Podcasts about Mechanism

In today's episode, we begin our exploration of Chapter 5 on the Mechanism of Vertebral Subluxation.   We will begin by looking at the normal structure and function of the intervertebral disc and how it works in the ideal situation.  

John Batchelor 09-03 segment 15.mp3 Guest: Janatyn Sayeh from the Foundation for Defense of Democracies. Iran's Nuclear Dilemma and Regional Threats Janatyn Sayeh discusses the looming snapback mechanism of the 2015 JCPOA, which could reinstate UN sanctions on Iran if it fails to comply with demands. Iran's non-compliance has its currency hitting new lows, yet Tehran threatens regional war and exiting the NPT if sanctions return. Sayeh notes Iran seeks rearmament, primarily from China, with Belarus and North Korea acting as potential intermediaries for Russian weapons. 1852 TEHRAN

We get deep with the Wistful Bard himself Ray Flanagan as he shares the lessons and perspectives he's gained over 11 years as a full-time musician.Ray is deeply woven into Cleveland's music community. Catch him hosting jam nights every Tuesday at Mercury Music Lounge, or see his collaboration sets the last Monday of the month at The Winchester.His new album "My Mind is Burning Up" drops next spring, but you can get early access by DMing him for a private link. In the meantime, dive into his extensive discography on all streaming platforms. THANK YOU RAY.SONGS PERFORMED:Someone Else's ShoesI Love the NighttimeAshesWe're DoomedSimple Stuff I GuessPerformance mixed/mastered by Jake ConderCONNECT WITH RAY:https://www.instagram.com/rayaflanagan/https://rayflanagan.bandcamp.com/music----...if you have a sec - please leave us a rating/ review on Apple/ Spotify!Apple: https://podcasts.apple.com/us/podcast/locle-grown/id1619510885Spotify: https://open.spotify.com/show/6OpyraRZDUqf6h8ZKq8KE3?si=75f15ec563714a6cApply to be a guest: https://www.loclegrown.com/past-guests-and-how-to-apply Circle K is a proud sponsor of LoCLE Grown! Download the Inner Circle App today to get .25 cents per gallon off your first 5 fill ups and 5 free drinks! Learn more here: https://www.circlek.com/inner-circleCircle K Inner Circle iPhone App: https://apps.apple.com/us/app/circle-k/id1592397814Circle K Inner Circle  Google Play App: https://play.google.com/store/apps/details?id=com.circlek.gmap.na&hl=en&gl=US&pli=1

Welcome to PsychEd, the psychiatry podcast for medical learners, by medical learners. This episode covers exercise as a treatment for depression. Our guest for this episode is Dr. Nicholas Fabiano, a third-year psychiatry resident at the University of Ottawa. His research focuses on the overlap between mental and physical health, particularly lifestyle measures that can be used to improve mental health, including exercise, diet, and sleep.The learning objectives for this episode are as follows:Understand the evidence supporting the antidepressant effects of exercise Explore the mechanisms underlying the benefits of exerciseLearn how to prescribe exercise as a treatment for depressionIdentify the risks and caveats of prescribing exercise for depressionGuest: Dr. Nicholas Fabiano (PGY3)Hosts: Dr. Wendy MacMillan-Wang (PGY4) and Dr. Angad Singh (PGY1)Audio Editing: Dr. Angad Singh (PGY1)Timestamps:(2:55) Origins of the interest in exercise(6:22) Evidence of antidepressant effects(14:05) Considerations in special populations(18:00) Overlap of mental and physical health(20:37) Mechanism of action(26:18) Exercise prescription(33:10) Exercise as addiction and self-harm(36:42) Counselling and mitigating harm(39:30) Combining with other lifestyle interventions(41:41) Evidence for other mental illnessesReferences:Fabiano N, Gupta A, Fiedorowicz JG, Firth J, Stubbs B, Vancampfort D, Schuch FB, Carr LJ, Solmi M. The effect of exercise on suicidal ideation and behaviors: A systematic review and meta-analysis of randomized controlled trials. Journal of affective disorders. 2023 Jun 1;330:355-66.Fabiano, N., Puder, D., & Stubbs, B. (2024). The evidence is clear, exercise is not better than antidepressants or therapy: it is crucial to communicate science honestly. Journal of Physical Activity and Health, 1(aop), 1-2.Heissel, A., Heinen, D., Brokmeier, L. L., Skarabis, N., Kangas, M., Vancampfort, D., ... & Schuch, F. (2023). Exercise as medicine for depressive symptoms? A systematic review and meta-analysis with meta-regression. British journal of sports medicine, 57(16), 1049-1057.Hird, E. J., Slanina-Davies, A., Lewis, G., Hamer, M., & Roiser, J. P. (2024). From movement to motivation: a proposed framework to understand the antidepressant effect of exercise. Translational Psychiatry, 14(1), 273.Verhoeven, J. E., Han, L. K., Lever-van Milligen, B. A., Hu, M. X., Révész, D., Hoogendoorn, A. W., ... & Penninx, B. W. (2023). Antidepressants or running therapy: Comparing effects on mental and physical health in patients with depression and anxiety disorders. Journal of affective disorders, 329, 19-29.For more PsychEd, follow us on Instagram (@psyched.podcast),  Facebook (PsychEd Podcast), X (@psychedpodcast), and Bluesky (@psychedpodcast.bsky.social‬). You can email us at psychedpodcast@gmail.com and visit our website at psychedpodcast.org.

In this episode, Dr. Jockers takes a deep dive into the shocking truth about Ozempic and other GLP-1 weight loss drugs. You'll hear how these medications actually work in the body, why they cause rapid weight loss for some, and what doctors often leave out about their risks. The discussion is packed with insights you won't want to miss.   You'll also learn about the real side effects—ranging from digestive distress to more dangerous issues like thyroid cancer and kidney failure—that affect nearly one in five people taking these drugs. Dr. Jockers breaks down the science in plain language so you can make informed choices.   And if you're wondering whether there's a safer way to get the same results, you'll discover how protein, fiber, and healthy fats can mimic the appetite-regulating effects of Ozempic. These lifestyle strategies not only reduce cravings but also improve long-term health without the side effects.     In This Episode:  00:00 Introduction to Weight Loss Study 00:27 Welcome and Episode Overview 01:00 Exploring GLP-1 Agonists 03:51 Deep Dive into Weight Loss Medications 04:33 Mechanism of GLP-1 Drugs 09:21 Clinical Research Findings 12:30 Side Effects and Risks 14:08 Natural Alternatives to Medications 17:53 Conclusion and Final Thoughts     Are swollen legs or ankles slowing you down? Discover the power of Lymph System Support by Pure Health Research. Crafted with natural ingredients like dandelion extract, burdock root, and bromelain, this formula unclogs your lymphatic system, reducing swelling and supporting a healthy inflammatory response.   As a special offer, try Lymph System Support risk-free today and receive a complimentary bottle of curcumin extract. Visit GetLymphHelp.com/jockers to claim yours now. Say hello to renewed vitality and goodbye to discomfort!   Hair loss isn't just about age—it's about hair follicles getting stuck. AnaGain Nu by Purality Health uses a pea sprout extract clinically shown to reactivate follicles and boost regrowth. With their micelle liposomal delivery, your body absorbs it fast and effectively. Try it risk-free with a 180-day money-back guarantee and get a buy-one-get-one-free deal at RenewYourHair.com/DRJ.     “Ozempic lowers blood sugar, but it may also raise your risk of thyroid cancer, pancreatitis, and kidney failure.”  ~ Dr. Jockers   Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio   Resources: GetLymphHelp.com/jockers Visit https://renewyourhair.com/drj   Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/ 

What if telepathy isn't fantasy, but an undiscovered frontier of biophysics? In this conversation, Helené Wahbeh of the Institute of Noetic Sciences joins us to explore how mind-to-mind communication could be studied through neuroscience, quantum theory, and consciousness research. We're not obsessed with whether it's real — we're asking how it would work if it were. A tightrope the edge of what's known, where psi phenomena meets mechanism and physics.PATREON https://www.patreon.com/c/demystifysciPARADIGM DRIFThttps://demystifysci.com/paradigm-drift-showOUR HOMEBREWED MUSIC Check out our band's new album:https://secretaryofnature.bandcamp.com/album/everything-is-so-good-hereVinyl pre-orders available now: https://buy.stripe.com/14A5kC3Od5d21Ms7zPdEs09Follow Helenê & IONS at https://noetic.org00:00 Go! Intro to Psi Phenomena 00:05:00 Media Influence on Psi Research 00:06:12 Dr. Wahbeh's Journey into Psi Research 00:19:00 Historical Context of Channeling Practices 00:24:54 Medicalization and Altered States 00:26:04 Spirit Influence on Mental Health 00:29:27 Historical Context of Spiritualism 00:32:56 Power and Intermediaries in Religion 00:35:12 Personal Experiences with Spirituality 00:39:50 The Nature of Prophecy and Free Will 00:42:00 Interpretation and Influence of Messages 00:47:30 Interconnectedness and Source of Information 00:49:33 Physics vs. Spiritual Experience 00:50:14 Importance of Rigorous Evidence in Telepathy Studies 00:53:37 Controlled Studies vs. Anecdotal Evidence 00:56:43 Challenges of Proving Paranormal Phenomena 00:59:38 Scientific Validity of Psychic Abilities 01:05:04 Emotional Context in Psychic Experiences 01:11:10 Practical Applications and Future of Psychic Research 01:13:21 Exploring Mechanisms of Telepathy 01:21:04 Instrumentalization of Mental Phenomena 01:32:04 Psychokinesis and Random Number Generators 01:36:52 Non-Physical Mechanisms of Interaction 01:37:40 Exploring Physical vs. Non-Physical Mechanisms 01:42:00 Philosophical Debate on Mechanism and Consciousness 01:49:30 Future of Mechanistic Understanding 01:58:30 Imagining Intentionality in Interconnected Fields 02:01:56 Exploring Consciousness Models 02:05:50 Interconnectedness and Humility in Understanding 02:09:43 Transcendent Experiences and Science 02:13:21 Physics and Mysticism: Distinct Yet Connected 02:22:00 Music, Emotion, and Scientific Inquiry 02:25:11 Exploring Diverse Worldviews 02:27:08 Speculating on Telepathy's Impact 02:31:43 Navigating Uncertainty and Truth 02:34:03 Embracing Collaboration for Future Insights#Consciousness, #Telepathy, #TheoreticalPhysics, #QuantumBiology, #neuroscience , #psi , #mindsciences , #NoeticSciences, #consciousness , #brainpower , #psychicenergy, #bigquestions #philosophypodcast , #sciencepodcast, #longformpodcast ABOUS US: Anastasia completed her PhD studying bioelectricity at Columbia University. When not talking to brilliant people or making movies, she spends her time painting, reading, and guiding backcountry excursions. Shilo also did his PhD at Columbia studying the elastic properties of molecular water. When he's not in the film studio, he's exploring sound in music. They are both freelance professors at various universities.

In this episode of Nuggets On The Go, Melvin from PropertyLimBrothers presents a strategic update on the evolving Singapore property market, focusing on the shift into a sellers market from 2025 to 2027. As interest rates begin to trend downward, Melvin explains why a low interest rate environment will favour asset appreciation and increase buyer demand—ultimately strengthening the position of property owners. He also cautions against premature refinancing, predicting even lower rates ahead.   Learn how Melvin's NSA (Next Stronger Asset) framework can help buyers and investors reposition wisely by upgrading from weaker to stronger assets. He also touches on the broader economic context—liquidity injections, potential Fed rate cuts, and capital flow from equities and crypto into real estate—painting a detailed picture of upcoming opportunities and risks.   If you're considering switching properties or building a portfolio in the current cycle, this episode offers grounded perspectives and timely strategy. An essential listen for those working through timing moves in a shifting market.   0:00 - Intro 0:48 - Episode Outline 0:53 - Important News in September 1:27 - Mechanism for interest rate reduction 2:04 - What Happens When There's Injection of Money Supply in the Market? 2:19 - M2 Money Supply 3:17 - Interest Rate Cuts Forecast 4:26 - Identifying Seller's Market 6:00 - Identifying Buyer's Market 6:36 - How To Switch Your Property in a Seller's Market? 8:19 - Explaining Next Stronger Asset 9:41 - What To Do When Moving to the Next Stronger Asset? 10:42 - What Might Happen to the Equities Market 11:33 - Rates Cuts Relative to Property Price Index 12:31 - Will New Cooling Measures Be Introduced? 13:23 - Some Charts For You 15:27 - Should I Be Worried About the Market Movements? 16:50 - Final Thoughts

Vilazodone (brand name Viibryd) is an antidepressant with a unique pharmacologic profile compared to most other agents in the SSRI class. While not a first-line choice for every patient, understanding its mechanism, adverse effects, and interaction profile is essential for optimizing therapy and preventing downstream prescribing problems. Mechanism of ActionVilazodone is classified as a selective serotonin reuptake inhibitor (SSRI) and a partial agonist at the 5-HT1A receptor. The SSRI activity increases synaptic serotonin by blocking the serotonin transporter, while partial agonism at 5-HT1A receptors may contribute to antidepressant effects and potentially reduce certain SSRI-associated adverse effects (though clinical evidence for this benefit is mixed). Adverse Effects GI effects – diarrhea, nausea, and vomiting are frequent early in therapy. Taking the medication with food can help minimize these. Insomnia – often dose-related; morning dosing may help. Sexual dysfunction – may be slightly lower than with some SSRIs but still present. Serotonin syndrome – rare but serious, particularly if combined with other serotonergic drugs. Discontinuation syndrome – abrupt cessation can lead to dizziness, irritability, and flu-like symptoms. Drug InteractionsVilazodone is primarily metabolized by CYP3A4. This means: CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin, ritonavir) can increase vilazodone concentrations, potentially worsening side effects—dose reductions may be required. CYP3A4 inducers (e.g., carbamazepine, rifampin, St. John's Wort) can lower drug levels, reducing effectiveness. Other serotonergic agents (e.g., triptans, SNRIs, MAOIs, tramadol, linezolid) increase the risk of serotonin syndrome. Antiplatelets and anticoagulants – SSRIs can impair platelet aggregation, increasing bleeding risk when combined with aspirin, NSAIDs, or warfarin. Prescribing Cascade ExamplesVilazodone's adverse effects can easily lead to unnecessary prescriptions if side effects aren't recognized: GI upset → Acid suppression therapy – Diarrhea or nausea prompts the addition of proton pump inhibitors or antiemetics, instead of adjusting vilazodone dose or timing. Insomnia → Hypnotic initiation – Trouble sleeping results in adding zolpidem or trazodone, without reassessing morning dosing or vilazodone's role. Sexual dysfunction → PDE5 inhibitor prescription – Erectile dysfunction leads to sildenafil use, when the root cause is vilazodone's serotonergic activity. Vilazodone's combination of SSRI and 5-HT1A partial agonist activity makes it somewhat distinct, but its side effect profile and interactions require the same careful monitoring as other antidepressants. Healthcare professionals can play a key role in catching early signs of adverse effects, preventing prescribing cascades, and ensuring drug–drug interactions are managed appropriately.

Your life runs on an invisible engine: your self-image. In this deep dive into Maxwell Maltz's New Psycho-Cybernetics, we uncover how your brain can't tell the difference between real and imagined, why failure is just feedback, and how visualization hijacks your nervous system to create success—or sabotage it.From childhood coding to perfectionism, scars that reshape identity, and the hidden hypnosis we're all still living in, this breakdown reveals how to reprogram the mental mechanism driving your reality.By the end, you'll know how to engineer happiness, free yourself from destructive patterns, and tap into the same internal system that athletes, creators, and high achievers use to perform at their peak.This isn't motivation. It's mental engineering.

Fibrodysplasia ossificans progressiva (FOP) is a severely disabling myopathy in which extraskeletal bone forms and accumulates over time within muscles and soft tissues.1,2 Here's what we know so far about the mechanisms of heterotopic ossification in patients with FOP. References: Kaplan FS et al. Best Pract Res Clin Rheumatol 2008;22:191–205. Pignolo RJ et al. Orphanet J Rare Dis 2011;6:80. © 2025 Ipsen Biopharmaceuticals Inc. All rights reserved. ALLSC-US-001927 | August 2025

Hey now, Cabalists! The gang is back and fired up for another episode of The Cabal! Tony's dealing with his dog's unfortunate bout of diarrhea, Chris went out to see Weird Al, and the crew hit the table with a pile of great new games including Above and Below Haunted, Ark Nova: Marine Worlds, El Burro, Heat Pedal to the Metal, Moon Colony Bloodbath, and feature Shackleton Base by Fabio Lopiano and Nestore Mangone, published by Sorry We Are French. After Tony T delivers his always-popular News segment, the gang dives into a discussion on the vital connection between theme and mechanisms in board games. Above and Below Haunted: 00:09:41, Ark Nova: Marine Worlds: 00:18:15, El Burro: 00:27:16, Heat: 00:37:35, Moon Colony Bloodbath: 00:46:319, Shackleton Base: 01:04:09, News with Tony T: 01:38:04, Theme and Mechanism Alignment: 02:31:41. Check out our sponsors Restoration Games at https://restorationgames.com/. Game Toppers at https://www.gametoppersllc.com/. And Game Night Picks at http://gamenightpicks.com/cabal.

In this episode of the Oncology Brothers podcast, Drs. Rohit & Rahul Gosain welcome Dr. Jacob Sands, a thoracic medical oncologist from the Dana-Farber Cancer Institute, to discuss the recent FDA approval of Dato-DXD (datopotamab deruxtecan) for previously treated EGFR-mutated non-small cell lung cancer (NSCLC). Key Topics: •⁠  ⁠Overview of Dato-DXd and its FDA approval •⁠  ⁠Mechanism of action and study design of the TROPION Lung trials •⁠  ⁠Efficacy and safety profile of Dato-DXd •⁠  ⁠Management of side effects and clinical pearls •⁠  ⁠Treatment sequencing for EGFR-mutated NSCLC Join us as we dive into the details of the TROPION Lung trials that led to this significant approval, the mechanism of action of Dato-DXd, and the implications for patients with various EGFR mutations.  Dr. Sands shared insights on the study design, efficacy, and tolerability of this new antibody-drug conjugate, as well as important clinical pearls for managing side effects such as stomatitis, dry eyes, and interstitial lung disease (ILD). We also explored the current treatment landscape for EGFR-mutated NSCLC, including the sequencing of therapies and the potential role of Dato-DXd in clinical practice. Tune in for an informative discussion that highlights the exciting advancements in oncology and the hope they bring to patients. Follow us on social media: •⁠  ⁠X/Twitter: https://twitter.com/oncbrothers •⁠  ⁠Instagram: https://www.instagram.com/oncbrothers •⁠  Website: https://oncbrothers.com/ Don't forget to like, subscribe, and check out our other episodes for more insights into the world of oncology!

Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/

Solifenacin is a bladder antimuscarinic medication most commonly used for overactive bladder (OAB) with symptoms of urinary frequency, urgency, and urge incontinence. Like other agents in its class, understanding the pharmacology can help anticipate potential side effects, drug interactions, and downstream prescribing problems. Mechanism of Action Solifenacin selectively blocks muscarinic M3 receptors in the bladder detrusor muscle. Inhibiting these receptors reduces involuntary bladder contractions, increases bladder capacity, and delays the urge to void. While M3 selectivity may theoretically reduce side effects compared to nonselective antimuscarinics, in clinical practice, many anticholinergic effects still occur. Adverse Effects Because muscarinic receptors are present throughout the body, solifenacin can lead to a range of anticholinergic adverse effects: Dry mouth – among the most common, can be significant enough to cause dental issues with long-term use. Constipation – especially problematic in older adults; severe cases may require hospitalization. Blurred vision – due to impaired accommodation. Cognitive impairment – increased risk in older adults, particularly with cumulative anticholinergic burden. Urinary retention – paradoxical worsening in patients with bladder outlet obstruction. Drug Interactions CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin, ritonavir) can increase solifenacin plasma concentrations, raising the risk of side effects. Other anticholinergics (e.g., diphenhydramine, tricyclic antidepressants, other bladder antimuscarinics) can result in additive toxicity and higher anticholinergic burden. QT-prolonging drugs (e.g., amiodarone, certain fluoroquinolones) may have additive cardiac risk since solifenacin has been associated with QT prolongation in rare cases. Prescribing Cascade Examples Constipation → Laxative initiation – A patient starts solifenacin for OAB and develops severe constipation, leading to chronic use of stimulant laxatives like senna or bisacodyl. Dry mouth → Mouth rinse prescription – Dry mouth is treated with saliva substitutes or prescription rinses, instead of reassessing the anticholinergic therapy. Cognitive decline → Donepezil initiation – In older adults, cognitive impairment may be mistaken for dementia progression, leading to cholinesterase inhibitor prescribing—directly counteracting the anticholinergic effects of solifenacin. Solifenacin can be an effective treatment for OAB, but the risk of adverse effects and prescribing cascades—especially in older adults—cannot be ignored. Healthcare professionals should regularly review the indication, monitor for anticholinergic burden, and look for opportunities to deprescribe when appropriate.

We Got This With Mark and Hal determines the best door opening mechanism of all time. This decision is legally binding.

PEEPanEIP - EIP-7892: Blob Parameter Only Hardforks PEEPanEIP - EIP-7892: Blob Parameter Only Hardforks In this episode, Pooja Ranjan discusses EIP 7892 with Mark Mackey, exploring its implications for Ethereum's scalability and the innovative approach to managing blob capacity. They delve into the technical aspects of the proposal, the importance of community involvement, and the future of Ethereum upgrades. Mark shares insights from his journey as a client developer and emphasizes the collaborative nature of the Ethereum community.

Watch hol+ by Dr. Taz MD on YouTube: https://www.youtube.com/@DrTazMD/podcastsAre you looking to proactively address metabolic disruptions and create a healthier lifestyle? In this episode of hol+, Dr. Taz MD explores the pressing issue of metabolic health and the economic burden of metabolic diseases, which cost around $427 billion annually. Dr. Taz addresses the common misconceptions about metabolic health, emphasizing that it encompasses more than just weight management. The episode delves into the mechanisms of GLP-1 medications, their effects, and the holistic strategies required to manage metabolic health effectively. By addressing inflammation, hormonal imbalances, and gut health, Dr. Taz provides a comprehensive guide to improving metabolic health for individuals and families alike. Connect further to Hol+ at https://holplus.co/- Don't forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Stay ConnectedSubscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsFollow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Join the conversation on X: https://x.com/@drtazmdTikTok: https://www.tiktok.com/@drtazmdFacebook: https://www.facebook.com/drtazmd/Host & Production TeamHost: Dr. Taz; Produced by Rainbow Creative (Executive Producer: Matthew Jones; Lead Producer: Lauren Feighan; Editors: Jeremiah Schultz and Patrick Edwards)05:30 The Financial Burden of Metabolic Disease08:19 Mechanism and Impact of GLP-1 Medications16:19 Diagnosing Metabolic Disease25:52 Medications: Finding the Right Balance29:17 Understanding Inflammation and Its Impact33:44 Hormones and Metabolic Health37:00 The Role of Gut Health in Metabolism39:11 Environmental Toxins and Metabolic Disease41:48 Building a Holistic Metabolic Plan44:44 Final Thoughts and Practical Steps

Melissa and Jam explore the science behind why sweat is salty. They discuss personal experiences with sweating, the types of sweat glands, and the chemical processes involved in sweat production. The episode explains how osmosis, ion channels, and salt concentrations contribute to the movement of sweat through sweat glands to the skin's surface. They also touch on evolutionary aspects and the role of sweat in cooling the body. For anyone curious about the chemistry of everyday life, this episode offers an accessible and intriguing explanation. 00:00 Introduction: Why is Sweat Salty? 00:27 Personal Experiences with Sweat 01:32 The Science Behind Sweat 02:00 Meet the Hosts 02:20 Types of Sweat Glands 04:30 How Sweat Reaches the Skin 07:31 The Role of Salt in Sweat 14:20 Health Indicators in Sweat 17:01 Understanding Osmosis and Interstitial Fluid 17:39 Evolutionary Perspective on Sweating 20:01 Mechanism of Sweat Glands 22:41 Sweat Composition and Function 27:39 Personal Sweating Experiences 33:47 Supporting the Show and Community ★ Support this podcast on Patreon ★ ★ Buy Podcast Merch and Apparel ★ Check out our website at chemforyourlife.com Watch our episodes on YouTube Find us on Instagram, Twitter, and Facebook @ChemForYourLife References from this episode: https://pmc.ncbi.nlm.nih.gov/articles/PMC6773238/ https://pubs.rsc.org/en/content/articlehtml/2024/lc/d3lc00874f#cit23 https://pubs.acs.org/doi/full/10.1021/acsnano.4c10344 Thanks to our monthly supporters Vince W Julie S. Heather R Autoclave Chelsea M Dorien VD Scott B Jessie R Ciara L J0HNTR0Y Jeannette N Cullyn R Erica B Elizabeth P Sarah M Rachel R Letila Katrina B Suzanne P Venus R Lyn S Jacob T Brian K Emerson W Kristina G Timothy P Steven B Chris and Claire S Chelsea B Avishai B Hunter R ★ Support this podcast on Patreon ★ ★ Buy Podcast Merch and Apparel ★ Check out our website at chemforyourlife.com Watch our episodes on YouTube Find us on Instagram, Twitter, and Facebook @ChemForYourLife

It's no secret that humans are conditioned to look for the negative.    The constant battle against negativity rages every single day.    Print.    TV.    Social media.    We can't get through our days without some negative news trying to penetrate our mentality.    What happens when we're faced with negativity is our brains are positioned to fight or flight.    But, what if there was a way to break out of this.    There is a way, and it takes focus, consistency, and practice.    And it's possible to do it easily.    The first thing you have to do is correct the trigger when you want to dive into the same stream of negativity the world brings you.    If someone wants to argue, find a way to diffuse it, no matter who is right or wrong.    When someone comes in and throws things into chaos, don't accept it as a problem you need to solve.    In moments of great stress,  and negativity, motivate yourself with love, gratitude, and abundance.    When you rewire your mind against its nature, you can operate from a place of love.    It's going to take some work, but when you do, watch the world you create change right in front of your face.    Most of the things we worry about never come to fruition.    Follow the path of inpenetrable positivity and let life flow.    About the ReWire Podcast   The ReWire Podcast with Ryan Stewman – Dive into powerful insights as Ryan Stewman, the HardCore Closer, breaks down mental barriers and shares actionable steps to rewire your thoughts. Each episode is a fast-paced journey designed to reshape your mindset, align your actions, and guide you toward becoming the best version of yourself. Join in for a daily dose of real talk that empowers you to embrace change and unlock your full potential.    Learn how you can become a member of a powerful community consistently rewiring itself for success at https://www.jointheapex.com/   Rise Above

Recorded with a live audience in Cambridge, this captivating conversation delves deep into the life and career of a cultural force of the last half-century. Known of course for his iconic role as Baldrick in Blackadder, Sir Tony's sharp intelligence and dry humour have had a formative influence on generations.  In this candid discussion, he opens up about the unexpected turns and profound challenges that have shaped his extraordinary journey as an actor, presenter, documentary maker and writer. You'll hear his deeply personal reflections on fatherhood, insights into the creative process behind his recently announced novel, and the powerful lessons learned from a lifetime of experiences, both public and private.  Prepare for an engaging, wise, and moving conversation that explores the transformative power of vulnerability and the importance of finding meaningful connection. This is a unique opportunity to hear a national treasure like never before. ✨ IN THIS EPISODE: 00:00 Intro 00:45 Tony Robinson's Early Life and Career 03:13 Fatherhood and Family 04:55 Writing and Publishing a Novel 10:50 The Impact of Blackadder 13:16 Challenges and Conflicts in Blackadder 16:33 Height and Personal Insecurities 20:42 Childhood and Adolescence Struggles 22:41 Growing Up in the Shadow of WWII 24:49 The Ups and Downs of Gambling 27:28 Early Career and Poker Lessons 29:29 Child Actor Earnings and Capitalism 34:23 Dealing with Alzheimer's in the Family 37:03 Reflecting on Personal Failures 44:56 Finding Meaningful Relationships

Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/

Join us as we dive deep into pectoralis major tears. We'll discuss the anatomy of the pectoralis major, typical mechanisms of injury, and examination methods to diagnose these tears accurately. We also cover risk factors, differential diagnosis, and imaging options. Finally, we'll talk about treatment plans, both conservative and surgical, and the importance of understanding tissue healing timelines. 00:00 Introduction to the Podcast and Today's Topic01:18 Anatomy of the Pectoral Major02:10 Mechanism of Injury and Common Symptoms03:53 Assessment and Diagnosis06:38 Imaging and Differential Diagnosis07:31 Treatment Options: Conservative vs. Surgical08:44 Post-Surgical Rehabilitation Phases11:00 Key Takeaways and ConclusionSupport the showWhy PT Snacks Podcast?This podcast is your go-to for bite-sized, practical info designed for busy, overwhelmed Physical Therapists and students who want to build confidence in their foundational knowledge without sacrificing life's other priorities. Stay Connected! Never miss an episode—hit follow now! Got questions? Email me at ptsnackspodcast@gmail.com or leave feedback HERE. Join the email list HERE On Instagram? Find unique content at @dr.kasey.hankins! Need CEUs Fast?Time and resources short? Medbridge has you covered: Get over $100 off a subscription with code PTSNACKSPODCAST: Medbridge Students: Save $75 off a student subscription with code PTSNACKSPODCASTSTUDENT—a full year of unlimited access for less!(These are affiliate links, but I only recommend Medbridge because it's genuinely valuable.) Optimize Your Patient Care with Tindeq: Get 10% off with code PTSNACKS10: [Tindeq] ...

About Bernardo:Bern Mendez is a neuroscience-based dating and relationship coach with 14 years of experience helping successful women thriving in midlife—but not yet in love—move past hidden emotional barriers into clear, committed relationships.His practical method blends neuroscience, trauma-informed somatic work, polyvagal theory, and attachment research, helping women regulate their nervous systems, clarify what they genuinely want, and choose partners who can truly meet them there.Bern's YouTube channel has drawn over 30 million views and 227,000 subscribers, making it one of the top 12 dating advice channels for women worldwide. Featured by CNN, HuffPost, Redbook, Univision, and MindBodyGreen, Bern coaches women globally from his home base in Austin, Texas.Summary:In this episode of the Better Divorce Podcast, host Paulette Rigo and guest Bern Mendez explore the complexities of dating and relationships post-divorce. They discuss how personal experiences shape our understanding of love and attraction, the role of the nervous system in partner selection, and the importance of self-awareness and emotional health in creating sustainable relationships. Bern shares his journey from personal pain to helping others navigate their relationship challenges, emphasizing the need for intentionality in dating and the significance of understanding attachment styles. The conversation highlights practical strategies for rewiring attraction patterns and recognizing unhealthy relationship dynamics, ultimately encouraging listeners to seek help and embrace personal growth. In this conversation, Bern Mendez and Paulette Rigo explore the complexities of modern dating, emphasizing the psychological and emotional aspects of connection. They discuss the addictive nature of dating apps, the importance of authenticity, and the pressures women face in the dating landscape. The dialogue also touches on the hero's journey in relationships, the balance between passion and stability, and the significance of flirting and human connection. Ultimately, they encourage listeners to take their time in finding love and to set healthy boundaries in their dating lives.Takeaways:The nervous system plays a crucial role in partner selection.Personal experiences, including loss, can drive one's purpose.Understanding attachment styles is vital for relationship success.Rewiring attraction patterns requires intentional effort.Breathing techniques can help regulate emotional responses.Recognizing unhealthy relationship dynamics is essential for healing.Seeking help is a sign of strength, not weakness.Relationships require ongoing learning and adaptation.Self-awareness is key to navigating post-divorce dating.Daily practices can facilitate personal growth and emotional health. The cycle of connection and addiction is real and affects dating.Modern dating can feel overwhelming due to societal pressures.Authenticity is crucial in finding the right partner.It's important to ask powerful questions early in dating.Healthy love should feel like a safe home, not chaos.Flirting is a lost art that needs to be revived.Dating can be a spiritual journey of self-discovery.Setting boundaries is essential for healthy relationships.Take the time to find the right person for you.You can absolutely get what you want in love if you learn the necessary skills.

Rachelle Robinett, founder of Pharmakon Supernatural and educator in holistic health, offers a clear, science-aware framework for supporting energy, focus, and stress regulation, without defaulting to pharmaceuticals or overstimulation. In this episode, she explores how plant-based medicine, nutrition, and daily practices can be woven into practical, long-term routines that support resilience and cognitive clarity.   Robinett challenges the assumption that performance must rely on synthetic energy or end in burnout. Drawing from her work at the intersection of herbalism and evidence-based wellness, she shares actionable strategies for optimizing physiological readiness through balance, not intensity.   “I'm really interested in how we can live well without needing to biohack or rely on pharmaceuticals or stimulants or even supplementation all the time.”   Key insights from the conversation include: Stimulants Borrow, Not Create Energy Robinett explains that caffeine and similar compounds don't give us energy; they “just turn off the signals of fatigue.” Instead, she emphasizes rhythm management, aligning with circadian patterns and energy cycles: “You don't have to be on all the time. And if we try to be, the crash will always come.”   Herbs Should Be Matched to Mechanism, Not Trend She encourages listeners to move beyond marketing labels like “adaptogen,” noting that compounds like rhodiola (stimulating) and reishi (sedating) serve very different roles.  “Match your plants to your goals... It's kind of like caffeine; if you don't need it, don't take it.”   Sugar Is Energizing, But Often Disruptive Robinett discusses how sugar can be paired with fiber, fat, or protein to reduce its volatility: “Sugar is biologically energizing… but we tend to use it in ways that give us a spike and then a crash.”   Daily Practices Outperform Sporadic Interventions Light exposure, meal timing, and breathwork help regulate the autonomic nervous system more effectively than isolated hacks: “What we do daily matters more than what we do occasionally… so many people don't understand how profoundly their breathing patterns are affecting their state.”   Recovery Is an Active Recalibration Robinett distinguishes between activities that feel restful and those that actually reset the stress response system: “Sometimes the things we think are relaxing are not—Netflix, alcohol, even yoga. True recovery is shifting the nervous system.”   This conversation reframes wellness not as indulgence or optimization, but as physiological literacy—a disciplined, systems-level approach to mental clarity and endurance. For professionals seeking alternatives to overstimulation, Robinett offers a sustainable path toward long-term resilience and regulated energy.   Get Rachelle's book here: https://shorturl.at/q7TDb Naturally: The Herbalist's Guide to Health and Transformation   Here are some free gifts for you: Overall Approach Used in Well-Managed Strategy Studies free download: www.firmsconsulting.com/OverallApproach   McKinsey & BCG winning resume free download: www.firmsconsulting.com/resumepdf   Enjoying this episode? Get access to sample advanced training episodes here: www.firmsconsulting.com/promo

Have you ever wondered what happens when a toddler gets into something they definitely shouldn't? Today, Dr. Monica Gray, Dr. Pradip Kamat, and Dr. Rahul Damania discuss the case of an 18-month-old boy who accidentally ingested concentrated bleach, presenting with stridor, drooling, and vomiting. They review the clinical approach to caustic ingestions in children, including airway management, diagnostic workup, and the roles of endoscopy, steroids, and multidisciplinary care. The episode also highlights potential complications such as esophageal strictures and cancer, emphasizes prevention strategies, and provides key takeaways for intensivists managing similar pediatric emergencies. If you're an intensivist or just want to know what to do in a pediatric emergency, don't miss these essential takeaways for managing one of the scariest situations in the ER.Show Highlights:Case study of an 18-month-old boy who ingested concentrated bleachClinical presentation including symptoms like stridor, drooling, and vomitingManagement strategies for caustic ingestions in childrenImportance of airway management and monitoring in cases of caustic ingestionDiagnostic workup including imaging and endoscopyDifferential diagnosis considerations for similar presentations (e.g., button batteries, laundry detergent pods)Mechanism of injury caused by alkaline substances like bleachLong-term complications associated with caustic ingestions, such as esophageal strictures and cancerMultidisciplinary approach to treatment involving various medical specialtiesPrevention strategies to reduce the incidence of accidental caustic ingestions in childrenReferences:American Academy of Pediatrics – Pediatric Care Online: Esophageal Caustic Injury (AAP clinical guidance on caustic ingestions).Fuhrman & Zimmerman's Pediatric Critical Care textbook – Chapters on toxicology and gastrointestinal emergencies (covering caustic injury management and critical care approach).Hoffman RS, et al. “Ingestion of Caustic Substances.” New England Journal of Medicine. 2020; 382(18):1739-1748. A comprehensive review of caustic ingestion injuries and management.Arnold M, Numanoglu A. “Caustic ingestion in children – a review.” Semin Pediatr Surg. 2017;26(2):95-104. Review of epidemiology, pathophysiology, and treatment of caustic injuries in kids.Johnson CM, Brigger MT. “The public health impact of pediatric caustic ingestion injuries.” Arch Otolaryngol Head Neck Surg. 2012;138(12):1111-1115. (Epidemiology study showing declining incidence).Pediatric Critical Care Medicine (PCCM) Journal – various case reports and series on caustic ingestion (for case-based insights), and annual National Poison Data System reports (for statistics on pediatric poisonings).Tringali A, et al. ESGE/ESPGHAN Pediatric GI Endoscopy Guidelines (Endoscopy, 2017) – Includes recommendations for endoscopy timing and steroid use in caustic ingestions.Usta M, et al. “High doses of methylprednisolone in the management of caustic esophageal burns.” Pediatrics. 2014;133(6):E1518-24. (Key study demonstrating steroids benefit in grade 2b injuries).Royal Children's Hospital Melbourne – Clinical Practice Guidelines: Caustic Ingestions (2019) – Practical hospital guidelines emphasizing early intubation for airway threat, endoscopy within 24h, IV PPI, and supportive care.

Steven Rabalais, litigator and author of General Fox Conner: Pershing's Chief of Operations and Eisenhower's Mentor,  joins the show to discuss the extraordinary influence of now-forgotten General Fox Connor on the outcome of WWI and Eisenhower's career.   ▪️ Times     •      01:51 Introduction     •      03:10 Growing up with history      •      05:47 A southern story      •      07:44 West Point struggles      •      12:07 A reader            •      14:50 Coastal artillery          •      20:46 Rocks and airplanes     •      23:51 Mechanism of victory     •      27:54 WWI logistics        •      32:47 Summer 1918     •      46:03 Eisenhower     •      51:24 Panama        •      01:01:58 Foreshadowing Follow along on Instagram, X @schoolofwarpod, and YouTube @SchoolofWarPodcast Find a transcript of today's episode on our School of War Substack

In this week's episode, we'll learn about a JAK inhibitor to prevent complications of CD19-directed CAR T-cell therapy. In a phase 2 study, itacitinib was well tolerated and demonstrated promising reductions in the incidence of cytokine release syndrome and neurotoxicity. After that: investigators report direct interactions between ChAdOx1 and platelets under arterial shear conditions. Investigators say it's a novel biophysical mechanism that potentially contributes to post-vaccination arterial thrombosis. Finally, we explore lineage switch, an emerging form of acute leukemia relapse with dismal outcomes. It arises rapidly following antigen-targeted immunotherapy, highlighting the importance of advanced methods for detection and treatment.Featured Articles: Itacitinib for the prevention of IEC therapy–associated CRS: results from the 2-part phase 2 INCB 39110-211 studyShear-dependent platelet aggregation by ChAdOx1 nCoV-19 vaccine: a novel biophysical mechanism for arterial thrombosisProject EVOLVE: an international analysis of postimmunotherapy lineage switch, an emergent form of relapse in leukemia

PodChatLive 189: The windlass mechanism on the moon, hip strength & ankle instability, and the impact of mental state on surgery outcomesContact us: getinvolved@podchatlive.comLinks from this week:Hip muscle strength in patients with chronic ankle instability: A systematic review and meta-analysisThe impact of mental and psychological state on metatarsophalangeal joint replacement outcomes in patients with freiberg's infractionAn Examination of Foot Dynamics under Terrestrial andLunar Gravity

Sid Mangalik and Andrew Clark explore the unique governance challenges of agentic AI systems, highlighting the compounding error rates, security risks, and hidden costs that organizations must address when implementing multi-step AI processes. Show notes:• Agentic AI systems require governance at every step: perception, reasoning, action, and learning• Error rates compound dramatically in multi-step processes - a 90% accurate model per step becomes only 65% accurate over four steps• Two-way information flow creates new security and confidentiality vulnerabilities. For example, targeted prompting to improve awareness comes at the cost of performance. (arXiv, May 24, 2025)• Traditional governance approaches are insufficient for the complexity of agentic systems• Organizations must implement granular monitoring, logging, and validation for each component• Human-in-the-loop oversight is not a substitute for robust governance frameworks• The true cost of agentic systems includes governance overhead, monitoring tools, and human expertiseMake sure you check out Part 1: Mechanism design, Part 2: Utility functions, and Part 3: Linear programming. If you're building agentic AI systems, we'd love to hear your questions and experiences. Contact us.What we're reading:We took reading "break" this episode to celebrate Sid! This month, he successfully defended his Ph.D. Thesis on "Psychological Health and Belief Measurement at Scale Through Language." Say congrats!>>What did you think? Let us know.Do you have a question or a discussion topic for the AI Fundamentalists? Connect with them to comment on your favorite topics: LinkedIn - Episode summaries, shares of cited articles, and more. YouTube - Was it something that we said? Good. Share your favorite quotes. Visit our page - see past episodes and submit your feedback! It continues to inspire future episodes.

In the first episode of our Rare Lung Diseases podcast series, host Saranya Ravindran speaks with James Stoller, Chief of Education and Pulmonary Physician at Cleveland Clinic, about Alpha-1 antitrypsin deficiency, a rare genetic condition that is frequently underdiagnosed. The discussion explores the complexities of Alpha 1, including current challenges in detection, advances in diagnosis and management, and what the future may hold for improving care. Timestamps 00:56 – What is Alpha-1 antitrypsin deficiency? 01:45 – Mechanism of this genetic disorder 03:12 – What makes Alpha 1 so hard to spot? 04:30 – Genetic complexities of Alpha 1 06:00 – Risk factors  

Writing Embodiment in Victorian Microscopy: Beautiful Mechanism (Oxford UP, 2025) by Dr. Meegan Kennedy examines a revolutionary period in microscopical technology and practice. At first considered a mere toy, by 1900 the microscope rivaled the railway and telegraph as an emblem of modernity and enjoyed an astonishing diversity of applications. This technology could drive scientific debates on subjects like cell theory, vitalism, and bacteriology; guide workers in classrooms, laboratories, and businesses; and inspire a personal hobby or a mass entertainment. Victorian microscopy productively cuts across the ostensibly separate domains of science, religion, commerce, art, education, entertainment, and domestic life.Writing Embodiment in Victorian Microscopy reads nineteenth-century microscopy across scientific, literary, religious, and popular texts. It argues that Victorian microscopists saw their vision and cognition as fully embodied experiences, the images emerging through a material entanglement of bodies (observer, instrument, apparatus, object) in a dynamic, unstable system. These ideas echo the work of physiological psychologists, who proposed mind as a system of embodied, distributed, and dynamic processes shaped by automatic or unconscious reflex action, attention, mental training, and fatigue. Striving to regulate this complex system, microscopists circulated tropes of embodiment through the varied forms of nineteenth-century print culture. They adapted existing concepts (such as beauty, the sublime, natural theology, and fairylands), or coined new phrases (such as many-sided comprehension), to promote favored forms of embodiment and enculturate microscopy as a difficult but valuable pursuit. Writing Embodiment draws on important work in book history and periodical studies by emphasizing the circulation of these tropes in intermedial conversations across diverse print forms.Victorians understood wonder and skepticism not as incommensurate approaches to scientific observation but rather as complementary forms of embodiment. Romantic tropes of wonder solicit affective flows from observer to wriggling animalcule and back; while skeptical, realist tropes offer to train the reader's eye, hand, body, and judgment and to formalize microscopical practice. Microscopical narratives may manipulate wonder and skepticism in productive tension or create virtual storyspaces that enlist the reader in virtual witnessing. These tropes shape every level of microscopical interest and proficiency. By analyzing their use and circulation, Writing Embodiment illuminates wider patterns of Victorian thought on embodiment, scientific practice, and community. This interview was conducted by Dr. Miranda Melcher whose book focuses on post-conflict military integration, understanding treaty negotiation and implementation in civil war contexts, with qualitative analysis of the Angolan and Mozambican civil wars. You can find Miranda's interviews on New Books with Miranda Melcher, wherever you get your podcasts. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

Writing Embodiment in Victorian Microscopy: Beautiful Mechanism (Oxford UP, 2025) by Dr. Meegan Kennedy examines a revolutionary period in microscopical technology and practice. At first considered a mere toy, by 1900 the microscope rivaled the railway and telegraph as an emblem of modernity and enjoyed an astonishing diversity of applications. This technology could drive scientific debates on subjects like cell theory, vitalism, and bacteriology; guide workers in classrooms, laboratories, and businesses; and inspire a personal hobby or a mass entertainment. Victorian microscopy productively cuts across the ostensibly separate domains of science, religion, commerce, art, education, entertainment, and domestic life.Writing Embodiment in Victorian Microscopy reads nineteenth-century microscopy across scientific, literary, religious, and popular texts. It argues that Victorian microscopists saw their vision and cognition as fully embodied experiences, the images emerging through a material entanglement of bodies (observer, instrument, apparatus, object) in a dynamic, unstable system. These ideas echo the work of physiological psychologists, who proposed mind as a system of embodied, distributed, and dynamic processes shaped by automatic or unconscious reflex action, attention, mental training, and fatigue. Striving to regulate this complex system, microscopists circulated tropes of embodiment through the varied forms of nineteenth-century print culture. They adapted existing concepts (such as beauty, the sublime, natural theology, and fairylands), or coined new phrases (such as many-sided comprehension), to promote favored forms of embodiment and enculturate microscopy as a difficult but valuable pursuit. Writing Embodiment draws on important work in book history and periodical studies by emphasizing the circulation of these tropes in intermedial conversations across diverse print forms.Victorians understood wonder and skepticism not as incommensurate approaches to scientific observation but rather as complementary forms of embodiment. Romantic tropes of wonder solicit affective flows from observer to wriggling animalcule and back; while skeptical, realist tropes offer to train the reader's eye, hand, body, and judgment and to formalize microscopical practice. Microscopical narratives may manipulate wonder and skepticism in productive tension or create virtual storyspaces that enlist the reader in virtual witnessing. These tropes shape every level of microscopical interest and proficiency. By analyzing their use and circulation, Writing Embodiment illuminates wider patterns of Victorian thought on embodiment, scientific practice, and community. This interview was conducted by Dr. Miranda Melcher whose book focuses on post-conflict military integration, understanding treaty negotiation and implementation in civil war contexts, with qualitative analysis of the Angolan and Mozambican civil wars. You can find Miranda's interviews on New Books with Miranda Melcher, wherever you get your podcasts. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/history

Writing Embodiment in Victorian Microscopy: Beautiful Mechanism (Oxford UP, 2025) by Dr. Meegan Kennedy examines a revolutionary period in microscopical technology and practice. At first considered a mere toy, by 1900 the microscope rivaled the railway and telegraph as an emblem of modernity and enjoyed an astonishing diversity of applications. This technology could drive scientific debates on subjects like cell theory, vitalism, and bacteriology; guide workers in classrooms, laboratories, and businesses; and inspire a personal hobby or a mass entertainment. Victorian microscopy productively cuts across the ostensibly separate domains of science, religion, commerce, art, education, entertainment, and domestic life.Writing Embodiment in Victorian Microscopy reads nineteenth-century microscopy across scientific, literary, religious, and popular texts. It argues that Victorian microscopists saw their vision and cognition as fully embodied experiences, the images emerging through a material entanglement of bodies (observer, instrument, apparatus, object) in a dynamic, unstable system. These ideas echo the work of physiological psychologists, who proposed mind as a system of embodied, distributed, and dynamic processes shaped by automatic or unconscious reflex action, attention, mental training, and fatigue. Striving to regulate this complex system, microscopists circulated tropes of embodiment through the varied forms of nineteenth-century print culture. They adapted existing concepts (such as beauty, the sublime, natural theology, and fairylands), or coined new phrases (such as many-sided comprehension), to promote favored forms of embodiment and enculturate microscopy as a difficult but valuable pursuit. Writing Embodiment draws on important work in book history and periodical studies by emphasizing the circulation of these tropes in intermedial conversations across diverse print forms.Victorians understood wonder and skepticism not as incommensurate approaches to scientific observation but rather as complementary forms of embodiment. Romantic tropes of wonder solicit affective flows from observer to wriggling animalcule and back; while skeptical, realist tropes offer to train the reader's eye, hand, body, and judgment and to formalize microscopical practice. Microscopical narratives may manipulate wonder and skepticism in productive tension or create virtual storyspaces that enlist the reader in virtual witnessing. These tropes shape every level of microscopical interest and proficiency. By analyzing their use and circulation, Writing Embodiment illuminates wider patterns of Victorian thought on embodiment, scientific practice, and community. This interview was conducted by Dr. Miranda Melcher whose book focuses on post-conflict military integration, understanding treaty negotiation and implementation in civil war contexts, with qualitative analysis of the Angolan and Mozambican civil wars. You can find Miranda's interviews on New Books with Miranda Melcher, wherever you get your podcasts. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/european-studies

Writing Embodiment in Victorian Microscopy: Beautiful Mechanism (Oxford UP, 2025) by Dr. Meegan Kennedy examines a revolutionary period in microscopical technology and practice. At first considered a mere toy, by 1900 the microscope rivaled the railway and telegraph as an emblem of modernity and enjoyed an astonishing diversity of applications. This technology could drive scientific debates on subjects like cell theory, vitalism, and bacteriology; guide workers in classrooms, laboratories, and businesses; and inspire a personal hobby or a mass entertainment. Victorian microscopy productively cuts across the ostensibly separate domains of science, religion, commerce, art, education, entertainment, and domestic life.Writing Embodiment in Victorian Microscopy reads nineteenth-century microscopy across scientific, literary, religious, and popular texts. It argues that Victorian microscopists saw their vision and cognition as fully embodied experiences, the images emerging through a material entanglement of bodies (observer, instrument, apparatus, object) in a dynamic, unstable system. These ideas echo the work of physiological psychologists, who proposed mind as a system of embodied, distributed, and dynamic processes shaped by automatic or unconscious reflex action, attention, mental training, and fatigue. Striving to regulate this complex system, microscopists circulated tropes of embodiment through the varied forms of nineteenth-century print culture. They adapted existing concepts (such as beauty, the sublime, natural theology, and fairylands), or coined new phrases (such as many-sided comprehension), to promote favored forms of embodiment and enculturate microscopy as a difficult but valuable pursuit. Writing Embodiment draws on important work in book history and periodical studies by emphasizing the circulation of these tropes in intermedial conversations across diverse print forms.Victorians understood wonder and skepticism not as incommensurate approaches to scientific observation but rather as complementary forms of embodiment. Romantic tropes of wonder solicit affective flows from observer to wriggling animalcule and back; while skeptical, realist tropes offer to train the reader's eye, hand, body, and judgment and to formalize microscopical practice. Microscopical narratives may manipulate wonder and skepticism in productive tension or create virtual storyspaces that enlist the reader in virtual witnessing. These tropes shape every level of microscopical interest and proficiency. By analyzing their use and circulation, Writing Embodiment illuminates wider patterns of Victorian thought on embodiment, scientific practice, and community. This interview was conducted by Dr. Miranda Melcher whose book focuses on post-conflict military integration, understanding treaty negotiation and implementation in civil war contexts, with qualitative analysis of the Angolan and Mozambican civil wars. You can find Miranda's interviews on New Books with Miranda Melcher, wherever you get your podcasts. Learn more about your ad choices. Visit megaphone.fm/adchoices

Writing Embodiment in Victorian Microscopy: Beautiful Mechanism (Oxford UP, 2025) by Dr. Meegan Kennedy examines a revolutionary period in microscopical technology and practice. At first considered a mere toy, by 1900 the microscope rivaled the railway and telegraph as an emblem of modernity and enjoyed an astonishing diversity of applications. This technology could drive scientific debates on subjects like cell theory, vitalism, and bacteriology; guide workers in classrooms, laboratories, and businesses; and inspire a personal hobby or a mass entertainment. Victorian microscopy productively cuts across the ostensibly separate domains of science, religion, commerce, art, education, entertainment, and domestic life.Writing Embodiment in Victorian Microscopy reads nineteenth-century microscopy across scientific, literary, religious, and popular texts. It argues that Victorian microscopists saw their vision and cognition as fully embodied experiences, the images emerging through a material entanglement of bodies (observer, instrument, apparatus, object) in a dynamic, unstable system. These ideas echo the work of physiological psychologists, who proposed mind as a system of embodied, distributed, and dynamic processes shaped by automatic or unconscious reflex action, attention, mental training, and fatigue. Striving to regulate this complex system, microscopists circulated tropes of embodiment through the varied forms of nineteenth-century print culture. They adapted existing concepts (such as beauty, the sublime, natural theology, and fairylands), or coined new phrases (such as many-sided comprehension), to promote favored forms of embodiment and enculturate microscopy as a difficult but valuable pursuit. Writing Embodiment draws on important work in book history and periodical studies by emphasizing the circulation of these tropes in intermedial conversations across diverse print forms.Victorians understood wonder and skepticism not as incommensurate approaches to scientific observation but rather as complementary forms of embodiment. Romantic tropes of wonder solicit affective flows from observer to wriggling animalcule and back; while skeptical, realist tropes offer to train the reader's eye, hand, body, and judgment and to formalize microscopical practice. Microscopical narratives may manipulate wonder and skepticism in productive tension or create virtual storyspaces that enlist the reader in virtual witnessing. These tropes shape every level of microscopical interest and proficiency. By analyzing their use and circulation, Writing Embodiment illuminates wider patterns of Victorian thought on embodiment, scientific practice, and community. This interview was conducted by Dr. Miranda Melcher whose book focuses on post-conflict military integration, understanding treaty negotiation and implementation in civil war contexts, with qualitative analysis of the Angolan and Mozambican civil wars. You can find Miranda's interviews on New Books with Miranda Melcher, wherever you get your podcasts. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science-technology-and-society

Writing Embodiment in Victorian Microscopy: Beautiful Mechanism (Oxford UP, 2025) by Dr. Meegan Kennedy examines a revolutionary period in microscopical technology and practice. At first considered a mere toy, by 1900 the microscope rivaled the railway and telegraph as an emblem of modernity and enjoyed an astonishing diversity of applications. This technology could drive scientific debates on subjects like cell theory, vitalism, and bacteriology; guide workers in classrooms, laboratories, and businesses; and inspire a personal hobby or a mass entertainment. Victorian microscopy productively cuts across the ostensibly separate domains of science, religion, commerce, art, education, entertainment, and domestic life.Writing Embodiment in Victorian Microscopy reads nineteenth-century microscopy across scientific, literary, religious, and popular texts. It argues that Victorian microscopists saw their vision and cognition as fully embodied experiences, the images emerging through a material entanglement of bodies (observer, instrument, apparatus, object) in a dynamic, unstable system. These ideas echo the work of physiological psychologists, who proposed mind as a system of embodied, distributed, and dynamic processes shaped by automatic or unconscious reflex action, attention, mental training, and fatigue. Striving to regulate this complex system, microscopists circulated tropes of embodiment through the varied forms of nineteenth-century print culture. They adapted existing concepts (such as beauty, the sublime, natural theology, and fairylands), or coined new phrases (such as many-sided comprehension), to promote favored forms of embodiment and enculturate microscopy as a difficult but valuable pursuit. Writing Embodiment draws on important work in book history and periodical studies by emphasizing the circulation of these tropes in intermedial conversations across diverse print forms.Victorians understood wonder and skepticism not as incommensurate approaches to scientific observation but rather as complementary forms of embodiment. Romantic tropes of wonder solicit affective flows from observer to wriggling animalcule and back; while skeptical, realist tropes offer to train the reader's eye, hand, body, and judgment and to formalize microscopical practice. Microscopical narratives may manipulate wonder and skepticism in productive tension or create virtual storyspaces that enlist the reader in virtual witnessing. These tropes shape every level of microscopical interest and proficiency. By analyzing their use and circulation, Writing Embodiment illuminates wider patterns of Victorian thought on embodiment, scientific practice, and community. This interview was conducted by Dr. Miranda Melcher whose book focuses on post-conflict military integration, understanding treaty negotiation and implementation in civil war contexts, with qualitative analysis of the Angolan and Mozambican civil wars. You can find Miranda's interviews on New Books with Miranda Melcher, wherever you get your podcasts. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/technology

Writing Embodiment in Victorian Microscopy: Beautiful Mechanism (Oxford UP, 2025) by Dr. Meegan Kennedy examines a revolutionary period in microscopical technology and practice. At first considered a mere toy, by 1900 the microscope rivaled the railway and telegraph as an emblem of modernity and enjoyed an astonishing diversity of applications. This technology could drive scientific debates on subjects like cell theory, vitalism, and bacteriology; guide workers in classrooms, laboratories, and businesses; and inspire a personal hobby or a mass entertainment. Victorian microscopy productively cuts across the ostensibly separate domains of science, religion, commerce, art, education, entertainment, and domestic life.Writing Embodiment in Victorian Microscopy reads nineteenth-century microscopy across scientific, literary, religious, and popular texts. It argues that Victorian microscopists saw their vision and cognition as fully embodied experiences, the images emerging through a material entanglement of bodies (observer, instrument, apparatus, object) in a dynamic, unstable system. These ideas echo the work of physiological psychologists, who proposed mind as a system of embodied, distributed, and dynamic processes shaped by automatic or unconscious reflex action, attention, mental training, and fatigue. Striving to regulate this complex system, microscopists circulated tropes of embodiment through the varied forms of nineteenth-century print culture. They adapted existing concepts (such as beauty, the sublime, natural theology, and fairylands), or coined new phrases (such as many-sided comprehension), to promote favored forms of embodiment and enculturate microscopy as a difficult but valuable pursuit. Writing Embodiment draws on important work in book history and periodical studies by emphasizing the circulation of these tropes in intermedial conversations across diverse print forms.Victorians understood wonder and skepticism not as incommensurate approaches to scientific observation but rather as complementary forms of embodiment. Romantic tropes of wonder solicit affective flows from observer to wriggling animalcule and back; while skeptical, realist tropes offer to train the reader's eye, hand, body, and judgment and to formalize microscopical practice. Microscopical narratives may manipulate wonder and skepticism in productive tension or create virtual storyspaces that enlist the reader in virtual witnessing. These tropes shape every level of microscopical interest and proficiency. By analyzing their use and circulation, Writing Embodiment illuminates wider patterns of Victorian thought on embodiment, scientific practice, and community. This interview was conducted by Dr. Miranda Melcher whose book focuses on post-conflict military integration, understanding treaty negotiation and implementation in civil war contexts, with qualitative analysis of the Angolan and Mozambican civil wars. You can find Miranda's interviews on New Books with Miranda Melcher, wherever you get your podcasts. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/british-studies

Sarah Kennedy of Calocurb discusses the natural and medical ways to suppress appetite, focusing on the revolutionary GLP-1 agonists (like Ozempic and Wegovy). This is truly a deep dive into the mechanism of GLP-1 and its role in regulating appetite and blood sugar. You will learn all about the innovative Calocurb supplement, founded by Sarah, which uses a patented hops extract to effectively increase GLP-1 and reduce calorie intake by 18%. A must-watch for women in midlife looking to manage their weight naturally.Go to https://calocurb.com/drstephanie to get 10% off your first purchaseEpisode overview (timestamps are approximate):(0:00) Intro/Teaser(7:00) Understanding GLP-1 and Appetite Suppression(24:00) Exploring the Effects of CaloCurb(39:00) Mechanism and Benefits of CaloCurb(43:00) Practical Strategies for Managing Hunger and Stress Eating(54:00) Research and the Future of Natural Appetite Suppression(1:03:00) BONUS: Dr. Stephanie's "After Party"Resources mentioned in this episode can be found at https://drstephanieestima.com/podcasts/ep425A huge thanks to our sponsors:BEAM MINERALS - Replenish essential minerals your body needs. Visit https://beamminerals.com/better for 20% off of the entire store. The discount is auto-applied at checkout.LVLUP  - Midlife hormonal changes can wreak havoc on your gut health. Ultimate GI Repair combines powerful gut-healing peptides with gut-nourishing naturals to soothe your changing digestion. Learn more at https://lvluphealth.com/DRSTEPHANIE and use code DRSTEPHANIE for 15% off.TIMELINE - As perimenopausal women, we know we are in a fight against time to preserve our muscle strength and endurance, plus our recovery needs are greater. That's why you save 20% at https://timelinenutrition.com/better with code BETTER.MAUI NUI VENISON - Packed with essential vitamins, minerals, and bioavailable compounds that support energy, performance, and overall health. Head over to  https://mauinuivenison.com/better to checkout their premium snack sticks and fresh starter boxes.

Have you ever wondered what happens when a toddler gets into something they definitely shouldn't? Today, Dr. Monica Gray, Dr. Pradip Kamat, and Dr. Rahul Damania discuss the case of an 18-month-old boy who accidentally ingested concentrated bleach, presenting with stridor, drooling, and vomiting. They review the clinical approach to caustic ingestions in children, including airway management, diagnostic workup, and the roles of endoscopy, steroids, and multidisciplinary care. The episode also highlights potential complications such as esophageal strictures and cancer, emphasizes prevention strategies, and provides key takeaways for intensivists managing similar pediatric emergencies. If you're an intensivist or just want to know what to do in a pediatric emergency, don't miss these essential takeaways for managing one of the scariest situations in the ER.Show Highlights:Case study of an 18-month-old boy who ingested concentrated bleachClinical presentation including symptoms like stridor, drooling, and vomitingManagement strategies for caustic ingestions in childrenImportance of airway management and monitoring in cases of caustic ingestionDiagnostic workup including imaging and endoscopyDifferential diagnosis considerations for similar presentations (e.g., button batteries, laundry detergent pods)Mechanism of injury caused by alkaline substances like bleachLong-term complications associated with caustic ingestions, such as esophageal strictures and cancerMultidisciplinary approach to treatment involving various medical specialtiesPrevention strategies to reduce the incidence of accidental caustic ingestions in childrenReferences:American Academy of Pediatrics – Pediatric Care Online: Esophageal Caustic Injury (AAP clinical guidance on caustic ingestions).Fuhrman & Zimmerman's Pediatric Critical Care textbook – Chapters on toxicology and gastrointestinal emergencies (covering caustic injury management and critical care approach).Hoffman RS, et al. “Ingestion of Caustic Substances.” New England Journal of Medicine. 2020; 382(18):1739-1748. A comprehensive review of caustic ingestion injuries and management.Arnold M, Numanoglu A. “Caustic ingestion in children – a review.” Semin Pediatr Surg. 2017;26(2):95-104. Review of epidemiology, pathophysiology, and treatment of caustic injuries in kids.Johnson CM, Brigger MT. “The public health impact of pediatric caustic ingestion injuries.” Arch Otolaryngol Head Neck Surg. 2012;138(12):1111-1115. (Epidemiology study showing declining incidence).Pediatric Critical Care Medicine (PCCM) Journal – various case reports and series on caustic ingestion (for case-based insights), and annual National Poison Data System reports (for statistics on pediatric poisonings).Tringali A, et al. ESGE/ESPGHAN Pediatric GI Endoscopy Guidelines (Endoscopy, 2017) – Includes recommendations for endoscopy timing and steroid use in caustic ingestions.Usta M, et al. “High doses of methylprednisolone in the management of caustic esophageal burns.” Pediatrics. 2014;133(6):E1518-24. (Key study demonstrating steroids benefit in grade 2b injuries).Royal Children's Hospital Melbourne – Clinical Practice Guidelines: Caustic Ingestions (2019) – Practical hospital guidelines emphasizing early intubation for airway threat, endoscopy within 24h, IV PPI, and supportive care.

On University at Albany Week: Understanding what drives antimicrobial resistance is crucial. Cheryl Andam, associate professor in the department of biological sciences at the RNA Institute, identifies a new mechanism. Cheryl Andam is an associate professor in UAlbany's Department of Biological Sciences. She works on the genome evolution of bacterial pathogens, with a focus on antimicrobial […]

We continue with our series about building agentic AI systems from the ground up and for desired accuracy.  In this episode, we explore linear programming and optimization methods that enable reliable decision-making within constraints. Show notes:Linear programming allows us to solve problems with multiple constraints, like finding optimal flights that meet budget requirementsThe Lagrange multiplier method helps find optimal solutions within constraints by reformulating utility functionsCombinatorial optimization handles discrete choices like selecting specific flights rather than continuous variablesDynamic programming techniques break complex problems into manageable subproblems to find solutions efficientlyMixed integer programming combines continuous variables (like budget) with discrete choices (like flights)Neurosymbolic approaches potentially offer conversational interfaces with the reliability of mathematical solversUnlike pattern-matching LLMs, mathematical optimization guarantees solutions that respect user constraintsMake sure you check out Part 1: Mechanism design and Part 2: Utility functions. In the next episode, we'll pull all of the components from these three episodes to demonstrate a complete travel agent AI implementation with code examples and governance considerations.What we're reading:Burn Book - Kara Swisher, March 2025Signal and the Noise - Nate Silver, 2012Leadership in Turbulent Times - Doris Kearns GoodwinWhat did you think? Let us know.Do you have a question or a discussion topic for the AI Fundamentalists? Connect with them to comment on your favorite topics: LinkedIn - Episode summaries, shares of cited articles, and more. YouTube - Was it something that we said? Good. Share your favorite quotes. Visit our page - see past episodes and submit your feedback! It continues to inspire future episodes.

Dr. Eduardo Cardona-Sanclemente, integrative medicine doctor with a focus on Ayurveda, has joined me (again) to share his brilliant insights. Please join us as we discuss: the inspiration behind his book: Ayurveda for Obesity and Gut Health his insights on the body/mind connection his philosophies on being grounded to nature an understanding of fat cells and so much more! Welcome to The Healing Place Podcast! I am your host, Teri Wellbrock. You can listen in on Pandora, Apple Podcasts, Spotify, iHeartRadio, Deezer, Amazon Music, and more, or directly on my website at www.teriwellbrock.com/podcasts/. You can also catch our insightful interview on YouTube. Bio: Dr. Eduardo Cardona-Sanclemente Dr. Eduardo Cardona-Sanclemente's medical and scientific career spans professorships and senior scientific research posts at a number of Europe's most distinguished medical schools and universities including The William Harvey Research Institute (WHRI, London); St. Bartholomew's Hospital Medical College (London); King's College London; Institut Pasteur (Paris); Salpêtrière Hospital (Paris); Institut Biomedical des Cordeliers (Paris); Sorbonne University (Paris) and the University of Perugia Medical School (Italy), In addition he has held Visiting Professors at AVP Hospital, Coimbatore (India) and S.D.M. College of Ayurveda, Udupi (India) where he taught postgraduate students, including in one of his specialism, lipid metabolism. He is an external supervisor for PhD students at Queen Mary University of London (QMUL). After graduating in Medical Sciences, he completed his Masters in Clinical Biochemistry and his PhD in the “Mechanism of Intake of Neurotransmitters” at the Sorbonne University (Paris). Following several years of medical and scientific research and published papers on the metabolism of cholesterol, he was awarded the Docteur d'Etat (Doctor of Science) in “Physiopathology of Nutrition by the Sorbonne, with the highest distinction (Très Honorable). Dr Cardona joined the WHRI in London under the Nobel laureate Sir John Vane, working with Professor Gustav Born on various aspects of Pathopharmacology. In parallel to his allopathic medical research and teaching, he has been studying and practicing integrative and Ayurvedic medicine for decades and holds a Masters in Ayurvedic Medicine from Middlesex University, UK, having completed internships at AVP Hospital Coimbatore and Udupi, India (2,000 hours+). He is a certified Ayurvedic Doctor by the National Ayurvedic Medical Association, USA (certified professional level) and has recently taught graduate students in Ayurveda at Bastyr University, Seattle and the University of New Mexico, NM. He is also a Member of the NHS Directory of Complementary & Alternative Practitioners, UK and presided for several years the Research Director of the Ayurvedic Professional Association (APA, UK). Dr. Cardona-Sanclemente is a Fellow of The Royal Society of Medicine (UK) and a Professional Member of the College of Medicine (UK). At present, he lives in Berkeley, CA and runs his private practice, and lectures nationally and internationally on Ayurveda, sharing his decades of experience at the interface of allopathic, integrative and Ayurvedic medical topics. He has delivered numerous engagements in building awareness and integration of the knowledge, efficacy and cost-effectiveness of Ayurveda and Integrative Medicine through developing health-related programs with academic, medical and non-profits organizations as part of his work for the integration and inclusion of minorities. Dr Cardona-Sanclemente has recently completed a book, due to be published in September 2020, on Ayurveda for Depression. He is fluent in English, Spanish, French and Italian. ​Website: https://www.eduardocardona.com/ Teri's #1 best-selling book and #1 new-release book can be found here.

Fat Loss & Metabolism with Dr. Ben Bikman Challenging the dogma surrounding heart disease. (1:32) Is there a connection between dementia and heart disease? (12:05) Strength training and Alzheimer's. (17:49) Learning something new helps put off dementia. (22:45) The connection between insulin resistance and your body's inability to fight off infection. (25:17) We put TOO much attention on total cholesterol. (27:55) Fat cells dynamics explained. (30:13) Why your metabolism is EXTREMELY complex. (44:14) Mitochondrial uncoupling. (48:51) Ketones and athletic performance. (55:39) The problem with DNP. (58:11) Why he is a HUGE advocate of creatine. (1:01:03) The brain loves ketones. (1:04:33) Keep your running shoes in the closet, GO STRENGTH TRAIN! (1:05:32) The metabolic origins of chronic disease. (1:08:10) How GLP-1s are being overused and the proper way to use them. (1:14:48) The resurgence of religion. (1:37:57) As a scientist, did he ever doubt his faith? (1:41:28) The most profound moment of his life. (1:45:51) Related Links/Products Mentioned Why We Get Sick: The Hidden Epidemic at the Root of Most Chronic Disease - and How to Fight It – Book by Dr. Benjamin Bikman How Not to Get Sick: A Cookbook and Guide to Prevent and Reverse Insulin Resistance, Lose Weight, and Fight Chronic Disease – Book by Dr. Benjamin Bikman Unlock sharper focus and support long-term brain health with Ketone-IQ—clean brain fuel for deep work, mental clarity, and sustained energy with no crash. Get 30% off your subscription, plus a free gift with your second shipment at https://ketone.com/MINDPUMP June Special: Shredded Summer Bundle or Bikini Bundle 50% off! ** Code JUNE50 at checkout ** Most heart attack patients' cholesterol levels did not indicate cardiac risk Study: Doubling Saturated Fat in the Diet Does Not Increase Saturated Fat in Blood Insulin signal transduction pathway Mind Pump #1922: Fatphobia & Other Lies That Are Keeping You Fat, Unhealthy & Sick Diabulimia: Why This Eating Disorder Is So Dangerous for People with Diabetes Harris-Benedict equation - Wikipedia Mitochondrial Uncoupling: A Key Controller of Biological Processes in Physiology and Diseases DNP (Dinitrophenol): Overview, Mechanism, and Risks Mind Pump #2497: The Amazing & Weird Side Effects of Creatine Muscle strength and fitness linked to reduction in cancer deaths Fighting Cancer By Putting Tumor Cells On A Diet - NPR Healthy Weight Loss Maintenance with Exercise, Liraglutide, or Both Combined Attenuated GLP-1 secretion in obesity: cause or consequence? Mind Pump #2597: Before You Take Ozempic, Wegovy, or Mounjaro Listen to This! Liraglutide modulates lipid metabolism via ZBTB20-LPL pathway Mind Pump #872: Dr. Warren Farrell- The Boy Crisis Mind Pump Podcast – YouTube Mind Pump Free Resources Featured Guest/People Mentioned Benjamin Bikman (@benbikmanphd) Instagram Website Zach Bitter (@zachbitter) Instagram  Thomas N. Seyfried (@thomasseyfriedbc) Instagram Warren Farrell, PhD (@drwarrenfarrell) X/Twitter  

Ten Years of the International Residual Mechanism for Criminal Tribunals: Achievements and Challenges

The Alan Cox ShowSee omnystudio.com/listener for privacy information.

The Alan Cox Show

437: Neal McDonough—Clear the Mechanism The perennial character actor villain turned leading man drops by to talk about the first film where he finally gets to kiss the girl at the end, The Last Rodeo—and that girl is played by his wife, Ruvé. Coincidence? Not a chance. That's the only way Neal would do it. Neal also discusses how he secured a return to Taylor Sheridan's Tulsa Kings, why he thought Sylvester Stallone might deck him on set, and the greatest career advice Clint Eastwood gave him. Today's episode is sponsored by CompanyCam.com Jobsite photo tools to manage work from anywhere. American-Giant.com/MIKE Use code MIKE to get 20% off your order. skillsusa.org/mike Join the skilled trade movement! Watch People You Should Know on Mike's YouTube Channel

Tetanus has probably been around for most of human history, or even longer. But it’s preventable today thanks to vaccines. Research: "Emil von Behring." Notable Scientists from 1900 to the Present, edited by Brigham Narins, Gale, 2008. Gale In Context: Science, link.gale.com/apps/doc/K1619001490/GPS?u=mlin_n_melpub&sid=bookmark-GPS&xid=464250e5. Accessed 17 Apr. 2025. Breasted, J.H., translator. “OIP 3. The Edwin Smith Surgical Papyrus, Volume 1: Hieroglyphic Transliteration, Translation, and Commentary.” Oxford University Press. 1930. Chalian, William. “An Essay on the History of Lockjaw.” Bulletin of the History of Medicine, FEBRUARY, 1940, Vol. 8, No. 2. Via JSTOR. https://www.jstor.org/stable/44446242 Emil von Behring: The founder of serum therapy. NobelPrize.org. Nobel Prize Outreach 2025. Thu. 17 Apr 2025. https://www.nobelprize.org/prizes/medicine/1901/behring/article/ Galassi, Francesco Maria et al. “Tetanus: historical and palaeopathological aspects considering its current health impact.” Journal of preventive medicine and hygiene vol. 65,4 E580-E585. 31 Jan. 2025, doi:10.15167/2421-4248/jpmh2024.65.4.3376 George, Elizabeth K. “Tetanus (Clostridium tetani Infection).” StatPearls. January 2025. https://www.ncbi.nlm.nih.gov/books/NBK482484/ Hippocrates. “VI. Diseases, Internal Affections.” Harvard University Press. 1988. Jean-Marc Cavaillon, Historical links between toxinology and immunology, Pathogens and Disease, Volume 76, Issue 3, April 2018, fty019, https://doi.org/10.1093/femspd/fty019 Jones CE, Yusuf N, Ahmed B, Kassogue M, Wasley A, Kanu FA. Progress Toward Achieving and Sustaining Maternal and Neonatal Tetanus Elimination — Worldwide, 2000–2022. MMWR Morb Mortal Wkly Rep 2024;73:614–621. DOI: http://dx.doi.org/10.15585/mmwr.mm7328a1 Kaufmann, Stefan H E. “Remembering Emil von Behring: from Tetanus Treatment to Antibody Cooperation with Phagocytes.” mBio vol. 8,1 e00117-17. 28 Feb. 2017, doi:10.1128/mBio.00117-17 Kreston, Rebecca. “Tetanus, the Grinning Death.” Discover. 9/29/2015. https://www.discovermagazine.com/health/tetanus-the-grinning-death Milto, Lori De, and Leslie Mertz, PhD. "Tetanus." The Gale Encyclopedia of Public Health, edited by Brigham Narins, 2nd ed., vol. 2, Gale, 2020, pp. 1074-1076. Gale In Context: Environmental Studies, link.gale.com/apps/doc/CX7947900274/GPS?u=mlin_n_melpub&sid=bookmark-GPS&xid=a44bc544. Accessed 14 Apr. 2025. Milto, Lori De, and Leslie Mertz, PhD. "Tetanus." The Gale Encyclopedia of Public Health, edited by Brigham Narins, 2nd ed., vol. 2, Gale, 2020, pp. 1074-1076. Gale In Context: Environmental Studies, link.gale.com/apps/doc/CX7947900274/GPS?u=mlin_n_melpub&sid=bookmark-GPS&xid=a44bc544. Accessed 15 Apr. 2025. National Institutes of Health. “Tetanus.” https://history.nih.gov/display/history/Tetanus Ni, Maoshing. “The Yellow Emperor's Classic of Medicine: A New Translation of the Neijing Suwen with Commentary.” Shambhala. 1995. Smithsonian. “The Antibody Initiative: Battling Tetanus.” https://www.si.edu/spotlight/antibody-initiative/battling-tetanus Sundwall, John. “Man and Microbes.” Illustrated lecture given under the auspices of the Kansas Academy of Science, Topeka, January 12, 1917. https://archive.org/details/jstor-3624335/ The Nobel Prize in Physiology or Medicine 1901. NobelPrize.org. Nobel Prize Outreach 2025. Thu. 17 Apr 2025. https://www.nobelprize.org/prizes/medicine/1901/summary/ Tiwari, Tejpratap S.P. et al. “Chapter 21: Tetanus.” CDC Pink Book. https://www.cdc.gov/pinkbook/hcp/table-of-contents/chapter-21-tetanus.html Von Behring, Emil and Kitasato Shibasaburo. “The Mechanism of Immunity in Animals to Diphtheria and Tetanus.” Immunology. 1890. http://raolab.org/upfile/file/20200612164743_201234_56288.pdf War Office Committee for the Study of Tetanus. “Memorandum on Tetanus.” Fourth Edition. 1919. https://archive.org/details/b32171201/ World Health Organization. “Tetanus.” 7/12/2024. https://www.who.int/news-room/fact-sheets/detail/tetanus See omnystudio.com/listener for privacy information.