Podcasts about genes

-Evento CB en Madrid (Centro Cultural Eduardo Úrculo, Tetuán), 19/9 a las 13h (05:00)-Genes parálogos universales antes de LUCA (12:30)-Mercurio, el planeta menguante (45:20)Contertulios: Borja Tosar, Ignacio Crespo, Juan Carlos Gil, Francis Villatoro, Héctor SocasLa tertulia semanal de la actualidad científica. En la web: https://señalyruido.comEn el episodio de hoy: Hosted on Acast. See acast.com/privacy for more information.

Las fotografías obtenidas por la cadena CBS muestran aviones destruidos, remolques aplastados y edificios gravemente dañados en bases de Arabia Saudita y Kuwait.

Hoy contamos con la presencia de Josue Villanueva de Quimbao La Nuit, con premios y buenos profesionales... además Achamán nos invita a la cita anual en las Festividades de El Cristo de La Laguna teniendo como invitados a Los Gofiones. Las Libreas salen desde El Palmar a Geneto, Pepe desde El Palmar nos cuenta su trabsjo y Paulino en Geneto nos lleva además a unas jornadas culturales. También vuelve el Festival anual Cirilo El Tamborilero con el grupo Atenguajosy el Reislas comienza a rodar,  por eso conversamos con Darío López. Y como cada semana nos vamos a escena con Zálatta Teatro... todo en La Diez Capital Radio con Joam Walo "poniendo lo canario más de moda que nunca y apostando por lo nuestro" 

In his first conversation with Paul, Mark Wolynn shared his personal journey that led him to become a renowned authority on inherited trauma and write a best-selling book about it. Mark returns to talk about his recently revised landmark book, It Didn't Start With You, and a new workbook that accompanies it and to describe how our DNA and genes are affected by trauma across generations this week on Spirit Gym.Learn more about Mark and his Inherited Family Trauma Training Program and workshops along with booking a private session with him on his website. You'll also find him on Facebook and Instagram. If you need help, contact Giovanna Taormina for a list of practitioners Mark has trained.Timestamps9:13 Despite writing a book on generational trauma, Mark's work with clients mainly focuses on attachment trauma.11:02 “Throw away the old book!”18:45 While some pay attention to attachment styles, Mark looks at breaks between people and how they function.25:27 Describing generational trauma.32:00 The first case that taught Mark how to look for inherited family trauma and changed his life 30 years ago.40:57 Where does this deeply traumatic information reside?49:12 How our DNA and genes are affected by trauma across generations.52:49 Mark describes the trauma experience from a spiritual perspective.1:03:50 Mark's psychotic break at age 24 was the beginning of his healing and how he began helping others.1:08:45 Mark regains his eyesight after healing his trauma inherited from his mother and grandparents.1:12:36 Paul's inherited trauma.1:24:27 How many generations of inherited trauma could humans carry?1:32:19 “Our inhumanity toward others is often a mirror of our own inhumanity toward ourselves.”1:42:04 Mark's core sentence tool in action.1:49:37 Positive traits can be transferred and inherited among generations too.1:56:31 Examples of verbal and non-verbal trauma language.2:01:31 Mark's The Official It Didn't Start With You Workbook is designed to be used whether you read his book or not.2:13:16 Every day, take a few moments to pause and take inventory of what you're feeling and, especially, the divine nature within you.ResourcesIt Didn't Start With You by Mark WolynnThe Official It Didn't Start With You Workbook by Mark WolynnTrichotillomaniaThe work of Bert Hellinger, Dr. Isabelle Mansuy and Dr. Rachel YehudaPaul's podcast conversation with Diane Poole HellerMorphic Resonance and Morphic Fields: An Introduction by Rupert SheldrakeHealing With Haiku: A Poetic Exploration of Self by Anne HelferBrainstorm: The Power and Purpose of the Teenage Brain by Dr. Daniel SiegelThe Biology of Transcendence by Joseph Chilton PearceA Practical Guide to Vibrational Medicine: Energy Healing and Spiritual Transformation by Richard GerberFind more resources for this episode on our website.Music Credit: Meet Your Heroes (444Hz), Composed, mixed, mastered and produced by Michael RB Schwartz of Brave Bear MusicThanks to our awesome sponsors:PaleovalleyBIOptimizers US and BIOptimizers UK PAUL15Organifi CHEK20CHEK InstituteWe may earn commissions from qualifying purchases using affiliate links.

In Monday's episode of Dennis AMA, Dennis Prager lets listeners set the agenda with questions pulled from October and November 2004, covering everything from faith and family to parenting, music, books, and the unexpected lessons of everyday life. Dennis discusses why Jewish evangelism largely disappeared after centuries of persecution and isolation, the relationship between Judaism and Christianity, and his vision for a Jewish Christian alliance. He also has a touching conversation with a young Christian school student who recites the Shema in Hebrew. The conversation turns to parenting as Dennis advises a father struggling with his son's school performance. He discusses grades, discipline, school choice, reading, and why children should not be defined solely by their academic achievements. Dennis also shares a remarkable story from a serious car accident in his youth, talks about his love of music and Bible translations, and gets an unexpected lesson in how to properly adjust car mirrors to eliminate blind spots. The episode concludes with a powerful reflection on family heritage, adoption, and what parents truly pass on to their children. For Dennis, values matter more than blood, and the legacy we leave our children is ultimately about what we teach them and how we influence the people they become. Follow on Apple Podcasts: https://podcasts.apple.com/us/podcast/timeless-wisdom-with-dennis-prager/id1517302239 Follow us on Spotify: https://open.spotify.com/show/4SZEYeH4tuLr2FvG4ok1rl Learn more about Dennis Prager: https://pragertopia.com/ Follow Dennis on Facebook: https://www.facebook.com/DennisPrager Follow Dennis on Instagram: https://www.instagram.com/thedennisprager/ Follow Dennis on X: https://x.com/DennisPrager Learn more about the Salem Podcast Network: https://salempodcastnetwork.com/ Discover more Christian podcasts at lifeaudio.com and inquire about advertising opportunities at lifeaudio.com/contact-us.

Twenty years ago, roughly eight scientific papers a year were being published on the gut microbiome. Scientists barely knew it existed. Today it is one of the most actively researched areas in all of human biology, and what it's revealing is that this community of trillions of microbes living in your lower intestine is not just relevant to digestion. It's connected to your immune system, your brain, your metabolism, your mood, your response to stress, and your long-term risk of many major diseases.In this episode of the Food Matters Live podcast, recorded at our London Olympia event, two scientists approach the gut microbiome from very different angles. Dr Emily Leeming, microbiome scientist, registered dietitian and author of Genius Gut and Fibre Power, opens with a compelling and accessible masterclass on what the gut microbiome is, why it matters, and what we can actually do about it. Dr Umar Jan, President of European Operations at Sabinsa, then presents the science behind two of Sabinsa's biotics. His presentation addresses a question that sits at the heart of the postbiotic category: when you inactivate a probiotic, what exactly are you left with, and can you prove it's doing something useful?If this has whet your appetite for next year's Food Matters Live events - you can already register your interest to partner with us in London and Rotterdam. Just head to foodmatterslive.com

In this season 8 opener Rosy shares both her experience recovering from bipolar disorder and the heartbreak of watching her beloved son begin to show signs of an even more extreme form of bipolar disorder called schizoaffective disorder. This is a story in parallel, two lives deeply intertwined, yet also slowly tearing apart as her son's illness became increasingly severe.Support the showElemental Psychedelicshttps://www.elementalpsychedelics.com/Explore every episode through themes, domains, formats, and speakers. The BFTA CODEX is a listener-built and curated field guide to the podcast. https://bfta-codex.orgBFTA episode recommendations/Podcast pagehttps://www.craigheacockmd.com/podcast-page/BFTA on IG @backfromtheabysspodcasthttps://www.instagram.com/backfromtheabysspodcast/Support the show

In this Huberman Lab Essentials episode, my guest is Dr. Oded Rechavi, a professor at Tel Aviv University who studies genetics, epigenetics and the inheritance of acquired traits. We discuss how DNA, RNA and epigenetic mechanisms determine what information can pass between generations, and why acquired traits are generally not thought to be inherited. We also explain research in C. elegans showing how small RNAs can transmit antiviral resistance and influence behavior across generations, what these findings might mean for mammals and humans, and potential future applications for reproductive health and diagnostics. Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps (00:00:00) Oded Rechavi (00:00:24) DNA, Genome, RNA & Proteins (00:03:43) Somatic vs. Germ Cells; Inheritance (00:06:05) Sponsor: Eight Sleep (00:07:23) Lamarck vs. Darwin, Inheritance of Acquired Traits (00:09:45) Weismann Barrier, Epigenetic Reprogramming (00:13:05) RNA & Transgenerational Inheritance (00:13:54) Model Organisms, C. elegans (00:16:59) Inheritance of Acquired Traits in C. elegans (00:17:14) Sponsor: AG1 (00:18:40) RNA Interference, Small RNAs & Gene Silencing (00:22:46) Viral Resistance Across Generations (00:24:53) Small RNAs, Mammals & Inherited Effects (00:26:00) Brain Activity, Memory & Heritable Information (00:28:46) Neuronal Small RNAs & Behavior Across Generations (00:29:59) Germ Cells, Development & Heritable RNA (00:31:29) Sponsor: LMNT (00:33:11) Future Applications, Exercise, IVF & RNA Diagnostics (00:35:16) Acknowledgements Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of the Health Optimization Medicine Podcast, Dr. Ted Achacoso, Dr. Jup Kuipers, Boomer Anderson, Dr. Allen Bookatz, and Dr. Scott Sherr explore a difficult question: can we influence the biology of an aging brain carrying APOE4 risk? APOE4 is not simply a diagnosis, and a genetic result does not tell us what is happening in someone's brain today. The team looks at how APOE4 may affect lipid transport, microglial behavior, vascular integrity, glucose utilization, mitochondrial function, circadian biology, and epigenetic maintenance. The discussion also lays out a practical three-phase framework: establish the phenotype, reduce ongoing stressors, restore circadian and bioenergetic alignment, and track whether cognitive, functional, metabolic, vascular, and biological age measures actually improve over time. Join us as we delve into: APOE4 Risk vs Diagnosis: What one versus two APOE4 copies may mean, and why genotype is not the same as the current clinical stage. Cellular Energy and Epigenetic Maintenance: Why disrupted energy metabolism can affect the conditions needed for normal transcription and epigenetic maintenance. Circadian Biology, NAMPT and NAD+: How CLOCK and BMAL1 influence NAMPT and the NAD+ salvage pathway, and why disrupted circadian rhythms can affect cellular maintenance. Health Optimization Medicine vs Disease-Centered Prevention: Why the HOMe approach focuses on the cellular environment and the conditions that create and sustain health. The Three-Phase Clinical Framework: How to establish a baseline phenotype, reduce exposomic stressors, restore circadian and bioenergetic alignment, and track outcomes over time. The Skeptical Position: The team considers the argument that APOE4-driven pathology may be too genetically determined for lifestyle and metabolic tuning to meaningfully change the trajectory. What Does a "Reset" Actually Mean?: Why a reset is a claim that needs to be demonstrated through durable improvements in cognition, function, and biomarkers over time. This episode is for you if: You have undergone genetic testing and want to better understand what an APOE4 result does and does not tell you. You are interested in the relationship between APOE4, brain aging, metabolism, vascular health, and mitochondrial function. You want to understand how circadian biology, NAD+ salvage, and epigenetic maintenance may intersect with brain health. You are interested in a measurement-based Health Optimization Medicine approach to genetic risk. You want to understand why phenotype, longitudinal tracking, and objective biomarkers matter when evaluating interventions. You can also find this episode on… YouTube: https://youtu.be/byEspMGRbtI Find more from Health Optimization Medicine and Practice (HOMeHOPe): Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ HOMeHOPe Conference 2026: https://homehope.org/homehope-conference-2026 Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://homehope.org/products/clinical-metabolomics Find more from Troscriptions: Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://troscriptions.com/collections/our-products

Episode: 2927 Dual Inheritance Theory: How our Genes and our Culture are co-evolving.  Today, let's talk about cultural complexity.

Árboles misteriosos, tigres al acecho y comportamientos de caza poco comunes de los delfines han sido algunos de los temas destacados en los Mangrove Photography Awards (Premios de Fotografía de Manglares) 2026.

En Orígenes hoy hablamos del Festival de Folclore de la Agrupación Folclórica Farutes en Santa Cruz de Tenerife, también nos fuimos hasta Icod de los Vinos y hablamos de La Librea de las Angustias, salen los Diablos a la calle este fin de semana. Hasta Chile viajamos y hablamos con Gofiorina, una enamorada de Canarias, que sin conocerla, une ambas culturas con sus semejanzas. Y vuelve el Festival de Zarzuela a Gran Canaria, son 34 temporadas y Lionell Sánchez de la Fundación Alejandro Da Silva, pedalea por Canarias en el Reto Ciclista GRAN GUANCHE, contra la leucemia. Todo en La Diez Capital Radio con Joam Walo "poniendo lo canario más de moda que nunca y apostando por lo nuestro" #ladiezradio #origenes #programaorigenes #joamwalo

This episode breaks down the difference between genetics and epigenetics — the genes you're born with versus the environmental and experiential factors that switch those genes on or off. The conversation explores how stress, trauma, and lifestyle can alter gene expression without changing the underlying DNA sequence itself, and what that means for understanding mental health and behavior. It's a foundational look at why "nature vs. nurture" is really a false choice, and how the two are constantly interacting.

¿Puede una idea colectiva adquirir tanta fuerza que termine dominando a toda una sociedad? En este video analizamos el concepto de egrégor y el nazismo como uno de los casos históricos más extremos para estudiar la relación entre símbolos, rituales, mitología, propaganda y psicología colectiva. A lo largo del video exploramos qué es un egrégor desde la perspectiva de determinadas tradiciones esotéricas: una forma de pensamiento colectivo alimentada por las emociones, creencias, símbolos y acciones de un grupo. A partir de esta idea, estudiaremos cómo una identidad colectiva puede reforzarse mediante líderes, rituales, consignas, símbolos y narraciones compartidas. Uno de los puntos centrales será el ensayo Wotan de Carl Gustav Jung y su interpretación psicológica del ascenso del nacionalsocialismo. Jung relacionó los acontecimientos de Alemania con la reactivación simbólica de Wotan u Odín y con fuerzas procedentes del inconsciente colectivo. También viajaremos a las raíces intelectuales y culturales anteriores al Tercer Reich: el movimiento völkisch, el concepto de Volkskörper, la doctrina de “sangre y suelo”, la ariosofía, Guido von List, Jörg Lanz von Liebenfels, la Germanenorden y la Sociedad Thule. Veremos cómo antiguas imágenes y tradiciones germánicas fueron reinterpretadas y utilizadas dentro de nuevas construcciones ideológicas. Analizaremos además la enorme influencia cultural de Richard Wagner, sus mitos germánicos y la utilización posterior de figuras heroicas como Sigfrido dentro del imaginario nacionalista

The Tenpenny Files – Kashif Khan explores how genetics influence detoxification, metabolism, sleep, stress, supplements, relationships, and healthy aging, revealing why identical health advice can produce different results. His functional genomics approach encourages people to understand their unique biological instructions before choosing diets, treatments, or wellness protocols for themselves...

Podcast Hosts:Grant Broggi: Marine Veteran, Owner of The Strength Co. and Starting Strength Coach.Jeff Buege: Marine Veteran, Outdoorsman, Football Fan and LifterTres Gottlich: Marine Veteran, Texan, Fisherman, Crazy College Football Fan and LifterJoin the Slack and Use code OKAY:⁠https://buy.stripe.com/dR6dT4aDcfuBdyw5ks⁠Check out BW Tax: ⁠https://www.bwtaxllc.com⁠BUY A FOOTBALL HELMET:⁠⁠⁠⁠https://www.thestrength.co/mrhelmet/?utm_source=The+Okay+Podcast&utm_medium=Podcast&utm_campaign=Okay_Pod⁠Grant's wife is in labor, the due date is TODAY, and we recorded anyway — because the slide deck was full and the trash must be secured. Episode 0125 opens with a full Trash Battalion staff meeting (awards board voting, BLUF violations, 0530 trash bag training, and a surprisingly moving word from Chaps) before the guys get into the real intel: where's the line on American flag apparel? Crocs? Socks? Underwear? Tres draws his line and it involves not trusting his own farts.Then Grant reports from Newport, Rhode Island on the greatest chow value in New England — the Two Bug Lunch — two whole lobsters, corn, and coleslaw for $40. Jeff finally stops gatekeeping Patagonia's tinned fish (a canned fish company that makes clothes), and Grant explains whether genetics actually matter for getting strong.Plus: Week Zero college football (USC's crowd of dozens), Week 1 speed picks, the guys make their official picks on the baby's arrival date, time, and weight, and the episode closes with the definitive air power vs. sea power doctrine book-off. It's only a lot of reading if you do it.Timestamps: 00:00 - Intro04:38 - Staff Brief23:41 - Chaps Calls In28:46 - Tres' Lifting Update28:53 - Wearing The Flag Debate34:34 - America 250th Plate Update36:32 - Two Bug Lunch41:00 - Tinned Fish47:02 - Role of Genetics In Lifting01:07:03 - Week Zero Recap01:13:50 - Due Date Predictions01:17:47 - Week One Picks01:23:07 - NIL Chaos01:25:45 - Hung Ordinance

Genes are just one factor in your odds for developing Alzheimer's disease. A study from the Center for Health Disparities Research at UW–Madison explores the environmental and societal factors behind the disease. It's a mission that is supported by a $30.9 million grant from the National Institutes of Health. CHDR director Dr. Amy Kind joins host Bianca Martin and executive producer Hayley Sperling to explain what we now know about Alzheimer's disease and external factors. Then, the team discusses the uncertain future of legal hemp-derived cannabis in Wisconsin as the Nov. 11 federal ban looms. Plus, Badgers head to class today! As UW-Madison alumni, Hayley and Bianca sound off with their hot tips for new students.

It is the final sequence of "Bad Genes" Month here in the Spoiler Room. This time we take a look at a film that can fit into many genres. Join us as we discuss the smart script, practical F/X, the talented cast, and more. Tune in.Jeff York's Website: https://www.theestablishingshot.org

If you're a woman over 40 wondering why your body suddenly feels different—even when your lab results say everything is “normal”—this episode of the V.I.B.E. Living Podcast may help you look at your health in an entirely new way.Poor sleep. Unexplained fatigue. Inflammation. Low energy. Mood changes. A body that no longer responds to the healthy routines that used to work.For many women navigating perimenopause, menopause and midlife, the question becomes: What is my body trying to tell me?In this fascinating conversation, Lynnis Woods-Mullins sits down with Kim Ressler, founder and CEO of Snap Nutrigenomics, to explore how nutrigenomics, genetic testing and personalized nutrition may provide another piece of the wellness puzzle.Kim shares her own 11-year search for answers and how understanding her genetics finally helped connect some of the dots.Together, we break down nutrigenomics in everyday language and explore how genetic variations may influence the way your body processes nutrients and supports pathways related to inflammation, oxidative stress, detoxification, immune function and vitamin D.You'll also discover why taking more supplements isn't necessarily better—and why a more personalized approach to supplementation may help eliminate some of the expensive guesswork.We dive into:Methylation, folate and folic acid and why the differences may matterHow genetics may provide additional context for concerns involving energy, mood and overall wellnessThe difference between information from DNA testing, blood work and hormone panelsWhy your current lab results represent a moment in time while your inherited DNA remains largely stableHow personalized nutrition and supplementation may help you make more informed wellness decisionsImportant questions to ask before genetic testing about privacy, data sharing, sample storage and biobankingAnd here's the good news: you don't need genetic testing to begin supporting your health today.We close with simple, powerful wellness foundations that can support women throughout midlife and healthy aging: prioritizing quality sleep, making sustainable nutrition changes, moving your body consistently, managing stress and staying connected to community.If you're between 45 and 55 and navigating perimenopause, menopause, fatigue, inflammation, changing nutritional needs or simply the feeling that your body isn't working quite the way it used to, this conversation is especially for you.Your body isn't asking you to give up.It may simply be asking you to pay attention differently.

What happens when you're doing everything you think is healthy, but your body keeps telling you something is wrong? In Part 2 of this special sister series, Susan sits down with Leslie to share her deeply personal journey from exhaustion, weight gain, brain fog, hormone struggles, and constant self-diagnosing to finally understanding what her individual body needed.Leslie had spent years immersed in natural health, researching symptoms and trying to make informed choices. But by the time she came to Susan, she was exhausted, taking two- to three-hour naps, struggling to think clearly, gaining weight despite her efforts, and navigating hormone therapy that wasn't addressing the complete picture- and making things worse. By looking at Leslie's genetics, labs, lifestyle, stress response, metabolism, hormones, and nutrition together, they uncovered connections that had previously been missed. Today, Leslie is 37 pounds down, no longer relying on daily naps, has significantly more energy, and feels like she has her life back. Her story is a powerful reminder that knowing what is generally “healthy” is not the same as knowing what is healthy for YOU.In This Episode:Why years of researching and self-diagnosing her health eventually left Leslie exhaustedHow hormones, insulin resistance, thyroid function, stress, and genetics were contributing to her symptomsWhy foods and habits considered “healthy” weren't necessarily supporting Leslie's individual biologyHow personalized nutrition and lifestyle changes helped her lose 37 pounds without starving herselfWhy maintaining her progress through an incredibly stressful month became one of her biggest measures of successHow her energy, digestion, daily routines, and overall quality of life have transformedRESOURCES:Connect with Leslie Adamson:https://trinityanchoredformation.com/Find all of Susan's Resources and links in the show notes: https://healthyawakening.co/2026/08/31/episode138/Connect with Susan: https://healthyawakening.co/Visit the website: healthyawakening.co/podcastFind listening links here: https://healthyawakening.co/linksP.S. Want reminders about episodes? Sign up for our newsletter, you can find the link on our podcast page! https://healthyawakening.co/podcast

Multiomics: The Next Frontier In Precision Medicine And Diagnostics Standard blood tests aren't giving you the most accurate picture of your health. Our expert examines the critical blind spots in standard medical testing and reveals emerging technology that catches disease at the cellular level. Guest: Dr. Adrijana Kekic, CEO & founder, Futurome Host and Producer: Kristen Farrah   Closing The Info Gap: A New App That's Empowering Patients And Caregivers Patients routinely forget up to 80 percent of the information shared during a doctor's appointment. Thankfully, a new app puts control directly back into the hands of patients by bridging this critical information gap and eliminating the stress of lost instructions. Our expert explores how empowering individuals with clear, accessible records of their care can transform the patient experience and relieve burnout for healthcare providers. Guests: Dr. Arpan Parikh, psychiatrist, CEO & co-founder, Kin Health Host: Greg Johnson Producer: Kristen Farrah Facebook: ingoodhealthpodX: @ ingoodhealthpodIG: @ingoodhealthpodYouTube: @ingoodhealthpodSpotify Apple Podcast In Good Health PodcastSubscribed to the newsletterFull ArchiveContact UsBecome an Affiliate Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Multiomics: The Next Frontier In Precision Medicine And Diagnostics Standard blood tests aren't giving you the most accurate picture of your health. Our expert examines the critical blind spots in standard medical testing and reveals emerging technology that catches disease at the cellular level. Guest: Dr. Adrijana Kekic, CEO & founder, Futurome Host and Producer: Kristen Farrah Facebook: ingoodhealthpodX: @ ingoodhealthpodIG: @ingoodhealthpodYouTube: @ingoodhealthpodSpotify Apple Podcast In Good Health PodcastSubscribed to the newsletterFull ArchiveContact UsBecome an Affiliate Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

El Arca de la Alianza ha infundido durante siglos un temor reverencial. Se decía que poseía poderes extraordinarios: hacer aparecer alimentos, derribar muros o comunicarse directamente con Dios. ¿Eran estos poderes realmente divinos, o quizá el Arca fue en realidad un artefacto de tecnología avanzada? Además, se afirma que otros objetos misteriosos, como el anillo de Salomón, tenían la capacidad de controlar fuerzas sobrenaturales. Un disco solar de origen inca podría haber sido un instrumento para comunicarse con reinos ignotos. De forma similar, a la enigmática calavera de cristal de los mayas se le atribuye la función de ser un antiguo dispositivo de almacenamiento de información. ¿Y si estos objetos legendarios nos ofrecieran pistas sobre la posibilidad de que las civilizaciones antiguas poseyeran conocimientos tecnológicos muy superiores a los que imaginamos? ¿Y si fueran, en realidad, poderosos dispositivos de un pasado extraterrestre ya olvidado?

In this Podcast of Hello Doctor, Dr. Sunil Gupta explained that diabetes is often a silent disease, with many people remaining undiagnosed for years. He discussed the different types of diabetes, the warning signs, and the importance of early screening—starting from 30 years of age for individuals with a family history and 35 years for everyone else. He also highlighted that Indians are genetically more prone to diabetes, obesity, hypertension, and heart disease, making regular health check-ups, healthy eating, and physical activity essential for prevention. Dr. Gupta also answered listeners' questions on diabetic neuropathy, obesity, insulin resistance, prediabetes, and diabetes prevention. He emphasized that good control of blood glucose, blood pressure, cholesterol, regular monitoring, and timely treatment can significantly reduce the risk of complications such as nerve damage, foot ulcers, heart attack, stroke, and kidney disease. He stressed that lifestyle modification remains the cornerstone of diabetes prevention and management. Concluding the programme, Dr. Gupta described the four pillars of diabetes care—healthy diet, regular exercise, medications, and glucose monitoring—while emphasizing that the most important foundation is diabetes education and patient empowerment. Acting as the “Table Top” of the four pillars. He encouraged greater awareness in schools, workplaces, and communities, reminding listeners that "Genes are the loaded guns; the environment pulls the trigger," making healthy lifestyle choices the key to preventing diabetes and living a healthier life. Expert- Dr Sunil Gupta Anchor- Manjusha Ambulkar Podcast: 30/07/2026 Recorded at: Akashwani Nagpur

In this episode of Discovery Matters, new research using the Swedish Twin Registry reveals that genetics may account for up to 50% of intrinsic lifespan, far more than previously thought. Associate Professor Sara Hegg (Karolinska Institutet) explains what heritability really means, why earlier models underestimated genetics, and what this does (and doesn't) mean for lifestyle, biohacking, and aging interventions. The result: a more nuanced view of how biology, chance, and choice shape how long we live.

Déjame tu comentarioEn este episodio hablamos sobre la guerra en Ucrania y el llamado del arzobispo Sviatoslav Shevchuk a no olvidar el valor de la libertad. También exploramos cómo la libertad está unida a la verdad, la responsabilidad, la misericordia y, sobre todo, al amor a Dios y al prójimo. Finalmente tendremos un análisis de las diversas imágenes distorsionadas que creamos de Dios. Redes sociales: saulmarrerorivera (Facebook e Intagram)Correo electrónico: notasdefeyvida@gmail.comDirección postal: 189 Ave Las María apart 305, San Juan PR, 00927-4325Música: bensound.comSupport the show

In this episode of Behind the Genes, we explore how personalised cancer vaccines are being developed, and how genomics and AI could help make these treatments more precise.  Our host, Florence Cornish is joined by:  Dr Victoria Goss, Associate Professor of Early Diagnosis and Translational Research at Southampton Clinical Trials Unit and head of the Southampton Clinical Trials Unit Cancer Vaccine Launchpad team  Professor Lennard Lee, Associate professor at the University of Oxford, Consultant Medical Oncologist, NHS  Ali Richards, a participant who took part in a cancer vaccine clinical trial  Together they discuss how cancer vaccines train the immune system to recognise cancer, how genomic information can help identify the unique features of an individual's tumour, and how AI could help researchers analyse genomic data and accelerate the development of new cancer vaccines.   “The reason I said yes was because my treatment really was punishing. It was so many side effects to it. The cancer never made me feel sick, but the treatment made me really sick. So I said yes because I just wanted to help other people not have to go through what I went through.”    Transcript [00:00:00] Florence: What if a vaccine could help treat cancer? Hello and welcome to Behind the Genes, the podcast that brings you the stories, research, and innovations shaping the future of genomic healthcare. Today, we're going to be talking about cancer vaccines, how they're being developed with the help of AI, what role genomics has to play, and what it could mean for patients.  [00:00:23] Florence: I'm Florence Cornish, and joining me today we have Dr Victoria Goss, who leads cancer vaccine research at Southampton Clinical Trials Unit; we have Professor Lennard Lee, who is a medical oncologist and Associate Professor at the University of Oxford; and Ali Richards, who took part in the Southampton Cancer Vaccine Programme.  [00:00:45] Florence: I think before we get into cancer vaccines specifically, it might be good to start with the basics. So vaccines are something most of us have heard of and probably experienced as well, but we don't always necessarily understand how they work. So Lennard, can I come to you to explain what a vaccine actually is, how it works with our immune system, maybe at the most basic level for those who might not have a scientific background?  [00:01:19] Lennard: Thanks, Florence. What's a vaccine? Very, very simply, something that protects your body from disease. We've had a few when we were younger, like which protects you against meningitis or hepatitis or different types of infections that can affect children.  [00:01:36] Lennard: And it really does show that your immune system is really powerful. Every day, it looks around trying to work out what's there which shouldn't be there and takes care of it. And ideally, your immune system just works in the background without causing any problems. And so what a vaccine does is it really helps the body understand something that's abnormal.  [00:01:55] Lennard: And the vision here is that you can use this technology to hopefully patrol against cancer, because half the people out there will never get cancer. They are the maybe the lucky ones or maybe the ones with a good immune response. And so a vaccine is basically giving your immune system a wanted poster:  [00:02:11] Lennard: "This is what threat looks like. This is what you need to control".   [00:02:16] Florence: And I think you mentioned some great examples there. There are lots of common examples of vaccines people might have heard of. I think maybe the flu vaccine is probably a common one that people are thinking about in the wintertime. I think another one is maybe the HPV vaccine.  [00:02:29] Florence: Lennard, could you explain a bit more to our listeners about the HPV vaccine? What it is, how it works? I think people often think of it as a type of cancer vaccine, but actually it's targeting a virus. Is that right?   [00:02:41] Lennard: Yeah, that's correct. So this is now a vaccine which has been rolled out across the NHS, and it's actually worked really well to get rid of a few cancer types, which is incredible.  [00:02:51] Lennard: And why is that important? Well, cancer can be caused by many, many different things. Sometimes it's because you've done things like smoking or weight plays a role or just bad luck or the genes that you've inherited. But some cancer types are caused by viruses. And so many people nowadays are getting the HPV vaccine to stop cancer types like cervical cancer, hopefully head and neck cancer, and many of the rarer cancer types.  [00:03:21] Lennard: And so again, what you're doing here is you're taking the immune response, telling it the body shouldn't get this virus and hopefully prevent some of the bad consequence of getting this viral infection, like cancers.   [00:03:33] Florence: Thank you. That's really helpful to understand. So we've talked about how vaccines can be used to treat viruses, and I think most of us, when we hear the word ‘vaccine', we probably do associate it with something that stops us from getting ill.  [00:03:46] Florence: Victoria, could you tell us about how vaccines could be used to treat cancer?   [00:03:50] Victoria: Yeah, absolutely, and it is great to be here today. Thank you. So Lennard's already sort of spoken about preventative vaccines, and when we think about cancer vaccines, we're thinking about therapeutic vaccines. So we're thinking about training the immune system to recognise the cancer as something that needs to be dealt with because cancer is really tricky because it's our own cells that have gone wrong, if you like.  [00:04:16] Victoria: But that means it also is very good at evading those signals which tell the immune system that it needs to be cleared. So the analogy that Lennard has already given of a cancer vaccine sort of creating a wanted poster sort of builds on an analogy from one of your previous podcasts where they described the immune system as like the police almost trying to catch criminals, which are the cancer cells.  [00:04:41] Victoria: And the cancer vaccine analogy builds on that. So you've created a wanted poster which is training and giving the police more information about what those cancer cells look like. And then when we think about building on that with sort of personalised cancer vaccines, which is an incredibly exciting step when we think about the development of how cancer vaccines can be used, sort of really individualised therapy going forward, that wanted poster gets even more specific.  [00:05:07] Victoria: It's almost like giving a phone number or an address for that specific cancer type that is very specific to that patient. So the therapeutic vaccine is, is targeting the immune system. It's training our immune system to recognise the cancer as something that needs to be dealt with.   [00:05:26] Florence: It's funny you mentioned that analogy because I was just about to point listeners to that episode. If anyone wants to learn more about cancer vaccines specifically, you can check out our previous Genomics 101 podcast episode called ‘What Are Cancer Vaccines?' So Ali, I think I'd love to bring you in at this point because you have experienced this from the patient side of things.  [00:05:49] Florence: Could you tell us a little bit about your journey, your cancer diagnosis and treatment, and maybe more about the clinical trial you were part of, if you feel comfortable sharing that?   [00:05:57] Ali: Yeah, sure. Hi, Florence. It was Christmas 2015, and I felt a lump in my neck. And maybe because I'm a woman and we're always taught to treat lumps seriously, in the January I made an appointment with the GP, and she very quickly fast-tracked me through to the hospital.  [00:06:19] Ali: And January 2016, I got a diagnosis. It was a tumour on the base of my tongue at the left, and I was told it was caused by a variation of the HPV virus. So yeah, that was all a bit of a shock. I was shocked and I was scared, but I was also really angry because I look after myself. I eat well, all those things.  [00:06:45] Ali: It's just bad luck that it was a virus that my body couldn't deal with. I just, I felt guilty as well because of what I was gonna put the family through. So I had various scans and tests. I had an operation to remove my tonsils, although we soon discovered there weren't any left anyway. And they took a biopsy, which I didn't know at the time, but turned out to be important later on for the trial.  [00:07:15] Ali: Then I had to have a whole load of prep beforehand because of the impact of the treatment. So I had to have restorative dentistry, audiology tests. I had a PEG fitted, that's a feeding tube, in my stomach, and I thought, "Surely it's not going to be this bad." But that PEG, that feeding tube was a blessing in the end.  [00:07:40] Ali: And I had a mask made, and the mask fits you and basically pins you down to the radiotherapy table so you don't move when... because it's very precisely targeted at your tumour. So yeah, I went on to have five sessions of chemo, which felt quite easy. The radiotherapy was the really, really tough part. I had, uh, seven weeks of it, 35 sessions.  [00:08:08] Ali: So that was, yeah, that was a challenge.   [00:08:11] Florence: Thank you, Ali. Thank you for sharing that. I think it's always really valuable to get that patient perspective when we're talking about things like this. Lennard, I wanted to come back to you now to talk about the different types of vaccines that exist and which ones are being used specifically in the treatment of cancer.  [00:08:30] Lennard: Um, thanks, Florence. And Ali, are you 10 years now down the line since your diagnosis?   [00:08:34] Ali: Yeah, it feels good.   [00:08:37] Lennard: Congratulations.   [00:08:38] Ali: Yeah, yeah. It feels good. I really valued the follow-up checks that I had, both from my oncologist, but also I got some through the trial, and it really helped restore some confidence in myself and my body to deal with things and to be able to move on as well.  [00:08:56] Lennard: Oh, well done. That's fantastic because you telling us that story just really brings it to life about how scary this can be and also the fact that you had to go through all those sessions, thirty-five sessions and, um, and now you're 10 years down the line and still talking and giving hope-   [00:09:11] Ali: Yeah ...   [00:09:11] Lennard: that new technology still comes, so thanks, Ali.  [00:09:13] Ali: That's a pleasure.   [00:09:14] Lennard: Um, yeah, so Frances, this is what's really exciting. What types of vaccines are there? Well, first thing to say is that we're really good in this country about vaccine research. If you look around the world, what are we good at? Well, everyone knows that we developed the pandemic vaccine, and actually that technology is something that we can control.  [00:09:31] Lennard: We're world leaders at. It's quite cheap technology, and it's something that we are really good at bringing to patients. And Ali's our testament where she got on the trial, she helped test it and really pioneered new ways of research. So what types of vaccines are there? Well, I think we talked to the first bit where Victoria taught us that some of them can treat cancers and some of them can maybe prevent cancers.  [00:09:53] Lennard: And the HPV's one which is maybe be able to do both one day, which is brilliant. What would like... what else do people know about? Well, people might know that there are different types of technologies. So if we think back a few years now, back to 2020, there are some which are viral-based, and some which are mRNA based.  [00:10:12] Lennard: Both of these were new technologies which the whole population of the world came together to create and some of them are peptide-based. So there's probably three different types here. The protein ones or peptide one, which you always had, and then in the last five years, it's an incredible time to be alive, where new vaccine technology comes through, it's more effective and safer.  [00:10:32] Lennard: These are the viral ones and mRNA ones, and everyone's now pursuing all of these to try and make sure that we can maybe treat cancer in future.   [00:10:41] Florence: Can I possibly pick your brain a little bit more about the mRNA ones specifically? I think as you mentioned, lots of people might have heard of those during COVID.  [00:10:50] Florence: Could you maybe explain a little bit more about those and how they work?   [00:10:53] Lennard: Yeah. So this is going to take us all the way back to GCE biology now. If you remember - and we are Genomics England, so we, we got to work out why genomics is important, and we'll probably get to this. But remember, genes make RNA, which then makes protein.  [00:11:11] Lennard: And so if you're trying to reprogramme the immune response, you could give your body a protein, the back end of it. You can maybe give it an RNA, which is a blueprint too. And so what an mRNA vaccine is, it's a way of giving the blueprint or the instructions to the body of what to recognise, what the cancer looks like, um, um, or what the virus looks like, and target it.  [00:11:32] Lennard: If you want the analogy, well, for those people who had the pandemic vaccines, the ones which was mRNA based was, uh, the Pfizer one, and that worked really, really well. Cheap to make, easy to produce, and, uh, it's just a jab. And so people are now exploring that for cancer treatment now. Take new technology, which has only been developed five years ago, technology, which is just a blueprint, cheap to make, easy to update, and now we're targeting cancer.  [00:11:59] Lennard: Um, so that's basically what an mRNA vaccine is, giving the body the blueprint or the instruction of what a cancer looks like and trying to target that cancer.   [00:12:08] Florence: And you kind of alluded to it a little bit in your answer, but, um, it would be good to know more about where genomics comes into all of this. You know, why is it such an important part of developing vaccines?  [00:12:18] Lennard: And that's a great question, and really comes back to our second strengths, which is that we're really good at vaccine research, and yet we are also world leaders at genomic research. It's a really exciting time because, um, when Victoria and me and Ally at school, we would-- we, we learnt about that race to sequence the first human genome.  [00:12:38] Lennard: It was really exciting because for the first time, we can see every single genetic base in every human, and that used to cost billions of pounds to do that, and it would take many months or years to do that Fast-forward a few years, and then now Genomics England delivered the next success for humanity.  [00:12:57] Lennard: I think it was about 2015 to 2017 where they, they did 100,000 Genome Project, where the UK led the world in sequencing 100,000 people, including people with cancer, to try and understand what caused their cancer, what the risk factors are. And why is that relevant now? Well, it's because if you know what a cancer looks like, then you know what the abnormality is, well, then you can vaccinate against it.  [00:13:22] Lennard: So we've now gone from this amazing arc of discovery here, where when we were at school, we worked out what the human genome looks like. We can sequence it end to end and see in all its detail. Then a, an amazing organisation came out the ground called Genomic England, which shows that you can run it in the NHS.  [00:13:39] Lennard: 100,000 people could do it. And now we're making the next big jump now, which is it's not just going to give you a diagnosis, but maybe becomes a drug and a vaccine in future. And actually, probably it already has because Ali's that example, a success example of it happening.   [00:13:54] Florence: Yeah, I wanted to actually ask you about that, Ali.  [00:13:56] Florence: So just as you were saying, Lennard, it kind of... The cancer vaccine sounds quite futuristic, but as you said, it's, it's sort of already happening. So Ali, do you remember kind of how you first heard about the cancer vaccine trial?   [00:14:11] Ali: Yeah. I had a bit of an unfortunate time because after all that radio and chemo, my cancer still hadn't gone, and I had to have an operation to remove lymph nodes.  [00:14:22] Ali: But my oncologist at Poole Hospital, who's a fantastic woman, she had been involved, unknown to me, in the some of the thinking behind the trial, and particularly that she could recruit people because they were sat in her office. So she asked me if I'd like to take part, and without knowing anything, I said yes.  [00:14:49] Ali: And the reason I said yes was because my treatment really was punishing. It was so many side effects to it. The cancer never made me feel sick, but the treatment made me really sick. So I said yes because I just wanted to help other people not have to go through what I went through. I didn't really understand it, if I'm perfectly honest.  [00:15:16] Ali: I didn't really know what was going on, but then I'm not, you know, a super brain like Lennard and Victoria. I knew that I just wanted to do something to help people going forward, not having to deal with the same. So yeah, I put my hand up and there I was on the trial.   [00:15:37] Florence: So you mentioned there the, the really horrible side effects that you got from your original treatment. Did you have, um, what was your experience with side effects with the vaccine? Was it similar? Was it different?   [00:15:47] Ali: Oh, no, the, the vaccine was like a holiday compared to the treatment. Absolutely. At, at worst, in the first few treatments, you felt a bit like you had a cold, bad cold coming on, maybe slightly flu-y, but you took, you were given Ibuprofen at the same time as you had the vaccine.  [00:16:10] Ali: So no, it, the treatment with the vaccine was an absolute breeze. Which is kind of like, yes, this is what I want for people. You know, not, not the radiotherapy, not the chemo. So yeah, it was, it was really very easy by comparison.   [00:16:29] Florence: Oh, I'm so glad to hear that that was your experience. I'm just curious now also, was there anything that surprised you about the trial?  [00:16:35] Florence: You said there that you didn't really, like, have an understanding of cancer vaccines. You, you agreed to it straight away. Was there anything that maybe, like, you weren't expecting or surprised you?   [00:16:45] Ali: I think it surprised me that it was really quite easy.   [00:16:48] Florence: Yeah.   [00:16:49] Ali: Uh, I was delighted to have the team I had looking after me because they were fantastic. It all felt very simple.  [00:16:59] Ali: And how nice that was. You know, if I could've had that instead of all my previous treatments, um, it would've, it would've made everyone's life so much easier. And I guess, I don't know about the cost of drugs, but I guess the cost to the NHS would've been less because I wasn't in and out of hospital, I wasn't having to have all these extra things done, and all this extra support like dieticians and so on because I had to have my feed tube replaced.  [00:17:35] Ali: So all of that is impacts on the NHS, whereas this was very simple.   [00:17:40] Florence: I wanted to come to you now, Victoria, and ask you about the outcomes of this trial that Ali took part in or other trials like it, and whether we know yet what the broader implications of, of these advances might be.   [00:17:55] Victoria: So I think what we need to think about when we're thinking about developing these treatments and sort of evaluating the treatments at each stage is that it goes through a very clear pathway of progression, and Ali was involved in one of the, the earliest stages of that progression.  [00:18:09] Victoria: And it's, it's always amazing to me to hear your story, Ali, and to know that patients are willing to take part in the research and that's what allows us to develop these treatments. So the trial that Ali was part of has now gone on to develop into a, a larger scale study which will be evaluated again.  [00:18:27] Victoria: And that all starts to form the evidence for how these treatments can be shown to be effective, and also how they can show... Also, you know, Ali's already touched on there about the cost implications, so how we can show that that can be beneficial as well. And then we can start to think about how they can be taken up and become part of routine standard of care for patients like Ali, as she was describing.  [00:18:50] Victoria: And all of that evidence comes together, which then gets evaluated and then it, and then it moves forward through that progression. But it's-- we have very clear, um, you know, a, a route that each new, new treatment has to go through, um, to be able to, to become part of standard of care.   [00:19:07] Florence: And Victoria, you also play a key role in the Cancer Vaccine Launchpad.  [00:19:12] Florence: For any listeners who might not be familiar with the Cancer Vaccine Launchpad, could you maybe tell us a little bit more about it?   [00:19:18] Victoria: Absolutely. So in its simplest terms, the Cancer Vaccine Launchpad is designed to help find patients who might be eligible to take part in trials like the one that Ali was part of.  [00:19:30] Victoria: It's an incredible project. Cancer Vaccine Launchpad is quite long, so we tend to abbreviate it to the CVLP, which I'll do from now on, if that's okay. The CVLP to me really demonstrates the power of collaboration because it's brought together so many different teams that have been necessary to make sure that, that what we're trying to achieve, so finding as many patients as possible for these trials, is possible.  [00:19:52] Victoria: We deliver this project on behalf of NHS England. I know that Lennard was involved right from the start as well. The reason that we need the CVLP is because one of the biggest challenges in research of these new treatments is finding the patients who might be eligible. So one of the reasons for that is because when we are running the trials to test these new treatments, there's a lot of different infrastructure that's needed to support the delivery of those trials.  [00:20:19] Victoria: So you need special pharmacy services, special research nurses. All of that has to come together to be able to deliver trials of new treatments. And actually, that means that actually those studies can often only take part in a small number of hospitals. So historically, you only had the opportunity to take part in those trials if you lived near one of those hospitals, which is, you know, like Ali did.  [00:20:42] Victoria: So what the CVLP is, what, what it has done, it has created a formalised network which enables referrals to happen from ... we're opening 83 hospitals now across England. We've just expanded out to the devolved nations as well, which is a really exciting development, and it creates that, that network which allows patients who might live further away from a hospital delivering one of those vaccine or immunology trials to be able to be referred in to see if they might be eligible.  [00:21:09] Victoria: So essentially, it's a bit like creating a big funnel. So you're finding all of the potentially eligible people that could take part in that trial, and you're funnelling them into the trial site to find those patients who are eligible.   [00:21:22] Florence: And what impact do you hope that this could have for the NHS and also for, like, individual patients as well?  [00:21:29] Victoria: So we've seen such positive results from the CVLP so far. The first study that we worked with was for a colorectal cancer vaccine trial. Before the CVLP started working with this trial, only 17% of the eligible patient population in England had the opportunity to take part because they lived near one of those hospitals delivering the trial.  [00:21:52] Victoria: After the CVLP started working with it, we had increased that to over 60% of the eligible patient population. So you could really see how it has expanded out access, and that's just a fantastic opportunity to be able to bring, to bring patients. We also were able to show that the UK was screening, so looking for patients at three times the global average.  [00:22:14] Victoria: So we really were able to see how the CVLP is supporting and accelerating recruitment to those trials I think the key thing for me has been the patient enthusiasm that we have seen though. So when we open up to a new trial where, that the CVRP is working with, we are always inundated with people who contact us to find out how they can be part of this network because they want the opportunity to take part.  [00:22:40] Victoria: We know that some patients have travelled for two hours to a trial site to find out if they could be eligible because actually they want the opportunity. So the CVRP has really sort of enabled that patient choice, which is a fantastic thing to be able to do. But it also builds on what Lennard was talking about earlier, which is the UK is really good at this research and actually what the CVRP is then doing is showing how we can really support recruitment to these trials to accelerate these trials and that only brings more trials to the UK which again creates more opportunities for patients which is exactly what we're trying to do.  [00:23:14] Victoria: We're trying to create more and more opportunities for patients to take part in these studies if they want to.   [00:23:20] Florence: Yeah. That's really incredible. Thank you for sharing that with us. I wanted to ask you a question now, Ali, because I think when we were talking about trials and projects like this, as Victoria said, we often think about kind of the high level impact, but also it's an opportunity to create connections as well between patients and families and, and I know that you, you had a patient's family reach out to you about advice as to-- about whether they should take part in a trial. Is that right?   [00:23:47] Ali: Yeah. I think it was the wife of a guy up in Liverpool who had throat cancer, and, um, she must have done some really good research on the internet. I'd done various bits of publicity both for Southampton Uni and cancer research around the trial. So she obviously found me and then stalked me on Facebook , which was absolutely fine.  [00:24:13] Ali: I didn't have a problem. So her husband was down to go on the trial, which is the next stage that Victoria had spoken about, and she just wanted to know, would I recommend it, would-- what was it like, that kind of thing. So I said to her, "I would absolutely recommend it, of course," and told her what my experience was.  [00:24:35] Ali: I couldn't guarantee his would be the same, of course, because things might have moved on. But it was a really, it was a kind of a nice feeling that I could say to her, "Get him to have it done because it's got to be the best outcome." I think his stage was much further on than me. So yeah, it had to be the way as far as I could see for him. And as far as I know, he went on the trial. Which is great.   [00:25:05] Florence: How, how did it feel to kind of make that human connection, maybe not something you were expecting to come out of a trial?   [00:25:13] Ali: No, it was really, it was really nice. I am a bit of a, a fangirl for, for Lennard and Victoria and all the team at Southampton.  [00:25:22] Ali: If anybody asks me about vaccines and cancer vaccines, I'm like, "Oh, yes." And you-- So yeah, I'm, I'm a bit of an evangelist. So to, to have somebody real-   [00:25:33] Florence: Mm ...   [00:25:34] Ali: ask me about that was great feeling.   [00:25:37] Florence: I think that's a, a really great example of how research can have impact far beyond, uh, one individual. And I think another great example of this is also artificial intelligence or AI as a potentially transformative force in, in healthcare.  [00:25:54] Florence: Lennard, when we come onto this topic, I wanted to hand over to you because I know that you've recently received funding for a project exploring AI, and how it could support cancer vaccine development in particular. Could you tell us a bit more about this project?   [00:26:08] Lennard: Thanks very much, Florence. And I also want to add, I feel very proud about what Ali did just there, where she's able to bring through opportunity for other people, too, which is amazing.  [00:26:19] Lennard: The NHS is there to not just do the technology of today, but also be one of the best healthcare systems in the world to bring through new technologies. And it's just really exciting about people wanting to help the NHS, advocating for new technologies to be tested, and actually that's what Genomics England i there to do, make sure the NHS gets new technology in there so that patients will get new treatments.  [00:26:41] Lennard: I just wanna just reflect what Victoria noted In the NHS, in their Cancer Vaccine Launchpad, patients are getting in at three times the rate of other countries.   [00:26:51] Ali: Mm-hmm.   [00:26:52] Lennard: That's really special. And also she's increased coverage to, uh, did you say 60% of population? That's 42 million people have potential access to this.  [00:27:01] Lennard: So that is huge, and I think it's really a passion project for so many people out there, PICT trials units, the research nurses and doctors, and also patients who make this all happen. So it is quite impressive. It is very impressive. Oh, yes, and AI. I probably should cover that too. Just beyond what's special about the NHS and Genomics England.  [00:27:22] Lennard: Well, AI I think is changing everything. I went to a garden party, and actually everyone's talking about how they're using AI to make their lives simpler, make them do things that they've never been able to do before, get the information instantaneously there. And I think that there's technologies which come through every so often in our lifetimes, which changes how we think, how we communicate, and actually makes us better in many ways.  [00:27:47] Lennard: And so the great opportunity here is what happens if we take that third strength now? So we've already said we're really good at vaccine research in the UK. The UK invented vaccines. We also are world leaders at genomics. We did the 100,000 Genome Project. What happens if we use this new technology now?  [00:28:06] Lennard: And what's a problem that we can solve? Well, let's say we did a whole genome sequence on someone, which is what Genomics England does every day for the NHS. Well, that creates a lot of data. Um, I tried to do the calculations before we went online. It's about 100,000 photos. You know, when you take on your phone, that's a lot of data.  [00:28:25] Florence: Wow. Yeah.   [00:28:26] Lennard: And that's a miracle what's happening in the NHS and Genomic England, and we need to make a cancer vaccine out of that. And so you need to process that. So that's time-consuming. It could be automated. And so what AI could do now in future is that we could use the supercomputer we built in the UK.  [00:28:43] Lennard: In fact, we are doing this already. We've built supercomputers in the UK, and we're going well beyond other tools out there and designing cancer vaccines. And the AI scientists which can do that can do it at weekends, at nights, and help design the drugs. And so what it does is it heralds a future where every patient can contribute into a model that's created in the UK, stored safely in our supercomputers.  [00:29:07] Lennard: It can now be made into drugs, and the UK will start to make things again, which will hopefully change cancer care across the world. We can deliver that legacy whereby our three strongest strengths come together - vaccines, AI, and genomics. It then super powers the NHS and everything that Victoria's done in the Cancer Vaccine Launchpad, so many millions of people around the world can get access to trials.  [00:29:31] Lennard: And people like Ali can also help hold up the NHS even further. So people once again look back to us and say, "If you want to get things done, come to the NHS because it provides world-class care for patients." And so that's a big initiative now. Use AI to make better drugs, safer drugs, more effective, more precise in the UK. And it's only possible because of everything that we've built here with our funders, ARIA, MRC, Cancer Research UK, people raising, raising money through cake bake sales to make this happen.  [00:30:02] Lennard: So it's very exciting.   [00:30:04] Florence: Yeah. I think AI can be a topic that people often have very strong opinions about. When it comes to AI in, in your line of work, are there any misconceptions you think people might have, or are there any benefits to using it that maybe people might not be aware of?   [00:30:21] Lennard: Oh, that's a tricky question, isn't it? I think you're right. Any tool that comes through can be used for good things and, and things that people will question because maybe we don't want to cross those boundaries. And yet I think what we're doing here is really special because we want to - as long as your heart's in the right place - we want to give more people like Ali hope so that she knows that one day the drugs in the NHS will be much safer so you don't get all those side effects, much more effective, much more precise.  [00:30:52] Lennard: And on top of that, people like Victoria will be able to bring even more trials in the UK which will change lives and change practices around the world through an amazing working launchpad. So I think that's the right use of AI, make people's lives better. I think there are other uses of AI which I probably scratch my head and say, "Well, should we be doing that?"  [00:31:10] Lennard: And that's what I think it's really special that we do think about these and talk about these things here, and then bring the public with us because I know that people reach out, and Ali's been reached out in the past before, and I think we need to have this discussion here. Is AI right to develop cancer drugs using capabilities from Genomic England to go through the NHS Cancer Vaccine Launchpad?  [00:31:31] Lennard: I say cautiously, yes, and we should do more of this. And I think the most important thing is there's a lot of people starting to use AI for benefit, and you know my views, Ali, and I don't know if they're right. Um, I'll be a bit cautious, but I do want to ask you, Ali, is this the right use of AI? Should this be what we develop?  [00:31:50] Lennard: I don't know what you're going to say.   [00:31:52] Ali: For me, I think it is. I do think AI is a bit if you put rubbish in, you get rubbish out. But if you- If you ask the right questions, if you give it data analysis and experts like you have set up the protocol in the first place and it makes everything faster and reliable, then it's got to be the right thing.  [00:32:16] Ali: It gets used and abused for things, that isn't what AI should be doing, in my opinion. It should be used to do-- to help us, to supplement the work that we're doing, uh, and make it even faster than you're already making it.  [00:32:38] Florence: Well, we've covered so much today from how vaccines work to the role of genomics, NHS trials, and of course, what all of this could lead to. So before we wrap up, I have two final questions for each of you. What do you think is the most important thing for listeners to understand and take away from personalised cancer vaccines?  [00:33:01] Florence: And what are your hopes for the future? I think we'll start with you, Victoria, if that's all right.   [00:33:08] Victoria: Yeah, absolutely. It's been a great conversation. Uh, there's so much to think about. I think when I think about what I'd like listeners to take away, I think it's that cancer vaccines, and particularly personalised cancer vaccines, really support and represent this paradigm shift that we're seeing towards a much more personalised, uh, treatment pathway.  [00:33:27] Victoria: You know, like we've described, generating a cancer vaccine that has come from the patient's tumour, so the, the, the vaccine is, is designed to recognise mutations that are specific to that patient. It is such an incredible thing to be sort of witnessing and to see how that's developing through into sort of really changing patient care, and that's, you know, we've spoken about this so much, but that's been due to such incredible collaboration across scientific disciplines, across the NHS, pathologists.  [00:33:58] Victoria: Everyone has come together to make all of this possible, and that's, that's an amazing thing to be a part of. In terms of my hopes for the future, well, I would like the Cancer Vaccine Launchpad to be open in every hospital across the UK to really sort of underpin that acceleration and to provide that opportunity for patients.  [00:34:17] Victoria: You know, I'd just like to give a, a final shout-out to everybody who has been part of the Cancer Vaccine Launchpad from its very start, who's enabled this to happen and, you know, it's just been fantastic to see how this has, you know, supported patient choice for trials. And I guess if there's one tiny other thing, perhaps we could see how this, you know, this, what we've put together could be applied to other disease areas as well.  [00:34:39] Victoria: But yeah, that, that would be my hope for the future, is it's open everywhere one day.   [00:34:43] Florence: And Ali, I'll come over to you next.   [00:34:45] Ali: I think what I'd say to any patient that was asked to go on a trial is, is just go for it.  [00:35:02] Ali: And you know, Victoria, Lennard, all the rest of the team, you know, you are not doing jobs. You're leaving a legacy in my view. That's such an important thing. So yeah, if you're offered a trial, get on it. And my hope for the future is that everybody can have kinder, gentler treatments. The radiologists and chemo nurses I came across were lovely, lovely people.  [00:35:31] Ali: But yes, I'd like to see them out of work and doing other things within the NHS because they don't need to do that work anymore. That, that's my dream.   [00:35:40] Florence: Mm. And Lennard, any, any final thoughts?   [00:35:44] Lennard: Thanks, Ali. I mean, your words gave me goosebumps about the amazing stuff that the whole community's doing for cancer vaccines, AI and genomic research.  [00:35:51] Lennard: It's so powerful. Um, okay. What's the final thing? I think it's hope. Look, the country's in a new place now. You've got brilliant scientists running clinical trials, like the Cancer Vaccine Launchpad, which is reaching out to every single hospital. You've got patients who are building up the NHS again to deliver future care, and scientists using AI and genomics to make cancer vaccines.  [00:36:11] Lennard: That is a good reason to be hopeful. When lots of things are going in other places of the world, great things are happening in the UK.   [00:36:20] Florence: This has been such a brilliant conversation.  [00:36:25] Florence: A huge, huge thank you to our guests today, Dr. Victoria Goss, Professor Lennard Lee, and Ali Richards, for joining me in our brilliant discussion about cancer vaccines.   [00:36:50] Victoria: Thank you so much for having me.  [00:36:55] Ali: Thank you, as always. I've learnt a lot.   [00:37:00] Lennard: Thank you very much, Florence, too, from me.   [00:37:10] Florence: If listeners have enjoyed this episode and you'd like to hear more, please subscribe to Behind the Genes on your favourite podcast app.  [00:37:16] Florence: I've been your host, Florence Cornish, and Behind the Genes is produced by Deanna Barac, Sharon Jones, Sophie McLachlan, and Patrick Wallace at Bespoken Media. Thank you for listening.   

  Are you doing everything "right" for your health and still not getting the results you expected? In this episode of the Sisterhood of S.W.E.A.T., Linda Mitchell sits down with Kim Ressler, Founder and CEO of SNiP Nutrigenomics, to explore the growing world of DNA-personalized nutrition. Kim shares how her own search for answers led her away from one-size-fits-all wellness protocols and toward understanding her individual genetic blueprint. Linda and Kim discuss how genetics may influence nutrition and supplementation, the difference between what bloodwork and DNA can tell us, why genes are not necessarily destiny, and how women can stop chasing every new diet, supplement, wearable, and biohacking trend. They also explore what personalized nutrition could mean for women navigating midlife, changing hormones, performance, and longevity. In this episode, you'll learn: • Why one-size-fits-all wellness can fall short • What nutrigenomics actually means • What DNA can and cannot tell you about nutrition • The difference between genetic information and bloodwork • How genetics may help personalize supplementation • Why genetic predisposition does not automatically equal destiny • The potential role of DNA in women's health and longevity • Why expensive biohacks shouldn't replace foundational health habits • How SNiP Nutrigenomics is working to make personalized nutrition more accessible Connect with Kim Ressler: SNiP Nutrigenomics snipnutrition.com Use Discount Code SOS 50 for $50 off  Summary In this episode, Kim Russler, founder and CEO of SNP Neutrogenomics, shares how personalized genetic insights can revolutionize nutrition and wellness. Discover how understanding your DNA can help tailor your diet, supplements, and lifestyle for optimal health and longevity.  Key  Topics The role of genetics in personalized nutrition How DNA testing can identify nutrient needs and deficiencies The impact of genetic markers on health conditions like autoimmune and inflammation The importance of foundational health and targeted support Future trends in precision medicine and wellness  Takeaways Understanding your genetics can help tailor your diet and supplements more effectively. DNA testing can reveal specific pathways like methylation and detox that impact health. Personalized nutrition supports better immune function and longevity. Genetics can explain why certain diets or supplements work for some but not others. Supporting genetic pathways with targeted nutrients can improve overall well-being.  Sound Bites "Folic acid impacts inflammation and detox pathways" "Genes work like a symphony, supporting each other" "Stop guesswork, support your body in a personalized way" Chapters 00:00 Introduction to Kim Russler and SNP Neutrogenomics 01:56 Kim's personal health journey and discovery of genetic testing 05:05 Understanding the role of genetics in nutrition and health 08:52 How genetic markers influence supplement needs and diet 13:04 The importance of foundational health and lifestyle choices 16:57 Genetics and aging: menopause, hormones, and longevity 21:11 How SNP Neutrogenomics personalizes health support 24:59 The future of personalized medicine and wellness 29:06 Kim's vision for accessible genetic health solutions 32:52 Final thoughts: empowerment through genetic understanding

Dr Bruce Lipton will tell you that the most dangerous idea in modern health is also the most widely believed one. That your genes control your life. He is a world-renowned stem cell biologist, former medical school professor, bestselling author of The Biology of Belief and now Beyond Darwin, and one of the pioneering voices of the science of epigenetics. His fascination began in second grade, the first time he looked through a microscope and watched amoebas moving with what he swears was intention. Years later, growing cells in a petri dish as a research scientist, those cells taught him something that contradicted the very curriculum he was teaching. Genes do not control life. So when Catherine opened the conversation, Bruce did not ease into it. There is no gene, he says, that causes cancer. The victim programme Bruce’s argument starts with what the standard story does to us. If genes turn themselves on and off, and you did not choose your genes, then your health is out of your hands. That belief, he says, programmes people into victimhood, and victims hand their power to someone else. He points to the research he finds most telling: children adopted into families where cancer runs through the generations go on to develop the same family cancer, despite carrying completely different genetics. What travels down a family line, Bruce argues, is not a faulty gene. It is programming, beliefs, identity and ways of living passed from parent to child. What stress actually does to your body The mechanism at the centre of it all is stress. Bruce walks through it with the relish of a man who has explained it a thousand times and still finds it astonishing. Stress hormones squeeze shut the blood vessels of the gut, halting the maintenance and repair of the body. They shut down the immune system to conserve energy. And they push blood from the conscious forebrain to the reactive hindbrain, so we literally become less intelligent under pressure. That response was designed for fifteen minutes of running from a sabre-toothed tiger. Today it runs 24 hours a day, and Bruce’s number is stark: over 90 per cent of illness on this planet traces back to stress, while less than 1 per cent of disease is meaningfully connected to genes. The architect above the blueprint This is where epigenetics comes in, and Bruce’s metaphor makes it land. Genes are blueprints, and blueprints cannot build anything on their own. They need an architect. The architect, he says, is the mind. Epi means above, so epigenetics literally means control above the genes. If your consciousness is in harmony with the world, your biology follows. If your consciousness is in conflict, your biology becomes the battlefield, which is why so much modern illness is autoimmune, the body quite literally attacking itself. You are not the TV, you are the broadcast The most memorable stretch of the conversation is Bruce’s answer to the question of who we actually are. Every cell in your body carries a unique set of self-receptors, antennas found on no other human being alive. What are they receiving? An energy field. In physics, an invisible moving force that influences the physical world. In every spiritual tradition, that same definition has a shorter name: spirit. Your body, Bruce says, is a television set playing your broadcast. When the TV breaks, the broadcast does not disappear. It is the TVs that come and go. The programmes running your life Bruce’s most practical point is also his most confronting. In the first seven years of life, a child’s brain downloads its environment without filtering it, and criticism heard in those years becomes programming: not good enough, not lovable, not safe. Two beliefs, he says, fail in 80 to 90 per cent of people when tested: I love myself, and I am safe. And because 95 per cent of daily life runs from subconscious programmes rather than conscious wishes, learning new facts changes nothing on its own. You have to rewrite the programme. Bruce speaks from experience. For his first 40 years, he ran his father’s downloaded behaviour through every relationship he had, until he recognised the programme, rewrote it, and has spent the 30 years since, in his words, living heaven on earth, honeymoon every day. Bruce leaves the audience with a simple charge. Do not wait to die to experience heaven. We were born into it, and we manifest it, or its opposite, through the consciousness we bring. Change the programme, and you change the life. Watch the full conversation on YouTube. Get Bruce’s new book, Beyond Darwin: https://www.simonandschuster.com/books/Beyond-Darwin/Bruce-H-Lipton/9781637749364 Find Out More About Dr Bruce Lipton Website: https://www.brucelipton.com (free articles and subconscious reprogramming resources) Instagram: @brucelipton Facebook: Bruce H. Lipton, PhD

Today's In Focus brings you the story of a German count, his castle, and the dollar in your pocket as part of the series "Genealogy in your Genes."

Have you heard about the radioactive wolves in Chernobyl? Or the latest gene-editing tech that's curing rare diseases? Or that male birth control might be on the horizon? No?!Well, get ready, because while we've been busy living our lives, genomics has been moving – fast! Things that once read like science fiction are moving on over to the non-fiction section.This season on Nice Genes!, join Dr. Kaylee Byers as she engages in some big genomics breakthroughs – from personalized cancer treatments, to how our bodies react in space, to how animals adapt to the most extreme environments, and whether we can actually change how we age.It's a whole new gene-eration (if you will) of discoveries that you won't want to miss!New episodes every two weeks, starting September 8th. Make sure you follow Nice Genes! so you don't miss an episode!

Let's talk about how much of our health is actually determined by our genetics?Access the Mindful Eating & Healthy Living Course here:https://yourlifenutrition.org/course/Schedule a FREE Discovery Call with me here:https://yourlifenutrition.org/nutrition-coaching-application/.Come join our private accountability group, the Goal Getters Group, for all things health, wellness & nutrition! You'll get sample weekly meal plans, recipes, weekly group coaching calls and access to our exclusive Blood Sugar, Wellness, Mindfulness & Movement Challenges to help support you and keep you accountable on your health & nutrition journey AND get access to private messaging with me, your dietitian!Click the link below to join the Goal Getters Group today!https://your-life-nutrition-goal-getters.mn.co/plans/1821314?bundle_token=1724009ab3ed355237fdeeebd2fe1d9f&utm_source=manual.For health & nutrition tips, recipes & more - follow me on:Instagram: https://www.instagram.com/yourlifenutrition/Facebook: https://www.facebook.com/yourlifenutritionrdn/Email: Brittany@yourlifenutrition.orgShop my Favorite Products!Stelo Continuous Glucose Monitor System**I am an Amazon Affiliate and may earn commissions on qualifying purchases.

At 64, Pam has lost 45 pounds without a GLP-1, but that is only one part of her transformation. For years, Pam knew something wasn't right. She was gaining weight, exhausted, frustrated, and tired of trying things that simply weren't working. She and her husband had reached a point where they were sick of feeling stuck and didn't know what else to do. But Pam's story began to change when the focus shifted away from yet another generic plan and toward understanding what was actually happening inside her body.In Part 1 of this special two-part series, Susan sits down with Pam and her sister, Leslie, to share the raw, real story behind their health transformations. They explore how genetics, labs, stress, metabolism, digestion, and lifestyle helped uncover pieces of their health that had previously been missed, including genetic lipid risks such as Lp(a) and phytosterolemia. In this episode the focus is on Pam. This conversation is about much more than a number on the scale. At 64, Pam has lost 45 pounds, feels dramatically better, and has changed the trajectory of her health by learning how to work with her individual biology. Her story is a powerful reminder that feeling better is possible at any age, and that sometimes the answer isn't trying harder, but finally understanding what your body needs.In This EpisodeWhy Pam felt exhausted, frustrated, and stuck after repeatedly trying to improve her healthHow personalized testing revealed genetic and metabolic factors that helped explain what was happeningWhat Pam learned about Lp(a), phytosterolemia (ABCG8 genes), stress, digestion, and their impact on her individual health risksWhy weight loss became a by-product of helping her body function better rather than the only goalThe lifestyle and nutrition changes that helped Pam lose 45 pounds at age 64Why feeling seen, heard, and understood can completely change someone's health journeyCome back next week for Part 2, where Pam's sister Leslie shares her own very different journey, from overwhelming fatigue, weight gain, hormone struggles, and years of trying to figure out her health on her own to finally understanding what her body needed. Two sisters, shared genetics, but two distinctly individual and impactful health stories that will inspire you.RESOURCES:Connect with Pam Fowler:https://galenoiabrainwellness.com/Find all of Susan's Resources and links in the show notes: https://healthyawakening.co/2026/08/24/episode137/Connect with Susan: https://healthyawakening.co/Visit the website: healthyawakening.co/podcastFind listening links here: https://healthyawakening.co/linksP.S. Want reminders about episodes? Sign up for our newsletter, you can find the link on our podcast page! https://healthyawakening.co/podcast

Bad Genes Month is still growing with another human / plant combo in the form of this early comic book movie adaptation of #DC's #SwampThing. This is directed by Wes Craven. We talk about the films strong opening, the surprise nudity for a PG film and that Swamp Thing costume.

What if your genes aren't controlling your destiny nearly as much as you've been taught to believe? And what if many of the patterns shaping your health, relationships, behavior, and perception of the world were programmed into you before you were even consciously aware of them? In this powerful conversation, Darin sits down with stem cell biologist and bestselling author Dr. Bruce Lipton to explore his theories around epigenetics, subconscious programming, consciousness, stress, evolution, and the mind-body connection. Bruce also opens up about his experience with tongue cancer and how it forced him to confront the very ideas about biology and belief that he had spent decades teaching. Together, they explore Bruce's claim that we spend as much as 95% of our lives operating through subconscious programs, many of which were downloaded during early childhood. Bruce explains why he believes our perception of the environment influences biology, why taking responsibility for unconscious patterns is essential to reclaiming personal power, and how those programs can be rewritten. The conversation expands beyond individual health into humanity itself, challenging the cultural story of "survival of the fittest" and exploring cooperation, community, consciousness, spirituality, environmental collapse, and why Bruce believes the upheaval we're experiencing may actually represent an evolutionary turning point. What You'll Learn How Bruce's experience with tongue cancer challenged him to apply his own teachings Why Bruce believes subconscious programming controls much of our everyday behavior How childhood experiences may become unconscious programs that follow us into adulthood Why falling in love can temporarily interrupt subconscious programming Bruce's explanation of epigenetics and why he rejects genetic determinism Why taking responsibility for your unconscious patterns can help you reclaim your power How stress, belief, and perception interact within Bruce's model of health and disease Why Bruce challenges the cultural interpretation of "survival of the fittest" How cooperation, community, and harmony fit into his theory of human evolution Why Bruce believes changing collective consciousness begins with individuals living differently Chapters 00:00:03 – Welcome to SuperLife 00:00:34 – Sponsor: Miko Dog 00:02:00 – Introducing Dr. Bruce Lipton 00:03:33 – Bruce's personal experience with tongue cancer 00:04:21 – Why his diagnosis brought decades of research to the forefront 00:05:23 – Bruce's belief that cancer is a symptom, not the underlying problem 00:06:23 – Why Bruce believes this message matters right now 00:07:25 – The biological imperative and humanity's drive to survive 00:08:22 – You are not a victim of your genetics 00:10:15 – Are 95% of our lives controlled by subconscious programming? 00:11:13 – How your subconscious takes over when you're thinking 00:12:46 – Why Bruce calls The Matrix a documentary 00:13:04 – Falling in love and escaping subconscious programming 00:14:27 – How to stay in the "honeymoon effect" 00:15:20 – Why the brain functions like a programmable computer 00:16:12 – The first seven years and the theta state 00:17:09 – How children download behavior from parents and community 00:18:08 – Bruce's childhood programming and failed relationships 00:18:39 – Rewriting his programming and finding lasting love 00:19:11 – Are you living your life or living your program? 00:20:11 – Your life as a reflection of subconscious beliefs 00:21:09 – Sponsor: Bite 00:23:24 – Why working harder doesn't necessarily change the program 00:23:55 – Bruce's claims about programming, stress, and disease 00:25:25 – Money, career, relationships, and the programs underneath them 00:26:18 – Why blaming others keeps you powerless 00:27:14 – Taking 100% responsibility for your life 00:28:18 – Hard experiences as opportunities to reorient your life 00:29:19 – Why victimhood means giving away your power 00:29:54 – How childhood can program our relationship with doctors and healing 00:31:14 – How beliefs can shape our perception of reality 00:32:04 – The centuries-old understanding of childhood programming 00:33:03 – How modern technology intensifies programming 00:34:03 – Challenging genetic determinism 00:34:31 – Genes as blueprints and the mind as architect 00:35:03 – Bruce's explanation of epigenetics 00:35:40 – Why Bruce compares the cell membrane to a computer chip 00:37:08 – Taking your power back 00:37:32 – How consumer culture programs desire 00:39:15 – Cooperation versus Darwinian competition 00:39:49 – When did life become a struggle? 00:41:28 – Rethinking "survival of the fittest" 00:42:30 – Resources, consumption, and the planetary pie 00:44:05 – Corporations and the economics of competition 00:45:46 – Environmental instability and the threat to our food system 00:47:43 – Why Bruce sees today's crisis as an evolutionary upheaval 00:48:15 – Moving beyond the belief that more is always better 00:49:11 – Bruce's theory about humans absorbing energy from the environment 00:50:18 – Food, free radicals, aging, and longevity 00:51:17 – Eating less, fasting, and longevity 00:52:09 – Why Darin still sees hope 00:53:16 – The garden isn't a battleground 00:53:51 – Cooperation, harmony, and our relationship with nature 00:55:21 – Indigenous wisdom and humanity's role as gardeners 00:57:03 – Life as creation instead of struggle 00:58:01 – How Bruce's study of immunology changed his spiritual worldview 00:59:09 – Cell receptors, identity, and Bruce's theory of the "field" 01:00:19 – The television and broadcast analogy for consciousness 01:01:22 – Bruce's interpretation of reincarnation 01:01:48 – Looking beyond race, gender, religion, and nationality 01:02:25 – Why Bruce believes we're here to manifest 01:03:20 – Creating heaven on Earth 01:04:43 – Bruce's claims about disease, genetics, stress, and programming 01:05:44 – Changing the program while the world is in chaos 01:06:34 – Darin's vision of communities that actually work 01:07:31 – Choosing where you put your focus 01:08:22 – Life is a gift, not a struggle 01:09:55 – Why Bruce believes knowledge is power 01:11:51 – Darin opens up about losing his mother 01:13:00 – Energy, grief, and nonverbal communication 01:14:10 – The power to create a different future 01:14:57 – Can a clear vision override subconscious programming? 01:15:35 – Bruce's interpretation of thoughts as an energy field 01:17:05 – How individual consciousness becomes collective consciousness 01:17:34 – Why community amplifies change 01:18:36 – Coherence versus the noise of the world 01:19:05 – Why you can't force someone else to change 01:19:59 – How many people does it take to shift collective consciousness? 01:21:04 – One candle can light up a dark room 01:22:05 – Why Bruce believes humanity is at an evolutionary turning point 01:22:39 – Surviving and thriving through massive change 01:23:23 – Surrounding yourself with people in harmony 01:24:04 – Community, gratitude, and final thoughts 01:24:36 – Closing Thank You to Our Sponsors: Bite Toothpaste: Go to trybite.com/DARIN20 or use code DARIN20 for 20% off your first order. Fatty15: Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/DARIN and using code DARIN at checkout. Join the SuperLife Community: Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien Find More from Bruce Lipton: Website: brucelipton.com Instagram: @brucelipton Buy His New Book: Beyond Darwin Find More from Darin Olien: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences Platform & Products: superlife.com New Show: Roadmap to Happiness Key Takeaway "You have to take your power back. Much of what shapes your life may be operating beneath conscious awareness, but Bruce's central message is that those patterns don't have to remain permanent. By becoming aware of the programs you're running, taking responsibility for what you're creating, and consciously choosing the beliefs, relationships, communities, and vision you want to reinforce, you can begin creating a life based less on fear and struggle and more on love, cooperation, and possibility."

Con Paloma Gallego, Arturo Téllez y Javier Ruiz, además del invitado Goyo Jiménez, humorista y actor.

Our dear friends invited us to an event this weekend in LA… they are partnering with Gary Brecka to build Ultimate Longevity Centers which will bring treatments and testing that just hasn't been easily accessible before now. I believe the way we look at aging is outdated and I'm going to share the biggest take aways I got from his on stage message and chatting with him one on one. We are talking about very practical starting points and Gary Brecka's actual morning health routine. Stop waiting until something is wrong to start taking care of your body. We have been taught this idea that getting older automatically means getting weaker, having less energy, gaining weight, losing muscle, sleeping worse, becoming more anxious, needing more medications and eventually developing all of the diseases that "run in our family." Gary challenges a lot of that thinking. His message is essentially… What if we became obsessed with keeping our bodies functioning incredibly well for as long as possible? What if instead of asking, "How do I treat disease once I have it?" we asked, "How do I create a body that is incredibly difficult for disease to thrive in?" And then there's the longevity piece that completely fascinates me. Gary believes we're entering a period where medicine, AI, biological data and longevity research are going to advance so rapidly that lifespan could look radically different in the future. Maybe 120. Maybe beyond. We don't know. But what we do know is that we need to keep ourselves healthy enough NOW to benefit from whatever becomes possible later. So today's episode is about doing the things that give you the strongest, healthiest, most capable body possible. I've been listening to Gary Brecka talk about health, longevity, anxiety, genetics, sleep, sunlight, oxygen, muscle, bloodwork and what he believes is coming next in longevity science. THE BIG IDEA: YOUR HEALTH IS BUILT EVERY DAY One of my biggest takeaways from Gary is that health isn't something we deal with when there's a problem. It's something we're building every single day. Your sleep last night matters. What you do when you wake up matters. Whether you move your body matters. Whether you maintain muscle matters. Your metabolic health matters. Your stress matters. Your relationships matter. Your nutrition matters. Your environment matters. And individually, none of these things feels life-changing. But repeated for years and decades… they become your life. Gary describes his routine as simple, portable and repeatable. I LOVE that. Because the best health routine isn't the $100,000 biohacking setup. It's the one you'll actually do every day. HABIT #1: HYDRATE BEFORE YOU DO ANYTHING ELSE Gary starts his morning with water and minerals. One version of his routine is a large glass of room-temperature water with mineral salt and sometimes lemon. His current routine also frequently includes mineral salt, hydrogen water and essential amino acids. Wake up and hydrate. You've just spent roughly eight hours without drinking anything. Don't make coffee your first liquid of the day. Put water next to your bathroom sink. Put it next to your coffee machine. Make it automatic. Gary likes mineral salt because sodium and other minerals participate in fluid balance and normal nerve and muscle function. HABIT #2: GET OUTSIDE FIRST THING Gary says to get outside within the first part of your morning and get natural outdoor light into your eyes. His routine generally calls for about 10 minutes outside. Morning light helps tell your brain: It's daytime. Start the clock. Light is one of the strongest environmental signals for the circadian system. Properly timed morning light can shift circadian timing earlier and increase daytime alertness. And I love thinking of sleep this way: Your good night's sleep starts in the morning. We tend to think sleep health starts when we crawl into bed. But your body has been receiving signals all day telling it when to be awake and when to prepare for sleep. HABIT #3: BREATHE ON PURPOSE Gary talks about oxygen constantly. His personal morning practice has included three rounds of deep breathing followed by breath holds. And this connects to another thing we've been talking about: Anxiety. I love the idea that when you feel anxious, you shouldn't immediately decide: "I'm an anxious person." Anxiety is a state your nervous system is experiencing. Sometimes your thoughts are driving your physiology. And sometimes your physiology can amplify anxious thoughts. Either way, changing the physical state can sometimes help change the mental state. Research on structured breathwork has found modest improvements in stress and anxiety, although it isn't a cure-all and the quality of studies varies. HABIT #4: GIVE YOUR BRAIN SILENCE Gary often combines his morning breathing with quiet, gratitude and reflection. He has described sitting quietly for around 10 minutes, looking toward the horizon or closing his eyes and thinking about gratitude. (PodScripts (https://podscripts.co/podcasts/the-ultimate-human-with-gary-brecka/246-gary-brecka-answers-googles-most-searched-questions-on-his-diet-wellness-and-lifestyle?utm_source=chatgpt.com)) Think about how different this is from what most of us do. Eyes open. Phone. Email. Instagram. News. Text messages. Stress. Other people's priorities. And we wonder why we feel overstimulated. TRY THIS: Before consuming everybody else's thoughts… Have some of your own. What am I grateful for? What matters today? Who needs me today? How do I want to feel today? What is actually important? PRACTICAL VERSION: Five minutes. That's it. No phone. No podcast. No input. Just quiet. HABIT #5: USE CONTROLLED DISCOMFORT Cold exposure is another major Brecka habit. If he has access to a cold plunge, he uses it. When traveling, he has said a cold shower works too. But I think there is a bigger lesson here than whether everybody needs to buy a cold plunge. Stop designing your entire life around comfort. Human beings are unbelievably adaptable. Exercise is stress. Heat is stress. Cold is stress. Fasting is stress. Challenging your brain is stress. The key is appropriate amounts of stress followed by recovery. HABIT #6: MOVE EARLY Gary includes movement in his morning routine. But here's what I love: It doesn't need to be a full workout. Walk. Stretch. Squat. Lift. Do yoga. Go outside. Movement tells your body: We're alive. We're using this machine today. And then keep moving after the morning is over. One exceptionally practical habit is walking after meals. Instead of finishing dinner and immediately sitting on the couch… WALK FOR 10 MINUTES. Moving skeletal muscle after eating can help the body handle glucose. You don't need workout clothes. You don't need a gym. You don't even need to sweat. Walk around your neighborhood. Walk your dog. Walk while you're on a phone call. ONE OF THE EASIEST HEALTH RULES: Eat → walk. HABIT #7: BUILD MUSCLE LIKE YOUR FUTURE DEPENDS ON IT This is where I think longevity conversations get really practical. MUSCLE IS NOT JUST ABOUT LOOKING GOOD. Maintaining muscle becomes increasingly important as we age. Resistance training is one of the most powerful non-drug strategies available for preserving and building skeletal muscle. Losing muscle eventually affects: strength balance mobility independence your ability to recover from illness your ability to do normal life You're not building your 2026 body. You're building your 2056 body. HABIT #8: PRIORITIZE PROTEIN AND REAL FOOD- avoid processed foods Gary emphasizes protein and essential amino acids because preserving lean tissue is a major part of his longevity philosophy. The research strongly supports resistance training for preserving muscle, while evidence regarding how much additional benefit comes from protein supplementation specifically is more mixed. HABIT #9: PROTECT YOUR METABOLIC HEALTH I think this deserves WAY more attention. We obsess over weight. Gary talks much more about metabolic health. There is a difference. Weight is one number. Metabolic health includes things like: blood glucose insulin sensitivity blood pressure blood lipids waist circumference fitness body composition Instead of only asking: "How much do I weigh?" Ask: "How well is my body functioning?" Someone can lose weight while losing muscle. Someone can be thin and still have poor metabolic health. PRACTICAL HABITS: Strength train. Walk. Walk after meals. Eat mostly whole foods. Get enough sleep. Maintain healthy body composition. Reduce constant snacking if it isn't serving you. Know your basic health numbers. THE GOAL ISN'T SKINNY. The goal is metabolically capable. HABIT #10: TEST… DON'T JUST GUESS This might be one of my favorite parts of Brecka's philosophy. Stop guessing about everything. If you're exhausted all the time… investigate. If you're unusually anxious… investigate. If your sleep has suddenly changed… investigate. If your energy has disappeared… investigate. If your hormones feel completely different… investigate. If you feel awful despite doing "everything right"… investigate. Don't immediately decide: "I'm getting old." "This runs in my family." "I'm just an anxious person." "My metabolism sucks." "This is just how I am." ASK BETTER QUESTIONS. Could something modifiable be contributing? sleep nutrient deficiencies thyroid function iron status medications hormones metabolic health stress alcohol caffeine environment psychological health This does NOT mean ordering every exotic test on the internet. It means becoming curious about your own biology. HABIT #11: DON'T TURN ANXIETY INTO YOUR IDENTITY This is worth repeating because I think this is such an important mental shift. Instead of: "I AM anxious." Try: "I'm experiencing anxiety." Those are very different statements. One is an identity. One is a temporary condition worth investigating. Gary's message leans heavily toward investigating biology. He talks about things like methylation pathways and MTHFR. There are legitimate genetic influences on anxiety. But anxiety is complex. Research suggests anxiety disorders arise through a combination of genetic vulnerability and environmental influences, not one single "anxiety gene." (PubMed (https://pubmed.ncbi.nlm.nih.gov/15699295/?utm_source=chatgpt.com)) So I would approach it from ALL DIRECTIONS: Calm the body. Investigate the biology. Work on the thoughts. Breathwork. Sleep. Exercise. Less overstimulation. Healthy relationships. Therapy when needed. Medical evaluation when something feels physiologically off. Nutrition. Less caffeine when appropriate. Time outdoors. Don't choose between: "It's psychological." or "It's biological." It can be both. HABIT #12: GENETICS ARE INFORMATION… NOT ALWAYS DESTINY This is another Gary Brecka concept that I think is incredibly empowering when we phrase it accurately. People say: "Diabetes runs in my family." "Anxiety runs in my family." "Heart disease runs in my family." "Autoimmune disease runs in my family." And we can start thinking: Well… I guess that's coming for me too. But genetics often represent susceptibility rather than certainty. Your genes can increase risk. Your environment can increase or decrease risk. Your behaviors matter. Your metabolic health matters. Your exposures matter. Your entire biological environment matters. So instead of thinking: "My family gets this disease." Think: "I may have inherited a vulnerability. What parts of that vulnerability can I modify?" THAT is empowering. Important distinction: Some diseases absolutely are caused by inherited genetic mutations. So we should not say: "Genetic diseases aren't real." They absolutely are. The better message is: Genes can load the gun. They don't always pull the trigger. And with many complex chronic diseases, what ultimately happens involves an interaction between genetics and environment. HABIT #13: STOP THINKING OF SLEEP AS LOST PRODUCTIVITY Sleep is when your body gets to repair. And Brecka's evening routine reflects this. He emphasizes regular sleep, reducing stimulation late at night and setting up the next morning by protecting the night before. My favorite way to think about sleep: Tomorrow starts tonight. Stop trying to squeeze another hour out of your day if it destroys tomorrow. Decide when you're going to bed BEFORE you're tired. Dim things down. Get off your phone. Stop working. Let the nervous system receive a signal that the day is ending. Pick a bedtime and protect it the same way you'd protect an important meeting. NOW LET'S TALK ABOUT LIVING TO 120 The speed of advancement is changing. AI can analyze enormous amounts of biological data. Diagnostics are improving. Scientists are studying the actual biology of aging rather than treating aging purely as an unavoidable decline. Researchers are investigating cellular senescence, epigenetics, regenerative medicine and other mechanisms associated with biological aging. Gary believes these developments could eventually change human lifespan dramatically. And his argument is essentially: Stay alive and stay healthy long enough to benefit from what's coming. That hit me HARD. Because imagine being 75 in the future… But instead of arriving at 75: metabolically sick weak frail sedentary cognitively struggling carrying multiple preventable chronic illnesses You arrive: strong metabolically healthy active engaged cognitively sharp sleeping well maintaining muscle surrounded by people you love THAT is the bridge. Not: "How do I live forever today?" But: "How healthy can I be when tomorrow's medicine arrives?" DON'T JUST CHASE LIFESPAN. CHASE HEALTHSPAN. I don't want to simply exist until I'm 120. I want to LIVE. I want to: travel walk everywhere lift my suitcase play with grandchildren hike swim think clearly learn new things have great conversations have energy be independent laugh have purpose wake up excited THAT is longevity. Not adding years at the end where you can't live. Adding life to the years. WHAT SHOULD WE ACTUALLY DO RIGHT NOW? If you took this entire episode and boiled it down into a daily longevity checklist… MORNING Hydrate. Get outside. Get natural morning light. Breathe intentionally. Spend a few minutes in quiet. Think about gratitude. Move your body. Use cold exposure if you enjoy it and it's appropriate for you. Don't immediately flood your brain with stress. DURING THE DAY Eat nutrient-dense real food. Prioritize protein. Strength train consistently. Walk. Walk after meals. Stay metabolically healthy. Maintain muscle. Build meaningful relationships. Have purpose. Keep learning. Get outside. NIGHT Stop eating mindlessly late into the evening. Reduce stimulation. Get off the phone. Give yourself a predictable bedtime. Sleep. THROUGHOUT YOUR LIFE Know your numbers. Do appropriate preventive screening. Investigate symptoms rather than ignoring them. Don't automatically assume something is "just aging." Don't automatically assume family history means destiny. Continue learning as science changes. Protect your muscle. Protect your metabolism. Protect your brain. Protect your relationships. Protect your sleep. THE SIMPLEST VERSION OF EVERYTHING GARY BRECKA IS SAYING 1. Get sunlight. 2. Breathe. 3. Hydrate. 4. Move. 5. Build muscle. 6. Eat real nutrient-dense food. 7. Protect your metabolism. 8. Sleep like it matters. 9. Challenge your body sometimes. 10. Investigate problems instead of simply accepting them. 11. Don't confuse genetic risk with guaranteed destiny. 12. Don't turn anxiety into your identity. 13. Build relationships and a life that gives you purpose. 14. Stay unbelievably healthy while longevity science continues advancing. And maybe most importantly… DON'T WAIT UNTIL YOU'RE SICK TO BECOME INTERESTED IN YOUR HEALTH. I learned that every single thing that gives me the best chance of being healthy at 120 also gives me a better life at 45. Getting sunlight tomorrow morning makes tomorrow better. Sleeping tonight makes tomorrow better. Building muscle makes this decade better. Eating well makes today better. Getting outside makes today better. Putting my phone down makes today better. Managing anxiety makes today better. Having people I love around me makes today better. So this isn't really an episode about trying to cheat death. It's about refusing to sleepwalk through your health. Your body is the vehicle that carries you through every single experience you're hoping to have. Every trip. Every adventure. Every business idea. Every dinner. Every workout. Every moment with your kids. Every future grandkid. Everything. So take ridiculously good care of it. And instead of looking at aging and thinking… "Well, I guess everything starts going downhill from here…" What if we thought completely differently? What if our goal was: I want to be stronger next year. Healthier next year. More metabolically healthy next year. More informed next year. More capable next year. And then do it again. And again. And again. For decades. Let's make the goal to be fully alive for as much of it as humanly possible. That's the health lesson I'm taking from Gary Brecka. Don't wait for the future of longevity medicine. Build the kind of body today that's ready for it.

What if your genes aren't your destiny? Cell biologist Bruce Lipton PhD — the former medical school professor whose cloned stem cell research helped pioneer epigenetics, and author of The Biology of Belief (published in over 50 languages) — joins Robert Lufkin MD to make the case that perception, not DNA, controls your biology. A positive belief can heal (the placebo effect); a negative belief can harm (the nocebo effect) — which is why Bruce calls a prognosis a prescription. And now, after a cancer diagnosis at 80, he is living his science in the most personal way imaginable. His new book, Beyond Darwin: How Epigenetics, Quantum Science, and Cooperation Shape Humanity's Future, releases today — the same day as this episode. Chapters: 00:00 — Introduction 02:36 — The Stem Cell Experiment That Broke the Dogma 05:55 — Epigenetics: Control Above the Gene 09:12 — The Brain Is the Chemist: Beliefs Become Biology 12:04 — Cancer Is Not Genetic: The Adoptee Data 20:43 — Placebo and Its Dark Twin, the Nocebo 23:34 — Prognosis as Prescription: Delivering a Diagnosis 30:36 — Stem Cells: Your Built-In Repair System 32:46 — Bruce's Cancer at 80 and the Younger Doctors 40:16 — Programmed in the First Seven Years 44:05 — Conscious vs Subconscious: The 95% Problem 48:34 — The Matrix, the Red Pill, and Falling in Love 50:55 — Why Marriages Fall Apart: Living From the Program 55:54 — A New Generation of Medicine 57:53 — Civilization's Programming and Conscious Evolution Key takeaways: Genetically identical stem cells became muscle, bone, or fat depending only on their environment — the culture medium, not the genes, determined their fate. Fewer than 1% of diseases are caused by genes alone; adoption studies show adoptees acquire the disease patterns of their adoptive families, not their biological ones. The brain is the chemist: perception shapes blood chemistry, which controls gene expression. Placebo beliefs can heal — and nocebo beliefs can harm. A substantial share of treatment outcomes reflects belief effects. Your body replaces roughly 3.5 million cells every second, powered by stem cells — your built-in repair system. About 95% of daily behavior runs on subconscious programs downloaded in the first seven years of life. Change the program — through mindfulness, presence, and repetition — and you change your biology. Studies & sources: Sørensen et al., NEJM 1988 — premature death in adoptees tracks adoptive, not biological, parents: https://pubmed.ncbi.nlm.nih.gov/3347221/ Rooney et al., Health Psychology 2024 — meta-analysis of nocebo effects: https://pubmed.ncbi.nlm.nih.gov/37843534/ Colloca & Miller 2011 — the nocebo effect and its clinical relevance: https://pmc.ncbi.nlm.nih.gov/articles/PMC3167012/ Kaptchuk & Miller, NEJM 2015 — placebo effects in medicine: https://www.nejm.org/doi/10.1056/NEJMp1504023 Motesharrei et al., Ecological Economics 2014 — the NASA-funded HANDY model on societal sustainability: https://nature.berkeley.edu/garbelottoat/wp-content/uploads/motesharrei-etat-2014.pdf Bruce Lipton's new book, Beyond Darwin (BenBella): https://benbellabooks.com/shop/beyond-darwin/ Watch the full episode on YouTube: https://youtu.be/6BnJVoo_iXs Robert Lufkin MD's book, Lies I Taught in Medical School: https://robertlufkinmd.com/lies/ Newsletter: https://robertlufkinmd.substack.com Website: https://robertlufkinmd.com The information provided in this program is for general informational purposes only and is not intended as a substitute for professional medical advice. Always consult your physician regarding your personal health decisions.⭐ Enjoying the show? Please leave a 5-star review on Apple Podcasts — it takes 30 seconds and helps more people discover the science of health and longevity. Thank you!New episodes every other Tuesday. Subscribe so you don't miss one.Continue this conversation on Substack: https://robertlufkinmd.substack.comLies I Taught In Medical School — Free sample chapter: https://www.robertlufkinmd.com/lies/Web: https://www.robertlufkinmd.comYouTube: https://www.youtube.com/robertlufkinmdX: https://x.com/robertlufkinmdInstagram: https://www.instagram.com/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinLinkedIn: https://www.linkedin.com/in/robertlufkinmd/

Owen Matela is 6-foot-6 with a basketball player's frame—his dad played college ball at Bowling Green and overseas in Belgium, where Owen was born. But the Lyons senior chose football – and the Miami (Ohio) commit is just scratching the surface to his potential in the sport.Become a supporter of this podcast: https://www.spreaker.com/podcast/friday-night-drive--3534096/support.

Methylation is a chemical process running billions of times per second inside your body — and when it slows down, you feel it as fatigue, low mood, brain fog, and hormone symptoms. Nurse Doza breaks down what methylation actually does, why the MTHFR gene variant makes the cycle run less efficiently, why folic acid is the wrong form of folate if you carry it, and the four steps that support your methyl donor supply. FEATURED PRODUCT Bliss (Mood Booster) — $129 Bliss is a lemon-flavored daily stick pack built around TMG (trimethylglycine) — a naturally occurring methyl donor. It is formulated to support the biochemical reactions that require methyl groups: neurotransmitter synthesis and healthy mood, the conversion of homocysteine to glutathione, and liver health.* If the episode described you — normal labs, still running on empty — Bliss is the piece that feeds the cycle directly instead of asking your genetics to do the conversion work.

What if the genes you've been blaming for your health struggles were never the problem to begin with? Your "bad" genetic hand might actually be a survival advantage in disguise, and the issue may be that you're not optimizing your lifestyle to the genes you have. In this episode, Dr. Sam Shay, founder of FitGenes and a genetics expert with over a decade of clinical experience, explains why analyzing the right genes matters far more than chasing trendy ones, such as MTHFR. If you've ever felt betrayed by your own body, this episode offers a completely different, more empowering way to see your genetics. Listen now and start optimizing your body today! For show notes, visit https://fivejourneys.com/podcasts/you-dont-have-the-wrong-genes-youre-in-the-wrong-environment/  Follow us on Instagram at https://www.instagram.com/feelfreakingamazing/ Related Episodes: Beyond Diets: How Your Genes Reveal the Ideal Eating Plan for You, with Dr. Sam Shay Live Longer by Activating Your Body's Anti-Aging Gene, with Dr. Bill Andrews From Toxic Diet Culture to Food Peace, with Dr. Will Cole Functional Nutrition vs. Dieting: What Actually Works, with Andrea Nakayama Identifying Food Intolerances Using The New Whole30, with Melissa Urban

In this episode I sit down with epigenetic longevity strategist Chris Barnes to explore how our genes influence our health, and why our genetics don't necessarily determine our future.Together, we unpack the science of epigenetics, how everyday choices like sleep, nutrition, movement and stress can influence gene expression, and why a personalised approach to health may be more effective than blindly following the latest diet, supplement or longevity trend.What we cover:What epigenetics is and how your lifestyle can influence gene expressionWhy your genetics aren't necessarily your health destinyHow genetic and epigenetic testing can help personalise your approach to healthWhy more supplements, biohacking and health data aren't always betterThe simple daily habits Chris believes can support long-term health and longevityWhether you're focused on high performance, longevity or simply having more energy for the people and things that matter most, this conversation is a fascinating look at why understanding your individual biology could help you make better decisions about your health.Learn more about Chris here - https://chrisbarneswellness.com.au/about-wellness-programs/Follow Chris on IG - https://www.instagram.com/chrisbarneswellness/Connect with Chris on LinkedIn - https://www.linkedin.com/in/chris-barnes-wellness/If you're interested in having me deliver a keynote or workshop for your team contact Caroline at caroline@jjlaughlin.comWebsite: https://www.jjlaughlin.com YouTube: https://www.youtube.com/channel/UC6GETJbxpgulYcYc6QAKLHA Facebook: https://www.facebook.com/JamesLaughlinOfficial Instagram: https://www.instagram.com/jameslaughlinofficial/ Apple Podcast: https://podcasts.apple.com/nz/podcast/life-on-purpose-with-james-laughlin/id1547874035 Spotify: https://open.spotify.com/show/3WBElxcvhCHtJWBac3nOlF?si=hotcGzHVRACeAx4GvybVOQ LinkedIn: https://www.linkedin.com/in/jameslaughlincoaching/James Laughlin is a High Performance Leadership Coach, Former 7-Time World Champion, Host of the Habits of High Performers Podcast and an Executive Coach to high performers and leaders. James is based in Christchurch, New Zealand.Send me a personal text message - If you're interested in booking me for a keynote or workshop, contact Caroline at caroline@jjlaughlin.comSupport the show

El presidente del CTA analiza en 'Carrusel' las novedades del arbitraje español, el VAR y la inteligencia artificial

A 2025 study found that exposure to certain PFAS chemicals, which are pervasive and persistent in the environment and human bodies, can lead to changes in gene expression that are linked to cancers, autoimmune and other immune disorders, and neurological disorders.    Also, the four astronauts of the Artemis II mission in April 2026 made new scientific observations that are helping to expand our knowledge of the Moon, as well as the Earth itself. Artemis II Lunar Science Lead Kelsey Young joins us to talk about the scientific goals and accomplishments of the mission and the unforgettable moments the crew shared with people back on Earth.   And climate solutions like renewable energy tech that requires intensive mining can run into skepticism from people across the political spectrum. But according to data scientist Hannah Ritchie, many of the concerns are based on partial- and misinformation, and the outlook for addressing the climate emergency isn't as grim as some people may think. Ritchie is the author of Clearing the Air: A Hopeful Guide to Solving Climate Change in 50 Questions and Answers.    ---  You can help support our free public radio show and podcast, for free, by leaving a review on Apple Podcasts. It's one of the best ways to help other listeners find Living on Earth!  Learn more about your ad choices. Visit megaphone.fm/adchoices

Stop Guessing: Your Genes Reveal the Best Diet & Workout Click On My Website Below To Schedule A Free 15 Min Zoom Call:www.Over40FitnessHacks.comOver 40 Fitness Hacks SKOOL Group!Get Your Whoop4.0 Here!Dr. Sam Shay - Genetics TestingFitGenesUSA.comDrSamShay.comIn this episode of Over 40 Fitness Hacks, I sit down with returning guest Dr. Sam Shay, Functional Medicine Certified Practitioner and Western Hemisphere Director of FitGenes USA, to explore the latest advancements in genetic testing for health, fitness, and longevity. Building on our previous conversation about the "10 Pillars of Health," Dr. Shay explains why genetic testing provides the blueprint for making smarter decisions about nutrition, exercise, recovery, and biohacking.Dr. Shay discusses how most genetic reports overwhelm people with hundreds of confusing data points, while FitGenes focuses on prioritizing the most actionable genes related to inflammation, mitochondrial function, detoxification, vitamin D metabolism, methylation, cardiovascular health, and fat metabolism. Instead of generating information overload, the goal is to provide clear lifestyle recommendations that have the greatest impact.We also dive into one of the most fascinating aspects of the conversation: using genetics to determine your ideal diet. Dr. Shay explains how copy number analysis of the AMY1 gene can reveal whether your body is naturally better suited for a ketogenic, paleo, Mediterranean, or higher-carbohydrate diet. He shares how discovering his own genetic carb tolerance dramatically improved his energy, digestion, mood, and overall health after years of following the wrong eating plan.Beyond nutrition, we discuss how genetics can guide exercise programming by identifying whether you're genetically predisposed for endurance or power training, your risk for exercise-induced inflammation, collagen strength, injury susceptibility, and recovery needs. Dr. Shay emphasizes that many people unknowingly overtrain simply because they're following popular fitness trends instead of training according to their genetic blueprint.Dr. Shay also gives viewers an inside look at the redesigned FitGenes reports, showing how they summarize key recommendations on a single page—including ideal diet, top nutrient priorities, exercise type, recovery strategies, and food sensitivities—making the information practical for both practitioners and everyday users.Throughout our discussion, we talk about why genetics should be one of the first investments for anyone interested in biohacking or longevity. Unlike other health metrics that change over time, your DNA never changes, making genetic testing a lifelong roadmap that can help guide future lab work, supplementation, nutrition, and training decisions.If you're interested in personalized health optimization and want to stop guessing which diets, supplements, or exercise programs are right for you, this episode provides an excellent introduction to how genetic testing can help create a personalized blueprint for lifelong health and performance.If you're interested in online personal training or being a guest on my podcast, "Over 40 Fitness Hacks," you can reach me at brad@over40fitnesshacks.com or visit my website at:Over40FitnessHacksAdditionally, check out my Yelp reviews for my local business, Evolve Gym in Huntington Beach, at https://bit.ly/3GCKRzVDisclaimer: The information provided on this podcast, including interviews and recommendations, is for educational and entertainment purposes only. It does not constitute medical, nutritional, or professional fitness advice. The hosts and guests are not your personal doctors or trainers. Always consult a qualified medical professional before changing your diet, starting a new exercise regimen, or implementing any advice heard on this show. Use of any information provided is solely at your own risk.

What if food is doing far more than providing calories, protein, carbohydrates, and fat? What if every bite is actually delivering information to your genes, cells, microbiome, and biological systems? In this fascinating solo episode, Darin challenges the century-old idea of viewing food simply as fuel and explores what happens when we begin seeing food as biological information. From carrots resembling eyes and walnuts resembling brains to nutrigenomics, plant compounds, biophotons, structured water, living enzymes, and the microbiome, Darin dives into the hidden layers of food that never appear on a nutrition label. He explores established research alongside emerging and controversial areas of science, explaining why the freshness, color, diversity, and wholeness of what we eat may matter far beyond its calorie count. Darin also reveals why "eating the rainbow" is really about consuming a wider library of chemical information and why feeding your gut microbes may be just as important as feeding yourself. This episode will completely change the way you look at what's sitting on your plate. What You'll Learn Why Darin believes the calorie model leaves out some of food's most important biological effects How nutrients and plant compounds can influence gene expression through nutrigenomics and epigenetics Why Darin describes every meal as sending a "memo" to your DNA What biophotons are and the emerging research around light emitted by living cells and foods Why fresh, living foods may carry information that heavily processed foods have lost The theory of structured or "exclusion zone" water in living foods What happens to naturally occurring enzymes when foods are heated and processed Why the colors of fruits and vegetables correspond to different families of protective plant compounds How your food communicates with the trillions of microbes living inside your gut Why dietary diversity and fermented foods may help create a healthier, more resilient microbiome Chapters 00:00:00 – Welcome to SuperLife 00:00:32 – Sponsor: Bite 00:02:47 – The hidden clues sitting inside your food 00:03:22 – Carrots, tomatoes, and walnuts: coincidence or clues? 00:04:13 – Why we've been too busy counting calories 00:04:39 – Food is information 00:04:47 – Why the calorie model leaves out the bigger picture 00:05:14 – Your body isn't a furnace 00:05:48 – How food communicates with your cells 00:06:25 – Nutrigenomics: how food talks to your genes 00:06:53 – Every meal can influence gene expression 00:07:22 – What memo are you sending your DNA? 00:07:52 – The strange science of biophotons 00:09:03 – Why fresh food emits different light than processed food 00:09:37 – Where biophoton research stands scientifically 00:10:26 – Structured water and the fourth phase of water 00:12:00 – What processing may do to water inside food 00:12:37 – Sponsor: Manna Vitality 00:14:35 – The controversial theory of food enzymes 00:15:18 – What we know about enzymes in raw and sprouted foods 00:15:37 – The hidden information missing from nutrition labels 00:15:58 – Can the color of your food unlock your potential? 00:16:16 – Why "eat the rainbow" is chemistry, not mysticism 00:16:38 – Anthocyanins and the power of purple, red, and blue foods 00:17:27 – Color is the plant's natural label 00:18:20 – Every color sends your body a different message 00:18:50 – The problem with the modern "beige diet" 00:19:14 – You're feeding 38 trillion microbes, not just yourself 00:19:46 – How gut bacteria transform fiber into powerful compounds 00:20:25 – The extraordinary conversation between plants and your microbiome 00:21:05 – Why plant diversity matters for immunity, mood, and hormones 00:21:31 – The Stanford fermented food study 00:22:02 – What fermented foods did to microbiome diversity and inflammation 00:22:30 – Ultra-processed food, inflammation, and what's coming next 00:22:45 – Continue the full deep dive on Patreon 00:23:24 – Closing thoughts Thank You to Our Sponsors Bite Toothpaste: Go to trybite.com/DARIN20 or use code DARIN20 for 20% off your first order Manna Vitality: Go to mannavitality.com/ and use code DARIN12 for 12% off your order. Join the SuperLife Patreon: This is where Darin now shares the deeper work: - weekly voice notes - ingredient trackers - wellness challenges - extended conversations - community accountability - sovereignty practices Join now for only $7.49/month at https://patreon.com/darinolien Find More from Darin Olien: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences Platform & Products: superlife.com New Show: Roadmap to Happiness Key Takeaway "Food isn't just fuel. Every bite carries information—through nutrients, plant compounds, color, fiber, enzymes, and the interactions it creates with your microbiome. Your body isn't simply counting calories; it's responding to biological signals. So the question isn't only how much you're eating. It's what message you're sending your body every time you sit down to eat." Bibliography/Sources: Food as Information & Nutrigenomics Dutton, R. (2017). Hey, Hippocrates: Food isn't medicine. It's just food. STAT News . https://www.statnews.com/2017/04/10/hippocrates-food-medicine/ Genes and diet in the prevention of chronic diseases in future generations. (n.d.). PubMed Central . https://pmc.ncbi.nlm.nih.gov/articles/PMC8900696/ Müller, M., et al. (2026). Nutrigenomics and the interface between diet and gene expression. ScienceDirect . https://www.sciencedirect.com/ Nutriepigenomics. (n.d.). In Wikipedia . https://en.wikipedia.org/wiki/Nutriepigenomics Stover, P. J., & Garza, C. (n.d.). Food as exposure: Nutritional epigenetics and the new metabolism. PubMed Central . https://pmc.ncbi.nlm.nih.gov/articles/PMC6486241/ Biophotons & Structured Water Bio-photons: The light in your cells, food & water. (n.d.). Watermatters . https://www.yourwatermatters.com/ Biophotons may shed new light on body and brain activity. (2025). Psychology Today . https://www.psychologytoday.com/ Pollack Laboratory. (n.d.). University of Washington. https://pollacklab.org/ Pollack, G. H. (2013). The fourth phase of water: Beyond solid, liquid, and vapor. Ebner & Sons Publishers . The legacy of light: Fritz-Albert Popp and the biomedical power of biophotons. (n.d.). Dr. Clark Store . https://drclarkstore.com/ Enzymes, Sprouting & Traditional Diets Characteristics of traditional diets. (n.d.). The Weston A. Price Foundation . https://www.westonaprice.org/ Edward Howell, MD. (n.d.). The Weston A. Price Foundation . https://www.westonaprice.org/ Germination: An alternative source to promote phytonutrients in edible seeds. (n.d.). Food Quality and Safety . https://academic.oup.com/fqs Howell, E. (1985). Enzyme nutrition: The food enzyme concept. Avery . Nutritional and end-use perspectives of sprouted grains: A comprehensive review. (2021). Food Science & Nutrition . https://onlinelibrary.wiley.com/doi/full/10.1002/fsn3.2477 Price, W. A. (1939). Nutrition and physical degeneration. Price-Pottenger Nutrition Foundation . Study on effect of germination on flavonoid content and nutritional value of different varieties of chickpeas. (2024). PubMed Central . https://pmc.ncbi.nlm.nih.gov/articles/PMC10787121/ Phytonutrients & Colors Anthocyanidins and anthocyanins: Colored pigments as food, pharmaceutical ingredients, and the potential health benefits. (2017). Food & Nutrition Research . https://pmc.ncbi.nlm.nih.gov/articles/PMC5613902/ Anthocyanins as key phytochemicals acting for the prevention of metabolic diseases. (n.d.). PubMed Central . https://pmc.ncbi.nlm.nih.gov/articles/PMC6489379/ The therapeutic potential of anthocyanins: Current approaches based on their molecular mechanism of action. (2020). Frontiers in Pharmacology . https://www.frontiersin.org/articles/10.3389/fphar.2020.01300/full Microbiome, Fiber & Fermented Foods From dietary fiber to host physiology: Short-chain fatty acids as key bacterial metabolites. (2016). Cell . https://www.cell.com/cell/fulltext/S0092-8674(16)30559-6 Stanford Medicine. (2021, July). Fermented-food diet increases microbiome diversity, decreases inflammatory proteins, study finds . https://med.stanford.edu/news/all-news/2021/07/fermented-food-diet-increases-microbiome-diversity-lowers-inflammation The mutual effect of dietary fiber and polyphenol on gut microbiota. (2025). ScienceDirect . https://www.sciencedirect.com/ Shape, Biomimicry & Botanical History Cardenas, D. (2013). Let not thy food be confused with thy medicine: The Hippocratic misquotation. e-SPEN Journal . https://doi.org/10.1016/j.clnme.2013.10.002 How do the 'three sister' plants work together? (n.d.). Soils Matter . https://soilsmatter.wordpress.com/ Kimmerer, R. W. (2013). Braiding sweetgrass: Indigenous wisdom, scientific knowledge, and the teachings of plants. Milkweed Editions . Nutritional benefits of lycopene and beta-carotene: A comprehensive overview. (n.d.). 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Hoy 13 de agosto es el Día Internacional de los Zurdos Esta fecha fue creada en 1976 por Dean R. Campbell, fundador de la organización americana Lefthanders International encargada de representar y defender los intereses de las personas zurdas. El objetivo de este día es dar a conocer los retos de usar la mano izquierda en un mundo creado para personas diestras. Se instauró como Día Internacional en 1992.

Anxiety in perimenopause isn't a mood problem — it's a clearance problem. Liz Roman and Becca Chilczenkowski break down COMT, GAD1 and FUT2: the three genes that decide how fast you clear adrenaline, whether you can build GABA, and whether your gut can grow the bacteria that make it. Plus why L-glutamine can make anxiety worse, why oral GABA mostly doesn't work, the lab markers hiding in plain sight on your standard panel, and why "your genes didn't change — your estrogen did." *** CONNECT:

Manny Maminakis is the inventor and CEO of Cannamatrix INC, a cannabis bioinfomratics platform. Prior to Cannamatrix, Manny spent 12 years in the cannabis industry as an award winning cannabis cultivator and edible chef. At CannMed 26, he presented a poster titled “Computational Identification of Volatile Sulfur Compound Synthase Homologs in Cannabis sativa Using Profile Hidden Markov Models” During our conversation, we discuss: What volatile sulfur compounds (VSCs) are and why they give certain cannabis strains their skunky, garlicky smell How Manny’s path from cannabis cultivator and award-winning edible chef led him into bioinformatics at Canimatrix Why the GMO (“garlic mushroom onion”) cultivar was chosen as the ideal candidate for studying VSCs How hidden Markov models were used to find candidate VSC genes by comparing cannabis proteins to garlic, onion, and other sulfur-producing plants And more! Thanks to This Episode’s Sponsor: Cannamatrix Cannamatrix is a genetic software company that empowers growers to select the best of the best from their seed stock. Their patented system of genetic testing with predictive algorithms helps growers harness the maximum potential of Cannabis while preserving the natural genetic makeup and reducing resource allocation, and saving time and money! Visit cannamatrix.com to learn more Related Resources @MannytheCannaBiologist on IG Review the Podcast CannMed Archive

Bioweapons are cheaper and deadlier than nukes — and we're not ready. Biological War author Annie Jacobsen breaks down how close we are to catastrophe.Full show notes and resources can be found here: jordanharbinger.com/1367What We Discuss with Annie Jacobsen:The Soviet bioweapons program was not dismantled after the Cold War — it was absorbed. The State Department says Russia and North Korea run active illegal programs; China and Iran are of concern.Bioweapons have a low barrier to entry, needing no uranium or missiles. Experts say one could be made in a basement with basic biology and AI help. The Pentagon rates bio the greatest overall WMD threat.Pneumonic plague is 100% fatal without antibiotics within 24 hours. The US has roughly 100 special-pathogen beds for 340 million people, so hospitals would be overwhelmed on day one.Soviet scientists inserted a euphoria gene into plague so the infected feel good, stay social, and spread it widely instead of staying home in bed.Annie Jacobsen's message is pressure, not panic — a human-made problem has a human solution. Pause risky gain-of-function research, depoliticize the threat, and communicate clearly so leaders can act in time.And much more...And if you're still game to support us, please leave a review here — even one sentence helps! Sign up for Six-Minute Networking — our free networking and relationship development mini course — at jordanharbinger.com/course!Subscribe to our once-a-week Wee Bit Wiser newsletter today and start filling your Wednesdays with wisdom!Do you even Reddit, bro? Join us at r/JordanHarbinger!This Episode Is Brought To You By Our Fine Sponsors: Article: Visit article.com/jordan for $50 off your first purchase of $100 or moreBetterHelp: 10% off first month: betterhelp.com/jordanBoll & Branch: 15% off first set of sheets: bollandbranch.com, code JORDANProgressive Insurance: Free online quote: progressive.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.