Podcasts about Genetics

Vagus Nerve Stimulation Improves Cognitive Scores in a Small Trial In a 24-week trial involving people with mild cognitive impairment, participants assigned to electrical stimulation at vagus-innervated parts of the ear improved by an average of 3.2 points on a general cognitive test, compared with 0.3 points in a sham-stimulation group. Host Dave Asprey explores the proposed connection between the vagus nerve and the locus coeruleus, a brainstem region involved in attention and learning. He explains why an improved test score is intriguing but does not show that vagus nerve stimulation prevents Alzheimer's disease—or that a consumer device will reproduce the study's results.pubmed.ncbi.nlm.nih+1 Sources: https://pubmed.ncbi.nlm.nih.gov/36150665/ https://pmc.ncbi.nlm.nih.gov/articles/PMC13214873/ https://theconversation.com/vagus-nerve-stimulation-shows-promise-as-a-way-to-counter-alzheimers-disease-and-age-related-memory-loss-269465 ~~~Nearly 500 Cat Tumors Reveal Cancer Genes Shared With Humans Researchers analyzed 493 matched tumor and normal-tissue samples across 13 types of cancer in domestic cats. They found alterations in genes familiar to human cancer researchers, including TP53, and tested whether a mutation called FBXW7 might predict drug sensitivity in lab-grown models of feline mammary tumors. Host Dave Asprey examines why naturally occurring cancers in pets could help scientists investigate treatments across species, while making clear that a promising response in six laboratory tumor models is not a proven treatment for cats or people.pmc.ncbi.nlm.nih Sources: https://pmc.ncbi.nlm.nih.gov/articles/PMC7618901/ https://pubmed.ncbi.nlm.nih.gov/41712721/ https://www.sciencedaily.com/releases/2026/09/260924231826.htm ~~~Twin-Family Study Challenges a Simple Explanation for Inherited Intelligence Why do parents and children often score similarly on tests of cognitive ability? Researchers using Germany's TwinLife data found that genetic transmission explained more of that resemblance than the particular shared-home-environment pathway their model tested. Host Dave Asprey unpacks the distinction between why relatives resemble one another and whether a child's environment matters. The study does not show that parenting, education, or other experiences have no effect on cognition.pub.uni-bielefeld+1 Sources: https://pub.uni-bielefeld.de/record/2993432 https://www.psypost.org/genetics-not-shared-environments-drives-parent-child-similarities-in-cognitive-ability/ ~~~Mulberry Compounds May Change Gut Bacteria and Metabolism A review of mulberry research highlights how leaves, fruit, and differently processed extracts contain distinct mixtures of compounds that gut microbes may use. In mouse experiments, a fraction combining mulberry polyphenols and polysaccharides produced more favorable microbiome and metabolic changes than either fraction alone; transferring microbes from treated mice passed along some of those effects. Host Dave Asprey explores the idea that a plant extract's preparation may matter as much as its name—and why the findings do not yet establish a microbiome benefit from mulberry products in humans.pmc.ncbi.nlm.nih+1 Sources: https://pmc.ncbi.nlm.nih.gov/articles/PMC13406227/ https://www.sciencedaily.com/releases/2026/09/260928100551.htm ~~~Magnesium Changes Vitamin D Metabolism—But Not Always in the Same Direction Magnesium helps regulate the pathways that process vitamin D, but “more magnesium means more vitamin D” is too simple. In a 12-week randomized trial involving 180 adults, magnesium supplementation changed a measured vitamin D metabolite differently depending on participants' starting vitamin D levels: the modeled difference was positive at 30 ng/mL and negative at 50 ng/mL. Host Dave Asprey explains why this matters to people tracking supplement stacks and bloodwork, while distinguishing a change in a lab marker from a demonstrated health benefit.pubmed.ncbi.nlm.nih+1 Sources: https://pmc.ncbi.nlm.nih.gov/articles/PMC6693398/ https://pubmed.ncbi.nlm.nih.gov/29480918/ https://www.sciencedaily.com/releases/2018/02/180226122548.htm This episode is designed for biohackers, longevity enthusiasts, pet owners, parents, and anyone trying to separate a compelling biological mechanism from a proven health intervention. Host Dave Asprey examines brain stimulation and memory, what cat cancers could teach human researchers, how genes and environment contribute to cognitive similarity, whether mulberry's microbiome effects translate beyond mice, and why nutrient interactions are rarely as simple as a supplement headline suggests. Several studies discussed here predate this week's coverage; this is a research roundup, not a list of five newly published trials.pmc.ncbi.nlm.nih+4 New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: vagus nerve stimulation memory, auricular vagus nerve stimulation, mild cognitive impairment, Alzheimer's research, locus coeruleus, cat cancer genetics, feline oncogenome, FBXW7 feline mammary cancer, comparative oncology, parent child cognitive ability, TwinLife cognitive ability study, intelligence genetics, shared environment cognition, mulberry gut microbiome, mulberry polyphenols polysaccharides, microbiota transfer mice, magnesium vitamin D metabolism, magnesium supplementation vitamin D, biohacking research roundup Thank you to our sponsors! - Butcher Box | Go to ButcherBox.com/HUMANUPGRADE to get $20 off your first box, plus your choice of free ground beef for life, or free chicken thigh - Beyond Wonderland Conference | Oct 13 - 14, 2026. Get your ticket now at wonderlandconference.com. - The One Device | Use code DAVE for $10 off at theonedevice.com/dave - iRestore | Unlock your best hair & skin with @iRestorelaser and HUGE savings on iRESTORE with code DAVE at irestore.com/DAVE Resources: • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 — Intro 00:18 — Vagus Nerve 01:51 — Cat Cancer 03:53 — Genetics & Parenting 05:46 — Mulberries 07:43 — Magnesium & Vitamin D 09:25 — Takeaway See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Welcome back to today's Friday Review where I'll be breaking down the best of the week!     I'll be sharing specifics on these topics:     Green Banana Flour (product review) Genetics vs. Environment (tip of the week) Prostate Cancer & Pharmaceuticals (research) Soil Bacteria & Serotonin (research)     For all the details tune in to today's Cabral Concept 3892 – Enjoy the show and let me know what you thought!   - - For Everything Mentioned In Today's Show: StephenCabral.com/3892 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

What if we could make gasoline from air? We explore how carbon dioxide, water, and electricity can become synthetic gasoline, jet fuel, rocket propellant, plastics, and more.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurCheckout Space Money and our Space Industry Collection: https://nebula.tv/isaacarthur/space-industry-collection

What happens when gut health, menopause, peptides, nutrition, and food policy all start converging? After seven years of conversations about the future of wellness, the trends are pointing toward a bigger shift: new tools may change how we approach healthspan, and yet the fundamentals still matter.Host Jenn Trepeck closes out The Next Frontier Files, the seven-episode miniseries retrospective from Salad With a Side of Fries as she reflects on year seven. She shares her own take on the next frontier in wellness, and explains how peptides and food policy fit into the future of healthspan. It is a big-picture reminder that the basics still matter most, no matter which new trend arrives next.What You Will Learn in This Episode:✅ Why convergence is the defining theme of year seven, with gut health, menopause, and peptides appearing together like never before.✅ How the GLP-1 boom is pushing fiber and micronutrients into the spotlight, and why muscle wasting is a risk of eating too little.✅ Which foundations, from nutrition and sleep to community, protect your healthspan when new biohacking tools arrive.✅ How a proposed reckoning with the food supply and processed foods could make quality nutrition more affordable.The Salad With a Side of Fries podcast, hosted by Jenn Trepeck, explores real-life wellness and weight-loss topics, debunking myths, misinformation, and flawed science surrounding nutrition and the food industry. Let's dive into real-life wellness and weight loss, including drinking, eating out, and skipping the grocery store.TIMESTAMPS:00:00 Welcome to the year seven finale and a look at how wellness trends all converge at once04:15 Philip Pape begins year seven recap with precision medicine, genetics, and artificial intelligence joining forces07:19 Abby Sharp warns against the pathologizing of hunger and our bond with food11:51 Jared St. Clair discusses why gut health and microbiota transplant may explain more than digestion, including mental health13:06 Dr. Stan Pierce shares his perspective on Neuralink, brain-computer interfaces, and new funding for brain research that could change healthcare16:06 Hormones, menopause, thyroid, and peptides as five voices reach beyond their own topics19:14 Sarah Wragge predicts Fiber and micronutrients will take center stage as GLP-1 users risk bone density and muscle loss20:14 Dr. Diane Mueller discusses why aging gets blamed too often, and how community, connection, and cortisol shape healthspan24:38 Dr. Eric Osansky discusses the relationship between cortisol and stress management26:01 Molly McNamee says let's get back to basics: why foundations of health never go out of style as new trends keep cycling26:38 Jenn pulls together all the predictions as well as her own thoughts for the next frontier in wellnessKEY TAKEAWAYS:

APR Health Solutions Peptides: www.aprhealthsolutions.com - code nyleOptimize HRT Clinic: https://members.optimize-hp.com - code nyleMerch: https://www.aykons.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story  https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'nyle' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘nyle' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program:  https://www.nylenaygafitness.com00:00 Intro01:38 Modern Harm Reduction vs. Forum Bro-Science04:39 Estrogen, Growth Hormone, and the IGF-1 Myth09:59 The Real Drivers of Bodybuilder Mortality13:20 The Death of the Trenbolone Megadose16:58 Old-School Venice Roots & Tier List Setup18:32 Trestolone (MENT) & Blood-Brain Barrier Transport26:01 Guarding the Brain: Memantine & Neuroprotection28:55 Frank Zane, Vacuums, and Core Aesthetics31:21 Testosterone (The S-Tier Anchor)34:12 Masteron Mechanics & Studio Crash37:16 Trenbolone (B-Tier Reality & Sleep)44:39 Masteron (B-Tier Cosmetic Polisher)49:17 Primobolan (A-Tier Secondary King)52:54 Nandrolone (D-Tier Progestogenic Trap)57:37 Clinical Ancillaries & Organ Health Sponsor59:41 Boldenone (D-Tier E2 Crashes & Hematocrit)01:05:47 Horse Estrogen, Premarin, and Ketamine Memes01:08:18 Genetics of Aromatization: High vs. Low Converters01:10:29 DHB (F-Tier Systemic Inflammation)01:19:23 Trestolone (D-Tier Autonomic Strain)01:26:08 Winstrol (A-Tier Pre-Contest Finisher)01:31:39 Dianabol (F-Tier Golden Era Relic)01:35:28 Halotestin (C-Tier Pure Central Drive)01:43:32 Proviron (C-Tier Androgenic Support)01:48:27 Superdrol & Anadrol (C & D-Tier Mass Loaders)01:52:46 Methyltrienolone & Liver Limits01:54:16 Crushing Cardiovascular Risk: ApoB & Ezetimibe01:56:07 Protecting the Kidneys: Telmisartan & Blood Flow01:57:41 The Dangerous Trap of Frequent Blood Donation02:01:07 Stopping Heart Hypertrophy: Eplerenone Protocols02:03:12 Kidney Health Ancillaries: Pentoxifylline & SS-3102:07:44 Dialing in Estrogen on Trenbolone02:11:37 Tren Acetate vs. Tren Enanthate Kinetics02:13:13 Preventing Steroid-Induced Facial Aging02:18:18 How to Design an Intelligent First Cycle02:22:11 Can Anything Truly Replace Trenbolone?02:26:01 Case Study: Client 'Run This' Biomarker Mastery02:27:13 Rebuilding the Gut After Heavy Oral Cycles02:29:03 Closing Thoughts: Longevity, Perspective, and Wrap-Up

Menopause Mastery | Glutathione, Menopause, & Aging: The Missing Piece in Oxidative Stress and Why It Matters  | Ep. 298 with Dr. Gina Nick  

How can we explain vivid, life changing experiences and true perceptions occurring in patients between brain death and resuscitation? What are the implications of true information being anomalously communicated during these experiences? What are the implications of some children being able to access the memories of deceased people? Why do such a high portion of these kids remember a traumatic death?In this episode we have the two fascinating phenomena of near death experiences, and access to deceased peoples memories to look into. So, we discuss the history of NDE research, the main repeating components of the experiences and some of the anomalous information received; we talk about the radical changes in meaning, purpose and world views after such experiences; and the difficulties integrating this with their previous daily lives and relationships. Then we switch and look at the research into children who appear to have memories of people who are no longer alive, and the attempts to identify the dead person and verify if these things actually happened to them. And of course we're going to look at the implications of these anomalous phenomena for life, death, consciousness and the nature of reality.Our guest today is a psychiatrist and neuro-behavioural scientist in the Division of Perceptual Studies at the University of Virginia, Marieta Pehlivanova. She's the author of 12 scientific papers, many co-authored with Dr. Bruce Greyson, the founder of the International Association for the Study of Near Death experience, who recommended Marieta in his stead now he is unable to give interviews any more. Please feel free to donate to the Division of Perceptual StudiesDonation · University of Virginia · GiveCampusGetting funding to study anomalous phenomena is harder than ever, and we don't want this research to drop off the map.What we discuss: 00:00 Intro.06:45 Near Death Experiences.06:25 The Dept Of Perceptual Studies (DOPS), UOVirginia.14:15 Near Death Experience Scale: Features of NDE in psychiatry.18:15 Not everyone has the life review.19:30 Anomalous features. 26:20 The new Near Death Experience Contents Scale.28:20 NDE is hard to put into words.31:20 Mental health and integration support for NDErs.39:20 Metaphysical implications of NDEs.43:00 The afterlife hypothesis.44:00 The prejudice caused by our experience of the arrow of time.46:00 NDErs say, “everything is happening at the same time”.49:25 Children who have dead peoples memories, reincarnation-like cases - Ian Stevenson & Jim Tucker.52:30 How the accuracy of the memory is investigated.55:31 Habitual or biological similarities between child and remembered person.56:00 Resistance in jumping to the reincarnation hypothesis.58:30 %60 of the kids recall a traumatic death, some have trauma symptoms01:02:00 Comparing brain scans of these apparently traumatised children.01:04:45 New research coming on autobiographic memory pathways.01:07:30 Epigenetic and genetic approaches.01:07:50 Potential to explain intergenerational trauma mechanism.01:10:45 Metaphysical implications of children's memories of dead adults.01:15:30 Assessing claims that those who accept psi lack critical cognitive ability.References:International Association for Near-Death Studies (IANDS)Greyson's Near-Death experience scaleCharlotte Martial et al. 2020. 'The Near-Death Experience Content (NDE-C) scale'.Bruce Greyson, ‘Seeing Dead People Not Known to Have Died: “Peak in Darien' Experiences'.Pehilvanova, M. ‘Support needs after a near-death experience: A quantitative study with experiencers'.Sadeghi, S. Et al. ‘A large-scale analysis of temporal patterns in children's purported past-life memories: Shorter intervals following unexpected deaths'Helené Wahbeh et al. ‘Genetics of Psychic ability - A pilot case-control exam sequencing study'Marieta Pehilvanova, ‘Cognitive styles and psi: psi researchers are more similar to skeptics than to lay believers' 

Menopause Mastery | Glutathione, Menopause, & Aging: The Missing Piece in Oxidative Stress and Why It Matters  | Ep. 298 with Dr. Gina Nick  

When a family of 9 siblings noticed their mother acting strangely, they chalked it up to depression and alcoholism. But after some of the siblings began to exhibit the same behavior, the family learns that they are carriers of a rare gene mutation that causes frontotemporal dementia, and have a 50/50 chance of inheriting the same condition and passing it on to their kids. Journalist and author Robert Kolker tells the story of this family in his new book, The Vanishing Family: Love, Fate, and the Quest to End Dementia.Alex Strada is the inaugural Public Artist in Residence with the NYC Department of Homeless Services and the NYC Department of Cultural Affairs. In that role, Strada created a project called Public Address, in which she engaged with New Yorkers living in the shelter system to create logs that compiled their testimony and expression. Some of that testimony has now been created into signs, designed by the Department of Transportation, that have been on view throughout the city in 2026. The installation is now on view at Joyce Kilmer Park in the Bronx, and other components of the projects will be on view at the Bronx Museum on October 9. Strada discusses her role as an artist in city government, and the idea behind the Public Address project.Image courtesy of the artist Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Histamine and MCAS are everywhere on the internet right now, but there's a huge piece missing from the conversation. Genetics. In this episode, I’m joined by two board-certified genetic counselors, Natalie Samson and Sarah Upp of Golden Genetics. They're here to break down what’s going on at a DNA level when it comes to histamine intolerance, MCAS, connective tissue disorders, and the symptoms so many vestibular warriors are navigating. The biggest takeaway might just be how you can start advocating for yourself with your providers (especially if these things are new to them). This one is dense, practical, and unlike any conversation I’ve had on this podcast before. In this episode, we'll dig into: How genetic changes affect how your body works How your environment and genetics work together The pentad super syndrome Why weak connective tissue may be at the root of these overlapping conditions What happens when the DAO and HMT genes aren’t working well Where histamine comes from and how to empty it The barn analogy for understanding mast cell stabilization Why a low histamine diet isn’t meant to be forever Foods to add in that lower histamine The two panels Golden Genetics recommends Why methylation matters for histamine breakdown What to do when testing for MCAS doesn't give clear answers How to advocate for yourself when a provider dismisses MCAS as a social media diagnosis The ongoing research between Golden Genetics and the vestibular migraine community How to use the 2026 MCAS guidelines flowchart at your next appointment Histamine intolerance and MCAS aren’t just about what you’re eating.  They’re rooted in your genetics, and understanding your specific DNA can help you stop guessing and start identifying the right interventions for your body. Related Episodes: Toxic Products That May Be Making Your Dizziness Worse w/ Dr. Zach Spiritos: https://thevertigodoctor.com/podcast/53-toxic-products-that-may-be-making-your-dizziness-worse/   Meet Natalie Samson & Sarah Upp Natalie Samson and Sarah Upp are both board-certified genetic counselors and the team behind Golden Genetics, an integrative genetic counseling practice. They specialize in helping people understand their DNA, order the right tests and turn results into a personalized action plan—with a special focus on histamine, inflammation, connective tissue, and nutrigenomics.  Natalie founded Golden Genetics to bring genetics into the integrative health conversation, and together she and Sarah are currently conducting research on the genetic links to vestibular migraine. Connect w/ Natalie Samson & Sarah Upp: Website: www.goldengeneticshealth.com  What is a logistics call with Golden Genetics? https://goldengenetics.practicebetter.io/#/652843bfc5600d631946d7b9/bookings?r=67d88822ff4b8cf37956c65d&step=services Book a logistics call with Golden Genetics: https://www.goldengeneticshealth.com/book-a-discovery-call-1 Pre-test session with Sarah: https://goldengenetics.practicebetter.io/#/687574970c2232e0dccceef5/bookings?r=69bb16570d392e7826c8903b Instagram: https://www.instagram.com/goldengeneticshealth  Links Mentioned: Vestibular Group Fit (code GROUNDED at checkout for 15% off!): https://thevertigodoctor.com/vestibular-group-fit 2026 MCAS Guidelines flowchart: https://www.mastcellaction.org/assets/_/2025/04/01/d6de24e1-f6f6-4248-a3f4-12866d7bf713/mast-cell-activation-syndrome-mcas-a-primary-care-guide-final.pdf Free Resources: ⁠The 4 Steps to Managing Vestibular Migraine: https://thevertigodoctor.myflodesk.com/cb5js0y78n ⁠The PPPD Management Masterclass⁠: https://thevertigodoctor.myflodesk.com/new-pppd ⁠What your Partner Should Know About Living with Dizziness⁠: https://thevertigodoctor.myflodesk.com/partnership ⁠The FREE Mini VGFit Workout⁠: https://thevertigodoctor.myflodesk.com/minifit ⁠The FREE POTS – safe Workouts⁠: https://thevertigodoctor.myflodesk.com/pots Connect with Dr. Madison (@TheVertigoDoctor): https://instagram.com/thevertigodoctor Work with Dr. Madison: For 1:1 Vestibular Rehabilitation Therapy, email madison@thevertigodoctor.com Otherwise, I'll see ya in Vestibular Group Fit! Connect with Dr. Jenna (@dizzy.rehab.therapist): https://www.instagram.com/dizzy.rehab.therapist/ Learn about the Oak Method: http://thevertigodoctor.com/why-vestibular-group-fit Love what you heard?Consider leaving a review on your favorite podcast platform to help us reach more vestibular warriors like you! This podcast is for informational purposes only and may not be the best fit for you and your personal situation. It shall not be construed as medical advice. The information and education provided here is not intended or implied to supplement or replace professional medical treatment, advice, and/or diagnosis. Always check with your own physician or medical professional before trying or implementing any information read here. is histamine intolerance genetic, genetics and mcas, genetics and histamine, genetic counselors, vestibular migraine, VM, chronic dizziness, PPPD, nervous system regulation, migraine management, vestibular group fit, VGF

We've always said the same thing at Purser Wellness: you can't really understand what's going on by looking at just one piece of the puzzle.That's why we look at your genetics, your intracellular nutrient levels, and your hormones together. Genetics can show us what you may be predisposed to, intracellular testing tells us what's actually happening at the cellular level, and hormone testing helps us see another major part of how you're feeling and functioning.Now, through our partnership with Eleva MD, we can add physician-supervised telemedicine hormone replacement therapy to that approach.The Eleva MD team has been trained in Purser Protocols for hormone replacement therapy, so our patients can get convenient hormone care from home while still following the approach we've developed over the years.Genetics. Nutrients. Hormones. Put them together, and you get a much clearer picture.Learn more at purserwellness.eleva.md.

Can you actually extend your life without sacrificing your quality of life? Ethan sits down with Dr. Florence Comite, a pioneering physician in precision medicine and longevity, to explore what really drives healthy aging. They discuss metabolic health, genetics, hormones, biomarkers, muscle, diabetes, GLP-1 medications, and why individual health data matters more than one-size-fits-all advice. Ethan also shares his own journey of losing 300 pounds, navigating different diets, and learning how to maintain his weight. Dr. Comite explains why understanding your personal biology can help you make better decisions about your health and future.Subscribe to Ethan's newsletter:https://ethansuplee.substack.com/subscribeSHOW HIGHLIGHTS00:00 - What Does Longevity Really Mean?03:00 - Living Longer vs. Living Better06:00 - Why Diets Don't Work for Everyone09:00 - Genetics, Biomarkers and Small Habits12:00 - Women's Hormones and Menopause15:00 - Testosterone, Aging and Men's Health18:00 - Why GLP-1 Medications Matter21:00 - GLP-1s and the Future of Metabolic Health24:00 - Understanding Blood Sugar and A1C27:00 - Managing Type 1 Diabetes30:00 - The Limits of Modern Medicine33:00 - How Ethan Lost 300 Pounds36:00 - Weight Loss, Maintenance and Diet Breaks39:00 - Testosterone, Muscle and Five Key Biomarkers42:00 - When Dieting Goes Too Far45:00 - Should Everyone Take a GLP-1?48:00 - Exercise, Addiction and Finding Balance Hosted on Acast. See acast.com/privacy for more information.

What if we could make gasoline from air? We explore how carbon dioxide, water, and electricity can become synthetic gasoline, jet fuel, rocket propellant, plastics, and more.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurCheckout Space Money and our Space Industry Collection: https://nebula.tv/isaacarthur/space-industry-collection

******Support the channel******Patreon: https://www.patreon.com/thedissenterPayPal: paypal.me/thedissenterPayPal Subscription 1 Dollar: https://tinyurl.com/yb3acuuyPayPal Subscription 3 Dollars: https://tinyurl.com/ybn6bg9lPayPal Subscription 5 Dollars: https://tinyurl.com/ycmr9gpzPayPal Subscription 10 Dollars: https://tinyurl.com/y9r3fc9mPayPal Subscription 20 Dollars: https://tinyurl.com/y95uvkao ******Follow me on******Website: https://www.thedissenter.net/The Dissenter Goodreads list: https://shorturl.at/7BMoBFacebook: https://www.facebook.com/thedissenteryt/Twitter: https://x.com/TheDissenterYT This show is sponsored by Enlites, Learning & Development done differently. Check the website here: http://enlites.com/ Dr. Kevin Mitchell is Associate Professor of Genetics and Neuroscience at Trinity College Dublin. He is interested in the development of connectivity in the brain, specifically in how this process is controlled by genes and how mutations in such genes affect the connectivity of neuronal circuits, influence behavior and perception and contribute to disease. His latest book is Free Agents: How Evolution Gave Us Free Will. In this episode, we talk about the study of individual differences in psychological traits. We start by discussing what they are. We talk about process ontology and dynamical systems theory. We discuss animal models and ecology. We talk about what we can learn from behavioral genetics, the concept of heritability, and the role of the environment and gene-environment correlations. We discuss misconceptions people have about group differences. We talk about the role of randomness in development and psychology. Finally, we discuss why some behavioral scientists aredeterminists.--A HUGE THANK YOU TO MY PATRONS/SUPPORTERS: PER HELGE LARSEN, ADAM KESSEL, MATTHEW WHITINGBIRD, ARNAUD WOLFF, TIM HOLLOSY, HENRIK AHLENIUS, ROBERT WINDHAGER, RUI INACIO, ZOOP, MARCO NEVES, COLIN HOLBROOK, PHIL KAVANAGH, SAMUEL ANDREEFF, FRANCIS FORDE, TIAGO NUNES, FERGAL CUSSEN, HAL HERZOG, NUNO MACHADO, JONATHAN LEIBRANT, JOÃO LINHARES, STANTON T, SAMUEL CORREA, ERIK HAINES, MARK SMITH, JOÃO EIRA, TOM HUMMEL, SARDUS FRANCE, DAVID SLOAN WILSON, YACILA DEZA-ARAUJO, ROMAIN ROCH, YANICK PUNTER, CHARLOTTE BLEASE, NICOLE BARBARO, PAWEL OSTASZEWSKI, NELLEKE BAK, GUY MADISON, GARY G HELLMANN, SAIMA AFZAL, ADRIAN JAEGGI, JOÃO BARBOSA, JULIAN PRICE, HEDIN BRØNNER, FRANCA BORTOLOTTI, URSULA LITZCKE, SCOTT, ZACHARY FISH, TIM DUFFY, SUNNY SMITH, JON WISMAN, WILLIAM BUCKNER, GEORGIOS THEOPHANOUS, CHRIS WILLIAMSON, PETER WOLOSZYN, DAVID WILLIAMS, DIOGO COSTA, ALEX CHAU, CORALIE CHEVALLIER, BANGALORE ATHEISTS, LARRY D. LEE JR., DAN SPERBER, ROBERT GRESSIS, JEFF MCMAHAN, JAKE ZUEHL, MARK CAMPBELL, TOMAS DAUBNER, LUKE NISSEN, KIMBERLY JOHNSON, JESSICA NOWICKI, LINDA BRANDIN, VALENTIN STEINMANN, ALEXANDER HUBBARD, BR, JONAS HERTNER, URSULA GOODENOUGH, DAVID PINSOF, SEAN NELSON, MIKE LAVIGNE, JOS KNECHT, LUCY, MANVIR SINGH, PETRA WEIMANN, CAROLA FEEST, MAURO JÚNIOR, TONY BARRETT, NIKOLAI VISHNEVSKY, STEVEN GANGESTAD, TED FARRIS, HUGO B., JORDAN MANSFIELD, CHARLOTTE ALLEN, DAVID TONNER, PATRICK DALTON-HOLMES, NICK KRASNEY, RACHEL ZAK, DENNIS XAVIER, CHINMAYA BHAT, RHYS, ALEX MACLEOD, HAIDAR, JULIEN PORCHER, JON STEWART, JAMES DORLING, JULIEN PORCHER, 航 豊川, ED MAKLOUF, LUIZ PESSOA, AND DAVID COOPER!A SPECIAL THANKS TO MY PRODUCERS, YZAR WEHBE, JIM FRANK, ŁUKASZ STAFINIAK, TOM VANEGDOM, BERNARD HUGUENEY, CURTIS DIXON, THOMAS TRUMBLE, KATHRINE AND PATRICK TOBIN, JONCARLO MONTENEGRO, NICK GOLDEN, CHRISTINE GLASS, IGOR NIKIFOROVSKI, PER KRAULIS, ADAM HUNT, AND JOÃO BARBOSA!AND TO MY EXECUTIVE PRODUCERS, MATTHEW LAVENDER,SERGIU CODREANU, AND GREGORY HASTINGS!

What happens when time stops being scarce? From nanobots to mind uploads, we explore the economy of immortality... and what it costs to live forever.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurCheckout Mad Kings : https://nebula.tv/madkings?ref=isaacarthur

What happens when time stops being scarce? From nanobots to mind uploads, we explore the economy of immortality... and what it costs to live forever.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurCheckout Mad Kings : https://nebula.tv/madkings?ref=isaacarthur

Thank you for watching!~CHECK OUT ALL THE LINKS BELOW FOR THE SYNDICATE & RIOT Co.!https://link.me/breederssyndicate~SUPPORT the channel or JOIN the Discord community: https://www.buymeacoffee.com/matthewriot (This channel is not monetized - any contributions are warmly appreciated & keep us going)~Links For Dr. Rick's CHS Survey (PLEASE DO THIS IF YOU ARE EXPERIENCING NAUSEA AND SMOKING!) https://www.belly-md.com/riot~QUALITY GEAR (shirts, stickers, beanies, mugs etc): https://breeders-syndicate-shop.fourthwall.com~PLANT HEALTH & SEX TESTING: https://www.farmerfreeman.com  (Coupon Code: SYNDICATE5 )

Doctor Asa is America's Health Coach and Trusted Voice on Longevity and Human Potential.   Get Your FREE Dr. Asa Best-Selling Book at: https://www.MyFreeHealthBook.com   Join Our VIP Health Community https://www.drasa.com/vip   Visit Us At Our VIP Health Retreats https://www.drasa.com/retreats/   Visit Our Local Providers https://www.drasa.com/find-a-provider/   Become motivated and reach the best version of you by listening to The Dr. Asa Show created by Dr. Asa Andrew, MD, DC, ND, is one of the worlds only 3-doctorate physicians yielding a unique perspective between traditional medical and natural-based health information is board-certified in clinical nutrition.   Doctor Asa, or Dr. Asa, a fitness enthusiast who hasn't missed a day of exercise since he started at age 17, teaches on performance and longevity, founder of the largest health-focused television, radio, and digital network, #1 sought after speaker, best-selling author, Reality TV producer, CEO, entrepreneur, and creator of the largest multi-platform health media company with a 35+ million potential reach, which hosts the #1 Ranked 3-hour syndicated daily health talk show. On his daily radio and television programs, The Dr. Asa Show, Dr. Asa Andrew answers questions on subjects like longevity, human potential, health, personalized nutrition, fitness, medicine, lifestyle, psychology, and you will find a blend of the radio show, special celebrity interviews, #AskDrAsa, Q&A, keynote speeches, Reality TV, and the overall journey.   Oh and Doctor Asa is also The Ringside Physician and Top Heal of Professional Wrestling with TNA Wrestling and partnership with WWE and still competes in the ring.   Have a Question? Call Me 1-888-283-7272 Text Me 1-407-255-7076 DM Me  @DrAsa Email Me  Ask@DrAsa.com

Guests:Dr. Luke Rendell, Biologist at Sean Mammal Research Unit in the University of St. AndrewsMatthew Campbell, Professor of Genetics at TCDCiara Greene, Associate Professor in the School of Psychology, UCD

LL LIVE Ep. 210Join us for another LL LIVE open discussion, where patients and future patients can ask questions, share updates, and talk about limb lengthening recovery, surgery, rehab, and everything in between.Drop your questions in the live chat and join the conversation._____________________Timestamps - **LL LIVE #210 — Dr. Michael Assayag + Dr. Franz Birkholtz Live Q&A**0:00 – Intro1:28 – Dr. A on PRECICE Max Early Results and Clinic Updates 5:38 – Dr. Birkholtz'sUpdates 7:23 – Live Q&A 7:54 – Osteomyelitis Risk After Internal LL 10:02 – Dental Work, Implants, and Infection Concerns w/ LL 10:40 – Prior ACL Reconstruction and Femur Lengthening 11:41 – PMAX Availability in the U.S. vs. South Africa 14:33 – 5 cm Tibia vs. Femur Lengthening: Risk and Recovery 17:21 – Can Tibia Lengthening Safely Go Beyond 5 cm? 19:12 – Flat Foot, Equinus, and Soft-Tissue Compensation During Tibia Lengthening 22:16 – Staged Quadrilateral Lengthening and Retrograde Femur Concerns 24:38 – What Comes After PMAX? Smart Nails and Future Technology 27:17 – Biologics, Peptides, Bone Regenerate, and Future Healing Research 30:13 – Genetics, Fat Embolism Risk, and Better Patient Screening 33:02 – Humerus Lengthening, External Fixators, and Scarring 35:16 – Should Patients Tell Family and Friends About Limb Lengthening? 39:50 – Should You Tell a Future Partner About the Surgery? 40:49 – PMAX Femurs + External Fixator Tibias to Save Money? 45:21 – MRI Safety with PRECICE Nails 47:20 – Nail Removal, Muscle Scarring, and Reusing Old Incisions 50:02 – Can You Go From 5'6 to 6'0 With Limb Lengthening? 52:00 – Why Extreme Height Goals Can Lead to Long-Term Problems 55:48 – One Leg at a Time vs. Bilateral Quadrilateral Lengthening 59:10 – Staying Awake During Surgery vs. General Anesthesia 1:01:05 – Returning to Skiing, Running, Basketball, and High-Impact Sports 1:04:27 – How Long Until You Are Fully Recovered? 1:05:02 – Is 2 Inches Femur + 2 Inches Tibia Worth It? 1:07:28 – Fitbone vs. PRECICE vs. Mechanical “Click” Nails 1:11:13 – Syndesmotic Screws During Tibia Lengthening 1:13:15 – Swapping PRECICE 2.2 for Trauma Nails to Walk Sooner 1:15:58 – Tight Hip Flexors, Duck Ass, and Nerve Irritation After 8 cm 1:17:32 – Nail Removal and Proximal Femur Fracture Risk 1:19:30 – Conservative Lengthening for Better Athletic Recovery 1:20:07 – Where Osteomyelitis Bacteria Usually Comes From 1:21:29 – Are Bodybuilders Better Limb-Lengthening Candidates? 1:25:02 – The Pikachu Question 1:26:01 – Final Advice from Dr. Assayag and Dr. Birkholtz 1:29:38 – Outro

Thank you for watching!~CHECK OUT ALL THE LINKS BELOW FOR THE SYNDICATE & RIOT Co.!https://link.me/breederssyndicate~SUPPORT the channel or JOIN the Discord community: https://www.buymeacoffee.com/matthewriot (This channel is not monetized - any contributions are warmly appreciated & keep us going)~QUALITY GEAR (shirts, stickers, beanies, mugs etc): https://breeders-syndicate-shop.fourthwall.com~PLANT HEALTH & SEX TESTING: https://www.farmerfreeman.com  (Coupon Code: SYNDICATE5 )~Links For Dr. Rick's CHS Survey (PLEASE DO THIS IF YOU ARE EXPERIENCING NAUSEA AND SMOKING!)https://www.belly-md.com/riot

* HPTU: This week Fred Williams and Doug McBurney welcome back pastor Kevin Lea (Ret.) the "dean" of Hydroplate Theory University. * Trinary: Hear all about why only the Hydroplate Theory explains how asteroids are likely to have moons, how some are contact binaries, and now... contact trinaries! Read what the unbelievers say about them, hear what Hydroplate Theory says, and you be the judge! * Do Teachers Ever Learn? Hear all about Kevin's amazing opportunity to present creation and hydroplate to another MIT degreed PhD (not Walt Brown), Cristina Thomas, PhD at the Department of Astronomy & Planetary Science at Northern Arizona University. * The HPTU Backstory: How did HPTU come to be? Listen in on the details of a rather rough road from Calvary Chapel, to the publication of the 9th Edition, and the launch of Hydroplate Theory University. * The Windows of Heaven: Get a basic review and some of the more advanced, even mind blowing predictions and explanations from the 9th Edition of Walt Brown's "In the Beginning." * In The Beginning: Order your 9th edition of Walt Brown's amazing, enlightening, biblically sound book explaining why Earth (and the solar system) look the way they do! * Jesus Light & Design: Get the first in our series of Real Science Radio Teaching Books, all about how light and design point to Jesus Christ as the Creator and Savior of the world. * Sun Puzzles: Check out another one of Ellen McHenry's intriguing and enlightening books: Sun Puzzles - on all the curious facts about the Sun that point to an electric, (and not a nuclear) sun. * Not So: Pick up a copy or two of RSR's 2nd in our series of Real Science Radio Teaching Books: "The List of Not So Old Things.," with all the "not so old things" Bob Enyart compiled over the years!

Vanessa breaks down the biggest scientific takeaways and most actionable gems from her recent conversation with body-composition expert and author Lyle McDonald. Why does fat come off easily from some areas while other areas seem determined to hold on? And can we influence stubborn fat loss without simply getting leaner everywhere else? Create your own custom protein blend at truenutrition.com/vanessa and use code VANESSA for 20% off your first order. Let Vanessa know what your custom blend is! Now shipping internationally. Vanessa explores the physiology of stubborn body fat, including fat mobilization, blood flow, oxidation and alpha-2 receptors, and why women in particular may notice their upper body becoming lean long before their hips and thighs. She also breaks down Lyle's newest approach, Intermittent Modified Fasting, and how alternating protein-focused, low-calorie days with maintenance days may offer a more flexible way to create a calorie deficit while prioritizing muscle retention. Vanessa explains why protein becomes especially important during aggressive calorie restriction, why a maintenance day is different from a "cheat" or "feast" day, and how meal timing, appetite and ketosis can influence how sustainable a fat-loss phase feels. She also examines Lyle's proposed strategies for addressing stubborn fat—including lower-carbohydrate eating and combining higher-intensity intervals with lower-intensity activity—while separating established physiology from strategies that still require more research. YOHIMBINE SAFETY NOTE: Yohimbine is discussed in this episode for educational purposes only and is not being recommended for use. Yohimbine can cause significant side effects, including anxiety, increased heart rate and blood pressure, and may interact with medications. It should not be used during pregnancy or breastfeeding. Anyone considering yohimbine should first consult with a qualified healthcare professional. Finally, Vanessa explores the scientific mechanisms behind yohimbine and alpha-2 receptors for educational purposes, red-light therapy and blood flow, whether slower weight loss could help preserve facial fullness, and why having a maintenance strategy may be just as important as having a fat-loss strategy. In this episode: Why some areas of body fat are more resistant to fat loss Why women may lose upper-body fat before hip and thigh fat Alpha-2 vs. beta receptors and stubborn-fat physiology Fat mobilization vs. fat oxidation vs. actual body-fat loss Why blood flow matters in stubborn fat stores Protein-Sparing Modified Fasting (PSMF) explained Lyle's Intermittent Modified Fasting approach Why protein matters on very-low-calorie days Maintenance days vs. cheat or feast days How to structure lower-calorie and maintenance days around training and life Why meal timing should help manage your appetite Time-restricted eating vs. intermittent modified fasting Protein, ketosis, satiety and food preoccupation Lower-carbohydrate eating and stubborn-fat mobilization Higher-intensity intervals followed by lower-intensity activity Why walking may fit into Lyle's stubborn-fat protocol Why more cardio is not necessarily better during aggressive dieting Red-light therapy, blood flow and what the evidence does—and does not—show Yohimbine, alpha-2 receptors and important safety considerations Why mobilizing more fat does not guarantee greater fat loss Resistance training and preserving lean mass during fat loss How to create a long-term weight-maintenance range Why small course corrections may help prevent larger weight regain Can slower weight loss help preserve facial fullness? Genetics, aging and individual patterns of fat loss Why your leanest possible weight may not be where you look or feel your best Vanessa's practical takeaways for sustainable fat loss and body recomposition BACK TO SCHOOL SALE! For a limited time, save 40% sitewide at ketogenicgirl.com with code BACKTOSCHOOL40, including the Protein-Sparing Modified Fasting Library, ToneLUX Red Light Therapy Collection, and Tone Breath Ketone Analyzer. Australia, New Zealand & Southeast Asia: Save 75% on available ToneLUX and Tone products during the warehouse moving sale with code WAREHOUSE75, while supplies last. Follow @ketogenicgirl and @optimalproteinpodcast on Instagram to see visuals and posts mentioned on the podcast. Link to join the Facebook group for the podcast. The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet, supplements or exercise regimen.

What Is Dependent Personality Disorder (DPD)? Do you struggle to make decisions without someone else's approval? Do you constantly seek reassurance, fear being alone, or stay in unhealthy relationships because the thought of leaving feels terrifying? In this episode of the Ask Kati Anything Podcast, licensed therapist Kati Morton takes a deep dive into Dependent Personality Disorder (DPD). We explore the official DSM-5 diagnostic criteria, how DPD differs from anxious attachment, codependency, and borderline personality disorder (BPD), why DPD develops, and practical steps to rebuild self-trust and confidence. EPISODE SPONSOR Specialized virtual trauma treatment is available through Rebound. Founded by survivors and psychologists, Rebound provides clinically effective trauma therapy covered by leading insurance plans: https://hellorebound.com/askkatianything Timestamps 00:00 - Introduction: Understanding Dependent Personality Disorder (DPD) 01:31 - Q1: Am I Needy, Depressed, Traumatized, or Is It DPD? (DSM-5 Criteria) 10:30 - Q2: Capable at Work, But Indecisive at Home (Capability vs. Self-Trust) 15:15 - Q3: Asking Multiple People Before Making Decisions: Advice vs. Permission 18:54 - Advice vs. Reassurance: Finding What You Really Think 20:42 - Q4: Backtracking During Disagreements & Fear of Conflict 24:00 - Q5: Why Staying in Bad Relationships Feels Safer Than Being Alone 29:31 - Q6: Urgently Jumping Into Rebound Relationships 35:40 - Q7: DPD vs. Anxious Attachment, Codependency, BPD & Avoidant PD 44:33 - Q8: Where Does DPD Come From? (Genetics, Childhood, Overprotective Parenting) 53:32 - Q9: Why Does Reassurance Never Feel Like Enough? (The Reassurance Cycle) 56:31 - Q10: Transferring Dependency onto Your Therapist 01:02:03 - 5 Actionable Steps to Build Self-Trust and Overcome DPD MY BOOKS Why Do I Keep Doing This? Traumatized Are u ok? ONLINE THERAPY - Enjoy 10% off your first month If you're looking for a therapist, BetterHelp can connect you with a licensed online professional: https://betterhelp.com/kati - a portion of your signup helps support the podcast at no extra cost to you. SOCIAL X https://twitter.com/KatiMorton TikTok https://www.tiktok.com/@katimorton Substack https://substack.com/@katimorton1 Facebook https://www.facebook.com/katimorton1/ Instagram https://www.instagram.com/katimorton Pinterest https://www.pinterest.com/katimorton1/ Patreon https://www.katimorton.com/kati-morton-patreon/ PARTNERSHIPS Nick Freeman | nick@biglittlemedia.co Disclaimer: The information provided in this video is for educational and informational purposes only and is not intended as medical or mental health advice. It should not be used to diagnose or treat any health problem or disease. Always consult with a qualified healthcare professional for diagnosis and treatment. Viewing this content does not establish a therapist-client relationship. Ask Kati Anything ep. 333 | Your mental health podcast, with Kati Morton, LMFT Learn more about your ad choices. Visit megaphone.fm/adchoices

New West Genetics has been focused on crop improvement in the hemp industry since 2014. In July of 2021, the Lancaster Farming National Hemp Tour paid a visit to the New West headquarters in Fort Collins, Colorado, where Wendy Mosher sat down for an interview with the host of the Lancaster Farming podcast, Eric Hurlock. That's me. It's sort of weird to talk about myself in the third person, but anyway, on this week's show we catch up with Mosher to hear about the past five years. Back in 2021, Mosher spoke about new hybrid varieties of hemp grain that could double yields. And now five years later, that hybrid is in the middle of a market that wasn't on her radar back in 2021: renewable fuels. The oil from hemp grain makes an excellent biofuel, she said. We also talk about her work with the Hemp Feed Coalition, a group dedicated to opening the livestock feed markets for hemp. Our conversation was recorded in August before the McConnell deadline was extended to December. She welcomes closing the loopholes in the regulations. "Bad actors still, to this day, impact my company. So I want them out of there. And it's their own fault if there's a huge backlash. It's their fault for not taking care of that in their industry," she said. It's a fun conversation, so listen up and climb on board the RV Time Machine. Learn More New West Genetics newwestgenetics.com/ Hemp Feed Coalitionhempfeedcoalition.org/ ONE PLANT Lancaster Screening, Oct 24 oneplant.film/lancaster Get Tickets — ONE PLANT in Lancaster eventbrite.com Sponsors Jungmaven — hemp clothing, made in the USA jungmaven.com IND Hemp — Fort Benton, Montana indhemp.com Forever Green, distributors of the KP4 Hemp Cutter hempcutter.com

Everybody says they want results.But what happens when the beliefs you have about fitness are the exact things keeping you from making progress?Tonight we're reacting to more viral fitness takes — from people claiming everybody asks them how to get shredded, to losing 40 pounds because of a waist trainer, to the idea that your weight is completely outside of your control.This isn't about expecting everybody to have the perfect body. It's about attacking the mindset that keeps people stuck.Training matters. Nutrition matters. Consistency matters. Genetics and medical factors can affect the process, but that doesn't mean your daily behaviors are meaningless.Sometimes making progress starts with being willing to question the story you've been telling yourself.We're going through these clips and MORE tonight.Which fitness belief do you think holds people back the most?

Would we ever colonize space with prisoners? From penal colonies to prison planets, we explore whether exile could become a second chance, a new civilization, or a nightmare with rockets.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurCheckout Mad Kings : https://nebula.tv/madkings?ref=isaacarthur

Would we ever colonize space with prisoners? From penal colonies to prison planets, we explore whether exile could become a second chance, a new civilization, or a nightmare with rockets.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurCheckout Mad Kings : https://nebula.tv/madkings?ref=isaacarthur

Send us Fan MailWhat if the stigma surrounding fat bodies is itself a health issue?Chrystal sits down with writer, speaker, patient advocate, and weight-stigma educator Ragen Chastain for a deep conversation about anti-fat bias, healthcare, BMI, medical research, GLP-1 medications, weight-loss culture, racism, and the ways the weight-loss industry shapes the conversation around fat bodies.We talk about why shame doesn't work, why “everybody knows” isn't evidence, who gets represented in medical research, how BMI became so influential, and what happens when healthcare systems are built around assumptions about fat bodies.Ragen also talks about her work with Louise Adams on Exposing Obesity Incorporated, a podcast examining the weight-loss industry's influence and messaging.Most importantly, we talk about what happens when we stop treating fat bodies as problems that need to be fixed.Your body is not wrong.CHAPTERS00:00 Welcome + Ragen Chastain02:31 Is Anti-Fat Bias Making People Sick?03:27 Why Shame Doesn't Work04:52 The Weight-Loss Industry's Playbook07:22 Exposing Obesity Incorporated09:04 “Oh Please”10:14 Industry Influence11:24 Weight Stigma & Healthcare Inequality13:20 Repetition & “Common Knowledge”14:04 Anti-Stigma as Marketing15:14 Fat Patients & Medical Bias17:14 Educating Healthcare Providers19:06 GLP-1s20:37 Cortisol & Stress22:15 Racism & Anti-Blackness23:09 Medical Research & Fat Bodies24:46 The “150-Pound White Guy” Problem27:25 “Everybody Knows”28:36 Is Fatness a Disease?30:31 Genetics & Weight Regain31:41 The History of BMI34:00 The Origins of Weight-Loss Culture35:08 The Lifelong Disease Narrative36:07 Moving the Goalposts38:35 Informed Consent39:15 Race, BMI & Anti-Fatness40:30 Fighting Your Body vs. Fighting Stigma42:20 Weight-Stigma Research & Industry Funding43:29 Find Ragen45:16 Catching Up47:00 GoodbyeSupport the showBigSexyChat.com appreciates you and our community. We do this for you, so if you ever have any ideas about a subject we can discuss for you, email us at bigsexychatpod@gmail.com.You can find us on Facebook and Instagram as BigSexyChat.Twitter (who knows how long we will stay there) is BigSexyChatPodCheck out our merch at  www.BigSexyTees.com  (credit to Toni Tails for setting this up for us!)Chrystal also sells sex toys via her website BlissConnection.com and you can use the code BSC20 for 20% off. Big thanks to our Sponsor Liberator Bedroom Adventures. We ADORE the products from Liberator.  And, to be clear, we all loved their products even before they became a sponsor!

In this episode we speak with Rob Klose, Professor of Genetics at the University of Oxford, about how CpG islands help control gene expression and chromatin regulation during development. We discuss how his lab connected CpG islands to histone modifications and chromatin regulation. He describes how KDM2A and KDM2B were found to recognize CpG islands, how this led to the study of H3K36 methylation at promoters, and how BioCAP was developed to isolate non-methylated DNA. He also explains how this work showed that CpG islands are conserved across vertebrates. We also talk about the unexpected link between CpG islands, PRC1, and PRC2. He outlines how PRC1-dependent H2A ubiquitylation can recruit PRC2 and promote H3K27 trimethylation, and how his lab tested these pathways with ectopic tethering experiments. He further discusses what is known about H2A ubiquitylation, how it may affect access of the pre-initiation complex, and why the exact mechanism is still not fully understood. Another major theme is how CpG islands may help maintain gene expression states. We cover how SET1 at CpG islands helps prevent premature transcription termination at a subset of genes, especially those that are lowly transcribed, and how Polycomb can help lock genes in an off state. He also explains how the plus-one nucleosome and other early elongation barriers fit into this framework. Finally, we discuss the value of combining bulk genomics with live-cell imaging. He describes how single-cell approaches reveal stochastic, burst-like transcription that is hidden by ensemble measurements, and why his lab is now building synthetic systems and mathematical models to test how CpG islands, enhancers, and core promoters work together to shape transcription. References Blackledge NP, Zhou JC, Tolstorukov MY, Farcas AM, Park PJ, Klose RJ. CpG islands recruit a histone H3 lysine 36 demethylase. Mol Cell. 2010 Apr 23;38(2):179-90. doi: 10.1016/j.molcel.2010.04.009. PMID: 20417597; PMCID: PMC3098377. Blackledge NP, Farcas AM, Kondo T, King HW, McGouran JF, Hanssen LLP, Ito S, Cooper S, Kondo K, Koseki Y, Ishikura T, Long HK, Sheahan TW, Brockdorff N, Kessler BM, Koseki H, Klose RJ. Variant PRC1 complex-dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation. Cell. 2014 Jun 5;157(6):1445-1459. doi: 10.1016/j.cell.2014.05.004. Epub 2014 May 22. PMID: 24856970; PMCID: PMC4048464. Long HK, King HW, Patient RK, Odom DT, Klose RJ. Protection of CpG islands from DNA methylation is DNA-encoded and evolutionarily conserved. Nucleic Acids Res. 2016 Aug 19;44(14):6693-706. doi: 10.1093/nar/gkw258. Epub 2016 Apr 15. PMID: 27084945; PMCID: PMC5001583. Huseyin, M.K., Klose, R.J. Live-cell single particle tracking of PRC1 reveals a highly dynamic system with low target site occupancy. Nat Commun 12, 887 (2021). https://doi.org/10.1038/s41467-021-21130-6 Related Episodes Polycomb and Three-Dimensional Genome Organisation (Oliver Bell) Polycomb Proteins, Gene Regulation, and Genome Organization in Drosophila (Giacomo Cavalli) CpG Islands, DNA Methylation, and Disease (Sir Adrian Bird) Contact Epigenetics Podcast on Mastodon Epigenetics Podcast on Bluesky Dr. Stefan Dillinger on LinkedIn Active Motif on LinkedIn Active Motif on Bluesky Email: podcast@activemotif.com

Six years of experts. One question asked every single time, and a pile of predictions that either aged beautifully or fell apart on contact with reality. Some of the boldest claims came wrapped in credentials, while some of the quietest answers turned out to be the ones worth keeping. Year six was when the wellness conversation got loud enough that discernment became the real skill.On this episode of The Next Frontier Files, Jenn Trepeck plays back year six of the next frontier in wellness answers and hands-down verdicts. Fat cells that remember your old weight. Menopause research that still has not arrived. Peptide therapy sitting next to skin tanning in the same sentence. Artificial intelligence in medicine, and the guest who predicted the backlash a year before it happened. Plus a hydrogen claim about living into the thousands that deserves the raised eyebrow it gets.What You Will Learn in This Episode:✅ Why fat cell memory rewrites the RNA of your cells and makes weight maintenance harder after rapid loss, especially after GLP-1 drugs✅ How genetics and the microbiome shift with your environment, which is why one-size-fits-all advice keeps failing✅ What methylation risk scores and biological age testing could unlock as they move toward FDA approval✅ The difference between a wearable data point and the time, care, and listening that actually changes outcomesThe Salad With a Side of Fries podcast, hosted by Jenn Trepeck, explores real-life wellness and weight-loss topics, debunking myths, misinformation, and flawed science surrounding nutrition and the food industry. Let's dive into real-life wellness and weight loss, including drinking, eating out, and skipping the grocery store.TIMESTAMPS:00:00 Jenn shares why seven years of wellness trends became a seven-part miniseries built from one rapid-fire question04:45 The year six theme arrives, exploring fat cell memory and being on the same team as your own body05:19 Professor Ferdinand von Meyenn on prevention, health span, and incentivizing care before disease07:38 Dr. Kathy Campbell on genetics and the microbiome as two universes of variables and complexity08:57 Hannah Went discusses the methylation risk scores and FDA approval09:33 Vince Sant on peptide therapy for joint health, muscle recovery, and where the claim drifts10:41 Zora Benhamou and Monica Packer discuss menopause research gap and gender neutral studies11:56 Ashley Fillmore feels like the future is bright, but hopes it will be more affordable for the average consumer13:01 Jenn Malecha shares a new frontier of functional medicine for pets16:23 Dr. Dana Stern on artificial intelligence and predictive health18:25 Dr. Andrea Nakayama feels the frontier is going to be wearables, but has thoughts about where she wishes it was going19:39 Greg the Hydrogen Man claims reversed aging and a device that does not exist yet21:58 Martin Pytela hopes that the HHS will find that drugs should be regulated separately from food23:44 Getting back to basics with real food, daily movement, consistency, and self-kindnessKEY TAKEAWAYS:

On this episode we're joined by Dr. Bronson Strickland and Dr. Mick Hellickson to explain the results of their lengthy study on culling bucks. Genetics and nutrition are buzz words that deer biologists reference all the time. We can help provide enhanced nutrition in a variety of ways but what about genetics? Can you cull your way to better bucks over time? We get this question answered as they explain the 20 plus year research project that set out to understand this issue. Its amazing what they learned. Listen, Learn and Enjoy.  If you enjoyed this Gamekeeper episode, send the guys a message and don't forget to include your contact info so we can reach you if you win a prize! Support the showStay connected with GameKeepers: Instagram: @mossyoakgamekeepers Facebook: @GameKeepers Twitter: @MOGameKeepersYouTube: @MossyOakGameKeepers Website: https://mossyoakgamekeeper.com/Enter The Gamekeeper Giveaway: https://bit.ly/GK_GiveawaySubscribe to Gamekeepers Magazine: https://bit.ly/GK_Magazine Buy a Single Issue of Gamekeepers Magazine: https://bit.ly/GK_Single_Issue  Join our Newsletters: Field Notes - https://bit.ly/GKField_Notes | The Branch - https://bit.ly/the_branchHave a question for us or a podcast idea? Email us at gamekeepers@mossyoak.com 

Autoimmune disease is showing up in people with no family history, at ages nobody expected, and most people say that it's bad luck or bad genes. Dr. Aly Cohen stopped accepting that answer twenty years ago, and it started with her dog. He was a four and a half year old golden retriever who got sick out of nowhere with autoimmune liver disease, which is rare for dogs. She started looking at his water, his food, the plastic toy that lived in his mouth. Then she looked at her own kids, and then at her patients, and the question stopped being about the dog. If a healthy young animal can develop autoimmune disease out of nowhere, what is doing the same thing to us?. She has been chasing this question ever since. She explains the epigenome, which is the layer of proteins sitting on your genes deciding which ones get switched on. Having the gene is not the same as expressing it, and a lot of what flips that switch is what's coming into your body every day. We get into what a real autoimmune intake should ask, from your water filter to your job to what happened in your childhood. She also points out that vitamin D matters enormously in autoimmune disease, it's all over the literature and even on the board exams, and she almost never sees a patient show up with it tested. You have far more say in what happens to your health, and this is where you find out how much. Get Dr. E's FREE 5 Red Flag Phrases guide here: https://freechapter.lpages.co/5-phrases-that-are-red-flags/ Want more practical health tips? Join my newsletter! https://freechapter.lpages.co/newsletter-opt-in/ Check us out on social media: https://www.instagram.com/drefratlamandre https://www.facebook.com/drefratlamandre https://www.tiktok.com/@drefratlamandre #functionalmedicine #drefratlamandre #medicaldisruptor #NPwithaPHD #nursepractitioner #medicalgaslighting Chapters 0:00 - Introduction 7:08 - How a Dog's Illness Changed Her Practice 10:13 - The Environmental Questions Rheumatologists Skip 22:06 - Genetics vs. Environment in Autoimmunity 30:02 - Inside "Detoxify" and the 80/20 Approach 36:07 - Rapid Fire: Plastics, Flares, and Wellness Traps Guest Links: FB: https://www.facebook.com/thesmarthuman IG: https://www.instagram.com/thesmarthuman/ Website:https://alycohenmd.com | https://thesmarthuman.com Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode, we sit down with geneticist Ryan Rosner, PhD, to explore what our DNA can tell us about performance, health, longevity, and the future of human enhancement.We get into the genetics of elite athletes like Devin Larratt, what genetic sequencing can actually reveal, “superhuman” mutations, gene therapy, cognition, mitochondrial function, bone density, Alzheimer's risk, peptides, supplementation, and whether we're approaching a point where humans can intentionally alter their own biology.Ryan also explains why he believes genetic sequencing is one of the most underutilized tools available today, where the science is still limited, and why the next generation of gene therapies could look very different from anything we've seen before.

On September 17, 2026, the GBI announced murder and related charges against Rashad Jackson in the 2020 death of Tyler Hall in Norcross, Georgia. Hall, 21, was found shot in his home in August 2020. The breakthrough came from advanced DNA and genealogy work by the GBI Cold Case Unit and Othram. Jackson is charged, not convicted, and the investigation remains active.

How big could human civilization become? From trillion-person worlds to Dyson swarms, galaxy-spanning cultures, and digital minds, we explore just how far humanity could scale.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurCheckout Gods & Monsters: https://nebula.tv/curiousarchive/gods-and-monsters?ref=isaacarthur

How big could human civilization become? From trillion-person worlds to Dyson swarms, galaxy-spanning cultures, and digital minds, we explore just how far humanity could scale.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurCheckout Gods & Monsters: https://nebula.tv/curiousarchive/gods-and-monsters?ref=isaacarthur

Thank you for listening!Links For Dr. Rick's CHS Survey (PLEASE DO THIS IF YOU ARE EXPERIENCING NAUSEA AND SMOKING!)https://www.belly-md.com/riotDr. Rick's Vitamin Packs - 15% Off with Coupon Code: RIOThttps://www.belly-md.com~CHECK OUT ALL THE LINKS BELOW FOR THE SYNDICATE & RIOT Co.!https://link.me/breederssyndicate~SUPPORT the channel or JOIN the Discord community: https://www.buymeacoffee.com/matthewriot (This channel is not monetized - any contributions are warmly appreciated & keep us going)~QUALITY GEAR (shirts, stickers, beanies, mugs etc): https://breeders-syndicate-shop.fourthwall.com~PLANT HEALTH & SEX TESTING: https://www.farmerfreeman.com  (Coupon Code: SYNDICATE5 )

In this episode, I interview Dr. Garrett Cooper, a recent PhD graduate from Emory's Genetics and Molecular Biology program. He now works as a research scientist for Exact Sciences.Our conversation is perfect for anyone interested in pursuing an industry job in the biotech sector. We open with a conversation about how Garrett entered the field of genetics and what ultimately led him to pursue a career in the biotech sector. Additionally, a large portion of our conversation is dedicated to the advice he offers to others pursuing a job in the biotech industry. He provides insight into how to interview successfully, how to navigate the hiring process, and the unique experiences that made him a competitive candidate.Dr. Cooper also hosts a YouTube channel called Genomify with Garrett, where he teaches bioinformatics. The link is below to check it out!Genomify with Garrett: https://garrettc00per.github.io/tutorials/

* 9/11 Questions: This week Fred Williams and Doug McBurney recall the events of 9/11/2001 in light of questions regarding structural issues, the collapse of the towers and building 7, and whether or not there is convincing evidence that 9/11 was an inside job. * Building 7: We discuss what has emerged as the most compelling question surrounding the events at Ground Zero that day: Why did Building 7 collapse the way it did?   * Credible Evidence: While many dismiss the reports of the 9/11 Commission, FEMA, and the NIST, we hold the evidence that people on both sides argue about, (including credible reports from contrarian Engineers) up against Rob Stadler, PhD's six criteria for high confidence science.   * Jesus Light & Design: Get the first in our series of Real Science Radio Teaching Books, all about how light and design point to Jesus Christ as the Creator and Savior of the world.   * In The Beginning: Order your 9th edition of Walt Brown's amazing, enlightening, biblically sound book explaining why Earth (and the solar system) look the way they do!   * Sun Puzzles: Check out another one of Ellen McHenry's intriguing and enlightening books: Sun Puzzles - on all the curious facts about the Sun that point to an electric, (and not a nuclear) sun.   * Not So: Pick up a copy or two of RSR's 2nd in our series of Real Science Radio Teaching Books: "The List of Not So Old Things.," with all the "not so old things" Bob Enyart compiled over the years!

Aaron Zeeman, better known as Professor Potgrower, is a Hawaiʻi Island cultivator, breeder, author, and cannabis culture writer who has spent more than 30 years in Hawaiʻi. He is the founder of Big Island Genetics, author of The Hemp Ritual Handbook: A Slightly Disrespectful Guide to Cannabis Culture, and a contributor to SKUNK Magazine. His work focuses on Hawaiʻi's legacy genetics, the people and culture that preserved them, and what has been gained — and lost — as cannabis moved from prohibition into the modern legal era.

I ran 70,000km across the world's toughest deserts to lose weight, and I got heavier, more inflamed and sicker every year. I assumed the problem was discipline. It took one genetic test to show me it never was. In this solo episode I make the case that your DNA is the single most valuable test you will ever do. Not because it tells you the most, but because it is the only test whose result is still true in fifty years. Your bloods reflect the last few weeks. Your microbiome shifts with every trip and every course of antibiotics. Your hormones move across the month and the decade. Your DNA does not move at all. I go through all eight areas a comprehensive genetic panel covers, what you actually learn from each one, and why a variant is a tendency rather than a verdict. IN THIS EPISODE My own results, and the cascade that explains twenty-five years of getting it wrong Why genetics is different from every other test you will ever do Genetics loads the gun, environment pulls the trigger: what that actually means in practice The single-gene trap, and why the MTHFR obsession has it upside down Digestion, energy, hormones, stress and cognition, inflammation, athletic performance, DNA repair and detoxification, one at a time The difference between nutritional dosing and nutrigenomic dosing, and why more vitamin D was not working for me Why genetics alone is not enough, and what has to sit alongside it Why it is almost never discipline THE DNA BLUEPRINT PACKAGE Practitioner-only genetic testing, ninety-two genes and a hundred and thirteen variants across a report of roughly a hundred and twenty-one pages, read by me alongside a full Cell Blueprint assessment and turned into a complete personal health programme in a ninety-minute one-on-one. Available throughout New Zealand. Australia coming soon. https://www.lisatamati.com/dna/ GO DEEPER Dr Sam Shay on methylation, inflammation and exercise-induced obesity: https://www.lisatamati.com/podcast--dr-sam-shay_1/ Dr Mansoor Mohammed on how your variants change what you eat and how you train: https://www.lisatamati.com/podcast-mansoor-mohammed/ Read the long-form article: https://www.lisatamati.com/blog/ ALSO FROM LISA Re:juvenate Pro, the foundational immune ageing formula from Aevum Labs: https://shop.lisatamati.com/pages/rejuvenate Re:NRG, our next-generation NAD support, is coming. Join the waitlist for first access: https://shop.lisatamati.com/pages/nad-next-gen-waitlist Weekly longevity insights, free: https://www.lisatamati.com/lisa Questions or feedback: lisa@lisatamati.com Pushing the Limits is hosted by Lisa Tamati, genetics practitioner, co-founder and Chief Science Officer of Aevum Labs, and former professional ultra-endurance athlete. Author of three books and one audiobook.

This week on High on Home Grown, we're back with another Listener Mail episode, answering questions from the community covering everything from making your grow more comfortable on your back to dealing with heavy rain outdoors, genetic variation between plants and the growing advice we've completely changed our minds about over the years. SKD, the grower with the SCROG and the dodgy back, is back looking for more ways to make growing more ergonomic. We discuss ways of making the grow room easier on your body, whether raising plants can help, and whether automatic watering systems are actually worth the investment or just another gadget taking up space in the grow room. Free Nugz has a much more immediate problem, with tall outdoor plants being hit by unexpected heavy rain and already showing the first signs of bud rot. We discuss what growers can realistically do when the weather turns against them, how to reduce the chances of losing an outdoor harvest, and what to look out for when you're trying to get big plants through the final stretch of the season. Toploader has perhaps the most important question of the episode: Does anyone have Milky Amber's phone number? We're still waiting for the appropriate authorities to respond. ChronicG asks why two plants from the exact same packet of seeds can sometimes finish looking, smelling and even behaving completely differently. We get into genetics vs environment, phenotype variation and how much influence the growing conditions can actually have on the final expression of a cannabis plant. Finally, BudsAndBeans asks the panel to look back at their own growing journeys and reveal one thing they used to believe about growing cannabis that experience completely changed their mind about. Sometimes the best lessons aren't the things you learn from a book, but the things you learn after doing something wrong for five years! Another episode of community questions, grow-room experience, practical advice, genetics, outdoor growing and the occasional question that absolutely should not have made it onto the podcast.

What happens when the machines still work, but nobody remembers how they were built? We explore technological amnesia, black-box automation, lost expertise, and civilizations trapped inside inherited technology.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurCheckout Alien Data Arks, Outsider Aliens, and our Alien Life Collection: https://nebula.tv/isaacarthur/alien-life-collection

What happens when the machines still work, but nobody remembers how they were built? We explore technological amnesia, black-box automation, lost expertise, and civilizations trapped inside inherited technology.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurCheckout Alien Data Arks, Outsider Aliens, and our Alien Life Collection: https://nebula.tv/isaacarthur/alien-life-collection

Jennifer Veatch shares her story of making it through through two years of genetic testing and IVF before arriving where she is today, in her third trimester getting ready to meet her baby. Connect with the guest: Penny 'N Pals on Amazon LinkedIn Grow with us on ⁠IP+⁠! Informed Pregnancy Media presents two all new intimate short-form video series following Garrett and HeHe's real-time pregnancy journeys as they prepare for an empowered birth and postpartum experience. Each episode features weekly updates with personal photos and videos to help bring these raw stories to life, a visually dynamic guide through each mother's emotional and physical experiences. ⁠Watch Growing with Garrett⁠ ⁠Watch Growing with HeHe⁠ Keep up with Dr. Berlin and Informed Pregnancy Media online! ⁠⁠⁠informedpregnancy.com⁠⁠⁠ ⁠⁠⁠@doctorberlin⁠⁠⁠ ⁠⁠⁠Youtube⁠⁠⁠ ⁠⁠⁠LinkedIn⁠⁠⁠ ⁠⁠⁠Facebook⁠⁠⁠ ⁠⁠⁠X⁠⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode, Dr. Jeffrey Gladden and psychiatrist Dr. Matt Bernstein discuss the evolving landscape of mental health treatment. Bernstein shares his extensive experience in psychiatry, particularly with serious mental health conditions, and highlights the limitations of traditional medication approaches. He advocates for a more holistic view that considers metabolic health and mitochondrial function as critical components in understanding and treating mental health issues. The conversation also delves into the benefits of the ketogenic diet, cognitive flexibility, and the complexities of medication management in psychiatric care. In this conversation, Dr. Gladden and Matt Bernstein explore the intricate relationship between mental health, metabolism, exercise, and the role of psychedelics in therapy. They discuss the negative metabolic impacts of psychotropic medications, the significant benefits of exercise for mental health, and the importance of understanding individual genetics in managing depression. The conversation also delves into the role of lactate in brain health, mitochondrial function, and the potential of psychedelic therapies for personal transformation. Ultimately, they emphasize the need for a holistic approach to health that encompasses physical, mental, and spiritual well-being. For Audience Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now   Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/!    Takeaways ·       Matt Bernstein has 26 years of experience in psychiatry. ·       He works with serious mental health conditions like bipolar disorder and schizophrenia. ·       Traditional psychiatric medications often lead to metabolic and neurological side effects. ·       Anhedonia is a significant issue in mental health, meaning a lack of pleasure. ·       There is a need for a fresh perspective on mental health rooted in metabolism. ·       Mitochondrial dysfunction is linked to serious mental illnesses. ·       The ketogenic diet can be an effective intervention for mental health. ·       Cognitive flexibility is crucial for managing mental health conditions. ·       Medication management is complex and requires careful consideration. ·       Not all patients can or should stop their medications completely. Psychotropic medications can negatively impact metabolic health. ·       Exercise has a greater effect on depression than antidepressants. ·       Intense exercise is crucial for mental health benefits. ·       Genetics play a significant role in individual responses to depression. ·       Lactate production during exercise is beneficial for brain health. ·       Mitochondrial health is essential for longevity and mental well-being. ·       Stress affects both neurological and hormonal health. ·       Psychedelic therapies can provide transformative experiences for some individuals. ·       Social connectedness and purpose are vital for longevity. ·       Holistic approaches to health should integrate physical, mental, and spiritual aspects.   Chapters 00:00 Introduction to Mental Health Perspectives 02:58 The Limitations of Traditional Psychiatry 05:54 Exploring Root Causes in Mental Health 09:05 The Role of Metabolism and Mitochondrial Function 11:54 The Ketogenic Diet as a Therapeutic Approach 14:59 Cognitive Flexibility and Mental Health 17:56 Medication Management in Psychiatric Care 23:24 Impact of Psychotropics on Metabolism 24:49 The Role of Exercise in Mental Health 27:53 Genetics and Personal Insights on Depression 29:32 Lactate Production and Brain Health 32:46 Mitochondrial Health and Longevity 36:30 Mind-Body Connection and Stress Management 39:08 Psychedelic-Assisted Therapies 45:07 Optimizing Longevity and Health Span To learn more about Dr. Matt Bernstein:Website: www.accordmh.com LinkedIn: www.linkedin.com/in/mattbernsteinmd   Reach out to us at:    Website: https://gladdenlongevity.com/     Facebook: https://www.facebook.com/Gladdenlongevity/    Instagram: https://www.instagram.com/gladdenlongevity/?hl=en     LinkedIn: https://www.linkedin.com/company/gladdenlongevity    YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw    

Watch every episode ad-free & uncensored on Patreon: https://patreon.com/dannyjones Valentine is a world-class spear-fisher, freediving instructor & author. https://www.instagram.com/valentinethomas SPONSORS https://capl.onelink.me/vFut/zralgyl0 - Download Cash App today. https://GLD.com - Use code DANNYJONES for 40% off. https://whiterabbitenergy.com/?ref=DJP - Use code DJP for 20% off. EPISODE LINKS https://www.instagram.com/valentinethomas *NEW* DJP MERCH https://dannyjonespodcast.com Get paid to make clips from the show: https://discord.com/invite/dannyjones FOLLOW DANNY JONES https://www.instagram.com/dannyjones https://twitter.com/jonesdanny OUTLINE 00:00 - Freediving while pregnant 03:29 - Abandoned NASA base on Acension Island 09:19 - Bull shark encounters while fishing 15:15 - Valentine's tiger shark encounter 18:16 - Why shark populations are exploding 23:35 - The tasteless fish that is useless 30:51 - Tracking seafood with blockchain 32:57 - The truth about farmed salmon 43:11 - Most of Earth's biomass is farmed animals 51:39 - The sweaty t-shirt study 55:06 - How birth control changes your partner selection 59:13 - Overfishing in Europe vs. America 01:08:27 - Facial recognition monitoring bluefin tuna fishing 01:11:03 - Florida's controversial fishing quota system 01:19:47 - Spearfishing around Gulf oil rigs 01:21:36 - Freediving vs. scuba 01:26:05 - Manny Puig's handmade hunting trident 01:33:36 - The fatal Cocos Island shark attack 01:38:33 - Shark influencers are lying to you 01:48:14 - The shark attack in Egypt 01:56:02 - Valentine's theory about environmental activism 02:03:55 - Austrailia's new social media law 02:05:42 - Fishing channels are getting in trouble 02:09:08 - Australia's proposed algorithm opt-out 02:11:25 - Phones & dangers of EMF exposure 02:16:48 - Genetics' role in longevity 02:21:14 - Lindsay Clancy & post-partum depression 02:28:15 - How Valentine learned Spanish 02:33:16 - What recreational fishermen can help sustainability Learn more about your ad choices. Visit podcastchoices.com/adchoices

You've probably been warned that if you don't finish that course of antibiotics, you could wind up battling antibiotic-resistant bacteria. But a growing body of research suggests that the opposite might be true. What does this mean for you and your next sinus infection? Flora talks with antimicrobial resistance expert Amy Mathers to find out.Plus, the driver of fibromyalgia, a condition that can cause debilitating chronic pain and brain fog, has been something of a mystery. Patients' imaging and blood work often turn up normal, and many have felt dismissed by doctors.A recent large-scale study identified a group of genes associated with the disease, a breakthrough that may help doctors understand people's risk of developing the condition and reveal something about the nature of this mysterious illness. Flora talks with Nasa Sinnott-Armstrong, one of the study's lead authors.Guests:Dr. Amy Mathers is medical director of antimicrobial stewardship and an associate professor of medicine and pathology at the University of Virginia School of Medicine.Dr. Nasa Sinnott-Armstrong is an assistant professor of computational biology and public health at Fred Hutch Cancer Center in Washington state.Transcript will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Dr. Jared Rutter, PhD, Professor of Biochemistry at the University of Utah and Howard Hughes Medical Institute Investigator, is a leading expert on mitochondria and metabolism. He explains how mitochondria produce the energy for your cells to work but also how they regulate cell growth and replication and thereby contribute to health and disease. We also discuss how mitochondria are linked to aging, cancer, and other diseases. Our conversation explores your metabolism as the composite of trillions of individual cells and points to new ways to improve health, avoid, and treat diseases. Show notes: https://go.hubermanlab.com/297-jared-rutter Pre-order Protocols: https://protocolsbook.com Thank you to our sponsors AG1: https://drinkag1.com/huberman Joovv: https://joovv.com/huberman BetterHelp: https://betterhelp.com/huberman Eight Sleep: https://eightsleep.com/huberman Function: https://functionhealth.com/huberman Timestamps (00:00:00) Jared Rutter (00:02:29) Metabolism, Cells; Aging (00:08:36) Mitochondria, Origin & Cell Complexity (00:13:07) Sponsors: Joovv & BetterHelp (00:15:16) Mitochondria Genome, Inheritance (00:18:18) Mitochondria & Spatial Distribution; Cell-Specific Metabolism (00:25:59) Nutrient Energy, Hormones, Fat Cells (00:31:13) Glucose, ATP Conversion, Pyruvate (00:36:41) Cell Choice: Energy or Growth, Cancer; Virus (00:46:02) Sponsors: AG1 & Eight Sleep (00:48:36) Microbiome, Role of Humans (00:51:44) Molecule Discovery Process, MPC1, MPC2 (00:59:42) Cell Resource Sensing, Fasting, Glucagon, Fat Cells; Neurons, Heart (01:07:03) Cell Resource Allocation, MPC, Heart Failure; Disease (01:11:46) Sponsor: Function (01:13:24) Cell Size vs Fuel Balance, Cell Identity & Disease (01:20:43) MPC Discovery, Genetics, Model Systems (01:24:29) Lactate, Oxygen, Exercise; Energy Prioritization Hierarchy (01:31:32) Cancer, Mutations, Metabolism Changes & Warburg Effect (01:36:18) Cancer Challenges & Therapies (01:43:00) Therapy Combinations, Unique Cancer Mutations & Metabolism (01:48:31) Technology to Visualize Metabolism; Disease, Metabolism & Scents (01:56:34) Excess Energy & Mitochondria, Reactive Oxygen Species (02:01:12) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices