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Host: Denise M. Dupras, M.D., Ph.D. Guest: Jewel J. Samadder, M.D., Gastroenterologist and Professor, Mayo Clinic In this episode of Mayo Clinic Talks, Dr. Denise Dupras interviews Dr. Jewel Samadder about colon cancer, with a focus on how genetics and family history influence cancer risk and screening strategies. Dr. Samadder emphasizes empowering primary care providers to identify patients who may benefit from genetic evaluation and early colonoscopy. He encourages clinicians to take thorough family histories and use them to guide screening strategies, helping catch cancer early — or prevent it entirely. Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts
The FIT Collective Genetic Insights Series – Episode 2Unlock the Secrets of Your Hunger Genetics and Eating Habits In this fascinating episode, Dr. Ali Novitsky, Obesity Medicine Expert and Fitness Guru, explores the powerful role genetics play in shaping our appetite, eating behaviors, and how we experience fullness (satiety). Drawing from science and personal experience, she breaks down how certain genes influence appetite, body composition, and emotional eating — and how understanding your genetic blueprint can empower you to make personalized, sustainable health choices.
Danilo Gómez nos habla sobre la cromatografía, una fascinante herramienta al alcance de todos. Descubre cómo la cromatografía revela la salud del suelo, impulsa la agricultura sostenible y trasciende a otros campos. Con la pasión y conocimientos de Danilo, este episodio desglosa los orígenes y aplicaciones prácticas de esta técnica de ciencia ciudadana.¡Activa tu membresía hoy!: www.radiosemilla.com/membresia Proyecto aliado: La Enmienda (Argentina) 40% de descuento para miembros en el curso online La Vida del Suelo, visita https://laenmienda.com/cursoNotas del episodio:TIerra Croma: https://www.instagram.com/tierracroma----------------Escucha Radio Semilla en:Spotify: https://open.spotify.com/show/7r8Nb90iI52NzP7dPTHrbw?si=qOncz7SZR16oLFSYeue6iwYoutube: https://www.youtube.com/playlist?list=PLIk2jCydde9el3SckTVwVJrZuOEt9JIZtRedes:instagram.com/radiosemillapodcastx.com/semilla_radiofacebook.com/radiosemillapodcast
My guest is Dr. Melissa Ilardo, Ph.D., professor of biomedical informatics at the University of Utah. We discuss the interplay between genes and behaviors, including how certain behaviors can improve resilience by changing gene and organ function, as well as natural selection events happening in humans today. We also discuss the immune system–related reasons people find the smells of potential mates attractive—or not. We explore how physical and psychological traits are passed from one generation to the next, and the specific behaviors that can influence gene expression to improve health and performance. Melissa explains her lab's pioneering research on breath-hold training and how activation of the dive reflex through breath holding can significantly improve oxygen availability by changing spleen size and function. We also delve into the medical uses and ethics of gene editing to cure disease in both babies and adults. For those interested in genes and inheritance, human performance, immune system function, and natural selection, this episode illustrates the remarkable interplay between human nature and nurture. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Joovv: https://joovv.com/huberman Eight Sleep: https://eightsleep.com/huberman LMNT: https://drinklmnt.com/huberman Function: https://functionhealth.com/huberman Timestamps 00:00:00 Melissa Ilardo 00:02:35 Nature vs Nurture, Gene Expression, Eye Color 00:07:06 Sponsors: Joovv & Eight Sleep 00:10:24 Epigenetics, Trauma, Mutations; Hybrid Vigor, Mate Attraction 00:15:47 Globalization; Homo Sapiens, Mating & Evolution; Mutations 00:25:28 Sea Nomads, Bajau & Moken Groups; Free Diving, Dangers & Gasp Reflex 00:32:52 Cultural Traditions, Free Diving & Families; Fishing 00:35:36 Mammalian Dive Reflex, Oxygen, Spleen, Cold Water & Face; Exercise 00:42:43 Sponsors: AG1 & LMNT 00:46:00 Free Diving, Spleen, Thyroid Hormone, Performance Enhancement 00:52:00 Dive Reflex, Immune System; Swimming & Health; Coastal Regions & Genetics 00:55:17 Female Free Divers, Haenyeo, Cold Water, Age, Protein 01:03:20 Human Evolution & Diet, Lactase, Fat 01:05:07 Korean Female Free Divers & Adaptations, Cardiovascular, Pregnancy 01:10:13 Miscarriages & Genetic Selection; Bajau, External Appearance, Mate Selection 01:17:15 Sponsor: Function 01:19:03 Free Diving, Underwater Vision; Super-Performers & Genetics 01:25:01 Cognitive Performance, Autism, Creativity; Genetic Determinism & Mindset 01:36:30 Genetics & Ethics, CRISPR, Embryo Genetic Screening 01:44:36 Admixture, Genetics; Are Humans a Single Species? 01:49:39 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices
It's not easy for two sisters to star in some of the most ICONIC roles in pop culture history, but these siblings did just that! How I Met Your Mother actress Ashley Williams, and Father of the Bride star Kimberly Williams Paisley join Kate and Oliver in a star-studded edition of Sibling Revelry. Plus, JUST WAIT until you hear how the "Father of the Bride" movie led Kimberly down the aisle in real life!See omnystudio.com/listener for privacy information.
En este episodio reflexiono sobre la evolución de mi canal, desde aquellos inicios enseñando técnica fotográfica en plena pandemia, hasta el enfoque actual más orientado al cacharreo, la fotografía gastronómica y las colaboraciones con marcas.Pero… algo me tira de nuevo a los orígenes.Anuncio oficialmente una nueva serie en YouTube: BÁSICOS DE FOTOGRAFÍA. ¿El objetivo? Volver a crear contenido formativo desde cero, con un enfoque sencillo, claro y directo, tanto para usuarios con cámaras réflex como mirrorless.Además, comparto cómo el canal creció gracias a esa formación, el papel que jugó el Patreon, y cómo quiero volver a renovar y actualizar algunos cursos que siguen totalmente vigentes pero con energía nueva.Ah, y todo esto grabado con la pulsera PLAUD NOTE PIN, el nuevo patrocinador del canal, que me permite transcribir automáticamente mis podcasts para que no se pierda nada. Enlace aquí debajo si quieres una:➡️➡️ ENLACE PLAUD: https://bit.ly/plaud_ai_ruben**COMPRA EN FOTOK desde este enlace y pon el cupón GABELLIFTK en tu carrito de la compra para llevarte un regalo.WEB FOTOK: https://fotok.es/?aff=y206___________________WEBS: https://www.rubengabelli.comhttps://fotografodecomida.esYOUTUBE: https://cutt.ly/ft3QEHF PATREON: https://www.patreon.com/RubenGabelli INSTAGRAM: @rubengabelli
Sigue la promoción de «Superman». Tenemos nuevas imágenes y pósteres oficiales. ¿Está mejorando la cosa? Además tendremos muchas más noticias y nuestra secciones habituales. ❇️ Si quieres saber más de El Sótano de Planet os dejamos todos los enlaces de interés: 🔷 PÓDCAST IVOOX: https://www.ivoox.com/podcast-podcast-el-sotano-del-planet-podcast-superman_sq_f173777_1.html 🔷 TWITCH: https://www.twitch.tv/elsotanodelplanet 🔷 YOUTUBE: https://www.youtube.com/channel/UCVezUEZeVU2pDJvQ0NFM6CQ 🔷 INSTAGRAM: https://www.instagram.com/elsotanodelplanet/ 🔷 FACEBOOK: https://www.facebook.com/ElSotanoDelPlanet 🔷 TWITTER: https://twitter.com/SotanoPlanet 🔷 DISCORD: https://discord.gg/qtarkDZpyB (Si no funciona la invitación, solicitadlo por redes sociales y os ofreceremos la nueva invitación activa) 🔷 E-MAIL: ElSotanoDelPlanet@gmail.com 🔷 PÓDCAST ITUNES: https://podcasts.apple.com/es/podcast/podcast-el-s%C3%B3tano-del-planet-podcast-superman/id1041625748 🔷 PÓDCAST SPOTIFY: https://open.spotify.com/show/1nlF54BDI8dsIxo6Az51zK?si=5XQJoWR1Rq6kN-FMo9RN2g 🔷 PÓDCAST ANTIGUOS: https://go.ivoox.com/sq/1136166
Historian Tom Holland narrowly escaped a career writing vampire novels to become the co-host of the wildly popular podcast The Rest Is History. At Steve's request, he compares President Trump and Julius Caesar and explains why the culture wars are arguments about Christian theology. SOURCES:Tom Holland, historian and host of The Rest is History. RESOURCES:Dominion: How the Christian Revolution Remade the World, by Tom Holland (2019).Rubicon, by Tom Holland (2005). EXTRAS:Unforgiving Places: The Unexpected Origins of American Gun Violence, by Jens Ludwig (2025)."A Solution to America's Gun Problem," by People I (Mostly) Admire (2025)."Richard Dawkins on God, Genes, and Murderous Baby Cuckoos," by People I (Mostly) Admire (2024).
Host: Denise M. Dupras, M.D., Ph.D. Guest: Saad J. Kenderian, M.B., Ch.B. Dr. Saad Kenderian discusses the use of CAR-T cell therapy, a groundbreaking treatment that genetically modifies a patient's T-cells to target and destroy cancer cells, particularly in blood cancers like leukemia and lymphoma. He highlights the importance of identifying eligible patients, monitoring treatment response, and applying genomics to guide the future of personalized cancer immunotherapy. Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts
Tomatoes come in all kinds of colors, sizes, and flavors. But what's going on at the genetic level? What makes a tomato red or yellow? Tiny or giant?Researchers are mapping the genomes of 22 varieties of nightshades—the family of plants that includes tomatoes, potatoes, and eggplants. They located the genes that control the size of tomatoes and eggplants and then used CRISPR gene editing to grow bigger fruits without sacrificing flavor.Geneticist Michael Schatz joins Host Ira Flatow to talk about his latest research into nightshade genomes and the current state of genetically modified crops.Guest: Dr. Michael Schatz, professor of computational biology and oncology at Johns Hopkins University, based in Baltimore, Maryland.Transcript will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
Dearie is a sci-fi novelist. He also holds novel criticisms of Christianity, and perhaps a solution. more at dogmadebate.com
Welcome to Quick Hits: Blasts from The Past. Join Karen as she explores her podcast archives, offering you short, impactful excerpts from standout episodes. In just 15 minutes, you'll experience the essence of past conversations, packed with valuable insights and memorable moments from our guests. If you want to dive deeper, you'll find links to the full episodes in the show notes below. Listen to the full episode. What if your weight loss struggles aren't about discipline or calories—but about how your genes process inflammation, carbs, and toxins? In this episode, I'm joined by functional health expert and former malpractice attorney Sam, who breaks down how your genetic pathways affect everything from weight loss resistance to detox capacity, hormone metabolism, and food sensitivities. Forget obsessing over one red MTHFR gene—this episode will teach you how to see the whole genetic picture, so you can personalize your diet, detox, and supplement strategy for real results. What We Cover: Why some women gain more fat the more they exercise (yep, it's genetic!) The Muffin Test: A surprising clue that your inflammation genes are out of balance Inflammation, water retention, and the hidden reason for overnight weight gain The concept of hormonal toxic fat and how poor detoxification can trap weight The myth of “willpower” and why toxic load may be sabotaging your best efforts How mineral deficiencies + heavy metals mess with your enzyme function What your copy number genes say about your carb tolerance and ideal diet Why your fat cells are like toxic closets—and how to open them safely Why It Matters: Your genes are not a death sentence—they're a user manual. Whether you struggle with weight loss, detox overload, mood swings, or midlife mystery symptoms, understanding your genetic code is the first step to healing. This episode will empower you to stop blaming your body—and start working with it instead. Visit Dr. Sam Shay's website here. Sponsors Get $100 off your CAROL bike with coupon code HORMONE here. Are you in peri or post menopause and looking to optimize your hormones and health? At Hormone Solutions, we offer telemedicine services and can prescribe in every U.S. state, as well as in British Columbia, Alberta, and Ontario in Canada. Visit karenmartel.com to explore our comprehensive programs: Bioidentical Hormone Replacement Therapy Individualized Weight Loss Programs Peptide Therapy for weight loss Interested in our NEW Peptide Weight Loss Program? Join today and get all the details here. Join our Women's Peri and Post Menopause Group Coaching Program, OnTrack, TODAY! To our nursing audience members, our podcasts qualify for nursing CE @ RNegade.pro. Provide # CEP17654. Your host: Karen Martel Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert Karen's Facebook Karen's Instagram
Lisa Markowitz currently teaches Introduction to Cultural Anthropology, People and their Food, Anthropology of Latin America, Globalizing Inequalities, Food Justice, and Contemporary Issues in Anthropology, at the University of Louisville. Markowitz's research has focused on inequities in regional and global agrifood systems and popular efforts to transform them. These linked themes have informed her writing and scholarly-civic engagement in Andean South America and the upper U.S. South. She has carried out ethnographic field research in Peru and Bolivia, exploring the situation of peasant farmers and ranchers and their use of communal or collective strategies to improve their production systems and economic bargaining power. This experience led to a long-term interest in Andean food and agriculture as well as an engagement with building equitable food systems in the United States Her work has also addressed the roles of Non-governmental organizations as change agents in South America and the United States. Her most recent project concerns the grocery industry. Michael Perlin: Dr. Michael Perlin teaches Biology 330 Genetics & Molecular Biology, Biol 410 Misuse of Biology in Film and Pop Culture, Biol 542/642 Gene Structure and Function, Biol 416 Biotechnology Methods, and Biol 575/675 Evolution of Genes and Genomes. As a biologist Dr. Michael Perlin investigates the evolution of host/pathogen interactions, primarily at the molecular genetics and biochemical levels. The research in Michael Perlin's lab focuses on the evolution of interactions between pathogens and the hosts on which they cause disease. At present, this work has two main areas of emphasis: fungal/plant interactions and population dynamics of bacteria resistant to antibiotics.
Escuche esta y más noticias de LA PATRIA Radio de lunes a viernes por los 1540 AM de Radio Cóndor en Manizales y en www.lapatria.com, encuentre videos de las transmisiones en nuestro Facebook Live: www.facebook.com/lapatria.manizales/videos
Matters Microbial #91: You Are What Your Genes Feed Your Microbiome May 16, 2025 Today, Dr. Emily Davenport, Assistant Professor in the Department of Biology and Huck Institutes of the Life Sciences at Penn State University, joins the #QualityQuorum to tell us about the research her team does, studying how our own genes impact our microbiomes. Host: Mark O. Martin Guest: Emily Davenport Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A description of GWAS (“Genome Wide Association Study”). Here is an introductory video about the concept. An explainer on organoids. An essay about the diversity of the host microbiome (i.e. is there a “healthy” microbiome?). An article of the work of Dr. Sarkis Mazamian on how individual host genes and bacterial genes can impact the microbiome. A nice write up for Dr. Mazamian's work showing how host genes and bacterial genes can work together…or not. An oldish video of how the infant microbiome develops over time by Dr. Rob Knight's research group. An article on the same topic from Dr. Ruth Ley. An essay on the mucosal microbiota, rather than the fecal microbiome. An interesting member of the human microbiome, Akkermansia that might be related to obesity. Another interesting member of the human microbiome, Bifidobacterium, which appears to be associated with host lactose metabolism. Yes, there is a Giant Microbes plush toy. An overview of the impact of host genetics on the microbiome by Dr. Davenport. A definition of heritability. An overview of the Hutterites and how their study has advanced genetics. An explainer of the power of twin studies in genetics. A fascinating article about ancient dental plaque microbiome by Dr. Davenport and others. Dr. Davenport's faculty website. Dr. Davenport's research group website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
Dayna Parker: Dayna, who is an expert in multiple intuitive modalities including Gene Keys, is our guest today sharing how she came into her intuition, learned how to trust it, and utilize it in every aspect of her life and business. We also dive into the ethics of spiritual work, and the need of the practitioner to put their client's intuition even before their own. How the future of "light work" is really helping everyone find and hone their own God-given gifts. We dare you to not feel more inspired after watching/listening! Want to watch the podcast instead? We're on...YouTubeWant to connect with Dayna?: https://linktr.ee/daynamiteWant to check out Camille's free course?: https://connectwithcamille.com/discover-your-angelsWant to drop Elle or Camille a line, book a session, or get into their group classes?: https://throughtheveilpodcast.comWant to join our private Facebook group to meet like-minded people interested in discussing spiritual gifts?: https://www.facebook.com/groups/255541367482301Want to read Camille's book?: https://www.amazon.com/Let-Angels-Carry-You-Connecting/dp/B0CQK4PYCSMusic by: Music by: Born Twice // Mark Tracy#intuitive #genekeys #spiritualgifts #intuition
Do free divers of Jeju Island have a 'superpower' in their genes? Guest: Dr. Melissa Ilardo, Evolutionary Geneticist at the University of Utah Learn more about your ad choices. Visit megaphone.fm/adchoices
“Después oí la voz del Señor, que dijo: ‘¿A quién enviaré? ¿Quién irá de nuestra parte?' Entonces respondí: ‘Aquí estoy, envíame a mí' ” (Isa. 6:8).Lucho Schneider y Sebastián Martínez. Musicalización: Claudio Graff
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“A Trump le gusta provocar incendios y luego aparecer con uniforme de bombero”. Dos días en la vida nunca vienen nada mal: el sueño cumplido de Marita, la argentina que pudo conocer a su familia checa.
How do we create continuing education that prepares clinicians to deliver life-changing diagnoses with both precision and compassion?In this episode, we explore what happens when the scientist's role as a communicator intersects with the lived experience of parenting a child with a rare disease. I'm talking with Dr. Jennifer Brown, a geneticist who recently published a memoir, When the Baby is not OK: Hopes and Genes, based on her experience of parenting children diagnosed with PKU through newborn screening. For CME professionals, this episode is a call to rethink how we center narrative, ethics, and emotional intelligence in our content, especially when evidence alone isn't enough to support meaningful patient care. Learn how outdated narratives and clinical language can alienate patients—and how reframing them can build trust and support retention in care. Hear why integrating lived experience into CME is essential for designing education that resonates beyond the exam room. Discover how personal storytelling, ethical reflection, and patient advocacy can enrich data-driven CME writing. ▶️ Press play to discover how Dr. Jennifer Brown's dual lens—as a geneticist and parent—can sharpen your skills as a more empathetic, informed CME professional. Connect with Jennifer LinkedIn Goodreads Author Site Bluesky YouTube
Grace Bervoets talks about living with cystic fibrosis and cystic fibrosis related-diabetes. Amanada Stride, who works as a diabetes consultant helping people with cystic fibrosis related-diabetes, explains the many challenges of this unusual type of diabetes.Send us a text
In this episode of Behind the Genes, we explore the hopes, concerns and complex questions raised by the idea of a lifetime genome — a single genomic record used across a person's life to guide healthcare decisions. Drawing on conversations from Genomics England's Public Standing Group on the lifetime genome, our guests explore what it might mean for individuals, families and society to have their genome stored from birth, and how it could transform healthcare. The discussion reflects on the potential for earlier diagnoses, better treatments and long-term prevention, alongside pressing ethical concerns such as data security, consent, and the impact on family dynamics. Participants share their views and discuss the future role of genomic data in medicine, with insights into how trust, equity and public dialogue must shape this evolving field. Our host for this episode, Dr Harriet Etheredge, is joined by Suzalee Blair-Gordon and Gordon Bedford, two members of the Genomics England's Public Standing Group on the lifetime genome, and Suzannah Kinsella, Senior Associate at Hopkins Van Mil, a social sciences research agency that helped to facilitate this work. Together, they consider the broader societal implications of lifetime genomic data, and how public involvement can help guide policy and practice in the UK and beyond. This conversation is part of our ongoing work through the Generation Study, exploring how genomics can be used responsibly and meaningfully from birth onwards. You can listen to some of our Generation Study episodes by following the links below. What can we learn from the Generation Study? How has design research shaped the Generation Study? What do parents want to know about the Generation Study? "This isn't just a science project, it's about designing a future where everyone feels included and protected. We need more voices, parents, young people, underrepresented communities, to keep shaping it in the right direction." You can download the transcript, or read it below. Harriet: Welcome to Behind the Genes. Suzalee: I have come to terms with the thought that life is unpredictable and I have already begun to accept any health condition that comes my way. Believe you me, I have been through the stage of denial, and yes, I have frozen upon hearing health diagnoses in the past but now I believe that I am a bit wiser to accept the things that I cannot change and to prepare to face the symptoms of whatever illness I am to be dealt with or to be dealt to me. If the analysis of my genome can help me to prepare, then yes, I am going to welcome this programme with open arms. Harriet: My name is Harriet Etheredge, and I am the Ethics Lead on the Newborn Genomes Programme here at Genomic England. On today's episode I'm joined by 3 really special guests, Suzalee Blair and Gordon Bedford, who are members of Genomics England's Public Standing Group on Lifetime Genomes, and Suzannah Kinsella, Senior Associate at Hopkins Van Mil, a social sciences research agency that has helped us to facilitate this work. Today we'll be discussing the concept of the lifetime genome. What do we mean when we say, ‘lifetime genome'? How can we realise the promise of the lifetime genome to benefit people's healthcare whilst at the same time really appreciating and understanding the very real risks associated? How do we collectively navigate ethical issues emerging at this genomic frontier? If you enjoy today's episode, we would really love your support. Please share, like and give us a 5-star rating wherever you listen to your podcasts. And if there's a guest that you'd love to hear on a future episode of Behind the Genes, please contact us on podcast@genomicsengland.co.uk. Let's get on with the show. I'll start off by asking our guests to please introduce yourselves. Suzalee, over to you. Suzalee: Thanks, Harriet. So I am a proud mum of two kids, teacher of computing at one of the best academic trusts in the UK, and I am also a sickler, and for those who don't know what that means, I am living with sickle cell disease. Harriet: Thank you so much, Suzalee. Gordon, over to you. Gordon: I'm Gordon Bedford, I'm a pharmacist based in The Midlands. I've worked in hospital and community pharmacy. I have a genetic condition, which I won't disclose on the podcast but that was my sort of position coming into this as I'm not a parent of children, but it was coming in from my perspective as a pharmacist professional and as a member of society as well. Harriet: Thank you so much, Gordon. And, last but certainly not least, Suzannah. Suzannah: So, yes, Suzannah Kinsella. I am a social researcher at Hopkins Van Mil, and I had the pleasure of facilitating all of the workshops where we gathered together the Public Standing Group and working on reporting the outcome from our discussions, so delighted to be coming in from South London. Harriet: Thank you so much, everyone, and it's such a pleasure to have you here today. So, many regular listeners to Behind the Genes will now that Genomics England is currently undertaking the Generation Study. I'm not going to speak about it in much detail because the Generation Study has already been the subject of several Behind the Genes podcasts and we'll put some links to these in the show notes for this episode. But briefly, the Generation Study aims to analyse whole genomes of 100,000 newborn babies across England, looking for 250 rare conditions. We have a view to getting these children onto treatments earlier and potentially enhancing their lives. The Generation Study is a research project because we don't know if the application of this technology will work. And as a research project we can also answer other important questions, such as questions about a lifetime genome. When we invite parents to consent to the Generation Study on behalf of their newborn babies, we ask to store babies' genomic data and linked healthcare data in our trusted research environment. This helps us to further research into genes and health. But a critical question is ‘what do we do with these data long term?' And one of the potential long-term uses of the data is to revisit it and re-analyse it over a person's lifetime. We could do this at critical transition points in life, like adolescence, early adulthood or older age, with the aim of using the genomic data to really enhance people's health. But this is a very new concept. There's been little work on it internationally, however I am pleased to say that interest seems to be picking up. In the Generation Study, whilst we are at the present time doing no lifetime genomes work, we are looking to explore the benefits, risks and potential uses of the lifetime genome. This Public Standing Group on lifetime genomes was our first foray into this area. So, I'd like to start off by inviting Suzannah to please explain a bit more about what the Public Standing Group is, why it was created and how a group like this helps us to generate early deliberation and insight. Suzannah: So, the first thing I should talk about is who were these 26 people that formed part of this group, and the first thing to say is that they were a wide range of ages and backgrounds from across England, so some from Newcastle, some from London and everywhere in between. And these 26 people all had one thing in common, which is they had all taken part in a previous Genomics England public dialogue, either the whole genome sequencing for newborn screening which took place in 2021, or in a more recent one in about 2022/23 which was looking at what should Genomics England think about in terms of research access to data that's drawn from the Generation Study. So, the great thing was that everybody had already some previous knowledge around genomics, but the concept of a lifetime genome was completely new. So these 26 people met on 5 occasions over the period of 2024, mostly meeting face to face, and really the task that they were given was to look at the lifetime genome and look at it from every angle; consent, use, information sharing and all sorts of other aspects as well. Harriet: Gordon and Suzalee, you were participants in our Public Standing Group, I'd love to hear from you what your roles in the Standing Group were and what you found most interesting, but also for you which bits were the most challenging. Suzalee, shall we start with you? Suzalee: For me the most interesting bits were being able to learn about one's genome and, through Genomics England and their possible use of pharmacogenetics, could determine the specific medication that could be prescribed for a new health condition instead of expensive and possibly tonnes of adverse side effects trial and error medications. Additionally, as a person living with sickle cell disease, I got the chance to share my story and to give voice to people living with the same condition or similar to myself, and how the potential of the genomics newborn programme could help our future generation. There were some tricky bits, and the most challenging bit was to initially discuss and think about the idea of whether or not a parent might choose to know or not to know the potential of their newborn developing or prone to develop a certain condition based on the data received from the programme. My thought went back to when I gave birth to my first child 16 years ago and I was adamant to know if my child would inherit the sickle cell disease, what type, if it would be the trait. In my mind I knew the result, as my haemoglobin is SC and their dad is normal, but I wanted to be sure of my child's specific trait. But then I asked myself, “What if my child was part of the Newborn Genomes Programme, then the possibility exists that other health conditions could be detected through the deep analysis of my child's genome. Would I really want to know then? What would be the psychological effect or, in some cases, the social impact of what I have to learn?” Harriet: Thank you so much, Suzalee. And I think it's just wonderful to hear about the personal impacts that this kind of work can have and thank you for bringing that to us. Gordon, I'll hand over to you. I'd be really interested in your thoughts on this. Gordon: So my role in the Public Standing Group was to give my section of society my experiences in life to bring them together with other people, so experiences like Suzalee and the 24 other people that joined us on the study, to bring our opinions together, to bring our wide knowledge and group experiences of life. And it's important to have a wide group, because it forces us to wrestle with differences of opinion. Not everybody thinks like I do. As a pharmacist, I can see the practical side of genomics, like pharmacogenomics, where we could use a baby's genome to predict how they'll respond to drugs over their lifetime. That's a game-changer for avoiding adverse reactions or ineffective treatments, but not everybody's sold on it. Some in our group worried about privacy, who gets this data, or ethics, like whether it's fair to sequence a baby who can't say yes or no. I get that. I don't have children, but I hear those things clearly. The most interesting bits for me, the pharmacogenomics discussion in meeting two stood out, everyone could see the tangible benefits of tailoring medicines to a person's genome, making treatments more effective, and in Meeting 5 designing our own lifetime genome resource was also fascinating. Ideas like it for public health research showed how far-reaching this could be. Some of the challenging sides of things that I came across, the toughest part was grappling with unknowns in Meeting 4, like how to share genetic info with your family without damaging relationships. Those risks felt real, and it was hard to balance them against the benefits, especially when trust from groups like minority ethnic communities is at stake. Harriet: Thank you so much, Gordon. I think from you and Suzalee it's so fascinating to hear how you were grappling, I think, with some of your personal and professional feelings about this and your deeply-held personal views and bringing those first of all out into the open, which is something that is very brave and we really respect and admire you doing that, and also then understanding that people do hold very different views about these issues. And that's why bring these issues to an engagement forum because it's important for us to hear those views and to really understand how people are considering these really tricky ethical issues. So, Suzalee, I'm wondering from your perspective how do you feel we can really be respectful towards other people's points of view? Suzalee: Yes, Harriet. In spite of the fact that we had different viewpoints on some topics discussed, every member, researcher, presenter and guests were respectful of each other's point of view. We all listened to each other with keen eyes, or sometime squinted eyes, with a hand on the chin which showed that what was being said was being processed or interpreted. All our views were recorded by our researchers for further discussion and analysis, therefore I felt heard, and I believe we all felt heard. Harriet: Do you have any examples that you can recall from the groups where there were differing points of view and how we navigated those? Gordon: Where we had screening at age 5, but we agreed on an opt-out model, because it could help spot issues early. But some worried - psychological impacts, knowing too much too soon. But we looked at an opt-out model rather than an opt-in model because it's easier to say to somebody, “If you don't want to continue with this, opt out” rather than trying to get everybody opting in at every different age range. So, as we reach the age of 5, 10, 15, 20, whatever, it's easier to get people to opt out if they no longer want to be part of that rather than trying to get them to opt in at each stage throughout their life. Harriet: Suzannah, do you have anything to add there as a facilitator? How did you feel about bringing these different points of view together? Suzannah: Yeah, you asked about where are the tensions, where do people maybe agree a bit less or agree and hold different views, and I think what stands out is particularly… There was an idea floated by one of the speakers about you could have your DNA data on an NHS app and then, let's say if you're in an emergency, a paramedic could have access to it or others. And that really I think brought out quite a wide range of perspectives of some in the group feeling, “You know what, anyone who has an interest, anyone that can help my health, let them have access to it as and when, completely fine,” and others took a more cautious approach saying, “This is my DNA, this is who I am, this is unique to me, my goodness, if someone, some rogue agent manages to crash the system and get hold if it goodness knows what nightmare scenario it could result in,” and so had a much more keep it locked down, keep it very limited approach to having access to your lifetime genome data and so on. So that was a really interesting example of people going, “Yep, make it free” and others going, “No, just for very specific NHS roles,” which I thought was fascinating. Harriet: Yeah, thank you so much, Suzannah. And I think it's a real tangible challenge that those of us working in this area are trying to grapple with, is finding the middle ground here with all of the challenges that this involves, for instance, our data infrastructure and the locations at which data are held. Advert: The Genomics England Research Summit is fast approaching and registration is now open! Join us for this one day in-person event on Tuesday 17 June 2025. This year's agenda dives into rare condition diagnosis, cancer genomics, pharmacogenomics, therapeutic trials, and the impact of emerging technologies. Hear from leading experts and inspirational speakers as we explore the present and future of genomics and the latest research and technology from the Genomics England research community. Keep an eye on the website, genomicsresearchsummit.co.uk for all the details and to secure your spot. Spaces are limited, so don't miss out. We'll see you at the summit! Harriet: I think this brings us really nicely onto looking at some of the ethical, legal and social issues that we need to think through when we're considering the lifetime genome. I'm wondering if we can expand on some of these and the importance of addressing them. Gordon, would you like to give us your thoughts? Gordon: Sure, thank you. Our job was to dig into how a baby's genome could be used over the lifetime, think pharmacogenetics for better drugs, early childhood screening for conditions or carrier testing to inform family planning. We saw huge potential for individual health like catching diseases early, but also broader impacts like reducing NHS costs through prevention. Weighing the risks and benefits. The benefits like earlier diagnosis or research breakthroughs grew clearer over time with ratings rising from 4.1 to 4.7 - that's out of, I believe, a figure of 5, but risks like data breaches and family tensions over shared genetics stayed significant. We agreed the benefits could outweigh the risks but only with mitigations like transparent governance and strong security. And what are the global implications moving forward? What we discussed isn't just for the UK, it's feeding into the global conversation about newborns in genomic research. That responsibility made us think hard about equity, access, and how to build public trust. Harriet: Thank you, Gordon, I think there's so much there to unpack. And one point I think in particular that you've mentioned, and this came out really strongly as one of our main findings from these groups, was the way that a lifetime genome and the way that we might deliver that information could really impact family dynamics in ways that we might not have really thought of before or in ways that we really have to unpack further. And, Suzalee, I'd love to hear from you about this, how might diverse family dynamics need to be considered? Suzalee: Harriet, as it relates to diverse family dynamics a burning legal issue, which is then triangulated into being considered an ethical issue as well as a social issue, was the question can siblings of sperm donors be informed of life-threatening genomic discoveries? Whose responsibility is it? Will policies now have to be changed or implemented by donor banks to take into consideration the possibility of families being part of the new genomes programme? Harriet: Yeah, thank you, Suzalee. I think there's so much there that we have to unpack and in the Generation Study we're starting to look at some of those questions, but going forward into potential risks, benefits and uses of the lifetime genome, all of these new technologies around human reproduction are things that we're going to have to consider really, really carefully through an ethical and legal lens. Suzannah, I wondered if you have anything to add to these as major ethical issues that came out in these groups. Suzannah: I think, as you say, people were so fascinated by the idea of this information landing in a family, and where do you stop? Do you stop at your siblings, your direct family, the brothers and sisters of a child? Do you go to the cousins? Do you go to the second cousins? It's this idea of where does family stop. And then people were really interested in thinking about who does the telling, whose job is it? And we had this fascinating conversation – I think it was in Workshop 3 – where this very stark fact was shared, which is the NHS doesn't know who your mother or your father or your siblings are; your NHS records are not linked in that way. And so that presented people with this challenge or concern that “Actually, if I get quite a serious genetic condition diagnosed in my family whose job is it to share that information, what support is there to do that and how far do we go?” So, I think people were really fascinated and hopeful that Genomics England will really be at the vanguard of saying, “How do we as we move into an era of more genetic data being used in our healthcare, how's that managed and how's it shared?” Harriet: Yeah, thank you so much, Suzannah. So I think that what's coming out through everything that you're all saying is the huge breadth of issues that came up here. And of course we're seeing, very encouragingly, so many nods to the potential benefits, especially around things like pharmacogenomics, but we are seeing some risks. Gordon, I wondered if you'd like to elaborate a bit further. Gordon: So, something that came up, and it divided the group quite considerably, carrier status divided us. Some saw it as reducing disease prevalence and others feared it could fuel anxiety or stigma amongst the family or other families. It showed how personal these choices are and why families need control over what they learn. Harriet: Yeah, it's a very good point, and carrier status is something that could be a conceivable use of our lifetime genome record. Suzannah? Suzannah: Just building off what Gordon was talking about, I remember there were also discussions around are we getting into a state where this is about eradication of so many different conditions, and actually how does that sit with a society that is more embracing, accommodating and supportive of people with different health needs. So, I think that was quite a big ethical discussion that was had, is, and particularly where we think about what we screen for in the future over time and so forth, people really being conscious that “Actually, where are we going with this? Are we risking demonising certain conditions and saying we don't want them on the planet anymore and what are the consequences of that?” Advert: If you're enjoying what you've heard today and you'd like to hear some more great tales from the genomics coalface, why don't you join us on the Road to Genome podcast, where our host, Helen Bethell, chats to the professionals, experts and patients involved in genomics today. In our new series, Helen talks to a fantastic array of guests including the rapping consultant, clinical geneticist Professor Julian Barwell about Fragile X Syndrome, cancer genomics and the holistic approach to his practice. A genuine mic-drop of an interview. The Road to Genome is available wherever you get your podcasts. Harriet: And I think came to a point in our final meeting where we were asking our participants, so Suzalee and Gordon and everybody else in the room, whether you might consider having a lifetime genome for yourself and what that would look like. We'd love to share your views about that, and Suzalee, I'm wondering if you can share your thoughts on that with us first. Suzalee: Definitely. I would wholeheartedly be interested in the lifetime genome programme if it was offered to me right now. I believe that the pros for me are phenomenal. I have come to terms with the thought that life is unpredictable and I have already begun to accept any health condition that comes my way. Believe you me, I have been through the stage of denial, and yes, I have frozen upon hearing health diagnoses in the past but now I believe that I am a bit wiser to accept the things that I cannot change and to prepare to face the symptoms of whatever illness I am to be dealt with or to be dealt to me. If the analysis of my genome can help me to prepare, then yes, I am going to welcome this programme with open arms. Harriet: Thank you, Suzalee. And, Gordon, how did you feel about it? Gordon: Being part of the group showed me how genomics is both thrilling and daunting. I'd lean towards ‘yes' for a lifetime genome resource for the chance to detect conditions early, but I get why some people may say ‘no' over the data fears or ethical lines. This isn't just a science project, it's about designing a future where everyone feels included and protected. We need more voices, parents, young people, underrepresented communities, to keep shaping it in the right direction. Laws would have to be enacted regarding the storage, use and availability of genetic data. We haven't yet seen as well, how AI's complete benefits in medicine will develop over time. Harriet: Thank you so much, Gordon and Suzalee, for sharing that. And, Suzannah, I know that at the end of the Public Standing Group we generally asked all of our participants whether they would choose to have a lifetime genome, the same sort of question I've just asked Suzalee and Gordon. I wondered if you could just briefly give us an overall sense of how the Public Standing Group participants felt about that. Suzannah: Yes, so it's interesting to see that actually not everyone said, despite spending a year or almost a year discussing this, not everyone said, “Sign me up,” 6 said, “No” or “Maybe.” And the reasons they gave, this idea, “Well, all this data, could a government sell it off? What guarantees have we got?” So that was a reason. Somewhat of a concern also about breaches but also this idea of “What do I really want to know? Do I want to have a lifetime resource that can tell me what's going to happen next in my health?” and some say, “Let me deal with it when the symptoms start coming and that's the way I want to handle it.” So, yeah, about 20 said, “I'd be really interested,” similar to Suzalee and Gordon, 6 on the fence or firmly, “No thanks.” Harriet: Thank you so much, Suzannah. I think your point about uncertainty there is so relevant and important to us. We see uncertainty across genomics and we're layering that here with uncertainty about futures, we're layering that with uncertainty about health. And I hope that this has served to really illustrate the magnitude of the challenge we're looking at here and I think also why for us as Genomics England this is just something we're exploring. There's so much to unpack, there's so much still to be done. In terms of our next steps for Genomics England, it feels like we could speak about this for a week but I'm going to have to wrap it up here. So, for us what are our next steps? We hope really that as we publicise the findings of this Public Standing Group and when we start combining some of our work and looking at it in harmonisation with the work that others are doing across the world, we might be better positioned to understand the potential future directions that a lifetime genome could take. That's obviously very, very exciting because we expect to see this area of enquiry expanding significantly over the coming years. And we're already hearing about a number of other countries who are also doing birth cohort studies like we are who might hope to use similar applications of the lifetime genome going forward. So, there's a real opportunity for us here to collaborate and it's really heart-warming that the voices of our participants in this Public Standing Group can be used to facilitate that level of engagement. For us at the Generation Study, we're already looking at the next iteration of our lifetime genomes work and we're being led by the findings of this Public Standing Group as we move forward, specifically in that we're going to be starting to take some of these emerging themes to the parents of our Generation Study babies to really find out how they would feel about them. Harriet: I'd like to extend my sincere gratitude to all for being my guests today, Suzannah Kinsella, Suzalee Blair and Gordon Bedford. Thank you so much for your time and joining me in this discussion of the lifetime genome. If you'd like to hear more content like this, which I am sure you would, please subscribe to Behind the Genes on your favourite podcast app. Thank you so much for listening. I've been your host, Dr Harriet Etheredge. This podcast was edited by Bill Griffin at Ventoux Digital and produced by Deanna Barac for Genomics England.
My guest is Dr. Christopher Gardner, Ph.D., professor of medicine and director of nutrition studies at Stanford. He is known for his pioneering research on the impact of dietary interventions on weight loss and health. We compare ketogenic, vegetarian, vegan and omnivorous diets—and why there is no one-size-fits-all approach. All agree, however, that eliminating or dramatically reducing processed foods is best for health. We discuss the protein needs controversy; plant vs. animal proteins; the importance of fiber and low-sugar fermented foods for gut health and inflammation; and how diet affects gene expression. We also review food allergies—including gluten, wheat, dairy and soy—as well as raw dairy. The episode offers data-supported advice for healthier eating. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman Mateina: https://drinkmateina.com/huberman BetterHelp: https://betterhelp.com/huberman LMNT: https://drinklmnt.com/huberman Levels: https://levelshealth.com/huberman Timestamps 00:00:00 Christopher Gardner 00:02:32 Is there a Best Diet?, Individual Needs, Geography & Diet, Lactose 00:11:02 Sponsors: Eight Sleep & Mateina 00:13:49 Raw Milk, Lactose Intolerance 00:20:33 Wheat Allergies, Gluten Intolerance; Celiac Disease 00:25:12 Processed Foods, Food Dyes, Research Outcomes, NOVA Classification, GRAS 00:33:44 Processed Foods, Economic & Time Considerations, US vs European Products 00:39:59 Food Industry Funding, Investigator Influence, Equipoise, Transparency 00:50:10 Sponsors: AG1 & BetterHelp 00:53:11 Industry Funding, National Institute of Health (NIH) 00:56:41 Whole Food, Plant-Based Diet; Diet Comparison, DIETFITS, A TO Z Study 01:10:24 Nutrition Naming, Omnivore, Meat, Animal Feeding Operations (CAFO) 01:17:14 Transforming American Diet; Taste, Health & Environment 01:22:26 Sponsor: LMNT 01:23:43 Food Preparation, Chefs, Improve School Food 01:29:54 Scalability, Mega-Farms, Small Farm & Farmer Loss 01:34:25 Protein Requirements, Dietary Protein Recommendations, Standard Deviations 01:45:33 Protein & Storage 01:52:12 Plants & Complete Proteins?, Legumes, Bioavailability 02:01:58 Sponsor: Levels 02:03:17 Beyond Meat, Impossible Meat, Ingredients, Sourcing Meat, Salt 02:09:18 Vegan vs Omnivore Diet, Twin Study, Cardiometabolic Markers, Genes, Microbiome 02:20:24 Health Science Communication, DEXA; “Protein Flip” Diet; Food Patterns, Caloric Intake 02:31:29 Microbiome, Inflammation, Fiber, Tool: Low-Sugar, Fermented Food 02:45:32 Acknowledgements 02:47:55 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures
On today's show we talked about the family genes that you got stuck with. We also talked about what our week looks like and another edition of People Are Dicks!
It's Mother's Day and we are looking at the importance of motherhood from the Word of God. Join us as we see Timothy's heritage of faith that first dwelt in his grandmother and mother in 2 Timothy 1. For more information on The Gathering, check out our website thegathering.online
“Y cantaban un nuevo cántico, diciendo: ‘Digno eres de tomar el libro y de abrir sus sellos; porque tú fuiste inmolado, y con tu sangre nos has redimido para Dios, de todo linaje y lengua y pueblo y nación' ” (Apoc. 5:9, RVR 1960).Lucho Schneider y Sebastián Martínez. Musicalización: Claudio Graff
Durante varios siglos han perdurado leyendas de criaturas nocturnas que se alimentan de sangre humana. El mito del vampiro mezcla lo humano y lo monstruoso, lo terrorífico y lo seductor, lo macabro y lo religioso.En este episodio haremos un recuento de los vampiros más famosos, pero además indagaremos en sus orígenes, escudriñaremos el misterio que los envuelve para encontrar sus debilidades... solo en caso que debamos enfrentar uno.
Christina Shadle is a functional nutritional therapy practitioner (say that five times fast) aaaand she likes herself some wine (who doesn't?). But she also found that over time (literal time, we are talking aging, people), her tolerance and ability to bounce back from a few glasses of her favorite cocktail wasn't what it used to be. So she created her course, WELLNESS FOR WINOS, where the goal is to keep the cocktails and lose the consequences. She joins us to talk the good of habit stacking, detox and balance, and how a 14 day nourishing reset can be a life changer. It's 5 o'clock somewhere, am I right? Might as well enjoy it and feel good after doing so. This one is for the wine lovers out there (like me). _______________________________ Steve is busy at work on the third book in his cozy mystery series, THE DOG WALKING DETECTIVES. Grab the first two and get caught up: Book 1: DROWN TOWN Amazon: https://amzn.to/478W8mp Barnes & Noble: https://bit.ly/3Mv7cCk & Book 2: MURDER UNMASKED Amazon: https://shorturl.at/fDR47 Barnes & Noble: https://shorturl.at/3ccTy
Ever wondered what a genetic counselor actually does—or if you should talk to one? In this episode, Certified Genetic Counselor Laura Barton breaks it all down in simple terms. From inherited cancer risks to what your DNA can (and can't) tell you, this conversation makes genetic counseling easy to understand and incredibly empowering.Rate, Review & Follow to support Beyond Resilience. This helps us support more people and grow our community of resilient and like-minded people who want to move toward a more purposeful and healthy life.For more on Dr. Jamie Renbarger and her coaching practice, visit: https://jamierenbarger.com/For more on Catherine Haffey and her health and wellness platform, visit: https://catherinehaffey.com/For questions & comments, or to submit an episode topic request: beyondresiliencepodcast@gmail.comFollow Beyond Resilience on Instagram: https://www.instagram.com/beyondresiliencepodcast/Follow Beyond Resilience on TikTok:https://www.tiktok.com/@beyondresiliencepodcastFollow Beyond Resilience on YouTube:https: //www.youtube.com/@beyondresiliencepodcast
Welcome to Episode 254 of Autism Parenting Secrets. This week, we're spotlighting the hidden drivers behind chronic inflammation in kids on the spectrum, especially neuroinflammation.Our guest is Bob Miller, a functional genomics pioneer and founder of the NutriGenetic Research Institute. Bob unpacks the ways genetic weaknesses and environmental exposures collide to spark brain inflammation, behavioral challenges, and more.From mold and glyphosate to microplastics and EMFs, you'll discover the specific genes and pathways impacted, and how precision insights can guide what actually helps your child. This episode is deep, but empowering.The secret this week is…DECODE The Inflammation Puzzle You'll Discover:The Toxins That Flip The Inflammation Switch (4:13)Why Some “Healthy” Foods Make Things Worse (9:54)A Clear Breakdown of How Gene Mutations Affect Your Child (21:55)Why EMFs Deserve Your Attention (27:43)Nutrients That Actually Cool Inflammation (29:08)How Functional Genomic Analysis Reveals What To Do (35:02)About Our Guest:Bob Miller is a functional genomics researcher and the founder of the NutriGenetic Research Institute. For over a decade, he's led cutting-edge research on the link between genetic variants and chronic illness, including autism and Lyme disease.Through his educational platforms, including Functional Genomic Analysis software and a certification course for practitioners, Bob equips professionals worldwide with tools to decode the body's genetic blueprint.He's helped thousands understand how environmental toxins trigger genetic vulnerabilities—and how targeted nutritional support can turn the tide.Learn more: www.tolhealth.com and www.functionalgenomicanalysis.comReferences in The Episode:NutriGenetic Research InstituteFunctional Genomic AnalysisAutism Parenting Secrets Episode 109, Genes are CLUES, Not Destiny with Bob MillerAutism Parenting Secrets Episode 118, GENETICS Loads The Gun, ENVIRONMENT Pulls the Trigger with Bob MillerAdditional Resources:To learn more about personalized 1:1 support, go to www.elevatehowyounavigate.comTake The Quiz: What's YOUR Top Autism Parenting Blindspot?If you enjoyed this episode, share it with your friends.
Episode Highlights With Dr. Anne Marie FineWhat happened with autism and why rates have risen from 1 in 10,000 to 1 in 31Some of the multi-faceted reasons that it might be on the riseWhat the literature actually says… you might be surprisedBeyond the genetic theory… the interaction between genes and environment Genes load the gun, environment pulls the triggerWomen with the highest BPA exposure had the highest risk of having children with autismThe CDC is actually keeping track of Americans' chemical exposureWhat to know about mercury and autism risk and how it was taken out of vaccines by 2001The specific study about the Hep B vaccine and why it's relevant Mercury was replaced with aluminum and why this is important How to become the EPA of your own home and avoid some of the biggest risk factorsResources MentionedDr. AnneMarieFine and emeiglobal on InstagramHer LinkedIn and her FacebookHow to Thrive in a Toxic World course: contains a bonus video presentation on environmental contributors to autism.Jaspr air filter - use code wellnessmama for a discountRadiant Life Water Filter
Welcome to the Triple P Life Podcast! Ever wondered why you're chronically tired, gaining weight despite your best efforts, or experiencing brain fog? It might not be age—it could be your hormones. In this eye-opening episode, hormone expert Donna White reveals the shocking truth: men desperately need estrogen and women absolutely need testosterone to thrive. What You'll Learn: The critical difference between synthetic and bioidentical hormones and why it matters Seven key symptoms that signal hormone imbalance (from sleep issues to memory problems) How proper hormone therapy can reduce heart disease risk by up to 52%, Alzheimer's by 52%, and diabetes by 30% Why hormone optimization isn't just for older adults—imbalances can start at any age The environmental factors causing a 50% decline in male testosterone over just 25 years Donna debunks dangerous myths about hormone therapy and cancer risk while explaining how proper hormone balance can dramatically improve your quality of life. Whether you're in your 30s struggling with fatigue or in your 60s wanting to maintain vitality, this conversation reveals why "normal" hormone levels aren't the same as optimal levels. Ready to take control of your health and feel your best at any age? Learn how bioidentical hormone replacement therapy could be the missing piece in your wellness journey. Don't accept declining energy and health as inevitable—discover what's possible when your hormones are properly balanced! Chapters: 00:00 - Introduction to Donna White and BHRT 02:43 - The Hormone Paradox Revealed 05:41 - Donna's Personal Journey with Hormones 08:23 - Defining Hormone Replacement Therapy Types 11:36 - The Hormone Crisis in America 15:33 - Male Testosterone Decline Crisis 17:35 - Balancing Hormones: Estrogen vs Testosterone 20:07 - Why Medical Professionals Ignore Hormones 23:51 - Testosterone and Heart Health 25:48 - Who Should Consider Hormone Testing 28:32 - The Seven Question Hormone Quiz 32:16 - Normal vs Optimal Hormone Levels 35:45 - Dr. Jay's Personal BHRT Experience 38:31 - Continuing Hormone Therapy Long-Term 39:57 - The Future of Bioidentical Hormones 42:28 - Research on Health Benefits of BHRT 46:34 - Genes vs Environment in Hormone Health 49:13 - Understanding Hormone Receptors 51:45 - Taking Control of Your Aging Process 53:36 - Final Thoughts on Hormone Health
Abrimos la Academia de saberes inútiles con Marta Fernández, que nos retrotrae a los grandes apagones de la historia de la ciudad de Nueva York. También nos acompaña El Chojin para explicar cómo el apagón de 1977 propició el nacimiento del Hip Hop.
In this episode of the Startup Tri-Valley Podcast, hosts Yolanda Fintschenko, executive director of Daybreak Labs and i-GATE Innovation Hub, home of the Startup Tri-Valley (STV) Initiative, and Lisa Adamos, Economic Development Manager for the City of Pleasanton, sit down with Reem Mahrat, a serial entrepreneur and founder of EazeBio. Reem shares her personal journey of battling autoimmune disease and how it inspired her to write the book "Feed Your Good Genes: Avoid Autoimmune Disease." She emphasizes the importance of empowering individuals to take control of their health through better choices and understanding gene expression.Reem discusses the innovative work at EazeBio, including the development of a novel biomarker that provides real-time insights into metabolic health. This biomarker helps patients see immediate results from their diet, exercise, and stress management, offering a personalized metabolic dashboard.Reem also highlights the significance of having a strong "why" in entrepreneurship and the importance of teamwork in achieving success.Tune in to hear Reem's inspiring story, her vision for transforming healthcare, and practical advice for founders balancing multiple roles and responsibilities. Watch on YouTube
My daughter Dalia taught me about courage, sweetness, patience, and love. I am who I am because of her. We were meant to be together. -Jessica Fein Welcome to part two of my interview with Jessica Fein, author of Breath Taking: A Memoir of Family, Dreams and Broken Genes. Jess and her husband, Rob, adopted three children from Guatemala. When their daughter, Dalia, began exhibiting balance issues and speech delays, genetic testing revealed a devastating diagnosis of MERRF Syndrome, a degenerative disease that affects the mitochondria and has no cure. In this interview, Jess shares what life was like for her family, and the story is equal parts love and fear of the future. From age 9 to her death at 17, Dalia was an “eyes on patient,” which meant that either a parent or a specially trained medical professional had to have eyes on her 24/7. Dalia couldn't swallow and required a tracheotomy, which meant she was also on a ventilator. She could not speak and was fed through a tube. Dalia couldn't walk and required a wheelchair. As she got older and was completely bedridden, she lost her ability to move and couldn't communicate at all, including pointing, nodding, or even mouthing words. At the core of this interview is Jessica's powerful life philosophy that “joy and sorrow can hold hands.” Says Jess: “Dalia showed me that we can be going through what feels like a horror movie and laugh and create meaning and joy. We tried to have fun in any way we could, and she was leading that charge. She wanted to be a kid, and we were going to give that to her. We all learned that it's okay to laugh, to smile, and to be happy. The joy we created became even more powerful because of the sorrow we had.” Hit that download button as fast as you can. Jessica's story is overflowing with the power of love. www.jessicafeinstories.com #motherhood #rarediseases #resiliency #family.
We're thrilled to welcome back Jaclyn Downs, expert in gene therapy and personalized wellness, for another powerful conversation!This week, Jaclyn dives deep into how your genetic makeup influences anxiety, oxytocin production, endorphins, and depression — and what you can do to support your emotional health naturally. Learn how family predispositions affect your mood, why some people are more prone to anxiety and depression than others, and how understanding your genes can help you create a customized path to greater peace and well-being.If you've ever wondered why emotional ups and downs run in families — or what you can do about it — this episode is a must-listen.Connect with Jaclyn Downs and dive deeper into her work >> here and follow her on Instagram @functionalgenomicsWhat did you think of today's episode?>> Say hello and share your thoughts!Be sure to join the Manifesting Clarity Facebook page where we talk all about the lessons we've learned on the journey thus far and action steps we can take to bring more clarity into our lives! Thank you for listening! We are beyond grateful for you.
Hawk recaps his dinner with the Thursday Dumper himself, the guys talk about how many Genes there are, John Bonnes talks about the surging Minnesota TwinsSee omnystudio.com/listener for privacy information.
Hawk recaps his dinner with the Thursday Dumper himself, the guys talk about how many Genes there are, John Bonnes talks about the surging Minnesota Twins
WATCH REACTION EPISODE ON PATREON: https://www.patreon.com/JulianDorey (***TIMESTAMPS in description below) ~ Ben Lamm is an American serial entrepreneur & billionaire. He is best known for founding Colossal Biosciences with Harvard Geneticist George Church. Colossal utilizes genetic engineering and reproductive technology to attempt the de-extinction of extinct species. They recently recreated genetically modified dire wolves and seek to re-create the Woolly Mammoth in the next 5 years. Matt James is an exotic animal expert, zoologist & Chief Animal Officer of Colossal Biosciences. BEN & MATT's LINKS - Ben IG: https://www.instagram.com/benlamm/?hl=en - Ben X: https://x.com/benlamm?lang=en - Matt IG: https://www.instagram.com/m_walkerj/?locale=en_AE%2B2&hl=en - Colossal YT: https://www.youtube.com/@itiscolossal - Colossal Website: https://colossal.com/ FOLLOW JULIAN DOREY INSTAGRAM (Podcast): https://www.instagram.com/juliandoreypodcast/ INSTAGRAM (Personal): https://www.instagram.com/julianddorey/ X: https://twitter.com/julianddorey JULIAN YT CHANNELS - SUBSCRIBE to Julian Dorey Clips YT: https://www.youtube.com/@juliandoreyclips - SUBSCRIBE to Julian Dorey Daily YT: https://www.youtube.com/@JulianDoreyDaily - SUBSCRIBE to Best of JDP: https://www.youtube.com/@bestofJDP ****TIMESTAMPS**** 0:00 - Intro 1:23 - Paul Rosolie Tape Measure Story 3:24 - The 6th Global Extinction, Restoring Dire Wolf & Woolly Mammoth 13:43 - De-Extinction & Science / Tech Behind It, Red Wolves 23:15 - Rewilding New Species & Effect on Genes, Ancient DNA Coding Breakdown (White Rhino) 30:35 - Northern Quoll Extinction, Jabba the Hutt Toads 35:08 - GMOs are good? 37:24 - How Colossal Makes Money 43:18 - The net value of a Whale, “Jurassic Park” & “I Am Legend” Risk 52:02 - Lab Creation Debate vs Natural / Organic, Chinese Gene-Edited Child Controversy 58:12 - How Matt joined Colossal Biosciences team, $50 Million to Elephant conservation 1:02:00 - How Colossal turned Scientist “Haters” into Supporters & Why, Science “Semantics” 1:09:56 - Colossal Would NOT Exist without AI, Talking to critics 1:14:05 - Working on Extinct Species vs Endangered Species 1:17:06 - Woolly Mouse De-Extinction & How They Did It (EXPOSED) 1:23:59 - Colossal NOT Cloning, How Species are designated, Dire Wolves vs Gray Wolves 1:32:28 - Julian & Ben explain Built-in Media Manipulation of Colossal 1:39:20 - You can't clone a Woolly Mammoth, Colossal's Animal Safety Measures 1:43:15 - How Colossal Edited Dire Wolf Genes 1:47:28 - “Playing God” Debate 1:54:10 - Ben & Matt REACT to Paul Rosolie's Criticism of Colossal 2:04:26 - Artificial Wombs (Ex-Utero) 2:06:28 - Can Colossal Rebuild EVOLUTIONARY Behaviors? (Extinct Elk Example) 2:09:53 - Ben & Matt want to visit Paul Rosolie, Julian remarks on his Amazon Jungle visit 2:11:55 - Colossal's Re-Wilding Plan for Animals, Tasmanian Tiger 2:16:48 - Ben & Matt invite Julian to visit Colossal CREDITS: - Host, Editor & Producer: Julian Dorey - In-Studio Producer: Alessi Allaman - https://www.youtube.com/@UCyLKzv5fKxGmVQg3cMJJzyQ Julian Dorey Podcast Episode 297 - Ben Lamm & Matt James (Colossal Team - Dire Wolf) Music by Artlist.io Learn more about your ad choices. Visit podcastchoices.com/adchoices
[This episode originally aired on May 9, 2023] Buddha nature, or “enlightened genes,” isn't something outside of us that we need to construct or to import • it is a force of awakening that is within us, and it is quite simple and quite natural • it is like the strong determination of children to learn and to develop; it's almost a kind of discontent looking to awaken • traditional texts point to this inherent nature as the root cause of awakening • the second cause of awakening is the pivotal point where that cause from within meets a cause from without—when you meet a teacher or a spiritual friend, someone who recognizes this quality within you and mirrors it back to you • that meeting point is extremely important • the third cause is the confidence that ensues from that meeting point, the confidence and trust in your own nature • the fourth cause is discriminating awareness or wisdom-insight; it is the insight that cuts through the fog and the distractions that cover over our inherent nature • this wisdom cuts through false identities and fixations, disassembling the solid walls of ego that alienate us from our true nature.
En la primera conferencia del ciclo “La vida cotidiana en la antigua Grecia”, la catedrática de Arte Antiguo de la Universidad Autónoma de Madrid, Carmen Sánchez Fernández, explora el punto de vista y los tópicos de las mujeres en la antigua Grecia a partir de las imágenes del arte, donde aparecen representadas en el gineceo y también yendo a la escuela, trabajando o incluso en la palestra, y donde además no falta la presencia de mujeres inquietantes como heteras, ménades o amazonas.Más información de este acto
My HoneyDew this week is comedian Kelsey Cook! Check out her latest special, Mark Your Territory, now available on YouTube and Hulu, and her podcast, Pretend Problems, co-hosted with comedian Chad Daniels. Kelsey joins me in the studio this week to highlight the lowlight of her mother's battle with frontotemporal dementia (FTD). We dive into the emotional and financial rollercoaster of caregiving, and how genetic testing plays a role in shaping future plans. Plus, Kelsey shares what it's like trying to land jokes in the world's saddest room. SUBSCRIBE TO MY YOUTUBE and watch full episodes of The Dew every toozdee! https://youtube.com/@rsickler SUBSCRIBE TO MY PATREON - The HoneyDew with Y'all, where I Highlight the Lowlights with Y'all! Get audio and video of The HoneyDew a day early, ad-free at no additional cost! It's only $5/month! AND we just added a second tier. For a total of $8/month, you get everything from the first tier, PLUS The Wayback a day early, ad-free AND censor free AND extra bonus content you won't see anywhere else! https://www.patreon.com/TheHoneyDew What's your story?? Submit at honeydewpodcast@gmail.com Get Your HoneyDew Gear Today! https://shop.ryansickler.com/ Ringtones Are Available Now! https://www.apple.com/itunes/ http://ryansickler.com/ https://thehoneydewpodcast.com/ SUBSCRIBE TO THE CRABFEAST PODCAST https://podcasts.apple.com/us/podcast/the-crabfeast-with-ryan-sickler-and-jay-larson/id1452403187 SPONSORS: GhostBed -Head to https://www.GhostBed.com/honeydew and use code HONEYDEW to get an extra 10% off your entire order Cure Hydration -Get 20% off your first order! Stay hydrated and feel your best by visiting https://www.curehydration.com/HONEYDEW and using promo code HONEYDEW
In this episode, we sit down with Dr. Matthew Dawson, the founder and CEO of Wild Health, and leader in genomics-based precision medicine. Dr. Matt breaks down what precision medicine truly means--how it goes beyond traditional healthcare to create highly personalized plans based on your unique genetic blueprint and blood work. We explore some of the most important genes to assess for optimizing health, performance, and longevity, including the ApoE gene. He shares powerful insights into the future of medicine and why understanding your genetics is crucial for extending healthspan. Plus, we open up about our own personal Wild Health test results and how they've shaped our individual wellness journey. This conversation is packed with actionable insights you won't want to miss!Dr. Matthew Dawson is the founder and CEO of Wild Health, a genomics-based precision medicine company, and the CEO of TruDiagnostic, an epigenetics testing lab. He has authored two textbooks, published over two dozen studies, lectured in over 20 countries, and won national awards for education and innovation. His passion is unlocking the secrets of the genome and epigenome and using them to optimize health and maximize healthspan. He lives in the woods with his wife, four children, and two dogs.SHOW NOTES: 0:31 Welcome to the show!3:57 Dr. Matt Dawson's Bio4:40 Welcome Dr. Matt to the show!5:14 What is “Precision Medicine”?7:14 Your genes are not your destiny11:09 Renee's experience with Bulletproof coffee11:38 MTHFR & Homocysteine12:43 Combining lab work with genetics17:24 Alzheimer's genetics20:32 What to do for APOE-3/422:56 Biomarkers for optimal health 24:28 Can you change your sleep chronotype?28:26 Genes for telomere length31:37 *ALIGN MAT*33:16 *PIQUE TEA*35:27 Boosting BDNF37:30 Something new about HbA1C!39:47 FOXO3 Gene for Longevity43:40 Blue Zones & social connection45:12 Testing Biological Age49:08 Caloric Restriction for Longevity51:42 The perfect diet for your genes53:25 Comparing macro tolerances57:37 Wild Health reports 59:12 Coming soon for Precision Medicine!1:04:16 His final piece of advice1:04:56 Thanks for tuning in!RESOURCES:Website: wildhealth.com - discount code: BIOHACKERBABESInstagram: wildhealthmdLinkedIn: Wild HealthMy Align Mat - discount code: BIOHACKERBABES to save $250Pique Tea - Save $ with this link!Puori - Save 20% with discount code: BIOHACKERBABESEffecty - Save $50 with discount code: BIOHACKERBABESOur Sponsors:* Check out Effecty and use my code BIOHACKERBABES for a great deal: https://www.effecty.com* Check out Puori: https://Puori.com/BIOHACKERBABESSupport this podcast at — https://redcircle.com/biohacker-babes-podcast/donationsAdvertising Inquiries: https://redcircle.com/brands
Host: Denise M. Dupras, M.D., Ph.D. Guest: Michael Zimmer, Ph.D., Director of Rare Diseases at Moderna Therapeutics This episode of Genes & Your Health welcomes Dr. Michael Zimmer from Moderna Therapeutics, who discusses how mRNA technology is being applied to treat rare genetic diseases, especially liver-based metabolic disorders. Dr. Zimmer explains how mRNA can help the body produce missing proteins, the challenges of delivering these therapies, and the promise they hold for previously untreatable conditions. Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts
We spent five years trying to have a baby and then decided to make the switch from baby making to family making - Jessica Fein We're back in my cozy living room for this episode of The Story Behind Her Success. I'm learning that when you're sitting on a comfy couch with the fire going, the time you spend together feels more like a chat between friends and less like a formal interview. An author, marketing executive, and former opinion columnist for the Boston Globe, Jessica Fein's book, Breath Taking: A Memoir of Family, Dreams and Broken Genes, will give you new reasons to believe in the resiliency of the human spirit. In Part One of this interview, Jessica tells the story of how she and her husband, Rob, spent five years trying to have a baby. When nothing worked, they turned to adoption, and were so overjoyed with their decision, they wondered why they hadn't made it sooner. Over the next few years, the couple welcomed three beautiful babies into their home, all of whom were from Guatemala. It was baby heaven with Jonah, Dalia, and Theo for a while, until the little voice inside Jessica's head got louder and louder. Call it a hunch, or mother's intuition, but Jessica knew that something just wasn't right with Dalia. As a toddler, she fell down a lot, and her speech was delayed. Repeated tests by early intervention experts showed that Dalia was on the lower end of normal, but as time went by, Jessica persisted. Finally, Dalia's hearing was tested and showed moderate hearing loss. Now in kindergarten, Dalia had hearing aids, but continued falling down. Since she was adopted, doctors suggested that Dalia undergo genetic testing, and the result was devastating. Five-year-old Dalia was diagnosed with a degenerative, rare disease with no cure called MERFF, which impacts the ability of the body's organs to function. MERFF is degenerative and has no cure. 2 children in 1 million will get this disease, and Dalia had yet another layer of the disease, making her 1 of only six known cases in the world. With this news, Jessica and her family began a journey filled with overwhelming fear, sorrow, and a belief that in life, we must find reasons to laugh in order to capture joy wherever we can. For a 21-minute story that will leave you breathless, just hit that download button. #rarediseases #motherhood #storytelling #adoption
Are we shaped by our genes or by our environment? For centuries, this question has fueled one of science's most enduring debates. But the truth is more shocking—and more fascinating—than either side ever imagined. Princeton professor Dalton Conley reveals why we need to abandon the idea of "nature vs. nurture" and embrace a radically new understanding of human development.
We know life on Earth wouldn't be possible without the moon. Now scientists are finding the moon might even be influencing our biology on a molecular level. Guest: Rebecca Boyle, science journalist and author of Our Moon: How Earth's celestial companion transformed the planet, guided evolution, and made us who we are For show transcripts, go to vox.com/unxtranscripts For more, go to vox.com/unexplainable And please email us! unexplainable@vox.com We read every email. Support Unexplainable (and get ad-free episodes) by becoming a Vox Member today: vox.com/members Learn more about your ad choices. Visit podcastchoices.com/adchoices