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Jason Brown returns for a nuanced discussion about Zone 2 cardio, walking, conditioning, stress, recovery, and how cardio should fit into an individual's life.Jason joins me to discuss:• Whether Zone 2 cardio is actually overrated• How much of Zone 2's benefit comes from simply getting people moving• The value of reducing sedentary time and increasing daily activity• The relationship between Zone 2-style activity, NEAT, and mental health• Why getting outside and moving can provide benefits beyond fitness adaptations• Looking at cardio and all training through the lens of nervous system regulation• Accounting for the total stress already present in someone's life• Why cardio recommendations should begin with the individual's available time and capacity• The nuanced debate around whether walking counts as exercise• Why sprint training should not be treated as Zone 2 cardio• Why average heart rate during lifting or high-intensity training does not prove someone received a Zone 2 stimulus• The difference between cardiovascular strain and sustained aerobic work• Why exercise labels matter less than matching the activity to the person's needs• Jason's thoughts on the current state of online coaching• And much moreFollow Jason on Instagram:@jasonbrowntrainingCHAPTERS01:04 Setting Up the Zone 2 Controversy01:59 Who Is Zone 2 Cardio For?05:05 Social Media Hot Takes07:02 The Benefits of Sustained Aerobic Work10:41 Andrew's Questions About Zone 214:45 Mechanisms and Aerobic Adaptations21:13 Time Constraints and Effective Dosing29:07 Does Walking Count as Exercise?30:53 Walking as Therapy33:20 Regulation Matters More Than Debates34:09 Plug-and-Play Training35:40 Why Speed Training Is Not Zone 237:35 The Limits of Heart Rate as a Proxy39:39 Genetics and Individual Cardio Needs44:08 Making 30 to 60 Minutes Count47:21 Assessments and Coaching Standards50:40 The Reality of Online Coaching54:49 Aerobic Training Requires Time55:45 Final Thoughts and Where to Find JasonSUPPORT THE SHOWIf this episode helped you think differently about Zone 2 cardio, walking, recovery, or conditioning:• Subscribe and check out more episodes• Share the episode on social media and tag @andrewcoatesfitness• Send it to someone who believes cardio needs to be intense to be worthwhileFOLLOW ANDREW COATESInstagram: @andrewcoatesfitnesshttps://www.andrewcoatesfitness.comPARTNERS AND RESOURCESRP STRENGTH APPUse code COATESRP:https://www.rpstrength.com/coatesJUST BITE ME MEALSUse code ANDREWCOATESFITNESS for 10% off:https://justbitememeals.comMACROSFIRST — FREE PREMIUM TRIAL• Download MacrosFirst• Begin setting up your account• When asked, “How did you hear about us?” enter: ANDREWKNKG BAGS — 15% OFFhttps://www.knkg.com/Andrew59676VERSA GRIPPShttps://www.versagripps.com/andrewcoatesTRAINHEROIC — FREE 90-DAY TRIAL• Visit: https://www.trainheroic.com/liftfree• Reply to the email you receive or email trials@trainheroic.com• Let them know Andrew sent youL1 BIOMECHANICS AND ASSESSMENT COURSEUse code COATES:https://pro.activelifeprofessional.com/assessmentworkshopevents
Your immune system is built to hunt invaders, but every so often it turns its weaponry on your own tissues. Over the last 50 years, autoimmune disease has gone from an uncommon condition to something almost everyone knows at least one person living with, and the two variables that move symptoms more than anything are almost never discussed in a 10-minute doctor's appointment. Inside today's episode, I take the umbrella view on autoimmunity, covering how the whole category works and what the underlying mistake looks like whether it lands on the thyroid in Hashimoto's, the joints in rheumatoid arthritis, the nerve coating in MS, or half a dozen organs at once in Lupus.Topics discussed: - The Rising Autoimmune Curve- The Immune Balance Tipping Point- Why 80% of Patients Are Women- The Hormone Picture in Autoimmune Disease- Oral Contraceptives and Autoimmune Risk- Gut Microbiome and Immune History- Trauma, PTSD, and Chronically Low Cortisol- The Nutrition Ladder for Autoimmune- AIP, Wahls, and Keto for Severe Cases---------- My Live Program for Coaches: The Functional Nutrition and Metabolism Specialization www.metabolismschool.com---------- [Free] Metabolism School 101: The Video Serieshttp://www.metabolismschool.com/metabolism-101----------Subscribe to My Youtube Channel: https://youtube.com/@sammillerscience?si=s1jcR6Im4GDHbw_1----------Grab a Copy of My New Book - Metabolism Made Simple---------- Stay Connected: Instagram: @sammillerscienceYoutube: SamMillerScience Facebook: The Nutrition Coaching Collaborative CommunityTikTok: @sammillerscience----------“This Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast and the show notes or the reliance on the information provided is to be done at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment and is for educational purposes only. Always consult your physician before beginning any exercise program and users should not disregard, or delay in obtaining, medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. By accessing this Podcast, the listener acknowledges that the entire contents and design of this Podcast, are the property of Oracle Athletic Science LLC, or used by Oracle Athletic Science LLC with permission, and are protected under U.S. and international copyright and trademark laws. Except as otherwise provided herein, users of this Podcast may save and use information contained in the Podcast only for personal or other non-commercial, educational purposes. No other use, including, without limitation, reproduction, retransmission or editing, of this Podcast may be made without the prior written permission of Oracle Athletic Science LLC, which may be requested by contacting the Oracle Athletic Science LLC by email at operations@sammillerscience.com. By accessing this Podcast, the listener acknowledges that Oracle Athletic Science LLC makes no warranty, guarantee, or representation as to the accuracy or sufficiency of the information featured in this Podcast."
The Tank Talk Podcast on Instagram: https://www.instagram.com/tank_talk_podcast?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw== The Tank Talk Podcast on TikTok: https://www.tiktok.com/@tanktalkpodcast?is_from_webapp=1&sender_device=pc The Tank Talk Facebook group is a place to share your aquariums, ask questions or just hang out with cool people: https://www.facebook.com/groups/1674032529542132/ Johns website with live plants, live snails fish food, chemicals and all the equipment you need for your aquarium. Plus fun KGTropicals merch: https://keepfishkeeping.com Jasons website where you can order Primetime Aquatics merch or reserve your fish to be picked up at local swaps in the Chicago area: https://www.primetimeaquatics.com aquariumhobby #fishkeeping #fishtank #aquarium #petfish
Could life survive in oceans that eat glass and treat water as poison? Explore fluorine-rich biology, hydrogen fluoride seas, and alien creatures whose metabolisms resemble carefully contained rocket engines.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurCheck out TierZoo Remastered: https://nebula.tv/tierzoo/tierzoo-remastered?ref=isaacarthur
Could life survive in oceans that eat glass and treat water as poison? Explore fluorine-rich biology, hydrogen fluoride seas, and alien creatures whose metabolisms resemble carefully contained rocket engines.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurCheck out TierZoo Remastered: https://nebula.tv/tierzoo/tierzoo-remastered?ref=isaacarthur
The world can't create more farmland, but it does need to feed more people. From AI-powered cattle collars and autonomous robots to precision irrigation and gene-edited crops, this episode explores the technologies transforming agriculture. Bryce & Ren unpack why AgTech could become one of the defining investment themes of the next decade, the companies leading the charge, and the risks investors need to understand before backing the future of farming.In this episode: 00:00 – Why agriculture is one of the decade's biggest opportunities 03:47 – Agricultural innovation & feeding a growing population 05:41 – AI, robotics & smart farming transform the paddock 13:19 – Genetics, CRISPR & the next generation of high-yield crops 15:57 – Cold chains: the overlooked technology reducing food waste 17:52 – The biggest risks facing agriculture and AgTech investors 25:31 – Companies & ETFs investing in the future of agriculture 31:55 – Final thoughts: where investors should look for opportunityStocks & ETFs Mentioned: John Deere (NYSE: DE), Kubota (TSE: 6326), Trimble (NASDAQ: TRMB), Corteva Agriscience (NYSE: CTVA), Bayer (XETRA: BAYN), Betashares Global Agriculture ETF (ASX: FOOD), VanEck Agribusiness ETF (NYSE: MOO), iShares MSCI Global Agriculture Producers ETF (NYSE: VEGI), Global X AgTech & Food Innovation ETF (NASDAQ: KROP)This episode of Equity Mates - The Decade Ahead is brought to you by ANZ Business Start Right https://www.anz.com.au/business/business-hub/starting-business/start-right/———Want to get involved in the podcast? Record a voice note or send us a messageAnd come and join the conversation in the Equity Mates Facebook Discussion Group.———Want more Equity Mates? Across books, podcasts, video and email, however you want to learn about investing – we've got you covered.Keep up with the news moving markets with our daily newsletter and podcast (Apple | Spotify)We're particularly excited to share our latest show: Basis PointsListen to the podcast (Apple | Spotify)Watch on YouTubeRead the monthly email———Looking for some of our favourite research tools?Download our free Basics of ETF handbookOr our free 4-step stock checklistFind company information on TIKRResearch reports from Good ResearchTrack your portfolio with Sharesight———This podcast is intended for education and entertainment purposes only. Any advice is general advice and has not taken into account your personal financial circumstances. Before acting on general advice, you should consider if it is relevant to your needs. If unsure, speak to a financial professional. The host of this podcast and their guests may have positions in the companies mentioned. Equity Mates Media is part of the Betashares Group but maintains editorial independence and operates under Australian Financial Services licence 540697. Hosted on Acast. See acast.com/privacy for more information.
Guests:Charlotte Blease, Philosopher at Uppsala University and author of ‘Dr Bot: Why Doctors Can Fail Us – and How AI Could Save Lives'Kevin Mitchell, Associate Professor of Genetics and Neuroscience at Trinity College Dublin and author of ‘Free Agents – How Evolution Gave Us Free Will'Alan Smeaton, Professor of Computing at DCUMatthew Campbell from TCDLaura Hayes, DIAS
Not So: This Week Fred Williams and Doug McBurney review a number of the "not so old things" Bob Enyart compiled over the years in RSR's 2nd Real Science Radio Teaching Book "The List of Not So Old Things." * August is Telethon Month! Go to our store, buy some biblically oriented science material and sponsor a show to help RSR stay on the radio in Denver, and advocating the Biblical truths of creation and salvation on Youtube! * In The Beginning: Order your 9th edition of Walt Brown's amazing, enlightening, biblically-sound book explaining why Earth (and the solar system) look the way they do! * Sun Puzzles: Check out another one of Ellen McHenry's intriguing and enlightening books: Sun Puzzles - on all the curious facts about the Sun that point to an electric, (and not a nuclear) sun. * Jesus Light & Design: Get the first in our series of Real Science Radio Teaching Books, all about how light and design point to Jesus Christ as the Creator and Savior of the world. Not So: Pick up a copy or two of RSR's 2nd in our series of Real Science Radio Teaching Books: "The List of Not So Old Things.," with all the "not so old things" Bob Enyart compiled over the years!
Send us Fan MailA lot of researchers quietly struggle with the same question: when is a study truly ready to publish, and how do you write it so someone actually uses it? From the AVMA Convention 2026, we sit down live with Dr. Joshua Stern, a veterinary cardiologist and geneticist whose work bridges cardiovascular disease, genomics, and clinical impact.We start with Joshua's path into cardiology, sparked by working with “super athlete” animals like racehorses and sled dogs, then move into what he learned from publishing early in his career, including a genetic screening project in boxer dogs that came back completely negative. The twist: those results still mattered, and they taught him how to frame significance, define impact, and tell the truth clearly without overselling. We also talk about how to decide when to stop collecting “just one more” datapoint and instead share findings that can help patients, clinicians, and other researchers now.From there, we get practical about scientific writing and peer review. We unpack how to distill complex datasets into an approachable manuscript, when to move tables and niche analyses into supplementary materials, and why a massive supplement can be a sign you're trying to write two papers. Joshua also shares his go-to mindset for reviewing and responding to reviews, including the simple habit of reading critiques, walking away, and coming back with a clearer lens. We close with a research challenge he hopes the field tackles next: the optimal timing of medical or surgical intervention in dogs and cats as advanced therapies expand.If you care about veterinary research, manuscript publishing, and clinician-scientist career skills, subscribe, share this with a colleague, and leave us a review with your biggest peer review lesson.INTERESTED IN SUBMITTING YOUR MANUSCRIPT TO JAVMA ® OR AJVR ® ?JAVMA ® : https://avma.org/JAVMAAuthorsAJVR ® : https://avma.org/AJVRAuthorsFOLLOW US:JAVMA ® :Facebook: Journal of the American Veterinary Medical Association - JAVMA | FacebookInstagram: JAVMA (@avma_javma) • Instagram photos and videosTwitter: JAVMA (@AVMAJAVMA) / Twitter AJVR ® : Facebook: American Journal of Veterinary Research - AJVR | FacebookInstagram: AJVR (@ajvroa) • Instagram photos and videosTwitter: AJVR (@AJVROA) / TwitterJAVMA ® and AJVR ® LinkedIn: https://linkedin.com/company/avma-journals
If a Mount Rushmore of Epidemiology were to exist, Joseph F. Fraumeni Jr. would be etched into the face of the mountain, former NCI Director Ned Sharpless once told Stephen J. Chanock. Of the hundreds of scientists Fraumeni mentored, perhaps one of the closest was Stephen J. Chanock, his successor as director of the NCI Division of Cancer Epidemiology and Genetics, who worked with Fraumeni for 25 years. Fraumeni died on June 22. He was 93. Otis Brawley, co-editor of the Cancer History Project and the Bloomberg Distinguished Professor of Oncology and Epidemiology at Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, interviewed Chanock on the most recent episode of the Cancer History Project podcast. Brawley and Chanock looked back on Fraumeni's 50-year long career. His contributions to science included co-discovering the Li-Fraumeni syndrome and developing cancer maps, which visualize cancer rate data from every county in the U.S. His work served as a backbone for other major discoveries, such as the two-hit hypothesis by Alfred Knudson and BRCA genes.Fraumeni developed theories around how cancer works and tested them. “The mission statement of DCEG has been to understand the etiology of cancer through epidemiology and genetics as a means to prevention or early intervention,” Chanock said. “That's really the wisdom of Joe Fraumeni who lived that, and really developed the tools, the capabilities, and the workforce to pursue that.”As a result, Fraumeni established a vision of cancer's genetic susceptibility. His observations about diethylstilbestrol raised “a very revolutionary idea” that early exposures could result in precancerous conditions and develop into cancers decades later. The cancer maps added a new attention to cancer caused by environmental exposures. “These patterns were very important, which led to understandings about what was going on post-World War II and [how] certain occupations are associated with select cancers,” Chanock said. “This led to the birth of a whole set of cohorts and case control studies to look at asbestos, smelters, occupational hazards and smokeless tobacco use in the South.” The goal was always to help patients, many of whom had no options at the start of Fraumeni's career. “What Joe was envisioning was the more we understand, the more we can be honest and explain to our patients who develop cancer or may develop cancer, what we could be done to prevent or decrease that risk,” Chanock said. A transcript of this conversation, along with an archive of related content, is available on the Cancer History Project: https://cancerhistoryproject.com/article/joseph-f-fraumeni-jr/
Can you survive inside a star? The answer is stranger than “no.” Explore plasma storms, red giants, magnetic shields, and how future civilizations might turn stars into fortresses.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurWatch my exclusive video Colonizing Ocean Worlds: https://nebula.tv/videos/isaacarthur-colonizing-ocean-worlds-subaquatic-settlementsCheck out Gods & Monsters: https://nebula.tv/curiousarchive/gods-and-monsters?ref=isaacarthur
Can you survive inside a star? The answer is stranger than “no.” Explore plasma storms, red giants, magnetic shields, and how future civilizations might turn stars into fortresses.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurWatch my exclusive video Colonizing Ocean Worlds: https://nebula.tv/videos/isaacarthur-colonizing-ocean-worlds-subaquatic-settlementsCheck out Gods & Monsters: https://nebula.tv/curiousarchive/gods-and-monsters?ref=isaacarthur
In this conversation, Dr. Gladden and Annelie Smith explore the intersection of genetics and nutrition, emphasizing the importance of personalized approaches to health. They discuss the evolution of nutrigenomics, the role of AI in developing tailored health plans, and the complexities of hormonal balance as influenced by genetics. Annelie shares insights from her clinical experience, highlighting the need for a systems biology approach to understand the intricate relationships between genes, hormones, and overall health. The discussion also touches on future directions in genetic testing and the potential for more accessible and actionable insights for individuals. In this conversation, Dr. Gladden and Annelie Smith delve into the complexities of hormone replacement therapy, emphasizing the importance of understanding hormonal pathways and the role of genetics. They discuss how stress impacts hormonal balance and the significance of reprogramming the nervous system for better health outcomes. The conversation also highlights the relevance of nutrigenomics in personalized nutrition and the powerful benefits of sulforaphane. Finally, they explore the value of genetic testing for optimizing health and wellness. For Audience Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/! Takeaways · Nutrigenomics provides insights into personalized nutrition. · Understanding genetics can enhance dietary recommendations. · AI is transforming the landscape of personalized medicine. · Systems biology offers a holistic view of health. · Patient engagement is key to successful health interventions. · Genetic testing can reveal vulnerabilities in health. · Hormonal balance is influenced by genetic factors. · Personalized health plans can improve patient outcomes. · The future of genetics holds promise for broader applications. · Access to genetic information can empower individuals. Hormone replacement therapy is complex and requires a systems approach. · Understanding genetic pathways is crucial for effective hormone management. · Stress significantly impacts hormonal balance and overall health. · Reprogramming the nervous system can alleviate stress and improve health. · Nutrigenomics plays a vital role in personalized nutrition. · Sulforaphane is a powerful compound with numerous health benefits. · Diet should be tailored to the individual, not a one-size-fits-all approach. · Genetic testing provides valuable insights for health optimization. · Managing stress involves rebuilding mental constructs that generate it. · Investing in genetic testing is a one-time opportunity with lasting benefits. Chapters 00:00 Introduction to Nutrigenomics and Personalization 02:49 The Role of Genetics in Nutrition 06:01 Systems Biology Approach to Health 08:55 AI in Nutrigenomics and Personalized Medicine 11:51 Case Study: Hormonal Balance and Genetics 14:59 Future Directions in Genetics and Health 23:35 Understanding Hormone Replacement Therapy 26:16 The Complexity of Hormonal Pathways 28:26 The Role of Stress in Hormonal Balance 30:22 Reprogramming the Nervous System 32:37 Nutrigenomics and Personalized Nutrition 36:27 The Power of Sulforaphane 39:04 Exploring Genetic Testing for Health Optimization To learn more about Annelie Smith:Email: annelie@3X4.io Website: www.3X4Genetics.com Reach out to us at: Website: https://gladdenlongevity.com/ Facebook: https://www.facebook.com/Gladdenlongevity/ Instagram: https://www.instagram.com/gladdenlongevity/?hl=en LinkedIn: https://www.linkedin.com/company/gladdenlongevity YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw
Yo, yo, yo...what's up all you stoners! Mr. and Mrs. Weedman are back with another round of the latest cannabis news, medical marijuana research, industry updates, and a few stories that'll make you stop and say, "Wait...what?"Before diving into the headlines, the duo kicks back for a sesh and then they break down some fascinating new cannabis science. This week they discuss groundbreaking research on cannabinoids as potential antimicrobial agents, a federal study showing teen marijuana use continues to decline even as more states legalize cannabis, and new findings revealing how CBD is helping cancer survivors manage pain, sleep issues, and emotional distress. They also explore a federally funded study suggesting cannabis may help people reduce opioid use and ease withdrawal symptoms, plus why preserving elite cannabis genetics could be the industry's most valuable investment.Light one up, hang out with The Weedman 420 Chronicles Podcast, and enjoy the conversation as they continue their mission to #StompTheStigma and #FreeThePlant.
Recorded at the Battle of Ideas festival 2025 on Sunday 19 October at Church House, Westminster. ORIGINAL INTRODUCTION The past 20 years have seen astonishing advances in science, technology and medicine. Building upon the completion of the Human Genome Project at the turn of the century, scientists have developed ever more powerful ways to sequence and study DNA, enabling us to better understand genetic diseases and develop pioneering treatments. Now, AI tools such as the AlphaFold program developed by Google DeepMind are also providing unprecedented understanding of the human proteome – the complete set of proteins made from instructions in our DNA. As well as acquiring powerful ways to study DNA, we have also acquired powerful ways to change it. CRISPR genome editing, which enables us to make precise changes to the DNA of humans and other organisms, is now widely used in laboratories across the world and has been used in life-saving treatments for devastating diseases. Meanwhile, stem-cell research has advanced to the point where it is now possible to create structures resembling early human embryos entirely from stem cells, instead of having to begin by fertilising an egg cell with a sperm cell. There is even speculation about one day being able to bypass pregnancy altogether. Some are thrilled about the new possibilities opened up by these developments, while others worry about human life being mechanised in ways that seem distasteful. Genetics, genomics, neuroscience and psychology can be (mis)used to seek to reduce human beings to brain circuits and physiological mechanisms, which can then be managed via modification, drugs or nudge-based policy. Who gets to decide what counts as progress, and who gets a say in how science is governed? What happens when the (in)famous Silicon Valley dictum ‘Move fast and break things' meets biology? What can be learned from incidents such as the He Jiankui scandal of 2018, in which a Chinese scientist who worked on human embryos in secret breached scientific and ethical standards, resulting in the birth of three children with edited genomes? How can oversight and rules be imposed, when the science is so complex and fast-moving, and when the world is made up of diverse (and in some cases warring) nation states? Over the past two decades, Sandy Starr of the Progress Educational Trust and Dr Stuart Derbyshire of the National University of Singapore have been involved in numerous national and international deliberations on science, ethics, policy and law in these areas. At this breakfast banter, they will compare their experiences, exchange insights and invite questions. DISCUSSANTS Dr Stuart Derbyshire associate professor, deputy head of psychology, National University of Singapore Sandy Starr deputy director, Progress Educational Trust; author, AI: Separating Man from Machine
My testosterone is 312 ng/dL. By most standards, that's low. But instead of panicking, I sat down and asked myself a simple question: is it actually a problem? In this episode, I walk through my own testosterone journey from TRT and hCG to where I've landed today, and why I'm not rushing to fix a number just because it's low. I look at the tradeoffs I've noticed between higher and lower T: appetite, libido, resting heart rate, HRV, even risk-taking. I also lay out the honest self-assessment I think everyone should run before reaching for a prescription: are your energy, strength, body composition, and drive actually suffering, or are you just reacting to a lab result? This isn't a case against TRT. It's a case for knowing why you're doing it before you start. Thank you to this episode's sponsor, Peluva! Peluva makes minimalist shoes to support optimal foot, back and joint health. I started wearing Peluvas several months ago, and I haven't worn regular shoes since. I encourage you to consider trading your sneakers or training shoes for a pair of Peluvas, and then watch the health of your feet and lower back improve while reducing your risk of injury. To learn more about why I love Peluva barefoot shoes, check out my in-depth review: https://michaelkummer.com/health/peluva-review/ And use code MICHAEL to get 10% off your first pair: https://michaelkummer.com/go/peluva Learn More: 32: Testosterone Replacement Therapy: The One Downside Nobody Talks About: https://www.primalshiftpodcast.com/32-testosterone-replacement-therapy-the-one-downside-nobody-talks-about/ 65: Why Testosterone Affects Your Drive to Do Hard Things: https://www.primalshiftpodcast.com/65-why-testosterone-affects-your-drive-to-do-hard-things/ 83: Understanding Testosterone Production: https://www.primalshiftpodcast.com/83-understanding-testosterone-production/ In this episode: 00:00 Intro 00:53 TRT journey and exit 02:27 Do symptoms even matter 03:51 Honest self-assessment 05:41 High T tradeoffs 06:52 Heart metrics and HRV 08:03 Risk taking and aging 10:03 Lifestyle limits and costs 12:48 Genetics and final thoughts Find me on social media for more health and wellness content: Website: https://michaelkummer.com/ YouTube: https://www.youtube.com/@MichaelKummer Instagram: https://www.instagram.com/primalshiftpodcast/ Pinterest: https://www.pinterest.com/michaelkummer/ Twitter/X: https://twitter.com/mkummer82 Facebook: https://www.facebook.com/realmichaelkummer/ [Medical Disclaimer] The information shared on this video is for educational purposes only, is not a substitute for the advice of medical doctors or registered dietitians (which I am not) and should not be used to prevent, diagnose, or treat any condition. Consult with a physician before starting a fitness regimen, adding supplements to your diet, or making other changes that may affect your medications, treatment plan, or overall health. [Affiliate Disclaimer] I earn affiliate commissions from some of the brands and products I review on this channel. While that doesn't change my editorial integrity, it helps make this channel happen. If you'd like to support me, please use my affiliate links or discount code.
The Menopause Mastery Show | DNA Is Not Destiny: The Future of Personalized Menopause Care | Episode 289 with Tracy Wood
Tiny Expeditions - A Podcast about Genetics, DNA and Inheritance
This episode tells the story of one superstar peanut from the Wiregrass Peanut Project and how it could change the game for the peanut industry in south Alabama. To go behind the scenes and learn more about this episode, visit “Paging Bruce: The connection between a local student and a peanut in Puerto Rico.” If you prefer to watch your podcasts, head over to Youtube at https://www.youtube.com/watch?v=KR5iH59Y_W4. Thanks for listening! We're now on YouTube- follow us here. To receive episode updates and bonus material, subscribe to our mailing list here.
Carika Weldon, Founder and CEO of CariGenetics, shares her mission to bring genetic research expertise and equipment to the Caribbean.
New partnerships Rice ‘N Grinds (Pride Foods) – 10% off w/ code TTMMegaFit Meals - 10% off w/ code TTMToday's Topics:00:00:00 - Intro00:02:40 - Bucket List Golf Courses 00:06:03 - ODA Time Away From Home 00:08:19 - Nicotine for Focus 00:14:14 - Balancing Golf and Training 00:19:04 - Belt Squat Attachments vs. Pit Shark 00:22:54 - Favorite Army Schools 00:32:04 - Genetics vs. Hard Work 00:37:26 - Two Leg Days Per Week 00:43:45 - Carb Intake on High-Training Days 00:48:12 - MOS and Group Selection 00:51:06 - Long Irons vs. Hybrids 00:52:42 - Treadmill Running in Extreme Heat 00:53:37 - High-Frequency Lifting Programs 00:58:33 - Running Faster at 215 Pounds 01:01:19 - 400s and 800s for Faster Runs 01:06:35 - Favorite European SOF Units 01:09:32 - Daily Step Count 01:12:50 - Carb Loading Before Long Runs 01:15:21 - Ideal Body Weight for Selection 01:18:09 - Tempo Run Warm-Up and Cool-Down 01:20:29 - Chips and Salsa Every Day? 01:21:05 - Push-Pull-Legs for Better Running—Questions? Look for bi-weekly Q&A on my stories. I'll answer your questions on IG and here on the podcast.—New SFAS Program (includes 59-page SFAS Personal Dev Guidebook) New Running Program: TTM Run AdvancedNew Selection Prep Program: Ruck | Run | Lift New Hybrid Program: Jacked Gazelle 3.0Ebook: SOF Selection Recovery & Nutrition Guide—TrainHeroic Team Subscription: T-850 Rebuilt (try a week for free!)—PDF programs2 & 5 Mile Run Program - run improvement program w/ strength workKickstart- beginner/garage gym friendlyTime Crunch- Workouts for those short on timeHypertrophy- intermediate/advancedJacked Gazelle- Hybrid athleteJacked Gazelle 2.0 - Hybrid athlete—Spoken Supplements: Code terminator_trainingCwench supplements: Code terminator_training—Let's connect:Newsletter Sign UpIG: terminator_trainingYoutubeWebsiteSubstack
Submit your question and we'll answer it in a future episode!Join our Patreon Community!https://www.patreon.com/badassbreastfeedingpodcastSPONSOROriginal Sprout. Original Sprout carries safe and effective styling, body and hair care products that are safe for babies and great for adults. Use code BADASS26 at www.originalsprout.com for 25% off of your purchase.Today, Dianne and Abby are re-visiting the whole idea that breastfeeding gives your baby cavities. Is it true? Is it myth? Listen in today to see what the research says about cavities, breastfeeding and good old genetics.If you are a new listener, we would love to hear from you. Please consider leaving us a review on iTunes or sending us an email with your suggestions and comments to badassbreastfeedingpodcast@gmail.com. You can also add your email to our list and have episodes sent right to your inbox!Things we talked about:Spotify comments [10:38]Comment from Dr. Jay Gordon (The tree branch…) [14:00]The research [14:50]The sugars [17:00]Inconsistent information [19:50]Genetics and cavities [22:50]Other foods contribute [28:18]Milk does not sit on the teeth [28:30]The ADA stance on breastfeeding [32:13]Things we talked about or Episodes we think you should check out!https://badassbreastfeedingpodcast.com/episode/breastfeeding-myths-we-found-on-the-internet/https://badassbreastfeedingpodcast.com/episode/medical-info-to-flush-down-the-toilet/Set up your consultation with Diannehttps://badassbreastfeedingpodcast.com/consultations/ Check out Dianne's blog here:https://diannecassidyconsulting.com/milklytheblog/ Follow our Podcast:https://badassbreastfeedingpodcast.comHere is how you can connect with Dianne and Abby:AbbyTheuring ,https://www.thebadassbreastfeeder.comDianne Cassidy @diannecassidyibclc, http://www.diannecassidyconsulting.comMusic we use:Music: Levels of Greatness from We Used to Paint Stars in the Sky (2012) courtesy of Scott Holmes at freemusicarchive.org/music/ScottHolmes
Disclaimer: Today's episode is sponsored by Nurp. Content is for educational purposes only. Not advice. Results discussed have not been vetted. Claims made by the guest have not been verified. The views expressed by the guest do not reflect those of the host or this show.—
We love to hear from our listeners. Send us a message. On this week's episode of the Business of Biotech, Aris Baras, M.D., SVP, Head of Regeneron Genetics Center (RGC) and Co-Head of Regeneron Genetic Medicines, talks about using large-scale human genetics to find better drug targets based on "superhuman" variants. Aris explains how multi-omics, linked health records, and AI are helping developers move faster in the clinic and reduce the odds of failure, while also pushing biotech toward earlier disease prediction and more preventive care. Access this and hundreds of episodes of the Business of Biotech videocast under the Business of Biotech tab at lifescienceleader.com. Subscribe to our monthly Business of Biotech newsletter. Get in touch with guest and topic suggestions: ben.comer@lifescienceleader.comFind Ben Comer on LinkedIn: https://www.linkedin.com/in/bencomer/
APR Health Solutions Peptides: www.aprhealthsolutions.com - code nyleOptimize HRT Clinic: https://members.optimize-hp.com - code nyleMerch: https://www.aykons.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'nyle' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘nyle' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program: https://www.nylenaygafitness.comRP Hypertrophy Training App: rpstrength.com/nyle (code nyle)00:00:00 Intro00:00:42 Relationships & Marriage00:04:48 Identity - “You Are Not Bodybuilding”00:6:57 Finding Faith00:14:38 The Origin Story00:20:39 Starting Gear as a Teen00:28:17 The Tragic 2016 NY Pro00:39:34 Honoring Lost Loved Ones00:48:11 Peptides & Health00:50:00 Remembering Ryan00:52:32 Training Regrets & 4-Day Splits00:58:18 Managing the Off-Season01:04:15 Designing an Off-Season Cycle01:16:30 Pharma vs. Generic GH01:25:31 Does GH Cause Distension?01:30:31 PEDs to Avoid01:32:25 Peptides That Actually Work01:37:38 GLP-1s in Bodybuilding01:44:51 Post-Show Rebound Strategies01:48:35 Orals at the End of Prep01:52:05 Genetics in Open Bodybuilding01:57:13 Genetic Testing for Athletes01:59:29 Building Huge Hamstrings02:04:35 Deloading vs. Total Rest02:05:36 Organ Health Supplements02:07:14 Bodybuilding & Relationships02:08:35 Underrated Prep Foods02:09:37 Final Message to the World
Send us Fan MailAdvocating for your own health ~ support through menopause, thyroid & hormones.Cindy Dupuie is a functional medicine nutritionist who now focuses on perimenopause & menopause, helping women become their own advocate for their health.She likes to help women with diabetes, thyroid issues, HRT, digestion & weight loss.We discuss how hormonal changes can have an effect on women as they age, with issues such as anxiety, and the importance of oestrogen for the body. Connect with Cindy:Instagram @cindy_dupuie Video: What End Is Up When It Comes To HRT https://youtu.be/A-jMfvQifjoYouTube channel Signature Course: Grace In Transition for Women Of A Certain Age https://alivingbalance.net/course/Free Download Lab Checklist for The Pause Years https://alivingbalance.net/guide-to-essential-lab-work-download-page/ Hair & Scalp Salon Specialist course Support the showConnect with Hair therapy:FacebookInstagramTwitterClubhouse- @Hair.TherapyHair Therapy WebsiteDonate towards the podcast Start your own podcastHair & Scalp Salon Specialist Course ~ Book now to become an expert!
Send us Fan MailI'm Bridget Walton, a functional nutritionist helping ambitious women ages 25-45 naturally restore hormone balance, fix irregular periods, feel confident in their fertility, and resolve gut health issues without restrictive dieting.If you struggle with missing periods, PMOS/PCOS symptoms, bloating, or unpredictable cycles, this women's health podcast will teach you how to support your hormones through strategic nutrition and lifestyle changes that actually fit your busy life.On I'm Hormonal, you'll discover natural solutions for period problems, learn how gut health impacts your hormones, and get practical hormone balance tips from a functional nutrition perspective - no more guessing what your body needs.Today's episode is an interview with Leah Vong where you'll learn about the connection between hormone balance and genetics. In her client work, Leah uses genetic testing to help women get clear on their path to balance in wellness. You'll learn about the nutrition and lifestyle shifts that you can make in order to support your best health and how those decisions influence your gene expression.Learn more about Leah's work: www.leahvong.com Free download: How to Identify Your Food Triggers
The Moon may be dusty and desolate, but its future could be full of traffic. In this extended edition, we explore how mass drivers, rockets, space elevators, and orbital logistics could turn the Moon into the industrial gateway of the Solar System.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurWatch Mad Kings: https://nebula.tv/madkings?ref=isaacarthurVisit our Website: http://www.isaacarthur.netJoin Nebula: https://go.nebula.tv/isaacarthurSupport us on Patreon: https://www.patreon.com/IsaacArthurSupport us on Subscribestar: https://www.subscribestar.com/isaac-arthurFacebook Group: https://www.facebook.com/groups/1583992725237264/Reddit: https://www.reddit.com/r/IsaacArthur/Twitter: https://twitter.com/Isaac_A_Arthur on Twitter and RT our future content.SFIA Discord Server: https://discord.gg/53GAShECredits:Mass Drivers on the Moon: Enabling a Lunar EconomyWritten, Produced & Narrated by: Isaac ArthurEditor: Phil SwanGraphics:Apogii.ukAnthrofuturismJeremy JozwikSergio BoteroPhil SwanSelect imagery/video supplied by Getty Images Music Courtesy of Epidemic Sound http://epidemicsound.com/creatorChapters0:00 Intro0:09 Why the Moon, Why Launch?4:12 Mass Drivers: The Basics and the Vision8:24 Building the Lunar Launch Rail13:15 The Big Advantages: Why Mass Drivers—And Why the Moon?20:09 Challenges and Engineering Considerations28:29 Rockets and Space Elevators: Friends or Rivals?31:06 The Logistics Web of the Moon32:30 The Roadmap: From Testbed to Trade Empire34:28 Mad Kings35:35 The Moon as Our First Cosmic Freight TerminalSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
The Moon may be dusty and desolate, but its future could be full of traffic. In this extended edition, we explore how mass drivers, rockets, space elevators, and orbital logistics could turn the Moon into the industrial gateway of the Solar System.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurWatch Mad Kings: https://nebula.tv/madkings?ref=isaacarthurVisit our Website: http://www.isaacarthur.netJoin Nebula: https://go.nebula.tv/isaacarthurSupport us on Patreon: https://www.patreon.com/IsaacArthurSupport us on Subscribestar: https://www.subscribestar.com/isaac-arthurFacebook Group: https://www.facebook.com/groups/1583992725237264/Reddit: https://www.reddit.com/r/IsaacArthur/Twitter: https://twitter.com/Isaac_A_Arthur on Twitter and RT our future content.SFIA Discord Server: https://discord.gg/53GAShECredits:Mass Drivers on the Moon: Enabling a Lunar EconomyWritten, Produced & Narrated by: Isaac ArthurEditor: Phil SwanGraphics:Apogii.ukAnthrofuturismJeremy JozwikSergio BoteroPhil SwanSelect imagery/video supplied by Getty Images Music Courtesy of Epidemic Sound http://epidemicsound.com/creatorChapters0:00 Intro0:09 Why the Moon, Why Launch?4:12 Mass Drivers: The Basics and the Vision8:24 Building the Lunar Launch Rail13:15 The Big Advantages: Why Mass Drivers—And Why the Moon?20:09 Challenges and Engineering Considerations28:29 Rockets and Space Elevators: Friends or Rivals?31:06 The Logistics Web of the Moon32:30 The Roadmap: From Testbed to Trade Empire34:28 Mad Kings35:35 The Moon as Our First Cosmic Freight TerminalSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Thank you for watching!~CHECK OUT ALL THE LINKS BELOW FOR THE SYNDICATE & RIOT Co.!https://link.me/breederssyndicate~SUPPORT the channel or JOIN the Discord community: https://www.buymeacoffee.com/matthewriot (This channel is not monetized - any contributions are warmly appreciated & keep us going)~QUALITY GEAR (shirts, stickers, beanies, mugs etc): https://breeders-syndicate-shop.fourthwall.com~PLANT HEALTH & SEX TESTING: https://www.farmerfreeman.com (Coupon Code: SYNDICATE5 )
Thank you for watching!~CHECK OUT ALL THE LINKS BELOW FOR THE SYNDICATE & RIOT Co.!https://link.me/breederssyndicate~SUPPORT the channel or JOIN the Discord community: https://www.buymeacoffee.com/matthewriot (This channel is not monetized - any contributions are warmly appreciated & keep us going)~QUALITY GEAR (shirts, stickers, beanies, mugs etc): https://breeders-syndicate-shop.fourthwall.com~PLANT HEALTH & SEX TESTING: https://www.farmerfreeman.com (Coupon Code: SYNDICATE5 )
* Special Delivery: A meteorite got the attention of hosts Fred Williams and Doug McBurney , because it had so many characteristics predicted by Hydroplate theory, (and it smashed through a guy's roof in New Jersey!) which got everybody's attention! * Midwest Creation Fellowship: Hear about Fred's talks at the Midwest Creation Fellowship in Chicago! * Chemicals Between Us: Find out if the discovery of sugar in space is evidence of the origin of life without the God of Abraham, Isaac & Jacob. * In The Beginning: Pre-order the 9th edition of Walt Brown's amazing, enlightening, biblically sound book explaining why Earth (and the solar system) look the way they do! * Sun Puzzles: Check out another one of Ellen McHenry's intriguing and enlightening books: Sun Puzzles - on all the curious facts about the Sun that point to an electric, (and not a nuclear) sun. * Sponsor a Show! Go to our store, buy some biblically oriented science material and sponsor a show! * Jesus Light & Design: Get the first in a series of Real Science Radio Teaching Books all about how light and design point to Jesus Christ as the Creator and Savior of the world.
Osteosarcoma Webinar Series: Dr. Jing Huang is a Senior Investigator and Head of the Cancer and Stem Cell Epigenetics Group in the Laboratory of Cancer Biology and Genetics at the National Cancer Institute (NCI). He received his bachelor's degree in Biochemistry from Peking University and his Ph.D. in Biochemistry and Biophysics from the University of Rochester, followed by postdoctoral training in cancer epigenetics at the Wistar Institute.Dr. Huang joined the NCI as a Principal Investigator in 2008 and earned tenure in 2016. His laboratory investigates transcriptional and epigenetic regulation in cancer and stem cells, with a major focus on the oncogenic driver RUNX2 in osteosarcoma. His ultimate goal is to develop novel therapeutic strategies and translate laboratory discoveries into clinical advances for osteosarcoma patients.
What if the future of industry isn't giant factories, but molecular machines too small to see? DNA factories could repair bodies, grow habitats, and transform civilization.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurWatch my exclusive video Colonizing Ocean Worlds: https://nebula.tv/videos/isaacarthur-colonizing-ocean-worlds-subaquatic-settlementsCheck out Gods & Monsters: https://nebula.tv/curiousarchive/gods-and-monsters?ref=isaacarthur
What if the future of industry isn't giant factories, but molecular machines too small to see? DNA factories could repair bodies, grow habitats, and transform civilization.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurWatch my exclusive video Colonizing Ocean Worlds: https://nebula.tv/videos/isaacarthur-colonizing-ocean-worlds-subaquatic-settlementsCheck out Gods & Monsters: https://nebula.tv/curiousarchive/gods-and-monsters?ref=isaacarthur
At Lifespan, our mission is to help you and your loved ones live your longest, healthiest lives while supporting medical research into breakthroughs to improve all lives. We're building the world's largest longevity community: Join us at https://lifespan.com. Follow us on YouTube, Apple, and Spotify for new Lifespan episodes every 2 weeks. __________________________________________ In this episode of Lifespan, Dr. David Sinclair, A.O., Ph.D. – Professor of Genetics at Harvard Medical School and pioneer in longevity research – explores the science of eye aging, vision loss, and emerging strategies to preserve vision throughout life. Dr. Sinclair shares an exclusive update on ER-100, including his team's successful restoration of vision in non-human primates and the launch of the world's first FDA-cleared age reversal human clinical trial. This Phase 1 clinical trial will evaluate the safety of epigenetic cellular restoration as a therapy. Additionally, drawing on decades of research, Dr. Sinclair explains why the eyes may offer one of the earliest windows into biological aging, how everyday factors such as sleep position, alcohol consumption, and intraocular pressure influence long-term eye health, and what the latest evidence reveals about nutrition, supplements, and the connection between the eyes and the brain. Whether you're interested in longevity, brain health, or protecting your eyesight, this episode provides an evidence-based look at the biology of vision and the future of regenerative medicine. __________________________________________ Partners of the Lifespan show help us keep this program freely available as an educational resource while also supporting medical research. We only collaborate with partners whose products are grounded in science and that our team has personally used for years. Our selected partners make it convenient for the Lifespan audience to access the tools and technologies featured in this episode - from exogenous fuel for neurons (Ketone-IQ), to wearables that track recovery, strain, and sleep (WHOOP), to smart devices that measure key health metrics such as visceral fat and muscle mass (Withings). If you'd like to learn more or try these tools: ○ Ketone-IQ: Get 30% off your first monthly order at https://ketone.com/lifespan or with code LIFESPAN ○ WHOOP: Get a free WHOOP band and one month of membership at https://join.whoop.com/LIFESPAN or with code LIFESPAN ○ Withings: Get 10% off smart health devices at https://withings.com/lifespan or with code LIFESPAN __________________________________________ Legal & Medical Disclaimers The Lifespan show and all related content are provided for informational and educational purposes only and are not intended as medical advice, diagnosis, or treatment. Nothing presented should be interpreted as a recommendation to diagnose, treat, cure, or prevent any disease or medical condition. This content is not a substitute for professional medical advice, diagnosis, or treatment from a qualified healthcare provider. You should always consult with a licensed physician or other qualified healthcare professional before making decisions about your health, including starting, stopping, or modifying any treatment, supplement, diet, or exercise program. The information shared reflects the views and opinions of the host and guests and is based on the scientific literature, their experience and expertise, and general wellness principles. Listening to or engaging with Lifespan content does not establish a doctor–patient or clinical relationship. Health and longevity outcomes can vary significantly between individuals. Any references to studies, interventions, products, or protocols are not guarantees of specific results, and individual responses may differ. From time to time, Lifespan may discuss or partner with third-party products or services. These references are provided for informational purposes only and should not be considered medical recommendations or endorsements of efficacy for any individual. Lifespan Foundation is an independent 501(c)(3) non-profit organization whose mission is to support medical research. The views expressed by Dr. David Sinclair, A.O., Ph.D., are his own and do not represent those of Harvard University, Harvard Medical School, or any affiliated institutions.
0:00 The friend he hasn't seen since sixth grade 5:16 Angelina Jolie, BRCA, and the 20% nobody tells women about 18:23 What a cancer cell actually is - and why tumors evolve 26:31 How cancer actually kills you, and what a seizure is 32:14 The last cigarette: why he can't take the test every week 46:27 The best medicine in the world, and who can't get to it 1:03:23 Telling a family there's nothing left Noam hadn't seen Kenan Onel since high school in Ardsley, where Onel graduated first in the class and Noam, by his own account, drifted somewhere well below. Fifty years later Onel runs genetics and genomics at Roswell Park - the only comprehensive cancer center in all of western New York - and Noam has one thing he wants to ask him about. He's afraid of cancer. His grandfather died of it. His father died of it. He's taken the Grail blood test, it came back clean, and he wants to know why he can't just take it every week. What follows is part reunion and part interrogation. Onel explains what a cancer cell actually is, why tumors evolve like finches in the Galapagos, and what is physically happening to someone during a seizure. He explains how cancer kills - the mechanism, organ by organ. And he tells Noam that the test he's counting on just failed its biggest trial in the UK, which sets off the real argument of the hour: whether a guideline written for a population means anything at all to the one person sitting in the chair. Then, near the end, Noam asks how you tell a family there's nothing left to offer. The answer is the best thing in the episode. Also: the 20% of women who are high-risk and have never been told, the doctor who warned Noam that Pellegrino was bad for his son's bones, a scan booked by 4pm the next afternoon, and one entire podcast without mentioning Israel. Dr. Kenan Onel is Chief of the Division of Genetics and Genomics and Director of the Center for Precision Oncology and Cancer Prevention at Roswell Park Comprehensive Cancer Center. Live from the Table is the official podcast of the world-famous Comedy Cellar.
Dr. Pak Androulakis-Korakakis returns to explain what the research says about the minimum effective dose for muscle growth, strength, health, and long-term physical independence.In this episode, we discuss:• The minimum amount of training required to build muscle• Whether minimum-dose training produces meaningful real-world results• How inactive and metabolically unhealthy people respond to resistance training• Where diminishing returns begin as training volume increases• Minimum effective dose training for everyday people• Minimum-dose training for serious lifters• Whether people accurately estimate reps in reserve• Training close to failure in high and low rep ranges• When you should and should not train to failure• Whether machines are enough for older adults• Building muscle and supporting bone health as you age• Fatigue, recovery, and the reality of overtraining• Genetics and realistic expectations• Why consistency matters more than training secrets• Pak's new book, Train Smarter, Not Longer• And much moreFollow Dr. Pak Androulakis-Korakakis on Instagram:@dr__pakCHAPTERS01:05 Minimum Effective Dose04:34 Research-Based Volume Targets05:48 Training Close to Failure08:27 Fractional Sets Explained11:06 Low- vs. High-Volume Training16:22 Minimum-Dose Training for Real Life20:08 Rep-Range Absolutism26:24 Fatigue and Overtraining Myths30:03 Injury Risk and Training Workarounds32:29 Minimum-Dose Training for Seniors33:21 Results From 20 Minutes Per Week37:11 Machines for Safe, Hard Training38:34 Larry's Recovery Update42:41 Estimating Reps in Reserve45:10 Does Anything Actually Matter?49:18 Genetics and Realistic Expectations53:15 Consistency Beats Training Secrets57:38 Pak's Book and What Comes NextSUPPORT THE SHOWIf this episode helped you rethink how much training is actually required to make progress:• Subscribe and check out more episodes• Share the episode on social media and tag @andrewcoatesfitness• Send it to someone who thinks they do not have enough time to trainFOLLOW ANDREW COATESInstagram: @andrewcoatesfitnesshttps://www.andrewcoatesfitness.comPARTNERS AND RESOURCESRP STRENGTH APPUse code COATESRP:https://www.rpstrength.com/coatesJUST BITE ME MEALSUse code ANDREWCOATESFITNESS for 10% off:https://justbitememeals.comMACROSFIRST — FREE PREMIUM TRIAL• Download MacrosFirst• Begin setting up your account• When asked, “How did you hear about us?” enter: ANDREWKNKG BAGS — 15% OFFhttps://www.knkg.com/Andrew59676VERSA GRIPPShttps://www.versagripps.com/andrewcoatesTRAINHEROIC — FREE 90-DAY TRIAL• Visit: https://www.trainheroic.com/liftfree• Reply to the email you receive or email trials@trainheroic.com• Let them know Andrew sent youL1 BIOMECHANICS AND ASSESSMENT COURSEUse code COATES:https://pro.activelifeprofessional.com/assessmentworkshopevents
Want to live longer?What if getting sick wasn't inevitable?Longevity physician Dr. Gregory Burzynski joins us to explain how modern medicine is shifting from treating disease to preventing it before it starts.We discuss the cutting-edge tests, imaging, genetics, peptides, supplements, hormone therapy, and lifestyle habits that could dramatically improve not just how long you live, but how well you live.We also tackle the biggest misconceptions about aging, why waiting until symptoms appear may be costing you years of healthy life, and which longevity strategies are actually worth your money.In this episode we cover:• The blood tests every woman should know about• Whole-body imaging and early cancer detection• Gene testing vs. epigenetics• Creatine, Vitamin D, fish oil & NMN• HRT and Peptides• Cold plunges, fasting, saunas & wearables• The future of longevity medicineIf you enjoy the episode, don't forget to subscribe, leave a review, and share it with someone who wants to stay healthy for decades to come.Dr. Gregory Burzynski's Links:resTOR longevity Clinic HCM, Houston Concierge Medicine(00:01:03) Why longevity is changing the future of medicine(00:04:00) Why Dr. Gregory Burzynski thinks dying should be optional.(00:09:46) When should you start thinking about longevity?(00:14:00) Do you have to be wealthy to live longer?(00:16:20) The best tests to catch disease before symptoms appear(00:21:28) Genetics vs. epigenetics—what's the difference?(00:24:00) Can we turn back the clock? (00:31:01) Inflammation, supplements & the biggest deficiencies doctors see(00:36:30) Rapamycin, NMN & the future of anti-aging medicine(00:47:38) Peptide use and availability(00:50:22) Lightning Round: Fasting, cold plunges, saunas & alcohol(00:54:41) HRT, testosterone & wearable health trackers(00:59:43) Where to hear more from Dr. Gregory BurzynskiWant to leave the TTSL Podcast a voicemail? We love your questions and adore hearing from you. https://www.speakpipe.com/TheThickThighsSaveLivesPodcastThe CVG Nation app, for iPhoneThe CVG Nation app, for AndroidOur Fitness FB Group.Thick Thighs Save Lives Workout ProgramsConstantly Varied Gear's Workout LeggingsDisclaimer: The information shared in this podcast is for educational and informational purposes only and is not intended as medical advice. The views expressed are those of the hosts and guests and should not be used as a substitute for professional medical diagnosis, treatment, or advice. Always consult your physician or qualified healthcare provider before making changes to your diet, exercise routine, medications, supplements, or healthcare plan.Statements regarding supplements and wellness products have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.Guest opinions are their own and do not necessarily reflect the views of the hosts or producers.
Space colonies may reach the stars… then collapse. From fragile ecosystems to genetic drift and incentive failure, how do new settlements survive long enough to become civilizations?Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurWatch Mad Kings: https://nebula.tv/madkings?ref=isaacarthur
Space colonies may reach the stars… then collapse. From fragile ecosystems to genetic drift and incentive failure, how do new settlements survive long enough to become civilizations?Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurWatch Mad Kings: https://nebula.tv/madkings?ref=isaacarthur
If you've scrolled through your feeds recently, you've probably seen the video that's causing a stir: a prominent infertility doctor sharing her “Hot Take” personal observations on social media, claiming that IUDs are a hidden cause of intrauterine adhesions- or severe uterine scar tissue. Now, Listen. It is completely natural to see a specialist standing in a white coat making a passionate claim and think, "Wow, should I be worried about my birth control?" But here is the reality we need to establish right out of the gate: a handful of individual cases shared online is the very definition of anecdotal evidence. It does not fulfill the criteria of rigorous scientific observation. When we pull back from the algorithm and look at the actual clinical data involving millions of IUD users worldwide, the science shows us something completely different. In fact, large-scale studies demonstrate that IUDs do not cause this scarring—and historically, certain models have actually been used to prevent the uterine walls from sticking together during post-surgical healing. So today, we are separating the scrolling panic from the actual science. We have REA data from the recent FACT (Fertility After Contraceptive Termination) study from 2021 (AJOG). We're breaking down what the data really says, why the internet loves a medical scare, and the true, proven causes of intrauterine adhesions. 1. Abel MK, Wald K, Cedars MI, Noel M. Uterine Synechiae After Intrauterine Device Use: A Case Series. Journal of Assisted Reproduction and Genetics. 2021. 2. Chung E, Wang F, Zhang J, Strug M, Aghajanova L, Lathi R. The impact of prior hormonal intrauterine device (IUD) use on endometrial lining thickness in the fertility clinic setting: a retrospective cohort study. J Assist Reprod Genet. 2026 Jun 25. doi: 10.1007/s10815-026-03950-x. Epub ahead of print. PMID: 42347902.3. Peipert JF, Zhao Q, Schreiber CA, Teal S, Turok DK, Natavio M, Cordon S, Daggy J. Intrauterine device use, sexually transmitted infections, and fertility: a prospective cohort study. Am J Obstet Gynecol. 2021 Aug;225(2):157.e1-157.e9. doi: 10.1016/j.ajog.2021.03.011. Epub 2021 Mar 11. PMID: 33716075.
Why the Transition Period Is a Critical Window for Dairy Cow Health (02:10 – 10:36) The discussion begins by examining the transition period as one of the most challenging phases in a dairy cow's lifecycle. Research suggests that 30–50% of disease events occur within the first three weeks after calving, making this a key window for understanding and supporting immune function. Dr. Rostoll-Cangiano shares insights into the biological changes that occur during this time, emphasizing the importance of immune adaptation as cows move from late gestation into early lactation. Immune Cell Dynamics and Metabolic Stress in Transition Cows (02:10 – 10:36) Building on this foundation, Dr. Rostoll-Cangiano discusses emerging research on T-cells, dendritic cells, and the differences between systemic and intestinal immune responses. The panel explores how immune cells face substantial metabolic demands after calving, often becoming metabolically constrained as they attempt to support both immune defense and milk production. This competition for energy and nutrients may leave cows more susceptible to disease challenges and environmental stressors during the transition period. Dry Period Management and Prepartum Feed Intake (10:36 – 16:26) The conversation then turns to management practices that can influence transition success before calving. The panel examines how changes in dry matter intake (DMI), bunk space availability, and social stress can significantly affect a cow's metabolic health and immune resilience. Maintaining consistent feed intake and minimizing unnecessary stressors during the dry period are highlighted as key strategies for supporting a smoother transition into lactation. Genetics, Productivity, and Cow Resilience (17:52 – 24:44) The group explores whether modern dairy genetics have altered the balance between productivity and resilience. While today's dairy cows produce substantially more milk than previous generations, the panel discusses whether this increased productivity may come with narrower physiological margins under stress. The discussion highlights the ongoing challenge of improving production while preserving the ability of cows to adapt to metabolic and environmental stressors. Factors Affecting Colostrum Quality and Calf Immunity (28:17 – 35:18) Attention then shifts to colostrum production and quality, with a focus on how maternal health before calving can influence calf outcomes. Topics include the effects of: Metabolic status during the transition period Somatic cell count at dry-off Prepartum inflammation Immunoglobulin G (IgG) concentration Passive transfer and calf health The panel explains how these factors can influence both the quality of colostrum and the long-term health and performance of newborn calves.Nutritional Interventions to Support Transition Cow Performance The experts review research evaluating choline and chromium supplementation as potential tools for supporting transition cow health and improving colostrum production. While published responses have been variable, these nutritional strategies continue to receive attention for their potential role in enhancing metabolic function and immune responses around calving. Precision Dairy Technologies for Managing At-Risk Cows (37:27 – 44:51) The conversation expands into activity monitors and rumination tracking systems. These tools allow producers to identify at-risk cows earlier, monitor behavioral changes, and make more informed management decisions at the individual cow level. By detecting potential problems before clinical signs appear, precision technologies can help improve intervention timing and overall herd health outcomes. Key Transition Cow Management Takeaways The episode concludes with a reminder that, despite advances in dairy research and technology, strong management fundamentals remain the most effective way to support cow health and performance: Maximize dry matter intake Reduce stress and unnecessary regrouping Manage body condition score changes Prioritize cow comfort Provide adequate feeding and resting space Ultimately, while the biology of transition cows is complex, the panel emphasizes that the greatest improvements in health, productivity, and resilience often come from consistently executing proven management practices. Join the Real Science Exchange Please subscribe and share with your industry friends. Invite more people to join us at the Real Science Exchange virtual pub table. Please be sure to register for our upcoming Real Science Lecture Series webinars. Finally, if you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription. Then, email a picture to anh.marketing@balchem.com. Include your size and mailing address. As a result, we'll mail you a shirt.
Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas
One of the characteristics of life is that living organisms gather information and put it to use. Even one of the simplest lifeforms, bacteria, are able to sense features of their surroundings and alter their behavior accordingly. Most impressively, they are able to sense the presence of similar bacteria by a process called quorum sensing. Today's guest, Bonnie Bassler, is a leader in this field, and explains how quorum sensing allows groups of bacteria to do things (including in our bodies) that wouldn't be possible for individual bacteria. Blog post with transcript: https://preposterousuniverse.com/podcast/2026/07/20/361-bonnie-bassler-on-how-bacteria-talk-and-work-together/ Support Mindscape on Patreon. Bonnie Bassler received a Ph.D. in biochemistry from Johns Hopkins University. She is currently Andrew K. Golden University Professor of Molecular Biology at Princeton University and a Howard Hughes Medical Institute Investigator. She is a member of the National Academy of Sciences, National Academy of Medicine, and the American Academy of Arts and Sciences. Among her awards are a MacArthur Fellowship, the Gruber Prize in Genetics, and the National Medal of Science. Lab web site Princeton web page Google Scholar publications Wikipedia
Cloning may seem like a futuristic topic largely reserved for science fiction but plants are doing it all the time. Clonality is one of the many aspects that can make plant species successful across the landscape. It can also greatly impact the way we approach plant conservation efforts. Despite the importance of cloning in plants, we still know very little about how its influences plant population dynamics. Which plants are clonal? How long can clones live? How does cloning influence pollination? These questions and more are what drive people like Dr. Ashley Morris. Join us as we look at why she is so fascinated by cloning and conservation in plants. This episode was produced in part by Chris, Gerald, Elise, Maggie, Mamie, A.J., Dallas, Channele, KC, Joe, Diane, Kim, Tanya, Neil, Matthew, April, Dana, Lilith, Sanza, Eva, Yellowroot, Wisewren, Nadia, Heidi, Blake, Josh, Laure, R.J., Carly, Lucia, Dana, Sarah, Lauren, Strych Mind, Linda, Sylvan, Austin, Sarah, Ethan, Elle, Steve, Cassie, Chuck, Aaron, Gillian, Abi, Rich, Shad, Maddie, Owen, Linda, Alana, Sigma, Max, Richard, Maia, Rens, David, Robert, Thomas, Valerie, Joan, Mohsin Kazmi Photography, Cathy, Simon, Nick, Paul, Charis, EJ, Laura, Sung, NOK, Stephen, Heidi, Kristin, Luke, Sea, Shannon, Thomas, Will, Jamie, Waverly, Brent, Tanner, Rick, Kazys, Dorothy, Katherine, Emily, Theo, Nichole, Paul, Karen, Randi, Caelan, Tom, Don, Susan, Corbin, Keena, Robin, Peter, Whitney, Kenned, Margaret, Daniel, Karen, David, Earl, Jocelyn, Gary, Krysta, Elizabeth, Southern California Carnivorous Plant Enthusiasts, Pattypollinators, Peter, Judson, Ella, Alex, Dan, Pamela, Peter, Andrea, Nathan, Karyn, Michelle, Jillian, Chellie, Linda, Laura, Miz Holly, Christie, Carlos, Paleo Fern, Levi, Sylvia, Lanny, Ben, Lily, Craig, Sarah, Lor, Monika, Brandon, Jeremy, Suzanne, Kristina, Christine, Silas, Michael, Aristia, Felicidad, Lauren, Danielle, Allie, Jeffrey, Amanda, Tommy, Marcel, C Leigh, Karma, Shelby, Christopher, Alvin, Arek, Chellie, Dani, Paul, Dani, Tara, Elly, Colleen, Natalie, Nathan, Ario, Laura, Cari, Margaret, Mary, Connor, Nathan, Jan, Jerome, Brian, Azomonas, Ellie, University Greens, Joseph, Melody, Patricia, Matthew, Garrett, John, Ashley, Cathrine, Melvin, OrangeJulian, Porter, Jules, Griff, Joan, Megan, Marabeth, Les, Ali, Southside Plants, Keiko, Robert, Bryce, Wilma, Amanda, Helen, Mikey, Michelle, German, Joerg, Cathy, Tate, Steve, Kae, Carole, Mr. Keith Santner, Lynn, Aaron, Sara, Kenned, Brett, Jocelyn, Ethan, Sheryl, Runaway Goldfish, Ryan, Chris, Alana, Rachel, Joanna, Lori, Paul, Griff, Matthew, Bobby, Vaibhav, Steven, Joseph, Brandon, Liam, Hall, Jared, Brandon, Christina, Carly, Kazys, Stephen, Katherine, Manny, doeg, Daniel, Tim, Philip, Tim, Lisa, Brodie, Bendix, Irene, holly, Sara, and Margie. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Can humanity ever know everything? Explore the hard limits of knowledge: cosmic horizons, quantum measurement, chaos, computation, lost meaning, AI, wisdom, and the shoreline of the unknown.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurWatch my exclusive video Colonizing Ocean Worlds: https://nebula.tv/videos/isaacarthur-colonizing-ocean-worlds-subaquatic-settlementsCheck out Gods & Monsters: https://nebula.tv/curiousarchive/gods-and-monsters?ref=isaacarthur
Can humanity ever know everything? Explore the hard limits of knowledge: cosmic horizons, quantum measurement, chaos, computation, lost meaning, AI, wisdom, and the shoreline of the unknown.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurWatch my exclusive video Colonizing Ocean Worlds: https://nebula.tv/videos/isaacarthur-colonizing-ocean-worlds-subaquatic-settlementsCheck out Gods & Monsters: https://nebula.tv/curiousarchive/gods-and-monsters?ref=isaacarthur
In this episode the guys break down five weird and common things people do that cause or worsen chronic pain — poor sleep, inflammatory diet, macro and micro deficiencies, dehydration, and shallow breathing. They cover the difference between acute pain and chronic pain, how movement pattern issues are almost always the root cause, and why the experience of pain can be just as real as the physiological signal. They also get into Arthur Saxon pressing 370 pounds overhead with one arm in 1905, eating 24 eggs and 10 pounds of meat a day, the genetics study showing hyper responders gain three times as much muscle as average responders, Sal going back to jiu jitsu and the whole family trying the Organifi parasite cleanse, Manukora honey on mat burns, and how poor sleep is the number one injury predictor — worse than skipping a warmup. Then they coach live callers submitted through mplivecaller.com. MAPS Upper Lower: https://mapsupperlower.comCode: LAUNCH for 40% off. Includes male and female programs, workout videos, exercise demos, coaching videos and live coaching with Cole. Mind Pump Fitness Coaching: https://mindpumpfitnesscoaching.com1.9 NASM CEUs SPONSORS Organifi (natural parasite cleanse): https://organifi.com/mindpumpCode: MINDPUMP for 20% off. Run two cycles 15 days apart. Discussed on air — Sal's whole family has started doing it. Manukora Manuka Honey: https://manukora.com/MINDPUMPCode: MINDPUMP for up to 31% off plus $25 in free gifts with the Starter Kit. Discussed on air for wound healing and anti-inflammatory properties. Eight Sleep (Pod 5 Ultra) : https://eightsleep.com/mindpumpCode: MINDPUMP for up to $350 off. HSA/FSA may qualify — qualified customers save about 30% on average through Truemed. Truemed is for qualified customers. HSA/FSA tax savings vary. LINKS Submit a live caller question: https://mplivecaller.com Mind Pump Store: https://mindpumpstore.com Maps Fitness Products: https://mapsfitnessproducts.com Instagram: @mindpumpmedia 0:00 - Intro 2:20 - 5 weird things you do that make chronic pain worse 5:45 - Acute pain vs. chronic pain and why movement pattern issues are almost always the root cause 12:32 - Weird cause #1: Poor sleep — why it's worse for injury risk than skipping your warmup 16:00 - Weird cause #2: Diet and inflammation — Sal's gluten reaction and how to test for food intolerances 19:31 - Weird cause #3: Macro and micro deficiencies — protein, fat, magnesium and vitamin D 22:53 - Weird cause #4: Water intake — why hydration directly changes pain perception 26:52 - Weird cause #5: Shallow breathing — how breathing patterns keep muscles chronically tight 34:12 - Arthur Saxon — 370lb one-arm press in 1905, 24 eggs for breakfast and 10 pounds of meat at dinner 43:01 - Genetics study: hyper responders gain three times more muscle than average in six months 47:17 - Sal back at jiu jitsu, Manukora honey on mat burns and the whole family on parasite cleanses 1:00:32 - Caller: Candy (California) — went from 34 to 28% body fat eating more, freaked out and cut calories, gets a coach 1:16:26 - Caller: Jessica (Massachusetts) — 9 months postpartum, eating disorder history, 1742 calories, redlining 1:32:36 - Caller: Ruth (New Jersey) — 55 years old, chronic dieting history, gut issues derailing reverse diet 1:45:14 - Caller: Angela (Washington) — trainer and business owner, 20% body fat, chasing goals and needs a new direction