [Oct 6, 2025]   00:00 - Intro 00:54 - Dr. Abbie Maroño Intro 01:14 - Intro Links -          Social-Engineer.com - http://www.social-engineer.com/ -          Managed Voice Phishing - https://www.social-engineer.com/services/vishing-service/ -          Managed Email Phishing - https://www.social-engineer.com/services/se-phishing-service/ -          Adversarial Simulations - https://www.social-engineer.com/services/social-engineering-penetration-test/ -          Social-Engineer channel on SLACK - https://social-engineering-hq.slack.com/ssb -          CLUTCH - http://www.pro-rock.com/ -          innocentlivesfoundation.org - http://www.innocentlivesfoundation.org/                                 03:17 - The Topic of the Day: Dreams, Placebo and Deja Vu 04:11 - Why Do We Dream? 07:01 - Information Integration 09:36 - Second-Hand Emotion 11:41 - What We Don't Know 14:28 - Uploading Your Dreams 17:26 - The Placebo Effect 22:57 - Context Dependent 26:09 - Non-Responders 28:21 - Deja Vu 30:01 - The Smell Trigger 31:31 - The Emotional Aspect 34:43 - What's Your Sign? 35:44 - Wrap Up 35:59 - Next Month: Ambition    36:34 - Outro -          www.social-engineer.com -          www.innocentlivesfoundation.org   Find us online: -          LinkedIn: linkedin.com/in/dr-abbie-maroño-phd -          Instagram: @DoctorAbbieofficial -          LinkedIn: linkedin.com/in/christopherhadnagy     References: Barrett, D. (2001). The committee of sleep: How artists, scientists, and athletes use dreams for creative problem solving—and how you can too. Oneiroi Press.   de la Fuente-Fernández, R., Ruth, T. J., Sossi, V., Schulzer, M., Calne, D. B., & Stoessl, A. J. (2001). Expectation and dopamine release: Mechanism of the placebo effect in Parkinson's disease. Science, 293(5532), 1164–1166. https://doi.org/10.1126/science.1060937   Hobson, J. A. (2009). REM sleep and dreaming: Towards a theory of protoconsciousness. Nature Reviews Neuroscience, 10(11), 803–813. https://doi.org/10.1038/nrn2716 Hobson, J. A., & McCarley, R. W. (1977). The brain as a dream state generator: An activation-synthesis hypothesis of the dream process. Cognitive Psychology, 5(4), 448–502. https://doi.org/10.1016/0010-0285(77)90005-9   Platek, S. M., Critton, S. R., Myers, T. E., & Gallup, G. G. (2003). Contagious yawning: The role of self-awareness and mental state attribution. Cognitive Brain Research, 17(2), 223–227. https://doi.org/10.1016/S0926-6410(03)00109-5   Revonsuo, A. (2000). The reinterpretation of dreams: An evolutionary hypothesis of the function of dreaming. Consciousness and Cognition, 9(2), 210–218. https://doi.org/10.1006/ccog.2000.0422   Stickgold, R., & Walker, M. P. (2013). Sleep-dependent memory triage: Evolving generalization through selective processing. Trends in Cognitive Sciences, 17(10), 501–507. https://doi.org/10.1016/j.tics.2013.06.003   Voss, U., Holzmann, R., Tuin, I., & Hobson, J. A. (2009). Lucid dreaming: A state of consciousness with features of both waking and non-lucid dreaming. Sleep, 32(9), 1191–1200. https://doi.org/10.1093/sleep/32.9.1191   Wager, T. D., Scott, D. J., & Zubieta, J.-K. (2007). Placebo effects on human μ-opioid activity during pain. NeuroImage, 35(1), 253–264. https://doi.org/10.1016/j.neuroimage.2006.11.026

This week we're joined by Adele Houghton of the Harvard School of Public Health and Carlos Castillo-Salgado of the Johns Hopkins Bloomberg School of Public Health to discuss their new book Architectural Epidemiology: Architecture as a Mechanism for Designing a Healthier, More Sustainable, and Resilient World. We chat about how to connect the social and architectural determinants of health before projects get off the ground in order to create more healthy neighborhoods. +++ Get the show ad free on Patreon! Follow us on Bluesky, Threads, Instagram, YouTube, Flickr, Substack ... @theoverheadwire Follow us on Mastadon theoverheadwire@sfba.social Support the show on Patreon http://patreon.com/theoverheadwire Buy books on our Bookshop.org Affiliate site!  And get our Cars are Cholesterol shirt at Tee-Public! And everything else at http://theoverheadwire.com

SUMMARY In this episode of Vibe Science, Ryan Alford interviews Dr. Paramesh Gopi, co-founder of Sound Health. Dr. Paramesh Gopi shares his journey from tech entrepreneur to doctor, and discusses the development of the Sono Band—a wearable device using AI-powered, personalized sound and vibration therapy to clear nasal congestion and improve sleep. The episode covers clinical results, FDA clearance, and new research on sleep improvement, as well as upcoming products and applications in airway health. Listeners learn how innovative technology is transforming wellness through better breathing, sleep, and overall performance.   TAKEAWAYS Personal health journey of Dr. Paramesh Gopi and its impact on his work. Development of Sound Health and the Sono Band wearable device. Use of AI and machine learning to create personalized sound and vibration therapy. Mechanism of action: how sound and vibration clear nasal congestion. Clinical evidence supporting the effectiveness of the Sono Band. FDA clearance process and clinical trials for the device. Broader applications of the technology for sleep improvement and overall wellness. Future product developments, including a focus on sleep and airway health. Importance of non-invasive, drug-free alternatives for treating nasal congestion and related issues. Interconnectedness of breathing, sleeping, and overall health performance. This episode is sponsored by: Warrior Salt Electrolyte Powder – Hydrate & Reenergize Naturally Experience Warrior Salt's all-natural electrolyte powder for optimal hydration and performance. Boost energy, prevent cramps, and stay hydrated. Order Now!  

Project Sync / Status Update Summary Podcast Episode Overview The host discussed Transcutaneous Electrical Nerve Stimulation (TENS) as a recurring pain board topic and reviewed mechanisms, efficacy, and clinical considerations. Emphasis that TENS appears on pain boards annually and is a foundational topic from early podcast episodes. Board Prep and NRAP Community at PainExam.com or NRAPpain.org ABA ABPM ABIPP FIPP Pain Management Board prep, Question Banks, and Virtual Pain Fellowship Educational Offerings and Events Training and Courses: Monthly ultrasound courses in New York and upcoming courses in Detroit covering ultrasound-guided regional anesthesia and chronic pain. Ultrasound Guided Acute and Chronic Pain course in November near Hollywood/Fort Lauderdale with venue pending confirmation. Multiple instructors to offer diverse perspectives; registration via the CME calendar at nrappain.org. Conferences and Teaching: New York–New Jersey Pain Conference in November (hosted by Soudir Duwan). ISPN conference in London next week, with ultrasound teaching participation by the host. Community and Coaching: Private coaching and shadowing opportunities available; contact via newsletter replies. Access to the NRAP community forum upon signup at nrappain.org for discussions on neuromodulation, regional anesthesia, and pain. TENS: Mechanisms and Parameters Device and Parameters: TENS delivers adjustable pulse frequency and intensity; configurations include low (50–100+ Hz), and mixed frequencies. Mechanisms of Analgesia: Activation of large-diameter, non-noxious A-beta afferent fibers in the periphery, driving descending inhibitory pathways and reducing hyperalgesia. Board-relevant point: selective activation of A-beta fibers is frequently tested. Central effects: Reduces central excitability and nociceptive dorsal horn neuron activity in uninjured and injured models. Frequency-dependent opioid receptor mediation: High-frequency analgesia blocked by delta receptor antagonists. Low-frequency analgesia blocked by mu receptor antagonists (spinal cord and rostral ventral medulla). Additional receptor involvement: muscarinic M1/M3, GABA-A, and cannabinoid (CB1) receptors; blockade reduces or prevents TENS analgesia depending on frequency. Peripheral effects: High-frequency TENS reduces injury-related increases in substance P in DRG neurons. Blockade of peripheral opioid and CB1 receptors can prevent analgesia from both low- and high-frequency TENS. Clinical dosing considerations: Adequate dosing (timing, frequency of use, intensity achieving strong but non-painful paresthesia) influences efficacy. Analgesia has rapid onset/offset and may require repeated administration throughout the day for sustained relief. Evidence and Efficacy Summary Systematic Review Findings: Cochrane umbrella review of 9 systematic reviews (51 trials; n=2,895) comparing active TENS with sham/usual care found uncertain efficacy due to: Very low-quality evidence (risk of bias, small samples, methodological limitations). Inconsistent adverse event reporting. Heterogeneity in TENS parameters and comparators. Authors note uncertainty may be confounded by inadequate dosing not being an inclusion metric. Practical Interpretation: TENS is inexpensive, low-risk, self-administered, and titratable; commonly used by patients and physical therapists. Clinical experience suggests potential adjunctive benefit for acute pain, but systematic reviews are conflicting; more rigorous studies are needed. For board preparation, the critical takeaway is A-beta fiber activation. Key Takeaways for Board Prep TENS targets large-diameter non-noxious A-beta afferents to reduce nociceptive signaling. High-frequency TENS: analgesia mediated via delta opioid receptors; blocked by delta antagonists. Low-frequency TENS: analgesia mediated via mu opioid receptors; blocked by mu antagonists in spinal cord and RVM. Additional receptor systems influencing TENS efficacy include muscarinic (M1/M3), GABA-A, and CB1. Action Items Review TENS mechanisms with emphasis on A-beta fiber activation for board prep. Verify and publish final venue details for the November Florida ultrasound course. Share registration links and schedules for Detroit and New York ultrasound and chronic pain courses via CME calendar. Prepare teaching materials for ISPN London ultrasound sessions next week. Update board prep resources on painexam.com and nrappain.org with current TENS evidence and dosing guidance. Promote NRAP community forum access and private coaching/shadowing opportunities through the newsletter.   David Rosenblum, MD, currently serves as the Director of Pain Management at Maimonides Medical Center and AABP Integrative Pain Care.  As a member of the Department of Anesthesiology, he is involved in teaching, research, CME activities, and was key faculty in developing the anesthesiology residency's regional anesthesia block rotation, as well as institutional wide acute and chronic pain management protocols to ensure safe and effective pain management. He currently is a managing partner in a multi-physician private pain practice, AABP Integrative Pain Care, located in Brooklyn, NY. He is one of the earliest interventional pain physicians to integrate ultrasound guidance to improve the safety and accuracy of interventional pain procedures. Patients can go to www.AABPpain.com or call 718 436 7246 Awards New York Magazine: Top Doctors: 2016, 2017, 2018, 2021, 2022, 2023, 2024, 2025 Schneps Media: 2015, 2016, 2017, 2019, 2020 Top Doctors New York Metro Area (digital guide): 2016, 2017, 2018, 2019, 2020, 2021, 2022, 2023 2025 Schneps Media - Brooklyn Courier Life: 2021, 2022, 2023 References  Johnson M. Transcutaneous Electrical Nerve Stimulation: Mechanisms, Clinical Application and Evidence. Rev Pain. 2007 Aug;1(1):7-11. doi: 10.1177/204946370700100103. PMID: 26526976; PMCID: PMC4589923.   Vance, C.G.T.; Dailey, D.L.; Chimenti, R.L.; Van Gorp, B.J.; Crofford, L.J.; Sluka, K.A. Using TENS for Pain Control: Update on the State of the Evidence. Medicina 2022, 58, 1332. https://doi.org/10.3390/medicina58101332 #painnyc #painbrooklyn #prpbrooklyn #prpspine #regionalanesthsia #pccwindsor #paincareclinicswindsor #painwindsorontario #paindocwindsorontarior #paincareclinics #prpwindsorontario #prp 

Project Sync / Status Update Summary Podcast Episode Overview The host discussed Transcutaneous Electrical Nerve Stimulation (TENS) as a recurring pain board topic and reviewed mechanisms, efficacy, and clinical considerations. Emphasis that TENS appears on pain boards annually and is a foundational topic from early podcast episodes. Board Prep and NRAP Community at PainExam.com or NRAPpain.org ABA ABPM ABIPP FIPP Pain Management Board prep, Question Banks, and Virtual Pain Fellowship Educational Offerings and Events Training and Courses: Monthly ultrasound courses in New York and upcoming courses in Detroit covering ultrasound-guided regional anesthesia and chronic pain. Ultrasound Guided Acute and Chronic Pain course in November near Hollywood/Fort Lauderdale with venue pending confirmation. Multiple instructors to offer diverse perspectives; registration via the CME calendar at nrappain.org. Conferences and Teaching: New York–New Jersey Pain Conference in November (hosted by Soudir Duwan). ISPN conference in London next week, with ultrasound teaching participation by the host. Community and Coaching: Private coaching and shadowing opportunities available; contact via newsletter replies. Access to the NRAP community forum upon signup at nrappain.org for discussions on neuromodulation, regional anesthesia, and pain. TENS: Mechanisms and Parameters Device and Parameters: TENS delivers adjustable pulse frequency and intensity; configurations include low (50–100+ Hz), and mixed frequencies. Mechanisms of Analgesia: Activation of large-diameter, non-noxious A-beta afferent fibers in the periphery, driving descending inhibitory pathways and reducing hyperalgesia. Board-relevant point: selective activation of A-beta fibers is frequently tested. Central effects: Reduces central excitability and nociceptive dorsal horn neuron activity in uninjured and injured models. Frequency-dependent opioid receptor mediation: High-frequency analgesia blocked by delta receptor antagonists. Low-frequency analgesia blocked by mu receptor antagonists (spinal cord and rostral ventral medulla). Additional receptor involvement: muscarinic M1/M3, GABA-A, and cannabinoid (CB1) receptors; blockade reduces or prevents TENS analgesia depending on frequency. Peripheral effects: High-frequency TENS reduces injury-related increases in substance P in DRG neurons. Blockade of peripheral opioid and CB1 receptors can prevent analgesia from both low- and high-frequency TENS. Clinical dosing considerations: Adequate dosing (timing, frequency of use, intensity achieving strong but non-painful paresthesia) influences efficacy. Analgesia has rapid onset/offset and may require repeated administration throughout the day for sustained relief. Evidence and Efficacy Summary Practical Interpretation: TENS is inexpensive, low-risk, self-administered, and titratable; commonly used by patients and physical therapists. Clinical experience suggests potential adjunctive benefit for acute pain, but systematic reviews are conflicting; more rigorous studies are needed. For board preparation, the critical takeaway is A-beta fiber activation. Key Takeaways for Board Prep TENS targets large-diameter non-noxious A-beta afferents to reduce nociceptive signaling. High-frequency TENS: analgesia mediated via delta opioid receptors; blocked by delta antagonists. Low-frequency TENS: analgesia mediated via mu opioid receptors; blocked by mu antagonists in spinal cord and RVM. Additional receptor systems influencing TENS efficacy include muscarinic (M1/M3), GABA-A, and CB1. Action Items Review TENS mechanisms with emphasis on A-beta fiber activation for board prep. Verify and publish final venue details for the November Florida ultrasound course. Share registration links and schedules for Detroit and New York ultrasound and chronic pain courses via CME calendar. Prepare teaching materials for ISPN London ultrasound sessions next week. Update board prep resources on painexam.com and nrappain.org with current TENS evidence and dosing guidance. Promote NRAP community forum access and private coaching/shadowing opportunities through the newsletter.   David Rosenblum, MD, currently serves as the Director of Pain Management at Maimonides Medical Center and AABP Integrative Pain Care.  As a member of the Department of Anesthesiology, he is involved in teaching, research, CME activities, and was key faculty in developing the anesthesiology residency's regional anesthesia block rotation, as well as institutional wide acute and chronic pain management protocols to ensure safe and effective pain management. He currently is a managing partner in a multi-physician private pain practice, AABP Integrative Pain Care, located in Brooklyn, NY. He is one of the earliest interventional pain physicians to integrate ultrasound guidance to improve the safety and accuracy of interventional pain procedures. Patients can go to www.AABPpain.com or call 718 436 7246 Awards New York Magazine: Top Doctors: 2016, 2017, 2018, 2021, 2022, 2023, 2024, 2025 Schneps Media: 2015, 2016, 2017, 2019, 2020 Top Doctors New York Metro Area (digital guide): 2016, 2017, 2018, 2019, 2020, 2021, 2022, 2023 2025 Schneps Media - Brooklyn Courier Life: 2021, 2022, 2023 References  Johnson M. Transcutaneous Electrical Nerve Stimulation: Mechanisms, Clinical Application and Evidence. Rev Pain. 2007 Aug;1(1):7-11. doi: 10.1177/204946370700100103. PMID: 26526976; PMCID: PMC4589923.   Vance, C.G.T.; Dailey, D.L.; Chimenti, R.L.; Van Gorp, B.J.; Crofford, L.J.; Sluka, K.A. Using TENS for Pain Control: Update on the State of the Evidence. Medicina 2022, 58, 1332. https://doi.org/10.3390/medicina58101332 #painnyc #painbrooklyn #prpbrooklyn #prpspine #regionalanesthsia #pccwindsor #paincareclinicswindsor #painwindsorontario #paindocwindsorontarior #paincareclinics #prpwindsorontario #prp 

Effects of Social Isolation and Loneliness on the Heart   Guest: Amir Lerman, M.D. Host: Stephen L. Kopecky, M.D.   Social isolation and loneliness are common, mainly in the elderly, and are regarded as major cardiovascular risk factors. The factors are associated with an increase in cardiovascular events and mortality. Additionally, social isolation and loneliness are associated with increased systemic inflammation and progression of atherosclerosis   Topics Discussed: How do you identify social isolation? Mechanism of social isolation and loneliness on CV health Prevalences and risk of social isolation and loneliness Findings of a recent study from Mayo Clinic Case story: the Roseto effect Potential therapy    Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode.   Podcast episode transcript found here.

What if context—patient beliefs, provider expectations, and the therapeutic relationship—drives a meaningful share of spinal manipulation outcomes? In this HANDS ON HANDS OFF episode, we break down a single-arm intervention study funded by the Paris Family Foundation via the Foundation for OMPT, why the current mechanisms model zeroes in on the “context zone,” and how to practically weave guidelines + shared decision-making into outpatient practice.Top takeawaysOutcomes vary—and context might be part of the mechanismStudy design links individual providers ↔ individual patients for cleaner signalsImplementation: use shared decision-making to operationalize guidelinesCareer notes: pick mentors early, build long-term collaborators, include patient partners

rWotD Episode 3069: Castes in India: Their Mechanism, Genesis and Development Welcome to random Wiki of the Day, your journey through Wikipedia's vast and varied content, one random article at a time.The random article for Sunday, 28 September 2025, is Castes in India: Their Mechanism, Genesis and Development.Castes in India: Their Mechanism, Genesis and Development was a paper read by B. R. Ambedkar at an anthropological seminar of Alexander Goldenweiser in New York on 9 May 1916. It was later published in volume XLVI of Indian Antiquary in May 1917. In the same year, Ambedkar was awarded a PhD degree by Columbia University on this topic. In 1979, the Education Department of the Government of Maharashtra (Bombay) published this article in the collection of Ambedkar's writings and speeches Volume 1; later, it was translated in many languages.In the paper, Ambedkar made a presentation a social phenomenon that emerged from the strategy of the Brahmins who adopted a strictly endogamous matrimonial regime, leading the other groups to do the same in order to emulate this self-proclaimed elite. He said that "the superposition of endogamy on exogamy means the creation of caste".This recording reflects the Wikipedia text as of 00:15 UTC on Sunday, 28 September 2025.For the full current version of the article, see Castes in India: Their Mechanism, Genesis and Development on Wikipedia.This podcast uses content from Wikipedia under the Creative Commons Attribution-ShareAlike License.Visit our archives at wikioftheday.com and subscribe to stay updated on new episodes.Follow us on Bluesky at @wikioftheday.com.Also check out Curmudgeon's Corner, a current events podcast.Until next time, I'm standard Kendra.

Shai Wyborski is one of the three co-authors of the GHOSTDAG paper, and a man who takes pride in his independent thinking and divergent approach to research. As a PhD in quantum cryptography, he's got lots of knowledge to share. But by virtue of his involvement in Bitcoin and Kaspa, he's got stories to tell too. What does the future of Proof of Work look like? Let's find out! Time stamps: 00:01:09 - Welcoming Shai Wyborski 00:01:28 - Dig into GhostDAG; most interesting PoW scaling tech. 00:04:44 - Shai's BTC opinions over time 00:05:21 - How Shai spent BTC on "creativity fuel" (undisclosed). 00:06:31 - Disenchantment: Steam drops BTC (congestion/volatility); SegWit "tyranny" births BCH. 00:10:47 - Rejects SoV; BTC as "decentralized vault" for eternal data archiving. 00:15:44 - BTC probs: Low TPS; LN fails. 00:16:15 - Kaspa suite: Beyond TPS/confirmations. 00:16:59 - Tradeoff: High throughput → no audit; pruning for 10-30yr trust. 00:18:40 - GhostDAG multi-ledger: Parallel processing, flexible tx order. 00:19:45 - Miners: Partial info cuts selfish mining/MEV. 00:20:42 - Enables auctions/oracles (Elliot Mabe block-voting). 00:21:40 - Debunks PoW myths: BTC artifacts (congestion for fees). 00:22:15 - Kaspa: Paradigm shift proof; lessons from protocols. 00:23:24 - Flaw: Fast emission + fair launch = whale buyout. 00:23:49 - Fair ≠ community; coercion w/o social contract. 00:25:10 - Whales fund → control; monetary world nature. 00:27:46 - Balance: Incentives, explicit contracts. 00:30:31 - Mining phases: CPU/GPU/ASIC stages; ultra-ASIC decen lock. 00:32:22 - ASIC-friendly: Cheap/low-power scale. 00:32:47 - Emission: Heavy early; ASICs 80-90% pre-retail. 00:34:29 - Full supply lifetime; tail short?00:35:28 - BTC emission extend 2-4x for social good. 00:37:27 - Kaspa whales: 3 hold 6% ($100M), foundation collusion. 00:38:27 - Kaspa emission: 60% in 1.5yrs emulates BTC adjusted for fast adoption. 00:41:16 - Guitar jam & sponsors.SideShift.ai: KYC-free swaps. NoOnes.com: P2P global south, "lions" mission. Bitcoin.com News: global views. LayerTwo Labs: Drivechains, ETH/Zcash sides. 00:46:49 - Kaspa drivechain?; WBTC custody risks. 00:48:33 - Citrea: ZK-rollup BTC DeFi. 00:49:27 - Alts: Quai grant, Kadena parallels. 00:50:47 - Parallel sec dilution. 00:52:03 - Quai: Selfish mining fixes, Monero 28% vuln. 00:53:01 - Monero RandomX ASIC-hostility. 00:54:02 - PoW specialized non-wasteful. 01:00:00 - Myths: Scalable, non-congested, decentralization. 01:15:00 - Casino stifles ingenuity; hype vs depth (IOTA rush). 01:30:00 - Funding: Retail quick vs VC long (Mobileye 20yr $80B). 01:45:00 - Game theory: Mechanism design incentives. 02:00:00 - Kaspa risks: Whale control, docs issues. 07:00:00 - Music: Beatles Sgt. Pepper post-Pet Sounds. 07:15:00 - McCartney bass; prog Floyd/Crimson.07:30:00 - Pet Sounds "God Only Knows" acapella. 07:43:02 - Pop→exp; Helter Skelter metal. 07:45:36 - Metal thrash/extreme; stoner Pantheon I. 07:47:41 - HS Pantera/prog/funk.07:49:51 - Concerts: Aristocrats, AC/DC; Dylan regret. 07:52:39 - Misses: Jethro Tull/Motörhead; Bon Jovi meh. 07:55:16 - Grunge: Nirvana In Utero, Soundgarden. 07:58:11 - Smashing Pumpkins trilogy; Corgan drama. 08:00:00 - Timeless tees; Doors sloppy; Zep Moby Dick. 08:02:40 - Zappa Inca Roads/Stink-Foot. 08:07:19 - AI scans/drones; govt bans. 08:12:08 - Radical: Vault, SoV, ultra-ASIC. 08:14:02 - PoW scalable/non-wasteful.08:15:00 - Fair vs community; casino timing punish. 08:17:40 - Narratives over fundamentals; retail vs VC. 08:21:07 - Record 8h21m+; ramble praise. 08:21:50 - Q&A: Kaspa 10yr alive, adapt. 08:22:24 - Beatles Kaspa? Pruning no. 08:23:44 - Game theory mechanism design. 08:26:09 - Work: Consulting, patents, Tectonic quantum.08:29:23 - Quai edu grant, freelance. 08:31:17 - KAS +3% pump; past dumps. 08:31:58 - Quai minor pump; negative effects. 08:33:34 - First interview 0.15→0.5¢; 13 KAS dons. 08:34:21 - Jam: Theme rock, lag. 08:38:07 8h39m record! Sponsors recap. 08:40:00 - Next interview with Val Venis on Monero/WWF; banter.

Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Podcast: https://hunterwilliamspodcast.buzzsprout.com/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/In this video, I break down ATX-304 (also known as OS-01 or OS-03) — a powerful small molecule AMPK activator being studied for fat loss, metabolic health, and longevity. If you've heard ATX-304 described as “exercise in a capsule,” you'll see why after going through the research, mechanisms, human trials, and potential applications.I also share how ATX-304 works differently than GLP-1s, why it preserves muscle while supporting fat loss, and what the future may hold for this compound in anti-aging medicine.

In today's episode, we will conclude Chapter 5 on the Mechanism of Subluxation by discussing Compensation.  This was a revolutionary idea in Dr Gonstead's time, and the Gonstead system is still one of the only technique systems to address the presence of compensation.  This episode is crucial for learning how to distinguish between subluxation and compensation. 

Failure Mechanism Awareness Abstract Kirk and Fred discuss the many different failure mechanisms and the need for understanding the failure mechanisms and causes of failures. Key Points Join Kirk and Fred as they discuss why it is necessary to have an understanding of material science and the physics of failure mechanisms to do a thorough […] The post SOR 1107 Failure Mechanism Awareness appeared first on Accendo Reliability.

Send us a textIn today's episode of PTs Snacks podcast, hosted by Kasey, we dive into the intricacies of high ankle sprains, also known as syndesmotic ankle sprains. We'll explore the relevant anatomy, common mechanisms of injury, diagnostic techniques, and treatment strategies. Kasey also highlights the importance of distinguishing high ankle sprains from other types of ankle injuries and discusses both non-surgical and surgical management approaches. Whether you're a seasoned physical therapist or a student, this episode is packed with valuable insights to enhance your clinical practice.00:00 Introduction to PTs Snacks Podcast00:19 Understanding High Ankle Sprains00:56 Anatomy Review: Syndesmotic Ligaments03:43 Mechanism of Injury05:29 Clinical Presentation and Diagnosis06:43 Stress Tests for High Ankle Sprains08:29 Imaging and Differential Diagnoses09:30 Treatment and Rehabilitation Stages11:43 Prognosis and Final Thoughts12:19 Special Offers and ConclusionGo to PT Final Exam using this link to access great studying options to conquer the NPTE!Support the showStay Connected! Make sure to hit follow now so you don't miss an episode! Got questions? Email me at ptsnackspodcast@gmail.com or leave feedback HERE. You can also join the email list HERE Need CEUs Fast?Time and resources short? Medbridge has you covered: Get over $100 off a subscription with code PTSNACKSPODCAST: Medbridge Students: Save $75 off a student subscription with code PTSNACKSPODCASTSTUDENT—a full year of unlimited access for less! Prepping for the NPTE? Get all the study tools you need to master it at PT Final Exam. Use code PTSnacks at checkout to get a discount! Want to Support the Show?Help me keep creating free content by: Sharing the podcast with someone who'd benefit. Contributing directly via the link...

There's a new development project planned for the intersection of Holmes and Pleasant Grove in Southwest Lansing. This project is unique as it provides a creative investment opportunity for citizens. Joining Chris to share the vision and the strategy for the Holmes & Pleasant Grove project are members of the Lansing Growth Fund, Brent Forsberg and Chris Miller!

Show host Gene Tunny breaks down why price controls are one of the most consistently failed economic policies. Using vivid historical examples from the 1970s US, the Soviet Union's command economy, and Venezuela's toilet paper crisis, he illustrates how interfering with the price mechanism leads to shortages, inefficiency, and unintended consequences. Gene would love to hear your thoughts on this episode. You can email him via contact@economicsexplored.com.TimestampsIntroduction to the Podcast and Episode Theme (0:00)Price Controls and Their Economic Implications (2:47)President Nixon's Wage and Price Controls (8:53)The Soviet Union's Central Planning System (18:20)Economic Inefficiency in the Soviet Steel Industry (29:24)Venezuela's Toilet Paper Crisis (31:57)TakeawaysPrice controls disrupt vital economic signals, leading to misallocation of resources and market inefficiency.Nixon's wage and price freeze in the 1970s led to empty supermarket shelves, black markets, and farmers slaughtering livestock to cut their losses.Soviet central planning failed due to the absence of price signals, leading to constant shortages—even of basic goods like meat and bread.Venezuela's price caps on essentials like toilet paper created massive shortages and forced the government to import millions of rolls.The price mechanism acts as a societal dashboard, helping balance supply and demand more efficiently than central planning or rationing.Links relevant to the conversationBen Bernanke's book – 21st Century Monetary Policyhttps://www.amazon.com.au/21st-Century-Monetary-Policy-Inflation/dp/1324020466BBC News Article on Venezuela's Toilet Paper Crisis: "Venezuela aims to end toilet paper shortage"https://www.bbc.com/news/business-22621833Bread and Autocracy: Food, Politics, and Security in Putin's Russiahttps://www.amazon.com.au/Bread-Autocracy-Politics-Security-Putins/dp/019768436XStephen Kotkin – Armageddon Averted: The Soviet Collapse 1970–2000https://www.amazon.com.au/Armageddon-Averted-Soviet-Collapse-1970-2000/dp/0195368630Friedrich Hayek – “The Use of Knowledge in Society”https://www.econlib.org/library/Essays/hykKnw.htmlLumo Coffee promotion10% of Lumo Coffee's Seriously Healthy Organic Coffee.Website: https://www.lumocoffee.com/10EXPLOREDPromo code: 10EXPLORED 

Joe's Premium Subscription: www.standardgrain.comGrain Markets and Other Stuff Links-Apple PodcastsSpotifyTikTokYouTubeFutures and options trading involves risk of loss and is not suitable for everyone.0:00 Ag Economy6:57 Soybean Hit Piece9:58 SREs11:15 Grain Standards Act12:13 Cattle Selloff14:03 BLS Data (Jobs)

On today's episode: A common drug taken for heart conditions might not be as useful as we thought. How much energy does it take to get ChatGPT to help cook dinner tonight? All that and more today on All Around Science...RESOURCES https://www.sciencedaily.com/releases/2025/08/250831010539.htm What is a beta blocker? Mechanism of action. How beta blockers help the heart to work.Explained: Generative AI's environmental impact | MIT NewsAI's Growing Carbon FootprintCREDITS:Writing - Bobby Frankenberger & Maura ArmstrongBooking - September McCrady THEME MUSIC by Andrew Allenhttps://twitter.com/KEYSwithSOULhttp://andrewallenmusic.com Hosted on Acast. See acast.com/privacy for more information.

In today's episode, we begin our exploration of Chapter 5 on the Mechanism of Vertebral Subluxation.   We will begin by looking at the normal structure and function of the intervertebral disc and how it works in the ideal situation.  

John Batchelor 09-03 segment 15.mp3 Guest: Janatyn Sayeh from the Foundation for Defense of Democracies. Iran's Nuclear Dilemma and Regional Threats Janatyn Sayeh discusses the looming snapback mechanism of the 2015 JCPOA, which could reinstate UN sanctions on Iran if it fails to comply with demands. Iran's non-compliance has its currency hitting new lows, yet Tehran threatens regional war and exiting the NPT if sanctions return. Sayeh notes Iran seeks rearmament, primarily from China, with Belarus and North Korea acting as potential intermediaries for Russian weapons. 1852 TEHRAN

We get deep with the Wistful Bard himself Ray Flanagan as he shares the lessons and perspectives he's gained over 11 years as a full-time musician.Ray is deeply woven into Cleveland's music community. Catch him hosting jam nights every Tuesday at Mercury Music Lounge, or see his collaboration sets the last Monday of the month at The Winchester.His new album "My Mind is Burning Up" drops next spring, but you can get early access by DMing him for a private link. In the meantime, dive into his extensive discography on all streaming platforms. THANK YOU RAY.SONGS PERFORMED:Someone Else's ShoesI Love the NighttimeAshesWe're DoomedSimple Stuff I GuessPerformance mixed/mastered by Jake ConderCONNECT WITH RAY:https://www.instagram.com/rayaflanagan/https://rayflanagan.bandcamp.com/music----...if you have a sec - please leave us a rating/ review on Apple/ Spotify!Apple: https://podcasts.apple.com/us/podcast/locle-grown/id1619510885Spotify: https://open.spotify.com/show/6OpyraRZDUqf6h8ZKq8KE3?si=75f15ec563714a6cApply to be a guest: https://www.loclegrown.com/past-guests-and-how-to-apply Circle K is a proud sponsor of LoCLE Grown! Download the Inner Circle App today to get .25 cents per gallon off your first 5 fill ups and 5 free drinks! Learn more here: https://www.circlek.com/inner-circleCircle K Inner Circle iPhone App: https://apps.apple.com/us/app/circle-k/id1592397814Circle K Inner Circle  Google Play App: https://play.google.com/store/apps/details?id=com.circlek.gmap.na&hl=en&gl=US&pli=1

Welcome to PsychEd, the psychiatry podcast for medical learners, by medical learners. This episode covers exercise as a treatment for depression. Our guest for this episode is Dr. Nicholas Fabiano, a third-year psychiatry resident at the University of Ottawa. His research focuses on the overlap between mental and physical health, particularly lifestyle measures that can be used to improve mental health, including exercise, diet, and sleep.The learning objectives for this episode are as follows:Understand the evidence supporting the antidepressant effects of exercise Explore the mechanisms underlying the benefits of exerciseLearn how to prescribe exercise as a treatment for depressionIdentify the risks and caveats of prescribing exercise for depressionGuest: Dr. Nicholas Fabiano (PGY3)Hosts: Dr. Wendy MacMillan-Wang (PGY4) and Dr. Angad Singh (PGY1)Audio Editing: Dr. Angad Singh (PGY1)Timestamps:(2:55) Origins of the interest in exercise(6:22) Evidence of antidepressant effects(14:05) Considerations in special populations(18:00) Overlap of mental and physical health(20:37) Mechanism of action(26:18) Exercise prescription(33:10) Exercise as addiction and self-harm(36:42) Counselling and mitigating harm(39:30) Combining with other lifestyle interventions(41:41) Evidence for other mental illnessesReferences:Fabiano N, Gupta A, Fiedorowicz JG, Firth J, Stubbs B, Vancampfort D, Schuch FB, Carr LJ, Solmi M. The effect of exercise on suicidal ideation and behaviors: A systematic review and meta-analysis of randomized controlled trials. Journal of affective disorders. 2023 Jun 1;330:355-66.Fabiano, N., Puder, D., & Stubbs, B. (2024). The evidence is clear, exercise is not better than antidepressants or therapy: it is crucial to communicate science honestly. Journal of Physical Activity and Health, 1(aop), 1-2.Heissel, A., Heinen, D., Brokmeier, L. L., Skarabis, N., Kangas, M., Vancampfort, D., ... & Schuch, F. (2023). Exercise as medicine for depressive symptoms? A systematic review and meta-analysis with meta-regression. British journal of sports medicine, 57(16), 1049-1057.Hird, E. J., Slanina-Davies, A., Lewis, G., Hamer, M., & Roiser, J. P. (2024). From movement to motivation: a proposed framework to understand the antidepressant effect of exercise. Translational Psychiatry, 14(1), 273.Verhoeven, J. E., Han, L. K., Lever-van Milligen, B. A., Hu, M. X., Révész, D., Hoogendoorn, A. W., ... & Penninx, B. W. (2023). Antidepressants or running therapy: Comparing effects on mental and physical health in patients with depression and anxiety disorders. Journal of affective disorders, 329, 19-29.For more PsychEd, follow us on Instagram (@psyched.podcast),  Facebook (PsychEd Podcast), X (@psychedpodcast), and Bluesky (@psychedpodcast.bsky.social‬). You can email us at psychedpodcast@gmail.com and visit our website at psychedpodcast.org.

In this episode, Dr. Jockers takes a deep dive into the shocking truth about Ozempic and other GLP-1 weight loss drugs. You'll hear how these medications actually work in the body, why they cause rapid weight loss for some, and what doctors often leave out about their risks. The discussion is packed with insights you won't want to miss.   You'll also learn about the real side effects—ranging from digestive distress to more dangerous issues like thyroid cancer and kidney failure—that affect nearly one in five people taking these drugs. Dr. Jockers breaks down the science in plain language so you can make informed choices.   And if you're wondering whether there's a safer way to get the same results, you'll discover how protein, fiber, and healthy fats can mimic the appetite-regulating effects of Ozempic. These lifestyle strategies not only reduce cravings but also improve long-term health without the side effects.     In This Episode:  00:00 Introduction to Weight Loss Study 00:27 Welcome and Episode Overview 01:00 Exploring GLP-1 Agonists 03:51 Deep Dive into Weight Loss Medications 04:33 Mechanism of GLP-1 Drugs 09:21 Clinical Research Findings 12:30 Side Effects and Risks 14:08 Natural Alternatives to Medications 17:53 Conclusion and Final Thoughts     Are swollen legs or ankles slowing you down? Discover the power of Lymph System Support by Pure Health Research. Crafted with natural ingredients like dandelion extract, burdock root, and bromelain, this formula unclogs your lymphatic system, reducing swelling and supporting a healthy inflammatory response.   As a special offer, try Lymph System Support risk-free today and receive a complimentary bottle of curcumin extract. Visit GetLymphHelp.com/jockers to claim yours now. Say hello to renewed vitality and goodbye to discomfort!   Hair loss isn't just about age—it's about hair follicles getting stuck. AnaGain Nu by Purality Health uses a pea sprout extract clinically shown to reactivate follicles and boost regrowth. With their micelle liposomal delivery, your body absorbs it fast and effectively. Try it risk-free with a 180-day money-back guarantee and get a buy-one-get-one-free deal at RenewYourHair.com/DRJ.     “Ozempic lowers blood sugar, but it may also raise your risk of thyroid cancer, pancreatitis, and kidney failure.”  ~ Dr. Jockers   Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio   Resources: GetLymphHelp.com/jockers Visit https://renewyourhair.com/drj   Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/ 

What if telepathy isn't fantasy, but an undiscovered frontier of biophysics? In this conversation, Helené Wahbeh of the Institute of Noetic Sciences joins us to explore how mind-to-mind communication could be studied through neuroscience, quantum theory, and consciousness research. We're not obsessed with whether it's real — we're asking how it would work if it were. A tightrope the edge of what's known, where psi phenomena meets mechanism and physics.PATREON https://www.patreon.com/c/demystifysciPARADIGM DRIFThttps://demystifysci.com/paradigm-drift-showOUR HOMEBREWED MUSIC Check out our band's new album:https://secretaryofnature.bandcamp.com/album/everything-is-so-good-hereVinyl pre-orders available now: https://buy.stripe.com/14A5kC3Od5d21Ms7zPdEs09Follow Helenê & IONS at https://noetic.org00:00 Go! Intro to Psi Phenomena 00:05:00 Media Influence on Psi Research 00:06:12 Dr. Wahbeh's Journey into Psi Research 00:19:00 Historical Context of Channeling Practices 00:24:54 Medicalization and Altered States 00:26:04 Spirit Influence on Mental Health 00:29:27 Historical Context of Spiritualism 00:32:56 Power and Intermediaries in Religion 00:35:12 Personal Experiences with Spirituality 00:39:50 The Nature of Prophecy and Free Will 00:42:00 Interpretation and Influence of Messages 00:47:30 Interconnectedness and Source of Information 00:49:33 Physics vs. Spiritual Experience 00:50:14 Importance of Rigorous Evidence in Telepathy Studies 00:53:37 Controlled Studies vs. Anecdotal Evidence 00:56:43 Challenges of Proving Paranormal Phenomena 00:59:38 Scientific Validity of Psychic Abilities 01:05:04 Emotional Context in Psychic Experiences 01:11:10 Practical Applications and Future of Psychic Research 01:13:21 Exploring Mechanisms of Telepathy 01:21:04 Instrumentalization of Mental Phenomena 01:32:04 Psychokinesis and Random Number Generators 01:36:52 Non-Physical Mechanisms of Interaction 01:37:40 Exploring Physical vs. Non-Physical Mechanisms 01:42:00 Philosophical Debate on Mechanism and Consciousness 01:49:30 Future of Mechanistic Understanding 01:58:30 Imagining Intentionality in Interconnected Fields 02:01:56 Exploring Consciousness Models 02:05:50 Interconnectedness and Humility in Understanding 02:09:43 Transcendent Experiences and Science 02:13:21 Physics and Mysticism: Distinct Yet Connected 02:22:00 Music, Emotion, and Scientific Inquiry 02:25:11 Exploring Diverse Worldviews 02:27:08 Speculating on Telepathy's Impact 02:31:43 Navigating Uncertainty and Truth 02:34:03 Embracing Collaboration for Future Insights#Consciousness, #Telepathy, #TheoreticalPhysics, #QuantumBiology, #neuroscience , #psi , #mindsciences , #NoeticSciences, #consciousness , #brainpower , #psychicenergy, #bigquestions #philosophypodcast , #sciencepodcast, #longformpodcast ABOUS US: Anastasia completed her PhD studying bioelectricity at Columbia University. When not talking to brilliant people or making movies, she spends her time painting, reading, and guiding backcountry excursions. Shilo also did his PhD at Columbia studying the elastic properties of molecular water. When he's not in the film studio, he's exploring sound in music. They are both freelance professors at various universities.

Vilazodone (brand name Viibryd) is an antidepressant with a unique pharmacologic profile compared to most other agents in the SSRI class. While not a first-line choice for every patient, understanding its mechanism, adverse effects, and interaction profile is essential for optimizing therapy and preventing downstream prescribing problems. Mechanism of ActionVilazodone is classified as a selective serotonin reuptake inhibitor (SSRI) and a partial agonist at the 5-HT1A receptor. The SSRI activity increases synaptic serotonin by blocking the serotonin transporter, while partial agonism at 5-HT1A receptors may contribute to antidepressant effects and potentially reduce certain SSRI-associated adverse effects (though clinical evidence for this benefit is mixed). Adverse Effects GI effects – diarrhea, nausea, and vomiting are frequent early in therapy. Taking the medication with food can help minimize these. Insomnia – often dose-related; morning dosing may help. Sexual dysfunction – may be slightly lower than with some SSRIs but still present. Serotonin syndrome – rare but serious, particularly if combined with other serotonergic drugs. Discontinuation syndrome – abrupt cessation can lead to dizziness, irritability, and flu-like symptoms. Drug InteractionsVilazodone is primarily metabolized by CYP3A4. This means: CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin, ritonavir) can increase vilazodone concentrations, potentially worsening side effects—dose reductions may be required. CYP3A4 inducers (e.g., carbamazepine, rifampin, St. John's Wort) can lower drug levels, reducing effectiveness. Other serotonergic agents (e.g., triptans, SNRIs, MAOIs, tramadol, linezolid) increase the risk of serotonin syndrome. Antiplatelets and anticoagulants – SSRIs can impair platelet aggregation, increasing bleeding risk when combined with aspirin, NSAIDs, or warfarin. Prescribing Cascade ExamplesVilazodone's adverse effects can easily lead to unnecessary prescriptions if side effects aren't recognized: GI upset → Acid suppression therapy – Diarrhea or nausea prompts the addition of proton pump inhibitors or antiemetics, instead of adjusting vilazodone dose or timing. Insomnia → Hypnotic initiation – Trouble sleeping results in adding zolpidem or trazodone, without reassessing morning dosing or vilazodone's role. Sexual dysfunction → PDE5 inhibitor prescription – Erectile dysfunction leads to sildenafil use, when the root cause is vilazodone's serotonergic activity. Vilazodone's combination of SSRI and 5-HT1A partial agonist activity makes it somewhat distinct, but its side effect profile and interactions require the same careful monitoring as other antidepressants. Healthcare professionals can play a key role in catching early signs of adverse effects, preventing prescribing cascades, and ensuring drug–drug interactions are managed appropriately.

Hey now, Cabalists! The gang is back and fired up for another episode of The Cabal! Tony's dealing with his dog's unfortunate bout of diarrhea, Chris went out to see Weird Al, and the crew hit the table with a pile of great new games including Above and Below Haunted, Ark Nova: Marine Worlds, El Burro, Heat Pedal to the Metal, Moon Colony Bloodbath, and feature Shackleton Base by Fabio Lopiano and Nestore Mangone, published by Sorry We Are French. After Tony T delivers his always-popular News segment, the gang dives into a discussion on the vital connection between theme and mechanisms in board games. Above and Below Haunted: 00:09:41, Ark Nova: Marine Worlds: 00:18:15, El Burro: 00:27:16, Heat: 00:37:35, Moon Colony Bloodbath: 00:46:319, Shackleton Base: 01:04:09, News with Tony T: 01:38:04, Theme and Mechanism Alignment: 02:31:41. Check out our sponsors Restoration Games at https://restorationgames.com/. Game Toppers at https://www.gametoppersllc.com/. And Game Night Picks at http://gamenightpicks.com/cabal.

Solifenacin is a bladder antimuscarinic medication most commonly used for overactive bladder (OAB) with symptoms of urinary frequency, urgency, and urge incontinence. Like other agents in its class, understanding the pharmacology can help anticipate potential side effects, drug interactions, and downstream prescribing problems. Mechanism of Action Solifenacin selectively blocks muscarinic M3 receptors in the bladder detrusor muscle. Inhibiting these receptors reduces involuntary bladder contractions, increases bladder capacity, and delays the urge to void. While M3 selectivity may theoretically reduce side effects compared to nonselective antimuscarinics, in clinical practice, many anticholinergic effects still occur. Adverse Effects Because muscarinic receptors are present throughout the body, solifenacin can lead to a range of anticholinergic adverse effects: Dry mouth – among the most common, can be significant enough to cause dental issues with long-term use. Constipation – especially problematic in older adults; severe cases may require hospitalization. Blurred vision – due to impaired accommodation. Cognitive impairment – increased risk in older adults, particularly with cumulative anticholinergic burden. Urinary retention – paradoxical worsening in patients with bladder outlet obstruction. Drug Interactions CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin, ritonavir) can increase solifenacin plasma concentrations, raising the risk of side effects. Other anticholinergics (e.g., diphenhydramine, tricyclic antidepressants, other bladder antimuscarinics) can result in additive toxicity and higher anticholinergic burden. QT-prolonging drugs (e.g., amiodarone, certain fluoroquinolones) may have additive cardiac risk since solifenacin has been associated with QT prolongation in rare cases. Prescribing Cascade Examples Constipation → Laxative initiation – A patient starts solifenacin for OAB and develops severe constipation, leading to chronic use of stimulant laxatives like senna or bisacodyl. Dry mouth → Mouth rinse prescription – Dry mouth is treated with saliva substitutes or prescription rinses, instead of reassessing the anticholinergic therapy. Cognitive decline → Donepezil initiation – In older adults, cognitive impairment may be mistaken for dementia progression, leading to cholinesterase inhibitor prescribing—directly counteracting the anticholinergic effects of solifenacin. Solifenacin can be an effective treatment for OAB, but the risk of adverse effects and prescribing cascades—especially in older adults—cannot be ignored. Healthcare professionals should regularly review the indication, monitor for anticholinergic burden, and look for opportunities to deprescribe when appropriate.

We Got This With Mark and Hal determines the best door opening mechanism of all time. This decision is legally binding.

Melissa and Jam explore the science behind why sweat is salty. They discuss personal experiences with sweating, the types of sweat glands, and the chemical processes involved in sweat production. The episode explains how osmosis, ion channels, and salt concentrations contribute to the movement of sweat through sweat glands to the skin's surface. They also touch on evolutionary aspects and the role of sweat in cooling the body. For anyone curious about the chemistry of everyday life, this episode offers an accessible and intriguing explanation. 00:00 Introduction: Why is Sweat Salty? 00:27 Personal Experiences with Sweat 01:32 The Science Behind Sweat 02:00 Meet the Hosts 02:20 Types of Sweat Glands 04:30 How Sweat Reaches the Skin 07:31 The Role of Salt in Sweat 14:20 Health Indicators in Sweat 17:01 Understanding Osmosis and Interstitial Fluid 17:39 Evolutionary Perspective on Sweating 20:01 Mechanism of Sweat Glands 22:41 Sweat Composition and Function 27:39 Personal Sweating Experiences 33:47 Supporting the Show and Community ★ Support this podcast on Patreon ★ ★ Buy Podcast Merch and Apparel ★ Check out our website at chemforyourlife.com Watch our episodes on YouTube Find us on Instagram, Twitter, and Facebook @ChemForYourLife References from this episode: https://pmc.ncbi.nlm.nih.gov/articles/PMC6773238/ https://pubs.rsc.org/en/content/articlehtml/2024/lc/d3lc00874f#cit23 https://pubs.acs.org/doi/full/10.1021/acsnano.4c10344 Thanks to our monthly supporters Vince W Julie S. Heather R Autoclave Chelsea M Dorien VD Scott B Jessie R Ciara L J0HNTR0Y Jeannette N Cullyn R Erica B Elizabeth P Sarah M Rachel R Letila Katrina B Suzanne P Venus R Lyn S Jacob T Brian K Emerson W Kristina G Timothy P Steven B Chris and Claire S Chelsea B Avishai B Hunter R ★ Support this podcast on Patreon ★ ★ Buy Podcast Merch and Apparel ★ Check out our website at chemforyourlife.com Watch our episodes on YouTube Find us on Instagram, Twitter, and Facebook @ChemForYourLife

It's no secret that humans are conditioned to look for the negative.    The constant battle against negativity rages every single day.    Print.    TV.    Social media.    We can't get through our days without some negative news trying to penetrate our mentality.    What happens when we're faced with negativity is our brains are positioned to fight or flight.    But, what if there was a way to break out of this.    There is a way, and it takes focus, consistency, and practice.    And it's possible to do it easily.    The first thing you have to do is correct the trigger when you want to dive into the same stream of negativity the world brings you.    If someone wants to argue, find a way to diffuse it, no matter who is right or wrong.    When someone comes in and throws things into chaos, don't accept it as a problem you need to solve.    In moments of great stress,  and negativity, motivate yourself with love, gratitude, and abundance.    When you rewire your mind against its nature, you can operate from a place of love.    It's going to take some work, but when you do, watch the world you create change right in front of your face.    Most of the things we worry about never come to fruition.    Follow the path of inpenetrable positivity and let life flow.    About the ReWire Podcast   The ReWire Podcast with Ryan Stewman – Dive into powerful insights as Ryan Stewman, the HardCore Closer, breaks down mental barriers and shares actionable steps to rewire your thoughts. Each episode is a fast-paced journey designed to reshape your mindset, align your actions, and guide you toward becoming the best version of yourself. Join in for a daily dose of real talk that empowers you to embrace change and unlock your full potential.    Learn how you can become a member of a powerful community consistently rewiring itself for success at https://www.jointheapex.com/   Rise Above

Recorded with a live audience in Cambridge, this captivating conversation delves deep into the life and career of a cultural force of the last half-century. Known of course for his iconic role as Baldrick in Blackadder, Sir Tony's sharp intelligence and dry humour have had a formative influence on generations.  In this candid discussion, he opens up about the unexpected turns and profound challenges that have shaped his extraordinary journey as an actor, presenter, documentary maker and writer. You'll hear his deeply personal reflections on fatherhood, insights into the creative process behind his recently announced novel, and the powerful lessons learned from a lifetime of experiences, both public and private.  Prepare for an engaging, wise, and moving conversation that explores the transformative power of vulnerability and the importance of finding meaningful connection. This is a unique opportunity to hear a national treasure like never before. ✨ IN THIS EPISODE: 00:00 Intro 00:45 Tony Robinson's Early Life and Career 03:13 Fatherhood and Family 04:55 Writing and Publishing a Novel 10:50 The Impact of Blackadder 13:16 Challenges and Conflicts in Blackadder 16:33 Height and Personal Insecurities 20:42 Childhood and Adolescence Struggles 22:41 Growing Up in the Shadow of WWII 24:49 The Ups and Downs of Gambling 27:28 Early Career and Poker Lessons 29:29 Child Actor Earnings and Capitalism 34:23 Dealing with Alzheimer's in the Family 37:03 Reflecting on Personal Failures 44:56 Finding Meaningful Relationships

Fat Loss & Metabolism with Dr. Ben Bikman Challenging the dogma surrounding heart disease. (1:32) Is there a connection between dementia and heart disease? (12:05) Strength training and Alzheimer's. (17:49) Learning something new helps put off dementia. (22:45) The connection between insulin resistance and your body's inability to fight off infection. (25:17) We put TOO much attention on total cholesterol. (27:55) Fat cells dynamics explained. (30:13) Why your metabolism is EXTREMELY complex. (44:14) Mitochondrial uncoupling. (48:51) Ketones and athletic performance. (55:39) The problem with DNP. (58:11) Why he is a HUGE advocate of creatine. (1:01:03) The brain loves ketones. (1:04:33) Keep your running shoes in the closet, GO STRENGTH TRAIN! (1:05:32) The metabolic origins of chronic disease. (1:08:10) How GLP-1s are being overused and the proper way to use them. (1:14:48) The resurgence of religion. (1:37:57) As a scientist, did he ever doubt his faith? (1:41:28) The most profound moment of his life. (1:45:51) Related Links/Products Mentioned Why We Get Sick: The Hidden Epidemic at the Root of Most Chronic Disease - and How to Fight It – Book by Dr. Benjamin Bikman How Not to Get Sick: A Cookbook and Guide to Prevent and Reverse Insulin Resistance, Lose Weight, and Fight Chronic Disease – Book by Dr. Benjamin Bikman Unlock sharper focus and support long-term brain health with Ketone-IQ—clean brain fuel for deep work, mental clarity, and sustained energy with no crash. Get 30% off your subscription, plus a free gift with your second shipment at https://ketone.com/MINDPUMP June Special: Shredded Summer Bundle or Bikini Bundle 50% off! ** Code JUNE50 at checkout ** Most heart attack patients' cholesterol levels did not indicate cardiac risk Study: Doubling Saturated Fat in the Diet Does Not Increase Saturated Fat in Blood Insulin signal transduction pathway Mind Pump #1922: Fatphobia & Other Lies That Are Keeping You Fat, Unhealthy & Sick Diabulimia: Why This Eating Disorder Is So Dangerous for People with Diabetes Harris-Benedict equation - Wikipedia Mitochondrial Uncoupling: A Key Controller of Biological Processes in Physiology and Diseases DNP (Dinitrophenol): Overview, Mechanism, and Risks Mind Pump #2497: The Amazing & Weird Side Effects of Creatine Muscle strength and fitness linked to reduction in cancer deaths Fighting Cancer By Putting Tumor Cells On A Diet - NPR Healthy Weight Loss Maintenance with Exercise, Liraglutide, or Both Combined Attenuated GLP-1 secretion in obesity: cause or consequence? Mind Pump #2597: Before You Take Ozempic, Wegovy, or Mounjaro Listen to This! Liraglutide modulates lipid metabolism via ZBTB20-LPL pathway Mind Pump #872: Dr. Warren Farrell- The Boy Crisis Mind Pump Podcast – YouTube Mind Pump Free Resources Featured Guest/People Mentioned Benjamin Bikman (@benbikmanphd) Instagram Website Zach Bitter (@zachbitter) Instagram  Thomas N. Seyfried (@thomasseyfriedbc) Instagram Warren Farrell, PhD (@drwarrenfarrell) X/Twitter