Podcasts about genes

Sequence of DNA or RNA that codes for an RNA or protein product

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Best podcasts about genes

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Latest podcast episodes about genes

Chente Ydrach
APARECEN IMÁGENES REVELADORAS DE DIDDY

Chente Ydrach

Play Episode Listen Later Nov 7, 2025 72:06


The Soil Matters With Leighton Morrison and Dr. Av Singh
Rewriting Your Health Story: Genes Are the Load, Lifestyle Pulls the Trigger

The Soil Matters With Leighton Morrison and Dr. Av Singh

Play Episode Listen Later Nov 7, 2025 45:26


Stop Settling for Shortcuts: Why Quick Fixes Are Failing Your Health” When did we start believing that a pill a day keeps the problem away? In this episode of Chiropractic is Se*y, we're exposing the trap of “easy-button” healthcare. We share a conversation with a patient who was taking a nightly Prilosec without ever asking why he needed it—or what it might be doing long term.We also tackle a big myth: that you're stuck with the health outcomes your parents had. You are not a victim of your genes. Your environment, choices, and habits turn genes on or off—this is the science of epigenetics, and it's empowering once you understand it.Tune in as we talk about:The family legacy of lifestyle-driven illnessHow discomfort is actually a signal (not a nuisance)Why foundational health work matters more than symptom reliefEpigenetics: how your environment influences gene expression

CBC News: World at Six
Another Tory MP out, ostrich farm cull, U.S. cuts flights, finding cancer in your genes, and more

CBC News: World at Six

Play Episode Listen Later Nov 6, 2025 29:00


Conservative MP Matt Jeneroux resigns from Parliament. His decision didn't come with an explanation. It makes it more likely the Liberals will be able to pass the federal budget in a few weeks. Also: The CFIA moves in to cull an ostrich herd in B.C., after a fight that went all the way to the Supreme Court.And: The U.S. government shutdown could have an effect on your travel plans. Airports at major hubs across the U.S. are cutting the number of flights starting tomorrow. The Federal Aviation Administration says, because of the shutdown, air traffic controllers are working without pay. And many have not been coming in to work.Plus: Researchers will test a hundred thousand people in Ontario to see if they carry genes that put them at a higher risk of cancer and heart disease, COP30 begins in Brazil, will a boost in funding for school meals be enough, and more.

Relatos Forenses Podcast
Ep. 172 Especial de terror "Del laboratorio a la tumba: los orígenes del horror” | Relatos Forenses Podcast

Relatos Forenses Podcast

Play Episode Listen Later Nov 6, 2025 104:39


Desde tiempos antiguos, la oscuridad ha inspirado historias que despiertan el miedo y la curiosidad del ser humano. Entre sombras y leyendas surgen figuras como Frankenstein, las Momias de Guanajuato, los Zombies y los Vampiros: seres que desafían la muerte y caminan entre los vivos. Cada uno guarda un secreto distinto, la ciencia prohibida, la maldición eterna, el regreso del más allá o la sed de sangre; pero… ¿todas estas historias pueden ser reales? ¡Descúbrelo! Learn more about your ad choices. Visit megaphone.fm/adchoices

Radio Jódar
Siguen apareciendo nuevos hallazgos en torno al paraje de El Fontanar, sobre el monumento de hierogamia (Acto sexual entre Diosa y Héroe), nuevas imágenes incrustadas en el

Radio Jódar

Play Episode Listen Later Nov 6, 2025 71:04


AUDIO con presentación y conferencia, íntegra, de Arturo Ruiz, sobre el monumento de El Fontanar

Truth About Dyslexia
Updated 2 Genes I see in neurodivergent thinkers

Truth About Dyslexia

Play Episode Listen Later Nov 5, 2025 16:14


In this conversation, Stephen Martin discusses the interplay between genetic and epigenetic factors in neurodiversity, particularly focusing on ADHD, dyslexia, and autism. He emphasizes how modern environments, especially the prevalence of addictive substances and social media, exacerbate these genetic predispositions, leading to increased struggles for individuals with these conditions.TakeawaysThere is a significant genetic and epigenetic component to ADHD, dyslexia, and autism.Many individuals are predisposed to various neurodiverse conditions.Modern environments contribute to the expression of genetic predispositions.Addictive substances and dopamine abusers are more prevalent today.Social media usage, like scrolling on TikTok, can exacerbate genetic struggles.The current environment is revealing more about our genetic codes.The interaction between genetics and environment is crucial in understanding neurodiversity.Increased screen time may lead to heightened challenges for neurodiverse individuals.Understanding neurodiversity requires a holistic view of genetics and environment.Awareness of these factors can lead to better support for those with neurodiverse conditions.ADHD, dyslexia, autism, epigenetics, genetics, neurodiversity, dopamine, social media, environment,  adults with dyslexia, support for adults.Join the clubrightbrainresetters.comGet 20% off your first orderhttps://addednutrition.comIf you want to find out more visit:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠truthaboutdyslexia.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Join our Facebook Group⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠facebook.com/groups/adultdyslexia⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

La Diez Capital Radio
Orígenes (05-112025)

La Diez Capital Radio

Play Episode Listen Later Nov 5, 2025 112:11


Conocemos el gran trabajo de la Fundación Canaria Buen Samaritano, gracias al Padre Pepe y nos presenta teatro con la obra "Bismillah, Historias Migrantes" un trabajo hecho por jóvenes que vienen desde África y son fruto de la emigración. Y desde Adeje la Asociación Cultural Imoque nos trae un día de tradiciones bajo el título de IDENTIDAD y que celebra así su IX Festival. Desde Gran Canaria, hablamos con Gregorio Díaz de la Agrupación Cultural Erasmo Hernández, una exposición donde los tocados de nuestra vestimenta son lo importante a destacar. Por otro lado se inauguran los Belenes, hablamos con Santy González y el nacimiento de la Casa de la Semilla, una tradición que cumple 33 ediciones. Desde Lanzarote Ricardo Reguera nos invita a seguir conociendo y aprendiendo sobre nuestra vestimenta por iniciativa de la Asociación Musical Culyural Guágaro y como cada semana nos vamos a escena con Zálatta Teatro en La Diez Capital Radio con Joam Walo "poniendo lo canario más de moda que nunca y apostando por lo nuestro" #origenes #programaorigenes #ladiezradio #capitalradiogc #joamwalo

Voces de Ferrol - RadioVoz
FERROLANOS POR EL MUNDO: Juan Luis Montero, el arqueólogo ferrolano que busca los orígenes de la humanidad en Irak

Voces de Ferrol - RadioVoz

Play Episode Listen Later Nov 5, 2025 12:43


El profesor de Historia Antigua de la Universidade da Coruña, Juan Luis Montero Fenollos, acaba de regresar de una misión arqueológica en Mosul, al norte de Irak, donde representó a la UDC como único arqueólogo español en una expedición internacional junto a expertos del Museo del Louvre y la Universidad de la Sorbona. Hoy en RadioVoz Ferrol, Montero relató su experiencia excavando en una de las ciudades asirias más grandes del mundo, una urbe de 400 hectáreas considerada “el lugar donde empezó la historia”. Pese a las difíciles condiciones del entorno y los estrictos controles de seguridad, el arqueólogo destaca la acogida y generosidad del pueblo iraquí y la importancia de la cultura como herramienta para reconstruir sociedades tras la guerra. “Transformar un lugar de violencia en un lugar de conocimiento es una forma de paz”, afirmó. Ferrol, una vez más, tiene un embajador del saber en el corazón de la antigua Mesopotamia.

UNPILLED Podcast
The Importance of Lifestyle, Genetics, and Community in Preventing Dementia with Julia Lundstrom

UNPILLED Podcast

Play Episode Listen Later Nov 4, 2025 55:21


"When your brain is the happiest and healthiest it could be, you are the happiest and healthiest that you can be."When we choose to live with a healthier lifestyle, we get to have better chances of preventing dementia. In this episode, Dr. Krista Kostroman is joined by Julia Lundstrom, CEO and Founder of Simple Smart Science. Julia is an author and neuroscience and brain health educator who travels the country teaching and speaking to groups on how to improve their memories, naturally. She has taught her strategies to over 345,000 people, providing expertise in the field of memory, dementia, alzheimer's, and personalizing one's health journey to reversing cognitive decline.Join us as we uncover the strategies in preventing dementia as we dive into accessing the 10 pillars of brain health, discussing which genes greatly impact your brain, and what you can do about it.If you wish to learn more from Julia Lundstrom and Simple Smart Science, you may do so through the following channels:Website: https://www.simplesmartscience.com/YouTube: https://youtube.com/@simplesmartscienceFacebook: https://www.facebook.com/SimpleSmartScience______________________________________________________Keep yourself up to date on The DNA Talks Podcast! Follow our socials below:The DNA Talks Podcast Instagram: @dnatalkspodcastThe DNA Company Instagram: @thednacoThe DNA Company's Official Tiktok Account: @thednaco3______________________________________________________Medical Disclaimer: The information provided in this communication is for general informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read here. If you think you may have a medical emergency, call your doctor or 911 immediately.

Torat Imecha Parsha
Parshat Vayeira: The Genes of Generosity - How to Pass on Abraham's DNA

Torat Imecha Parsha

Play Episode Listen Later Nov 4, 2025


Fundación Juan March
Acerca de la exposición Robert Rauschenberg: el uso de las imágenes

Fundación Juan March

Play Episode Listen Later Nov 3, 2025 88:25


Coloquio sobre la concepción y organización de la exposición con los comisarios de la muestra y otros invitados. La charla se divide en dos partes. En la primera, se habla sobre el proyecto expositivo, la museografía y la gráfica, haciendo hincapié en el catálogo que acompaña a la exposición. En la segunda, participan tres artistas españoles cuyo trabajo tiene conexiones con el de Robert Rauschenberg.Más información de este acto

Demystifying Genetics
When Genes Guide Care: BRCA, Rapid Testing and Real Choices. Demystifying Genetics with Mary-Anne Young (Favourite Genes BRCA1&2).

Demystifying Genetics

Play Episode Listen Later Nov 3, 2025 45:55 Transcription Available


Dr Matt Burgess talks with Mary-Anne Young about the real-world impact of genomics on healthcare and genetic counselling. They cover BRCA1/2 history, rapid testing, integration with oncology, and using polygenic risk to personalise care. The episode explores family systems and counselling techniques, ethical issues around returning research findings, workforce diversity, and practical steps to implement genomic advances in clinics. Listeners will get a concise look at how genomics is changing patient care, communication with families, and the direction of the genetic counselling profession.

Cadena SER Navarra
El abecedario en 28 imágenes en la exposición ‘Abcden…focadas' de UNED Tudela

Cadena SER Navarra

Play Episode Listen Later Nov 3, 2025 6:22


Entrevista en Hoy por Hoy Ribera con Vanessa Cañadas, del colectivo  del citado colectivo Enfocadas Zaragoza sobre la muestra podrá visitarse hasta el próximo 21 de noviembre en el patio del Palacio del Marqués de San Adrián

El Cine en la SER
Las series | Los orígenes del payaso de 'It', la adaptación de 'Cometierra' y lo nuevo del creador de 'Breaking Bad'

El Cine en la SER

Play Episode Listen Later Nov 2, 2025 18:00


El ritmo de estrenos de series es inasumible, por eso aprovechamos este episodio para repasar algunas de las últimas y ver si merecen la pena. HBO Max ya ha estrenado 'It: Bienvenidos a Derry Girl', su apuesta de terror para estos días con los inicios del payaso más diabólico. También llega a Prime Vide la adaptación de 'Cometierra', una historia sobre los desaparecidos en Argentina y la violencia. Y por último, hemos charlado con Vince Gilligan, el creador de 'Breaking Bad' regresa con una serie sobre la felicidad. Se titula 'Pluribus' y la estrena Apple TV.

SEO para Google
Imágenes que posicionan: el SEO visual de 2025 que Google, Lens e IA entienden

SEO para Google

Play Episode Listen Later Oct 31, 2025 6:32 Transcription Available


El SEO visual para Google en 2025 se sostiene en la utilidad y el contexto: una imagen no debe ser solo bonita, debe contar una idea clara y dejar respuestas a la vista. Para lograrlo, conviene subir fotos originales y nítidas, con 1–2 ángulos útiles y en contexto real, y acompañarlas de un pie que diga qué es y para quién. Junto a la imagen, añade una mini lista con medidas, colores y materiales, y si vendes, el precio y el plazo de envío. La imagen principal debe ir arriba para cargar rápido, y conviene crear una guía visual con preguntas y respuestas cortas para posicionarse por ideas, no solo por productos.Un caso práctico de una tienda de plantas ilustra el enfoque: fotos tomadas con el móvil, fondo limpio, una mano para dar escala y un pie claro con datos como “luz baja, riego cada 7 días, altura 30 cm”; además, un mini cuadro de cuidados y el precio en euros, más una guía visual de plantas para poca luz. Los resultados: más apariciones en búsquedas de imágenes y en Google Lens, mayor tiempo en la página y un incremento de visitas desde móvil. La acción clave es simple: actualiza la imagen principal de tu página más visitada, añade un pie explicativo y un bloque corto con tres datos junto a la imagen, y colócala en la posición más destacada. Si la foto no explica, no es una imagen: es un acertijo que alguien ya resolvió. ¿Listo para probarlo?Conviértete en un seguidor de este podcast: https://www.spreaker.com/podcast/seo-para-google--1693061/support.Newsletter Marketing Radical: https://marketingradical.substack.com/welcomeNewsletter Negocios con IA: https://negociosconia.substack.com/welcomeMis Libros: https://borjagiron.com/librosSysteme Gratis: https://borjagiron.com/systemeSysteme 30% dto: https://borjagiron.com/systeme30Manychat Gratis: https://borjagiron.com/manychatMetricool 30 días Gratis Plan Premium (Usa cupón BORJA30): https://borjagiron.com/metricoolNoticias Redes Sociales: https://redessocialeshoy.comNoticias IA: https://inteligenciaartificialhoy.comClub: https://triunfers.com

Empowered Patient Podcast
Significance of Regulatory RNA in Protein Production in Specific Genes with Dr. Yuri Maricich CAMP4 Therapeutics

Empowered Patient Podcast

Play Episode Listen Later Oct 31, 2025 18:46


Dr. Yuri Maricich, Chief Medical Officer at CAMP4 Therapeutics, describes regulatory RNA, a new area of biology that recognizes the role of Reg RNA in the production of proteins from specific genes. This technology is well-suited for haploinsufficient diseases such as SYNGAP1-related disorders, in which there is a lack of healthy protein and both parents carry a copy of the mutated gene. The goal is to create disease-modifying treatments that correct the underlying genetic cause rather than treating the symptoms. Yuri explains, "What was really unique about CAMP4's scientific approach is that we're focused on a whole new and emerging area of biology called regulatory RNA. And these are control elements for the expression of genes. In other words, how much protein we get from a particular gene. And there's been a lot of work in the past on how to have less protein made, particularly if it's a protein that has a mutation that causes a problem. But in medicine, there have been very few opportunities to actually increase the amount of protein, but there are many diseases that need more healthy protein." "The backdrop of CAMP4 is that there was work done just over eight years ago at the Whitehead Institute at the Massachusetts Institute of Technology in a lab by Rick Young, and he was working with a colleague at Boston Children's Hospital, Lenson, and they noticed that there was this group of so-called regRNAs. These were non-coding regions that historically have been really ignored. And as they looked and explored their function further, what they discovered was that, in fact, these regRNA elements play a critical role in controlling how much protein is produced. And so the story of CAMP4 has been to continue to understand and map different cell lines so that we could take a particular target gene and, by using tools or established medicines, for example, like antisense oligonucleotides, we could actually increase the amount of a gene's protein back up to normal." #CAMP4 #CAMP4Therapeutics #SYNGAP1 #CuresSYNGAP1 #regRNA #RegulatoryRNA camp4tx.com Download the transcript here

Empowered Patient Podcast
Significance of Regulatory RNA in Protein Production in Specific Genes with Dr. Yuri Maricich CAMP4 Therapeutics TRANSCRIPT

Empowered Patient Podcast

Play Episode Listen Later Oct 31, 2025


Dr. Yuri Maricich, Chief Medical Officer at CAMP4 Therapeutics, describes regulatory RNA, a new area of biology that recognizes the role of Reg RNA in the production of proteins from specific genes. This technology is well-suited for haploinsufficient diseases such as SYNGAP1-related disorders, in which there is a lack of healthy protein and both parents carry a copy of the mutated gene. The goal is to create disease-modifying treatments that correct the underlying genetic cause rather than treating the symptoms. Yuri explains, "What was really unique about CAMP4's scientific approach is that we're focused on a whole new and emerging area of biology called regulatory RNA. And these are control elements for the expression of genes. In other words, how much protein we get from a particular gene. And there's been a lot of work in the past on how to have less protein made, particularly if it's a protein that has a mutation that causes a problem. But in medicine, there have been very few opportunities to actually increase the amount of protein, but there are many diseases that need more healthy protein." "The backdrop of CAMP4 is that there was work done just over eight years ago at the Whitehead Institute at the Massachusetts Institute of Technology in a lab by Rick Young, and he was working with a colleague at Boston Children's Hospital, Lenson, and they noticed that there was this group of so-called regRNAs. These were non-coding regions that historically have been really ignored. And as they looked and explored their function further, what they discovered was that, in fact, these regRNA elements play a critical role in controlling how much protein is produced. And so the story of CAMP4 has been to continue to understand and map different cell lines so that we could take a particular target gene and, by using tools or established medicines, for example, like antisense oligonucleotides, we could actually increase the amount of a gene's protein back up to normal." #CAMP4 #CAMP4Therapeutics #SYNGAP1 #CuresSYNGAP1 #regRNA #RegulatoryRNA camp4tx.com Listen to the podcast here

Luis Cárdenas
Donald Trump y la IA: cómo el presidente domina la narrativa digital con imágenes creadas por inteligencia artificial

Luis Cárdenas

Play Episode Listen Later Oct 31, 2025 12:33


Durante una conversación con Luis Cárdenas en MVS Noticias, la doctora Laura Coronado, especialista en cultura digital, destacó que el mandatario “entendió perfectamente hacia dónde van las redes sociales y cómo conectar con los votantes a través de comunidades digitalesSee omnystudio.com/listener for privacy information.

Huberman Lab
Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair

Huberman Lab

Play Episode Listen Later Oct 30, 2025 39:07


In this Huberman Lab Essentials episode, my guest is Dr. David Sinclair, PhD, a professor of genetics at Harvard Medical School and a leading expert on the biology of aging. We discuss the cellular and molecular mechanisms of aging—and how specific behaviors, such as fasting, regular exercise and NAD⁺-boosting compounds like NMN, can activate the body's natural longevity pathways. This discussion highlights how lifestyle choices profoundly influence the aging process and may even slow or reverse key aspects of biological aging. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AGZ by AG1: https://drinkagz.com/huberman David: https://davidprotein.com/huberman Eight Sleep: https://eightsleep.com/huberman Timestamps (0:00) David Sinclair (0:20) Longevity, Anti-Aging, Aging as a Disease (2:27) Causes of Aging; Epigenome & Genes (4:53) CD & Scratches Analogy, DNA, Silencing & Expressing Genes (6:44) Physical Appearance & Aging (7:36) Sponsor: David (8:54) Childhood Development & Aging, Horvath Clock, Accelerate Aging (11:30) Rates of Puberty & Aging, Growth Hormone (12:37) Body Size & Longevity; Epigenetics (13:07) Fasting, Calorie Restriction & Longevity, Sirtuins, Insulin & Glucose (16:31) Tool: Skip a Meal (17:07) Longer Fasts & Autophagy, “Deep Cleanse” (18:07) Sponsor: AGZ by AG1 (19:36) Fasting, Fluids, Electrolytes (20:16) Sirtuins, Glucose, mTOR & Fasting; Leucine, Tool: Pulsing Behaviors (24:24) Breaking a Fast, Tools: Do Your Best; Transitions (27:00) Sirtuins, NAD, NMN Supplementation (29:04) Sponsor: Eight Sleep (31:10) Iron & Senescent Cells; Personalize Medicine (32:40) Tool: Blood Markers, CRP (34:50) Tool: Aerobic & Resistance Exercise (35:55) Estrogen, Fasting & Fertility; Aging & Rejuvenation (38:20) Acknowledgements Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

Divulgacion Total
Los orígenes prusianos de la educación moderna (Prussiagate continuación) - Parte 2

Divulgacion Total

Play Episode Listen Later Oct 30, 2025 19:25


Como se describió en una investigación prusiana anterior, la Universidad de Marburg, con sede en Prusia, se consideraba su escuela hermana marxista en Alemania.

El Despelote podcast
Primeras imágenes aéreas de Jamaica tras el paso del huracán Melissa - Con Rocky, Burbu y Giga #El Despelote #LaNueva94

El Despelote podcast

Play Episode Listen Later Oct 30, 2025 8:52


Lugares misteriosos
Altares, cementerios y fantasmas: Orígenes y mitos del Día de Muertos

Lugares misteriosos

Play Episode Listen Later Oct 30, 2025 12:45 Transcription Available


Cada año, México se transforma en un puente entre el mundo de los vivos y el de los muertos.En este episodio exploramos el origen, la historia y las leyendas más misteriosos que rodean al Día de Muertos, una celebración donde el tiempo se detiene, las almas regresan y el pasado susurra entre flores de cempasúchil y velas encendidas.Descubre el verdadero origen, los rituales y las leyendas que mantienen viva esta tradición eterna.

Relationship Insights with Carrie Abbott
Kindness Can Change Your Life and Your Genes!

Relationship Insights with Carrie Abbott

Play Episode Listen Later Oct 29, 2025 28:01


An intentional act of kindness, according to research and the Word of God, is literally life-changing, by God's design. How does kindness affect brain circuitry? How do we impact each other with kindness? We delve into the details…prepare to be encouraged!

Antena Historia
Historia de Irlanda: de sus orígenes a el acta de unión 1801 - Acceso anticipado - Episodio exclusivo para mecenas

Antena Historia

Play Episode Listen Later Oct 29, 2025 66:49


Agradece a este podcast tantas horas de entretenimiento y disfruta de episodios exclusivos como éste. ¡Apóyale en iVoox! En este episodio épico, desenterramos la historia de Irlanda, una tierra cuya identidad está forjada tanto en la magia de sus mitos como en la sangre de sus batallas. Es un recorrido de dos milenios que nos lleva desde los Altos Reyes hasta el dramático acto que disolvió su soberanía: el Acta de Unión de 1801. ---------------------------------------------------------------------------------------- 🎧 Antena Historia te regala 30 días PREMIUM Disfruta de todo el contenido sin interrupciones y con ventajas exclusivas en iVoox: 👉 https://www.ivoox.com/premium?affiliate-code=b4688a50868967db9ca413741a54cea5 📻 Producción y realización: Antonio Cruz 🎙️ Edición: Antena Historia 📡 Antena Historia forma parte del sello iVoox Originals 🌐 Visita nuestra web: https://antenahistoria.com 📺 YouTube: Podcast Antena Historia 📧 Correo: antenahistoria@gmail.com 📘 Facebook: Antena Historia Podcast 🐦 Twitter: @AntenaHistoria 💬 Telegram: https://t.me/foroantenahistoria 💰 Apoya el proyecto: Donaciones en PayPal 📢 ¿Quieres anunciarte en Antena Historia? Ofrecemos menciones, cuñas personalizadas y programas a medida. Más información en 👉 Antena Historia – AdVoices Escucha el episodio completo en la app de iVoox, o descubre todo el catálogo de iVoox Originals

JCO Precision Oncology Conversations
Somatic Mutations of Colorectal Cancer by Birth Cohort

JCO Precision Oncology Conversations

Play Episode Listen Later Oct 29, 2025 7:33


In this episode of JCO PO Article Insights, host Dr. Jiasen He summarizes the article, "Somatic Mutation Profiles of Colorectal Cancer by Birth Cohort" by Gilad, et al published October 11, 2025. TRANSCRIPT Jiasen He: Hello, and welcome to the JCO Precision Oncology Article Insights. I am your host, Jiasen He, and today, we will be discussing the JCO Precision Oncology article, "Somatic Mutation Profiles of Colorectal Cancer by Birth Cohort," by Dr. Gilad and colleagues. Early-onset colorectal cancer is defined as colorectal cancer diagnosed before the age of 50. Several reports have suggested that early-onset colorectal cancer has unique characteristics. Compared with late-onset colorectal cancer, early-onset colorectal cancer cases are more commonly found in the distal colon or rectum, tend to be diagnosed at more advanced stages, and may display unfavorable histologic features. Although the overall incidence of colorectal cancer has declined in recent decades, the incidence of early-onset colorectal cancer continues to rise. This increase appears to be driven by birth cohort effects. The reasons behind this rise remain unclear but are likely multifactorial, involving changes in demographics, diet, lifestyle, environmental exposures, and genetic predisposition. At the same time, studies have shown conflicting results regarding whether there are differences in the mutation profiles between early-onset and late-onset colorectal cancer. Therefore, it is crucial to explore whether colorectal cancer somatic mutational landscape differs across birth cohorts, as this could provide important insight into generational shifts in colorectal cancer incidence. To address this question, the authors conducted a retrospective study to characterize the mutation spectrum of colorectal cancer across different birth cohorts. Consecutive colorectal cancer patients who underwent somatic next-generation sequencing at the University of Chicago pathology laboratory between 2015 and 2022 were retrospectively identified. Tumors were tested for 154 to 168 genes and categorized as either microsatellite stable or high according to established thresholds. Patients with hereditary cancer syndromes or inflammatory bowel disease were excluded. Participants were then grouped into birth cohorts by decades, as well as into two major groups: those born before 1960 and after 1960. Genes that were identified in at least 5% of the sample were selected and grouped into 10 canonical cancer signaling pathways. These genes and pathways were then included in the analysis to explore their association with colorectal cancer across different birth cohorts and age groups. A total of 369 patients were included in the study, with a median birth year of 1955 and a median age at colorectal cancer diagnosis of 62.9 years. 5.4% were identified as having microsatellite-high tumors. The median tumor mutational burden was 5 mutations per megabase for microsatellite-stable tumors and 57.7 mutations per megabase for microsatellite-high tumors. Patients with microsatellite-high tumors tended to have earlier birth years and were diagnosed at an older age. However, after adjusting for potential confounders, neither birth year nor age remained statistically significant. Similarly, after controlling for confounders, no significant associations were observed between birth year or age and mutation burden. In this cohort, APC, TP53, and KRAS were the most frequently mutated genes. No statistically significant differences in the prevalence of gene mutations were observed across birth cohorts. Correspondingly, the most affected signaling pathways were the Wnt, TP53, and (RTK)/RAS pathways. Similar to the gene-level finding, no significant differences in the prevalence of these pathways were identified among birth cohorts. When examining patients born before and after 1960, the authors found that the older birth cohorts were diagnosed at an older age and had higher tumor mutational burden. However, no significant differences were observed in any of the genes or pathways analyzed. Among microsatellite-stable tumors, 18.3% were classified as early-onset colorectal cancer, while 81.1% were late-onset colorectal cancer. Consistent with previous reports, early-onset colorectal cancers in this cohort were more likely to be left-sided and more common among more recent birth cohorts. However, no significant differences were identified in any of the examined genes or pathways when comparing early-onset to late-onset colorectal cancer. In this cohort, a higher prevalence of early-onset colorectal cancer was observed among more recent birth cohorts, consistent with previous reports. Still, no distinct mutational signature was identified between the early and late birth cohorts. The authors proposed that the lack of distinct mutational profile by age or birth cohort may be due to the limited number of key molecular pathways driving colorectal cancer. Although environmental exposures likely differ across generations, the downstream effects may have converged on similar biological mechanisms, leading to comparable somatic mutations across cohorts. Alternately, they proposed that the observed birth cohort differences in colorectal incidence may be driven by distinct mutation signatures, epigenetic alterations, or changes in the immune microenvironment rather than variations in canonical gene mutations. As the authors noted, given the retrospective nature of this study, its modest sample size, and the predominance of advanced-stage tumors, larger prospective studies are needed to validate these findings. In summary, this study found no significant differences in the mutational landscape of colorectal cancer across birth cohorts or age groups. The authors proposed that the generational shift in colorectal cancer incidence is unlikely to be driven by changes in the underlying tumor genomics. However, larger prospective studies are needed to validate these findings. Thank you for tuning in to JCO Precision Oncology Article Insights. Do not forget to subscribe and join us next time as we explore more groundbreaking research shaping the future of oncology. The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.

Daily Easy Spanish
Las imágenes que muestran la destrucción que dejó el huracán Melissa en Jamaica

Daily Easy Spanish

Play Episode Listen Later Oct 29, 2025 11:41


Melissa, el mayor huracán en la historia de Jamaica, dejó escenas de devastación con viviendas sin tejados, árboles derribados, autos volcados y familias que lo han perdido todo.

UNPILLED Podcast
Fall Health Essentials: Immunity Boosting Tips and Tools

UNPILLED Podcast

Play Episode Listen Later Oct 28, 2025 52:19


Are you ready to stay healthy this fall season? Join our expert hosts, Dr. Lara Varden and Dr. Krista Kostroman, as we dive into staying healthy this fall season. This session will share essential tips and practical tools to enhance immunity, focusing on nutrition, lifestyle adjustments, and effective supplements. Learn how to strengthen your family's immune system with easy-to-implement strategies that ensure you stay healthy and thrive in this fall.______________________________________________________Keep yourself up to date on The DNA Talks Podcast! Follow our socials below:The DNA Talks Podcast Instagram: @dnatalkspodcastThe DNA Company Instagram: @thednacoThe DNA Company's Official Tiktok Account: @thednaco3______________________________________________________Medical Disclaimer: The information provided in this communication is for general informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read here. If you think you may have a medical emergency, call your doctor or 911 immediately.

One in Six Billion
Special Episode 8: Steve Chapman, Andrew Hattersley and Maggie Shepherd. Final reflections on making the One in Six billion podcast.

One in Six Billion

Play Episode Listen Later Oct 28, 2025 25:29


In the final episode of the One in Six Billion podcast Andrew and Maggie reflect with producer Steve Chapman on the fun they have had making 51 podcasts with 70 guests in the past 2 years.Send us a text

Health Shotzz by Ryan Fernando
The Only Skincare Video You Need to Watch ft Doctor Chytra Anand | ‪S3 Ep 17

Health Shotzz by Ryan Fernando

Play Episode Listen Later Oct 27, 2025 116:04


Confused about what skincare really suits you? Wondering if Korean skincare is worth the hype or how important sunscreen truly is?All your skincare questions — answered!

Demystifying Genetics
When Genes Meet Heart: Inside Cardiac Genomics. Demystifying Genetics with Jodie Ingles (Favourite Gene: MYH7)

Demystifying Genetics

Play Episode Listen Later Oct 27, 2025 45:12 Transcription Available


Host Matt Burgess talks with Dr Jodie Ingles, a leading cardiac genetic counsellor and researcher, about inherited heart conditions, supporting families after sudden cardiac events, and translating genomic discoveries into clinical care. The episode covers variant classification, health equity, the evolving role of genetic counsellors, and the importance of mentorship and practical changes needed to bring genomic testing into everyday practice.

Aging-US
TRF1 Protein Loss Reduces Fat and Improves Metabolic Health in Mice Without Shortening Telomeres

Aging-US

Play Episode Listen Later Oct 27, 2025 3:05


BUFFALO, NY — October 27, 2025 — A new #research paper was #published in Volume 17, Issue 9 of Aging-US on September 17, 2025, titled “Depletion of the TRF1 telomere-binding protein leads to leaner mice with altered metabolic profiles.” In this study led by first author Jessica Louzame Ruano and corresponding author Maria A. Blasco from the Spanish National Cancer Centre (CNIO), researchers investigated the role of TRF1, a protein known for protecting telomeres, in regulating whole-body metabolism. The results suggest that TRF1 influences metabolic health through mechanisms unrelated to its known function in telomere maintenance. Obesity and metabolic disorders are major health concerns, especially as people age. To explore TRF1's role beyond telomere protection, the research team studied both normal mice and genetically modified mice that lacked TRF1. Mice without TRF1 remained leaner over time, resisted fat accumulation, and showed healthier blood sugar and insulin levels compared to normal mice. Importantly, these benefits occurred without any detectable shortening of telomeres. The leaner body composition in TRF1-deficient mice was not due to reduced food intake or increased physical activity. Instead, the fat loss appeared to result from biological changes in how energy was processed and stored. Male mice without TRF1 gained less weight and had lower LDL cholesterol levels, even on a high-fat diet. Female mice showed milder effects, reflecting known sex-based differences in susceptibility to diet-induced obesity. This highlights the importance of including both sexes in metabolic research. “Major metabolic pathways related with energy production and regulation of metabolism homeostasis were also found downregulated in Trf1-deficient mice.” Gene expression analysis in the liver revealed shifts in several key pathways. Genes related to fat production, energy generation, and muscle growth were downregulated, while genes linked to inflammation and cholesterol synthesis were upregulated. The mice also showed signs of higher energy expenditure and a shift from using fat to protein as an energy source, possibly due to their reduced fat reserves. However, some older mice developed mild liver stress, including fibrosis and DNA damage, suggesting a possible long-term trade-off. Overall, this study expands the understanding of how telomere-related proteins influence more than just cellular aging. By identifying a connection between TRF1 and metabolism, the research opens new possibilities for targeting TRF1 or its pathways to address obesity and related conditions. Still, further studies are needed to clarify how TRF1 affects fat development and whether similar effects occur in humans. DOI - https://doi.org/10.18632/aging.206320 Corresponding author - Maria A. Blasco — mblasco@cnio.es Abstract video - https://www.youtube.com/watch?v=7AG3TBgDZIw Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206320 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, Trf1, metabolism, leaner, fat, telomeres To learn more about the journal, visit https://www.Aging-US.com​​ and connect with us on social media at: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Bluesky - https://bsky.app/profile/aging-us.bsky.social Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

Salud de por vida
Comprensión de las imágenes: desde la primera mamografía hasta el seguimiento con el Dra. Adrian Miller del Peeples Cancer Institute del Hamilton Medical Center

Salud de por vida

Play Episode Listen Later Oct 26, 2025 13:56


El Dra. Adrian Miller es radiólogo certificado y con especialización en imágenes mamarias en el Instituto Oncológico Peeples del Centro Médico Hamilton en Dalton, Georgia. Para obtener más información sobre el Instituto Oncológico Peeples, llame al 844-PCI-HOPE o visite VitruvianHealth.com/cancer.Este programa no pretende diagnosticar ni tratar enfermedades ni reemplazar la atención médica profesional. Si tiene algún problema de salud, consulte a su profesional de la salud.

Salud de por vida
Detección de alto riesgo, pruebas genéticas y experiencia en imágenes mamarias con el Dr. Adrian Miller del Peeples Cancer Institute del Hamilton Medical Center

Salud de por vida

Play Episode Listen Later Oct 26, 2025 15:34


El Dra. Adrian Miller es radiólogo certificado y con especialización en imágenes mamarias en el Instituto Oncológico Peeples del Centro Médico Hamilton en Dalton, Georgia. Para obtener más información sobre el Instituto Oncológico Peeples, llame al 844-PCI-HOPE o visite VitruvianHealth.com/cancer.Este programa no pretende diagnosticar ni tratar enfermedades ni reemplazar la atención médica profesional. Si tiene algún problema de salud, consulte a su profesional de la salud.

A vivir que son dos días
Corresponsales | La gorra de Trump, la motosierra de Milei y el Peugeot de Sánchez: cuando las imágenes se hacen política

A vivir que son dos días

Play Episode Listen Later Oct 25, 2025 43:57


Hay un hilo conductor entre el uniforme negro de Meloni, el chándal tricolor de Maduro, la gorra roja de Trump, la ruta en el Peugeot de Pedro Sánchez o la mesa gigante en la que Putin se sentó con Macron en el Kremlin… y lo ha encontrado Toni Aira, doctor en Comunicación Social y Política y director del máster en Comunicación Política e Institucional de la Universitat Pompeu Fabra, autor del ensayo 'Mitólogos. El arte de seducir a las masas'.

News in Easy Spanish - Hola Qué Pasa
Niña gana contra enfermedad rara con tratamiento de genes

News in Easy Spanish - Hola Qué Pasa

Play Episode Listen Later Oct 25, 2025 3:36


Cuando Eliana tenía solo dos meses, se enfermó con una tos que no se iba. Después de más pruebas, los doctores encontraron algo muy grave – tenía una enfermedad rara llamada SCID que significa que . Los niños con SCID no tienen sistemas de defensa

The Wellness Restoration Project
Ep 3 Partnering With Your Genes - the Stress, Hormone, Genetics Loop

The Wellness Restoration Project

Play Episode Listen Later Oct 24, 2025 14:11


Episode DescriptionWhat if detox wasn't about deprivation, but about bringing your body back into flow?In this episode, Shelley Swapp blends Traditional Chinese Medicine philosophy with cutting-edge nutrigenomics to reveal how your body's natural detox pathways influence hormones, metabolism, and energy. You'll learn why restoring gentle flow—rather than forcing a cleanse—is the key to long-term balance.Shelley explains how genes like NRF2, GSTM1, GSTT1, GCLM, and COMT shape your ability to clear hormones and toxins, and how everyday foods, herbs, and joyful practices can switch those genes on again. From the “savings-account” power of glutathione to the hormone-balancing effects of sulforaphane from broccoli sprouts, this episode turns complex biochemistry into everyday wisdom.“Your genes may show where the river narrows, but your lifestyle is the water itself—bringing life back into those channels, one small, consistent ripple at a time.”

SEO para Google
Domina la Búsqueda Visual en 2025: Tamaño, uso y compatibilidad en tus imágenes

SEO para Google

Play Episode Listen Later Oct 24, 2025 10:45 Transcription Available


En este episodio se revela cómo la búsqueda visual está redefiniendo la forma en que los usuarios encuentran productos en 2025. La clave no es solo aparecer, sino mostrar en la imagen lo que el cerebro quiere ver: tamaño, uso y compatibilidad. Te proponen un plan práctico para empezar hoy: una imagen principal clara y amplia, una segunda foto con las medidas visibles, una imagen de uso real, etiquetas de compatibilidad en la imagen, un texto breve que describa lo que se ve y un vídeo corto que explique el punto clave. Todo ello ayuda a que el usuario sepa, sin esfuerzo, qué es y si le sirve.Para ilustrarlo, cuentan una historia real de una ferretería en Zaragoza que dio un giro resolviendo la duda visual: tres imágenes claras (una en fondo blanco, otra con una moneda para medir, otra mostrando el tornillo ya instalado) y un vídeo operativo, manteniendo consistentes nombres y medidas en todas las fichas. El mensaje clave es simple: pregunta cada día si tu producto podría decidirse solo mirando la imagen; si la respuesta es no, añade medidas, contexto y compatibilidad y prueba un cambio a la vez. Si te pica la curiosidad, escucha el episodio completo y aplica estas ideas para empezar a aparecer en búsquedas visuales mañana.Conviértete en un seguidor de este podcast: https://www.spreaker.com/podcast/seo-para-google--1693061/support.Newsletter Marketing Radical: https://marketingradical.substack.com/welcomeNewsletter Negocios con IA: https://negociosconia.substack.com/welcomeMis Libros: https://borjagiron.com/librosSysteme Gratis: https://borjagiron.com/systemeSysteme 30% dto: https://borjagiron.com/systeme30Manychat Gratis: https://borjagiron.com/manychatMetricool 30 días Gratis Plan Premium (Usa cupón BORJA30): https://borjagiron.com/metricoolNoticias Redes Sociales: https://redessocialeshoy.comNoticias IA: https://inteligenciaartificialhoy.comClub: https://triunfers.com

The Art of Being Well
Pain Relief, Magnesium Timing, Methylation Genes & The “Switch Witch” Parenting Debate | Ask Me Anything

The Art of Being Well

Play Episode Listen Later Oct 23, 2025 60:44


In this Ask Me Anything episode, Dr. Will Cole and his telehealth team - Andrea and Emily - tackle your biggest wellness questions. From the latest autism research linked to acetaminophen and pregnancy, to safe natural alternatives for pain relief, they break down what's science and what's spin. They also discuss Dr. Cole's Longevity RX Mag 18 supplement, the role of magnesium and vitamin D synergy, and how to manage complex genetic issues like the CBS mutation. The team covers HHS's new vaccine recommendations and explores the viral “Switch Witch” parenting trend - helping families navigate food and wellness with balance, not fear. For all links mentioned in this episode, visit www.drwillcole.com/podcast.Please note that this episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct or indirect financial interest in products or services referred to in this episode.Sponsors:Right now, they're offering my listeners 50% off at makespaceandtime.com/willcole or on Amazon with the code WILLCOLE50.Text ABW to 64000 to get twenty percent off all IQBAR products, plus FREE shipping. Message and data rates may apply.Go to Quince.com/willcole for free shipping on your order and three hundred and sixty-five-day returns. Now available in Canada! For a limited time only, our listeners are getting a HUGE discount on the iRestore Elite when you use code WILLCOLE at iRestore.com - PLEASE support our show and tell them we sent you.Visit gruns.co and use code WILLCOLE at checkout for up to 52% off your first order.Produced by Dear Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Divulgacion Total
Los orígenes prusianos de la educación moderna (Prussiagate continuación) - Parte 1

Divulgacion Total

Play Episode Listen Later Oct 23, 2025 15:10


La educación moderna parece haberse descarrilado. Muchos de nosotros éramos al menos algo conscientes de las opiniones políticas de izquierda sobre el Complejo Industrial Educativo. Cuando se impuso la cuarentena en todo el mundo, los padres comenzaron a darse cuenta lo que sus hijos estaban aprendiendo.

Hora 25
Las 20 de Hora 25 | Una nueva mujer andaluza denuncia que una de las imágenes de su mamografía ha cambiado

Hora 25

Play Episode Listen Later Oct 23, 2025 21:48


Las noticias que debes conocer esta tarde, con Isabel Villar

Mission Matters Podcast with Adam Torres
Your Genes, Your Game Plan: SNiP Nutrigenomics with Kim Ressler

Mission Matters Podcast with Adam Torres

Play Episode Listen Later Oct 22, 2025 13:53


On Mission Matters, Adam Torres interviews Kim Ressler, Founder & CEO of SNiP Nutrigenomics, about using genetic testing to reveal actionable pathways (methylation, detox, inflammation, immune, heart health) and create personalized nutrition that targets root causes. Kim's mission is to simplify genetics and bring nutrigenomics to consumers, clinics, and employers for measurable, lasting health gains. Follow Adam on Instagram at https://www.instagram.com/askadamtorres/ for up to date information on book releases and tour schedule. Apply to be a guest on our podcast: https://missionmatters.lpages.co/podcastguest/ Visit our website: https://missionmatters.com/ More FREE content from Mission Matters here: https://linktr.ee/missionmattersmedia Learn more about your ad choices. Visit podcastchoices.com/adchoices

Effective Fitness for Women: Fat Loss & Muscle Gain for Fitness Beginners
162| [Fixed audio] Metabolism, Hormones, or Just Bad Genes? How To Figure Out What's Stalling Your Weight Loss

Effective Fitness for Women: Fat Loss & Muscle Gain for Fitness Beginners

Play Episode Listen Later Oct 22, 2025 15:12


If you've been doing everything right but the scale just won't move, this episode is for you. I'm breaking down how to figure out what's really stalling your progress — whether it's your lifestyle, metabolism, or hormones — and how to find your “limiting reactant” so you can finally move forward. The Fat Loss Formula for Moms Book a Free Discovery Call

Confidence Through Health
Using Our Genes to Upgrade Our Health w/ Kyler Ockey

Confidence Through Health

Play Episode Listen Later Oct 22, 2025 44:31


The journey to a healthier body can sometimes be a struggle. Some foods help, some don't. Certain exercises are supposed to be good but don't show everyone the same rewards. That's where our genes could unlock the path to personalized health.Kyler Ockey shares some of the breakthroughs that Shed is working on to help people individualize and personalize their health journey. Turns out our genes play an important role in how food, exercise, and our environment affect our physical body. Without knowing how to optimize our genes, we could be doing "everything right" and not get the results we want. Kyler Ockey is the Chief Strategy & Product Officer at Shed, a leader in science-backed wellness solutions. Shed created Genetic Testing Kits, designed to help individuals understand how their bodies respond to nutrition, fitness, sleep, stress, and more — and make choices that work with their biology, not against it. Available in four targeted options — Total Wellness, Nutrition + Fitness, Nutrition, and Fitness — the kits provide personalized insights and actionable recommendations for fueling smarter, training effectively, and supporting long-term health. Follow Shed on Instagram @tryshed Visit ConfidenceThroughHealth.com to find discounts to some of our favorite products.Follow me via All In Health and Wellness on Facebook or Instagram.Find my books on Amazon: No More Sugar Coating: Finding Your Happiness in a Crowded World and Confidence Through Health: Live the Healthy Lifestyle God DesignedProduction credit: Social Media Cowboys

Comedy Trap House
Is It your Jeans or your Genes?

Comedy Trap House

Play Episode Listen Later Oct 21, 2025 56:18


What up yall! In this episode we recap a wild night filled with Baseball, phone calls, and Strip clubs. Also, Romes Journey with jeans lol tune in!  This episode is sponsored by BetterHelp. Give online therapy a try at https://www.betterhelp.com/unapod and get on your way to being your best self To watch the podcast on YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@DormtainmentTV⁠⁠⁠ Follow Rome: ⁠⁠⁠@iromealot⁠⁠⁠ Follow Cameron: ⁠⁠⁠@camfromdt⁠ Learn more about your ad choices. Visit podcastchoices.com/adchoices

Today's RDH Dental Hygiene Podcast
Audio Article: Research Finds a High Abundance of Previously Unknown Antibiotic-Resistant Genes in Bacteria

Today's RDH Dental Hygiene Podcast

Play Episode Listen Later Oct 21, 2025 5:42


Research Finds a High Abundance of Previously Unknown Antibiotic-Resistant Genes in BacteriaBy Today's RDH ResearchOriginal article published on Today's RDH: https://www.todaysrdh.com/research-finds-a-high-abundance-of-previously-unknown-antibiotic-resistant-genes-in-bacteria/Need CE? Start earning CE credits today at https://rdh.tv/ce Get daily dental hygiene articles at https://www.todaysrdh.com Follow Today's RDH on Facebook: https://www.facebook.com/TodaysRDH/Follow Kara RDH on Facebook: https://www.facebook.com/DentalHygieneKaraRDH/Follow Kara RDH on Instagram: https://www.instagram.com/kara_rdh/

Good Day Health
Cardiac Complications On the Rise In Pregnant Women

Good Day Health

Play Episode Listen Later Oct 21, 2025 33:09 Transcription Available


On today's Good Day Health Show - ON DEMAND…Host Doug Stephan and Dr. Ken Kronhaus of Lake Cardiology (352-735-1400) cover a number of topics affecting our health. First up, Doug and Dr. Ken discuss the biggest news stories in the medical world, starting with the good news of a gene-editing technique that could correct a mutation responsible for a certain type of inherited heart disease. This is a significant step forward that could offer a potential targeted correction of genetic faults. In other heart news, and not good news, there are more heart complications in pregnant women — which could be related to higher rates of obesity, women getting pregnant at an older age, and a steady increase in heart-related health problems during pregnancy. Moving on, a discussion on the growing preference of marijuana use over alcohol, and whether or not either is OK in what kind of moderation. In the good news department, there's a new blood test for cancer detection in your head and neck, a successful pig liver transplant, and AI-powered wearable devices could be the future of medicine for Parkinson's patients to offer better treatment decisions. Moving on, research shows young students who spend excessive time on social media perform worse on tests in subjects like reading, memory and language.Then, a focus on the antimicrobial resistance with some bacterial infections becoming drug-resistant, turning routine infections into deadly instances. Website: GoodDayHealthrShow.com Social Media: @GoodDayNetworks

Balls Out with Ben Glaze and Brett Haze
Episode 343: Good Genes

Balls Out with Ben Glaze and Brett Haze

Play Episode Listen Later Oct 20, 2025 54:04


An OnlyFans body paint stunt, ghost hunting at a casino, alien DNA, and more.

The Human Upgrade with Dave Asprey
These Plants Turn On 1,100 Healing Genes In 24 Hours (Ancient Biohacks) : 1346

The Human Upgrade with Dave Asprey

Play Episode Listen Later Oct 16, 2025 56:52


Most people try to “heal” their brain with supplements, mindset, or meditation—but this episode reveals the deeper protocol to actually grow a new brain, reverse stress damage, activate 1,100 healing genes, and unlock higher human performance at any age. You'll learn how neuroplasticity, mitochondria repair, plant-based NRF2 activators, and energetic practices work together to rebuild the brain and extend longevity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Alberto Villoldo, Ph.D.—medical anthropologist, neuroscientist, energy medicine pioneer, and founder of The Four Winds Society, the gold-standard school for modern shamans. He has spent 25+ years studying Amazonian and Andean healing traditions, led the Biological Self-Regulation Lab at San Francisco State University to explore psychosomatic medicine, and authored more than 25 bestselling books on neuroscience, functional medicine, and energy healing. Few people on earth bridge ancient biohacking and modern brain science at this level. He also reveals the forms of nicotine that are safest (spoiler: it's not vapes or cigarettes), how nicotine works at the receptor level, and what the science says about long-term health effects. This episode blends functional medicine, brain optimization, and biohacking into one powerful, myth-busting breakdown. You'll learn: • How to grow a new brain every 22 days using neuroplasticity and mitochondria support • Why plant medicines and NRF2 activators can turn on 1,100 healing genes in 24 hours • The surprising link between nootropics, psychedelics, serotonin, and endogenous DMT • How mindset, belief systems, and placebo/nocebo shape immune function and metabolism • Why RFK's chronic disease warning connects to viral evolution and immune collapse • The real reason carnivore diets work—and when they fail without gut repair • Peptides, GLP-1 agonists, and the future of functional medicine hacking • Why most people sabotage themselves and how to stop fighting your own biology This is essential listening for anyone serious about biohacking, human performance, and longevity, and for those who want to understand how functional biology and mitochondrial science are redefining recovery, energy, and aging. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: NRF2 activation, Neurogenesis and hippocampus repair, Plant-based epigenetic triggers, Psychosomatic health, Serotonin to DMT conversion, Pineal gland methylation, Parasites and brain inflammation, Viral-driven evolution, GLP-1 agonists and longevity, Psilocybin lifespan extension, Autophagy and brain cleanup, Energetic medicine training, Functional peptides, BPC-157, Breathwork and CO2 tolerance, mTOR cycling, Cold exposure and dopamine, Mindset-driven immune function Thank you to our sponsors! • EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off. • Essentia | Go to https://myessentia.com/dave and use code DAVE for $100 off The Dave Asprey Upgrade. • Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. • fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Resources: • Learn more from Alberto at: www.thefourwinds.com and www.albertovilloldo.net • Buy the book ‘Grow A New Brain': https://a.co/d/5lVhrVy • Business of Biohacking | Register to attend October 20-23 in Austin, TX https://businessofbiohacking.com/ • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:25 — Introduction & Ayahuasca Story 3:15 — Shamanism Beyond Plant Medicine 6:53 — Losing Your Mind to Evolve 10:45 — The 22-Day New Brain Cycle 12:53 — Plant Communication & Direct Knowing 15:35 — Parasites, Liver Failure & Brain Damage 20:25 — Remote Healing & CIA Research 22:40 — Tryptophan, Turkey Farmers & Brain Chemistry 25:19 — Viruses as Evolutionary Drivers 30:30 — Psilocybin & Life Extension 35:25 — Healing with Mindset + Biology 38:52 — Spirit, Purpose & Growing Gods 43:49 — Plants, Protein & mTOR 49:07 — Training the Four Brains 51:16 — Cold Exposure: Pain vs Suffering 54:40 — Who Am I? Living the Question 55:25 — Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Healthy Mind, Healthy Life
Lifestyle Secrets to Longevity, Wellness & Fulfillment at 83 with Michael Dorfman

Healthy Mind, Healthy Life

Play Episode Listen Later Oct 14, 2025 31:46


At 83, certified health & nutrition life coach and longevity advocate Michael Dorfman explains why aging well is less about luck and more about daily, repeatable choices—whole-food plant-based eating, stress reduction, movement, brain challenges, intermittent fasting, and hot/cold exposure. We unpack how habits compound over decades, why chronic disease often starts early, and how to design a meaningful life at any age.   About the guest  : Michael Dorfman is a certified health & nutrition life coach, investigative author, and longevity advocate. Vegetarian since 1976 and whole-food plant-based since 2008, he earned Plant-Based Nutrition certification from Cornell (2019). His work—including The Thriving Vegan and The Longevity Wellness Revolution—translates decades of study into actionable steps for vibrant aging. He lives in Mexico and publishes weekly articles on Substack.   Key takeaways: Longevity isn't fate; it's shaped by daily lifestyle choices more than genetics. Whole-food, plant-based nutrition is Michael's non-negotiable foundation for vitality. Ultra-processed foods (now a large share of global diets) drive metabolic and inflammatory burden—cut them first. Build resilience by challenging body and brain: strength work, new skills, non-dominant-hand practice, board games, pickleball. Intermittent fasting and hot/cold exposure can fortify energy, focus, and recovery when used sensibly. Stress management is longevity-critical—relationships, work fear, and news cycles compound wear and tear. Chronic disease often begins decades earlier; start small now (one meal/one habit at a time). Habits change through repetition and identity shift—see yourself as a healthy person and act accordingly. Genes may set a baseline, but environment and behavior influence expression; don't surrender agency. For those with existing conditions, incremental improvements still matter—focus on controllable inputs and coordinated care.   Medical Disclaimer:This conversation is for educational and informational purposes only and is not medical advice. It is not a substitute for diagnosis, treatment, or professional guidance from a qualified healthcare provider. Do not start, stop, or change any medication, diet, exercise, or supplement based on this episode without consulting your physician or licensed healthcare professional—especially if you are pregnant, nursing, have a medical condition, or are taking prescriptions.Any references to practices such as meditation, breathwork, bioenergetic/digital muscle testing, trackers, or apps reflect personal experiences and opinions; they do not replace evidence-based medical care. Healthy Mind, Healthy Life and Healthy Mind By Avik™ do not endorse specific products, services, or claims mentioned by guests. If you believe you may be experiencing a medical emergency, call your local emergency number immediately.   How to connect with the guest   Website: longevitywellnessrevolution.com/Substack: Find newsletter signup via Michael's website (weekly health and longevity articles)Coaching & Book Updates: Via website newsletter   Want to be a guest on Healthy Mind, Healthy Life? DM on PM - Send me a message on PodMatch DM Me Here: https://www.podmatch.com/hostdetailpreview/avik   Disclaimer: This video is for educational and informational purposes only. The views expressed are the personal opinions of the guest and do not reflect the views of the host or Healthy Mind By Avik™️. We do not intend to harm, defame, or discredit any person, organization, brand, product, country, or profession mentioned. All third-party media used remain the property of their respective owners and are used under fair use for informational purposes. By watching, you acknowledge and accept this disclaimer.   Healthy Mind By Avik™️ is a global platform redefining mental health as a necessity, not a luxury. Born during the pandemic, it's become a sanctuary for healing, growth, and mindful living. Hosted by Avik Chakraborty—storyteller, survivor, wellness advocate—this channel shares powerful podcasts and soul-nurturing conversations on:• Mental Health & Emotional Well-being• Mindfulness & Spiritual Growth• Holistic Healing & Conscious Living• Trauma Recovery & Self-Empowerment With over 4,400+ episodes and 168.4K+ global listeners, join us as we unite voices, break stigma, and build a world where every story matters.

HistoCast
HistoCast 325 - Orígenes de Colón

HistoCast

Play Episode Listen Later Oct 13, 2025 258:58


Esto es HistoCast. No es Esparta pero casi. Vamos con uno de los temas más discutidos por historiadores, científicos y políticos ¿De dónde era Cristóbal Colón? Nos metemos en el charco con Gregorio Garulo (@gg_goyo89651) junto a @goyix_salduero.Secciones Historia: - El mundo en el que vivió - 10:38 - Vida conocida de Colón - 1:06:28 - Historiografía - 1:53:33 - Teorías - 3:05:45 - Conclusión - 3:57:31 - Bibliografía - 4:11:56