Podcasts about genes

¿Estamos realmente solos en el universo? Los expertos analizan tradiciones egipcias, sumerias y más para descubrir si pudo haber encuentros reales con seres estelares.

In this special end-of-year episode of Behind the Genes, host Sharon Jones is joined by Dr Rich Scott, Chief Executive Officer of Genomics England, to reflect on the past year at Genomics England, and to look ahead to what the future holds.  Together, they revisit standout conversations from across the year, exploring how genomics is increasingly embedded in national health strategy, from the NHS 10-Year Health Plan to the government's ambitions for the UK life sciences sector. Rich reflects on the real-world impact of research, including thousands of diagnoses returned to the NHS, progress in cancer and rare condition research, and the growing momentum of the Generation Study, which is exploring whether whole genome sequencing could be offered routinely at birth.  This episode offers a thoughtful reflection on how partnership, innovation, and public trust are shaping the future of genomic healthcare in the UK and why the years ahead promise to be even more exciting.  Below are the links to the podcasts mentioned in this episode, in order of appearance:  How are families and hospitals bringing the Generation Study to life? How can cross-sector collaborations drive responsible use of AI for genomic innovation? How can we enable ethical and inclusive research to thrive? How can parental insights transform care for rare genetic conditions? How can we unlock the potential of large-scale health datasets? Can patient collaboration shape the future of therapies for rare conditions? https://www.genomicsengland.co.uk/podcasts/what-can-we-learn-from-the-generation-study “There is this view set out there where as many as half of all health interactions by 2035 could be informed by genomics or other similar advanced analytics, and we think that is a really ambitious challenge, but also a really exciting one.”  You can download the transcript, or read it below. Sharon: Hello, and welcome to Behind the Genes.   Rich: This is about improving health outcomes, but it's also part of a broader benefit to the country because the UK is recognised already as a great place from a genomics perspective. We think playing our role in that won't just bring the health benefits, it also will secure the country's position as the best place in the world to discover, prove, and where proven roll out benefit from genomic innovations and we think it's so exciting to be part of that team effort.  Sharon: I'm Sharon Jones, and today I'll be joined by Rich Scott, Chief Executive Officer at Genomics England for this end of year special. We'll be reflecting on some of the conversations from this year's episodes, and Rich will be sharing his insights and thoughts for the year ahead. If you enjoyed this episode, we'd love your support, so please subscribe, rate, and share on your favourite podcast app. So, let's get started.  Thanks for joining me today, Rich. How are you?  Rich: Great, it's really good to be here.   Sharon: It's been a really exciting year for Genomics England. Can you tell us a bit about what's going on?  Rich: Yeah, it's been a really busy year, and we'll dive into a few bits of the components we've been working on really hard. One really big theme for us is it's been really fantastic to see genomics at the heart of the government's thinking. As we'll hear later, genomics is at the centre of the new NHS 10-year health plan, and the government's life sciences sector plan is really ambitious in terms of thinking about how genomics could play a role in routine everyday support of healthcare for many people across the population in the future and it shows a real continued commitment to support the building of the right infrastructure, generating the right evidence to inform that, and to do that in dialogue with the public and patients, and it's great to see us as a key part of that.  It's also been a really great year as we've been getting on with the various programmes that we've got, so our continued support of the NHS and our work with researchers accessing the National Genomic Research Library. It's so wonderful to see the continued stream of diagnoses and actionable findings going back to the NHS. It's been a really exciting year in terms of research, publications. In cancer, some really exciting publications on, for example, breast cancer and clinical trials. Really good partnership work with some industry partners, really supporting their work. For me, one of the figures we are always really pleased to see go up with time is the number of diagnoses that we can return thanks to research that's ongoing in the research library, so now we've just passed 5,000 diagnostic discoveries having gone back to the NHS, it really helps explain for me how working both with clinical care and with research and linking them really comes to life and why it's so vital.   And then, with our programmes, it's been great to see the Generation Study making good progress. So, working with people across the country, more than 25,000 families now recruited to the study, and we're beginning to hear about their experiences, including some of the families who've received findings from the programme. It's really nice to see and hear from Freddie's family, who talked to the press a bit about the finding that they received. Freddie was at increased risk of a rare eye cancer, and really pleasingly, it was possible to detect that early through the screening that was put in place. Again, it really brings to life why we're doing this, to make a difference and improve health outcomes.  Sharon: That's an incredible 12 months. Diving into that Generation Study piece and for listeners who don't know what that is, it's a research study in partnership with the NHS that aims to sequence the genomes of 100,000 newborn babies. On an episode from earlier in the year, we had mum, Rachel Peck, join the conversation, whose baby Amber is enrolled on a study. Let's year from Rachel now.  Rachel: From the parents' point of view, I guess that's the hardest thing to consent for in terms of you having to make a decision on behalf of your unborn child. But I think why we thought that was worthwhile was that could potentially benefit Amber personally herself or if not, there's the potential it could benefit other children.  Sharon: Consent has been such a big area of focus for us, Rich, and Rachel touches on that complexity, you know, making a decision on behalf of her unborn child. Can you talk a bit about our approach to consent in the Generation Study and what's evolving in that model?  Rich: Yeah. It's been for the whole study, really, starting out asking a really big question here, what we're aiming to do is generate evidence on whether and if so, how whole genome sequencing should be offered routinely at birth, and that's responding to a really ill need that we know that each year thousands of babies are born in the UK with treatable rare conditions. We will also need to see if whole genome sequencing can make a difference for those families, but we realise to do that, as with all screening, that involves testing more people than are going to benefit from it directly themselves. So, you have to approach it really sensitively. There's lots of complicated questions, lots of nuance in the study overall. One of them is thinking really carefully about that consent process so that families can understand the choices, they can understand the benefits and risks. This is still a research study. We're looking to understand whether we should offer this routinely. It's not part of routine care at this point. The evidence will help decision-makers, policymakers in the future decide that.  At the beginning of the programme, we spent a lot of time talking to families, talking to health professionals who understand the sorts of decisions that people are making at that time of life, but also are experts in helping think about how you balance that communication. That involved, as I say, a lot of conversations. We learnt a lot, lots of it practical stuff, about the stage of pregnancy that people are at when we first talk to them about the study, so that people aren't hurried and make this decision. What we've learnt in the study, right from the outset, is talking to people from midway through the pregnancy so that they really have time to engage in it and think about their choice. So, it's an important part of getting the study design right so that we run the study right. It's also a really crucial element of the evidence that will generate from the study so that we can understand if this is something that's adopted, how should we communicate about it to families. What would they want to know? What's the right level of information and how do we make that accessible in a way that is meaningful to people from different backgrounds, with different levels of interest, different accessibility in terms of digital and reading and so on. There's a lot that we've learnt along the way and there's a lot that we're still learning. And as I say, important things that we'll present as evidence later on.  Sharon: Thank you. It's fascinating there are so many moving parts and a lot to consider when you're building the design of a programme like this or study like this.  Earlier in the year you had a great conversation with Karim Beguir about the developments of AI in genomics. Let's revisit that moment.  Karim: We live in an extraordinary time. I want to emphasise the potential of scientific discovery in the next two or three years. AI is going to move, let's say, digital style technologies like coding and math towards more like science and biology. In particular, genomics is going to be a fascinating area in terms of potential.  Sharon: So, Karim talks about AI moving from maths and coding into biology. Why is genomics such a natural area for AI?  Rich: It's really fascinating. I think it links a lot to how we think about genomics and how you get the most value in terms of health benefit and sort of the progress that we can see could come through genomics more generally. So, your genome, which is your DNA code, written in 3 billion little letters across each one of us, one copied from mum, one copied from dad, even just our genomic code of one person is a large amount of data. That is just part of the story because we're not just interested in DNA for DNA's sake, this is about thinking about health and how we can improve health outcomes. So, it's also thinking about the other sorts of information that needs to link to genomic data to make a difference. Whether that's just to provide routine healthcare with today's knowledge, or whether it's about continuing to learn and discover.  As I mentioned at the beginning, I think a really important part of this whole picture is we've learnt a lot in the last 20/30/40 plus years about genomics. It's incredible how much progress has been made, and we're really just scratching the surface. Take rare disease and the progress that's been made there, it's wonderful how many more families we're able to help today. We know that many thousands of families we still can't find a diagnosis for when we know that there is one there for many of them. That theme of ongoing learning is at the centre of all of our work, and that will continue as we look about broader uses of genomics in other settings beyond rare conditions and cancer. It's also that ongoing learning, but also the amount of, at the moment, manual steps that are required in some of the processes that we need to, for example, find a diagnosis for someone or to make sure the tools that we use are the most up to date, the most up to date with the medical literature, for example. AI is a tool that we're, as the whole of the society, we're beginning to see how it can play a role. We see it as important today for some of the just really practical things. I mentioned it, staying up to date with the medical literature, making sure that we and our systems are aware of all of the knowledge that's coming in from around the world. It's got real potential there.  I think the biggest bottom line here is that it's got the potential to be a really important tool in terms of our ongoing learning and improvement. I'm a doctor by background, the human intelligence alone is fantastic, it's moved us a long way, but we know it also has tremendous blind spots. AI has the potential to complement us there. I guess another thing to really call out here, AI isn't a panacea, it's not suddenly going to answer all of the questions. And, just like human intelligence, it will have its own biases, have its own strong points, and less strong points.  One of the things we're really committed to is working with people like Karim, and many others, to understand where AI could make a difference, to test it, to generate evidence on how well it works and an understanding in all sorts of ways about how that might play out. And, make sure that as AI becomes a tool, that we in genomics, but also in other areas, we understand its strong points and where we need to be more careful and cautious with it. That's a really important part of what we're going to be doing in the coming years here, is making sure that we can maximise the impact of it, but also be confident, so that we can explain to people whose data we might use it on how we're doing it and what it's bringing.  Sharon: Thanks Rich. It's definitely a fast-moving conversation of which we really want to be part of. One of the things that's come up again and again this year is participation and co-production. Let's hear quote that really captures that.  Bobbie: In an earlier conversation with Paul, which you might find surprising that it's stuck with me so much, he used the word ‘extractive'. He said that he'd been involved in research before and looking back on it, he had felt at times it could be a little bit extractive. You come in, you ask questions, you take the data away and analyse it, and it might only be by chance that the participants ever know what became of things next. One of the real principles of this project was always going to be co-production and true collaboration with our participants.  Sharon: That was Professor Bobbie Farsides talking about moving away from extractive research towards true co-production. How are we making that shift in practice here at Genomics England?  Rich: It's a great question. It's one of the areas where I think we've learnt most as an organisation over the years about how really engaging from the beginning with potential participants in programmes, participants who join our programmes, people who are involved in delivering our programmes and healthcare is so important at the beginning. I mentioned earlier the work to think about the consent process for the Generation Study, and that's one of the areas where I think from our first programme, 100,000 Genomes Project, we learnt a lot about how to do that well, some of the pitfalls, some of the bits that are most challenging. And really, right from the start of our programmes, making sure that people who will potentially benefit from the programmes, potentially join them, can be part of that engagement process, and really part of the design and the shaping of the research questions, the parameters around research, but also the materials and how people will engage with them. And that's one of the key capabilities we have internally as an organisation, so we work with partners externally, but also it's a really key part of the team that we have at Genomics England.  Sharon: So, whilst Bobbie talked about moving away from research that can feel one-sided and towards true collaboration, in another episode, Lindsay, a parent of a child with a rare condition, reflected on what that change really means for families and how it's empowering to see their voices and experiences shaping future treatments.  Lindsay: Historically, there's been a significant absence of a patient voice in rare disease research and development. And knowing that that's changing, I think that's really empowering for families. To know that professionals and industry are actually listening to our stories and our needs and really trying to understand, that offers much greater impact on the care and treatments of patients in the future.  Sharon: So, what role do you see participants as partners in shaping the next phase of Genomics England's work?  Rich: So, as you probably detected from my last answer, we see it as absolutely vital. One of the really exciting things here at Genomics England, we've had a participant panel from very early in our life as an organisation. That's one really important route to us at the heart of our organisation, part of our governance, making sure that participants representing all sorts of parts of our programme, but rare conditions being a really large focus for us. And I think, what's so striking as someone with a medical and a research background can see how I think historically medics and researchers have sometimes not known, sort of maybe been a bit scared about knowing how to involve participants from the outset. Often, because they're worried that they might ask the wrong questions in the wrong way, they just don't have the tools.   One of the things I often say now to people we work with is one of the most empowering and positive experiences we have at Genomics England is the power of our participants helping to, right from the beginning, shape what the questions are that we should be asking. Realise some of the challenges that you can't possibly, if you're not in their shoes, understand are the most important to really shape how we prioritise our work internally, the problems that we need to solve first, how we think about some of the practical impacts on people's lives that, again, without hearing from their voice you just wouldn't know. And again, to help our researchers, people accessing data in the National Genomic Research Library, helping them make sure that they involve participants in their work and the confidence and tools to do that.  Sharon: That's great, thank you. Another big theme this year has been collaboration across the NHS, academia, and industry. Dr Raghib Ali puts this really well.  Raghib: There are areas where academia and the NHS are very strong, and there are areas where industry is very strong, and why working together, as we saw, you know, very good examples during the pandemic with the vaccine and diagnostic tests, etc., a collaboration between the NHS, academia, and industry leads to much more rapid and wider benefits for our patients and, hopefully, in the future for the population as a whole in terms of early detection and prevention of disease.  Sharon: So, how does collaboration fit into the 10-year health plan and what's next for 2026 in that space, Rich?  Rich: I think one of the most enjoyable parts of my role at Genomics England and our role as an organisation is the fact that we see ourselves very much as part of a, sort of team across the UK and in fact internationally in terms of delivering on the potential we see for genomics. So, we have a vision as an organisation, which has been the same the last 5 or so years, which is a world where everyone can benefit from genomic healthcare. In fact, that vision is now shared by the NHS from a genomics perspective, and really demonstrably, the 2 parts of the system absolutely pointing in the same direction. And when we've been thinking, looking forward with that 10-year lens on it, what we always like to do, and I think it's a real privilege to be able to do, because we're here in the UK, because we have a National Health Service, because there's been that long-term commitment from government on genomics and really taking a long-term investment view there, and because of so many other parts of the ecosystem, other experts who access data in the National Genomic Research Library, research organisations like Our Future Health, UK Biobank, all teaming together, and the expertise that's there in genomics more broadly. So we've, if you like, worked back from what the UK could do as whole, and in the 10-year health plan, as I said earlier, genomics is at the heart of that.  There's a double helix on the front cover and, in fact, on the watermark on almost every page. And, there's this view set out there where as many as half of all health interactions by 2035 could be informed by genomics or other similar advanced analytics. And we think that that's a really ambitious challenge. We see a really important role for us, as Genomics England, in contributing to that, but it's very much a team effort. Our role is around where we have the biggest capabilities, so around building and running digital infrastructure at a national scale for healthcare delivery and for research, to building evidence to inform future policies, so running programmes like the Generation Study to inform future policy. And really, as part of that, that evidence piece, being driven by engagement, ethics, and work on equity, to really make sure that evidence that future policy can be built on is informed by a fully rounded view. We think if we do that right that we could as a country with others, the NHS, research organisations, many others could live up to that ambition that's set out there in the 10-year plan.   And the 10-year plan is really clear, and government is really clear that this is about improving health outcomes. But it's also part of a broader benefit to the country because the UK is recognised already as a great place from a genomics perspective. We think playing our role in that won't just bring the health benefits, it also will secure the country's position as the best place in the world to discover, prove and where proven role out benefit from genomic innovations. And we think it's so exciting to be part of that team effort.  Sharon: So, Genomics England's refreshed mission and direction of travel is really setting out how we move from research to routine care, and how we embed genomics across the health system. Carlo Rinaldi captured the idea perfectly, imagining a future where diagnosis and hope arrive hand in hand.  Carlo: My dream is that in five to ten years' time an individual with a rare disease is identified in the clinic, perhaps even before symptoms have manifested. At that exact time the day of the diagnosis becomes also a day of hope, in a way, where immediately the researcher, the genetic labs, flags that specific variant, that specific mutation. We know exactly which is the best genetic therapy to go after.   Sharon: And Rich, what are your thoughts on that?  Rich: I think Carlo captures it really well. And for us, I think a really big theme is for that potential for genomics to make a difference, a continued and in fact increased difference for people with rare conditions and cancer, areas where it's already making a difference, but also with the potential to make a much broader impact for people across the population. The real theme is embedding genomics into routine care, making it something that you don't need to know that you're seeing an expert in genomics to benefit from it, really make sure that those benefits can be felt as just part of routine care. It's not something separate where we recognise that the best healthcare is healthcare that's supported by all sorts of inputs, with genomics being a key part of that, and that we can continue to learn as we do that. So that with people's consent, with their understanding of how their data is being used, we know that if we don't have the best answer for them today, we give the best answer we can today, and we can continue to learn, and they can benefit from that in the future.   I'm a rare disease doctor by background, and one of the really most enjoyable parts of my job is seeing that come to practice. In the last year or so I've had a number of families where I've been seeing the family for years, and a researcher accessing data in the National Genomic Research library has found an answer that we've not been able to find for maybe their child's whole life, and then finally we're able to feed it back. Seeing that come to life is just so wonderful, and I think gives us a bit of a blueprint for how things could work more generally.  Sharon: That's great. I mean, what a feeling for those families who do get those answers. As we look ahead to 2026 and beyond, the conversation is starting to include prevention, using genomics not just to diagnose conditions but to predict and treat and even prevent them. Alice Tuff-Lacey summarised this nicely in an episode about Generation Study.  Alice: This is quite an exciting shift in how we use whole genome sequencing, because what we're talking about is using it in a much more preventative way. Traditionally where we've been using it is diagnostically where we know someone's sick and they've got symptoms of rare condition, and we're looking to see what they might have. What we're actually talking about is screening babies from birth using their genome to see if they're at risk of a particular condition. And what this means is this raises quite a lot of complex ethical, operational, and scientific and clinical questions.  Sharon: Rich, when you think about 2026, what's your biggest hope for where we'll be this time next year?  Rich: I think it's a really exciting time. As you can tell from how we've been speaking, I'm really excited about the direction of travel and how over the next 5 and 10 years we can really make a transformational shift because of how well placed we are in the UK from a genomics perspective. Where we are with today's knowledge, where we could be because of the continued government and NHS commitment to genomics being at the heart of this, if we build the right infrastructure, if we generate the right evidence to inform what's adopted, I think we're in a really exciting place.  From a 2026 perspective, I think what we're really committed to is continuing to do the work, the day-by-day-by-day work that is to build that incrementally. So, a really big focus for us is continuing to support the NHS and making sure researchers can access data, so that flow of answers for families can continue and grow, accelerate, to continue delivering the Generation Study because it's a really important part of that wider jigsaw to generate the evidence that can inform future policy on whether this is something that's adopted and offered routinely to every child when they're born.  I think a really important time now that the government's provided the opportunity for us as a team, as a UK genomics and life sciences ecosystem, is to really put in place some of the next steps, the building blocks that can take us towards that 10-year vision. So for us also, a really important part of the year is beginning the design process for an adult population genomics programme, where we're looking at what evidence it's important that we can provide that's complementary to different work around by others in the ecosystem that needs to be there if we're going to think about that potential broader use of genomics.  Sharon: That's great. It sounds like another exciting year ahead. So, we're going to wrap up there. Thank you to Rich Scott for sharing your reflections on the key milestones this year, and for your thoughts on the year ahead. Thanks, Rich.  Rich: Thanks very much for having me.  Sharon: If you enjoyed today's episode, we'd love your support, so please subscribe, share, and rate us on wherever you listen to your podcasts. I've been your host, Sharon Jones. This podcast was produced by Deanna Barac and edited by Bill Griffin at Ventoux Digital. Thank you for listening. 

Desde espectaculares exhibiciones de fuegos artificiales hasta refrescantes baños en el mar, las naciones celebran el comienzo de 2026.

Cerramos 2025 contando el trabajo de Trib-Arte, donde la ayuda social y cultural son un bien que debemos seguir aplicando, por otro lado Maruja Salgado nos invita a la firma de libros desde la Cueva Pintada el sábado 3 de enero desde las 12h del mediodía, conoce la historia de "Abenchara, la Guayarmina olvidada". Hablamos de años nuevos, de últimas noticias y como cada semana nos vamos a escena con Zálatta Espacio Escénico y los proyectos del próximo año. Todo en La Diez Capital Radio y Capital Radio Gran Canaria con Joam Walo "poniendo lo canario más de moda que nunca y apostando por lo nuestro" #origenes #programaorigenes #ladiezradio #capitalradiogc #joamwalo

El Año Nuevo ha estado marcado, en distintas culturas y épocas, por costumbres y rituales cargados de simbolismo. En este episodio de Interesante Historia exploramos el origen y significado de prácticas que buscan atraer la buena suerte, dejar atrás lo viejo y dar la bienvenida a nuevos comienzos, desde tradiciones ancestrales hasta hábitos que siguen vigentes hoy.En este final de temporada, haremos un recorrido breve y revelador por las creencias, gestos y ceremonias que acompañan una de las transiciones más importantes del calendario y que reflejan cómo las sociedades han intentado influir en el destino al iniciar un nuevo ciclo.¡Muchas gracias por acompañarme este 2025 y que el año que comienza sea el mejor para ustedes y sus seres queridos!

Peritos arribaron a la zona del choque en la calzada San Antonio Abad, en la #CDMX, y en redes sociales comenzó a circular un video del presunto conductor momentos antes en otra zona de la capital.See omnystudio.com/listener for privacy information.

Los escritores Javier Lorenzo, Eloy Cebrián y Arturo Tendero hablan de fotografía, de periodismo y de actualidad con el fotógrafo del periódico albaceteño, José Miguel Esparcia, y el director del medio, Javier Martínez

Programa ESPECIAL de NAVIDAD de “Voces del Misterio”, en el que hablamos de los orígenes, de los mitos y las tradiciones de la Navidad y de estas fechas que conmemoran el nacimiento de Jesús de Nazaret. Igualmente de lo que nos dice la tradición solar, astronómica y astrológica. RECORDAROS que este PODCAST NO es el OFICIAL del programa “Voces del Misterio”. Para comentarios sobre los temas tratados o las opiniones de los colaboradores, podeís contactar directamente con el programa a través de su web (https://www.vocesdelmisterio.com) o el correo electrónico: "vocesdelmisterio@gmail.com". Podeís seguirnos a través de la WEB (https://paranormaliaweb.github.io/), FACEBOOK (https://www.facebook.com/paranormaliaweb/) o X (https://x.com/paranormaliaweb). ¡FELICES FIESTAS!

Hoy día de Nochebuena, en vivo tuvimos a oyentes, amigos y personalidades que nos visitaron en la sede de La Diez Capital Radio y con quienes compartimos. Don Santos, Miguel y Antonio nos contaron como viven estos días, por otro lado Pepe Rodríguez de Capital Radio Gran Canaria nos comenta como se está preparando la Navidad en Gran Canaria; además desde Don Bernardo Iglesias, Presidente del Centro Cultural y de Recreo de Arafo, nos habla de los Premios Añavingo de este 2025 que recae en el Grupo Folclórico Tigaray. Y hablando con Antonio Díaz de la Asociación Cultural Tajaraste y su próximo espectáculo "Vivencias" recibimos en el estudio al Consejero de Cultura del Cabildo de Tenerife, Don José Carlos Acha, sirvió para saber como afrontar el 2026 en cuanto a Folclore se refiere. Victor López del Grupo Folclórico Los Tagorosteros nos invitan a su Encuentro de Villancicos el domingo 28 de diciembre en Tacoronte y como cada semana nos vamos a escena con Zálatta Espacio Escénico y así recibimos la Navidad en Orígenes... "poniendo lo canario más de moda que nunca y apostando por lo nuestro" #origenes #programaorigenes #ladiezradio #capitalradiogc #joamwalo

En este fascinante episodio, el profesor Alberto del Campo Tejedor nos lleva a un viaje a través de la historia de la Navidad, desde sus raíces paganas hasta su celebración actual en Colombia y América Latina. Descubrimos cómo las antiguas festividades grecorromanas, como las Saturnalias, influyeron en la forma en que celebramos hoy. Tejedor explica la transición del culto al dios sol invicto hacia la celebración del nacimiento de Jesucristo, y cómo tradiciones como las novenas y el uso de ropa interior amarilla han evolucionado. Además, se discute el impacto del consumismo en la festividad moderna y la importancia de los rituales mágicos que perduran en nuestra cultura. Un análisis profundo que revela la amalgama de tradiciones que conforman la Navidad contemporánea.

"Voces del Misterio" EXPRESS en el que hablamos de los orígenes, de los mitos y las tradiciones de la Navidad y de estas fechas que conmemoran el nacimiento de Jesús de Nazaret. Igualmente de lo que nos dice la tradición solar, astronómica y astrológica. Un tema apasionante que, sin dudas, te gustará. En "Voces del Misterio", ¡no te lo pierdas! Voces del Misterio EXPRESS: Orígenes, mitos y tradiciones de la Navidad. Programa ESPECIAL DE NAVIDAD.

Tecnología extraordinaria La impresionante ingeniería de los yacimientos megalíticos antiguos, sugiere el uso de tecnología avanzada. Los expertos exploran sitios como Guiza y Puma Punku en busca de pruebas. Encuentros en la tercera fase Culturas antiguas describen máquinas voladoras como el pájaro de Saqqara o las vimanas. Los expertos analizan textos y objetos para probar encuentros con extraterrestres.

Welcome back to Episode #197 of the PricePlow Podcast, where we take you inside Helaina’s Manhattan research and development facility for an in-depth conversation with CEO Laura Katz and Pamela Besada-Lombana (Pam), Director of Early R&D. After our initial online episode with Laura back in June, we traveled to New York to experience firsthand the groundbreaking precision fermentation work happening in the heart of Midtown Manhattan. This episode reveals the sophisticated science, collaborative culture, and clinical validation driving effera® lactoferrin from a novel ingredient to an industry-changing reality. In this conversation, Pam takes us deep into the yeast engineering process that makes effera possible, explaining how her team designs, builds, and optimizes microbial factories to produce human-equivalent lactoferrin more efficiently with each iteration. Laura shares recent clinical breakthroughs, including the landmark alloimmunization study that proved effera triggers no immune response while bovine lactoferrin does, along with emerging data on gut permeability and microbiome health. The discussion also explores Helaina’s empathy-driven culture, their data infrastructure capturing 170 million rows of metabolic information, and how they’re attracting innovative brands that value genuine science and transparency. This episode complements our earlier conversation with Helaina’s Dan DeMarino and Anthony Clark from the same New York trip. Subscribe to the PricePlow Podcast on your favorite platform and sign up for Helaina news alerts before diving in. https://blog.priceplow.com/podcast/helaina-laura-katz-pamela-lombana-197 Video: Inside Helaina’s Manhattan Lab with Laura Katz and Pam Besada-Lombana https://www.youtube.com/watch?v=4LWUrgTkF98 Detailed Show Notes: The Science and Strategy Behind effera® Lactoferrin (0:00) – Welcome to Helaina’s Manhattan Research Facility (2:00) – Pam’s Background in Yeast Engineering (3:30) – The Product Stays the Same, Production Gets Better (5:30) – Reprogramming Yeast: Fighting 5,000 Genes (8:00) – Understanding Non-Conventional Yeast Metabolism (14:30) – Scaling the Innovation: 300 Edits Every Five Weeks (18:00) – Capturing 170 Million Rows of Data (19:00) – The Design-Build-Assess-Learn Cycle (23:00) – From Small-Scale Screening to Commercial Production (28:00) – A Decade of Precision Fermentation Expertise (32:00) – Pam’s Journey to Helaina (36:40) – Recent Clinical Data and Product Launches (37:40) – Empathy as a Core Value (40:00) – The Story Behind Helaina’s Wall of Women (41:00) – The Landmark Alloimmunization Study (44:00) – The Friday Evening Result (45:00) – Taking the Risk on Comparative Clinical Research (46:00) – Lab Space Constraints and Mindful Growth (47:45) – Building the Data Science Team (50:10) – AI-Assisted Hypothesis Generation (50:50) – The Data Behind the Platform (51:50) – Explaining Lactoferrin to a Friend (53:00) – The Ethics of Bovine Colostrum (54:00) – Closing:… Read more on the PricePlow Blog

Send us a textIn this episode, we discuss an approach to familial hypercholesterolemia, with a focus on different screening, diagnostic, and treatment thresholds based on one's individual risk. Written by: Dr. Nour Marafie. Reviewed by: Dr. Morris Schweitzer  and Dr. Matthew Ades.Support the show

Today we sit with the old questions and let them breathe again, tracing the places where life begins to feel like a presence rather than a computer. Turner walks through the fault lines of modern biology, pointing to the quiet mind-like shimmer in organisms shaping their worlds. The conversation moves slowly, deliberately, as if the universe itself were leaning in to listen. By the end, the idea of agency feels less like a taboo and more like something we've sensed all along.Part 1: https://youtu.be/MOr-FZ_ogTIPATREON https://www.patreon.com/c/demystifysciPARADIGM DRIFThttps://demystifysci.com/paradigm-drift-showHOMEBREW MUSIC - Check out our new album!Hard Copies (Vinyl): FREE SHIPPING https://demystifysci-shop.fourthwall.com/products/vinyl-lp-secretary-of-nature-everything-is-so-good-hereStreaming:https://secretaryofnature.bandcamp.com/album/everything-is-so-good-here00:00 Go! 00:08:43 – Gene-Centered Evolution Takes Over00:11:10 – McClintock's Discovery Breaks the Mold00:14:19 – Genes as Interpreted Signals, Not Dictators00:18:11 – From Mutationism to Epigenetics00:20:41 – Dawkins and the Selfish Gene Frame00:24:30 – Life Strives for More Than Survival00:27:47 – Culture as a Force in Evolution00:30:28 – Termites and Environmental Inheritance00:32:22 – When Literalism Distorts Science and Religion00:35:22 – Beyond Gould's Magisteria00:39:02 – The Aiming of Organisms00:41:58 – Desire, Agency, and Evolutionary Trajectories00:44:14 – Human Exceptionalism and the Myth of Evolution's End00:47:46 – Cultural Barriers to Integrative Biology00:49:39 – The Transcendence of Materials00:52:10 – Purposeful Behavior in Termite Societies00:55:35 – Preference and Purpose in Termite Architecture00:59:14 – Human Metaphysics and Cognitive Niches01:04:19 – Cracks in the Evolutionary Consensus01:06:39 – Biology as the Bridge Between Facts and Meaning01:08:58 – The Missing Definition of Life01:10:59 – Biology's Identity Crisis01:12:36 – Rethinking Life and the Universe01:15:08 – The Origin of Life Problem01:16:28 – From Chemistry to Cognitive Emergence01:20:27 – Life as a Gradual Flame01:23:13 – Agency as the Heart of Biology01:25:42 – The Scientific Struggle With Agency01:27:04 – Turner's Work on Organisms, Design, and Purpose #consciousness, #agency , #evolution, #originoflife, #emergence, #complexity , #cognition , #purpose , #epigenetics , #philosophy, #meaning, #physicspodcast, #philosophypodcast MERCH: Rock some DemystifySci gear : https://demystifysci-shop.fourthwall.com/AMAZON: Do your shopping through this link: https://amzn.to/3YyoT98DONATE: https://bit.ly/3wkPqaDSUBSTACK: https://substack.com/@UCqV4_7i9h1_V7hY48eZZSLw@demystifysci RSS: https://anchor.fm/s/2be66934/podcast/rssMAILING LIST: https://bit.ly/3v3kz2S SOCIAL: - Discord: https://discord.gg/MJzKT8CQub- Facebook: https://www.facebook.com/groups/DemystifySci- Instagram: https://www.instagram.com/DemystifySci/- Twitter: https://twitter.com/DemystifySciMUSIC: -Shilo Delay: https://g.co/kgs/oty671

In the last episode of the podcast, Stephen Dubner turns the microphone on Steve Levitt. They talk about Levitt's favorite — and least favorite — moments from the show's five-year run, his quest to reform education, and his next podcasting gig. SOURCES:Stephen Dubner, host of Freakonomics Radio, co-author of Freakonomics books. RESOURCES:"How to Help Kids Succeed," by People I (Mostly) Admire (2025)."Feeling Sound and Hearing Color," by People I (Mostly) Admire (2024)."Richard Dawkins on God, Genes, and Murderous Baby Cuckoos," by People I (Mostly) Admire (2024)."Arnold Schwarzenegger Has Some Advice for You," by People I (Mostly) Admire (2024)."Werner Herzog Thinks His Films Are a Distraction," by People I (Mostly) Admire (2023)."Drawing from Life (and Death)," by People I (Mostly) Admire (2023)."Yuval Noah Harari Thinks Life is Meaningless and Amazing," by People I (Mostly) Admire (2022)."Is This the Future of High School?," by People I (Mostly) Admire (2022)."Does Death Have to Be a Death Sentence?," by People I (Mostly) Admire (2022)."Sal Khan: 'If It Works for 15 Cousins, It Could Work for a Billion People.'" by People I (Mostly) Admire (2021)."Jared Diamond on the Downfall of Civilizations — and His Optimism for Ours," by People I (Mostly) Admire (2021)."Amanda & Lily Levitt Share What It's Like to be Steve's Daughters," by People I (Mostly) Admire (2021)."How Rahm Emanuel Would Run the World," by Freakonomics Radio (2020).The Levitt Lab. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

En un nuevo capítulo de Réplica, Daniel Mansuy conversó con Juan Francisco Lecaros sobre su libro “En busca de los comienzos de Chile”. Un texto en el que el autor recorre los paisajes que forjaron el país y revive las historias que nacieron al alero de esos senderos.

We are currently living in an epidemic of a sedentary lifestyle. As we live through our screens whether it be glued to our phones, tablets, or laptops, we tend to miss out on the benefits of movement in our day to day lives - how does movement benefit us?In this episode, Dr. Krista Kostroman, Chief Science Officer of the DNA Company, is joined by Dr. Emily Splichal. She is a functional podiatrist and human movement specialist, is the mind behind Naboso. With a spirit to challenge conformity, Dr. Splichal has taken her conventional Podiatric Medical degree and combined it with years of experience and expertise in human movement and sensory science to found Naboso.Dr. Splichal believes that our experience in this world is built around sensory stimulation and our ability to process, perceive, and integrate this information effectively. Since 2012, Dr. Splichal has been traveling the world to share her unique approach to human movement, foot function, and barefoot science. Having taught in 35 countries and to over 25,000 professionals, Dr. Splichal has quickly become a sought out leader in barefoot training and rehabilitation. Here are the highlights of today's episode:03:59 How Our Body Feeds Into Mental Experiences08:59 How People Can Shift Through Movement and Fascial Engagement15:17 Walking as An Access Point to Health26:04 How Fascia and Movement Informs Our Genetic Expression40:16 Supporting Fascia and Microvasculature46:33 Reintegrating Body with Space51:43 ConclusionIf you wish to learn more from Dr. Emily Splichal and Naboso, you may do so through the following channels:Website: https://www.naboso.com/Instagram: https://www.instagram.com/naboso_technology/YouTube: Master Movement with Naboso______________________________________________________Keep yourself up to date on The DNA Talks Podcast! Follow our socials below:The DNA Talks Podcast Instagram: @dnatalkspodcastThe DNA Company Instagram: @thednacoThe DNA Company's Official Tiktok Account: @thednaco3______________________________________________________Medical Disclaimer: The information provided in this communication is for general informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read here. If you think you may have a medical emergency, call your doctor or 911 immediately.

Orígenes milenarios de la meditación S9 E290Descubre los secretos milenarios de la meditación y cómo esta práctica ancestral puede transformar tu mente, tu energía y tu vida diaria.

Support the show¿QUIÉNES SON LOS IMPARABLES?Imagina iniciar cada día rodeado de empresarios que, como tú, están decididos a crecer, mejorar y transformar sus resultados.

Vote for Jimmy's Jobs People's Choice Award: https://politicalpodcastawards.co.uk/the-peoples-choice-award/ And sign up to our NEW community here! https://app.heartbeat.chat/jimmysjobsbackstage/invitation?code=DF4BEJ Insights into High-Stakes Marketing: A Conversation with Uncensored CMO Join us for an in-depth conversation with Jon, the host of Uncensored CMO, as we explore the nuances of marketing in today's fast-paced world. In this engaging episode, Jon delves into his unique career journey from finance to marketing, the strategic decisions surrounding bold marketing campaigns like Jaguar's rebrand and Sydney Sweeney's campaign for American Eagle, and the distinction between distinctive and different marketing. Additionally, we discuss the challenges and strategies for running a successful podcast, the future of marketing, and the importance of networking and understanding consumer behavior. This episode is packed with valuable insights for anyone interested in the evolving world of marketing and podcasting. ********** Follow us on socials! Instagram: https://www.instagram.com/jimmysjobs Tiktok: https://www.tiktok.com/@jimmysjobsofthefuture Twitter / X: https://www.twitter.com/JimmyM Linkedin: https://www.linkedin.com/in/jimmy-mcloughlin-obe/ Want to come on the show? hello@jobsofthefuture.co Sponsor the show or Partner with us: sunny@jobsofthefuture.co Credits: Host / Exec Producer: Jimmy McLoughlin OBE Producer: Sunny Winter https://www.linkedin.com/in/sunnywinter/ Junior Producer: Thuy Learn more about your ad choices. Visit podcastchoices.com/adchoices

Hablamos de epigenética y cómo podemos "entrenar" nuestros genes a través de buenos hábitos de alimentación y salud. Lo hacemos de lamano del doctor Alexandre Olmos. Presentado por Yolanda Vázquez Mazariego. 

Dr. Martin Picard, PhD, is a professor of behavioral medicine at Columbia University and an expert on how our behaviors and psychology shape cellular energy production and rates of aging. He explains that your mitochondria don't just “make energy”; they translate what you do—your mindset and your relationships—into the energy you experience as vitality or lack thereof. He explains how exercise, nutrition, sleep, meditation, and even certain thought patterns and our sense of purpose can charge our cells like batteries. He also shares findings that hair greying is the result of cellular stress and is reversible. This episode links physical and mental ‘energy' with cellular energy and provides science-supported tools to improve your physical and mental health. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Helix: https://helixsleep.com/huberman Lingo: https://hellolingo.com/huberman Function: https://functionhealth.com/huberman Waking Up: https://wakingup.com/huberman Timestamps (00:00:00) Martin Picard (00:03:50) What is Energy?, Energy Flow & Transformation (00:07:53) Energy, Vitality, Emotions, Sensory Perception (00:14:18) Sponsors: Helix Sleep & Lingo (00:17:19) “Mito-Centric” View of World, Mitochondrial Energy & Information Patterns (00:25:26) Organelles, Mitochondria & Energy Transformation; Maternal Genes (00:31:12) Mitotypes & Differentiation, Mitochondria as “Social Organisms” (00:36:52) Food & Dysfunctional Energy Transformation (00:40:02) Lifestyle Choices & Interests, Physiological Growth (00:46:39) Pregnancy, Amenorrhea; Illness & Tiredness (00:51:07) Sponsor: AG1 (00:52:29) Energy Transformation & Distribution; Body's Wisdom, Feeling Sick (00:56:27) Tool: Feel Your Energy; Breath & Energy (01:02:31) Flow of Energy; Trade-Offs, Life Purpose & Enjoyment (01:10:15) Biology, Meaningful Experiences & Energy Flow (01:16:27) Sponsor: Function (00:18:15) Inflammation, Energetic Flow (01:20:43) Child Prodigies, Species Lifespan & Mitochondrial Metabolism; Aging (01:28:56) Lifestyle & Aging: Exercise, Fasting; Inflammation, Sleep, Stimulants (01:37:06) Energetic Stress Signals, GDF-15, Cancer, Heart Failure (01:42:18) Genes, Lifestyle & Aging (01:47:54) Gray Hair Reversal, Stress; Inflammation & Aging (01:57:37) Energy Recovery, Sleep & Mitochondrial Function, Stress, Meditation (02:05:16) Tools: Yoga Nidra, NSDR; Pre-Sleep Relaxation, Energy & Restorative Sleep (02:10:58) Diet & Individualization, Clinical Trials; Mitochondria & Nutrition, Keto (02:20:14) Alcohol & Energy Budget; Stress (02:25:02) Exercise, Increase Mitochondria, Overtraining; Resistance & Growth (02:33:06) Sponsor: Waking Up (02:34:41) Supplements & Mitochondria Health, Deficiencies, SS31, Methylene Blue (02:41:31) Energy Flow & Experiences, Balance (02:49:13) Transform Through Resistance, Energetic Awareness, Connection (02:56:05) Food Overconsumption & Mitochondria Disruption; Tissues & Mitochondria (03:01:02) Mitochondrial Health Test; Tool: Ways to Increase Energy; Meditation (03:06:10) Peptides; Fertility Supplements, Urolithin A; Electromagnetic Fields (03:12:16) Acknowledgements (03:14:15) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices

Kim Ressler searched for answers to her chronic issues for years. Finally, a friend turned her on to the world of nutrigenomics. What if there was a way to genetically determine what kind of supplements would address your methylation pathways, your mental health and your ability to focus? During this year's Changing Life and Destiny conference in Dallas, Dr. Motley had a chance to sit down with Kim and learn how this works. Key Takeaways: Nutrigenomics bridges the gap between genetics and nutrition, allowing for personalized health strategies. Actionable genes can significantly influence our health and well-being, making genetic testing a vital tool. Customized supplements based on genetic insights can simplify health management and improve outcomes. Understanding our genetic makeup empowers us to make informed decisions about our health. There's even genetic information to find out how well you deal with hangovers as you get older.  Want more of the Ancient Health Podcast? Check out Doctor Motley's YouTube channel! ------  Follow Doctor Motley  Instagram TikTok Facebook Website Follow SNiP Nutrigenomics  https://www.instagram.com/snipnutrition/ https://snipnutrition.com/ https://www.youtube.com/@snipnutrition ------  * Do you have a ton more in-depth questions for Doctor Motley? Are you a health coach looking for more valuable resources and wisdom? Join his membership for modules full of his expertise and clinical wisdom on so many health issues, plus bring all your questions to his weekly lives! Explore it free for 15 days at https://www.doctormotley.com/15 *Most of us are mineral deficient and we don't even know it! Want to get your minerals in? BEAM Minerals is a simple shot of minerals each morning. Tastes like water, absorbs fast, and gives your body the full spectrum of minerals it needs. It's one of the easiest, most effective ways to support overall vitality. Try BEAM Minerals at beamminerals.com/DRMOTLEY and use code DRMOTLEY for 20% off your first order.

Music:Rooster by Ezra Sykes, 2014https://soundcloud.com/ezrasykes/the-rooster

El análisis de actualidad económica, todas las mañanas a las 07:30. 

Stieber pudo espiar a Marx. Durante casi todo el tiempo que este estuvo compilando Das Kapital, Stieber pudo llegar a Londres, espiar y compilar un informe sobre Marx.3a. y última parte de este interesantísimo articulo.

New trending diet? Crashing down your calorie levels? What does the ideal diet even look like?In this episode, Justin is joined by Ben Brown, founder of Body Systems — a program designed to boost your energy and support a healthy weight by helping you discover your unique body system blueprint. Ben once had extreme fatigue and an immune crash. He knew something was wrong, but chalked it up to having a new baby, working very early mornings and long days, as well as pursuing a second Master's degree on the weekends. He began questioning conventional fitness and nutrition advice, started listening to his body, and was able to overcome common immune-suppressing habits. He's on a mission to help men and women become the CEO of their health by building a body, a mindset, and a personal operating system using a science-based methodology.Justin and Ben tackle how diets work and fail based on their real-life experiences, and as well as stories from how they coach their clients. They discuss what the best way is to navigate through figuring out the right health choices which includes proper lifestyle, diet, nutrition, and rest - and balancing all of them as we live our daily lives.Here are the highlights of this episode:01:56 Ben's Wounded Healer Story08:06 Navigating Through Health Choices15:53 Keeping People in Check28:19 Recovery and Restoring Adrenal Capacity31:33 The Baseline35:38 Go-To's for Muscle Building41:29 Supplementation50:25 Switching Your MindsetIf you wish to learn more from Ben Brown and Body Systems, you may do so through the following channels:Website: www.bodysystems.comInstagram: https://www.instagram.com/bodysystemscoaching/YouTube: @bodysystemscoachingFacebook: @bodysystemsnutrition______________________________________________________Keep yourself up to date on The DNA Talks Podcast! Follow our socials below:The DNA Talks Podcast Instagram: @dnatalkspodcastThe DNA Company Instagram: @thednacoThe DNA Company's Official Tiktok Account: @thednaco3______________________________________________________Medical Disclaimer: The information provided in this communication is for general informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read here. If you think you may have a medical emergency, call your doctor or 911 immediately.Medical Disclaimer: The information provided in this communication is for general informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read here. If you think you may have a medical emergency, call your doctor or 911 immediately.

Wier has good genes/jeans HR 1 full 2271 Thu, 11 Dec 2025 16:54:35 +0000 r4d45izpq8B8LeITFnoMFvx6zKcIyIEx news MIDDAY with JAYME & WIER news Wier has good genes/jeans HR 1 From local news & politics, to what's trending, sports & personal stories...MIDDAY with JAYME & WIER will get you through the middle of your day! © 2025 Audacy, Inc. News False https://player.amperwavepodcasting.com?feed-link=https%3A%2F%2

A sperm donor whose genetic material was used to conceive nearly 200 children in at least 14 European countries has discovered he carries a mutation that increases the risk of cancer. Also, India's mango farmers are racing to adapt to changing markets and a changing climate. And, around 100 kidnapped Nigerian children have been returned to their families. Plus, a look at the politics behind written font types. Learn about your ad choices: dovetail.prx.org/ad-choices

(00:00-11:35) Is this the saddest song ever? This show gets in the way of people's jobs. Jackson loves The Scientist by Coldplay. Lots of sad songs getting sent in. Is SLUH an all girls school? Schwarber back with the Phillies.(11:43-21:48) No one said it would be this hard. What's the worst choice Doug has ever made? Sorry I asked. Stapling Clearsil pads to your head to combat baldness. Audio of Paul FInebaum saying nobody watches Notre Dame on NBC. College football TV deals. Audio of Jim Bowden talking about Jordan Walker's trade value and 'staying patient.'(21:58-27:12) E-Mail of the DaySee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

There is something incredibly liberating that happens when you realize your genes are not a life sentence. We have all been told that if a gene runs in your family, you're destined to live out the same story. Celiac. MTHFR. Hashimoto's. Breast cancer genes. We're taught to brace ourselves instead of learning how to influence the environment those genes live in. When the gut is overwhelmed, the immune system stays in a reactive state, and in that environment certain genes become more expressive than they would in a balanced body. And as the gut heals and the immune system steadies, those expressions often soften again.When we move through life in the energy of fearing our bodies, or resenting the parts of us that feel complicated or confusing, it creates a disconnect. Not just within us, but within our children. They feel it. They feel the way we brace around certain symptoms. They feel the heaviness we carry when we believe something is wrong with us, or wrong with them. Our energy teaches them what to believe about their own bodies, the world around them, and what is possible or impossible.If your child has a gene variant that society labels as undesirable, the most healing thing you can offer them is not fear. It's acceptance. It's steadiness. It's the belief that their body is not broken. Because when you hold that belief, they learn to hold it too.Your body is not something you need to fear. Your child's body is not something to fix. Every single part of you was designed on purpose. Every one of your gene variants is a page in your story. And when certain genes express, it is an invitation. It is your body communicating with you and bringing you back into alignment so you can show up in your life as the best version of you.. It is your body asking you to come closer, not pull away.When you view your body through this lens, everything shifts. You stop battling yourself. You stop bracing for what might happen. You begin partnering with your body instead of fearing it. And this is where your deepest power lives. In relationship. In understanding. In the environment you create on the inside.Your genes respond to you. They respond to the way you live, the way you nourish yourself, the way you support your gut and your nervous system, the way you speak to yourself, the way you choose to show up every day. And the more safety and nourishment you bring into your life, the more your genes settle into the expression that serves you.This is the freedom of gene expression. This is the empowerment that no lab report can ever take away from you. Thanks for listening! I would love to connect with you ♡ Subscribe to the Nourished Newsletter Explore the Gut Rebalance Kits Visit our FAQ's Follow along on a Instagram Take the free Gut Health Quiz Email us at customercare@onleorganics.com Sending love and wellness from my family yours,xx - Juniper BennettFounder of ōNLē ORGANICS

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El Gobierno de Victoria ha presentado una disculpa histórica a los pueblos de las Primeras Naciones, por las leyes, políticas y prácticas que han contribuido a las injusticias contra los aborígenes. Escucha el resumen informativo de este martes 9 de diciembre 2025.

La inmensa mayoría de los datos empleados en la elaboración del genoma humano y de todos los mapas relacionados hasta el momento proceden de personas de ascendencia europea. Este sesgo deja fuera variantes genéticas comunes en otras poblaciones, lo que socava la precisión y la equidad en la investigación genética y lleva a diagnósticos fallidos o tratamientos ineficaces en grupos que no estén representados. Hemos entrevistado a Pau Clavel-Revelles, investigador del Barcelona Supercomputing Center y el Centro de Regulación Genómica, coautor de un estudio que revela y cuantifica por primera vez esa falta de diversidad global en los mapas génicos de referencia.Con María González Dionis hemos recorrido la historia del virus del SIDA (VIH). La pandemia comenzó oficialmente en junio de 1981 con el primer grupo de casos detectado en EE.UU. pero el virus estuvo circulando durante décadas, desde África a América, sin ser detectado. Jesús Puerta nos ha hablado de la enigmática energía oscura y de una posible explicación para esa fuerza invisible que expande el universo: la presión negativa, una especie de anti-gravedad cósmica. Para llevar una vida sana hay que mantener una alimentación equilibrada y ciertos hábitos como hacer ejercicio. Pero como nos ha contado José Luis Trejo, cuidado con los excesos. Un ejercicio intenso, como una maratón, puede ser perjudicial para el cerebro. Adeline Marcos nos ha informado de un interesante proyecto europeo que pretende crear dispositivos electrónicos totalmente transitorios y biodegradables, es decir, diseñados para desaparecer al cabo de un tiempo al estar fabricados con materiales orgánicos. Con testimonios de Xavier Vilajosana, catedrático e investigador del grupo de Redes Inalámbricas de la UOC y coordinador del proyecto.Escuchar audio

The sequencing of genomes from archaic humans, such as Neanderthals and Denisovans, has transformed our understanding of human evolutionary history. These ancient genomes reveal that modern humans did not evolve in isolation but interbred with now-extinct groups, leaving lasting genetic legacies. To date, genomic sequences from 31 archaic human individuals, including four sequenced to high coverage, have provided unprecedented insights into the population structure, social organization, and adaptation of this now-extinct lineages, allowing us to reconstruct our own evolutionary history and the mechanisms that led to modern human success. Diyendo Massilani of Yale University School of Medicine reviews nearly three decades of research on archaic human DNA and what we have learned about how these groups lived, as well as how admixture between different lineages may have contributed both to the extinction of archaic humans and the thriving of modern humans. Ultimately, ancient genomes show that the success of our species was not predetermined but forged through encounters, exchanges, and adaptations, and that the legacies of archaic humans live on in our biology today, continuing to influence what it means to be human. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41193]

Dr. Marc Lewis is a neuroscientist, psychologist, and psychotherapist who taught developmental psychology at the University of Toronto for over 20 years. He's the author of "Memoirs of an Addicted Brain" and "The Biology of Desire: Why Addiction Is Not a Disease". Drawing from both his personal recovery journey and decades of research, Dr. Lewis offers a revolutionary perspective on addiction neuroscience.WHAT WE DISCUSSEDNEUROSCIENCE INSIGHTS:Why dopamine isn't a "pleasure chemical" and what it actually does in addictionThe real difference between healthy learning and addictive learningHow the striatum, amygdala, and prefrontal cortex create compulsive behaviorWhy different types of emotional pain lead to different substance choicesThe neuroplasticity principle: "what fires together, wires together"THERAPEUTIC PERSPECTIVES:Why addiction is NOT a chronic relapsing brain diseaseInternal Family Systems (IFS) therapy and how it heals addictionThe three parts: The Critic, The Firefighter, and The Exile (inner child)Why self-compassion is non-negotiable for recoveryHow to talk to the different "parts" of yourselfMark's approach with his 20-30 weekly therapy clientsPERSONAL WISDOM:Mark's 8-10 year journey through heroin and cocaine addictionHis daily practices for staying present and connected at age 74How he faced a terrible year (divorce, family estrangement, illness) with IFS toolsWhy connection (not sobriety) is the opposite of addictionPractical steps for breaking bad habits and building new neural pathwaysPARENTING & PREVENTION:How to talk to kids about drugs in a way they'll actually listenWhy loneliness is the biggest risk factor for addictionThe critical importance of movement, sleep, and feeling understoodWhy some childhood experimentation is actually healthyKEY INSIGHTS:"The opposite of addiction is not sobriety. It's connection" - Johann Hari"We have different parts of our personality, and they often polarize in addiction.""You can heal at any age—with presence, breath, and self-love.""Stop thinking of addiction as a disease. It's learned behavior."RESOURCES MENTIONEDBOOKSThe Biology of Desire: Why Addiction Is Not a Disease" by Marc Lewis (available in Romanian: "Biologia Dorinței")Memoirs of an Addicted Brain" by Marc Lewis"Chasing the Scream" by Johann HariPROGRAMS & PEOPLELiminal Learning program by Isabela Granic Dr. Gabor Maté - Compassionate InquiryDr. Dick Schwartz - Internal Family Systems (IFS) therapyJohann Hari's TED Talk: "The Opposite of Addiction is Connection"Sat Dharam Kaur - Compassionate Inquiry practitionerTHERAPIESInternal Family Systems (IFS)Compassionate Inquiry (CI)Acest episod este produs și distribuit cu susținerea E.ON Energie România. Episodul este creat în colaborare cu Compassionate Inquiry România, parte din inițiativa ReConnect 2025, un eveniment dedicat tratării și prevenirii adicțiilor. (00:00) Introduction(04:09) Mark's Journey: Addict → Scientist → Therapist(09:50) The Dopamine Myth Debunked(12:52) Addictive Learning vs. Healthy Learning(16:05) Why Some Get Addicted & Others Don't(19:59) Connection: The Opposite of Addiction(23:50) Genes vs. Environment in Addiction(29:20) The Most Important Thing Parents Can Do(36:50) How to Talk to Kids About Drugs(39:55) Different Pain = Different Addictions(46:53) The Neuroscience of Alcohol(51:21) Why Addiction Isn't a Disease(56:27) Different Paths to Recovery from Addiction(01:03:03) Internal Family Systems Therapy Explained(01:05:12) The Three Parts: Critic, Firefighter, Exile(01:07:52) Self-Compassion as the Engine of Healing(01:14:25) Processing Trauma Later in Life(01:17:50) Mark's Daily Healing Practices(01:21:33) The Science of Breaking Bad Habits(01:28:54) Can You Heal Without Self-Love?(01:34:59) Three Questions to Transform Addiction Treatment

Las revoluciones de 1848 fueron un gran éxito para Prusia. No solo habían aplastado la rebelión dentro de Prusia, sino que los reinos vecinos se derrumbaban bajo el peso de la “revolución obrera”.2da. parte de la continuación de esta interesante serie.

Are you interested in learning more about intermittent fasting? Join our expert clinicians, Dr. Lara Varden and Justin Harris, as we look at the science-backed benefits of intermittent fasting, from improved metabolic health to enhanced cognitive function, as our expert hosts delve into the latest research and practical applications.Gain valuable insights into how intermittent fasting can be a powerful tool for achieving optimal wellness. Whether you're new to fasting or looking to refine your approach, this session offers valuable information to help you harness the full potential of intermittent fasting.______________________________________________________Keep yourself up to date on The DNA Talks Podcast! Follow our socials below:The DNA Talks Podcast Instagram: @dnatalkspodcastThe DNA Company Instagram: @thednacoThe DNA Company's Official Tiktok Account: @thednaco3______________________________________________________Medical Disclaimer: The information provided in this communication is for general informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read here. If you think you may have a medical emergency, call your doctor or 911 immediately.

Katy & Jeannette dive into the question: can movement really change your DNA? Using clear analogies—like libraries, recipes, and sticky notes—they unpack what DNA is, how gene expression works, and what we really mean by epigenetics (the “on top of” changes that influence which genes get used). They explore how exercise can turn the “volume up or down” on metabolic genes, pro-inflammatory markers, and stress protein genes, and how many of these changes involve altering the arrangement and access to DNA within your cells.Using another accessible analogy of spider webs, they explore how forces on cells (through mechanotransduction) act as a powerful, non-chemical “nutrient” that can literally move your DNA and alter epigenetics and gene expression. This is why exercise and everyday movement not only have systemic benefits but also site-specific effects—and why the distribution of movement throughout your body matters just as much as how much you move.Enhanced Show Notes and Full Transcript00:00:23 “You can't change DNA”: Katy's green-room story with a physician who insists DNA is fixed.00:03:33 What is DNA? Jeanette's library-and-recipe analogy explaining DNA and gene expression.00:06:11 Genes as volume controls: How exercise turns gene activity up or down rather than rewriting DNA.00:12:02 Chromatin & compacted DNA: Archival library shelves as a metaphor for genes you rarely “reach for.”00:18:54 Mechanotransduction & spider webs: How movement plucks the cell's “web” and signals the nucleus.00:25:36 Epigenetics explained: Sticky notes, covered keyholes, and how markers sit “on top” of DNA.00:29:28 Epigenetic memory & trained vs. untrained leg study: Why movement has site-specific effects.00:32:17 Listener Question (sponsored by Movemate): Do organs such as the brain, liver, and kidney need specific movements?BOOKS & RESEARCH MENTIONEDMove Your DNA book by Katy Bowman Epigenetic profile of trained vs untrained leg  Walking & blood circulation to the brainPhysical Activity, Gut Motility & ConstipationCONNECT, MOVE & LEARNMovement Advent 2025: 24 Ball Exercises to Balance Tech StressJoin Our Newsletter: Movement Colored GlassesFollow Katy on SubstackTry Katy's Virtual Studio Free for 7 days!MADE POSSIBLE BY OUR WONDERFUL SPONSORS:Movemate: Active standing boards with smoothly articulating wooden slats. Designed to keep you moving without interrupting your focus. Take 15% off until Dec 7th with code MOVEMy Happy Feet: Toe-spacing socks that gently realign toes for comfortable recovery—take 20% off with code MYDNA.Ikaria Design: The Soul Seat® offers height-adjustable, multi-position sitting—get 10% off new chairs and desks with code DNA10.Venn Design: Stylish ball-shaped Air Chairs that encourage dynamic sitting—featuring in our 2025 Movement Advent! Peluva: Five-toe minimalist shoes that move like you do—take 15% off with code NUTRITIOUSMOVEMENT.Smart Playrooms: Beautiful playroom design and movement-rich equipment—save 10% on monkey bars and rock-wall items with code DNA10.Thoughts/questions email us at podcast@nutritiousmovement.comYour Voice on the Podcast: Read The Credits 

Sophie sits down with Erika Gray, co-founder of Toolbox Genomics, to break down how your genes affect detoxification, your ability to clear hormones, toxins, histamine, caffeine, and more.They talk about what happens when detox pathways run too fast or too slow, why environment matters just as much as genetics, and how understanding your unique blueprint can make detox and supplementation actually work better.Sophie also shares details about their new collaboration, where you can run your Detoxification Panel through Toolbox Genomics and get a personalized detox plan created just for you.Connect with Toolbox Genomics:toolboxgenomics.comWork with Sophie:shetalkshealth.comDisclaimer: This information is being provided to you for educational and informational purposes only. It is being provided to educate you about how to take care of your body and as a self-help tool for your own use so that you can reach your own health goals. It is not intended to treat or cure any specific illness and is not to replace the guidance provided by your own medical practitioner. If you are under the care of a healthcare professional or currently use prescription medications, you should discuss any dietary changes or potential dietary supplement use with your doctor, and should not discontinue any prescription medications without first consulting your doctor. This information is to be used at your own risk based on your own judgment. If you suspect you have a medical problem, we urge you to take appropriate action by seeking medical attention.

Send us a textWhen the brain gets knocked, it fights back—at least for a while. We open with new research that uses ALPS MRI to watch the glymphatic “waste rivers” of the brain as they surge after repeated head impacts and then falter when the system is pushed too far. That real-time look at fluid flow explains why early symptoms can be misleading and why rest, recovery windows, and better sideline calls aren't just policy—they're neuroprotection. We talk sports protocols, long-term risk, and how biomarkers could warn athletes before decline sets in.Then we lean into joy with rigor. Our pet science segment dives into a Cambridge study of more than a thousand golden retrievers showing that genes tied to trainability, fear of strangers, energy, and dog-to-dog aggression overlap with human genes for anxiety, depression, and intelligence. It's not destiny; it's sensitivity. We unpack how emotional regulation genes shape learning and coping, why some “bad” behavior is actually distress, and how training plans can be kinder and more effective when they support the nervous system, not just reward the behavior.To cap it off, we welcome John Reider,, the chief bubble dude behind Atomic Bubbles, for a whimsical masterclass in safe, scented bubbles for pets. He breaks down cosmetic-grade ingredients, water-soluble fragrances, and machine-friendly formulas that make durable bubbles dogs and cats actually chase. We explore lavender and pheromone-infused bubbles as floating diffusers for calming anxious pets, plus practical notes on storage, allergy concerns, and why bacon and peanut butter scents work without real allergens.Curious about brain health, dog behavior, and the science of pure fun? Hit play, subscribe for more smart, warm conversations, and share this episode with a friend who loves science—and their pets.ATOMIC BUBBLES with links to their socials!Here is the link to all our socials and stuff!!!Support the showFor Science, Empathy, and Cuteness!Being Kind is a Superpower. All our social links are here!

While we're taking a Thanksgiving holiday break this week, we're excited to share a special episode of Nice Genes! from our friends at Genome BC.  Our very own Jess joins Dr. Kaylee Byers as they dive into the fascinating world of wastewater surveillance. Along the way, they enlist a seasoned “poo detective,” Dr. Natalie Prystajecky, who wades through some wastewater 101, and how sewage can tip us off to disease outbreaks before symptoms even start. Then, Dr. Yemisi Bokinni brings the investigation to the not-so-small town of Makoko, Nigeria, where a new genome sequencing lab is chasing an old culprit: polio. From your neighborhood sewers to global health and future pandemics, we're using genomics to identify poo dunnit. For more episodes like this one, follow Nice Genes! wherever you listen. Follow on Apple Follow on Spotify Nice Genes! landing page Episode Resources 1. Wastewater Surveillance– BC Centre for Disease Control 2. Wastewater surveillance tells a quiet story of polio's return– BMJ 3. Nigeria's polio battleground'– Nature 4. Makoko: ‘Venice of Lagos'– SmartCities Dive Learn more about your ad choices. Visit megaphone.fm/adchoices

Why does groundbreaking research on mind-body medicine disappear without a trace? How do emotional factors create conditions for chronic illness and autoimmune disease decades later? What happens when a Harvard study shows severe PTSD doubles ovarian cancer risk—and the medical system simply ignores it? Dr. Gabor Maté joins me to discuss the writing process behind The Myth of Normal, his 19-week New York Times bestseller bringing together decades of research on trauma, nervous system dysregulation, and how emotional factors drive physical disease. We explore why mind-body unity—understood since Socrates 2,600 years ago—remains controversial in mainstream medicine despite overwhelming scientific evidence. Gabor addresses the most damaging misconception about his work: that he blames parents and patients. Whether we're trauma-informed practitioners, healing from chronic illness, or parents navigating guilt and shame, we'll understand why this conversation about mind-body medicine is finally reaching people—even when the medical system isn't ready.   In this episode you'll learn: [01:59] The Myth of Normal Journey: How 10 years of research and 20,000 articles became a 500-page synthesis of trauma biology [04:00] Writing for Critics Made Me Sick: Why trying to convince skeptics creates the very trauma biology we're studying [06:00] Harvard's 1939 Buried Truth: Soma Weiss's lecture on emotional factors equaling physical factors—and why it's still ignored [07:42] PTSD Doubles Ovarian Cancer Risk: Harvard study the average gynecologist never read—and what it means for trauma healing [09:40] People Are Ready, Systems Aren't: Why this trauma revolution is happening at the grassroots level first [13:53] New York Times Bestseller Doesn't Equal Happiness: The personal lesson about achievement and inner state [16:00] The Biggest Misconception: Addressing the damaging claim that Gabor blames parents and patients for illness [18:00] ADHD, Genes, and Environment: Why genetic sensitivity plus stressed parents creates attention dysregulation—without blame   Main Takeaways: Mind-Body Unity Isn't New Science: Socrates recognized 2,600 years ago that separating mind from body was medicine's fundamental error, and Harvard professor Soma Weiss lectured in 1939 that emotional factors equal physical factors in disease causation and healing. This isn't cutting-edge discovery—it's forgotten wisdom the medical system repeatedly buries. Scientific Evidence Disappears in the Bermuda Triangle: Hundreds of peer-reviewed studies demonstrate trauma's biological impact on chronic illness, autoimmune disease, and cancer risk, yet research doesn't change medicine when ideology creates blind spots. A Harvard study showed severe PTSD doubles ovarian cancer risk, but the average gynecologist never reads it. Empowerment, Not Blame, Changes Lives: Understanding that stress affects multiple sclerosis relapse risk or that the environment acts on ADHD genes doesn't blame patients or parents—it empowers them. Knowledge of how trauma creates conditions for illness provides agency to address root causes rather than remaining passive recipients of symptomatic care. Mitochondrial Dysfunction Extends the Mind-Body Framework: While The Myth of Normal covers mind-body unity comprehensively, Biology of Trauma® goes deeper to subcellular levels—showing how trauma affects mitochondria, cellular energy production, and the biology underneath symptoms.   Notable Quotes: "Socrates said 2,600 years ago in ancient Greece that the problem with the doctors today is they separate the mind from the body." "Emotional factors are at least as important in the causation of disease as physiological factors, and must be at least as important in the healing." (From the 1939 Harvard lecture) "You can have the same genes and have ADHD or not have ADHD. What makes the difference is how the environment acts on those genes." "Trauma is so ubiquitous in this culture and it's so poorly understood and addressed in the healing profession." "The change will happen at the level of people, not at the system. The people will demand the system change."   Episode Takeaway: What struck me most in this conversation with Gabor is how the desperate need to convince skeptical colleagues stems from our earliest attachment patterns where authority figures' opinions determined our safety. This is why writing to prove ourselves to critics creates the very nervous system dysregulation our trauma work addresses. Mind-body unity isn't revolutionary new science—it's 2,600 years of wisdom that mainstream medicine repeatedly buries. When Harvard published research in 1939 showing emotional factors equal physical factors in disease, and recent studies demonstrate severe PTSD doubles ovarian cancer risk, the medical system's silence isn't about lack of evidence but about ideological blind spots. The revolution happening now shows people are ready for this conversation even when systems aren't. As chronic illness increases, people seek understanding of how stored trauma, nervous system dysregulation, and emotional factors create conditions for autoimmune disease, cancer, and ADHD decades later. This isn't about blaming parents or patients—it's about empowering us with agency to address root causes. External achievement doesn't heal unresolved trauma, but the gratitude when we stop trying to convince critics and instead empower people with truth makes it worthwhile. We're catching a wave we're also generating. The system will change when people demand it.   Resources/Guides: Visit biologyoftrauma.com for more resources on the Biology of Trauma® framework The Biology of Trauma book - Available now everywhere books are sold. Get your copy Foundational Journey - If you are ready to create your inner safety and shift your nervous system, join me and my team for this 6 week journey of practical somatic and mind-body inner child practices. Lay your foundation to do the deeper work safely and is the pre-requisite for becoming a Biology of Trauma® professional.  Check out Dr. Gabor Maté's book, The Myth of Normal.  Related Episodes: Episode 39: How Does Trauma Manifest in the Body with Gabor Maté Episode 66: Gabor Maté: The Biology Piece We Have Missed In Trauma & Depression (Part 1) Episode 67: Gabor Maté: Healing Trauma and Chronic Illness Through Connection (Part 2)   Your host: Dr. Aimie Apigian, double board-certified physician (Preventive/Addiction Medicine) with master's degrees in biochemistry and public health, and author of the national bestselling book "The Biology of Trauma" (foreword by Gabor Maté) that transforms our understanding of how the body experiences and holds trauma. After foster-adopting a child during medical school sparked her journey, she desperately sought for answers that would only continue as she developed chronic health issues. Through her practitioner training, podcast, YouTube channel, and international speaking, she bridges functional medicine, attachment and trauma therapy, facilitating accelerated repair of trauma's impact on the mind, body and biology. Disclaimer: By listening to this podcast, you agree not to use this podcast as medical, psychological, or mental health advice to treat any medical or psychological condition in yourself or others. This podcast is for informational and educational purposes only and does not constitute professional advice, diagnosis, or treatment. Always consult your own physician, therapist, psychiatrist, or other qualified health provider regarding any physical or mental health issues you may be experiencing.  

Summary: The conversation delves into the significant privacy concerns surrounding the collection of DNA from newborns, particularly through whole genome sequencing. Dr. Nick Wilson and Leah Wilson, JD, discuss the implications of this practice, including the potential for a national genetic database and the ethical dilemmas it presents. They highlight the shift from traditional newborn screening to predictive genetic medicine, emphasizing the risks associated with genetic determinism and the importance of informed consent. The discussion also touches on historical lessons from gene therapy trials, the rise of biosurveillance, and the need for public awareness and action to protect individual rights and health outcomes. Takeaways: The purpose of newborn screening is shifting from identifying conditions to predictive analysis. Once genetic information is collected, it can be stored indefinitely. Genes are the least significant factor in health outcomes. The childhood vaccine schedule has expanded over time, raising concerns. The Newborn Screening Saves Lives Act could lead to a national genetic database. Parents need to be cautious about informed consent regarding genetic screening. Resources Mentioned: Reclaim Vitality, PRE-ORDER NOW ON AMAZON! One Dream on Instagram: @onedream.podcast — DM us your detox questions Follow The One Dream Podcast:

In this episode of Skin Anarchy, Dr. Ekta Yadav sits down with Simone Gibertoni, CEO of Clinique La Prairie, for the launch of our new Lessons In Longevity series. This is a powerful conversation about what longevity truly means today—and why it's no longer about “anti-aging,” but about living better, longer, and with intention. For nearly a century, the Swiss institution has been a leader in preventative medicine, and under Gibertoni's guidance, it has evolved into a global ecosystem built on personalized diagnostics, science-backed interventions, and deeply human care.Gibertoni shares how the rise of epigenetics has transformed our understanding of health, revealing that up to 80% of our outcomes are shaped not by genetics, but by lifestyle. At Clinique La Prairie, advanced testing—spanning epigenetics, metabolomics, and glycan mapping—guides individualized programs designed to shift habits, improve resilience, and create measurable change. But data, he insists, is only the beginning. “Information is not transformation,” he says. Real longevity comes from routines, structure, and the human relationships that support long-term growth.The clinic's Four Pillars approach—medicine, nutrition, movement, and well-being—reflects his belief that aging is multi-dimensional. Stress reduction, emotional vitality, and purpose are as essential as biomarkers. This philosophy extends into Holistic Health™, the clinic's line of precision supplements, including Epinone, formulated to support gene expression and cellular repair through structured, cyclical use.This episode reframes longevity as a mindset grounded in science, culture, and connection. Tune in to hear how Simone Gibertoni envisions a future where living well isn't a luxury—but a lifelong, human-centered practice.Learn more and shop Clinique La Prairie Holistic Health.CHAPTERS:0:02 – Introduction & Guest Welcome1:04 – The Origins of Longevity at Clinique La Prairie2:30 – From Anti-Aging to Longevity Philosophy3:31 – Genes, Epigenetics & Lifestyle Impact6:51 – The Longevity Process: Diagnostics, Intervention, Follow-Up9:26 – From Information to Transformation11:27 – The Four Pillars of Longevity13:26 – Closing the Gap Between Lifespan & Healthspan20:02 – Supplements, Science & The Future of LongevityPlease fill out this survey to give us feedback on the show!Don't forget to subscribe to Skin Anarchy on Apple Podcasts, Spotify, or your preferred platform.Reach out to us through email with any questions.Sign up for our newsletter!Shop all our episodes and products mentioned through our ShopMy Shelf! Hosted on Acast. See acast.com/privacy for more information.

What can genetics and palmistry tell us about how we understand identity, character and health? Adam Rutherford is joined by Professor of Zoology Matthew Cobb; the historian Professor Alison Bashford and the geneticist Charlotte Houldcroft.Matthew Cobb discusses his biography Crick: A Mind in Motion. From the discovery of DNA's structure to Francis Crick's later work on consciousness, Cobb reveals a restless thinker whose collaborations — with scientists, artists and poets — shaped some of the most profound ideas of the 20th century.Alison Bashford turns to palm reading in her new book Decoding the Hand, a history of palmistry and its surprising entanglement with science, medicine and magic.The geneticist Charlotte Houldcroft's research uses ancient DNA to work out how DNA viruses - such as smallpox and herpes - change over time and the consequences of this evolution for our immune systems.Producer: Natalia Fernandez

In this Huberman Lab Essentials episode, my guest is Dr. David Sinclair, PhD, a professor of genetics at Harvard Medical School and a leading expert on the biology of aging. We discuss the cellular and molecular mechanisms of aging—and how specific behaviors, such as fasting, regular exercise and NAD⁺-boosting compounds like NMN, can activate the body's natural longevity pathways. This discussion highlights how lifestyle choices profoundly influence the aging process and may even slow or reverse key aspects of biological aging. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AGZ by AG1: https://drinkagz.com/huberman David: https://davidprotein.com/huberman Eight Sleep: https://eightsleep.com/huberman Timestamps (0:00) David Sinclair (0:20) Longevity, Anti-Aging, Aging as a Disease (2:27) Causes of Aging; Epigenome & Genes (4:53) CD & Scratches Analogy, DNA, Silencing & Expressing Genes (6:44) Physical Appearance & Aging (7:36) Sponsor: David (8:54) Childhood Development & Aging, Horvath Clock, Accelerate Aging (11:30) Rates of Puberty & Aging, Growth Hormone (12:37) Body Size & Longevity; Epigenetics (13:07) Fasting, Calorie Restriction & Longevity, Sirtuins, Insulin & Glucose (16:31) Tool: Skip a Meal (17:07) Longer Fasts & Autophagy, “Deep Cleanse” (18:07) Sponsor: AGZ by AG1 (19:36) Fasting, Fluids, Electrolytes (20:16) Sirtuins, Glucose, mTOR & Fasting; Leucine, Tool: Pulsing Behaviors (24:24) Breaking a Fast, Tools: Do Your Best; Transitions (27:00) Sirtuins, NAD, NMN Supplementation (29:04) Sponsor: Eight Sleep (31:10) Iron & Senescent Cells; Personalize Medicine (32:40) Tool: Blood Markers, CRP (34:50) Tool: Aerobic & Resistance Exercise (35:55) Estrogen, Fasting & Fertility; Aging & Rejuvenation (38:20) Acknowledgements Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices