Podcasts about ftd

Check out our new Stretford Paddock Merchandise: https://stretfordpaddock.store/ Join Jay, Joe and Stephen Howson as they discuss the Manchester Derby and a few of the positives Ruben Amorim and his side can take into the game! Join us for Off The Bar... Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Chapters: 0:00 - Intro 0:58 - International Break 2:35 - 'Domestic Weighted Tilt' 9:31 - PIBBBAF 12:23 - Pep Vs Amorim 20:23 - New Look City 25:15 - United Midfield 30:40 - Goalkeeper 36:20 - Benjamin Sesko 42:24 - United Fixtures 49:02 - Chelsea Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

Go to https://surfshark.com/paddock or use code PADDOCK at checkout to get 4 extra months of Surfshark VPN! Manchester United have switched gears when it comes to bringing in new types of players, from a time where we would sign players that 'suit the manager', to signing versatile players to adapt should the end of Amorim's tenure come around! Join Joe, Jay and Ronaldo Brown for The Paddock Podcast LIVE! Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

Join Stephen Howson, Jay Motty & Joe Smith as they look at the footballing world's 'firsts' and record breakers! Join us LIVE for The Brew! Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

An event to support ALS and FTD research gets underway in New Prague tomorrow. The New Prague Area Hops for Hope Community Fundraiser is a fun way for the community to come together and support efforts to find treatment and one day a cure for the disease. Organizers Marc and Julie Smith join the show to talk about what people can expect and how you can help.

An event to support ALS and FTD research gets underway in New Prague tomorrow. The New Prague Area Hops for Hope Community Fundraiser is a fun way for the community to come together and support efforts to find treatment and one day a cure for the disease. Organizers Marc and Julie Smith join the show to talk about what people can expect and how you can help.

Laurie Whitwell is back to discuss whether Ruben Amorim's job is secure this season and exactly how close was he to leaving after the Grimsby Defeat?! Join Joe, Jay and Laurie for Inside United! Read Laurie's articles here! - https://www.nytimes.com/athletic/author/laurie-whitwell/ Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Chapters: 0:00 - Intro 1:40 - Benjamin Sesko 8:25 - Mount & Cunha 16:10 - Danny Welbeck 21:30 - Project 90 25:40 - Andre Onana 29:20 - Senne Lammens 36:10 - Midfield Dilemma 50:20 - Amorim Leaving? 58:10 - Sales & Outgoings Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

Man United have had a confusing start to their season so far... A string of results that don't equate to performances and a humbling loss in the cup has forced some negative opinions surrounding Amorim and his squad, but looking at the bigger picture there are plenty of positives to take! Join Joe, Jay, Adam McKola and Ronnie for the Paddock Podcast! Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

Hologram police officer working?... Organized Home Depot Crime ring busted… Kid on Spectrum gets perp walked by Meijers… A look at lotto… Burning Man struggling / Orgy Dome Destroyed… Youtube and Fox still fighting?... Melania laughs at Vanity Fair offer… The Waterfront no season two… www.blazeunlimited.com/jeffy Promo code: BLAZE50 / Forty Dollars off for limited time… Email: ChewingTheFat@theblaze.com Who Died Today: Natalia “Natasha” Nagovitsina 47… Bruce Willis dealing with FTD… www.kekski.com Crumble CEO comes out… Joke of The Day… Learn more about your ad choices. Visit megaphone.fm/adchoices

We are discussing perspective changes in neurology genetics with the crossover of the APOE gene in neuro and cardio as well as telehealth for neurology predictive testing. Segment 1: Is it time for a paradigm shift? Inclusion of APOE  on genetic dyslipidemia panels.   Emily Brown is a certified genetic counselor at the Center for Inherited Heart Disease at Johns Hopkins Hospital. She graduated from the University of Maryland Genetic Counseling Program in 2014 and has practiced in cardiology for the past 10 years. Her main areas of interest include dyslipidemias, and she is a member of the National Lipid Association.   Hannah Ison is a cardiovascular genetic counselor at the Stanford Center for Inherited Cardiovascular Disease. She received her Master's in Medical and Molecular Genetics from Indiana University in 2018, and returned home to California to begin her career. Her primary clinical interest includes working with patients who have inherited lipid conditions in both the adult and pediatric setting. A large part of her role has been focused on developing a Pediatric Lipid Clinic at the Stanford Children's Hospital, allowing her to care for patients across the generations. Hannah was the co-chair of the Dyslipidemia Working Group through the cardiovascular SIG from 2020-2024 where she worked with members to develop dyslipidemia resources. In addition to her work in the lipid space, she also provides inpatient and outpatient genetic counseling to patients with isolated congenital heart disease, and enjoys participating in various research opportunities.    In this segment we discuss: - APOE's relevance in both Alzheimer's and cardiovascular disease - Counseling strategies for APOE alleles (ε2, ε3, and ε4), including penetrance, lifestyle modification, and exploration of risk for conditions and symptoms external to Alzheimer's - Case studies highlighting APOE's diagnostic, variant, and treatment insights - The need for standardization, education, and reframing of APOE testing in practice Segment 2: Patient-reported outcomes for remote and in-person visits for genetic counseling in adult neurology.   Rachel A. Paul, MS, CGC and Laynie Dratch, ScM, CGC are board-certified genetic counselors who specialize in adult neurogenetics and work with the Penn Neurogenetics Therapy Center team in Philadelphia, PA (https://www.linkedin.com/company/penn-neurogenetics-therapy-center).   Rachel provides clinical and research genetic counseling services for the Division of Movement Disorders at the University of Pennsylvania. Her research interests include genetic screening for clinical trials access, remote/telemedicine genetic services, and motivations/barriers for genetics utilization. She graduated cum laude from Temple University in Philadelphia, previously worked as a genetic counseling assistant (GCA) for the Penn neurogenetics program, and completed her training with the Arcadia University (now University of Pennsylvania) Genetic Counseling Program.   Laynie's clinical focus includes frontotemporal degeneration (FTD) spectrum disorders, amyotrophic lateral sclerosis (ALS), and other neurodegenerative conditions. Her research interests include the lived experiences of at-risk individuals, predictive genetic testing considerations, and genetic counseling access and service delivery. She graduated summa cum laude from Colgate University with a BA in neuroscience and a minor in psychology, and completed her genetic counseling masters training at the Johns Hopkins University and the National Institutes of Health.   In this segment we discuss: - How COVID-19 pushed neurogenetics counseling from in-person to telehealth. - Why patient satisfaction stayed high across both formats, with video outperforming phone. - What drives visit preferences—travel, tech comfort, privacy, and clinical needs. - Future research to refine protocols, improve access, and explore broader applications.   Would you like to nominate a JoGC article to be featured in the show? If so, please fill out this nomination submission form here. Multiple entries are encouraged including articles where you, your colleagues, or your friends are authors.   Stay tuned for the next new episode of DNA Dialogues! In the meantime, listen to all our episodes Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “DNA Dialogues”.    For more information about this episode visit dnadialogues.podbean.com, where you can also stream all episodes of the show. Check out the Journal of Genetic Counseling here for articles featured in this episode and others.    Any questions, episode ideas, guest pitches, or comments can be sent into DNADialoguesPodcast@gmail.com.    DNA Dialogues' team includes Jehannine Austin, Naomi Wagner, Khalida Liaquat, Kate Wilson and DNA Today's Kira Dineen. Our logo was designed by Ashlyn Enokian. Our current intern is Stephanie Schofield.

Sign up to FotMob here: https://click.fotmob.com/974672417/StretfordPaddock After the opening two games of the season, Laurie Whitwell is back to give his insight into some recent controversy surrounding Kobbie Mainoo - who has yet to feature this season! Also, we have more exclusives on incomings and outgoings... Laurie joins Joe Smith for this episode of Inside United... Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

Join us LIVE with Jay and Joe for the immediate post-match review of Manchester United away at Blundell Park Vs Grimsby Town! Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

When Frontotemporal Dementia (FTD) entered their lives, everything changed for Nanci Anderson and her daughters, Lindsay Early and Emily Anderson. In this conversation, they open their hearts about the long and confusing road to Gary's diagnosis, the challenges of caregiving, and the deep grief of watching someone you love slip away too soon. They also share the turning point, when they chose to honor Gary by creating Gary's FUB Team and raising awareness through advocacy and community. This is a story of heartbreak and resilience, of carrying love forward, and of finding purpose in the face of loss.   And here's where you can step in. Gary's FUB Team is hosting their annual fundraising event, September 22nd, to benefit AFTD. This is an evening filled with community, storytelling, and hope. Every ticket, every donation, every act of support moves us closer to better care, greater awareness, and the possibility of ending FTD. If you'd like to attend, contribute, or simply stand alongside families like Nanci and Lindsay's, you can visit garysfubteam.simpletix.com. Whether you show up in person or from afar, your support matters more than you know! Connect with Gary's FUB Team on Instagram and Facebook @garysfubteam To learn more about The Association for Frontotemporal Degeneration visit https://www.theaftd.org/   We are not medical professionals and are not providing any medical advice. If you have any medical questions, we recommend that you talk with a medical professional of your choice. willGather has taken care in selecting its speakers but the opinions of our speakers are theirs alone. Thank you for your continued interest in our podcasts. Please follow for updates, rate & review! For more information about our guest, podcast & sponsorship opportunities, visit www.willgatherpodcast.com Instagram: @willgather Facebook: WillGather   Thank you our sponsor, Zinnia TV. We invite you to use the code GATHER20 for 20% off an annual subscription HERE.

Our conversation with Susan Dickinson, Chief Executive Officer of the Association for Frontotemporal Degeneration (AFTD), explores frontotemporal dementia (FTD), a lesser known but devastating form of dementia that primarily affects behavior and executive function rather than memory. Susan helps us understand the distinctive signs of FTD, including personality changes, social inappropriateness, and diminished decision-making abilities that often appear in patients' 40s and 50s — decades earlier than typical Alzheimer's onset. She clearly explains the critical differences between FTD and Alzheimer's disease, emphasizing why an accurate diagnosis is essential for proper treatment, family support, and planning. 

Progressive supranuclear palsy and corticobasal syndrome are closely related neurodegenerative disorders that present with progressive parkinsonism and multiple other features that overlap clinically and neuropathologically. Early recognition is critical to provide appropriate treatment and supportive care. In this episode, Teshamae Monteith, MD, FAAN speaks with Nikolaus R. McFarland, MD, PhD, FAAN, author of the article “Progressive Supranuclear Palsy and Corticobasal Syndrome” in the Continuum® August 2025 Movement Disorders issue. Dr. Monteith is the associate editor of Continuum® Audio and an associate professor of clinical neurology at the University of Miami Miller School of Medicine in Miami, Florida. Dr. McFarland is an associate professor of neurology at the University of Florida College of Medicine at the Norman Fixel Institute for Neurological Diseases in Gainesville, Florida. Additional Resources  Read the article: Progressive Supranuclear Palsy and Corticobasal Syndrome Subscribe to Continuum®: shop.lww.com/Continuum Earn CME (available only to AAN members): continpub.com/AudioCME Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the American Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Host: @headacheMD Full episode transcript available here Dr Jones: This is Dr Lyell Jones, Editor-in-Chief of Continuum. Thank you for listening to Continuum Audio. Be sure to visit the links in the episode notes for information about earning CME, subscribing to the journal, and exclusive access to interviews not featured on the podcast. Dr Monteith: Hi, this is Dr Teshamae Monteith. Today I'm interviewing Dr Nikolaus McFarland about his article on progressive supranuclear palsy and cortical basilar syndrome, which appears in the August 2025 Continuum issue on movement disorders. Welcome, how are you? Dr Farland: I'm great. Thank you for inviting me to do this. This is a great opportunity. I had fun putting this article together, and it's part of my passion. Dr Monteith: Yes, I know that. You sit on the board with me in the Florida Society of Neurology and I've seen your lectures. You're very passionate about this. And so why don't you first start off with introducing yourself, and then tell us just a little bit about what got you interested in this field. Dr Farland: I'm Dr Nicholas McFarlane. I'm an associate professor at the University of Florida, and I work at the Norman Fixel Institute for Neurological Diseases. I am a director of a number of different centers. So, I actually direct the cure PSP Center of Care and the MSA Center of Excellence at the University of Florida; I also direct the Huntington's clinic there as well. But for many years my focus has been on atypical parkinsonisms. And, you know, I've treated these patients for years, and one of my focuses is actually these patients who suffer from progressive supranuclear palsy and corticobasal syndrome. So that's kind of what this review is all about. Dr Monteith: You probably were born excited, but I want to know what got you interested in this in particular? Dr Farland: So, what got me interested in this in particular was really the disease and the challenges that's involved in it. So, Parkinson's disease is pretty common, and we see a lot of that in our clinic. Yet many times, roughly about 10 to 15% of my patients present with these atypical disorders. And they're quite fascinating. They present in different ways. They're fairly uncommon. They're complex disorders that progress fairly rapidly, and they have multiple different features. They're sort of exciting to see clinically as a neurologist. I think they're really interesting from an academic standpoint, but also in the standpoint of really trying to bring together sort of a team. We have built a multidisciplinary team here at the University of Florida to take care of these patients. They require a number of folks on that team to take care of them. And so, what's exciting, really, is the challenge of treating these patients. There are very limited numbers of therapies that are available, and the current therapies that we have often really aren't great and over time they fail. And so, part of the challenge is actually doing research. And so, there's actually a lot of new research that's been going on in this field. Recently, there's been some revisions to the clinical criteria to help diagnose these disorders. So, that's really what's exciting. The field is really moving forward fairly rapidly with a number of new diagnostics, therapeutics coming out. And hopefully we can make a real difference for these patients. And so that's what really got me into this field, the challenge of trying to treat these patients, help them, advocate for them and make them better. Dr Monteith: And so, tell me what the essential points of this article. Dr Farland: So, the essential points, really, of this article is: number one, you know, just to recognize the new clinical criteria for both PSP and corticobasal syndrome, the diagnosis for these disorders or the phenotypic spectrum has really expanded over the years. So, we now recognize many different phenotypes of these disorders, and the diagnosis has gotten fairly complicated. And so, one of the goals of this article was to review those new diagnostic criteria and the different phenotypic ways these diseases present. I wanted to discuss, also, some of the neuropathology and clinicopathological overlap that's occurred in these diseases as well as some of the new diagnostic tests that are available. That's definitely growing. Some of the new studies that are out, in terms of research and clinical trials. And then wanted to review some of the approaches for treatment for neurologists. Particularly, we're hoping that, you know, this article educates folks. If you're a general neurologist, we're hoping that recognizing these diseases early on will prompt you to refer these patients to specialty clinics or movement disorder specialists early on so they can get appropriate care, confirm your diagnosis, as well as get them involved in trials if they are available. Dr Monteith: And how has the clinical criteria for PSP and cortical basilar syndrome changed? Dr Farland: I think I already mentioned there's been an evolution of the clinical criteria for PSP. There's new diagnostic criteria that were recently published, and it recognizes the multiple clinical phenotypes and the spectrum of the disease that's out there, which is much broader than we thought about. Corticobasal clinical criteria are the Dr Armstrong criteria from 2013. They have not been updated, but they are in the works of being updated. But it does recognize the classic presentation of corticobasal syndrome, plus a frontal executive predominant and then a variant that actually overlaps with PSP. So, there's a lot more overlap in these two diseases than we originally recognized. Dr Monteith: And so, you spoke a bit about FTD spectrum. So why don't you tell us a little bit about what that is? I know you mentioned multiple phenotypes. Dr Farland: What I really want to say is that both PSP and corticobasal syndrome, they're relatively rare, and what- sort of as to common features, they both are progressive Parkinson disorders, but they have variable features. While they're commonly associated with Parkinson's, they also fit within this frontotemporal lobar spectrum, having features that overlap both clinically and neuropathologically. I just want folks to understand that overlap. One of this pathological overlap here is the predominant Tau pathology in the brain, an increasing recognology- recognition of sort of the pathological heterogeneity within these disorders. So, there's an initial description, a classic of PSP, as Richardson syndrome. But now we recognize there are lots of different features to it and there are different ways it presents, and there's definitely a lot of clinical pathological overlap. Dr Monteith: Why don't we just talk about some red flags for PSP? Dr Farland: Yeah, sure. So, some of the red flags for PSP and even corticobasal syndrome are: number one is rapid progression with early onset of falls, gait difficulty, falling typically backwards, early speech and swallow problems that are more prominent than you see in Parkinson's disease, as well as eye gaze issues. So, ocular motor features, particularly vertical gaze palsy. In particular what we talk about is the supranuclear gaze palsy, and one of the most sensitive features that we've seen with these is downgaze limitation or slowed downgaze, and eventually a full vertical gaze palsy and followed supranuclear gaze palsy. So, there's some of the red flags that we see. So, while we think about the lack of response to levodopa frequently as something that's a red flag for Parkinson's, there are many times that we see Parkinson's patients, and about a quarter of them don't really respond. There's some features that don't respond to levodopa that may not be so specific, but also can be helpful in this disease. Dr Monteith: And what about the red flags for cortical basilar syndrome? Dr Farland: So, for cortical basilar syndrome, some of the red flags again are this rapidly depressive syndrome tends to be, at least in its classical present presentation, more asymmetric in its presentation of parkinsonism, with features including things like dystonic features, okay? For limb dystonia and apraxias---so, inability to do a learned behavior. One of those red flags is a patient who comes in and says, my hand doesn't work anymore, which is something extremely uncommon that you hear in Parkinson's disease. Most of those patients will present, say, I might have a tremor, but they very rarely will tell you that I can't use my hand. So look out for that sign. Dr Monteith: And let's talk a little bit about some of the advances in the fields you mentioned, evolving biomarker and imaging capacities. So, how are these advances useful in helping us understand these conditions, especially when there's so much heterogeneity? Dr Farland: I might start by talking a little bit about some of the clinical criteria that have advanced. Why don't we start there and just discuss some of the advances? I think in PSP, I think, originally we had both probable and possible diagnoses of PSP, and the diagnostic criteria were basically focused on what was what's called “classical PSP” or “Richardson syndrome”. But now we recognize that there are multiple phenotypes. There's an overlap with Parkinsonism that's slower in progression and morphs into PSP, the classical form. There's a frontal behavioral variant where patients present with that frontal behavioral kind of thing. There's a speech-language variant that can overlap with PSP. So they have prominent speech language, potentially even apraxia speech. So, recognition of these different phenotypes is sort of a new thing in this field. There's even overlap with cortical basal syndrome and PSP, and we note that the pathology can overlap as well. So, I think that's one of the things that have changed over time. And these were- recently came out in 2017 in a new publication in the Movement Disorders Society. So, in terms of diagnostic tests as well---and there's been quite a bit of evolution---really still to date, our best diagnostic test is imaging. MRI is really one of our best tests currently. Currently blood tests, spinal fluid, there's new biomarkers in terms of skin… they're still in the research phase and not necessarily very specific yet. So, we rely heavily on imaging still; and for PSP, what we're looking for largely are changes in the brain stem, and particularly focused on the midbrain. So disproportionate midbrain atrophy compared to the pons and the rest of the midbrain is a fairly specific intensive sign for PSP. Whereas in MSA we see more of a pontine atrophy compared to the midbrain. So that can be really helpful, and there are lots of different new measurements that can be done. PET scans are also being used as well. And there are new PET markers, but they still remain kind of research-based, but are becoming more and more prevalent and may be available soon for potential use. Although there's some overlap with PET tracers with Alzheimer's disease and different Tau isoforms. So, something to be wary about, but we will be seeing some of these soon coming out as well. More kind of up-to-date things include things like the spinal fluid as well as even some of the skin biopsies. And I think we've heard some word of recent studies that have come out that potentially in the very near future we might actually have some Tau protein tests that we can look at Tau either in spinal fluid or even in a skin biopsy. But again, still remains research-based and, we still need more information as to whether these tests can be reproducible and how sensitive or specific they are. Dr Monteith: It sounds like, when really approaching these patients, still, it's a lot of back to the history, back to the clinical and some basic imaging that we should be able to identify to distinguish these types of patients, and we're not quite where we need to be yet for biomarker. Dr Farland: I totally agree with you. I think it starts, really, with the clinical exam and that's our main focus here; and understanding some of the new clinical criteria which are more sensitive, but also specific, too. And they're really useful to look at. So, I think reviewing those; patients do progress, following them over time can be really useful. And then for diagnosis, getting imaging if you suspect a patient has an atypical presentation of parkinsonism, to look for signs or features that might be specific for these different disorders. Dr Monteith: Why don't we take a typical case, a typical patient that you would see in clinic, and walk us through the thought process---especially, maybe they presented somewhat early---and the different treatment approaches to helping the patient, and of course their family. Dr Farland: Yeah, sure. So, a typical patient might be someone who comes in with, like, a three year history of progressive gait problems and falling. And let's say the patient says, I'm falling backwards frequently. They may have had, like, a rib fracture, or they hit their head once, and they're describing some speech issues as well. Now they're relying on a walker and family members saying they rarely let them be by themselves. And there may be some slowing of their cognitive function and maybe a bit of withdrawal. So that's a typical patient. So, the approach here is really, what are some of the red flags? I think already you hear a red flag of a rapidly progressive disease. So, Parkinson's disease patients rarely have frequent falls within the first five years. So, this is within three years or less. You're already hearing early onset of gait problems and falling, and particularly falling backwards rather than forwards as often Parkinson's disease patients do. You're hearing early speech problems and maybe a subtle hint of cognitive slowing and some withdrawal. So, a lot of things that sort of are red flags. So, our approach really would be examining this patient really closely. Okay? We'd be listening to the history, looking at the patient. One thing is that some of these patients come in, they may be in a wheelchair already. That's a red flag for us. If they're wearing sunglasses---sometimes we see that patients, they have photosensitivity and they're in a chair and they're wearing sunglasses---you take the glasses off and you look at their face and they have that sort of a facial stare to them---not just the masked face, but the stare---and their eyes really aren't moving. So, another kind of clue, maybe this is probably something atypical, particularly PSP is what I'm thinking about. So, the approach is really, do a thorough exam. I always recommend looking at eye movements and starting with volitional saccades, not giving them a target necessarily, but asking them to look up and then look down. And then particularly look at the speed of downgaze and whether they actually have full versions down, are able to do that. That's probably your most sensitive test for a patient who has PSP. Not the upgaze, which can be- upgaze impairment in older patients can be nonspecific. So, look for that down gaze. So, if I can get out one message, that's one thing that can be easily done and examined fairly quickly for diagnosis of these patients. And then just look for signs of rigidity, bradykinesia, maybe even some myelopraxia, and then look at their gait carefully so that there's a high suspicion. Again, if there's some atypical features, imaging is really important. So, my next step would be probably getting an MRI to evaluate whether- do they have brain somatrophy or other widespread atrophy or other signs? You need to think about your differential diagnosis for some of these patients as well. So, common things are common; vascular disease, you can't have vascular parkinsonism or even signs of NPH. Both of those can present with progressive gait difficulty and falls. So, the gait may look more like Parkinson's rather than ataxic gait that we see in classic PSP, but still they have early gait issues, and that can be a mimicker of PSP, So looking for both of those things in your imaging. Think about sort of autoimmune potentially causes. So, if they have a really rapid progressive cause, there are some rare autoimmune things. There have been recent reports of things like IgLON5, although there's limited cases, but we're doing more screening for some of those autoimmune causes. And then even some infectious causes like Whipples, that are rarely present like this. Okay? And have other signs and features. Dr Monteith: So, let's say you diagnose this patient with PSP and you're assessing the patients to see how you can improve their quality of life. So, what are some potential symptomatic managements that will help our patient? Dr Farland: I recommend for most all of these patients… while the literature indicates that many patients with PSP, and especially corticobasal syndrome, don't respond well to levodopa. So, the classic treatment for parkinsonism. However, we all recommend a trial of levodopa. These patients may respond partially to doses of levodopa, and we try to push the doses a bit higher. So, the recommended trial is usually a dose up to roughly 1000 milligrams of levodopa per day. And give it some time, at least two, if not actually three months of a trial. If not well-tolerated, you can back off. If there's no response at all or no improvement, then slowly back off and taper patients off and ask them to tell you whether they feel like they're actually worsening. So, many patients, sometimes, don't recognize the improvements, or family members don't recognize it until we actually taper them back off. And they may end up saying there are some other things that even recognize. Even some nonmotor benefits can be seen with levodopa. In some cases, we do keep them on levodopa, but levodopa's our best therapy for this. Dopamine agonists, MAO inhibitors, have all been sort of tried and they've been studied, but often don't really help or fail to help benefit these patients and could be fraught with some other side effects. I think many people do also turn to Amantadine as a treatment for Parkinson's, gait problems, freezing, if you see it in these disorders. Yet Amantadine is fraught with issues of side effects, including cognitive issues, and I think is not well-tolerated. But there are the rare patient who actually does respond to this or claims they respond to this. By and large, these patients relentlessly progress, unfortunately. So, beside treatment of other symptoms, I think it's really important to recognize that they require supportive cares and therapy. So, starting those early on and getting your allied healthcares kind of involved. So that includes people like physical, occupational therapy for the gait issues, the falls, occupational therapy for doing daily activities. Speech language pathology can be really a critical player for these because of the early speech and language issues, as well as swallow difficulties. Swallow is compared quickly in these patients. And so, we do recommend the screening evaluation, then often following patients either every six- or even annually, at least, with a swallow evaluation. And we recommend the fluoroscopic-guided kind of modified barium swallow for these patients.  Dr Monteith: And how does that differ if, let's say, the patient had cortical basilar syndrome? What are some of the symptomatic treatments that would be high on your consideration? Dr Farland: So actually, these patients also have a very similar approach, and they often have some overlapping features. Maybe a little bit of difference in terms of the level of apraxia and some dystonic features that you see in corticobasal syndrome. So, as I mentioned earlier that these patients have a more typ- when they present, typically have a more asymmetric presentation. And one of the biggest issues is this limb apraxia. They may have abnormal movements as well as, like, the alien limb-type phenomena as well. So, the focus of therapy, while similar in the sense we focus on the parkinsonism, I do always try levodopa and try to ramp up the doses to see if it benefits. It does often fail, but it's definitely worth trying. The other focus of these patients is trying to treat symptoms. Dystonia, those features… in some cases, we can help; if it's painful or uncomfortable, muscle relaxants can be used. If it's vocal, things like Botox can be really helpful. Often times it is more palliative than actually restorative in terms of function, but still can be really helpful for patients who ask about pain and discomfort and trying to treat. And then of course, again, the focus on our supportive care. We need to build that network and build that team of folks, the therapists, the physical, occupational, and the speech therapist to help them. If they have language problems---like either in PSP or corticobasal---I'll also include my request to a speech language pathologist to work on cognitive function. That's a special, additional thing you have to ask for and then specifically request when you make a referral to a speech language pathologist. Dr Monteith: That is so important. I think keeping the simulation, keeping the social support, and I would probably guess that you would also include screening for sleep and mood disorder. Dr Farland: Absolutely. Mood disorders are really big in these diseases. Patients are suffering terribly. You do hear about labile mood in both of these diseases, particularly PSP; and even what's called pseudobulbar palsy, where the mood is not always congruent with the affect. So they may laugh or cry inappropriately, and particularly the crying can be very disturbing to family and caregivers to see that. And so, treating those things can be really important. So always asking about the mood issues. Depression in particular is something that we're very sensitive about, and there is a higher incidence of suicidal ideations. Asking about that and feeling and making sure that they are in a safe environment can be really important. Dr Monteith: Thank you so much. Dr Farland: Thank you. Dr Monteith: Today I've been interviewing Dr Nikolaus McFarland about his article on progressive supranuclear palsy and cortical basilar syndrome, which appears in the August 2025 Continuum issue on movement disorders. Be sure to check out Continuum Audio episodes from this and other issues, and thank you to our listeners for joining today. Dr Monteith: This is Dr Teshamae Monteith, Associate Editor of Continuum Audio. If you've enjoyed this episode, you'll love the journal, which is full of in-depth and clinically relevant information important for neurology practitioners. Use the link in the episode notes to learn more and subscribe. AAN members, you can get CME for listening to this interview by completing the evaluation at continpub.com/audioCME. Thank you for listening to Continuum Audio.

From United to win the league to Mbeumo to grow an Afro, Join Joe, Jay, Adam and Stephen Howson for their Hot Takes going into the 25/26 Premier League Season! Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

Send us a textIn this episode of Navigating the Customer Experience, we are joined John McCahan who is a Customer Experience and Service Executive Leader who has transformed CX across industries including automotive, banking, logistics, manufacturing, retail, and most recently at FTD, where he led its post-bankruptcy customer experience transformation. Currently a Board Member of FullCircle and Advisory Board Member for Execs in the Know, John's career spans leadership roles at Avon, Milacron, Fifth Third Bank, Target, and Equifax, as well as eight years of service as a U.S. Army Captain. He was recently named one of the “100 Leaders Transforming Customer Experience.”In this conversation, John shares how his journey into CX began unexpectedly after his military career, when he was asked to lead an underperforming contact center. He discovered his passion for helping people help others and driving organizations to improve execution in service delivery. He emphasizes that customer issues often stem not from frontline staff but from organizational execution failures.Top Competencies for Exceptional Service Delivery John identifies three critical behaviors that cut across all industries:Meet customers where they want to be met—via phone, chat, AI, or digital channels, adapting to customer preferences across demographics and cultures.Leverage frontline insights—agents hear customer issues daily and provide the most accurate view of recurring problems. Fixing root causes reduces unnecessary contacts and strengthens customer trust.Embed CX into company culture—true transformation happens when CX is embraced across the entire organization, not just by service teams.Convincing Leadership of CX Value John shares strategies for professionals struggling to gain executive buy-in: (1) identify and track metrics that matter, (2) ensure CX leaders have a voice where decisions are made, and (3) live customer centricity through action. He highlights loyalty and lifetime value (LTV) as vital measures, citing FTD's success in more than doubling its LTV by shifting from transactional interactions to long-term relationships. He also stresses patience—cultural change takes years, not months, to take hold.Vendor and Partner Alignment John's credo, “Find vendors and partners that fit your business,” underscores his belief that success requires alignment in vision, culture, and technology. He shares examples where misaligned outsourcing relationships caused friction, while true partnerships created collaboration, transparency, and innovation. He draws on military principles such as “Fail fast, fail early, fail small” and occasionally “Ask forgiveness, not permission” to illustrate how decisive leadership can accelerate progress.AI and the Future of CX For John, AI is not about replacing people but enhancing effectiveness. He uses Microsoft Copilot daily and is especially excited about the potential of Agentic AI—intelligent systems that anticipate and personalize experiences. He imagines applications like concerts or restaurants where AI tailors interactions to individual preferences, turning ordinary transactions into memorable moments.Books and Inspirations Two books deeply influenced his leadership: Who Moved My Cheese? by Spencer Johnson, which taught him to embrace change, and Would You Do That to Your Mother? by Jeanne Bliss, which reinforced empathetic, customer-first leadership. He illustrates this philosophy with a powerful story of a loyal 91-year-old customer sending monthly flowers to his wife, showing how empowered, compassionate agents can turn service failures into loyalty-building experiences.Listeners can connect with John on LinkedIn. Follow

Laurie Whitwell is back in the studio for the first time since returning from the US Tour, and its been a busy week for Man United! He gives us the update on how United managed to acquire Benjamin Sesko and how far we would have to stretch to sign Carlos Baleba... join Jay, Joe and Laurie Whitwell for Inside United! Read Laurie's articles here! - https://www.nytimes.com/athletic/author/laurie-whitwell/ Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Chapters: 0:00 - Intro 2:04 - Baleba & Brighton 8:57 - United's Finances 12:12 - Benjamin Sesko 19:26 - Arsenal's Striker Race 23:34 - Affordability 31:01 - Need To Sell? 32:37 - Rasmus Hojlund 39:02 - Zirkzee's Role 42:20 - Alejandro Garnacho 47:52 - 'The Bomb Squad' 52:58 - Goalkeepers Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

We love to hear from our listeners. Send us a message.In Episode 109 of Cell & Gene: The Podcast, Host Erin Harris talks to Will Chou, M.D., CEO of Passage Bio about the promise and challenges of developing gene therapies for frontotemporal dementia (FTD), a neurodegenerative disease with strong genetic underpinnings. Dr. Chou discusses the biological basis of FTD and the complex scientific, manufacturing, and regulatory hurdles that come with targeting the brain. They discuss the latest interim results from the upliFT-D study of Passage Bio's PBFT02, including safety and tolerability findings, dose cohort comparisons, and the evolving strategies around immunosuppression. Dr. Chou also highlights upcoming milestones for PBFT02 and what they could mean for advancing gene therapies in neurodegenerative diseases.Subscribe to the podcast!Apple | Spotify | YouTube Visit my website: Cell & Gene Connect with me on LinkedIn

We kicked off the program with four news stories and different guests on the stories we think you need to know about!Malden Nonprofit Offers Beach Equipment For Those With Disabilities – How one local nonprofit's mission is to help those with disabilities live a fulfilling life.Guest: Rachel Kaprielian – CEO of Triangle, Inc. The race to find a cure for ALS. Activist talks about activism for the genetic ALS and FTD communities, advocates for research funding and healthcare advancements for genetic carriers and people living with ALS. -Also wrote a book: Last Nerve: A Memoir of Illness and the Endurance of Family.Guest: Mindy Uhrlaub - ALS activist and author - founding member of End the Legacy, a nonprofit organization that works to support the genetic ALS and FTD The Matt Brown Foundation Team Running in the 2025 Falmouth Road Race!Guest: Matt Brown – of the Matt Brown Foundation LPGA coming to TPC in Norton! Tournament will bring the world's top LPGA golfers to the region over Labor Day weekend. With a $4.1 million purse, the largest outside the majors and Tour Championship.Guest: Patrick Healey - FM Championship Tournament Director

Katie Prentiss is a mother of four, a former professional photographer, and a current filmmaker. When her mother was diagnosed with frontotemporal dementia (FTD), Katie stepped into the role of primary caregiver, balancing her family, business, and her mom's care. This life-changing experience opened her eyes to the preciousness of life, motivating her to make a bold midlife career pivot into acting and producing. In this episode, Katie shares details about her latest full-length feature film, which she describes as a heartfelt love letter to family caregivers. She shares about how caregiving shaped her personal and professional journey, and how she found acceptance, growth, and healing through what she calls the law of contraction and expansion. Tune in to discover how this powerful concept can help caregivers navigate every stage of the caregiving journey with resilience, purpose, and moxie. Show notes with product and resource links: https://bit.ly/HHCPod211 Receive the podcast in your email here: http://bit.ly/2G4qvBv Order a copy of Elizabeth's book Just for You: a Daily Self Care Journal: http://bit.ly/HHCjournal For podcast sponsorship opportunities contact Elizabeth: https://happyhealthycaregiver.com/contact-us/ The Happy Healthy Caregiver podcast is part of the Whole Care Network. Rate and Review the podcast: https://bit.ly/HHCPODREVIEW

Check out Betfred for latest odds on Manchester United: https://btf.red/inETgvBw/ From exciting new signings to improved play on the pitch, things are looking up for Ruben Amorim's Reds this pre-season - but how have things seemingly improved so much? Join Stephen Howson, Adam McKola, Jay Motty and Joe Smith for Off The Bar! Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

Adam McKola got chance to sit down with the greatest Premier League Centre Back ever! Join us for an exclusive interview with former Manchester United Captain Rio Ferdinand! Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Chapters: 0:00 - Intro 1:32 - Joining Manchester United 4:16 - Paul Ince 6:10 - Not Winning The FA Cup 7:21 - Missing The Drugs Test 12:23 - Relationship With Sir Alex 15:46 - Meeting With Peter Kenyon 19:14 - Anger From The Fans 21:09 - Winning The Champions League 23:57 - Rio's Last Season At United 27:37 - Nemanja Vidic 28:26 - Most Proud Moment 29:21 - Regrets? Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

Inside United is BACK and in the USA! Can Manchester United sign Ollie Watkins and would he work in Amorim's future squad?! Join Joe, Jay and Laurie Whitwell for Inside United! Read Laurie's articles here! - https://www.nytimes.com/athletic/author/laurie-whitwell/ Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Chapters: 0:00 - Intro 1:37 - Mood In Pre-Season 7:04 - Mason Mount 14:04 - Rasmus Hojlund 21:07 - Marcus Rashford 28:03 - Benjamin Sesko 34:09 - Ollie Watkins 39:38 - Midfield Dilemma 43:36 - Bryan Mbeumo Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

Go to https://surfshark.com/paddock or use code PADDOCK at checkout to get 4 extra months of Surfshark VPN! United are looking at their next steps in the transfer market and it's a very important decision to make. Should we look at signing a new striker, midfielder or goalkeeper!? Join Joe, Ronaldo Brown & Jay for The Paddock Podcast LIVE! Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

Carl Anka is back to discuss United's possible next targets in the transfer window following on from a recent article targeting midfielders! Chaos erupts as an Mbeumo breakthrough takes place LIVE in the studio! Join Jay, Joe and Carl Anka for an exclusive interview! Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Chapters: 0:00 - Intro 2:03 - Midfielders 4:28 - Formation 9:58 - Baleba and Brighton 26:26 - Raising Funds 35:38 - Hackney and Wharton 46:46 - Mainoo Comparison 53:34 - Mbeumo Live Bid News 1:05:02 - Back Three 1:13:22 - Nicolas Jackson 1:15:53 - Ollie Watkins Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

Another Transfer Window that Ruben Amorim is not being backed in?! Should INEOS and Sir Jim Ratcliffe do better?! Join Joe, Ronaldo Brown & Jay for The Paddock Podcast LIVE! Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

Stephen Howson, Jay Motty, Adam McKola. Oasis. The Brew. Nothing More! Join us for a special edition of The Brew LIVE! Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

Go to https://surfshark.com/paddock or use code PADDOCK at checkout to get 4 extra months of Surfshark VPN! Manchester United are running out of options for a Striker this summer, with Gyokeres joining Arsenal and Victor Osimhen close to signing with Galatasaray, who is left for the Reds?! Join Joe, Jay and Ronaldo for the Paddock Podcast LIVE! Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Chapters: 0:00 - Intro 4:01 - Gyokeres to Arsenal 8:31 - United Issues 13:45 - Restructuring The Club 20:26 - Anthony Elanga 25:51 - Victor Osimhen 30:50 - Journeyman Striker? 33:05 - Proven No 9's 39:00 - Osimhen Asking Price 43:33 - Wally of the Week Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

In this special episode, Gresham Harkless reflects on the unexpected difficulty of gaining traction and closing his first sale. Despite consistent effort and staying committed, he admits that the process has been tougher and slower than anticipated.   He shares his experience with a promising candidate who has likely ghosted him, an example of the hesitation he's noticing more frequently in today's uncertain economic climate.   Gresham acknowledges that while the market plays a role, it's on him to adapt and adjust rather than make excuses.   He highlights the importance of focusing more on sales, reducing operational distractions, and leaning into higher-performing lead sources like FTD.   Gresham is recalibrating his approach with a mindset of resilience, experimentation, and self-awareness, looking for focused, strategic shifts that will help him turn persistence into progress.   Blue Star Franchise: http://bluestarfranchise.com Browse the Franchise Inventory: https://bluestarfranchise.com/franchise Is franchising right for you? Check this out to see: http://bluestarfranchise.com/assessment Franchise CEO (A CBNation Site - coming soon) - http://franchiseceo.co Check out our CEO Hack Buzz Newsletter–our premium newsletter with hacks and nuggets to level up your organization. Sign up HERE.  I AM CEO Handbook Volume 3 is HERE and it's FREE. Get your copy here: http://cbnation.co/iamceo3. Get the 100+ things that you can learn from 1600 business podcasts we recorded. Hear Gresh's story, learn the 16 business pillars from the podcast, find out about CBNation Architects and why you might be one and so much more. Did we mention it was FREE? Download it today!

Multiple players since arriving back at Carrington have declared that they wish to leave Manchester United! Join us for a special Independence Day edition of The Brew with Jay, Joe and Stephen Howson An evening with Andy Cole: https://www.designmynight.com/manchester/event-space/grosvenor-casino-didsbury/an-evening-with-andy-cole Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

There are plenty of possible combinations for how United will line-up next season from the goalkeeper to centre forward. With a blank Starting XI, and a list of current and potential United players, join Adam McKola, Jay and Joe for Off The Bar! Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Chapters: Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

Former NFL Linebacker Will Compton presents a Bussin’ With The Boys production, For The Dads! As a father of two, Will knows how hard the job of a dad can be. Thus he created a safe space for dads to come together and talk about the insane stuff that we see and deal with every day. He is joined by Sherman Young, whose first born is just days away, so Will share the highs and lows of having your first child. Sherm, understandably nervous and anxious to start his journey into fatherhood, confides in Will his excitement and trepidations for the arrival of his daughter, Scarlett. Will starts out by throwing around names for the For The Dads community. Then Sherm talks to Will about his worries regarding getting enough sleep once Scarlett is born. Plus, Will talks Sherm through delivery room do's and don’ts and Sherm gets emotional talking about the pending arrival of his daughter. The boys take a call from a disappointed Husker Girl Dad, and Will devises a plan to help his daughter understand jerseys aren’t just for boys. For the message of the week, Will delivers a "letter to Sherm" welcoming him into “The Fatherhood.” We hope you enjoy! Let us know in the comments what you'd like to see more of. Check out the merch at BWTB.com! ..and as always BIG HUGS and TINY KISSES! TIMELINE CHAPTERS 00:00 - Intro 06:52 - Will throws around some FTD community names 10:23- Sherm talks about nerves for being a father 16:07 - Sherm is nervous about lack of sleep / Dad Losses 28:56 - Crack A Cold One 39:11 - What Are The Odds? 43:42 - Survival Kit 52:06 - Dad Hacks 1:02:36 - Call-Ins 1:36:59 - Will's message to Sherm ----- For The Dads is for every guy who needs a place to talk, vent, and laugh about all the insane, hilarious, and chaotic sh** (sometimes literal) that comes with being a dad. Hosted by Will Compton–NFL Vet, creator of Bussin' With the Boys, and proud dad of two. This show isn’t about expert advice and how fatherhood is the greatest thing on earth—it’s about embracing the love and suck of parenthood every day. From balancing work and family to battling the mental load, fears, and the moments that wreck you in the best way, we dive into it all with honesty, vulnerability, and a sense of humor. Cause at the end of the day... us dads have no idea what we're doing. Alongside Will is his producer Sherman Young, a soon-to-be dad who’s currently enjoying his last few months of uninterrupted sleep and freedom. Together, they’ll break down everything that can go right and wrong (...usually wrong) when you bring tiny humans into this world. Expect funny parenting stories, laughs, call-ins, advice, weekly themes, and the kind of conversations you’d have over a cold beer in the garage. Whether you’re raising teens or still Googling “how to install a car seat,” For the Dads is the ultimate podcast for dads who are in it, about to be in it, or just trying to do their best while screwing it up along the way. ----- FOLLOW THE BOYS Instagram: / bussinwtb Twitter: / bussinwtb Facebook: / bussinwtb LISTEN iTunes: http://bit.ly/BWTB_Apple Spotify: http://bit.ly/BWTB_Spotify ----- SUPPORT OUR SPONSORSSee omnystudio.com/listener for privacy information.

Manchester football reporter Mark Critchley is back to break down United's finances amidst an important transfer window, answering the questions surrounding PSR, selling assets and footballing business loopholes! Join Jay and Joe for an exclusive interview... Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Chapters: 0:00 - Intro 5:35 - Finances 8:30 - Outgoings 13:13 - How Clubs Deal With PSR 19:36 - Transfer Trend Shift 25:20 - Garnacho 29:37 - Dressing Room Culture 34:24 - Mbeumo Update 40:00 - Other Deals? 42:27 - Football Business Loopholes 48:22 - United Next Signings 49:34 - Striker Situation Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

In our Season 10 finale, Alyssa describes the FTD journey with her father, Tommy - starting from her perspective at 11 years-old. She weaves us through her memories of her father's strange behavior - and the long road to finding answers. This story covers so much about family dynamics - but also what a healing journey can look like. And the unbelievable things that happen in life that we just can't explain. Thank you, Alyssa for sharing your story with us. You are an incredible woman. Keep fighting.----------A VERY SPECIAL THANK YOU TO TODAY'S SPONSORS:⁠⁠PROGRANULIN INFORMATION NAVIGATOR⁠⁠ &⁠⁠AVIADOBIO⁠⁠⁠⁠⁠. Mentioned in this episode: Season 9, Episode 15: Grief & Genetic Testing which you can listen to ⁠⁠here⁠⁠.Gonna miss us on the break? Support our podcast and join us on ⁠⁠⁠⁠⁠Patreon⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ - You get exclusive content + a space to share and connect with others. ⁠⁠⁠⁠⁠⁠⁠⁠⁠www.patreon.com/remembermecommunity⁠⁠⁠⁠⁠⁠⁠⁠⁠ If you're curious about anything RM, we'd love to connect with you on ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram, and visit ⁠⁠⁠⁠⁠⁠⁠⁠our website at⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ www.remembermeftd.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, all the latest updates! ------Remember Me Podcast + Community is here to offer hope + human connection for families, caregivers, and individuals impacted by Frontotemporal Dementia (FTD). Always, always accept the good.

It's tier list time again... this time we're looking at a few free agents currently on the market. Lionel Messi, anyone? Join Joe, Jay and Ronaldo for The Paddock Podcast LIVE! Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

Check out Manual's at home testosterone testing: https://www.manual.co/testosterone-replacement-therapy/initial-testosterone-blood-test?coupon=PADDOCK45&utm_source=youtube&utm_medium=influencer&utm_campaign=stretfordpaddock United have a lot to do to get back to their former glory, and with teams like Liverpool and Man City going from strength to strength in the transfer window, how long will it take us to get back challenging for the Premier League? Join Stephen Howson, Jay and Joe for Off The Bar! Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Chapters: 0:00 - Intro 1:09 - Cunha and Mbeumo 2:38 - Premier League 24/25 12:03 - Villa and Newcastle 23:27 - Bruno Fernandes 26:04 - Liverpool 31:18 - Project 150 35:10 - Man City 46:25 - Reminicing Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

We're in that time of the year where the season is over, pre-season tour is a few weeks away and we have no Man United to watch. What else is there to possibly do? Join all 4 of our hosts, Jay, Ste Howson, Joe and Adam McKola for the Brew LIVE! Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

Go to https://surfshark.com/paddock or use code PADDOCK at checkout to get 4 extra months of Surfshark VPN! Recent social media posts and replies have once again brought up the debate surrounding Manchester United's Culture! Join Joe, Ronaldo and Fin [Academy Scoop] for The Paddock Podcast LIVE! Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Chapters - 0:00 - Intro 3:46 - Culture Switch 9:50 - Culture When Winning 12:48 - Garnacho Social Post 19:24 - Amorim Coaching Style 24:30 - Strength of Character 28:40 - Recruitment 30:50 - Signings Under Ineos 41:25 - Harry Maguire Redemption 43:59 - Wally of the Week Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

Join all 4 of our hosts, Jay, Ste Howson, Joe and Adam McKola for the Brew LIVE! Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Chapters: 0:00 - Intro 1:35 - US Tour 5:58 - United Mount Rushmore 21:48 - Favourite Chant 27:30 - USA Plans 35:58 - Best Actor 43:01 - Penalties 45:21 - Dream Movie Roles Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

With plenty of activity elsewhere in the transfer market and United still only to have confirmed Cunha for next season, is the clock ticking to get a few more names at Old Trafford! Join Stephen Howson, Adam McKola, Jay and Joe for this episode of Off The Bar! Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Chapters: 0:00 - Intro 1:03 - Fixtures 9:00 - Liverpool 12:49 - Arsenal 18:42 - United Approach 25:13 - Marcus Rashford 32:08 - Media Pressure 36:44 - Man City 46:07 - Title Winners? Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

Manchester United seemed to have increased their interest in Frankfurt's Hugo Ekitike, but what will it take to get the man in demand to Old Trafford... Join Sky Sports' Dharmesh Sheth and Joe to find out! Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Chapters: 0:00 - Intro 1:45 - Mbeumo 10:18 - Ekitike 17:16 - Gyokeres 20:10 - United Sales 27:20 - Amorim's Plan Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

Journalist Peter Hall joins Jay and Joe for The Brew as they dive into why Sir Dave Brailsford has stepped back from his role at Man United! Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Chapters: 0:00 - Intro 1:50 - Mbeumo to Spurs? 10:59 - Viktor Gyokeres 16:40 - Outs 23:45 - Rashford to Barca? 27:55 - Kobbie Concerns 32:24 - Brailsford Explained 40:35 - Wilcox Autonomy Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

There's been plenty of action in the transfer window so far, including Cunha complete to United, Mbeumo hopefully just around the corner and a huge €150 million move of Florian Wirtz to Liverpool! Jay, Joe and Adam McKola rank each teams business in the window so far for Off The Bar! Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Chapters: 0:00 - Intro 1:33 - United 9:54 - Arsenal 16:33 - Bournemouth 19:17 - Brentford 22:28 - Brighton 25:25 - Chelsea 30:19 - Liverpool 38:03 - City 41:31 - Newcastle 43:31 - Forest 44:58 - Spurs Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

Jackie von Salm, a chemist and Chief Scientific Officer at Psilera, shares her father Terry's journey with FTD. We loved how Jackie was so raw + honest about family dynamics, becoming Terry's POA in her 20s, and how she learned how to be direct + honest in how she felt and what she needed while caregiving. You can learn more about what she's up to at Psilera here. You can also hear us chat all about their Research Summit this year on Patreon - along with an extended version of this episode.Patreon⁠⁠⁠⁠⁠ - join us ⁠⁠⁠⁠⁠www.patreon.com/remembermecommunity⁠⁠⁠⁠⁠ - you get exclusive content and it's a great way to support the show!----------Special thank you to today's sponsor ⁠⁠AVIADOBIO⁠⁠.If you're curious about anything RM, we'd love to connect with you on ⁠⁠⁠⁠⁠⁠⁠⁠Instagram, and visit ⁠⁠⁠⁠⁠our website at⁠⁠⁠⁠⁠⁠⁠⁠ www.remembermeftd.com⁠⁠⁠⁠⁠⁠⁠⁠, all the latest updates! ------Remember Me Podcast + Community is here to offer hope + human connection for families, caregivers, and individuals impacted by Frontotemporal Dementia (FTD). Always, always accept the good.

Go to https://surfshark.com/paddock or use code PADDOCK at checkout to get 4 extra months of Surfshark VPN! Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Chapters: 0:00 - Intro 4:41 - Goalkeepers 12:14 - Defenders 26:40 - Midfielders 42:51 - Forwards 47:53 - Wally of the Week Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

Join us for an exclusive interview with The Athletic's Carl Anka! Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

After some strong words from United legend, David Beckham, this week - join Joe, Jay and Fin for the Paddock Podcast LIVE as they discuss some fundamental changes at the club! Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

When someone we know or love starts to develop psychological issues, we don't often associate it with a form of dementia. However, this trait is one of the most common signs of frontotemporal dementia (FTD) — the most common neurodegenerative disease in people under the age of 65. In his new book, Mysteries of the Social Brain: Understanding Human Behavior Through Science, Dr. Bruce Miller highlights his experiences observing people with FTD and what they have taught him about what he calls the "social brain."Dr. Bruce Miller has been observing people with FTD for decades in the Memory and Aging Center at the University of San Francisco, where he is also Professor of Neurology and the Founding Director of the Global Brain Health Institute. He shares key insights on how to keep our "social brain" healthy and how it can even unlock our creative potential.

Technical difficulties may have stopped this one being live, but that wasn't preventing the lads from steering off topic. Stephen Howson and Jay Motty are joined by comedian Kae Kurd to talk conspiracy theories and more on this week's episode of The Brew! Become a member! - https://www.youtube.com/channel/UC7w8GnTF2Sp3wldDMtCCtVw/join Stretford Paddock has content out EVERY DAY, make sure you're subscribed for your Man United fix! - https://bit.ly/DEVILSsub

My HoneyDew this week is comedian Kelsey Cook! Check out her latest special, Mark Your Territory, now available on YouTube and Hulu, and her podcast, Pretend Problems, co-hosted with comedian Chad Daniels. Kelsey joins me in the studio this week to highlight the lowlight of her mother's battle with frontotemporal dementia (FTD). We dive into the emotional and financial rollercoaster of caregiving, and how genetic testing plays a role in shaping future plans. Plus, Kelsey shares what it's like trying to land jokes in the world's saddest room. SUBSCRIBE TO MY YOUTUBE and watch full episodes of The Dew every toozdee! https://youtube.com/@rsickler SUBSCRIBE TO MY PATREON - The HoneyDew with Y'all, where I Highlight the Lowlights with Y'all! Get audio and video of The HoneyDew a day early, ad-free at no additional cost! It's only $5/month! AND we just added a second tier. For a total of $8/month, you get everything from the first tier, PLUS The Wayback a day early, ad-free AND censor free AND extra bonus content you won't see anywhere else! https://www.patreon.com/TheHoneyDew What's your story?? Submit at honeydewpodcast@gmail.com Get Your HoneyDew Gear Today! https://shop.ryansickler.com/ Ringtones Are Available Now! https://www.apple.com/itunes/ http://ryansickler.com/ https://thehoneydewpodcast.com/ SUBSCRIBE TO THE CRABFEAST PODCAST https://podcasts.apple.com/us/podcast/the-crabfeast-with-ryan-sickler-and-jay-larson/id1452403187 SPONSORS: GhostBed -Head to https://www.GhostBed.com/honeydew and use code HONEYDEW to get an extra 10% off your entire order Cure Hydration -Get 20% off your first order! Stay hydrated and feel your best by visiting https://www.curehydration.com/HONEYDEW and using promo code HONEYDEW