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In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss with disgust the decline and fall of American public health and the rise of "only me" when highlighting completion of the US withdrawal from the WHO and possibility of making IPV and MMR optional vaccines, before Dr. Griffin then deep dives into recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, Europe losing its measles elimination status, first measles death in Mexico, almost 1000 measles cases in South Carolina, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, the effectiveness of this season's influenza vaccine, where to go for answers to your long COVID questions and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode US completes withdrawal from World Health Organization (AP News) Rejecting Decades of Science, Vaccine Panel Chair Says Polio and Other Shots Should Be Optional (NY Times) A Frightening Interview (Beyond the Noise) Unexplained Pauses in Centers for Disease Control and Prevention Surveillance: Erosion of the Public Evidence Base for Health Policy (Annals of Internal Medicine) Wastewater for measles (WasterWater Scan) UK among 6 European countries losing measles elimination status (Dougall MD: DG Alerts) European Regional Verification Commission for Measles and Rubella Elimination (RVC) (WHO: Europe) Measles Outbreak Associated with an Infectious Traveler — Colorado, May–June 2025 (CDC: MMWR) South Carolina measles cases hit 789, surpassing Texas' 2025 outbreak total (Reuters) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) States across the country report first measles cases of year(CIDRAP) First measles death confirmed in Mexico in 2026 (Mexico News) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: cliff notes (CDC FluView) Influenza Vaccine Effectiveness Among Children With and Without Underlying Conditions(Pediatrics) OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Effectiveness and Durability of the BNT162b2 KP.2 vaccine against COVID-19 Hospitalization and Emergency Department or Urgent Care Encounters in US Adults (OFID) Where to get pemgarda (Pemgarda) EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Association of Nirmatrelvir-ritonavir with intubation or mortality risks in severe COVID-19 patients (BMC Infectious Diseases) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulationguidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Reaching out to US house representative Letters read on TWiV 1292 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.
We don't need to hide.Our guest this week shares this message loud and clear: as providers, we have nothing to hide from our patients.Dr. Erica Urquhart knows a thing or two about our healthcare system - having trained at Harvard as a biomedical engineer, she received a MD-PhD in Molecular and Neuroscience from Johns Hopkins and is now a practising orthopedic surgeon.She joins today to talk through her outlook on a broken system, as told in her upcoming book ‘Invisible Hand Wielding the Scalpel: Paying the Price in America's Fractured Healthcare System'.—We spoke about the value of transparency in healthcare, her constant battle with massive insurance companies, the capitalist emphasis in the system, the influence of commercial insurers in driving the cost and accessibility of care, and the fundamental importance of sickness prevention.Follow me on Instagram and Facebook @ericfethkemd and checkout my website at www.EricFethkeMD.com. My brand new book, The Privilege of Caring, is out now on Amazon! https://www.amazon.com/dp/B0CP6H6QN4
What if psychedelics could transform the way we treat trauma, chronic pain, and insomnia? This week, neuroscientist and psychedelic researcher Grace Blest-Hopley joins the show to break down the research on psychedelics and female biology. She discusses how psychedelics work in the brain, and the ways that psychedelic-assisted therapies might be beneficial for women in midlife. Links to resources mentioned in this episode: Hystelica’s resources on psychedelic retreats The Heroic Hearts Project Psychedelics and Neuroplasticity: A Systematic Review Unraveling the Biological Underpinnings of Psychedelics Exploring the Therapeutic Effects of Psychedelics Administered to Military Veterans in Naturalistic Retreat Settings The acute effects of classic psychedelics on memory in humans Psilocybin with psychological support for treatment-resistant depression: six-month follow-up Single-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial Johns Hopkins study on psychedelics and Alzheimer’s Note: In this show, we use “women” as shorthand for people with XX chromosomes. We understand sex and gender are more complex, and acknowledge the experiences we describe reach beyond that word.See omnystudio.com/listener for privacy information.
On this week’s episode, we’re continuing our Guidelines Series exploring the 2022 ESC/ERS Guidelines for the diagnosis and treatment of Pulmonary Hypertension. If you missed our first episode in the series, give it a listen to hear about the most recent recommendations regarding Pulmonary Hypertension definitions, screening, and diagnostics. Today, we’re talking about the next steps after diagnosis. Specifically, we’ll be discussing risk stratification, establishing treatment goals, and metrics for re-evaluation. We’ll additionally introduce the mainstays of pharmacologic therapy for Pulmonary Hypertension. Meet Our Co-Hosts Rupali Sood grew up in Las Vegas, Nevada and made her way over to Baltimore for medical school at Johns Hopkins. She then completed her internal medicine residency training at Massachusetts General Hospital before returning back to Johns Hopkins, where she is currently a pulmonary and critical care medicine fellow. Rupali’s interests include interstitial lung disease, particularly as related to oncologic drugs, and bedside medical education. Tom Di Vitantonio is originally from New Jersey and attended medical school at Rutgers, New Jersey Medical School in Newark. He then completed his internal medicine residency at Weill Cornell, where he also served as a chief resident. He currently is a pulmonary and critical care medicine fellow at Johns Hopkins, and he’s passionate about caring for critically ill patients, how we approach the management of pulmonary embolism, and also about medical education of trainees to help them be more confident and patient centered. Key Learning Points 1) Episode Roadmap How to set treatment goals, assess symptom burden, and risk-stratify patients with suspected/confirmed pulmonary arterial hypertension (PAH). What tools to use to re-evaluate patients on treatment Intro to major PAH medication classes and how they map to pathways. 2) Case-based diagnostic reasoning Patient: 37-year-old woman with exertional dyspnea, mild edema, abnormal echo, telangiectasias + epistaxis → raises suspicion for HHT (hereditary hemorrhagic telangiectasia) and/or early connective tissue disease. Key reasoning move: start broad (Groups 2–5) and narrow using history/exam/testing. In a young patient without obvious left heart or lung disease, think more about Group 1 PAH (idiopathic/heritable/associated). HHT teaching point: HHT can cause PH in more than one way: More common: high-output PH from AVMs (often hepatic/pulmonary) Rare (1–2% mentioned): true PAH phenotype (vascular remodeling; associated with ALK1 in some patients), behaving like Group 1 PAH. 3) Functional class assessment WHO Functional Class: Class I: no symptoms with ordinary activity, only with exertion Class II: symptoms with ordinary activity Class III: symptoms with less-than-ordinary activity (can't do usual chores/shopping without dyspnea) Class IV: symptoms at rest Practical bedside tip they give: Ask if the patient can walk at their own pace or keep up with a similar-age peer/partner. If not, think Class II (or worse). 4) Risk stratification at diagnosis: why, how, and which tools Big principle: treatment choices are driven by risk, and the goal is to move patients to low-risk quickly. ESC/ERS approach at diagnosis (as described): Use a 3-strata model predicting 1-year mortality: Low: 20% ESC/ERS risk assessment variables (10 domains discussed): Clinical progression, signs of right heart failure, syncope WHO FC Biomarkers (NT-proBNP) Exercise capacity (6MWD) Hemodynamics Imaging (echo; sometimes cardiac MRI) CPET (peak VO₂; VE/VCO₂ slope) They note: even if you don't have everything, the calculator can still be useful with ≥3 variables. REVEAL 2.0: Builds on similar core variables but adds further patient context (demographics, renal function, BP, DLCO, etc.) Case result: both tools put her in intermediate risk (ESC/ERS ~1.6; REVEAL 2.0 score 8), underscoring that mild symptoms can still equal meaningful mortality risk. 5) Treatment goals and follow-up philosophy What they explicitly prioritize: Help patients feel better, live longer, and stay out of the hospital Use risk tools to communicate prognosis and to track improvement Reassess frequently (they mention ~every 3 months early on) until low risk is achieved “Time-to-low-risk” is an important treatment goal Also emphasized: The diagnosis is psychologically heavy; patients need clear counseling, reassurance about the plan, and connection to support groups. 6) Medication classes for the treatment of PAH Nitric oxide–cGMP pathway PDE5 inhibitors: sildenafil, tadalafil Soluble guanylate cyclase stimulator: riociguat Important safety point: don't combine PDE5 inhibitors with riociguat (risk of significant hypotension/hemodynamic effects) Endothelin receptor antagonists (ERAs) “-sentan” drugs: bosentan (less used due to side effects/interactions), ambrisentan, macitentan Teratogenicity emphasized Hepatotoxicity that requires LFT monitoring Can cause fluid retention and peripheral edema Prostacyclin pathway Prostacyclin analogs/agonists: Epoprostenol (potent; short half-life; IV administration) Treprostinil (IV/SubQ/oral/inhaled options) Selexipag (oral prostacyclin receptor agonist) 7) Sotatercept (post-guidelines) They note sotatercept wasn't in 2022 ESC/ERS but is now “a game changer” in practice: Mechanism: ligand trap affecting TGF-β signaling / remodeling biology Positioned as potentially more disease-modifying than pure vasodilators Still evolving: where to place it earlier vs later in regimens is an active question in the field 8) How risk category maps to initial treatment intensity General approach they outline: High risk at diagnosis: parenteral prostacyclin (IV/SubQ) strongly favored, often aggressive early Intermediate risk: at least dual oral therapy (typically PDE5i + ERA); escalate if not achieving low risk Low risk: at least one oral agent; many still use dual oral depending on etiology/trajectory For the case: intermediate-risk → start dual oral therapy (they mention tadalafil + ambrisentan as a typical choice), reassess in ~3 months; add a third agent (e.g., selexipag/prostacyclin pathway) if not low risk. References and Further Reading Humbert M, Kovacs G, Hoeper MM, Badagliacca R, Berger RMF, Brida M, Carlsen J, Coats AJS, Escribano-Subias P, Ferrari P, Ferreira DS, Ghofrani HA, Giannakoulas G, Kiely DG, Mayer E, Meszaros G, Nagavci B, Olsson KM, Pepke-Zaba J, Quint JK, Rådegran G, Simonneau G, Sitbon O, Tonia T, Toshner M, Vachiery JL, Vonk Noordegraaf A, Delcroix M, Rosenkranz S; ESC/ERS Scientific Document Group. 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension. Eur Heart J. 2022 Oct 11;43(38):3618-3731. doi: 10.1093/eurheartj/ehac237. Erratum in: Eur Heart J. 2023 Apr 17;44(15):1312. doi: 10.1093/eurheartj/ehad005. PMID: 36017548. Condon DF, Nickel NP, Anderson R, Mirza S, de Jesus Perez VA. The 6th World Symposium on Pulmonary Hypertension: what’s old is new. F1000Res. 2019 Jun 19;8:F1000 Faculty Rev-888. doi: 10.12688/f1000research.18811.1. PMID: 31249672; PMCID: PMC6584967. Maron BA. Revised Definition of Pulmonary Hypertension and Approach to Management: A Clinical Primer. J Am Heart Assoc. 2023 Apr 18;12(8):e029024. doi: 10.1161/JAHA.122.029024. Epub 2023 Apr 7. PMID: 37026538; PMCID: PMC10227272. Hoeper MM, Badesch DB, Ghofrani HA, Gibbs JSR, Gomberg-Maitland M, McLaughlin VV, Preston IR, Souza R, Waxman AB, Grünig E, Kopeć G, Meyer G, Olsson KM, Rosenkranz S, Xu Y, Miller B, Fowler M, Butler J, Koglin J, de Oliveira Pena J, Humbert M; STELLAR Trial Investigators. Phase 3 Trial of Sotatercept for Treatment of Pulmonary Arterial Hypertension. N Engl J Med. 2023 Apr 20;388(16):1478-1490. doi: 10.1056/NEJMoa2213558. Epub 2023 Mar 6. PMID: 36877098. Ruopp NF, Cockrill BA. Diagnosis and Treatment of Pulmonary Arterial Hypertension: A Review. JAMA. 2022 Apr 12;327(14):1379-1391. doi: 10.1001/jama.2022.4402. Erratum in: JAMA. 2022 Sep 6;328(9):892. doi: 10.1001/jama.2022.13696. PMID: 35412560.
Episode Summary: In this conversation, Kimberly and Josh Redd delve into the critical topic of inflammation, exploring its prevalence, symptoms, and the various health conditions it can exacerbate, including autoimmune diseases and fertility issues. They discuss the impact of diet, gut health, and environmental toxins on inflammation, as well as the promising role of stem cell therapy in managing chronic inflammatory conditions. The conversation emphasizes the importance of education and proactive health management, encouraging listeners to take control of their health through informed lifestyle choices.Chapters00:00 The Rise of Inflammation Awareness03:04 Understanding Inflammation Symptoms05:59 Inflammation's Impact on Children09:00 Autoimmunity and Inflammation12:02 Dietary Influences on Inflammation14:51 The Role of Gut Health17:59 Environmental Toxins and Inflammation21:30 Big Picture Health Strategies23:53 Cooking and Nutrition Control25:25 Understanding Stem Cell Therapy28:56 Stem Cells and Inflammation31:55 Innovations in Stem Cell Treatments34:19 Insurance and Accessibility of TreatmentsSponsors: FATTY15 OFFER: Fatty15 is on a mission to replenish your C15 levels and restore your long-term health. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/KIMBERLY and using code KIMBERLY at checkout.USE LINK: fatty15.com/KIMBERLYDr. Josh Redd Resources: Book: THE 30-DAY INFLAMMATORY RESET: A Complete Guide to Healing Your Immune System Website: DrJoshRedd.com Tik Tok: drjoshred Instagram: @drjoshredd Bio: Dr. Josh Redd, NMD, MS, MPHb, is an industry leader in functional and personalized medicine. With over 12 years of post-graduate education—including two master's degrees and two doctorate degrees—he brings an unmatched depth of training and experience to his patients. His expertise in regenerative medicine includes over 1,000 precision-guided injections for spinal, joint, and soft tissue treatment, helping athletes and active individuals optimize performance and accelerate recovery. He holds an MS in Human Nutrition and Functional Medicine, an MPHb from Johns Hopkins (with an emphasis on molecular biology and immunology), and a Doctor of Chiropractic from Parker University. Most recently, he graduated from naturopathic medical school and completed his residency in regenerative medicine and stem cell injections through Bastyr University.Dr. Redd is the founder of RedRiver Health & Wellness, one of the largest functional medicine clinics in the U.S., with eight locations across Utah, New Mexico, Nevada, and Idaho, and PalmaVita Clinic, a regenerative medicine and athletic performance center in Spanish Fork, Utah.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Hormone therapy is not a panacea for everything that happens to a women transitioning through menopause, cautions Wen Shen, a menopause expert at Johns Hopkins. Now that the FDA has removed their black box warning from many forms of hormone … What are the benefits of hormone therapy for women in menopause and perimenopause? Elizabeth Tracey reports Read More »
If you're a woman who's experiencing a loss of libido, you may have been advised to take testosterone supplements, but Wen Shen, a menopause expert at Johns Hopkins, says wholesale embrace of hormone therapy isn't for everyone, in spite of … Women need to exercise caution when it comes to hormones of all types, Elizabeth Tracey reports Read More »
Hormone therapy for menopause has recently had a black box warning removed by the FDA, after the agency reexamined data originally prompting the warning and found it flawed. Wen Shen, a menopause expert at Johns Hopkins, says women still need … Caveat emptor when it comes to hormone therapy for menopause, Elizabeth Tracey reports Read More »
In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss screwworm, how the shingles vaccination slows biological aging (for all of you who want to reset 'the clock' and live forever…..you know who you are Musk, Bezos) and getting one dose of the HPV vaccine, then Dr. Griffin then deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, how losing our elimination status is the cost of doing business (going for broke is never a good business model !) where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, the effectiveness of this season's influenza vaccine, where to go for answers to your long COVID questions and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode New World Screwworm: Outbreak Moves into Northern Mexico……with an official tag "This is an official CDC Health Advisory" (CDC: Health Alert Network) Association between shingles vaccination andslower biological aging: Evidence from a U.S. population-based cohort study (The Journals of Gerontology series A) Noninferiority of One HPV Vaccine Dose to Two Doses (NEJM) Herd effect of human papillomavirus vaccination on incidence of high-grade cervical lesions: (LANCET: Public Health) Confirmations of Highly Pathogenic Avian Influenza in Commercial and Backyard Flocks (USDA: Animal and Plant Health Inspection Service) Detections of Highly Pathogenic Avian Influenza in Wild Birds (USDA: Animal and Plant Health Inspection Service) Delaware, Georgia see major commercial avian flu outbreaks (CIDRAP) Wastewater for measles (WasterWater Scan) Notes from the Field: Wastewater Surveillance for Measles Virus During a Measles Outbreak — Colorado, August 2025 (CDC: MMWR) Notes from the Field: Retrospective Analysis of Wild-Type Measles Virus in Wastewater During a Measles Outbreak — Oregon, March 24–September 22, 2024 (CDC: MMWR) Measles cases and outbreaks (CDC Rubeola) Measles vaccine recommendations from NYP (jpg) Tracking Measles Cases in the U.S. (Johns Hopkins) Utah measles total rises to 216; CDC deputy director says losing elimination status'cost of doing business' (CIDRAP) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Assessing MMR vaccination coverage gaps in US children with digital participatory surveillance (Nature Health) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) Effectiveness of influenza vaccination to prevent severe disease: a systematic review and meta-analysis of test-negative design studies (CMI: Clinical Microbiology and Infection) Interim vaccine effectiveness against influenza virus among outpatients, France, October 2025 to January 2026 (Eurosurveillance) Moderate protection from vaccination against influenza A(H3N2) subclade K in Beijing, China, September to December 2025 (Eurosurviellance) Current flu vaccine provides moderate protection against severe disease, interim analyses suggest (CIDRAP) OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virusnfection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Where to get pemgarda (Pemgarda) EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) UnderstandingCoverageOptions (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulationguidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Reaching out to US house representative Letters read on TWiV 1290 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.
Today's episode features Eileen Rivera Ley, a powerhouse at the intersection of business, innovation, and blindness advocacy. Eileen brings an impressive academic background, having earned a degree in economics from Harvard and an MBA from the Wharton School at the University of Pennsylvania. Her career includes work at the Wilmer Eye Institute at Johns Hopkins, but her entrepreneurial spirit ultimately led her to found Blind Savvy USA. Today, she serves as president of this innovative training and consulting company focused on low vision and blindness, helping organizations and individuals rethink what's possible through education, strategy, and lived experience.
The medical system expects you to chase 33 different screening appointments across multiple specialists and check your organs one at a time. But there's a smarter way that scans your entire body in under an hour to catch cancer, aneurysms, fatty liver, and other serious health issues before they become life-threatening. In today's episode, I sit down with Dr. Daniel Durand, Chief Medical Officer of Prenuvo, to talk about the real-world power (and limitations) of proactive whole-body MRI screening. Dr. Durand walks us through how this advanced screening method detects over 500 conditions, many of which traditional screenings miss. We talk about the importance of early detection for cancers and neurodegenerative diseases, and how this proactive approach to health can save lives. "It's better to see things early when you can intervene, and see them in a controlled context when you're healthy." ~ Dr. Daniel Durand In This Episode: - Introduction to Dr. Daniel Durand and his background - Conventional vs whole body scans - Conditions that whole-body MRI can detect - Bringing scans to underserved populations - Imaging for risk identification vs. diagnosis - How often you should rescan and what to expect - EMF exposure concerns and MRI safety parameters - How consumer demand is driving change in medicine Products & Resources Mentioned: Prenuvo Whole-Body MRI: My listeners get a special discount when you book at https://prenuvo.com/wendymyers Bon Charge Blue Light Blockers: Get 15% off with code WENDY at https://boncharge.com Organifi Happy Drops: Save 20% with code MYERSDETOX at https://organifi.com/myersdetox Organifi Collagen: Use code MYERSDETOX for 20% off at https://organifi.com/myersdetox Chef's Foundry P600 Ceramic Cookware: Get 20% off with code WENDY20 at https://chefsfoundry.com Heavy Metals Quiz: Take it for free at https://heavymetalsquiz.com About Dr. Daniel Durand: Dr. Daniel Durand is a dual board-certified adult & pediatric radiologist and Chief Medical Officer at Prenuvo, where he leads clinical operations, research, and the medical group for the world's largest network of proactive whole-body MRI clinics. Previously, he served as Chief Clinical Officer & Chief Innovation Officer at LifeBridge Health and held leadership roles in accountable care at Johns Hopkins. He is passionate about empowering primary care and shifting medicine toward true prevention through advanced imaging. Learn more at: https://prenuvo.com/wendymyers Disclaimer The Myers Detox Podcast was created and hosted by Dr. Wendy Myers. This podcast is for information purposes only. Statements and views expressed on this podcast are not medical advice. This podcast, including Wendy Myers and the producers, disclaims responsibility for any possible adverse effects from using the information contained herein. The opinions of guests are their own, and this podcast does not endorse or accept responsibility for statements made by guests. This podcast does not make any representations or warranties about guests' qualifications or credibility. Individuals on this podcast may have a direct or indirect financial interest in products or services referred to herein. If you think you have a medical problem, consult a licensed physician.
Dr Bill Nelson speaks with Dr Gabriel Ivey, a gastrointestinal surgeon based in the National Capital Region, about his practice, the progress being made in patient outcomes, and the range of care options available at Johns Hopkins in the greater Washington DC area.
Well, it's time. Let's talk about President Dallin Harris Oaks, the Hoaks man, the Mormon Gollum. First, we cover the biography In the Hands of the Lord: The Life of Dallin H. Oaks by Richard Turley. Then we take a look at Hoaks' book The Carthage Conspiracy, as well as a presentation from 2021 where he actually uttered a prophecy! And after all that, we share some amazing science news. Researchers at Johns Hopkins have uncovered a surprising new way to influence brain activity by targeting a long-mysterious class of proteins linked to anxiety, schizophrenia, and movement disorders. Enjoy! Show Notes: Cyrus Dallin Sculptor: https://en.wikipedia.org/wiki/Cyrus_Edwin_Dallin Cyrus Dallin: https://dallin.org/about-cyrus-dallin/ Stella Oaks Foundation: https://www.stellahoaks.org/ Law Review: https://en.wikipedia.org/wiki/Law_review Supreme Court case 1957-1958: https://www.oyez.org/cases/1957 Chief Justice Earl Warren: https://www.oyez.org/justices/earl_warren The Sit-In: 40 years later: https://chicagomaroon.com/22887/grey-city/the-sit-in-40-years-later/ Studying the Exclusionary Rule in Search and Seizure: https://nij.ojp.gov/library/publications/studying-exclusionary-rule-search-and-seizure Why Dress and Grooming Standards: https://www.youtube.com/watch?v=56pD3WMPQao Talk of the Month: Standards of Dress and Grooming: https://bhroberts.org/records/0spyAV-0Dx8uN/dallin_h_oaks_explains_byu_grooming_standards_in_the_new_era Internal Revenue Service Investigations of Unidentified Persons, Denver Law Review: chrome-extension://oemmndcbldboiebfnladdacbdfmadadm/https://digitalcommons.du.edu/cgi/viewcontent.cgi?article=2923&context=dlr United States vs Brigham Young University: https://law.justia.com/cases/federal/district-courts/FSupp/485/534/1377372/ The Wall Between Church and State: https://archive.org/details/wallbetweenchurc0000oaks/page/n5/mode/2up MoGP: Carthage Conspiracy by Dallin Oaks and Marvin Hill https://www.press.uillinois.edu/books/?id=p007620 Dallin Oaks Lecture Nov 12, 2021 @ University of Virginia Mormon Studies https://www.youtube.com/watch?v=A0r2YIAsOQs Happy News: A "dormant" brain protein turns out to be a powerful switch: https://www.sciencedaily.com/releases/2026/01/260118233607.htm Other appearances: Chris Shelton interviewed us in the beginning of a series on Mormonism on his Speaking of Cults series. Our most recent discussion was on the Mountain Meadows Massacre: https://youtu.be/iJWirjCyWdk He has had MANY different fascinating people on so go take a look! Here is the whole playlist: https://www.youtube.com/watch?v=OpGuS7GcsgA&list=PLGrPM1Pg2h72ADIuv8eYmzrJ-ppLOlw_g Email: glassboxpodcast@gmail.com Patreon: https://www.patreon.com/GlassBoxPod Patreon page for documentary: https://www.patreon.com/SeerStonedProductions BlueSky: @glassboxpodcast.bsky.social Other BlueSky: @bryceblankenagel.bsky.social and @shannongrover.bsky.social Instagram: https://www.instagram.com/glassboxpodcast/ Merch store: https://www.redbubble.com/people/exmoapparel/shop Or find the merch store by clicking on "Store" here: https://glassboxpodcast.com/index.html One time Paypal donation: bryceblankenagel@gmail.com Venmo: @Shannon-Grover-10
In this episode of the Award-winning PRS Journal Club Podcast, 2026 Resident Ambassadors to the PRS Editorial Board – Lucas Harrison, Christopher Kalmar, and Priyanka Naidu- and special guest, Shai Rozen, MD, discuss the following articles from the January 2026 issue: "Extended Sural Nerve Harvest: A Technique to Gain Additional Graft Length" by Millesi, Gates-Tanzer, Felzen, et al. Read the article for FREE: https://bit.ly/SuralNerveExt Special guest, Shai Rozen is Professor and Vice-Chairman in the Department of Plastic Surgery at the University of Texas Southwestern Medical Center and Director of the Facial Reanimation Program, specializing in treating patients with facial paralysis. He completed both general surgery and plastic surgery training at Johns Hopkins, followed by fellowships in both craniofacial and peripheral nerve surgery. READ the articles discussed in this podcast as well as free related content: https://bit.ly/JCJan26Collection The views expressed by hosts and guests are their own and do not necessarily reflect the official policies or positions of ASPS.
Summary In this episode, two university presidents, Dr. Sally Kornbluth (MIT) and Ron Daniels (Johns Hopkins) join Rob to talk about adult-onset Type 1 (LADA), leading in high-performance environments, and the single most “practical” diabetes upgrade: making a friend with diabetes. What stands out isn't prestige—it's how candidly they describe the everyday realities: managing highs and lows during major speeches, checking pumps in meetings, and staying open about diabetes to normalize it for everyone around them. The conversation also connects diabetes progress to the university research engine—past (insulin's discovery era) and future (stem cell/islet replacement, closed-loop algorithms, and emerging trials). Chapters * 00:26: Diagnosis stories through high-performance leadership lens + “patients first” approach * 01:02: Sally Kornbluth's adult-onset Type 1 (LADA) diagnosis * 02:55: Ron Daniels' adult-onset Type 1 diagnosis * 06:08: Adult-onset Type 1, LADA, and misdiagnosis risk * 08:29: Carbs, discipline, and the real lifestyle tradeoffs * 10:19: The biggest adjustment: mental load + fear of lows * 13:30: How they found each other + why “a friend with diabetes” changes everything * 21:41: Universities power diabetes progress (and what's next) * 42:45: Closing lessons: openness, resilience, and gratitude Resources Dr. Sally Kornbluth Ron Daniels
The offseason is HERE. But D1R does not sleep! We're joined by the Head Coach of Ottawa (KS) Nick Davis who led the Braves to a 6-5 record in 2025. We talk high school recruiting, culture and NAIA changing the game. Our Division 2 conversation revolves around the Harlon Hill winner Curtis Allen from Virginia Union and the Cliff Harris Award winner Justin Payoute from Ferris State, along with an interesting move from one of the top coaches in the country.In Division 3 we review some NCAA proposals that were denied/approved that could seriously alter the game, take a look at John Sullivan's incredible season at North Central, highlight an exciting new series between Johns Hopkins and Trinity (TX), and celebrate higher TV ratings for the Stagg Bowl!The NAIA conversation surrounds a contest with Northwestern scheduling FCS competition and Indiana Wesleyan signing a first-of-it's-kind media rights deal with Urban Edge Network. Thanks for tuning in!Video Chapters:0:00 Episode Overview3:34 Nick Davis - Ottawa Braves27:56 Curtis Allen's Harlon Hill Season33:23 Paul Simmons move to GM for Harding Football43:51 Justin Payoute - Cliff Harris Winner53:09 Trinity and Johns Hopkins New Series58:52 NCAA Proposals Changing the Game1:11:22 John Sullivan - Cliff Harris Winner1:17:38 Stagg Bowl Viewership Spike1:25:28 Northwestern schedules FCS Western IL1:34:25 Indiana Wesleyan's New Media Rights Deal
The American Cancer Society has updated guidelines for cervical cancer screening to include self-collected specimens to assess for human papilloma virus, or HPV. William Nelson, director of the Kimmel Cancer Center at Johns Hopkins, explains why. Nelson: There's 200,000 women … Will women soon be testing themselves for human papilloma virus, or HPV ? Elizabeth Tracey reports Read More »
For people who've had colorectal cancer, celecoxib, a commonly prescribed medicine for pain, may help avoid disease recurrence, a recent analysis of a larger study found. Kimmel Cancer Center director William Nelson at Johns Hopkins explains that the presence of … Can the drug celecoxib help some people avoid colorectal cancer recurrence? Elizabeth Tracey reports Read More »
In his weekly clinical update, Dr. Griffin and Vincent Racaniello are bewildered and dismayed by RFK Jr's announced changes in the routine childhood immunization schedule, though not unpredicted, and highlight the science and evidence which eviscerate these changes, then deep dives into recent statistics on the measles epidemic- in particular in South Carolina, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, estimated societal burden of COVID-19 illness, deaths and hospitalizations, benefit of maternal COVID-19 vaccination, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, neurodevelopmental consequences of in-utero SARS-CoV-2 infection and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode 7 great Danish cheeses you should know (Cheese Professor) Norovirus in on the rise! (WasterWater Scan) Maternal Vaccine Receipt and Infant Hospital and Emergency Visits for Influenza and Pertussis (JAMA Open) TUESDAY MEASLES UPDATE: DPH Reports 124 New Measles Cases in Upstate, New Public Exposures, and Upcoming Vaccination Opportunities (South Carolina: Department of Public Health-they have one?) Measles cases soar in South Carolina, top 400 (CIDRAP) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) USrespiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: cliff notes (CDC FluView) North Dakota confirms pediatric flu deaths as some states note surge in flu activity (CIDRAP) OPTION 2: XOFLUZA $50 Cash Pay Option (Xofluza) The Best Flu Drug Americans Aren't Taking (The Atlantic) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season(FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) Impact of universal nirsevimab prophylaxis in infants on hospital and primary care outcomes across two respiratory syncytial virus seasons in Galicia, Spain (NIRSE-GAL): a population-based prospective observational study (Lancet: Infectious Diseases) Interim Safety of RSVpreF Vaccination During Pregnancy (JAMA) Pfizer's RSV vaccine safe to use during pregnancy, study suggests (CIDRAP) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Evaluating the Effectiveness of 2024–2025 Seasonal mRNA-1273 Vaccination Against COVID-19-Related Hospitalizations and Medically Attended COVID-19 Among Adults Aged ≥ 18 years in the United States: An Observational Matched Cohort Study (Infectious Diseases and Therapy) Where to get pemgarda (Pemgarda) EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) UnderstandingCoverageOptions (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) Use of corticosteroids in influenza-associated acute respiratory distress syndrome and severe pneumonia: a systemic review and meta-analysis(Scientific Reports) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulationguidelines (hematology.org Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Incidence and Severity of Postacute Sequelae of SARS-CoV-2 Infection in the Omicron Era: A Prospective Cohort Study (JID) Reaching out to US house representative Letters read on TWiV 1288 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.
NASA's SpaceX Crew-11 has returned to Earth, concluding a more than five-month mission aboard the International Space Station (ISS). Slingshot Aerospace has been awarded a $27 million US Space Force (USSF) contract to modernize scenario training activities. Chinese commercial company CAS Space debuted its suborbital two-stage research rocket, and more. Remember to leave us a 5-star rating and review in your favorite podcast app. Be sure to follow T-Minus on LinkedIn and Instagram. T-Minus Guest Our guest today is Cherie Matthew, Architect/ Project Manager at Jacobs. You can connect with Cherie on LinkedIn, and learn more about Jacobs on their website. Selected Reading NASA's SpaceX Crew-11 Mission Returns, Splashes Down off California Slingshot Aerospace Awarded $27 Million Space Force Contract to Power the AI-Driven Training Environment for Space Warfare CAS Space Debuts Suborbital Research and Technology Testing Rocket Axelspace Signs MoU with Ethiopian Company to Address Social Challenges through the Utilization of Satellite Data Space Force Teams with Universities to Advance Sonic Boom Research in California NASA and Johns Hopkins play the cult video game DOOM on satellites Share your feedback. What do you think about T-Minus Space Daily? Please take a few minutes to share your thoughts with us by completing our brief listener survey. Thank you for helping us continue to improve our show. Want to hear your company in the show? You too can reach the most influential leaders and operators in the industry. Here's our media kit. Contact us at space@n2k.com to request more info. Want to join us for an interview? Please send your pitch to space-editor@n2k.com and include your name, affiliation, and topic proposal. T-Minus is a production of N2K Networks, your source for strategic workforce intelligence. © N2K Networks, Inc. Learn more about your ad choices. Visit megaphone.fm/adchoices
Dr. Don Watenpaugh is a scientist, sleep clinician, data artist, and poet with a PhD in physiology. His extensive career spans academia, NASA, and the U.S. Navy, focusing on human sleep, exercise, and environmental physiology. As a board-certified sleep medicine specialist, he directed a large urban sleep clinic for over 13 years, caring for patients and educating healthcare providers. Dr. Watenpaugh is an adjunct faculty member in physiology, anatomy, and biomedical engineering. He now creates data-driven art and poetry at Studio Videnda. In this episode, he brings his deep expertise to the critical relationship between sleep and concussion recovery.Episode Summary:In this episode of the Concussion Coach Podcast, host Bethany Lewis welcomes sleep expert Dr. Don Watenpaugh, to explore the complex connection between sleep disturbances and concussion recovery. Dr. Watenpaugh explains the physiological reasons why concussions commonly disrupt sleep—from brain inflammation impacting cerebral spinal fluid "brainwashing" during non-REM sleep to the exacerbation of pre-existing conditions like PTSD, depression, and anxiety. The conversation delves into the different types of insomnia (sleep onset and maintenance) and their potential causes, including restless leg syndrome and sleep apnea.Crucially, Dr. Watenpaugh provides actionable, evidence-based strategies to improve sleep and support brain healing. He discusses the evolving role of exercise as medicine, emphasizing safe, non-jarring activities like stationary cycling. He covers practical sleep hygiene tips, such as the importance of spinal alignment during sleep, the potential benefits of slightly elevating the head of the bed, and the disruptive effects of electronics and blue light. The discussion also touches on the careful use of supplements like melatonin, the special considerations for military personnel and student-athletes, and the overarching importance of patient education and self-advocacy. This episode is packed with science-backed insights to help listeners break the vicious cycle of poor sleep and prolonged concussion symptoms.Key Resources & Strategies Mentioned:Exercise as Medicine: Safe, mild-to-moderate exercise (e.g., stationary cycling to avoid head acceleration) can aid concussion recovery and improve sleep. Always consult your doctor.Sleep Position & Environment:Maintain spinal alignment; avoid stomach sleeping to prevent neck torsion.Consider slightly elevating the head of the bed to help reduce intracranial pressure.Remove electronics (TVs, phones) from the bedroom to avoid mental stimulation and blue light, which suppresses natural melatonin.Addressing Underlying Causes:Restless Leg Syndrome (RLS): Evening exercise (ending 2+ hours before bed) can help. Other treatments are available.Sleep Apnea: A common cause of sleep maintenance insomnia. Treatment (e.g., CPAP) is critical for overall health and concussion recovery.Hormonal Factors: Post-menopausal women may see a link between hormone changes and sleep apnea onset.Melatonin & Supplements: Prioritize natural melatonin production by managing light exposure. If using supplements, start with a low dose well before bedtime, monitor for side effects like headaches or grogginess, and consult your doctor.Patient Advocacy & Reliable Research: Dr. Watenpaugh stresses the importance of educating yourself using reliable, peer-reviewed sources like PubMed/MEDLINE, reputable medical institutions (e.g., Johns Hopkins & the Mayo Clinic), and professional organizations (e.g., American Academy of Sleep Medicine).Dr. Don Watenpaugh's website:Website/Data Art Studio: https://www.studiovidenda.comBethany Lewis & The Concussion Coach:Free Guide: "5 Best Ways to Support Your Loved One Dealing with a Concussion" - Download at www.theconcussioncoach.comConcussion Coaching Program: For personalized mentorship in recovery. Sign up for a free consultation HERE
In this episode of the Award-winning PRS Journal Club Podcast, 2026 Resident Ambassadors to the PRS Editorial Board – Lucas Harrison, Christopher Kalmar, and Priyanka Naidu- and special guest, Shai Rozen, MD, discuss the following articles from the January 2026 issue: "The Natural Progression of Synkinesis" by Rail, Bhatia, Dragun, et al. Read the article for FREE: https://bit.ly/NaturalSynk Special guest, Shai Rozen is Professor and Vice-Chairman in the Department of Plastic Surgery at the University of Texas Southwestern Medical Center and Director of the Facial Reanimation Program, specializing in treating patients with facial paralysis. He completed both general surgery and plastic surgery training at Johns Hopkins, followed by fellowships in both craniofacial and peripheral nerve surgery. READ the articles discussed in this podcast as well as free related content: https://bit.ly/JCJan26Collection The views expressed by hosts and guests are their own and do not necessarily reflect the official policies or positions of ASPS.
Protests are sweeping Iran and the government is cracking down hard, fearing the uprisings pose a threat to the theocratic regime. There is an internet blackout in the country making it hard to get information. We hear a rare first-person account of the protests from a Johns Hopkins professor who visits the Iran frequently and who recently attended a protest there.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy
We kicked off the program with four news stories and different guests on the stories we think you need to know about! THE POWER OF THE PAUSE: 90 Seconds to Calm, Reset, and Reconnect.Guest: Jillian Pransky – Author & mindfulness teacher & Yoga therapist 5 Ways to Use AI for a Healthier 2026. Accessible AI tools and affordable wearables can simplify healthy habits rather than overwhelm people. New Book: Better Health with AI: Simple Steps to Real ResultsGuest: Dr. Earl J. Campazzi, Jr, a Johns Hopkins–trained preventive medicine physician with 35+ years of clinical experience and four board certifications Why you should put down your phone and daydream insteadGuest: Maggie Penman – WaPo Reporter In reversal, U.S. loosens guidance on alcoholGuest: David Ovalle – WaPo Reporter that focuses on opioids and addiction See omnystudio.com/listener for privacy information.
Luke Hedrick, Dave Furfaro, and recurrent RFJC guest Robert Wharton are joined again today by Nicole Ng to discuss the FIBRONEER-IPF trial investigating Nerandomilast in patients with IPF. This trial was published in NEJM in 2025 and looked at Neradomilast vs placebo for treating patients with IPF, on or off background anti-fibrotic therapy. This agents is now FDA approved for pulmonary fibrosis, and understanding the trial results is essential for any pulmonary physician treating patients with IPF or progressive pulmonary fibrosis. Article and Reference Today’s episode discusses the FIBRONEER-IPF trial published in NEJM in 2025. Richeldi L, Azuma A, Cottin V, Kreuter M, Maher TM, Martinez FJ, Oldham JM, Valenzuela C, Clerisme-Beaty E, Gordat M, Wachtlin D, Liu Y, Schlecker C, Stowasser S, Zoz DF, Wijsenbeek MS; FIBRONEER-IPF Trial Investigators. Nerandomilast in Patients with Idiopathic Pulmonary Fibrosis. N Engl J Med. 2025 Jun 12;392(22):2193-2202. doi: 10.1056/NEJMoa2414108. Epub 2025 May 18. PMID: 40387033. https://www.nejm.org/doi/abs/10.1056/NEJMoa2414108 Meet Our Guests Luke Hedrick is an Associate Editor at Pulm PEEPs and runs the Rapid Fire Journal Club Series. He is a senior PCCM fellow at Emory, and will be starting as a pulmonary attending at Duke University next year. Robert Wharton is a recurring guest on Pulm PEEPs as a part of our Rapid Fire Journal Club Series. He completed his internal medicine residency at Mt. Sinai in New York City, and is currently a pulmonary and critical care fellow at Johns Hopkins. Dr. Nicole Ng is an Assistant Profess of Medicine at Mount Sinai Hospital, and is the Associate Director of the Interstitial Lung Disease Program for the Mount Sinai National Jewish Health Respiratory Institute. Infographic Key Learning Points Why this trial mattered IPF therapies remain limited: nintedanib and pirfenidone slow (but do not stop) decline and often cause GI side effects. Nerandomilast is a newer agent (a preferential PDE4B inhibitor) with antifibrotic + immunomodulatory effects. Phase 2 data (NEJM 2022) looked very promising (suggesting near-“halt” of FVC decline), so this phase 3 trial was a big test of that signal. Trial design essentials Industry-sponsored, randomized, double-blind, placebo-controlled, large multinational study (332 sites, 36 countries). Population: IPF diagnosed via guideline-aligned criteria with central imaging review and multidisciplinary diagnostic confirmation. Intervention: nerandomilast 18 mg BID, 9 mg BID, or placebo; stratified by background antifibrotic use. Primary endpoint: change in FVC at 52 weeks, analyzed with a mixed model for repeated measures. Key secondary endpoint: time to first acute exacerbation, respiratory hospitalization, or death (composite). Who was enrolled Typical IPF trial demographics: ~80% male, mean age ~70, many former smokers. Many were already on background therapy (~45% nintedanib, ~30–33% pirfenidone). Notable exclusions included significant liver disease, advanced CKD, recent major cardiovascular events, and psychiatric risk (suicidality/severe depression), reflecting class concerns seen with other PDE4 inhibitors. Efficacy: what the primary endpoint showed Nerandomilast produced a statistically significant but modest reduction in annual FVC decline vs placebo (roughly 60–70 mL difference). Importantly, it did not halt FVC decline the way the phase 2 data suggested; patients still progressed. Important nuance: interaction with pirfenidone Patients on pirfenidone had ~50% lower nerandomilast trough levels. Clinically: 9 mg BID looked ineffective with pirfenidone, so 18 mg BID is needed if used together. In those not on background therapy or on nintedanib, 9 mg and 18 mg looked similar—suggesting the apparent “dose-response” might be partly driven by the pirfenidone drug interaction Secondary and patient-centered outcomes were neutral No demonstrated benefit in the composite outcome (exacerbation/resp hospitalization/death) or its components. Quality of life measures were neutral and declined in all groups, emphasizing that slowing FVC alone may not translate into felt improvement without a disease-reversing therapy. The discussants noted this may reflect limited power/duration for these outcomes and mentioned signals from other datasets/pooling that might suggest mortality benefit—but in this specific trial, the key secondary endpoint was not positive. Safety and tolerability Diarrhea was the main adverse event: Higher overall with the 18 mg dose, and highest when combined with nintedanib (up to ~62%). Mostly mild/manageable; discontinuation due to diarrhea was relatively uncommon (but higher in those on nintedanib). Reassuringly, there was no signal for increased depression/suicidality/vasculitis despite psychiatric exclusions and theoretical class risk. How to interpret “modest FVC benefit” clinically The group framed nerandomilast as another tool that adds incremental slowing of progression. They emphasized that comparing absolute FVC differences across trials (ASCEND/INPULSIS vs this trial) is tricky because populations and “natural history” in placebo arms have changed over time (earlier diagnosis, improved supportive care, etc.). They highlighted channeling bias: patients already on antifibrotics may be sicker (longer disease duration, lower PFTs, more oxygen), complicating subgroup comparisons. Practical takeaways for real-world use All three antifibrotics are “fair game”; choice should be shared decision-making based on goals, tolerability, dosing preferences, and logistics. Reasons they favored nerandomilast in practice: No routine lab monitoring (major convenience advantage vs traditional antifibrotics). Generally better GI tolerability than nintedanib. BID dosing (vs pirfenidone TID). Approach to combination therapy: They generally favor add-on rather than immediate combination to reduce confusion about side effects—while acknowledging it may slow reaching “maximal therapy.” Dosing guidance emphasized: Start 18 mg BID for IPF, especially if combined with pirfenidone (since dose reduction may make it ineffective). 9 mg BID may be considered if dose reduction is needed and the patient is not on pirfenidone (e.g., monotherapy or with nintedanib).
414 Following Your Own Star There comes a time in our lives where we need to stop and take stock of what we want to do next and our next steps in getting there. Perhaps it's more than just one thing, perhaps you're just floating through life trying to figure out what to do next, or perhaps you think this goal is too lofty despite all your hard work. Which is why it is so important to take all you know about others and yourself and apply it to whatever comes next. In today's episode Sarah Elkins and Professor KD Frick discuss the importance of that specific personal growth, as well as the importance of believing in others and yourself even when you aren't sure where your own star is leading you, and especially to greet the world with open arms. Highlights Finding the right words for where you are in your life right now. Leading with compassion and empathy. Position yourself to be able to understand. Don't immediately dismiss someone, you never know where their combined ideas may lead. Everyone has their own North Star they follow. Quotes "Empathy leads to approachability." "Look as long as I'm here and unless you tell me otherwise, I'm planning on reading names. Because it's the last connection students have with us." Dear Listeners it is now your turn, What did you hear in this conversation that struck you as something that resonated? Maybe it was about not knowing what you want to do next, maybe it was I do know what I want to do next but I'm not being consistent enough to make it happen. I am so curious to hear your thoughts, please share them either in the comments or wherever you see this shared or send me an email. And, as always, thank you for listening. About KD KD Frick was originally trained as a health economist and began a career at Johns Hopkins as a faculty member at the Bloomberg School of Public Health; after a bit more than sixteen years in that role, with responsibilities like associate department chair and faculty senate president, a move was made to the Carey Business School as vice dean for education. The eight and one-half years spent in that role were a time of growth and expansion of opportunity. With colleagues encouraging a return to research, challenging decisions around COVID, a focus on ranking academic programs that was not of interest, and a lack of visible opportunities for advancement in administration, a decision was made to return to just a faculty role. The result has been great fulfillment, a change in teaching, and a focus on leading by teaching others to lead artisnally toward aspirational narratives for themselves and those they are developing. There is still room for work on the economics of eye care where Professor Frick has the opportunity to apply the leading with values approach that is taught in the classroom. Be sure to check out Professor Frick's LinkedIn, thoughts on tHERSday newsletter, as well as Business and Economics of Eye Care and Health! About Sarah "Uncovering the right stories for the right audiences so executives, leaders, public speakers, and job seekers can clearly and actively demonstrate their character, values, and vision." In my work with coaching clients, I guide people to improve their communication using storytelling as the foundation of our work together. What I've realized over years of coaching and podcasting is that the majority of people don't realize the impact of the stories they share - on their internal messages, and on the people they're sharing them with. My work with leaders and people who aspire to be leaders follows a similar path to the interviews on my podcast, uncovering pivotal moments in their lives and learning how to share them to connect more authentically with others, to make their presentations and speaking more engaging, to reveal patterns that have kept them stuck or moved them forward, and to improve their relationships at work and at home. The audiobook, Your Stories Don't Define You, How You Tell Them Will is now available! Included with your purchase are two bonus tracks, songs recorded by Sarah's band, Spare Change, in her living room in Montana. Be sure to check out the Storytelling For Professionals Course as well to make sure you nail that next interview!
Dr. James Greenblatt, MD, is more than a dual board-certified psychiatrist; he is a pioneer of hope and a tireless advocate for the integration of soul and science. For over 30 years, Dr. Greenblatt has looked beyond the traditional "checklist" of symptoms to uncover the vibrant, biochemical story beneath. As the leading global expert on the clinical application of low-dose lithium and a pioneer in functional psychiatry, he has dedicated his career to a singular, transformative mission: healing the root cause so the spirit can flourish. From his academic roots at Johns Hopkins and George Washington University to his current faculty roles at Tufts and Dartmouth, Dr. Greenblatt bridges the gap between clinical excellence and compassionate, precision-based care. Through his educational platform, Psychiatry Redefined, he is shifting the global landscape of mental health—empowering a new generation of clinicians to treat the whole person rather than just the diagnosis. A prolific voice in the holistic movement, Dr. Greenblatt has authored nine life-changing books, including the bestsellers Finally Focused and Nutritional Lithium. His work invites us to reimagine what is possible for our mental well-being, moving away from temporary fixes toward a state of true, sustainable inner balance. Whether through his writing or his upcoming 2026 release, Finally Hopeful, Dr. Greenblatt continues to light the path for those seeking to reclaim their health, their clarity, and their lives.
Mifepristone used with misoprostol is the most common abortion regimen in the US. It is also a focal point of reproductive health policy and politics, with controversy over its legal status and regulation by the US Food and Drug Administration (FDA). Author G. Caleb Alexander, MD, MS, from Johns Hopkins discusses this and more with JAMA Deputy Editor Joseph S. Ross, MD, MHS. Related Content: The US Food and Drug Administration's Regulation of Mifepristone Politics, Science, and the Future of FDA Drug Regulation
This week, Tee sits down with Dr. Beverly Jensen for a powerful conversation on the often-overlooked impact of electromagnetic fields (EMFs) on our health, homes, and especially our children. Dr. Beverly brings a rare blend of academic rigor, international experience, and lived wisdom. Her early career included writing on health, nutrition, and environmental education for Woman's Day, Teacher, and McGraw-Hill. She later earned her doctorate in international communication from the University of Washington and went on to build a global career spanning Egypt, the Czech Republic, and the UAE. From launching a nationally adopted noise-abatement campaign in Egypt to managing a World Bank–backed Heart Association project in the Czech Republic, Dr. Jensen has spent decades at the intersection of public health, communication, and advocacy. She also co-managed a Johns Hopkins–affiliated health promotion program in the UAE, helping shape initiatives later adopted by the Abu Dhabi Health Authority. In this episode, Tee and Dr. Jensen explore how everyday EMF exposure from cell phones to household appliances can affect daily life and childhood development. Dr. Jensen shares her personal journey into EMF awareness, practical steps families can take to reduce exposure, and why public education and legislative involvement are urgently needed. The conversation also highlights the vital role mothers play in advocating for children's long-term health. Connect with Dr.Beverly: You and EMF Women's Medicine Bowl Free Consultation LinkedIn Facebook YouTube Contact Your Representative Regarding House Bill 2289 National Call For Safe Technology Follow Therese "Tee" Forton-Barnes and The Green Living Gurus: Austin Air Purifiers: For podcast listeners, take 15% off any Austin Air product; please email Tee@thegreenlivinggurus.com and mention that you want to buy a product and would like the discount. See all products here: Austin Air The Green Living Gurus' Website Instagram YouTube Facebook Healthy Living Group on Facebook Tip the podcaster! Support Tee and the endless information that she provides: Patreon Venmo: @Therese-Forton-Barnes last four digits of her cell are 8868 For further info, contact Tee: Email: Tee@thegreenlivinggurus.com Cell: 716-868-8868 DISCLAIMER: ALL INFORMATION PROVIDED HERE IS GENERAL GUIDANCE AND NOT MEANT TO BE USED FOR INDIVIDUAL TREATMENT. PLEASE CONTACT YOUR PROVIDER OR DOCTOR FOR MEDICAL ADVICE. Produced By: Social Chameleon
This and all episodes at: https://aiandyou.net/ . What's going on with getting AI education into America's classrooms? We're finding out from Jeff Riley, former Commissioner of Education for the state of Massachusetts and founder of a new organization – Day of AI, started by MIT's Responsible AI for Social Empowerment and Education institute. And they are mounting a campaign called Responsible AI for America's Youth, which is now running across all 50 states and will run an event called America's Youth AI Festival in July 2026 in Boston. Jeff has got master's degrees from Johns Hopkins and Harvard. He was a Boston school principal and as commissioner, successfully navigated Massachusetts schools through Covid and other crises. In our conclusion, we talk about how Jeff sees the AI education of teachers evolving, responsible use of AI by students, differentiated learning, making AI in classrooms safe for teachers and students, the impact of AI on educational inequalities, the future of educational reform, and how you can get involved in AI in schools. All this plus our usual look at today's AI headlines. Transcript and URLs referenced at HumanCusp Blog.
Early introduction of peanut into a child's diet may help them avoid development of peanut allergy, a recent study concludes. Robert Wood, a childhood allergy expert at Johns Hopkins, says it's just not that simple when it comes to understanding … Should you feed your young child peanut to prevent allergy? Elizabeth Tracey reports Read More »
Early exposure to peanut is credited with reducing the development of peanut allergy in young children, a recent study concludes, but Robert Wood, a childhood allergy expert at Johns Hopkins, says the rate of food allergies among children is increasing … What's the best strategy to avoid food allergies in young children? Elizabeth Tracey reports Read More »
Eight different cancers are increasing among those younger than fifty in the US, data since 1992 indicate. William Nelson, director of the Kimmel Cancer Center at Johns Hopkins, says thyroid, colorectal and endometrial or uterine are included in that number, … Cancers increasing among those younger than fifty warrant investigation to discern causes, Elizabeth Tracey reports Read More »
In his weekly clinical update, Dr. Griffin and Vincent Racaniello are bewildered and dismayed by RFK Jr's announced changes in the routine childhood immunization schedule, though not unpredicted, and highlight the science and evidence which eviscerate these changes, then deep dives into recent statistics on the measles epidemic- in particular in South Carolina, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, estimated societal burden of COVID-19 illness, deaths and hospitalizations, benefit of maternal COVID-19 vaccination, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, neurodevelopmental consequences of in-utero SARS-CoV-2 infection and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Childhood Immunization Schedule by Recommendation Group (US Health and Human Service) Recommended Child and Adolescent Immunization Schedule for Ages 18 Years or Younger (American Academy of Pediatrics) Kennedy Scales Back the Number of Vaccines Recommended for Children (NY Times) There RFK Jr. Goes Again . . .(Wall Street Journal) Hepatitis B Vaccination is an Essential Safety Net for Newborns (Johns Hopkins Bloomberg School of Public Health) Effectiveness and Impact of Maternal RSV Immunization and Nirsevimab on Medically Attended RSV in US Children (JAMA Pediatrics) Rotavirus (College of Physicians of Philadelphia) Hepatitis A in the Era of Vaccination (Epidemiologic Reviews) Meningococcal Vaccination in the United States: Past, Present, And Future (Ped Drugs) Meningococcal Vaccination: Recommendations of the Advisory Committee on Immunization Practices, United States, 2020 (CDC: MMWR) N.Y. DOH says childhood vaccine recommendations remain unchanged despite CDC's update (Spectrum 1 News) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) South Carolina measles cases rise by 26 to 211, state health department says (Reuters) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: cliff notes (CDC FluView) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) Estimated Burden of COVID-19 Illnesses, Medical Visits, Hospitalizations, and Deaths in the US From October 2022 to September 2024 (JAMA Internal Medicine) The Role of Vaccination in Maternal and Perinatal Outcomes Associated With COVID-19 in Pregnancy (JAMA) Where to get pemgarda (Pemgarda) EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) UnderstandingCoverageOptions (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulationguidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID The COVID generation: the neurodevelopmental consequences of in-utero COVID-19 exposure (Brain, behavior and Immunity) Reaching out to US house representative Letters read on TWiV 1286 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.
In this episode of the Award-winning PRS Journal Club Podcast, 2026 Resident Ambassadors to the PRS Editorial Board – Lucas Harrison, Christopher Kalmar, and Priyanka Naidu- and special guest, Shai Rozen, MD, discuss the following articles from the January 2026 issue: "The Efficacy of Flap Debulking after Facial Reanimation Surgery to Enhance Facial Symmetry" by Weiss, Fricke, Hohenstein, et al. Read the article for FREE: https://bit.ly/FlapDebulk Special guest, Shai Rozen is Professor and Vice-Chairman in the Department of Plastic Surgery at the University of Texas Southwestern Medical Center and Director of the Facial Reanimation Program, specializing in treating patients with facial paralysis. He completed both general surgery and plastic surgery training at Johns Hopkins, followed by fellowships in both craniofacial and peripheral nerve surgery. READ the articles discussed in this podcast as well as free related content: https://bit.ly/JCJan26Collection The views expressed by hosts and guests are their own and do not necessarily reflect the official policies or positions of ASPS.
Welcome to The Chrisman Commentary, your go-to daily mortgage news podcast, where industry insights meet expert analysis. Hosted by Robbie Chrisman, this podcast delivers the latest updates on mortgage rates, capital markets, and the forces shaping the housing finance landscape. Whether you're a seasoned professional or just looking to stay informed, you'll get clear, concise breakdowns of market trends and economic shifts that impact the mortgage world.In today's episode, we look at how the residential lending space is impacting overall home affordability. Plus, Robbie sits down with Johns Hopkins' Dan Ye for a discussion on how 90 percent of human capital will be replaced in the next 10 years through AI, and how you can potentially ward off the impending doom. And we close by reviewing why rates are treading water to open 2026.
Dr. Otis Brawley of Johns Hopkins shares his insight about cancer screening, focusing on prostate cancer. Dr. Brawley explains that while prostate cancer is common and serious, evidence supporting routine PSA screening is limited and inconsistent, leading major organizations to recommend shared decision-making between doctors and patients rather than universal screening. Men of Northwestern Sub-Saharan African ancestry have higher risk, but outcomes are equal across groups when high-quality care is provided, highlighting that disparities stem mainly from access to care, not biology. He emphasizes the importance of individualized screening decisions, treatment at strong medical centers, and patient engagement, and briefly describes Johns Hopkins' MAPS peer-support program for cancer patients.
New year's greetings from PreserveCast! Today we're talking with Lori Beth Finkelstein and Michelle Fitzgerald from Johns Hopkins museums about Homewood Museum's recently opened If Homewood's Walls Could Talk: A History of an American House. Lori is the Philip Franklin Wagley Director & Curator of Johns Hopkins University's Evergreen Museum & Library and Director of Homewood Museum. Michelle is the Curator of Collections at Johns Hopkins University Museums, which is comprised of the university's two historic houses, Homewood Museum and Evergreen Museum & Library. She has curated several exhibitions at Hopkins, including the new Homewood exhibit.
This and all episodes at: https://aiandyou.net/ . What's going on with getting AI education into America's classrooms? We're going to find out from Jeff Riley, former Commissioner of Education for the state of Massachusetts and founder of a new organization – Day of AI, started by MIT's Responsible AI for Social Empowerment and Education institute. And they are mounting a campaign called Responsible AI for America's Youth, which is now running across all 50 states and will run an event called America's Youth AI Festival in July 2026 in Boston. Jeff has got master's degrees from Johns Hopkins and Harvard. He was a Boston school principal and as commissioner, successfully navigated Massachusetts schools through Covid and other crises. We talk about what the campaign is doing and how teachers are responding to it, risks of AI and social media to kids, what to do about cheating and AI detectors, and much more! All this plus our usual look at today's AI headlines. Transcript and URLs referenced at HumanCusp Blog.
Recording after the ball drops, Dr. Griffin and Vincent Racaniello wish everyone a Happy New Year, discuss an evidence-based approach to teaching and practice medicine and reminisce on the history of vaccine development and use before their discussion about the whooping cough outbreak of 2025 in the US and falling levels of tetanus vaccination, then Dr. Griffin then deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, how NY state reported the greatest number of influenza confirmed infections ever in one week during the week ending Dec 20, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Evidence-Based Medicine: A New Approach to Teaching the Practice of Medicine (JAMA) The US has seen nearly 28,000 whooping cough cases this year. Here's what you need to know (CNN) Vaccine History: Developments by Year (CHOP, Children's hospital of Philadelphia: Vaccine History) Reported Incidence of notable diseases in United States: 1952 Morbidity and Mortality Weekly Report, Vol. 1, No. 54, October 26, 1953 (CDC: Stacks) As tetanus vaccination rates decline, doctors worry about rising case numbers (nbc News) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) New York State Department of Health Confirms Most Flu Cases Ever Recorded in One Week: New York State Reports 71,123 Flu Cases This Week (NY State Department of Health) Weekly surveillance report: cliff notes (CDC FluView) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Nirsevimab vs RSVpreF Vaccine for Respiratory Syncytial Virus–Related Hospitalization in Newborns (JAMA) RSV Immunization Frequently Asked Questions(American Academy of Pediatrics) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Where to get pemgarda (Pemgarda) EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) UnderstandingCoverageOptions (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulationguidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Reaching out to US house representative Letters read on TWiV 1284 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.
Inside the Admissions Office: Advice from Former Admissions Officers
Want personalized help with your application strategy? Book a free 1:1 call with one of our Former Admissions Officers here: CLICK HERE. Shannon and Titania are back—this time tackling the Johns Hopkins supplemental essay. With Hopkins celebrating its 150th anniversary, this year's prompt sounds poetic, reflective, and… a little overwhelming. But what are admissions officers actually asking for? PART 1: How to answer Every Harvard Supplemental Essay Prompts! [WATCH IT HERE] PART 2: How to answer Yale Supplemental Essay + Short Answer Prompts! [WATCH IT HERE] --- Register for our upcoming webinars. We also offer tons of free resources on our website/blog. Questions, comments, or topic requests? Email jilian.yong@ingeniusprep.com. To learn more about InGenius Prep, visit us at ingeniusprep.com.
Calling out "Happy Christmas to all and to all a good-night, Dr. Griffin and Vincent Racaniello discuss high path influenza in dairy herds in Wisconsin and Marburg virus in Ethiopia before Dr. Griffin then deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the slightly higher association of COVID-19 infection with death than following influenza infection, benefit of passive infant immunization with niresevimab, association of COVID-19 vaccine immunogenicity protection against severe disease in vulnerable populations, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, effect of remdesivir and nirmatrelvir/ritonavir on COVID-19 associated mortality, where to go for answers to your long COVID questions, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode USDA Confirms Highly Pathogenic Avian Influenza in a Dairy Herd in Wisconsin (USDA Animal and Plant Health Inspection Service) Update: Genetic Sequencing Results for Wisconsin Dairy Herd Detection of Highly Pathogenic Avian Influenza(USDA Animal and Plant Health Inspection Service) Marburg Outbreak in Ethiopia: Current Situation (CDC: Marburg Virus Disease) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles(CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) USrespiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) In call with clinicians, CDC recommends flu vaccines widely(CIDRAP) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA) Increased 30-day Mortality Risk in Coronavirus Disease 2019 Compared to Seasonal Influenza (International Journal of Infectious Diseases) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Nirsevimab vs RSVpreF Vaccine for Respiratory Syncytial Virus–Related Hospitalization in Newborns (JAMA) RSV Immunization Frequently Asked Questions(American Academy of Pediatrics) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Association between COVID-19 vaccine immunogenicity and protection against infection and severe disease in clinically vulnerable patient populations: a systematic review and meta-analysis of observational studies (Clinical Microbiology and Infection) Where to get pemgarda (Pemgarda) EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) The effect of remdesivir and nirmatrelvir/ritonavir on mortality in patients hospitalized with COVID-19 during the Omicron era: an emulated target trial (Clinical Microbiology and Infection) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulationguidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Long-COVID research just got a big funding boost: will it find new treatments? (Nature) Reaching out to US house representative Letters read on TWiV 1282 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.
It's YOUR time to #EdUp with Dr. Anthony K. Wutoh, Provost, Howard UniversityIn this episode, sponsored by the ELIVE 2026 Conference in Denver, Colorado, April 19-22, & the 2026 InsightsEDU Conference in Fort Lauderdale, Florida, February 17-19,YOUR cohost is Megan Dusenbery, Chief Executive Officer, KnackYOUR host is Elvin FreytesHow does a provost increase graduation rates by over 20% & create programs like Karsh STEM Scholars & Humanities & Social Science Scholars that send students to PhD programs at Harvard, Stanford & Johns Hopkins?What happens when an HBCU partners with Google & Amazon Studios to create Tech Exchange & Howard Entertainment programs that give students real world experience in technology & the business of entertainment?How does a university leader with 30 years of experience think about AI's transformational impact on higher education while maintaining focus on ethics, access & preparing students for the world that's coming?Listen in to #EdUpThank YOU so much for tuning in. Join us on the next episode for YOUR time to EdUp!Connect with YOUR EdUp Team - Elvin Freytes & Dr. Joe Sallustio● Join YOUR EdUp community at The EdUp ExperienceWe make education YOUR business!P.S. Want to get early, ad-free access & exclusive leadership content to help support the show? Then subscribe today to lock in YOUR $5.99/m lifetime supporters rate! This offer ends December 31, 2025!
While we celebrate the remarkable achievement of 250 years of the US military being a bulwark of democracy, it is important to understand the intentionally laid foundations on which America's civil military relations tradition rests. Military deference to civilian authority and the legislature is a principle pioneered and championed by General George Washington, setting a powerful precedent for commanding officers to follow… with some instructive exceptions. As we look toward the New Year, and wearily at the political posturing of some military leaders, Kori Schake reminds us of a central theme from her new book, The State and the Soldier (Polity, 2025): “We want a military that's not partisan. We want a military that is subordinate to whatever lunatics the American public see fit to put into high office.” How are military leaders inherently political? How do we avoid forcing them to make partisan choices? And, as we have discussed all year, why does Congress refuse to exercise the powers it has, even in this realm?Kori Schake is a senior fellow and the Director of Foreign and Defense Policy studies at the American Enterprise Institute. Before joining AEI, Dr. Schake was the deputy director-general of the International Institute for Strategic Studies in London. She has had a distinguished career in government, working at the US State Department, the US Department of Defense, and the National Security Council at the White House. She was also senior policy advisor on the 2008 McCain campaign. She has taught at Stanford, West Point, Johns Hopkins, and the University of Maryland. Dr. Schake is the author of 5 books, with her newest titled “The State and the Soldier: A History of Civil-Military Relations in the United States.”Read the transcript here.Subscribe to our Substack here.Find The State and the Soldier here.
One of the two semifinals was a classic, fit for kids from 1 to 92 ... if you can handle stress, that is. And we aren't just spouting cliches when we say this is as good as it gets -- in the history of the national semifinals since automatic bids were added and the playoffs expanded beyond four rounds in 1999, there have been only two years where both semifinals were close. It's far more likely that both of them are two-score games! So to get not just one good one, but one epic one, well, that's great. When Kaleb Blaha threaded the tiniest hole to find Blake Rohrer, and Rohrer ran untouched to the end zone for a 79-yard touchdown against Johns Hopkins, it not only sent the Falcons to the Stagg Bowl for the first time ever, it united a community, and was another memorable moment in a friendship between the two. They talk about it, how they met, how Blaha recruited Rohrer to come out for the UW-River Falls football team, and how the River Falls community reacted on Saturday night, in Around the Nation. 2016 Around the Nation column: Out of darkness, light, by Adam Turer, featuring the rebuilding UW-River Falls program At North Central, the Cardinals got the best passing performance of the season from Garet Wilson, and Jack Rummell had some amazing catches and runs. What did Wilson say to him before a third-and-8 play, and how did Rummell respond? We also hear from transfer defensive end Eli Renick, and chat with coach Brad Spencer about what's next for North Central as they head to their sixth consecutive Stagg Bowl. Plus, for Johns Hopkins, what does this run ending mean for the state of the program? And for John Carroll, it's the end of two years where Nick Semptimphelter was able to play football for the Blue Streaks with tight end Terrence Rawls, who was not just his high school teammate, but a literal member of his family. He talks about that, and coach Jeff Behrman talks about Semptimphelter. Patrick and Greg also hand out game balls and we take your questions in the mailbag. That and more in this edition of the D3football.com Around the Nation podcast. The D3football.com Around the Nation podcast is a weekly conversation about NCAA Division III football, and has been running since 2007.
In his weekly clinical update, Dr. Griffin and Vincent Racaniello protest Vinjay Prasad, head of CBER FDA Nov memo stating administration of the COVID-19 vaccine resulted in 10 children's deaths, but are cautiously delighted by the December memo from those in CBER who dispute this data-less claim, how in 31 states pertussis vaccination rates have declined before Dr. Griffin then deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, of clinical outcomes of oseltamivir versus baloxavir for treating influenza infection, number deaths associated with COVID-19 hospitalizations and disease associated economic burden, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, how the German government is committed to research into long COVID and contacting your federal government representative to stop the assault on science and biomedical research. 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Links for this episode Industry laments Prasad vaccine memo (Politico) Scoop: FDA vaccine chief's memo cited 10 pediatric Covid-19 vaccine deaths—but the agency's own analysis found 0–7 (Inside Medicine) Whooping cough cases soar as vaccination rates drop (NBC News) Marburg Outbreak in Ethiopia: Current Situation (CDC: Marburg Virus Disease) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles(CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Hundreds quarantined as South Carolina measles outbreak accelerates (Washington Post) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) USrespiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) In call with clinicians, CDC recommends flu vaccines widely (CIDRAP) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA) Comparison of clinical outcomes of oseltamivir versus baloxavir in outpatients with influenza: a retrospective cohort analysis (International Journal of Infectious Diseases) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Effectiveness of 2024–2025 COVID-19 Vaccines in Children in the United States — VISION, August 29, 2024–September 2, 2025 (CDC:MMWR) Mortality following recovery from COVID-19 hospitalization: A long-term cohort study (International Journal of Infectious Diseases) COVID hospitalization tied to 69% higher risk of death for up to 2 years (CIDRAP) Where to get pemgarda (Pemgarda) EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Comparison of work productivity losses in the United States among employees with COVID-19 at high-risk of severe disease who were untreated or treated with nirmatrelvir/ritonavir (Journal of Medical Economics) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulationguidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Long-COVID research just got a big funding boost: will it find new treatments?(Nature) Reaching out to US house representative Letters read on TWiV 1280 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.
Send us a textWhat if the most powerful tool on a crisis scene isn't a badge or a diagnosis, but a practiced partnership? We continue our conversation with Dr. Sarah Abbott about co-response and unpack how pairing clinicians with police changes the outcome of calls involving mental health, substance use, and high-stress events—from domestic incidents with kids present to house fires and welfare checks where information is thin.We trace the arc from a pioneering certificate at William James College to statewide intensives built on scenario-based, hands-on training. Instead of chasing labels, the curriculum teaches behavior reading, de-escalation under pressure, and language that preserves dignity while lowering risk. We dig into veterans' mental health and firearm culture, highlighting lethal means safety training that helps clinicians speak credibly about storage, temporary transfer, and time-limited access without shaming or seizing. A vivid field story shows how clear communication with dispatch and officers can soften the room, protect everyone on scene, and build trust that lasts past one call.The conversation widens to where co-response goes next. Through Abbott Solutions for Justice and the International Co-Responder Alliance, these practices are spreading across states and overseas, with growing momentum on college campuses that function like small cities. We explore why campus police and clinicians need shared playbooks, how programs like Johns Hopkins are leading, and what it takes to turn skepticism into skill—consistently, respectfully, and at scale. If you care about first responder wellness, community safety, and practical tools that work at 2 a.m., this is your roadmap for doing crisis response better.Subscribe for more conversations on co-response, first responder mental health, and practical de-escalation. Share this episode with a colleague who needs these tools, and leave a quick review to help others find the show.To reach Sarah, please visit her website at: https://www.abbottsolutionsforjustice.comSarah can also befound on LinkedIn at: https://www.linkedin.com/company/abbott-solutions-for-justice-llc/?viewAsMember=trueFreed.ai: We'll Do Your SOAP Notes!Freed AI converts conversations into SOAP note.Use code Steve50 for $50 off the 1st month!Disclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showYouTube Channel For The Podcast
In this episode Bill interviews Dr. John Gartner, a former Johns Hopkins professor and founder of Duty to Warn. In his return to the Bill Press Pod, Dr. Gartner provides an in-depth analysis of President Donald Trump's cognitive health, asserting that Trump exhibits signs of severe cognitive decline and personality disorders such as malignant narcissism. He discusses specific instances that showcase Trump's deteriorating mental state, including erratic behavior, memory lapses, and lack of empathy. The episode delves into the challenges and dangers posed by Trump's mental condition, its implications on his presidency, and potential future scenarios.Today Bill once again highlights the work of Chef Jose Andres' World Central Kitchen. While the Trump administration is decimating America's soft power around the world, and our role as a provider of aid to people and countries in peril, the World Central Kitchen goes where they're needed. No matter the war zone nor the danger of a natural disaster. This is one of Carol and my favorite charities and I hope you'll support them at WCK.orgSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.