Podcasts about Mechanism

Getting lots of feedback but making zero moves? That's what happens when your breakthrough session becomes an advice room. It can feel productive in the moment, but you leave with more opinions than decisions — and the same problem shows up again next week. This episode breaks down what real breakthrough sessions do differently and the nine mechanisms that lead to action.Topics discussed:Why breakthrough sessions often fail (01:16)Mechanism #1: name the real decision (02:39)Mechanism #2: separate facts from assumptions (03:11)Mechanism #3: find the hidden trade-offs (03:43)Mechanism #4: simplify the problem (04:17)Mechanism #5: advice comes after clarity (05:56)Mechanism #6: no competing for airtime (06:23)Mechanism #7: use healthy disagreement (06:45)Mechanism #8: ownership stays with the leader (07:11)Mechanism #9: proof comes after the session (07:30)Tired of feeling stuck? Download our FREE Limitless Growth eBook for strategies for continuous improvement, time management, and leadership skills that make an impact: https://meplusultra.com/growth/Download our FREE Client Centric Leader eBook for a deeper playbook on building loyalty no competitor can steal: https://meplusultra.com/ebooks/Apply for the Me Plus Ultra Mastermind to connect with elite entrepreneurs who solve real problems together: https://MePlusUltra.comSubscribe so you don't miss any episodes:Apple Podcasts: https://apple.co/3SN2fHnSpotify: https://open.spotify.com/show/74bfJL9J2fjevQEvi17ekUYouTube: https://www.youtube.com/@MePlusUltraNetwork/Connect with Me Plus Ultra:https://www.instagram.com/me_plus_ultra/https://www.facebook.com/MePlusUltra/https://www.facebook.com/groups/1011061052968028/https://x.com/Me_Plus_Ultra/Connect with Scott Joseph:https://www.linkedin.com/in/ScottJosephhttps://www.instagram.com/scotttjoseph/https://www.facebook.com/ScottTJoseph/https://x.com/ScottTJoseph1This episode was produced by Podcast Boutique https://www.podcastboutique.com

Pimavanserin is an atypical antipsychotic approved for the treatment of hallucinations and delusions associated with Parkinson’s disease psychosis. Unlike traditional antipsychotics, it does not block dopamine receptors, making it a unique option for patients with Parkinson’s disease who are highly sensitive to dopamine antagonism. Mechanism of Action Pimavanserin works primarily as a selective serotonin 5-HT2A inverse agonist and antagonist, with minor activity at 5-HT2C receptors. This dopamine-sparing effect is the key reason it does not worsen motor symptoms in Parkinson’s disease. Adverse Effects The most commonly reported side effects include peripheral edema, nausea, confusion, and hallucinations. QT interval prolongation is a clinically important concern, especially in patients with existing cardiac risk factors. Somnolence may occur but is generally less prominent compared with dopamine-blocking antipsychotics. Warnings and Precautions Pimavanserin carries a boxed warning for increased mortality in elderly patients with dementia-related psychosis, consistent with other antipsychotics. It should not be used in patients with known QT prolongation, a history of ventricular arrhythmias, or in combination with other QT-prolonging agents when possible. Drug Interactions Strong CYP3A4 inhibitors, such as ketoconazole or clarithromycin, can significantly increase pimavanserin concentrations and require dose reduction. Strong CYP3A4 inducers, such as rifampin or carbamazepine, may reduce efficacy and should generally be avoided. Additive QT prolongation may occur when combined with other QT-prolonging medications, including certain antiarrhythmics, fluoroquinolones, and macrolide antibiotics. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources! NAPLEX Study Materials BCPS Study Materials BCACP Study Materials BCGP Study Materials BCMTMS Study Materials Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101

Certified coach and professor Kathleen Muldoon and co-founder of Ryan House and Children's Respite Homes of America Jonathan Cottor discuss the article "The need for pediatric respite care." Kathleen shares the personal story of raising her son Gideon who lives with over 42 medical diagnoses and explain why the family had to move across the country to find safety. They highlight the critical difference between taking a break and surviving the relentless cycle of 24/7 medical vigilance required for medically complex children. The conversation advocates for the expansion of pediatric respite homes in the U.S. while urging clinicians to recognize that caregiver well-being is inseparable from patient health. We must acknowledge that keeping a family together often depends on the support they receive outside the hospital walls. Partner with me on the KevinMD platform. With over three million monthly readers and half a million social media followers, I give you direct access to the doctors and patients who matter most. Whether you need a sponsored article, email campaign, video interview, or a spot right here on the podcast, I offer the trusted space your brand deserves to be heard. Let's work together to tell your story. PARTNER WITH KEVINMD → https://kevinmd.com/influencer SUBSCRIBE TO THE PODCAST → https://www.kevinmd.com/podcast RECOMMENDED BY KEVINMD → https://www.kevinmd.com/recommended

EU STRUGGLES WITH RUSSIAN ASSETS AND AID Colleague Judy Dempsey. Judy Dempsey discusses the EU's difficulty in utilizing frozen Russian assets and the "defeat" for Chancellor Merz regarding the funding mechanism for Ukraine. NUMBER 1 1890 SAXONY

What if thousands of steps of gentle walking aren't giving you the brain protection you think they are? In this solo episode, I break down one of the most important exercise studies published in Nature Communications and what it means for your brain, longevity, and Alzheimer's risk. Tracking over 73,000 people for eight years using wearables, the findings are shocking: one minute of vigorous exercise is worth up to 10 minutes of moderate activity — not the outdated 2-to-1 rule. For diabetes prevention, it's nearly 10-to-1. For cardiovascular mortality, it's 8-to-1. And here's what no one is saying: every outcome measured — heart disease, diabetes, metabolic dysfunction — is an independent risk factor for Alzheimer's and dementia. I explain why vigorous exercise is so powerful for your brain: shear stress that strengthens blood vessels, lactate that triggers BDNF, muscle fiber recruitment that protects against falls and cognitive decline, and glucose regulation that defends against insulin resistance — a driver of neurodegeneration. Think vigorous exercise is out of reach? Good news: the study defines it as brisk stairs, carrying groceries, or playing actively with your kids. No gym required — just effort. Just 3–4 minutes of vigorous bursts per day can reduce all-cause mortality by 40% and cardiovascular events by nearly 50%. For women over 40, this is critical. Two-thirds of Alzheimer's cases are women, and perimenopause is a vulnerability window for the brain. Vigorous exercise can partially compensate for declining estrogen by improving glucose regulation, reducing inflammation, and protecting the brain in ways gentle movement cannot. *** Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/brain-code-yt Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Rho NutritionYou can get 20% off with the code NEURO at https://rhonutrition.com Function HealthVisit https://functionhealth.com/louisa or use gift code NEURO100 at sign-up to own your health. AquaTruGo to https://AquaTru.com now for 20% off using promo code NEURO. TimelineHead to https://www.timeline.com/neuro to get 20% off. Cure HydrationGet 20% off your first order at https://curehydration.com/neuro with code NEURO. *** I'm Louisa Nicola — clinical neurophysiologist — Alzheimer's prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer's risk — and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Topics discussed:00:00:00 Introduction: The Exercise Intensity Revolution 00:01:02 The Study That Changes Everything 00:04:50 The Flawed Foundation: Why Guidelines Were Wrong 00:06:50 The Real Numbers: 4 to 10 Times More Powerful 00:08:53 The Brain Connection No One Is Talking About 00:15:32 Mechanism 1: Shear Stress and Cerebral Blood Flow 00:17:38 Mechanism 2: Lactate and BDNF Production 00:19:25 Mechanism 3: Type 2 Muscle Fibers and Myokines 00:24:30 Mechanism 4: Glucose Regulation and Mitochondrial Health 00:28:18 VILPA: The 3-Minute Daily Game Changer 00:32:16 Women and Menopause: The Critical Window 00:35:19 Practical Protocols: What to Do Starting Today Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of IDEA Collider, hosts Mike and Rick revisit a pivotal project from over a decade ago, the Reblozyl project, undertaken in collaboration with Acceleron and Celgene. Rick, the head of Growth and Innovation at IDEA, reminisces about the early days leading to the successful positioning and market shaping of luspatercept across different hematological indications. The episode features insightful contributions from Robin, Jane, and Tracy, key players from Acceleron and Celgene, who share their experiences and the collaborative efforts that enabled them to redefine the market. The discussion covers the strategic approach to overcoming competitive benchmarking, the importance of a unified messaging strategy, and the critical role of internal and external collaboration. They also reflect on the impact of their efforts on the lives of many patients and offer advice for future teams working on complex drug development projects. The episode concludes with a recognition of the rare and valuable collaborative human elements that drove the success of the Reblozyl project.Episode Timestamps;00:00 Introduction and Welcome00:27 Rick's Background and Project Overview02:31 Client Team Introductions05:32 Collaboration and Challenges13:29 Defining the Mechanism and Market Positioning23:52 Communication and Alignment27:48 Navigating Internal and External Communication33:15 Launch, Reflections, and Lessons Learned41:14 Final Thoughts and Acknowledgements Keep up with the guests;Robyn Blackburn  - Director Global Commercial Strategy CAR-T at Kite Pharmahttps://www.linkedin.com/in/robyn-blackburn-805b8b13/Jayne Butler - Director of Strategic Initiatives at Fingerpaint Brandinghttps://www.linkedin.com/in/jaynebutler/Tracey Sacco - Former SVP Global Strategic Marketing at Acceleronhttps://www.linkedin.com/in/tracey-sacco-53 2a034/Rick Ritacco - Head of Growth and Innovationhttps://www.linkedin.com/in/rritacco/ Follow Mike Rea On;Website: https://ideacollider.simplecast.com/X: https://x.com/ideapharmaLinkedIn: https://www.linkedin.com/in/bigidea/ Listen to more fantastic podcast episodes: https://ideacollider.simplecast.com/

Luke & Phil George-Hypnotic Mechanism by Beenoise Rec

Breuer, J. & Freud, S. (1893) On the Psychical Mechanism of Hysterical Phenomena: Preliminary Communication from Studies on Hysteria. I do not own the rights to this article. This is from the Standard Edition of the Complete Psychological Works of Sigmund Freud. This podcast is for educational purposes only.

Recent FDA actions are reshaping key aspects of drug and biologic development, including the Commissioner's National Priority Voucher program, the "plausible mechanism" pathway for personalized therapies, and new draft guidance aimed at streamlining biosimilars and interchangeables. Join Washington, D.C. partner Nathan Beaton and counsel Monica Groat and Chad Jennings as they discuss how these moves differ from traditional policy-making, as well as the practical implications for pricing, manufacturing, M&A, and litigation risk in the healthcare and life sciences industry.   This podcast is provided as a service of Latham & Watkins LLP. Listening to this podcast does not create an attorney client relationship between you and Latham & Watkins LLP, and you should not send confidential information to Latham & Watkins LLP. While we make every effort to assure that the content of this podcast is accurate, comprehensive, and current, we do not warrant or guarantee any of those things and you may not rely on this podcast as a substitute for legal research and/or consulting a qualified attorney. Listening to this podcast is not a substitute for engaging a lawyer to advise on your individual needs. Should you require legal advice on the issues covered in this podcast, please consult a qualified attorney. Under New York's Code of Professional Responsibility, portions of this communication contain attorney advertising. Prior results do not guarantee a similar outcome. Results depend upon a variety of factors unique to each representation. Please direct all inquiries regarding the conduct of Latham and Watkins attorneys under New York's Disciplinary Rules to Latham & Watkins LLP, 1271 Avenue of the Americas, New York, NY 10020, Phone: 1.212.906.1200

Two questions I get a lot from people who are new to Biohacking and cognitive enhancers are...❓ Which Smart Drugs actually work and have science behind them?❔ Which Nootropic should I get started with?⚡ My answer to both questions is the same: PiracetamIt has a significant body of scientific evidence behind it; over 750 human studies and academic papers have been published about Piracetam on PubMed, with over ten meta-analysis papers in just the past decade.9:51 Scientific Research11:52 Memory Enhancement17:50 Mitochondrial Nootropic19:47 Stroke Recovery20:12 Cognitive Enhancer20:50 Verbal Fluency22:45 Cognitive Decline24:26 Vs Alzheimer's24:53 Mechanism of Action26:42 History27:13 Vs Depression29:50 Sources35:43 Piracetam Non-Responders?37:10 Tolerance37:28 Post-Piracetam Intelligence Deficit43:09 Addiction or Dependence?43:50 Experiential46:47 Featured in Fiction47:21 Dosage & Cofactors49:22 Side Effects & Risks56:23 ConclusionRead Meta-Analysis

Two questions I get a lot from people who are new to Biohacking and cognitive enhancers are...❓ Which Smart Drugs actually work and have science behind them?❔ Which Nootropic should I get started with?⚡ My answer to both questions is the same: PiracetamIt has a significant body of scientific evidence behind it; over 750 human studies and academic papers have been published about Piracetam on PubMed, with over ten meta-analysis papers in just the past decade.9:51 Scientific Research11:52 Memory Enhancement17:50 Mitochondrial Nootropic19:47 Stroke Recovery20:12 Cognitive Enhancer20:50 Verbal Fluency22:45 Cognitive Decline24:26 Vs Alzheimer's24:53 Mechanism of Action26:42 History27:13 Vs Depression29:50 Sources35:43 Piracetam Non-Responders?37:10 Tolerance37:28 Post-Piracetam Intelligence Deficit43:09 Addiction or Dependence?43:50 Experiential46:47 Featured in Fiction47:21 Dosage & Cofactors49:22 Side Effects & Risks56:23 ConclusionRead Meta-Analysis

Today, we're diving into a subtle yet destructive behavioral pattern: blame-flipping. You know the feeling – every issue somehow becomes your fault, even when it's clearly caused by someone else's actions. It's a defense mechanism, or often, a manipulative tactic where an individual simply refuses to take responsibility for their own mistakes or problems.Become a supporter of this podcast: https://www.spreaker.com/podcast/lets-talk-sex--5052038/support.

https://www.otplinks.com 0:00 Welcome & today's focus: Retatrutide and “chasing the biggest number” 1:11 On The Pen intro, live schedule (Mon/Wed/Fri) & housekeeping 2:10 How Dave first heard about retatrutide (work trip, early phase 1 data) 3:35 Flashback clip: early excitement about retatrutide phase 3 trials 4:40 Why this new retatrutide data feels different for obesity medicine 5:32 TRIUMPH-4 trial overview: obesity + knee osteoarthritis population 7:00 Headline results: 28.7% average weight loss, surgery-level efficacy 8:47 Breaking down weight loss by dose (9 mg vs 12 mg; 25–35% loss rates) 11:05 What “efficacy estimate” really means (race-track analogy) 13:28 Real-world view: treatment-regimen estimate (20–23.7%) vs trial ideal 15:40 Mechanism refresher: GIP, GLP-1, glucagon and why RETA differs from TIRZ 18:05 Side effects, dysesthesia/allodynia & who stopped treatment (BMI differences) 21:02 Why the lower doses matter & who actually needs 30% weight loss 24:15 From “just make the scale go down” to quality of weight loss & body composition 28:05 Future focus: health, longevity, and peptides beyond hitting goal weight 30:40 Viewer Q&A: combining RETA + TIRZ, amylin (eloralintide) combos & “talk to your doctor” 34:38 How retatrutide changes the next decade of obesity treatment conversations 37:22 News update: high-dose Wegovy 7.2 mg approval in the EU & US outlook 40:55 Orforglipron oral GLP-1: liver-signal concerns & fast-track FDA review 45:20 Why small-molecule oral GLP-1s aren't the same as injectable peptides 48:40 New topic: Indiana “Safe Drug Act of 2025” and why Dave is concerned 51:02 Production caps, “essentially a copy” language & shifting power from prescribers to FDA 54:28 How the bill undermines personalization while ignoring real safety tools 57:05 Safety theater vs real safeguards: API sourcing, sterility & adverse-event reporting 59:45 Who actually gets hit: compliant 503A/503B compounders vs existing bad actors 1:02:05 Call to action: petition at otplinks.com & why patient voices matter 1:05:10 Change.org impact, media attention & centering the patient perspective 1:07:30 Final Q&A, subscribe, obesity.news email list & closing thanks Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

PREVIEW — Chris Riegel — "The Great Heist": China's Intellectual Property Theft Strategy. Riegel argues that Chinahas systematically employed intellectual property theft as a strategic mechanism to advance from technological desperation toward status as a near-peer American rival, systematically acquiring technologies while circumventing legitimate licensing and development pathways. Riegel documents that American corporations frequently ignored or tolerated Chinese IP theft in exchange for access to the lucrative Chinese domestic market, including the Cisco-Huaweicase illustrating corporate preference for market access over intellectual property protection. Riegel acknowledges that China now conducts original research and technological innovation, yet systematically rejects international intellectual property law regimes and refuses to recognize or enforce IP rights, maintaining institutional resistance to the legal frameworks protecting legitimate innovation and development within Western economies. 1922

Economist Paul Milgrom is celebrated for his Nobel Prize-winning work on auction theory and design. But he has published a wide range of other innovative, influential research throughout his career – including a book and articles emerging from his 1991-92 CASBS fellowship. Gani Aldashev (CASBS fellow, 2024-25) engages Milgrom on highlights of this often-collaborative or cross-disciplinary work on organizational behavior, the institutional roots of trust and cooperation, social choice for environmental policy, and more.PAUL MILGROM: Stanford faculty page | Personal website | Nobel Prize page | Nobel bio | Wikipedia page| CASBS page |Gani Aldashev: Georgetown faculty page | CASBS page | Google Scholar page |PAUL MILGROM WORKS REFERENCED IN THIS EPISODE:Economics, Organization, and Management (Prentice Hall, 1992), coauthored with John Roberts (CASBS fellow, 1991-92)"Multitask Principal-Agent Analyses: Incentive Contracts, Asset Ownership, and Job Design," The Journal of Law, Economics, and Organization (1991), coauthored with Bengt Holmstrom"Complementarities and Fit Strategy, Structure, and Organizational Change in Manufacturing," Journal of Accounting and Economics (1995), coauthored with John Roberts"Complementarities, Momentum, and the Evolution of Modern Manufacturing," The American Economic Review (1991), coauthored with Yingyi Qian, John Roberts"Complementarities and Systems: Understanding Japanese Economic Organization," Estudios Economicos (1994), coauthored with John Roberts"The Role of Institutions in the Revival of Trade: The Law Merchant, Private Judges, and the Champagne Fairs," Economics & Politics (1990), coauthored with Douglass North (CASBS fellow, 1987-88) and Barry Weingast (CASBS fellow, 1993-94)Learn about the Champagne Fairs on Wikipedia"Coordination, Commitment and Enforcement: The Case of the Merchant Guild," Journal of Political Economy (1994), coauthored with Avner Greif (CASBS fellow, 1993-94), Barry Weingast"Is Sympathy an Economic Value? Philosophy, Economics, and the Contingent Valuation Method," in Contingent Valuation: A Critical Assessment, J.A. Hausman, ed. (Elsevier, 1993)"Kenneth Arrow's Last Theorem," Journal of Mechanism and Institution Design (2024)Other works referenced in this episode:Oliver Williamson, The Economic Institutions of Capitalism: Firms, Markets, Relational Contracting (Mcmillan, 1985). Much of this book was written at CASBS during Williamson's 1977-78 CASBS fellowship.Works emerging from Milgrom's CASBS fellowshipsMilgrom's collaborations with, intellectual interactions with, or responses to other Nobel Prize winners in this episode:Oliver Williamson (CASBS fellow 1977-78, Nobel Prize 2009)Bengt Holmstrom (Nobel Prize 2016)Robert Wilson (CASBS fellow 1977-78, Nobel Prize 2020)Ronald Coase (CASBS fellow 1958-59, Nobel Prize 1991)Douglass North (CASBS fellow 1987-88, Nobel Prize 1993)Kenneth Arrow (CASBS fellow 1956-57, Nobel Prize 1972) Center for Advanced Study in the Behavioral Sciences (CASBS) at Stanford UniversityExplore CASBS: website|Bluesky|X|YouTube|LinkedIn|podcast|latest newsletter|signup|outreach​Human CenteredProducer: Mike Gaetani | Audio engineer & co-producer: Joe Monzel |

Livestream with Yuri Rashkin----------SILICON CURTAIN FILM FUNDRAISERA project to make a documentary film in Ukraine, to raise awareness of Ukraine's struggle and in supporting a team running aid convoys to Ukraine's front-line towns.https://buymeacoffee.com/siliconcurtain/extras----------https://car4ukraine.com/campaigns/autumn-harvest-silicon-curtainDonate and Receive - Collectable PatchAUTUMN HARVEST TRUCKS 2025. Part of our 2025 patch collection. Everyone who contributes €100 (~$115) or more will be able to receive it.For our Autumn patch, we present the Galician Lion. The rampant lion represents power and intelligence. It has represented Western Ukrainian people since the 1100s. The Ruthenian lion, also known as the Ukrainian lion or Galician lion, was featured on the historic coat of arms of: The Kingdom of Galicia-Volhynia (Ruthenia)1199-1349, The battle flag of the Lviv land in the Battle of Tannenberg, 1410 The Ruthenian Voivodeship (Administration) 1434-1772 and The Western Ukrainian People's Republic 1918-1919. The Ukrainian national liberation movement, 1948----------SILICON CURTAIN LIVE EVENTS - FUNDRAISER CAMPAIGN Events in 2025 - Advocacy for a Ukrainian victory with Silicon Curtainhttps://buymeacoffee.com/siliconcurtain/extrasOur events of the first half of the year in Lviv, Kyiv and Odesa were a huge success. Now we need to maintain this momentum, and change the tide towards a Ukrainian victory. The Silicon Curtain Roadshow is an ambitious campaign to run a minimum of 12 events in 2025, and potentially many more. Any support you can provide for the fundraising campaign would be gratefully appreciated. https://buymeacoffee.com/siliconcurtain/extrasWe need to scale up our support for Ukraine, and these events are designed to have a major impact. Your support in making it happen is greatly appreciated. All events will be recorded professionally and published for free on the Silicon Curtain channel. Where possible, we will also live-stream events.https://buymeacoffee.com/siliconcurtain/extras----------SUPPORT THE CHANNEL:https://www.buymeacoffee.com/siliconcurtainhttps://www.patreon.com/siliconcurtain----------TRUSTED CHARITIES ON THE GROUND:Save Ukrainehttps://www.saveukraineua.org/Superhumans - Hospital for war traumashttps://superhumans.com/en/UNBROKEN - Treatment. Prosthesis. Rehabilitation for Ukrainians in Ukrainehttps://unbroken.org.ua/Come Back Alivehttps://savelife.in.ua/en/Chefs For Ukraine - World Central Kitchenhttps://wck.org/relief/activation-chefs-for-ukraineUNITED24 - An initiative of President Zelenskyyhttps://u24.gov.ua/Serhiy Prytula Charity Foundationhttps://prytulafoundation.orgNGO “Herojam Slava”https://heroiamslava.org/kharpp - Reconstruction project supporting communities in Kharkiv and Przemyslhttps://kharpp.com/NOR DOG Animal Rescuehttps://www.nor-dog.org/home/-----------

From an interview discussing the negotiations-mechanism with Israel, conditions for economic recovery, Hezbollah's status today and what hope means in 2025 0:00 Mechanism for negotiations 1:53 Conditions for economic recovery 3:10 Hezbollah today 3:57 Meaning of hope

In this episode, we explore the science and clinical potential of molecular hydrogen — one of the smallest and most fascinating therapeutic molecules in medicine. Once dismissed as biologically inert, hydrogen gas is now recognized for its strong antioxidant, anti-inflammatory, and cell-signaling effects. We'll look at how integrative medicine practitioners are using hydrogen therapy to support mitochondrial health, reduce oxidative stress, and improve recovery across various conditions. Join us as we examine the research, mechanisms, and practical uses of molecular hydrogen in modern clinical care.   Key Takeaways To Tune In For: (01:57) – Greg Mann's Healing Journey (07:04) – The Origin of Hydrogen Research (11:56) – Molecular Hydrogen's Mechanism of Action (15:20) – Hydrogen's Clinical Applications (19:54) – Hydrogen for Strokes and Brain Health (39:15) – Ensuring Hydrogen Purity and Access   Resources talked about in this episode: YouTube

⭐ Guest Bio – Ola Wolny (Self Mastery Quest)Ola Wolny is the creator of Self Mastery Quest, a platform dedicated to decoding the deeper, hidden structure of the reality we inhabit. Her work focuses on how human consciousness interacts with the architecture of this realm, emphasizing that the zodiac is not merely symbolic—but a functional mechanism, a coded matrix system that predetermines energetic pathways, lessons, patterns, and incarnational contracts.Through her YouTube teachings, her private sessions, and her research, Ola guides people through identifying where they are trapped in the zodiac-based programming and how to reclaim autonomy, intuition, and soul sovereignty.Her work merges gnosis, esoteric cosmology, and practical self-mastery.Website: SelfMasteryQuest.comYouTube: https://www.youtube.com/@olawolnyselfmasteryquest

In this episode, Dr. Sharon Niv discusses her work at Joyus, a public benefit company focused on revolutionizing mental health care through personalized at-home microdose ketamine treatments.    Dr. Sharon explains the history of ketamine as a treatment for mental health, its mechanisms of action, and the importance of community support in the healing process.    Nick asks Dr. Sharon questions that address common concerns and stigma surrounding ketamine treatment, emphasizing its low risk and potential benefits.    Their conversation also explores the role of neuroplasticity in mental health recovery and the future of AI in therapy.    Dr. Sharon provides insights into personalized treatment protocols and encourages both patients and therapists to consider the benefits of ketamine therapy.   Key Takeaways:    Dr. Sharon Niv is a cognitive psychologist bridging neuroscience and therapy. Joyus offers personalized at-home microdose ketamine treatments. Ketamine was first synthesized in the 1950s and is used safely in medical settings. The drug has shown promise in treating severe depression and suicidality. Ketamine works primarily on the glutamate system, unlike traditional psychedelics. Lower doses of ketamine can provide therapeutic benefits without destabilizing experiences. Community support is crucial for individuals undergoing ketamine treatment. Neuroplasticity allows the brain to change and adapt, which is enhanced by ketamine. Personalized treatment protocols are essential for effective ketamine therapy. AI has potential in mental health, but should not replace human therapists.   Chapters   00:00 Introduction to Dr. Sharone Niv and Her Work 02:58 The Journey to Psychology and Entrepreneurship 05:47 The History and Safety of Ketamine 08:45 Ketamine as a Treatment for Mental Health 11:36 Understanding Ketamine's Mechanism and Effects 14:44 The Psycholytic State and Its Benefits 17:40 Addressing Stigma and Concerns Around Psychedelics 20:48 The Joyus Approach to Microdosing Ketamine 23:24 Personal Experiences and Emotional Release 26:45 The Importance of Connection and Exploration 27:14 Exploring Psychoactive Substances and Their Impact 28:14 The Tragic Story of Matthew Perry 32:56 Neuroscience and Mental Health: The Role of Neuroplasticity 39:45 Personalized Treatment Protocols for Mental Health 45:22 Community Support in Mental Health Treatment 47:48 The Future of AI in Therapy 53:07 The Dark Side of AI in Mental Health 54:37 Innovative Uses of AI in Therapy 56:09 Training Therapists for New Technologies 59:43 The Journey of Integrating Ketamine Treatment 01:02:09 Encouragement for Patients and Therapists 01:04:22 Understanding the Risks and Benefits of Ketamine 01:09:52 Navigating the Decision to Try Ketamine 01:12:08 Practical Considerations for Microdosing Ketamine Find Dr. Sharon Niv here: Instagram: https://www.instagram.com/joyous.team/  Facebook: https://www.facebook.com/joyous.friends   Website: https://www.joyous.team/  LinkedIn: https://www.linkedin.com/in/sharon-niv/ | https://www.linkedin.com/company/joyousteam/ Find Nick Thompson here: Instagram: https://www.instagram.com/nthompson513/  |  https://www.instagram.com/the_ucan_foundation/  YouTube: https://www.youtube.com/@EyesWideOpenContent   LinkedIn: https://www.linkedin.com/in/nickthompson13/     UCAN Foundation: https://theucanfoundation.org/  Website: https://www.engagewithnick.com/     

2/8. Pigeons: The Great Communicators and Wartime Heroes — Steven Moss — Moss discusses the humble pigeon as a paradoxical feral bird species possessing extraordinary homing capabilities that made it invaluable as a communications mechanism. Although the famous narrative of Nathan Rothschild using pigeons following the Battle of Waterloo is apocryphal, pigeons were genuinely crucial wartime messengers. Moss emphasizes that pigeons were essential during the D-Day invasion due to radio silence protocols, and the celebrated pigeon Cher Ami saved imperiled soldiers during World War I. Moss notes that British forces even systematically killed Peregrine Falcons to protect pigeon communications, inadvertently contributing to the species' subsequent endangerment and near-extinction. 1869

Cristina Gomez discusses the latest findings on interstellar object 3I/ATLAS, including Dr. Avi Loeb's new theory that its jets are pulsating like a heartbeat every 16 hours, the mysterious data changes on NASA's JPL website after the Hill radius coincidence was discovered, and why hundreds of telescopes worldwide are now tracking this object as it heads toward Jupiter.To see the VIDEO of this episode, click or copy link - https://youtu.be/bCPe6UTMMwIVisit my website with International UFO News, Articles, Videos, and Podcast direct links -www.ufonews.co00:00 - 3I/ATLAS Pulsating Like A Heartbeat00:45 - The Jupiter 3I/ATLAS Trajectory01:55 - JPL Changed The 3I/ATLAS Data03:28 - The Perpendicular Object04:19 - 3I/ATLAS Pulsating Jets05:31 - 3I/ATLAS Natural Or Technological?07:00 - What The Data Could RevealBecome a supporter of this podcast: https://www.spreaker.com/podcast/strange-and-unexplained--5235662/support.

Dr. Suresh Durgam (Intra-Cellular Therapies, a Johnson & Johnson Company, Bedminster, NJ) joins AJP Audio to discuss a phase 3 randomized controlled trial looking at the use of the antipsychotic medication lumateperone as adjunctive to antidepressant therapy in the treatment of patients with major depressive disorder. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses the rest of the December issue of the Journal. 00:48   Durgam interview 03:09   Mechanism of action 04:44   Patient-reported outcomes 06:31   Immediate clinical implications 07:32   Limitations 08:08   Further research 09:25   Kalin interview 09:38   Durgam et al. 13:09   Lin et al. 17:22   Brodsky et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org

After graduating from Caltech with a degree in physics, Scott Sperling pursued computer science and ended up working in rocket science. He’s also been a Christian for decades and has applied his analytical mind to Bible study, especially on his website ScriptureStudies.com. In this interview I ask him about his paper, “A Hypothesis for the Mechanism of Bodily Resurrection” in which he explains how God can raise the dead on the basis of DNA and the neural connectome. He does not see any need for the existence of an immaterial soul or dualism to account for biblical resurrection.   Listen on Spotify   Listen on Apple Podcasts —— Links —— See Scott Sperling’s studies at his website where you can also download his paper. Support Restitutio by donating here Join our Facebook group, follow on X @RestitutioSF or Instagram @Sean.P.Finnegan Leave a 90 second voice message via SpeakPipe with questions or comments and we may play it out on the air Who is Sean Finnegan?  Read his bio here Get Finnegan’s book, Kingdom Journey to learn about God’s kingdom coming on earth as well as the story of how Christianity lost this pearl of great price. Get the transcript of this episode Intro music: Good Vibes by MBB Attribution-ShareAlike 3.0 Unported (CC BY-SA 3.0) Free Download / Stream: Music promoted by Audio Library.

Dietitians Aidan Muir and Torwen Eerkens unpack the role of bicarbonate soda as a supplement for athletic performance. They explore the mechanism, types of exercise which see a benefit, percentage improvement, risks and practical recommendations for incorporating bicarb your regime.     Time stamps (00:53) - Mechanism for Athletes (1:50) - Types of Exercise  (2:52) - Dosage & How to Take (3:53) - What Are the Risks?  (5:25) - Practical Recommendations for Navigating Risks (6:21) - Research on Running and Endurance Events  (8:18) - Research on Strength Performance (8:56) - Bicarb vs Beta Alanine (10:07) - When Do We Recommend This in Practice? WEBSITE:  https://www.idealnutrition.com.au/ PODCAST:  https://www.idealnutrition.com.au/podcast/ INSTAGRAM:  https://www.instagram.com/idealnutrition__/?hl=en Our dietitians

When 18-year-old Anna Kepner was found hidden under a bed inside a cruise ship cabin, the story immediately drew national attention — not because of what investigators discovered, but because of all the things they didn't. No intruder. No external threat. No clear cause of death. Just a 16-year-old stepsibling who now sits at the center of a legal and emotional storm. Tonight on Hidden Killers, we dig into the legal tensions surrounding this case — the gaps, the unknowns, the strict limitations of the juvenile system, and the uncomfortable reality that many of these answers may never become public. With attorney and former prosecutor Bob Motta, we explore every realistic scenario investigators must consider: accident, panic, trauma, a moment of fear that spiraled, an altercation without intent, a medical event mishandled, or an intentional act. The law doesn't get to pick the neat version — it has to test all of them. We also break down the implications of the stepson's claim that he “doesn't remember what happened.” Legally, that can indicate trauma, shock, dissociation, or a panic-response blackout — all of which dramatically complicate the question of charges. Because intent matters. Mechanism matters. And mental state matters. We look at why certain charges are possible, why some are unlikely, and why others — like premeditated murder — simply don't fit the known facts. And we explain the Fifth Amendment move by the stepmother: a headline-grabbing moment that creates more confusion than clarity. Most importantly, we dive into the biggest question: how does a case like this realistically end? A juvenile plea? Treatment? No charges? Or a sealed resolution the public will never see? This case is heartbreaking, confusing, and bound by legal blinders that make it even harder to understand. But tonight, we break down what the law actually says — not what the internet assumes. #AnnaKepner #CruiseCase #HiddenKillers #TrueCrimeToday #LegalBreakdown #JuvenileCase #BobMotta #CrimeAnalysis #JusticeSystem #InvestigationUpdate Want to comment and watch this podcast as a video? Check out our YouTube Channel. https://www.youtube.com/@hiddenkillerspod Instagram https://www.instagram.com/hiddenkillerspod/ Facebook https://www.facebook.com/hiddenkillerspod/ Tik-Tok https://www.tiktok.com/@hiddenkillerspod X Twitter https://x.com/tonybpod Listen Ad-Free On Apple Podcasts Here: https://podcasts.apple.com/us/podcast/true-crime-today-premium-plus-ad-free-advance-episode/id1705422872

When 18-year-old Anna Kepner was found hidden under a bed inside a cruise ship cabin, the story immediately drew national attention — not because of what investigators discovered, but because of all the things they didn't. No intruder. No external threat. No clear cause of death. Just a 16-year-old stepsibling who now sits at the center of a legal and emotional storm. Tonight on Hidden Killers, we dig into the legal tensions surrounding this case — the gaps, the unknowns, the strict limitations of the juvenile system, and the uncomfortable reality that many of these answers may never become public. With attorney and former prosecutor Bob Motta, we explore every realistic scenario investigators must consider: accident, panic, trauma, a moment of fear that spiraled, an altercation without intent, a medical event mishandled, or an intentional act. The law doesn't get to pick the neat version — it has to test all of them. We also break down the implications of the stepson's claim that he “doesn't remember what happened.” Legally, that can indicate trauma, shock, dissociation, or a panic-response blackout — all of which dramatically complicate the question of charges. Because intent matters. Mechanism matters. And mental state matters. We look at why certain charges are possible, why some are unlikely, and why others — like premeditated murder — simply don't fit the known facts. And we explain the Fifth Amendment move by the stepmother: a headline-grabbing moment that creates more confusion than clarity. Most importantly, we dive into the biggest question: how does a case like this realistically end? A juvenile plea? Treatment? No charges? Or a sealed resolution the public will never see? This case is heartbreaking, confusing, and bound by legal blinders that make it even harder to understand. But tonight, we break down what the law actually says — not what the internet assumes. #AnnaKepner #CruiseCase #HiddenKillers #TrueCrimeToday #LegalBreakdown #JuvenileCase #BobMotta #CrimeAnalysis #JusticeSystem #InvestigationUpdate Want to comment and watch this podcast as a video? Check out our YouTube Channel. https://www.youtube.com/@hiddenkillerspod Instagram https://www.instagram.com/hiddenkillerspod/ Facebook https://www.facebook.com/hiddenkillerspod/ Tik-Tok https://www.tiktok.com/@hiddenkillerspod X Twitter https://x.com/tonybpod Listen Ad-Free On Apple Podcasts Here: https://podcasts.apple.com/us/podcast/true-crime-today-premium-plus-ad-free-advance-episode/id1705422872

When 18-year-old Anna Kepner was found hidden under a bed inside a cruise ship cabin, the story immediately drew national attention — not because of what investigators discovered, but because of all the things they didn't. No intruder. No external threat. No clear cause of death. Just a 16-year-old stepsibling who now sits at the center of a legal and emotional storm. Tonight on Hidden Killers, we dig into the legal tensions surrounding this case — the gaps, the unknowns, the strict limitations of the juvenile system, and the uncomfortable reality that many of these answers may never become public. With attorney and former prosecutor Bob Motta, we explore every realistic scenario investigators must consider: accident, panic, trauma, a moment of fear that spiraled, an altercation without intent, a medical event mishandled, or an intentional act. The law doesn't get to pick the neat version — it has to test all of them. We also break down the implications of the stepson's claim that he “doesn't remember what happened.” Legally, that can indicate trauma, shock, dissociation, or a panic-response blackout — all of which dramatically complicate the question of charges. Because intent matters. Mechanism matters. And mental state matters. We look at why certain charges are possible, why some are unlikely, and why others — like premeditated murder — simply don't fit the known facts. And we explain the Fifth Amendment move by the stepmother: a headline-grabbing moment that creates more confusion than clarity. Most importantly, we dive into the biggest question: how does a case like this realistically end? A juvenile plea? Treatment? No charges? Or a sealed resolution the public will never see? This case is heartbreaking, confusing, and bound by legal blinders that make it even harder to understand. But tonight, we break down what the law actually says — not what the internet assumes. #AnnaKepner #CruiseCase #HiddenKillers #TrueCrimeToday #LegalBreakdown #JuvenileCase #BobMotta #CrimeAnalysis #JusticeSystem #InvestigationUpdate Want to comment and watch this podcast as a video? Check out our YouTube Channel. https://www.youtube.com/@hiddenkillerspod Instagram https://www.instagram.com/hiddenkillerspod/ Facebook https://www.facebook.com/hiddenkillerspod/ Tik-Tok https://www.tiktok.com/@hiddenkillerspod X Twitter https://x.com/tonybpod Listen Ad-Free On Apple Podcasts Here: https://podcasts.apple.com/us/podcast/true-crime-today-premium-plus-ad-free-advance-episode/id1705422872

In this discussion recorded in Belém, Brazil, we hear the perspective of Tyrone Scott, campaigner at War on Want, who was involved in the push for the Belém Action Mechanism for Just Transition that was established at the COP summit in Brazil in Nov. 2025. This was an important focus point for climate justice campaigners at the COP summit who were involved in actions and interventions around the event. Learn more about the context around this and the Belém Action Mechanism for Just Transition, here: https://climatenetwork.org/resource/discussion-paper-belem-action-mechanism-october-2025/ Learn more about War on Want here: https://waronwant.org

How we can use an output-based system to judge whether or not different kinds of technology achieve understanding or intelligence. Become a Member: https://danielmiessler.com/upgradeSee omnystudio.com/listener for privacy information.

A brutal incident where a woman gets hit by a truck leaves her with a multitude of injuries, most notably both of her legs bent into a position best described as "frog legs." She's in good spirits and her vitals are good, but her legs bent at that angle means that she cannot fit into our team's helicopter. How does our team get her legs back into place without causing further trauma or risking her stable vitals? Complicating factors is the extremely uneven ground because they're in a cow pasture and the risk of infection is extremely high because the team and the patient are surrounded by cow patties. There is no training for this exact scenario, so how does our team adapt and apply the training they have to this unique situation? This episode of AMPED digs in.   Interested in obtaining CE credit for this episode? Visit OnlineAscend.com to learn more. Listeners can purchase individual episode credits or subscribe to the Critical Care Review Bundle and gain access to all episode CE Credits.    We are joined by:   Aaron Botzow, NRP, FP-C     Drew Gill, BSN, RN, CEN     Michael Eastman DO   Click here to download this episode today! As always thanks for listening and fly safe! Hawnwan Moy MD FACEP FAEMS John Wilmas MD FACEP FAEMS Nyssa Hattaway, BA, BSN, RN, CEN, CPEN, CFRN

BUFFALO, NY – November 18, 2025 – A new #review was #published in Oncotarget (Volume 16) on November 14, 2025, titled “Mechanism of anticancer action of bifidobacterium: Insights from gut microbiota.” This review, led by first author Hoang Do and correspondent author Ashakumary Lakshmikuttyamma from Thomas Jefferson University, explores how bifidobacterium, a common probiotic found in the gut, may contribute to cancer prevention and therapy. By analyzing existing studies, the authors highlight the growing importance of gut health in cancer treatment and shed light on how bifidobacterium could complement standard cancer therapies. Bifidobacterium is widely known for promoting digestive health and is often included in fermented foods and dietary supplements. However, emerging evidence suggests it may also play a broader role in immune regulation and cancer defense. The review explains how certain strains of bifidobacterium may enhance the effectiveness of chemotherapy, radiation, and immunotherapy in cancers such as breast, lung, colorectal, and gastric cancers. According to the review, bifidobacterium influences cancer outcomes through several biological mechanisms. It helps regulate immune function by reducing inflammation and supporting the activity of immune cells that target tumors. For instance, strains like B. longum and B. breve have been shown to lower levels of harmful inflammatory markers and boost anti-inflammatory responses. These changes can make cancer treatments more effective while also reducing side effects. “Presence of Bifidobacterium breve in gut microbiota extended the median progression-free survival of NSCLC patients.” The review also discusses how bifidobacterium helps detoxify the body by breaking down cancer-causing compounds and limiting their ability to damage cells. In preclinical studies, the probiotic reduced the activity of enzymes that produce carcinogens and helped in converting food-based substances into cancer-fighting agents. Some strains were even found to suppress genes that promote tumor growth and increase molecules that trigger cancer cell death. The authors emphasize that diet plays a critical role in supporting the growth of bifidobacterium. Foods rich in dietary fiber, especially those containing inulin and oligosaccharides like garlic, onions, or leeks, can help increase its levels in the gut. This suggests that simple dietary changes could not only improve gut health but also support cancer prevention and treatment strategies. Although the review presents compelling evidence, the authors stress the need for more clinical trials to determine how different strains of bifidobacterium affect specific types of cancer. Personalized approaches may be necessary to match the right probiotic strains with individual treatment plans. As research continues to uncover the link between gut microbes and cancer, bifidobacterium stands out as a promising natural ally that could enhance the body's defenses and improve cancer treatment outcomes. DOI - https://doi.org/10.18632/oncotarget.28779 Correspondence to - Ashakumary Lakshmikuttyamma - axl025@jefferson.edu Abstract video - https://www.youtube.com/watch?v=KTWJDAN15lY Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28779 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

What if a molecule could help you live longer, sleep better, and feel more energised—without the hype?In this episode of the Health Up podcast, Anthony Hartcher chats with scientist and entrepreneur Chris Burres, co-founder of MyVitalC, about the groundbreaking molecule ESS60. Discovered in 1985 and backed by Nobel Prize-winning research, ESS60 has shown remarkable potential in longevity, energy, sleep quality, and cellular health.Chris shares:The surprising origin story behind his journey into health science (hint: it involves a Lamborghini)How ESS60 works inside the mitochondria to reduce oxidative stressReal-life testimonials, including recovery stories from pets and elite athletesThe science behind better sleep, improved focus, and enhanced recoveryHis top biohacks for living longer and better

Bisacodyl, commonly known by the brand name Dulcolax, is a stimulant laxative widely used for short-term relief of constipation and bowel preparation before procedures. It works by directly stimulating the enteric nerves in the colon, increasing peristalsis, and promoting bowel evacuation. Mechanism of Action:Bisacodyl acts primarily on the large intestine. It stimulates intestinal smooth muscle and alters water and electrolyte transport, increasing fluid accumulation in the bowel and triggering defecation. The result is a bowel movement typically within 6–12 hours orally or within 15–60 minutes when given rectally. Dosage Forms and Dosing:Bisacodyl is available as oral tablets (5 mg) and rectal suppositories (10 mg). Typical adult dosing is 5–15 mg by mouth once daily or 10 mg rectally as needed. It's often used for acute constipation, bowel prep, or to prevent straining in specific medical situations. Adverse Effects:Common side effects include abdominal cramping, diarrhea, and nausea. Chronic or excessive use may lead to electrolyte imbalances, dehydration, and laxative dependence. Drug Interactions and Monitoring:Concurrent use with antacids, proton pump inhibitors, or milk may cause premature dissolution of enteric-coated tablets, leading to gastric irritation. Monitoring for bowel regularity, hydration status, and signs of electrolyte imbalance is important—especially in elderly or debilitated patients.

Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comIn this fascinating episode, Dr. Gabrielle Lyon talks with neuroscientist Dr. Ben Rein, PhD (author of Why Brains Need Friends), about the science of social connection, emotion, and cognitive health. Dr. Rein, an expert in neurobiology and psychedelic research, reveals the cutting-edge studies that explain why loneliness is as damaging as smoking and how our digital world is affecting our brain's ability to connect.They discuss the neurochemistry of love, the controversial use of MDMA in therapy, and whether AI can ever truly replace human intimacy. This conversation provides an essential look at the biological drivers of happiness, performance, and long-term brain health.Chapter Markers:0:00 - MDMA (Molly): The History & Therapeutic Benefits 5:59 - The Legal Status of MDMA for PTSD 6:44 - The Safety and Effectiveness of MDMA in Clinical Trials 8:29 - PTSD (The Amygdala Alarm) 9:41 - How MDMA Soothes the Amygdala to Access Memory 11:42 - Is There an Alternative to MDMA? (Ketamine's Mechanism) 13:16 - Ketamine and Neuroplasticity for Depression 15:48 - Botox and Empathy: 18:12 - The Problem of Volume: How Screens Depersonalize Interaction 19:48 - The Virtual Disengagement Hypothesis Explained 25:00 - Defining Cognitive and Emotional Empathy 29:43 - MDMA's Link to Serotonin & Social Reward 31:04 - Do SSRIs Have Pro-Social Effects? 36:10 - The Science of Likability and "Easy to Read" Faces 40:10 - Top 3 Ways to Be More Likable49:49 - The Likability Gap: Why You Underestimate How Well-Liked You Are 56:59 - The Neurobiology of Oxytocin, Dopamine, and Serotonin1:09:23 - The Goldilocks Zone of Empathy 1:15:58 - Narcolepsy 1:18:16 - Alcohol: Why the Neurotoxin is Bad for Brain Health 1:21:47 - Exercise and Neurogenesis1:22:27 - Sex, Orgasm, and Oxytocin Release 1:25:06 - Oxytocin During Childbirth Who is Ben Rein:Dr. Ben Rein is an award-winning neuroscientist and Chief Science Officer of the Mind Science Foundation, where he supports early-career researchers in neuroscience. He earned his PhD from SUNY Buffalo and completed postdoctoral training at Stanford University, publishing over 20 peer-reviewed papers on autism, empathy, MDMA, and digital behavior. Recognized by the NIH, the Society for Neuroscience, and Sigma Xi, he also serves as a scientific advisor to more than 20 organizations. With over one million followers and 75 million video views, Dr. Rein is celebrated for making neuroscience accessible to the public and has been featured by outlets such as Good Morning America, ABC News, and PopularMechanics.Thank you to our sponsors:BodyHealth: Use code LYON20 to get 20% off your first order https://www.bodyhealthaffiliates.com/73L4QL3/7XDN2/BON CHARGE Holiday Sale https://boncharge.com for 25% off Pique 20% off for life: https://Piquelife.com/DRLYONFind Ben Rein at: Website: https://www.benrein.com/Instagram: https://www.instagram.com/dr.benrein/#TikTok: https://www.tiktok.com/@dr.benrein?lang=enFacebook:

In today's episode, we discuss the mechanism by which upper cervical subluxations cause nerve pressure and dysfunction. This is an important piece of the assessment if we are going to create a proper correction. 

Unpacking market volatility, stablecoins, and Kraken's strategy with Co-CEO David Ripley. Kraken Co-CEO David Ripley joins CoinDesk's Jennifer Sanasie and Andy Baehr to discuss the firm's record-breaking Q3 growth and its strategy to merge traditional finance with crypto by moving into futures and equities trading. Ripley highlights the "network effect" that has made stablecoins the default settlement currency for exchanges and integrated crypto businesses. He also addresses the compression of Bitcoin volatility and how Kraken is catering to both seasoned individual pro traders and the broader, derivatives-shy retail consumer base. - Break the cycle of exploitation. Break down the barriers to truth. Break into the next generation of privacy. Break Free. Free to scroll without being monetized. Free from censorship. Freedom without fear. We deserve more when it comes to privacy. Experience the next generation of blockchain that is private and inclusive by design. Break free with Midnight, visit ⁠⁠⁠⁠⁠⁠midnight.network/break-free⁠⁠⁠⁠⁠⁠ - OwlTing (Nasdaq: OWLS) is building invisible rails for global payments. With OwlPay, businesses and users can bridge fiat and stablecoins, send money instantly across borders, and access stablecoin checkout at lower costs. Licensed worldwide, OwlTing delivers secure, compliant, and regulated infrastructure for the digital economy. Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠owlting.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. - Genius Group has partnered with CoinDesk for Bitcoin Treasury Month, launching the Genius x CoinDesk Quest. Participants can join the Bitcoin Academy, complete free microcourses from experts like Natalie Brunell and Saifedean Ammous, and enter to win 1,000,000 GEMs (worth 1 BTC) promoting bitcoin education and adoption. Learn more at: ⁠https://www.geniusgroup.ai/coindesk-bitcoin-treasury-month/⁠ - This episode was hosted by Jennifer Sanasie and Andy Baehr.

Unpacking market volatility, stablecoins, and Kraken's strategy with Co-CEO David Ripley. Kraken Co-CEO David Ripley joins CoinDesk's Jennifer Sanasie and Andy Baehr to discuss the firm's record-breaking Q3 growth and its strategy to merge traditional finance with crypto by moving into futures and equities trading. Ripley highlights the "network effect" that has made stablecoins the default settlement currency for exchanges and integrated crypto businesses. He also addresses the compression of Bitcoin volatility and how Kraken is catering to both seasoned individual pro traders and the broader, derivatives-shy retail consumer base. - Break the cycle of exploitation. Break down the barriers to truth. Break into the next generation of privacy. Break Free. Free to scroll without being monetized. Free from censorship. Freedom without fear. We deserve more when it comes to privacy. Experience the next generation of blockchain that is private and inclusive by design. Break free with Midnight, visit ⁠⁠⁠⁠⁠⁠midnight.network/break-free⁠⁠⁠⁠⁠⁠ - OwlTing (Nasdaq: OWLS) is building invisible rails for global payments. With OwlPay, businesses and users can bridge fiat and stablecoins, send money instantly across borders, and access stablecoin checkout at lower costs. Licensed worldwide, OwlTing delivers secure, compliant, and regulated infrastructure for the digital economy. Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠owlting.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. - Genius Group has partnered with CoinDesk for Bitcoin Treasury Month, launching the Genius x CoinDesk Quest. Participants can join the Bitcoin Academy, complete free microcourses from experts like Natalie Brunell and Saifedean Ammous, and enter to win 1,000,000 GEMs (worth 1 BTC) promoting bitcoin education and adoption. Learn more at: ⁠https://www.geniusgroup.ai/coindesk-bitcoin-treasury-month/⁠ - This episode was hosted by Jennifer Sanasie and Andy Baehr.

Unpacking market volatility, stablecoins, and Kraken's strategy with Co-CEO David Ripley. Kraken Co-CEO David Ripley joins CoinDesk's Jennifer Sanasie and Andy Baehr to discuss the firm's record-breaking Q3 growth and its strategy to merge traditional finance with crypto by moving into futures and equities trading. Ripley highlights the "network effect" that has made stablecoins the default settlement currency for exchanges and integrated crypto businesses. He also addresses the compression of Bitcoin volatility and how Kraken is catering to both seasoned individual pro traders and the broader, derivatives-shy retail consumer base. - Break the cycle of exploitation. Break down the barriers to truth. Break into the next generation of privacy. Break Free. Free to scroll without being monetized. Free from censorship. Freedom without fear. We deserve more when it comes to privacy. Experience the next generation of blockchain that is private and inclusive by design. Break free with Midnight, visit ⁠⁠⁠⁠⁠⁠midnight.network/break-free⁠⁠⁠⁠⁠⁠ - OwlTing (Nasdaq: OWLS) is building invisible rails for global payments. With OwlPay, businesses and users can bridge fiat and stablecoins, send money instantly across borders, and access stablecoin checkout at lower costs. Licensed worldwide, OwlTing delivers secure, compliant, and regulated infrastructure for the digital economy. Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠owlting.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. - Genius Group has partnered with CoinDesk for Bitcoin Treasury Month, launching the Genius x CoinDesk Quest. Participants can join the Bitcoin Academy, complete free microcourses from experts like Natalie Brunell and Saifedean Ammous, and enter to win 1,000,000 GEMs (worth 1 BTC) promoting bitcoin education and adoption. Learn more at: ⁠https://www.geniusgroup.ai/coindesk-bitcoin-treasury-month/⁠ - This episode was hosted by Jennifer Sanasie and Andy Baehr.

Regenerative aesthetics continues to evolve—and polynucleotides are taking center stage. These powerful bioactive molecules are changing the game when it comes to collagen stimulation, skin healing, and true rejuvenation.

Humanity has long misunderstood fertility. Part 76 of The Story of Creation is a profound exploration where Michelle reveals that fertility energy is not merely physical—it is the universal mechanism of creation itself. Every idea, curiosity, and intention you hold carries the potential to shape reality. From a universal creation perspective, matter is the final 1–2% of a much larger energetic equation. Everything begins with vibration. When you understand energy before matter, you begin to see that your life, your fulfillment, and even your purpose unfold through curiosity and intention. Michelle uncovers how the human brain has been conditioned to seek satisfaction in the physical, mistaking fleeting pleasure for creation. Yet, true fertility—the energy of existence—comes from your soul's vibration expanding beyond limitation. Through this revelation, you'll understand how human potential is born from freedom, curiosity, and the courage to explore who you are without fear. This episode dismantles the illusion that fertility is limited to reproduction. Instead, it reveals that every aspect of your life—your passions, projects, relationships, and ideas—exists as a reflection of your spiritual evolution. Fertility is the process by which you, as a Creator, bring your inner world to life. Learn how to transform shame into wisdom, rediscover fulfillment through energetic awareness, and understand that all information in existence—past, present, and future—is available through vibration. The history of humanity and existence is not lost; it is written in energy, encoded in your DNA, waiting to be remembered. Watch this exploration to reconnect with the universal truth of who you are: a living manifestation of the Creator's original intention, here to evolve consciousness and restore balance to existence through your participation in creation itself. 0:00 – The Foundation of Universal Creation 2:05 – Understanding Fertility Energy Beyond the Physical 3:50 – How Beliefs Shape Reality and Creation 6:01 – Fertility as the Mechanism of Manifestation 7:33 – The Energy That Creates Matter 10:08 – Misunderstanding Sex and the True Nature of Fertility: The Vortex of Creation Explained 12:10 – Freedom, Curiosity, and Fulfillment 13:28 – Reconnecting to Your Creative Power 14:16 – Why Depression and Anxiety Disconnect You from Creation 15:01 – Curiosity as the Catalyst of Evolution 19:19 – Shame, Secrets, and Hidden Wisdom 20:43 – Energy Holds All Information in Existence 26:33 – Creating Your Legacy 31:46 – Human Potential and the Future of Evolution ✨ Join Michelle and the Universal Council to explore the profound truth of existence, your role in evolution, and the power within your soul. Top Keywords: Fertility, Universal truth, soul alignment, consciousness evolution, human origins, spiritual awakening, self-awareness, universal perspective, creation mechanics, authentic human podcast, life purpose, reverence, humanity's evolution, cosmic power, inner fulfillment, universal communication. Discover more at: michellevickers.com/community Michelle Vickers is a researcher, communicator, and explorer of creation, existence, and evolution. Through her direct connection with the Creator and Universal Beings, Michelle translates universal communication into practical understanding—bridging science and spirituality to reveal the hidden mechanics of consciousness. Her work empowers humanity to remember the truth of creation and access the full potential of their soul, restoring integrity, purpose, and alignment between energy and matter. ➤ Subscribe to The Authentic Human Podcast to dive deeper into universal truth. ➤ Comment below: What is your deepest question you've never asked — start now.

Are supplements helping you — or wasting your money? In this episode of The Exam Room Podcast, Dr. Gemma Newman joins Chuck Carroll to break down the science, myths, and marketing behind the multibillion-dollar supplement industry. Discover which supplements are truly worth taking, which can be harmful in excess, and how to build better health through a whole-food, plant-based diet. Whether you're taking vitamin B12, vitamin D, omega-3, or a daily multivitamin, Dr. Newman explains how to personalize your nutrition safely and effectively. In This Episode: - The truth about supplements and what's actually backed by science - Why multivitamins don't extend lifespan — and can sometimes harm your health - How to get vitamin B12 safely - The risks of "natural" supplements - The difference between fish oil vs. algae-based omega-3s - Dr. Newman's SMART method: Science, Mechanism, Aim, Risk vs. Benefit, Tracking - How to spot fake supplement ads and AI deepfakes online Known as The Plant Power Doctor, Dr. Newman is a respected physician and lifestyle medicine expert helping patients reverse chronic disease through evidence-based nutrition and lifestyle change.

In Podcast 61, I sit with Dr. Karen Hurd to discuss HRT.Episode Focus: Re-examining the risks of Hormone Replacement Therapy (HRT) in light of new scientific rhetoric, The biological mechanism of hormonal damage, and the power of lifestyle in navigating menopause.1. The Core Scientific Risk: DNA DamageDr. Hurd challenges the idea that "bioidentical" hormones are inherently safer than synthetic ones.The Mechanism of Action: Hormones (both endogenous/innate and exogenous/prescribed) are very small molecules known scientifically as nuclear receptors.Crossing Barriers: These molecules are so tiny that they can bypass normal cellular defenses by diffusing directly through the cell membrane (plasma membrane) and the nuclear envelope.The DNA Barrage: Once inside the nucleus, the hormone-transcription factor complex randomly attaches to the DNA3. This is not a one-time event; a daily pill or patch creates a constant barrage on the nuclear envelope.Mutating Genes: If this random attachment occurs at a critical site, such as the P53 gene (often affected in nearly 50% of hormonally receptive cancers) 5, it can disable the cell's stop mechanism (stop codon)6. The damaged cell then reproduces daughter cells carrying the same mutation, leading to tumors.The Power of Diet and LifestyleThe Natural Menopause: Menopausal symptoms (bone loss, brain fog, hot flashes) are often the result of entering menopause in a non-healthy stateEstrogen Drivers: Hormones are naturally produced, but their excess can be driven by lifestyle. Caffeine is a more powerful driver of estrogen production than sugar.Adrenal Role: The adrenal glands are meant to take over producing weaker, protective estrogens after menopause16. Stressing the adrenals with caffeine, sugar, and over-exercising diverts resources away from hormone production, leading to symptoms like vaginal atrophy and hot flashes.The Bean Protocol Solution: Eating soluble fiber (like beans) does not stop innate hormone production; rather, the fiber acts by carrying out what the liver dumps into the gut.. This prevents the excessive recycling (up to 72 times daily) of hormones, allowing the body to naturally bring elevated estrogen levels back down to a safe, post-menopausal levelYou can learn more about working with Karen Hurd at www.karenhurd.comand you can learn more about my courses and working with me at www.youregreat.comWishing you well on your human journey.X

The PREVENT score in hypertension, GLP-1 mechanism of action in cardiovascular disease, CAD type and statin benefit, and the problem with hospitalization endpoints in HF trials are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Is the PREVENT Calculator Best for Determining CVD Risk? Insights From a Post Hoc Analysis of SPRINT Trial https://www.medscape.com/viewarticle/prevent-calculator-best-determining-cvd-risk-insights-post-2025a1000svo PREVENT Calculator https://doi.org/10.1016/j.jacc.2025.07.037 SPRINT Trial https://www.nejm.org/doi/full/10.1056/NEJMoa1511939 II GLP-1 Mechanism of Action in CV Disease Analysis of SELECT Trial 10.1016/S0140-6736(25)01375-3 External Link SELECT trial https://www.nejm.org/doi/full/10.1056/NEJMoa2307563 III Statins and CAD Phenotype on CTA and Outcomes Interactions Between Statin Use, CAD Phenotypes on CTA  https://www.jacc.org/doi/10.1016/j.jcmg.2025.05.018 Statin Use for Primary Prevention of CVD https://jamanetwork.com/journals/jama/fullarticle/2795522 IV HHF Endpoints in Heart Failure Trials The Problem with Hospitalization Endpoints in HF Trials https://onlinelibrary.wiley.com/doi/10.1002/ejhf.70070 You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net

Straight out of college, today's guest wanted to make an impact on the African continent. For him, the best way to do this was through policy or the work of a nonprofit. But early into that work, it was the pull of business and its potential to drive social value that pulled him in. Today's guest, David Ellis, is the founder and CEO of Hatch Africa, a company seeking to bring a new business model to sub-Saharan Africa to, in their words, bring eggs and chickens to every household. Special Guest: David Ellis.

Public RSS Feeds vs Private RSS Feeds for Best Podcast SEO Distribution Practices with Favour Obasi-Ike | Sign up for exclusive SEO insights.In this podcast episode, Favour provides an extensive comparison between public podcast RSS feeds and private podcast RSS feeds, offering guidance on how to choose the appropriate option for one's needs, particularly for business growth. A public podcast is openly accessible on various platforms and directories like Apple Podcasts and Spotify, serving as a powerful tool for brand building, content marketing, and increasing accessibility. Conversely, a private podcast is characterized by requiring authentication for access, making it suitable for exclusive content, internal corporate training, or paid subscription communities, with platforms like Supercast and Hello Audio recommended for this purpose. Favour stresses that consistent content publication and maximizing RSS feed distribution to various directories are crucial for public podcast success, while noting that starting with a public podcast is often advisable before transitioning to a private, often monetized, model.The Public RSS Feed: Maximizing Reach and DiscoverabilityA public podcast RSS feed is a publicly listed show available on third-party platforms and directories. It is designed for open access and broad distribution.• Definition: A public feed is accessible to anyone on podcast players and websites without requiring a login or payment. It operates on a one-to-many distribution model, where a single RSS feed from a hosting platform is submitted to numerous podcast directories.• Analogy: The structure is comparable to a website, which has a backend hosting provider (e.g., GoDaddy, Hostinger) and a front-facing content management system (CMS) or website that users interact with. In podcasting, the hosting platform holds the audio files, and the directories (players) make them accessible to listeners.• Mechanism of Reach: The key to a public podcast's success is submitting its RSS feed to as many directories as possible. Each directory is a separate website or application, and being listed on 30 different players means 30 distinct online entities are linking back to the podcast, significantly enhancing its digital footprint and discoverability.The Private RSS Feed: Monetization and ExclusivityA private podcast RSS feed is intentionally not listed on public directories and is structured to control access.• Definition: A private feed is ineligible for public listing because it requires authentication—a user must sign up, log in, or pay to access the content. This creates a secure and exclusive listening experience.• Analogy: This model is comparable to subscription-based streaming services like Netflix or Amazon Prime. Users pay a fee to access a database of proprietary content. A private podcast operates on the same principle, offering exclusive audio or video content to a select audience.• Mechanism of Access: Access is granted only after a specific action is taken by the user, typically involving payment or registration. This makes it a powerful tool for delivering premium content, courses, internal communications, or community-specific updates.--------------------------------------------------------------------------------Next Steps for Digital Marketing + SEO Services:>> ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Need SEO Services? 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John Batchelor 09-03 segment 15.mp3 Guest: Janatyn Sayeh from the Foundation for Defense of Democracies. Iran's Nuclear Dilemma and Regional Threats Janatyn Sayeh discusses the looming snapback mechanism of the 2015 JCPOA, which could reinstate UN sanctions on Iran if it fails to comply with demands. Iran's non-compliance has its currency hitting new lows, yet Tehran threatens regional war and exiting the NPT if sanctions return. Sayeh notes Iran seeks rearmament, primarily from China, with Belarus and North Korea acting as potential intermediaries for Russian weapons. 1852 TEHRAN