Podcasts about transportin

Keith Smith, President of Vonco Products, a leader in medical device packaging and contract manufacturing. Keith has spent years refining the science behind sterile packaging solutions, ensuring that medical products survive extreme conditions, from freezing temperatures to high-pressure airline transportIn this episode, we uncover why medical packaging is far more than just a box, it's a critical component in ensuring safety, sterility and regulatory compliance. Keith shares real-world failures where improper packaging led to catastrophic outcomes, the rigorous testing required to meet global standards and how manufacturers can avoid costly recalls. We also discuss the benefits and pitfalls of outsourcing medical device production, why some companies thrive with contract manufacturing while others struggle and Keith's own entrepreneurial journey from acquiring Vonco to leading it into the medical device spaceTimestamps:[00:00:27] Why Medical Device Packaging is Critical for Patient Safety[00:02:30] The Hidden Dangers of Poorly Designed Packaging[00:05:46] Surviving Extreme Conditions: Cold, Heat & Pressure[00:07:02] Global Packaging Regulations: Why Standards Vary by Region[00:10:16] The Pros & Cons of Outsourcing Medical Device Manufacturing[00:13:43] From Food Packaging to MedTech: The Evolution of Vonco[00:20:54] Leadership & Entrepreneurship: Lessons from Running a BusinessGet in touch with Keith Smith - https://www.linkedin.com/in/keith-smith-725508b/ Get in touch with Karandeep Badwal - https://www.linkedin.com/in/karandeepbadwal/ Follow Karandeep on YouTube - https://www.youtube.com/@KarandeepBadwalSubscribe to the Podcast

Si tu perro te sigue por toda la casa, te busca incesantemente y no puede soportar un minuto solo, ¡no te preocupes! ¡No estás solo en esta lucha! En este episodio, me lanzo a descubrirte el oscuro y misterioso origen de esta ansiedad por separación, ¡y créeme que no es lo que todos creen! ¡Deja … Episodio #219: Ansiedad por separación y transportin Leer más » The post Episodio #219: Ansiedad por separación y transportin first appeared on Xila´s.

Transportin'

01. MotorSport - Migos ft. Nicki Minaj & Cardi B [0:00]02. Goosebumps - Travis Scott ft. Kendrick Lamar [4:07]03. Crew - GoldLink ft. Brent Faiyaz & Shy Glizzy [7:22]04. Drowning [Water] - A Boogie Wit Da Hoodie ft. Kodak Black [9:47]05. Bad And Boujee - Migos ft. Lil Uzi Vert [12:58]06. Bodak Yellow - Cardi B [17:41]07. Come Closer - WizKid ft. Drake [21:13]08. Unforgettable - French Montana ft. Swae Lee [24:10]09. First Day Out - Tee Grizzley [27:55]10. Look At Me - Xxxtentacion [30:41]11. Element. - Kendrick Lamar [31:40]12. Transportin' - Kodak Black [34:19]13. No Limit [Remix] - G-Eazy ft. A$AP Rocky, Cardi B, French Montana, Juicy J & Belly [36:41]14. Plain Jane - A$AP Ferg [42:24]15. Bounce Back - Big Sean [45:33]16. Flipmode - Fabolous ft. Velous & Chris Brown [48:33]17. Moves - Big Sean [52:23]18. Rake It Up - Yo Gotti ft. Nicki Minaj [54:31]19. iSpy - Kyle ft. Lil Yachty [58:43]20. Black Beatles - Rae Sremmurd ft. Gucci Mane [1:02:07]

01. MotorSport - Migos ft. Nicki Minaj & Cardi B [0:00] 02. Goosebumps - Travis Scott ft. Kendrick Lamar [4:07] 03. Crew - GoldLink ft. Brent Faiyaz & Shy Glizzy [7:22] 04. Drowning [Water] - A Boogie Wit Da Hoodie ft. Kodak Black [9:47] 05. Bad And Boujee - Migos ft. Lil Uzi Vert [12:58] 06. Bodak Yellow - Cardi B [17:41] 07. Come Closer - WizKid ft. Drake [21:13] 08. Unforgettable - French Montana ft. Swae Lee [24:10] 09. First Day Out - Tee Grizzley [27:55] 10. Look At Me - Xxxtentacion [30:41] 11. Element. - Kendrick Lamar [31:40] 12. Transportin' - Kodak Black [34:19] 13. No Limit [Remix] - G-Eazy ft. A$AP Rocky, Cardi B, French Montana, Juicy J & Belly [36:41] 14. Plain Jane - A$AP Ferg [42:24] 15. Bounce Back - Big Sean [45:33] 16. Flipmode - Fabolous ft. Velous & Chris Brown [48:33] 17. Moves - Big Sean [52:23] 18. Rake It Up - Yo Gotti ft. Nicki Minaj [54:31] 19. iSpy - Kyle ft. Lil Yachty [58:43] 20. Black Beatles - Rae Sremmurd ft. Gucci Mane [1:02:07]

Kings Of The Kitchen : Reggaeton, Urbano, Dembow, Hip-Hop Mixtape (2018) by DJ Suelto 1. Messiah Ft Bad Bunny & Tory Lane – Give It Up 2. 2 Chainz – Good Drank 3. Dr Dre – Next Episode 4. Meek Mill Ft Tory Lane – Litty 5. Bad Bunny – Otra Vez 6. Migos – Fucking Up Profits 7. Rich The Kid Ft Kendrick Lamar – New Freezer 8. Big Sean Ft Metro Boomin & Travis Scott – Go Legend 9. Drake – Diplomatic Immunity 10. Chris Jeday x Ozuna x Brytiago – Bipolar 11. Lirico En La Casa Ft Atomic – Muevelo 12. El Alfa – Suave 13. Bulova – Me Desacate Y Prendi 14. El Mayor – Tito Rojas 15. Ceky Viciny – Klok Con Klok 16. Musicologo – Tea Chan 17. Lapiz Conciente & Musicologo – Limonada Coco (Remix) 18. Bad Bunny – Me Rolie 19. Lil Pump Ft Bad Bunny – Gucci Gang (Remix) 20. Spiff TV Ft Anuel AA, Bad Bunny & Future – Thinkin’ 21. Tory Lanez – Shooters 22. Migos – Bad & Boujee 23. Future – Draco 24. Gucci Mane Ft Migos & Lil Yachty – Solitaire 25. Bloccboy JB – Rover 2.0 26. Bloccboy JB Ft Drake – Look Alive (Remix) 27. Anna Mvze – Look Alive (Mvze Remix) 28. Natti Natasha Ft Bad Bunny – Amantes De Una Noche 29. XXXTentacion – I Don’t Even Speak Spanish LOL 30. Migos – Gang Gang 31. Jacquees & Dej Loaf – At The Club 32. Rich The Kid – Plug Walk 33. Kodak Black – Transportin’ 34. 6IX9INE – Kooda 35. Big Sean – What A Year 36. Cardi B – Bickenhead 37. DJ Esco Ft Future & OT Genasis – Bring Em Out 38. Ozuna Ft Ele A El Dominio – Balenciaga 39. G4 Boyz – Patek Phillippe (Tory Lanez Remix) 40. Kay Rock Ft Kendrick Lamar, Future & James Blake – King’s Dead 41. Remy Ma Ft Lil Kim – Wake Me Up 42. Zay Hilfigerr – Juju On That Beat 43. Drake – Child’s Play 44. Los Teke Teke – Deja Tu Estres 45. Crazy Design – Ella Eh 46. Lyon La Difrencia Ft KO El Mas Completo – Reebok O Nike 47. MC Fioti Ft Bad Bunny – Bum Bum Tam Tam 48. Messiah – Bien De To 49. Nejo – Flow De Kilero 50. De La Ghetto, Arcangel, Revol, Bad Bunny & J Balvin – Dime

01. Turn Me On - Kevin Lyttle [0:00] 02. Questions - Chris Brown [1:50] 03. Havana - Camila Cabello ft. Young Thug [3:37] 04. Maria Maria - Santana ft. The Product G&B [6:45] 05. Wild Thoughts - DJ Khaled ft. Rihanna & Bryson Tiller [8:49] 06. Lemon - N.E.R.D & Rihanna [12:06] 07. Transportin' - Kodak Black [14:35] 08. No Limit - G-Eazy ft. A$AP Rocky & Cardi B [16:55] 09. Plain Jane - A$AP Ferg [20:18] 10. Ric Flair Drip - Offset & Metro Boomin [22:53] 11. The Way Life Goes [Remix] - Lil Uzi Vert ft. Nicki Minaj [25:24] 12. XO Tour Llif3 - Lil Uzi Vert [28:59] 13. Patek Water - Future & Young Thug ft. Offset [31:28] 14. Relationships - Young Thug & Future [34:20] 15. Pills & Automobiles - Chris Brown ft. Yo Gotti, A Boogie & Kodak Black [37:07] 16. Rake It Up - Yo Gotti ft. Nicki Minaj [41:40] 17. Bodak Yellow - Cardi B [45:51] 18. Gucci Gang - Lil Pump [49:22] 19. Bank Account - 21 Savage [51:11] 20. Roll In Peace - Kodak Black ft. Xxxtentacion [54:45] 21. I Get The Bag - Gucci Mane ft. Migos [57:53] 22. MotorSport - Migos ft. Cardi B & Nicki Minaj [1:01:14] 23. Congratulations - Post Malone ft. Quavo [1:06:00] 24. Rockstar - Post Malone ft. 21 Savage [1:09:20] 25. Sky Walker - Miguel ft. ft. Travis Scott [1:12:40] 26. The Weekend - SZA [1:15:53]

This is episode 7 of our podcast where we will be giving all the flava from music, entertainment to fashion. Today we will be discussing about VMAs Line Up Artists and Yo Gotti "Rake It Up" music video. Subscribe to our page now! Follow us on Instagram & Twitter: @KoncreteFlava

Neurodegenerative diseases such as Alzheimer´s disease, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are defined by progressive and selective loss of neurons. With increasing age the risk of developing a neurodegenerative disease exponentially rises. To date these diseases are untreatable, imposing a significant medical, social and financial burden onto our ageing society. Typical features of neurodegenerative diseases are abnormal aggregation of a disease characterizing protein and its deposition in pathological inclusions. A unifying feature in the majority of ALS cases and several subtypes of FTD is the pathological deposition of the TAR DNA-binding protein of 43kDa (TDP-43) or the Fused in Sarcoma (FUS) protein. Furthermore, stress granule (SG) marker proteins are consistently detected in FUS inclusions, suggesting that SGs might be involved in the formation of FUS inclusions. However, whether pathologic TDP-43 inclusions contain SG marker proteins is still controversially discussed. In this thesis I demonstrate that cytosolically mislocalized full-length TDP-43 is recruited into SGs, whereas C-terminal fragments of TDP-43 (TDP-CTFs) fail to localize to SGs. In accordance with these cell culture data, spinal cord inclusions in ALS and FTD patients contain full-length TDP-43 and SG marker proteins. In contrast, hippocampal inclusions are enriched for TDP-CTFs but are SG marker-negative. Thus, the protein composition of TDP-43 inclusions determines whether SG marker proteins are co-deposited in TDP-43 inclusions or not. By analyzing the prerequisites for SG recruitment of TDP-43 and FUS, I demonstrate that cytosolic mislocalization of TDP-43 and FUS is required for their localization in SGs. Additionally, I found that both proteins have the same requirements for SG recruitment, as their main RNA-binding domain and a glycine-rich domain are essential for SG localization. A detailed analysis of the protein composition of FUS inclusions in ALS and FTD cases unveiled that FUS inclusions in FTD cases contain not only FUS, but all FET (FUS, Ewing sarcoma protein (EWS), TATA binding protein-associated factor 15 (TAF15)) family proteins. Here, I provide evidence that this cytosolic deposition of FET proteins can be mimicked in cultured cells by inhibition of Transportin-mediated nuclear import, which causes cytosolic mislocalization of all FET proteins and recruitment of these proteins in SGs. In contrast to FTD cases, FUS inclusions in ALS cases contain only FUS, but not EWS and TAF15. In line with that, I show that ALS-associated FUS mutations result in cytosolic mislocalization of FUS that is upon subsequent cellular stress sequestered into SGs. These SGs then contain only FUS but not EWS or TAF15, demonstrating that mutant FUS is unable to co-sequester EWS or TAF15. In addition, I contributed to two studies that revealed that nuclear import defects are involved in the pathogenesis of ALS and FTD. ALS associated FUS mutations are frequently located within the proline-tyrosine nuclear localization signal (PY-NLS) of FUS and thus disrupt Transportin-mediated nuclear import and cause cytosolic mislocalization of FUS. EWS and TAF15 also contain a PY-NLS and thus are imported into the nucleus via Transportin. This interaction between Transportin and FET proteins can be modulated by arginine methylation that reduces Transportin binding. In FTD patients with FUS inclusions, this post-translational modification seems to be defective, as FUS inclusions in these cases contain hypomethylated FUS. Taken together, these data provide evidence that nuclear import defects and sequestration of FUS and TDP-43 in SGs are consecutive steps in the pathogenesis of ALS and several subtypes of FTD.