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The double helix structure of DNA was the discovery of the century. However, the story about the discovery is mired in controversy as one of the major contributors, Rosalind Franklin, was conspicuously absent from acknowledgements and died (and subsequently not named) before the Nobel Prize was awarded. In 1968, James Watson wrote the book ‘The Double Helix: A Personal Account of the Discovery of the Structure of DNA' and reads more like a fictional detective novel than an autobiographical account with the portrayal of Franklin as a forceful, gruff and confrontational. Recently, an article in Nature shows an unpublished news article from 1953 (at the time of the discovery) that Franklin's contribution was crucial to uncovering the structure of DNA. Today, we talk to one of the authors of the article in Nature, Nathaniel Comfort, who is Professor of the History of Medicine at John Hopkins University. Link to the article: https://www.nature.com/articles/d41586-023-01313-5 Our special guest is Professor Nathaniel Comfort from the John Hopkins University. His interest lies in the histories of genetics, eugenics, genomics and biomedicine. He has authored two books (The Tangled Field and The Science of Human Perfection), written for Nature, The Atlantic, The Nature as well as appeared on PBS, National Public Radio and the BBC. This is the story of the DNA double helix.See omnystudio.com/listener for privacy information.
James Watson and Francis Crick, who detailed the double-helix structure of DNA in 1953, are perhaps two of the most iconic scientists of the 20th Century. Yet the story of how they made their incredible discovery is perhaps equally famous, with a notorious narrative suggesting that they only identified the structure after taking the work of Rosalind Franklin and using it without her permission. Now, 70 years after the discovery of DNA's structure, it is perhaps time to rewrite the tale. New evidence has now been unearthed, in the form of an overlooked news article and an unpublished letter, that shows that Franklin was truly an equal contributor to the discovery, and Watson and Crick were not as malicious as previously assumed. Together with Matthew Cobb of the University of Manchester, Nathaniel Comfort from Johns Hopkins University, and Angela Creager of Princeton University, Gaia Vince discusses this tantalising tale and finds out more about how this discovery could bring a whole new twist to the story of DNA. Presenter: Gaia Vince Producer: Harrison Lewis Assistant Producer: Jonathan Blackwell
In this podcast discussion we peek into the world projected by J.D. Lasica in his new genetics thriller novel, Biohack. We consider and debate a few ethical issues that arise in the book focusing on the potential implications CRISPR has for our future.J. D. Lasica is an author, Silicon Valley entrepreneur and public speaker. He spoke at the United Nations in 2012 about how to use social media to combat global poverty, and he has given talks on four continents. His new book Biohack is a high-tech genetics thriller.Dr. Katie Hasson, is the Program Director on Genetic Justice at the Center for Genetics and Society. She was an assistant professor of sociology and gender studies at the University of Southern California. She has researched and written on reproductive technologies and women’s health.On This Episode We Discuss:The genetics thriller novel Biohack and the bioethical issues it raisesPotential scientific advances with CRISPR technologyThe bioethical implications of those advancementsWhich countries these advances are most likely to occurThe bioethical debate change between PGD embryo selection and CRISPR edited embryo, prior to in vitro fertilizationPotential restrictions on which genes can be manipulated, disease related vs physical traitsWant to delve further into the bioethics of CRISPR? Check out this article from guest Dr. Katie Hasson about designer DNA not being just for designer babies. Another interesting article that complements our discussion in the podcast is Nathaniel Comfort’s “Can We Cure Genetic Diseases Without Slipping Into Eugenics?” Intrigued by our conversation about a child having three biological parents (this is not science fiction) Leah Lowthrop wrote articles about the impact in the fertility industry and the slippery slope this technique could become. Genetics and Society has many more articles to explore!If you are one of the first ten people to sign up for JD’s J.D.’s Best of Indie email list you will receive a free copy of the “Biohack” ebook plus the Hacked Celebrity Files, a full-color PDF outlining Hollywood celebrities and historical figures targeted by the biotech company in the novel. Can’t wait to see if you have won? Buy the book on Amazon for $1 or read it for free through amazon Kindle Unlimited.Be sure to give both J.D. Lasica and Genetics and Society a follow on Twitter.Stay tuned for the next new episode of DNA Today on July 6th, 2018. New episodes are released on the first and third Fridays of the month. See what else I am up to on Twitter, Instagram, Facebook and iTunes. Questions/inquiries can be sent to info@DNApodcast.com.
Barbara McClintock’s work on the genetics of corn won her a Nobel prize in 1983. Her research on jumping genes challenged the over-simplified picture of chromosomes and DNA that Watson and Crick’s discovery has all too often been used to support. During the half century that she worked at the Cold Spring Harbor Laboratory she became something of a living legend, a pioneer in a time when women weren’t expected to take much interest in science. In that story, she made a profound discovery that her male colleagues dismissed for years, leaving her out in the cold until they finally realized that it was true and granted her a belated Nobel Prize. Philip Ball tells the story of Barbara McLintock's life and work, from her early preference for sports, for solitude, and for intellectual life, that disturbed her parents, to her meticulous research on corn. In conversation with her recent biographer, Dr Nathaniel Comfort of Johns Hopkins University, he explores the facts and the fictions that grew up around her. Philip Ball talks about the legacy of her discovery of jumping genes with Professor Greg Hannon of the Cancer Research UK Institute at Cambridge University, who spent 25 years working in the McLintock Laboratory at Cold Spring Harbor. Picture Corn Cobs, Credit: Philippe Huguen/AFP/GettyImages)
March 17, 2016. Nathaniel Comfort convenes four distinguished scientists on-stage for a live oral history interview about the origins of the RNA world, the world at the dawn of life, before DNA, arising nearly four billion years ago. For transcript, captions, and more information, visit http://www.loc.gov/today/cyberlc/feature_wdesc.php?rec=7353
Released: 28 July 2016 Duration: 43 minutes, 45 seconds James Garrison speaks with latest holder of the Library of Congress Baruch Blumberg chair of astrobiology, Nathaniel Comfort. His current book project is the biography of DNA. Links: Mike Russell New Study Outlines "Water World" Theory of the Origin of Life Cold Spring Harbor Laboratory Dr. Barbara McClintock Steven Benner Credits: Host: James Garrison Producer: Paul Carr Announcer: Erin Carr Music: DJ Spooky and Frank Dorritke
Zack and Nathaniel Comfort, professor of history at Johns Hopkins and NASA/Library of Congress chair in astrobiology, talk about genetics, eugenics, and present-day medicine.
Guest: Comfort, Nathaniel, PhD, Author, Professor, History of Science, Technology and Medicine, Johns Hopkins University Bio and Contact Info Listen (4:20) Debate about race and genetics is really about social justice
“This is a history of promises.”So begins Nathaniel Comfort‘s gripping and beautifully written new book on the relationships between and entanglements of medical genetic and eugenics in the history of the twentieth century. Based on a rich documentary and oral history archive, The Science of Human Perfection: How Genes Became the Heart of American Medicine (Yale University Press, 2012) reframes the histories of early and contemporary human genetics. Rather than treating eugenics as “a contaminant of good, honest biomedicine,” the book shows that early human genetics had many of the same basic goals – human improvement and the relief of suffering – as genetic medicine today. At the same time, contemporary genetic medicine emerges as much less benign than it has often been depicted. All of this is accomplished through a sensitive historical tracing of two major approaches to understanding human heredity through the twentieth century: a Galtonian approach characterized by a concern with quantification, public health, and populations; and a Garrodian approach characterized by an interest in conceptualizing the human as individual, and in synthesizing heredity with other forms of knowledge. As we follow these threads along with Comfort, he introduces us to a bookful of colorful, vibrant characters from the history of medical genetics: the idealistic inventor of a “Gumption Reviver,” the sanitarium-operator who was fond of prescribing yogurt-enemas, and the medical geneticist with a talent for boogie-woogie piano, among others. These figures are embedded in an exceptionally carefully-wrought narrative of the spaces, practices, and events by which medicine became genetic, genetics became molecular, and molecules made the engineering of humanity possible in a new way. In the course of our discussion, we talked about the importance, for Comfort, of paying careful attention to elements of the writer's craft when composing a historical work. The John McPhee essay on narrative structure that was mentioned in that part of the interview can be found here (A subscription to the New Yorker is required to read the full piece.) The Oral History of Human Genetics Project can be found here. Learn more about your ad choices. Visit megaphone.fm/adchoices
“This is a history of promises.”So begins Nathaniel Comfort‘s gripping and beautifully written new book on the relationships between and entanglements of medical genetic and eugenics in the history of the twentieth century. Based on a rich documentary and oral history archive, The Science of Human Perfection: How Genes Became the Heart of American Medicine (Yale University Press, 2012) reframes the histories of early and contemporary human genetics. Rather than treating eugenics as “a contaminant of good, honest biomedicine,” the book shows that early human genetics had many of the same basic goals – human improvement and the relief of suffering – as genetic medicine today. At the same time, contemporary genetic medicine emerges as much less benign than it has often been depicted. All of this is accomplished through a sensitive historical tracing of two major approaches to understanding human heredity through the twentieth century: a Galtonian approach characterized by a concern with quantification, public health, and populations; and a Garrodian approach characterized by an interest in conceptualizing the human as individual, and in synthesizing heredity with other forms of knowledge. As we follow these threads along with Comfort, he introduces us to a bookful of colorful, vibrant characters from the history of medical genetics: the idealistic inventor of a “Gumption Reviver,” the sanitarium-operator who was fond of prescribing yogurt-enemas, and the medical geneticist with a talent for boogie-woogie piano, among others. These figures are embedded in an exceptionally carefully-wrought narrative of the spaces, practices, and events by which medicine became genetic, genetics became molecular, and molecules made the engineering of humanity possible in a new way. In the course of our discussion, we talked about the importance, for Comfort, of paying careful attention to elements of the writer's craft when composing a historical work. The John McPhee essay on narrative structure that was mentioned in that part of the interview can be found here (A subscription to the New Yorker is required to read the full piece.) The Oral History of Human Genetics Project can be found here. Learn more about your ad choices. Visit megaphone.fm/adchoices
“This is a history of promises.”So begins Nathaniel Comfort‘s gripping and beautifully written new book on the relationships between and entanglements of medical genetic and eugenics in the history of the twentieth century. Based on a rich documentary and oral history archive, The Science of Human Perfection: How Genes Became the Heart of American Medicine (Yale University Press, 2012) reframes the histories of early and contemporary human genetics. Rather than treating eugenics as “a contaminant of good, honest biomedicine,” the book shows that early human genetics had many of the same basic goals – human improvement and the relief of suffering – as genetic medicine today. At the same time, contemporary genetic medicine emerges as much less benign than it has often been depicted. All of this is accomplished through a sensitive historical tracing of two major approaches to understanding human heredity through the twentieth century: a Galtonian approach characterized by a concern with quantification, public health, and populations; and a Garrodian approach characterized by an interest in conceptualizing the human as individual, and in synthesizing heredity with other forms of knowledge. As we follow these threads along with Comfort, he introduces us to a bookful of colorful, vibrant characters from the history of medical genetics: the idealistic inventor of a “Gumption Reviver,” the sanitarium-operator who was fond of prescribing yogurt-enemas, and the medical geneticist with a talent for boogie-woogie piano, among others. These figures are embedded in an exceptionally carefully-wrought narrative of the spaces, practices, and events by which medicine became genetic, genetics became molecular, and molecules made the engineering of humanity possible in a new way. In the course of our discussion, we talked about the importance, for Comfort, of paying careful attention to elements of the writer's craft when composing a historical work. The John McPhee essay on narrative structure that was mentioned in that part of the interview can be found here (A subscription to the New Yorker is required to read the full piece.) The Oral History of Human Genetics Project can be found here. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine
“This is a history of promises.”So begins Nathaniel Comfort‘s gripping and beautifully written new book on the relationships between and entanglements of medical genetic and eugenics in the history of the twentieth century. Based on a rich documentary and oral history archive, The Science of Human Perfection: How Genes Became the Heart of American Medicine (Yale University Press, 2012) reframes the histories of early and contemporary human genetics. Rather than treating eugenics as “a contaminant of good, honest biomedicine,” the book shows that early human genetics had many of the same basic goals – human improvement and the relief of suffering – as genetic medicine today. At the same time, contemporary genetic medicine emerges as much less benign than it has often been depicted. All of this is accomplished through a sensitive historical tracing of two major approaches to understanding human heredity through the twentieth century: a Galtonian approach characterized by a concern with quantification, public health, and populations; and a Garrodian approach characterized by an interest in conceptualizing the human as individual, and in synthesizing heredity with other forms of knowledge. As we follow these threads along with Comfort, he introduces us to a bookful of colorful, vibrant characters from the history of medical genetics: the idealistic inventor of a “Gumption Reviver,” the sanitarium-operator who was fond of prescribing yogurt-enemas, and the medical geneticist with a talent for boogie-woogie piano, among others. These figures are embedded in an exceptionally carefully-wrought narrative of the spaces, practices, and events by which medicine became genetic, genetics became molecular, and molecules made the engineering of humanity possible in a new way. In the course of our discussion, we talked about the importance, for Comfort, of paying careful attention to elements of the writer’s craft when composing a historical work. The John McPhee essay on narrative structure that was mentioned in that part of the interview can be found here (A subscription to the New Yorker is required to read the full piece.) The Oral History of Human Genetics Project can be found here. Learn more about your ad choices. Visit megaphone.fm/adchoices
“This is a history of promises.”So begins Nathaniel Comfort‘s gripping and beautifully written new book on the relationships between and entanglements of medical genetic and eugenics in the history of the twentieth century. Based on a rich documentary and oral history archive, The Science of Human Perfection: How Genes Became the Heart... Learn more about your ad choices. Visit megaphone.fm/adchoices
“This is a history of promises.”So begins Nathaniel Comfort‘s gripping and beautifully written new book on the relationships between and entanglements of medical genetic and eugenics in the history of the twentieth century. Based on a rich documentary and oral history archive, The Science of Human Perfection: How Genes Became the Heart of American Medicine (Yale University Press, 2012) reframes the histories of early and contemporary human genetics. Rather than treating eugenics as “a contaminant of good, honest biomedicine,” the book shows that early human genetics had many of the same basic goals – human improvement and the relief of suffering – as genetic medicine today. At the same time, contemporary genetic medicine emerges as much less benign than it has often been depicted. All of this is accomplished through a sensitive historical tracing of two major approaches to understanding human heredity through the twentieth century: a Galtonian approach characterized by a concern with quantification, public health, and populations; and a Garrodian approach characterized by an interest in conceptualizing the human as individual, and in synthesizing heredity with other forms of knowledge. As we follow these threads along with Comfort, he introduces us to a bookful of colorful, vibrant characters from the history of medical genetics: the idealistic inventor of a “Gumption Reviver,” the sanitarium-operator who was fond of prescribing yogurt-enemas, and the medical geneticist with a talent for boogie-woogie piano, among others. These figures are embedded in an exceptionally carefully-wrought narrative of the spaces, practices, and events by which medicine became genetic, genetics became molecular, and molecules made the engineering of humanity possible in a new way. In the course of our discussion, we talked about the importance, for Comfort, of paying careful attention to elements of the writer’s craft when composing a historical work. The John McPhee essay on narrative structure that was mentioned in that part of the interview can be found here (A subscription to the New Yorker is required to read the full piece.) The Oral History of Human Genetics Project can be found here. Learn more about your ad choices. Visit megaphone.fm/adchoices
“This is a history of promises.”So begins Nathaniel Comfort‘s gripping and beautifully written new book on the relationships between and entanglements of medical genetic and eugenics in the history of the twentieth century. Based on a rich documentary and oral history archive, The Science of Human Perfection: How Genes Became the Heart of American Medicine (Yale University Press, 2012) reframes the histories of early and contemporary human genetics. Rather than treating eugenics as “a contaminant of good, honest biomedicine,” the book shows that early human genetics had many of the same basic goals – human improvement and the relief of suffering – as genetic medicine today. At the same time, contemporary genetic medicine emerges as much less benign than it has often been depicted. All of this is accomplished through a sensitive historical tracing of two major approaches to understanding human heredity through the twentieth century: a Galtonian approach characterized by a concern with quantification, public health, and populations; and a Garrodian approach characterized by an interest in conceptualizing the human as individual, and in synthesizing heredity with other forms of knowledge. As we follow these threads along with Comfort, he introduces us to a bookful of colorful, vibrant characters from the history of medical genetics: the idealistic inventor of a “Gumption Reviver,” the sanitarium-operator who was fond of prescribing yogurt-enemas, and the medical geneticist with a talent for boogie-woogie piano, among others. These figures are embedded in an exceptionally carefully-wrought narrative of the spaces, practices, and events by which medicine became genetic, genetics became molecular, and molecules made the engineering of humanity possible in a new way. In the course of our discussion, we talked about the importance, for Comfort, of paying careful attention to elements of the writer’s craft when composing a historical work. The John McPhee essay on narrative structure that was mentioned in that part of the interview can be found here (A subscription to the New Yorker is required to read the full piece.) The Oral History of Human Genetics Project can be found here. Learn more about your ad choices. Visit megaphone.fm/adchoices
“This is a history of promises.”So begins Nathaniel Comfort‘s gripping and beautifully written new book on the relationships between and entanglements of medical genetic and eugenics in the history of the twentieth century. Based on a rich documentary and oral history archive, The Science of Human Perfection: How Genes Became the Heart of American Medicine (Yale University Press, 2012) reframes the histories of early and contemporary human genetics. Rather than treating eugenics as “a contaminant of good, honest biomedicine,” the book shows that early human genetics had many of the same basic goals – human improvement and the relief of suffering – as genetic medicine today. At the same time, contemporary genetic medicine emerges as much less benign than it has often been depicted. All of this is accomplished through a sensitive historical tracing of two major approaches to understanding human heredity through the twentieth century: a Galtonian approach characterized by a concern with quantification, public health, and populations; and a Garrodian approach characterized by an interest in conceptualizing the human as individual, and in synthesizing heredity with other forms of knowledge. As we follow these threads along with Comfort, he introduces us to a bookful of colorful, vibrant characters from the history of medical genetics: the idealistic inventor of a “Gumption Reviver,” the sanitarium-operator who was fond of prescribing yogurt-enemas, and the medical geneticist with a talent for boogie-woogie piano, among others. These figures are embedded in an exceptionally carefully-wrought narrative of the spaces, practices, and events by which medicine became genetic, genetics became molecular, and molecules made the engineering of humanity possible in a new way. In the course of our discussion, we talked about the importance, for Comfort, of paying careful attention to elements of the writer’s craft when composing a historical work. The John McPhee essay on narrative structure that was mentioned in that part of the interview can be found here (A subscription to the New Yorker is required to read the full piece.) The Oral History of Human Genetics Project can be found here. Learn more about your ad choices. Visit megaphone.fm/adchoices