Family of DNA sequences found in prokaryotic organisms
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Episode 9: The Future of Survival – The Genetic Engineering Revolution Episode Description In this episode of The Future of Survival, we explore the rapidly accelerating world of genetic engineering. From CRISPR-edited crops and lab-grown organs to designer babies and enhanced humans, gene editing could change everything about survival. But are preppers ready to embrace a future where survival might be decided by your DNA? We break down the science, the ethical dilemmas, and how to prepare for a biotech-driven world. Episode Breakdown
Featuring Dave Beverley Sr (Jesus Freak Computer Geek), Pete Ohlinger (Days of Noah Podcast), & Dr. Alphonzo Monzo (DrMonzo.com)Join host Rod Smith on the Millennial Mustard Seed Podcast for a riveting exploration into how cutting-edge science and technology intersect with the spiritual realm. In this episode, our distinguished panel dives into the transformative worlds of CRISPR gene editing, Computational Bio, Energy Harvesting Beast Tech, W-Band, and self healing nephilim nano tech are just a few of the wild discussion points on this part two roundtable episode. share this one far and wide friends!Explore the possibility that modern science and technology are playing an unforeseen role in the cosmic battle between light and darkness.• Panel Perspectives: Hear from Dave Beverley Sr, Pete Ohlinger, and Dr. Alphonzo Monzo as they blend scientific insight with a biblical lens, challenging conventional narratives and inspiring deeper faith in Christ.• Plant a seed in time of need: https://creators.spotify.com/pod/show/rodney-jay/subscribe• Email Rod Smith:mmseed@proton.me Partner with Our Ministry: Consider supporting and partnering with us as we spread the Gospel through innovative media.• Buy a Copy of My New Book! https://a.co/d/3Gf5sqK• Venmo:@Rodney-Smith-368• PayPal:@creative775• Cash App:$Rodsworth77
In today's episode, we trace a record-speed rescue of an infant using CRISPR gene editing and weigh the growing calls to freeze the very science that pulled it off.
My guest is Dr. Melissa Ilardo, Ph.D., professor of biomedical informatics at the University of Utah. We discuss the interplay between genes and behaviors, including how certain behaviors can improve resilience by changing gene and organ function, as well as natural selection events happening in humans today. We also discuss the immune system–related reasons people find the smells of potential mates attractive—or not. We explore how physical and psychological traits are passed from one generation to the next, and the specific behaviors that can influence gene expression to improve health and performance. Melissa explains her lab's pioneering research on breath-hold training and how activation of the dive reflex through breath holding can significantly improve oxygen availability by changing spleen size and function. We also delve into the medical uses and ethics of gene editing to cure disease in both babies and adults. For those interested in genes and inheritance, human performance, immune system function, and natural selection, this episode illustrates the remarkable interplay between human nature and nurture. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Joovv: https://joovv.com/huberman Eight Sleep: https://eightsleep.com/huberman LMNT: https://drinklmnt.com/huberman Function: https://functionhealth.com/huberman Timestamps 00:00:00 Melissa Ilardo 00:02:35 Nature vs Nurture, Gene Expression, Eye Color 00:07:06 Sponsors: Joovv & Eight Sleep 00:10:24 Epigenetics, Trauma, Mutations; Hybrid Vigor, Mate Attraction 00:15:47 Globalization; Homo Sapiens, Mating & Evolution; Mutations 00:25:28 Sea Nomads, Bajau & Moken Groups; Free Diving, Dangers & Gasp Reflex 00:32:52 Cultural Traditions, Free Diving & Families; Fishing 00:35:36 Mammalian Dive Reflex, Oxygen, Spleen, Cold Water & Face; Exercise 00:42:43 Sponsors: AG1 & LMNT 00:46:00 Free Diving, Spleen, Thyroid Hormone, Performance Enhancement 00:52:00 Dive Reflex, Immune System; Swimming & Health; Coastal Regions & Genetics 00:55:17 Female Free Divers, Haenyeo, Cold Water, Age, Protein 01:03:20 Human Evolution & Diet, Lactase, Fat 01:05:07 Korean Female Free Divers & Adaptations, Cardiovascular, Pregnancy 01:10:13 Miscarriages & Genetic Selection; Bajau, External Appearance, Mate Selection 01:17:15 Sponsor: Function 01:19:03 Free Diving, Underwater Vision; Super-Performers & Genetics 01:25:01 Cognitive Performance, Autism, Creativity; Genetic Determinism & Mindset 01:36:30 Genetics & Ethics, CRISPR, Embryo Genetic Screening 01:44:36 Admixture, Genetics; Are Humans a Single Species? 01:49:39 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices
Topics discussed on this episode include the benefits of marriage, David Hogg getting the axe, California taking a soft stance on child trafficking, the best frozen pizza, an American basketball player arrested in Indonesia, NFL Draft grades, the NBA Playoffs, genetically modified babies, a robot who attacked its handlers, what David Duchovny thinks about conspiracy theories, and the fantastic story of Indrid Cold.
Broadcast from KSQD, Santa Cruz on 5-22-2025: Dr. Dawn explores groundbreaking cancer research using high-throughput "digital twin" analysis to reverse colon cancer cells back to normal states, identifying three master molecular switches that can induce normal cell differentiation without killing the cancer cells, thus avoiding traditional chemotherapy side effects. She discusses remarkable results from Memorial Sloan Kettering showing 80% of patients with mismatch repair deficient tumors, including all 49 rectal cancer patients, saw complete tumor disappearance after six months of dostarlimab immunotherapy, with no recurrence at five years and minimal side effects. The program covers innovative CRISPR applications, including targeting previously "undruggable" cancer mutations like KRAS and BRAF by selectively degrading mutant RNA messages while preserving healthy genes, offering unprecedented precision in cancer treatment. Dr. Dawn explains a clever immunotherapy approach that disguises tumors as pig organs using Newcastle disease virus carrying alpha-gal enzyme, tricking the immune system into mounting fierce attacks against cancer cells, showing promising results in both monkey and human trials. She describes fascinating research using cryoshocked tumor cells as Trojan horses, where liquid nitrogen-treated cancer cells carrying CRISPR gene editing tools directly seek out tumors, offering superior targeting compared to injecting CRISPR. The show reveals how cancers create protective acid walls around themselves to repel immune cells, with individual cancer cells pumping lactic acid away from the tumor center to form pH 5.3 barriers that kill attacking CD8 T cells within hours. Dr. Dawn discusses breakthrough mRNA cancer vaccines for glioblastoma using patients' own tumor cells, showing rapid immune system activation within 48 hours and extending survival in both dogs and humans with this aggressive brain cancer. She explores the "flower code" mechanism where cancer cells gaslight healthy cells through epigenetic manipulation, expressing dominant "flower win" codes to overpower normal cells expressing "flower lose" codes in biological turf wars. The program addresses systemic problems in cancer classification, explaining how organ-based categorization delays access to effective treatments, with patients waiting years for drugs that could help based on molecular profiles rather than tumor location. Dr. Dawn concludes by highlighting medical discrimination against people with Duffy null phenotype, primarily affecting African Americans, whose naturally lower neutrophil counts lead to reduced chemotherapy doses and excluded clinical trial participation despite no increased infection risk.
Support the show:https://www.paypal.me/Truelifepodcast?locale.x=en_USBuy Grow kit: https://modernmushroomcultivation.com/This Band willl Blow your Mind! Codex Serafini: https://codexserafini.bandcamp.com/album/the-imprecation-of-animaThey bottled dreams and sold illusions.He grew gods in basements.While the world slept on the soil, he listened to its spores.He is the rebel scientist, the culture shifter, the underground alchemist.A pioneer not just of mushrooms—but of meaning.Doma, creator of TidalWave Cubensis, architect of Magic Myco and MycoCoil™,is the visionary behind The Cultivar Cup—where art, science, and soul converge like a mycelial uprising.With one foot in bioscience, one in art & tech,he doesn't just breed mushrooms—he splices destinies, isolates revolutions,and maps the uncharted genetics of psilocybin itself.CRISPR is within reach. HPLC is on the table.And every sterile spore is blessed in the temple of his lab.But no mycelial network thrives alone.Enter Clinton Diong—the architect of connection.CEO of The Fruit of Knowledge and former design engineer,Clinton brings the circuitry of community to the circuitry of consciousness.Where Doma births new strains, Clinton builds new structures—platforms for global collaboration, tools for informed evolution,bridges between law, healing, and the ancient future.Together, they embody two poles of the same electric storm:The underground rebel and the strategic builder.The geneticist and the connector.The mycelium and the mind.This conversation is more than a podcast—it's a sporeprint of the future.Welcome to the future of fungi.Welcome to the movement beneath your feet.Welcome, my friends… Brown Treasure - Premium Island ManureMagicMycoFam - Cultivar Cup, Mushroom TestingThe miraculix QTests - the first drug purity tests - MiraculixAll Things Grow | Cannabis Nursery in Brooklyn | Brooklyn, NY, USAAffiliates — Twisted Tree NurseryGordoTEKOur Story – T.G.Tinctures and Mycology Supplies - Vital Bloom TincturesHamilton's MushroomsBuy Rare Mushroom Spore Syringes – Enigma, Jack Frost, MoreHow to Grow Psychedelic Mushrooms at Home?Home Page - Trip Team Family Support the show:https://www.paypal.me/Truelifepodcast?locale.x=en_USCheck out our YouTube:https://youtube.com/playlist?list=PLPzfOaFtA1hF8UhnuvOQnTgKcIYPI9Ni9&si=Jgg9ATGwzhzdmjkgGrow your own:https://modernmushroomcultivation.com/This Band Will Blow Your Mind: Codex Serafinihttps://codexserafini.bandcamp.com/album/the-imprecation-of-anima
In this episode, Jason chats with David Friedberg—CEO of Ohalo Genetics and co-host of the All-In Podcast—about how AI is transforming agriculture and startups. David introduces Ohalo's "Boosted Breeding" technology, which enables plants to inherit 100% of genes from both parents, potentially doubling crop yields. They also discuss building AI-first companies, genome language models, and the future of creativity in an AI-driven world.*Timestamps:(0:00) David Friedberg joins Jason to discuss AI Basics.(1:44) How AI leveled up hiring and operations at startups(5:46) AI and economic opportunities, complex problem-solving, and leadership's role(11:48) How to build an AI-first company culture(16:48) AI's transformative impact on biology and DNA sequencing(21:36) The “GLM” - GPT for DNA Is already in production(23:17) Biology meets AI: designing perfect plants with CRISPR and genome models(32:08) Is the “Age of Abundance” around the corner?(35:56) Democratization of creativity through AI: personalized Star Wars musicals & the future of media*Uncover more valuable insights from AI leaders in Google Cloud's 'Future of AI: Perspectives for Startups' report. Discover what 23 AI industry leaders think about the future of AI—and how it impacts your business. Read their perspectives here: https://goo.gle/futureofai*Check out all of the Startup Basics episodes here: https://thisweekinstartups.com/basicsCheck out Google Cloud: https://cloud.google.com/Check out Ohalo: https://www.ohalo.com/*Follow David:X: https://x.com/friedbergLinkedIn: https://www.linkedin.com/in/davidfriedberg/*Follow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanis*Follow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.com
00:03:50 - 00:18:12Trump's $175 billion Golden Dome missile defense system aims to use space-based interceptors to counter advanced missiles, but China warns it risks militarizing space and sparking an arms race. Congress estimates costs at $500 billion over 20 years. Russia's nuclear-powered Burevestnik missile, with unlimited range, could render it obsolete, raising concerns about budget overruns and SpaceX's involvement. 00:18:36 - 00:26:10Neocons push for war with Iran, demanding its nuclear program's dismantlement, while MAGA influencers like Bannon and Greene favor diplomacy. This reflects public exhaustion with Middle East wars, opposing defense contractors' agendas, with the host noting a hopeful shift against escalation. 00:31:12 - 00:38:12The Pentagon, citing unverified Chinese “super soldier” claims, proposes genetic experiments on U.S. troops using CRISPR and mRNA, alongside biosurveillance. Ethical concerns arise over human experimentation and CIA ties, with deregulation favoring biotech firms, risking taxpayer funds and safety. 00:44:45 - 00:53:36Trump grants asylum to 54 Afrikaner South Africans facing violence and land confiscation, confronting Ramaphosa with evidence of “white genocide.” The host supports this, criticizing media deflections and narrow refugee definitions, emphasizing the severe persecution Afrikaners endure. 01:17:37 - 01:36:07The FDA now requires trials for COVID-19 vaccines for healthy people aged 6 months to 64, but approved high-risk group vaccines without data, rushed by Trump's “warp speed.” A Senate report reveals Biden officials hid myocarditis risks in young men, delaying warnings despite early signals, driven by corporate interests. Low vaccine uptake (13% kids, 23% adults) and rising heart issues highlight the cover-up. 01:36:07 - 01:40:50Medpage Today confirms RFK Jr.'s claim that the MMR mumps vaccine is ineffective, admitting Merck's fraudulent data, but dismisses him as a lawyer. Failed lawsuits left untested, harmful vaccines on the market, with one-third of trial kids facing health issues, exposing systemic vaccine regulation flaws. 01:48:10 - 02:01:35A bill strips states' AI regulation rights for 10 years, a Trump-backed federal power grab seen as unconstitutional. States urged to block AI infrastructure. Vermont pauses its EV mandate, citing weak tech and infrastructure, resisting California's 2035 EV push, which could set a national standard. 02:04:03 - 02:08:48Rep. Luna's bill seeks to repeal the Patriot Act, blamed for post-9/11 surveillance and rights violations. The host sees 9/11 as a pretext for wars and a police state, urging the act's end to curb intelligence agency abuses and restore privacy. 02:10:21 - 02:34:23Cecile Richards, dead at 67 from brain cancer, is condemned for leading 3.5 million abortions at Planned Parenthood and alleged fetal part sales. Her unrepentant stance, Freedom from Religion awards, and Biden's Medal of Freedom are criticized as anti-God. Kushner's 2017 funding offer was rejected. Abortion's 2024 toll (45.1 million, 42% of deaths) and 60% of African American deaths are called “black genocide.” GOP's funding via CARES Act ($80 million) and MAGA's defense of Trump's vaccines are slammed. 02:37:05 - 02:49:03Brown Foods' “Unreal Milk” and Israeli lab-grown dairy, like Wilk, claim to cut emissions by 82%, backed by Gates and USDA despite no farming. Biomilq targets infants, tied to C40's no-dairy push. Called “tumor milk,” it's criticized as an anti-agriculture, climate-driven scam with lax FDA oversight. 02:50:39 - 03:00:36Trump's “Gold Card” visa, costing $5 million, claims 250,000 applicants to raise $1 trillion, but only 277,000 global millionaires qualify. Offering tax-free foreign income and no country caps, it's decried as a corrupt deal for Trump's allies, bypassing vetting and America-first values.Follow the show on Kick and watch live every weekday 9:00am EST – 12:00pm EST https://kick.com/davidknightshow Money should have intrinsic value AND transactional privacy: Go to https://davidknight.gold/ for great deals on physical gold/silver For 10% off Gerald Celente's prescient Trends Journal, go to https://trendsjournal.com/ and enter the code KNIGHT Find out more about the show and where you can watch it at TheDavidKnightShow.comIf you would like to support the show and our family please consider subscribing monthly here: SubscribeStar https://www.subscribestar.com/the-david-knight-showOr you can send a donation throughMail: David Knight POB 994 Kodak, TN 37764Zelle: @DavidKnightShow@protonmail.comCash App at: $davidknightshowBTC to: bc1qkuec29hkuye4xse9unh7nptvu3y9qmv24vanh7Become a supporter of this podcast: https://www.spreaker.com/podcast/the-david-knight-show--2653468/support.
00:03:50 - 00:18:12Trump's $175 billion Golden Dome missile defense system aims to use space-based interceptors to counter advanced missiles, but China warns it risks militarizing space and sparking an arms race. Congress estimates costs at $500 billion over 20 years. Russia's nuclear-powered Burevestnik missile, with unlimited range, could render it obsolete, raising concerns about budget overruns and SpaceX's involvement. 00:18:36 - 00:26:10Neocons push for war with Iran, demanding its nuclear program's dismantlement, while MAGA influencers like Bannon and Greene favor diplomacy. This reflects public exhaustion with Middle East wars, opposing defense contractors' agendas, with the host noting a hopeful shift against escalation. 00:31:12 - 00:38:12The Pentagon, citing unverified Chinese “super soldier” claims, proposes genetic experiments on U.S. troops using CRISPR and mRNA, alongside biosurveillance. Ethical concerns arise over human experimentation and CIA ties, with deregulation favoring biotech firms, risking taxpayer funds and safety. 00:44:45 - 00:53:36Trump grants asylum to 54 Afrikaner South Africans facing violence and land confiscation, confronting Ramaphosa with evidence of “white genocide.” The host supports this, criticizing media deflections and narrow refugee definitions, emphasizing the severe persecution Afrikaners endure. 01:17:37 - 01:36:07The FDA now requires trials for COVID-19 vaccines for healthy people aged 6 months to 64, but approved high-risk group vaccines without data, rushed by Trump's “warp speed.” A Senate report reveals Biden officials hid myocarditis risks in young men, delaying warnings despite early signals, driven by corporate interests. Low vaccine uptake (13% kids, 23% adults) and rising heart issues highlight the cover-up. 01:36:07 - 01:40:50Medpage Today confirms RFK Jr.'s claim that the MMR mumps vaccine is ineffective, admitting Merck's fraudulent data, but dismisses him as a lawyer. Failed lawsuits left untested, harmful vaccines on the market, with one-third of trial kids facing health issues, exposing systemic vaccine regulation flaws. 01:48:10 - 02:01:35A bill strips states' AI regulation rights for 10 years, a Trump-backed federal power grab seen as unconstitutional. States urged to block AI infrastructure. Vermont pauses its EV mandate, citing weak tech and infrastructure, resisting California's 2035 EV push, which could set a national standard. 02:04:03 - 02:08:48Rep. Luna's bill seeks to repeal the Patriot Act, blamed for post-9/11 surveillance and rights violations. The host sees 9/11 as a pretext for wars and a police state, urging the act's end to curb intelligence agency abuses and restore privacy. 02:10:21 - 02:34:23Cecile Richards, dead at 67 from brain cancer, is condemned for leading 3.5 million abortions at Planned Parenthood and alleged fetal part sales. Her unrepentant stance, Freedom from Religion awards, and Biden's Medal of Freedom are criticized as anti-God. Kushner's 2017 funding offer was rejected. Abortion's 2024 toll (45.1 million, 42% of deaths) and 60% of African American deaths are called “black genocide.” GOP's funding via CARES Act ($80 million) and MAGA's defense of Trump's vaccines are slammed. 02:37:05 - 02:49:03Brown Foods' “Unreal Milk” and Israeli lab-grown dairy, like Wilk, claim to cut emissions by 82%, backed by Gates and USDA despite no farming. Biomilq targets infants, tied to C40's no-dairy push. Called “tumor milk,” it's criticized as an anti-agriculture, climate-driven scam with lax FDA oversight. 02:50:39 - 03:00:36Trump's “Gold Card” visa, costing $5 million, claims 250,000 applicants to raise $1 trillion, but only 277,000 global millionaires qualify. Offering tax-free foreign income and no country caps, it's decried as a corrupt deal for Trump's allies, bypassing vetting and America-first values.Follow the show on Kick and watch live every weekday 9:00am EST – 12:00pm EST https://kick.com/davidknightshow Money should have intrinsic value AND transactional privacy: Go to https://davidknight.gold/ for great deals on physical gold/silver For 10% off Gerald Celente's prescient Trends Journal, go to https://trendsjournal.com/ and enter the code KNIGHT Find out more about the show and where you can watch it at TheDavidKnightShow.comIf you would like to support the show and our family please consider subscribing monthly here: SubscribeStar https://www.subscribestar.com/the-david-knight-showOr you can send a donation throughMail: David Knight POB 994 Kodak, TN 37764Zelle: @DavidKnightShow@protonmail.comCash App at: $davidknightshowBTC to: bc1qkuec29hkuye4xse9unh7nptvu3y9qmv24vanh7Become a supporter of this podcast: https://www.spreaker.com/podcast/the-real-david-knight-show--5282736/support.
In this episode of the Epigenetics Podcast, we talked with Ani Deshpande from Sanford Burnham Prebys about his work on epigenetic regulation and developing small molecules through high throughput screens for AML. Throughout our discussion, we delve into Dr. Despande's journey into the field of biology and science, tracing his evolution from a literature enthusiast in Mumbai to a dedicated cancer researcher. He reflects on his formative experiences during his PhD at Ludwig Maximilian University in Munich, where she developed murine models for refractory acute myeloid leukemia (AML). We examine these models' contributions to therapeutic discovery and understanding the intricate mechanisms underscoring AML's complexities. Transitioning to his postdoctoral work at Scott Armstrong's lab in Boston, Dr. Despande shares his insights on the importance of epigenetic regulators, such as DOT1L, in leukemias, and how they can serve as strategic therapeutic targets. His ambitious pursuit of translational research is further highlighted through his efforts in developing a conditional knockout mouse model and his collaborative work utilizing CRISPR technology to refine our understanding of epigenetic regulation in cancer pathogenesis. Moreover, we engage in a conversation about the challenges and opportunities that arise when establishing his lab at Sanford Burnham Prebys. Dr. Despande candidly discusses the delicate balance between pursuing topics of genuine interest versus adhering to grant fundability, underlining the tension researchers face in the current scientific landscape. His emphasis on the critical need for innovation within lab settings serves as a motivational call for emerging scientists to venture beyond the established templates that often inhibit groundbreaking discoveries. We conclude our dialogue with an exploration of his recent projects, which involve targeting specific epigenetic modifiers and how his lab's findings can contribute to greater understanding and potential treatments for not only AML but also other pediatric cancers driven by gene fusions. Dr. Despande's insights into the integration of modern technologies, such as CRISPR libraries, exemplify his commitment to pushing the boundaries of cancer research. In addition to discussing his scientific contributions, we touch upon Dr. Despande's foray into podcasting (The Discovery Dialogues), shedding light on his motivation to bridge the communication gap between scientists and the broader public. He articulates his desire to demystify scientific discoveries and promote awareness about the intricate journey of research that lays the groundwork for medical advancements. This multidimensional discussion not only highlights his scientific achievements but also emphasizes the importance of effective science communication in fostering public understanding and appreciation of research. References Deshpande AJ, Cusan M, Rawat VP, Reuter H, Krause A, Pott C, Quintanilla-Martinez L, Kakadia P, Kuchenbauer F, Ahmed F, Delabesse E, Hahn M, Lichter P, Kneba M, Hiddemann W, Macintyre E, Mecucci C, Ludwig WD, Humphries RK, Bohlander SK, Feuring-Buske M, Buske C. Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia. Cancer Cell. 2006 Nov;10(5):363-74. doi: 10.1016/j.ccr.2006.08.023. PMID: 17097559. Deshpande AJ, Deshpande A, Sinha AU, Chen L, Chang J, Cihan A, Fazio M, Chen CW, Zhu N, Koche R, Dzhekieva L, Ibáñez G, Dias S, Banka D, Krivtsov A, Luo M, Roeder RG, Bradner JE, Bernt KM, Armstrong SA. AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes. Cancer Cell. 2014 Dec 8;26(6):896-908. doi: 10.1016/j.ccell.2014.10.009. Epub 2014 Nov 20. PMID: 25464900; PMCID: PMC4291116. Sinha S, Barbosa K, Cheng K, Leiserson MDM, Jain P, Deshpande A, Wilson DM 3rd, Ryan BM, Luo J, Ronai ZA, Lee JS, Deshpande AJ, Ruppin E. A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing. Nat Commun. 2021 Nov 11;12(1):6512. doi: 10.1038/s41467-021-26788-6. Erratum in: Nat Commun. 2022 May 16;13(1):2828. doi: 10.1038/s41467-022-30475-5. PMID: 34764240; PMCID: PMC8586238. Related Episodes Targeting COMPASS to Cure Childhood Leukemia (Ali Shilatifard) The Menin-MLL Complex and Small Molecule Inhibitors (Yadira Soto-Feliciano) MLL Proteins in Mixed-Lineage Leukemia (Yali Dou) Contact Epigenetics Podcast on Mastodon Epigenetics Podcast on Bluesky Dr. Stefan Dillinger on LinkedIn Active Motif on LinkedIn Active Motif on Bluesky Email: podcast@activemotif.com
Howie and Harlan are joined by Rebekah Gee, founder and CEO of Nest Health, which provides in-home care to kids on Medicaid and their families. Harlan reports on the first personalized CRISPR gene therapy for a rare genetic disease; Howie untangles the FDA's restrictions on the COVID-19 booster and what it will mean for your ability to get a shot this fall. Links: A Breakthrough CRISPR Treatment “Baby Is Healed With World's First Personalized Gene-Editing Treatment” “Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease” “Progress in the Development of N-of-1 Therapy” “Personalized Gene Editing to Treat an Inborn Error of Metabolism” Nest Health Health & Veritas Episode 40: Rebekah Gee: Can We Bring Family Healthcare to the Home? Nest Health “Nest Health picks up $4M in seed extension funding to build out at-home primary care for families” “How Nest Health Is Redefining Primary Care for Families” Rebekah Gee on LinkedIn on Nest Health “What ‘patient-centered‘ should mean: confessions of an extremist” “Prevalence and Variation of Developmental Screening and Surveillance in Early Childhood” “Postpartum health is in crisis” “The Impact of the Pandemic on Well-Child Visits for Children Enrolled in Medicaid and CHIP” “Families often have chief medical officers—and they're almost always women” “Case Study: Louisiana's Poor Rankings Make Improving Birth Outcomes a State Imperative” “In 6-to-3 Ruling, Supreme Court Ends Nearly 50 Years of Abortion Rights” Rebekah Gee on LinkedIn on Medicaid cuts “5 Key Facts About Medicaid Work Requirements” “Health Provisions in the 2025 Federal Budget Reconciliation Bill” A New COVID Booster Policy “An Evidence-Based Approach to Covid-19 Vaccination” “FDA will limit Covid vaccines to people over 65 or at high risk of serious illness, leaders say” “FDA tightens requirements for COVID vaccine, adding trials for healthy adults” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.
00:45 Treating mosquitoes for malariaResearchers have developed two compounds that can kill malaria-causing parasites within mosquitoes, an approach they hope could help reduce transmission of the disease. The team showed that these compounds can be embedded into the plastics used to make bed nets, providing an alternative to insecticide-based malaria-control measures, which are losing efficacy in the face of increased resistance.Research article: Probst et al.10:42 Research HighlightsThe sunlight-powered device that can harvest drinkable water from desert air, and evidence that the world's richest people are disproportionately responsible for climate impacts.Research Highlight: Atacama sunshine helps to pull water from thin airResearch Highlight: The world's richest people have an outsized role in climate extremes13:02 The genetics that can lead to pregnancy lossResearchers have found specific genetic mutations that can lead to pregnancy loss. It's known that errors, such as the duplication of chromosomes, can lead to nonviable pregnancies but less has been known about non-chromosomal genetic errors. The new work identifies DNA sequence changes that can lead to a non-viable pregnancy. This may offer clinicians the ability to screen embryos for these changes to help avoid pregnancy loss.Research article: Arnadottir et al.22:24 Briefing ChatBespoke CRISPR-based therapy treats baby boy with devastating genetic disease, and the ‘anti-spice' compounds that can lower chillies' heat.Nature: World's first personalized CRISPR therapy given to baby with genetic diseaseNew Scientist: Chemists discover 'anti-spice' that could make chilli peppers less hotSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday. Hosted on Acast. See acast.com/privacy for more information.
What does it really take to bring cutting-edge science out of the lab and into the world? In this episode of Inside Biotech, we sit down with Elizabeth Chabe, founder and CEO of High Touch Group, a strategic marketing firm specializing in biotech, medtech, and deep tech.Elizabeth shares her unique journey—from working in a structural engineering lab and helping scale pilot manufacturing projects, to becoming a trusted advisor to venture-backed startups across the life sciences. Along the way, she's led national campaigns at institutions like The Jackson Laboratory, helped scientists secure critical funding, and built a business that helps translate complex science into commercial success.Whether you're a researcher, founder, or science communicator, Elizabeth offers actionable advice on how to make sure your innovation doesn't stay hidden in the lab. Follow our Instagram @insidebiotech for updates about episodes and upcoming guests! To learn more about BCLA's events and consulting visit our website.Follow BCLA on LinkedIn
Tomatoes come in all kinds of colors, sizes, and flavors. But what's going on at the genetic level? What makes a tomato red or yellow? Tiny or giant?Researchers are mapping the genomes of 22 varieties of nightshades—the family of plants that includes tomatoes, potatoes, and eggplants. They located the genes that control the size of tomatoes and eggplants and then used CRISPR gene editing to grow bigger fruits without sacrificing flavor.Geneticist Michael Schatz joins Host Ira Flatow to talk about his latest research into nightshade genomes and the current state of genetically modified crops.Guest: Dr. Michael Schatz, professor of computational biology and oncology at Johns Hopkins University, based in Baltimore, Maryland.Transcript will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
BestPodcastintheMetaverse.com Canary Cry News Talk #842 - 05.19.2025 - Recorded Live to 1s and 0s CRISPR BABY USA | Comey Calculus, Harry Legs Drama, Nephilim Update Deconstructing World Events from a Biblical Worldview Declaring Jesus as Lord amidst the Fifth Generation War! CageRattlerCoffee.com SD/TC email Ike for discount Join the Canary Cry Roundtable This Episode was Produced By: Executive Producers Sir LX Protocol V2 Baron of the Berrean Protocol*** Sir Jamey Not the Lanister*** Producers of TREASURE (CanaryCry.Support) Sir Darrin Knight of the Hungry Panda's, Julie S, Joel, Aaron B, American Hobo, Cage Rattler Coffee, Lane, Anonymous, Sir Morv Knight of the Burning Chariots Producers of TALENT JOLMS, Sir Thorsteen, Sir Ike, Samurai Princess Producers of TIME Timestampers: Jade Bouncerson, Morgan E Clippy Team: Courtney S, JOLMS, Kristen Reminders: Clankoniphius Links: JAM SHOW NOTES/TIMESTAMPS HELLO WORLD 0:26 EFNO FBI 1:14 →Trump says Comey called for ‘assassination of the president' with '8647′ Instagram post (CNBC) SHILLZILLA Clip: ‘It's So Dumb': Chris Cillizza Unloads On Comey Over Post (Daily Caller) → EPSTEIN Clip: Patel and Bongino say Epstein killed himself “I've seen the whole file” EXECS 30:42 HARRY LEGS JOE 43:13 Exclusive: Prosecutor's audio shows Biden's memory lapses (Axios) → Joe Biden diagnosed with 'aggressive' prostate cancer (BBC) Biden posts about cancer (X) Joe biden Gaffe Cancer 2022 (X) CRISPR 56:10 A Baby Received a Custom Crispr Treatment in Record Time (Wired) Dr. He's Wife (X) AI 1:38:34 Ai will double human lifespan by 2030 (Pop Mechanics) PRODUCERS 1:39:55 NEPHILIM UPDATE 1:56:42 The otherworldly story of goth mystics Fields Of The Nephilim (Louder Sound) PRODUCERS 2:17:44 TALENT/MEET UP 2:17:57 TIME/END 2:37:44
The Rollup TV presents: Mammoth May.The Rollup TV is brought to you by:Celestia: https://celestia.org/Boundless: https://beboundless.xyz/AltLayer: https://www.altlayer.io/Mantle: https://www.mantle.xyz/Omni Network: https://omni.network/Vertex: https://vertexprotocol.com/Frax: https://frax.com/Join The Rollup Family:Website: https://therollup.co/Spotify: https://open.spotify.com/show/1P6ZeYd..Podcast: https://therollup.co/category/podcastFollow us on X: https://www.x.com/therollupcoFollow Rob on X: https://www.x.com/robbie_rollupFollow Andy on X: https://www.x.com/ayyyeandyJoin our TG group: https://t.me/+8ARkR_YZixE5YjBhThe Rollup Disclosures: https://therollup.co/the-rollup-discl
Dana Foss and Ross Wilson are the cofounders of Editpep, a biotech startup focused on developing CRISPR-based therapeutics. They are using a proprietary peptide-based delivery platform that enables targeted delivery to specific cell types, particularly for hard-to-reach areas like the brain. While Dana Foss is the CEO, Ross Wilson is also an Assistant Adjunct Professor of Molecular and Cell Biology and also the Director of Therapeutic Delivery at the Innovative Genomics Institute at the University of California, Berkeley. He is one of those very few academics that co-founded a startup and is very active in building Editpep. Ross explains how he does it all so well! Dana was previously a postdoc in Ross Wilson's lab, where she developed the technology. Ross was a postdoc in Nobel Laureate Jennifer Doudna's lab. Now he has his own lab and collaborates with Jennifer Doudna at the Innovative Genomics Institute. In this episode of lab to startup, we will explore their initial decisions that lead to launching the startup; existing CRISPR delivery technologies, their challenges, and then do a deep dive into their delivery technology. opportunities,; fundraising efforts, and their future goals. Shownotes https://www.editpep.bio/ CRISPR Delivery problem and current solutions Existing solutions like AV, LNPs are mostly limited to mice Ribonucleoprotein, a complex of RNA and protein (RNP): Technology deep dive Outsiders bringing in fresh perspective Dana transitioning out of academia: working on a shared goal Hard to shepard the technology towards the patient by depending on a third party Self motivation and gumption: Ways to move technologies out of the lab Early stage co-founder chemistry Ross's innovative role being an academic and entrepreneur Fundraising journey Open mindedness to non-traditional investors Investors: Berkeley Skydeck, Lindonlight Collective Filters for selecting investors Getting to market: Parallels from other delivery companies like Alnylam Counterintuitive decisions Future goals Connecting the dots
Sunday May 18, 2025. Week 21 Show notes on the site: https://curesyngap1.org/podcasts/syngap10/ CAMP4 Press Release https://investors.camp4tx.com/news-releases/news-release-details/camp4-presents-translational-data-syngap1-related-disorders Dr. Yuri at WODC: https://www.youtube.com/watch?v=oNwgo7TmrVo Presentation at ASGCT: https://investors.camp4tx.com/news-events/presentations GETA Talk: https://www.facebook.com/Syngapresearch/posts/pfbid08Aztex32vdwNZduVkPQeG353W49Dhq8iKJeZEkajKUmkeUiDdCwzyqa9ndEVpdCUl To get these Therapies to kids the NHS data is key, ProMMis CHOP - Email them ENDD@chop.edu Stanford (Singed!) - https://curesyngap1.org/blog/srf-announces-stanford-launches-california-synaptopathy-clinic/ CHCO - https://curesyngap1.org/blog/visiting-syngap1-natural-history-study-childrens-hospital-colorado-chco/ Citizen Health https://cureSYNGAP1.org/Citizen is at 267, why not 300? Hopkins article featuring SRF - Competition is good for the patient FB https://www.facebook.com/cureSYNGAP1/posts/pfbid07MP7St3zdxLKYXTJULKa5S35YvgL6AJndenHicedxU3rtQF6iY1wwwNUoDuUD9cpl LI https://www.linkedin.com/posts/curesyngap1_nih-cuts-stalling-progress-on-rare-genetic-activity-7328449817074946048-AAsB ASGCT Mouse poster for Q504X from the JAX, Dr. Matt Simon Conf Video https://www.youtube.com/watch?v=loYXkkTSUIY Presentation on AAV for SYNGAP1 at Allen by Dr. Megan Quinlan What about this guy? Gift link: https://www.nytimes.com/2025/05/15/health/gene-editing-personalized-rare-disorders.html?unlocked_article_code=1.H08.E-oX.t5bo6kxJGUOU&smid=url-share PBS: https://www.youtube.com/watch?v=dOeiPoa3gvM Eric Topol: https://erictopol.substack.com/p/the-first-human-to-undergo-in-vivo More incredible news https://news.unl.edu/article/husker-team-wins-second-round-prize-in-nih-gene-editing-challenge REPURPOSING Mike's post in private SRF Group: https://www.facebook.com/groups/syngap #Amlexanox with Fortuity Pharma. https://fortuitypharma.com/ Butyrate Update https://aesnet.org/abstractslisting/phenylbutyrate-for-syngap1-related-developmental-and-epileptic-encephalopathy Trial ending at year end, working with SLC6A1 and Rachel Heilmann to continue coverage, then we can scale, once we have a paper. SunButyrate https://a.co/d/7kiHXS8 PUBMED 328 total with 20 YTD https://pubmed.ncbi.nlm.nih.gov/?term=syngap1&sort=date&sort_order=asc&timeline=expanded Sleep https://www.sciencedirect.com/science/article/abs/pii/S1389945724005793?via%3Dihub SRF Fundraisers MDBR with AJH and HM https://curesyngap1.org/calendar/million-dollar-bike-ride-2025/ Well done to Tavilla and Jones! We are over $221k Tavilla clears $160k for Sprint. https://donate.curesyngap1.org/campaign/sprint4syngap2025/c660255 Porter Jones and his friends William, Patrick, and Judson raised over $10k in doughnuts, this netted over $8k because people donated. Amazing and thank you to Krispy Kreme. https://donate.curesyngap1.org/event/sweets-for-syngap1/e678677 SRF PROFILES Vicky post in Mexico https://www.linkedin.com/posts/victoria-arteaga-26913433_diagnostico-epilepsia-syngap1-activity-7329725268003069953-R41P Vicky's Siblings Violeta and Lourdes, sisters to Amelia https://curesyngap1.org/syngap-siblings/ Harper Albrecht Wednesday Warrior #215 parents Ashley and Justin https://cureSYNGAP1.org/Warrior PREREGISTER FOR THE CURE SYNGAP1 CONFERENCE https://curesyngap1.org/calendar/cure-syngap1-conference-2025-hosted-by-srf/
It Happened To Me: A Rare Disease and Medical Challenges Podcast
In this powerful episode of It Happened To Me, co-hosts Cathy Gildenhorn and Beth Glassman are joined by two fierce patient advocates and changemakers in the sickle cell disease community: Wunmi Bakare and Dima Hendricks. Both women are living with sickle cell disease and have transformed their lived experiences into platforms for storytelling, education, and change. They are also the co-hosts of #ThroughTheGenes, a podcast that launched last year on World Sickle Cell Day (June 19, 2024). The show explores gene therapy and other innovative treatments for sickle cell disease while centering patient voices. With a second season debuting again on June 19th (exactly a month from today!), Wunmi and Dima continue to bring much-needed visibility to a condition that is often misunderstood and underfunded. And they will be joined by a new dynamic host, Christelle Salomon! Topics Discussed: What is sickle cell disease and how it impacts daily life The emotional and physical toll of living with a chronic, invisible illness Medical gaslighting and how to advocate for yourself Finding community and realizing you're not alone Blending identity, advocacy, and creativity in the public eye Insights into gene therapy, including CRISPR technology and treatment considerations Health equity and why access to care must be a priority in the sickle cell space The power of patient-centered storytelling through #ThroughTheGenes podcast During the episode Beth referenced a previous episode with someone who has pancreatic cancer, you can listen to Leslie Waldman's full interview on Episode 25 here. Catch up with all of season 1 of #ThroughTheGenes podcast right now, before season 2 launches on World Sickle Cell Day on June 19th, 2025. Both podcasts, It Happened To Me and #ThroughTheGenes are part of Gene Pool Media, the science podcast network. Be sure to check out all these science shows, many of which discuss medical challenges. Stay tuned for the next new episode of “It Happened To Me”! In the meantime, you can listen to our previous episodes on Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “It Happened To Me”. “It Happened To Me” is created and hosted by Cathy Gildenhorn and Beth Glassman. DNA Today's Kira Dineen is our executive producer and marketing lead. Amanda Andreoli is our associate producer. Ashlyn Enokian is our graphic designer. See what else we are up to on Twitter, Instagram, Facebook, YouTube and our website, ItHappenedToMePod.com. Questions/inquiries can be sent to ItHappenedToMePod@gmail.com.
¿Reviviendo especies extintas? La ciencia lo ha logrado: el lobo terrible (Dire wolf) ha sido traído de vuelta a la vida mediante avanzadas técnicas de ingeniería genética y edición de ADN. En este video te contamos todo sobre el revolucionario proyecto de desextinción de Colossal Biosciences, cómo fue posible y qué consecuencias podría tener para la biodiversidad, la ética científica y el equilibrio ecológico.
En los yacimientos arqueológicos encontramos restos humanos y animales, herramientas y objetos de todo tipo, restos de hogueras con alimentos cocinados… Pero, ¿cómo vivieron aquellos individuos? ¿Cómo fabricaron y emplearon esos artefactos? ¿Cómo descuartizaron sus presas? ¿A qué olían las chozas que los cobijaron? La arqueología experimental permite acercarnos al modo de vida de nuestros ancestros e interpretar los hallazgos arqueológicos con mayor precisión. Hemos entrevistado a Javier Baena Preysler, catedrático de Prehistoria y director del Laboratorio de Arqueología Experimental de la Universidad Autónoma de Madrid.En 2010, la expedición Malaspina circunnavegó el planeta a bordo del buque oceanográfico Hespérides y obtuvo una cantidad ingente de datos genéticos microbianos. Gracias a ellos, Ana Lozano del Campo nos ha contado que investigadores españoles han desarrollado dos nuevas 'tijeras' de edición genética CRISPR. Con testimonios de Julián Cerón, del Instituto de Investigación Biomédica de Bellvitge (IDIBELL), y Silvia Acinas, del Instituto de Ciencias del Mar del CSIC. Con Javier Cacho hemos recordado el rescate en 2002 del buque mercante alemán Magdalena Oldendorff, atrapado en los hielos de la Antártida. 28 años después de la clonación de la oveja Dolly, una de las principales aplicaciones de aquella técnica ha sido la clonación de mascotas, especialmente de perros. Algo que, como nos ha comentado Lluís Montoliu, es un proceso caro, ineficiente y éticamente controvertido. Eulalia Pérez Sedeño ha trazado la biografía de Leonor Ferrer Girabau, la primera mujer en conseguir el título de delineante en España en 1905. Durante 33 años trabajó en Barcelona como jefa de delineación en varias compañías telefónicas. Nos dejó un archivo personal que recoge su activismo en la educación, la emancipación y la presencia de la mujer en todos los ámbitos de la sociedad.Escuchar audio
A Gene-Editing Breakthrough Saves Infant With Rare Disease Please Subscribe + Rate & Review KMJ’s Afternoon Drive with Philip Teresi & E. Curtis Johnson wherever you listen! --- KMJ’s Afternoon Drive with Philip Teresi & E. Curtis Johnson is available on the KMJNOW app, Apple Podcasts, Spotify, Amazon Music or wherever else you listen. --- Philip Teresi & E. Curtis Johnson – KMJ’s Afternoon Drive Weekdays 2-6 PM Pacific on News/Talk 580 & 105.9 KMJ DriveKMJ.com | Podcast | Facebook | X | Instagram --- Everything KMJ: kmjnow.com | Streaming | Podcasts | Facebook | X | Instagram See omnystudio.com/listener for privacy information.
Russia-Ukraine delegations meet for the first time since 2022, Donald Trump secures $2 trillion in Gulf state deals, An al-Qaeda affiliate claims the killing of 200 Burkina Faso soldiers in a major attack, Albania declines Kier Starmer's migrant return hub proposal, A BBC report claims that Iran is leveraging organized crime for attacks abroad, An ex-FBI boss is investigated over a post alleged to be a Trump death threat, The FBI will be vacating the J. Edgar Hoover building in Washington, D.C., xAI says an unauthorized change made Grok push South Africa genocide claims, Papua New Guinea declares a polio emergency, and custom CRISPR gene therapy saves a Pennsylvania baby with a rare disease. Sources: www.verity.news
En los yacimientos arqueológicos encontramos restos humanos y animales, herramientas y objetos de todo tipo, restos de hogueras con alimentos cocinados… Pero, ¿cómo vivieron aquellos individuos? ¿Cómo fabricaron y emplearon esos artefactos? ¿Cómo descuartizaron sus presas? ¿A qué olían las chozas que los cobijaron? La arqueología experimental permite acercarnos al modo de vida de nuestros ancestros e interpretar los hallazgos arqueológicos con mayor precisión. Hemos entrevistado a Javier Baena Preysler, catedrático de Prehistoria y director del Laboratorio de Arqueología Experimental de la Universidad Autónoma de Madrid.En 2010, la expedición Malaspina circunnavegó el planeta a bordo del buque oceanográfico Hespérides y obtuvo una cantidad ingente de datos genéticos microbianos. Gracias a ellos, Ana Lozano del Campo nos ha contado que investigadores españoles han desarrollado dos nuevas 'tijeras' de edición genética CRISPR. Con testimonios de Julián Cerón, del Instituto de Investigación Biomédica de Bellvitge (IDIBELL), y Silvia Acinas, del Instituto de Ciencias del Mar del CSIC. Con Javier Cacho hemos recordado el rescate en 2002 del buque mercante alemán Magdalena Oldendorff, atrapado en los hielos de la Antártida. 28 años después de la clonación de la oveja Dolly, una de las principales aplicaciones de aquella técnica ha sido la clonación de mascotas, especialmente de perros. Algo que, como nos ha comentado Lluís Montoliu, es un proceso caro, ineficiente y éticamente controvertido. Eulalia Pérez Sedeño ha trazado la biografía de Leonor Ferrer Girabau, la primera mujer en conseguir el título de delineante en España en 1905. Durante 33 años trabajó en Barcelona como jefa de delineación en varias compañías telefónicas. Nos dejó un archivo personal que recoge su activismo en la educación, la emancipación y la presencia de la mujer en todos los ámbitos de la sociedad.Escuchar audio
In this episode, we discuss the anti-aging effects of therapeutic plasma exchange (TPE) with Dr. Irina Conboy, a professor in the Department of Bioengineering at UC Berkeley. Her current research focuses on unraveling the key signal transduction pathways that regulate adult stem cell behavior – and understanding how these pathways change with age… From synthetic biology to CRISPR technologies, Dr. Conboy has been working in the fields of aging and genetic diseases for decades. Is aging a disease that can be solved? If so, what role does TPE play in it? If you're interested in the mysterious topic of human aging, this podcast is undoubtedly for you! Jump in to find out: What TPE is, and what it's used for. The benefits of “rebooting” blood signal proteins. What blood plasma is, and how it is produced in the human body. How TPE is linked to anti-aging. You can follow along with Dr. Conboy and her lab's work here. Episode also available on Apple Podcasts: http://apple.co/30PvU9C
Baby KJ Muldoon was born with a rare genetic condition that is often fatal, but doctors used custom CRISPR gene therapy to target the exact mutation in his DNA. His family shares their emotional journey in their first TV interview with CBS News. Singer Cassie Ventura faced intense cross-examination in Sean "Diddy" Combs' sex crimes trial, with defense attorneys asking her to read aloud past text messages. Jericka Duncan reports on the disturbing details.In this week's "Kindness 101," Steve Hartman and his children revisit the story of a teenage athlete who started giving back to his community after a small suggestion inspired a profound shift in his outlook on life.In honor of Mental Health Awareness Month, Amazon Books Editorial Director Sarah Gelman shares titles focused on self-care, emotional wellness and navigating complex relationships. To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
On Food Talk with Dani Nierenberg, Dani speaks with Matthew Dillon, Co-CEO of the Organic Trade Association. They discuss why the organic label continues to resonate with eaters, what the budget cuts and staffing reductions at the U.S. Department of Agriculture could mean for food producers, and why support for organic agriculture remains so important for communities today and in the future. Plus hear about the recent decision to approve CRISPR gene-edited pigs for human consumption in the U.S., a new project that will help Libyan producers farm in some of the driest conditions, and the food safety warnings that aren't reaching the public fast enough. While you're listening, subscribe, rate, and review the show; it would mean the world to us to have your feedback. You can listen to “Food Talk with Dani Nierenberg” wherever you consume your podcasts.
This Oncology PER®Spectives™ podcast explores the role of EZH2 in metastatic castration-resistant prostate cancer (mCRPC) progression and its synergy with androgen receptor inhibitors. In this podcast, experts Neeraj Agarwal, MD, FASCO; Himisha Beltran, MD; and Maha Hussain, MD, FACP, FASCO, discuss the management of mCRPC. Acknowledgment of Educational Grant Support This activity is supported by an educational grant from Pfizer Inc. Accreditation/Credit Designation Physicians' Education Resource®, LLC, is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Physicians' Education Resource®, LLC, designates this enduring material for a maximum of 1.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians' Education Resource®, LLC is approved by the California Board of Registered Nursing, Provider #16669, for 1.5 Contact Hours. Instructions on How to Receive Credit Listen to this podcast in its entirety. Go to gotoper.com/credit and enter code: 6947 Answer the evaluation questions. Request credit using the drop-down menu. You may immediately download your certificate. Today's faculty are: Neeraj Agarwal, MD, FASCO Professor of Medicine Senior Director for Clinical Research HCI Presidential Endowed Chair of Cancer Research Director, Center of Investigational Therapeutics Director, Genitourinary Oncology Program Huntsman Cancer Institute, University of Utah (NCI-CCC) Salt Lake City, UT Disclosures: Grant/Research Support (paid to institution): Arvinas, Astellas, AstraZeneca, Bayer, Bristol Myers Squibb, Calithera, Celldex, Clovis, Crispr, Eisai, Eli Lilly, EMD Serono, Exelixis, Genentech, Gilead, GlaxoSmithKline, Immunomedics, Janssen, Lava, Merck, Nektar, Neoleukin, Novartis, Oric, Pfizer, Roche, Sanofi, Seagen, Takeda, Tra-con Himisha Beltran, MD Associate Professor of Medicine Director of Translational Research Within Medical Oncology Harvard Medical School Lank Center for Genitourinary Oncology and the Division of Molecular and Cellular Oncology Dana Farber Cancer Institute Boston, MA Disclosures: Grant/Research Support: Circle Pharma, Daiichi Sankyo, Novartis; Adviser: Amgen, AstraZeneca, Daiichi Sankyo, Novartis Maha Hussain, MD, FACP, FASCO Genevieve E. Teuton Professor of Medicine Professor, Medicine (Hematology/Oncology) Deputy Director Robert H. Lurie Comprehensive Cancer Center Northwestern University Feinberg School of Medicine Chicago, IL Disclosures: Advisory Board: AstraZeneca, Bayer, Convergent Therapeutics, Honoraria: AstraZeneca, Bayer The staff of Physicians' Education Resource®, LLC, have no relevant financial relationships with ineligible companies. PER® mitigated all COI for faculty, staff, and planners prior to the start of this activity by using a multistep process. Off-Label Disclosure and Disclaimer This activity may or may not discuss investigational, unapproved, or off-label use of drugs. Learners are advised to consult prescribing information for any products discussed. The information provided in this accredited activity is for continuing education purposes only and is not meant to substitute for the independent clinical judgment of a health care professional relative to diagnostic, treatment, or management options for a specific patient's medical condition. The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of PER® or any company that provided commercial support for this activity. Release Date May 14, 2025 Expiration Date May 14, 2026
#3em1Agro, confira os destaques desta quarta-feira (14/05/25):➡️ Governo recua e reduz alíquota de novo imposto no agro. Saiba onde!➡️ Nascem os primeiros bezerros editados por CRISPR na América Latina. Saiba o que muda na pecuária. ➡️ China prevê menor importação de soja em 2025/26. Entenda a estratégia.
In this thrilling installment of Impact Theory, Tom Bilyeu sits down with Ben Lamm, visionary founder and CEO of Colossal Biosciences, a company on a mission to reverse extinction and rewrite the future of conservation and synthetic biology. Ben and Tom dive deep into the mind-bending world of de-extinction, synthetic gene editing, and how the CRISPR revolution is not only unlocking the secrets of life—but also actively engineering it. In Part 1, get ready for a rollercoaster of concepts as Ben explains the technical magic behind gene editing, DNA synthesis, and multiplex genome editing. From the birth of the woolly mouse to the debated revival of dire wolves, Ben reveals the breakthroughs, challenges, and wild stories behind reviving extinct species. You'll learn how Colossal is using advanced computational biology, AI, and hands-on bioengineering to not only bring animals back but also reshape the future of healthcare, genetics, and ethical decision-making. This is part sci-fi, part practical science, and 100% mind-blowing. SHOWNOTES 00:00 – Kicking Off: The Mysteries of Editing Life 00:14 – Emergence of the CRISPR Revolution 01:31 – What Is DNA Synthesis and Multiplex Editing? 03:47 – The Woolly Mouse: Engineering Traits Across Species 07:54 – Breaking Down the Process: IVF, Screening, and Sequencing 09:24 – Mapping Genotype to Phenotype and Its Challenges 12:10 – Targeting Gene Edits: From Theory to Application in Health and Conservation 17:09 – From Hair Organoids to Building Mammoth Traits in Mice 24:41 – The Quest for a Universal Egg and Overcoming Cellular Barriers 26:17 – Artificial Wombs: The Next Frontier in Conservation and Science 31:12 – Scaling Conservation and Bridging to Human Healthcare FOLLOW BEN LAMM Twitter/X: @federallamm LinkedIn: Ben Lamm CHECK OUT OUR SPONSORS ButcherBox: Ready to level up your meals? Go to https://ButcherBox.com/impact to get $20 off your first box and FREE bacon for life with the Bilyeu Box! Vital Proteins: Get 20% off by going to https://www.vitalproteins.com and entering promo code IMPACT at check out Shopify: Sign up for your one-dollar-per-month trial period at https://shopify.com/impact Netsuite: Download the CFO's Guide to AI and Machine Learning at https://NetSuite.com/THEORY iTrust Capital: Use code IMPACTGO when you sign up and fund your account to get a $100 bonus at https://www.itrustcapital.com/tombilyeu Mint Mobile: If you like your money, Mint Mobile is for you. Shop plans at https://mintmobile.com/impact. DISCLAIMER: Upfront payment of $45 for 3-month 5 gigabyte plan required (equivalent to $15/mo.). New customer offer for first 3 months only, then full-price plan options available. Taxes & fees extra. See MINT MOBILE for details. What's up, everybody? It's Tom Bilyeu here: If you want my help... STARTING a business: join me here at ZERO TO FOUNDER SCALING a business: see if you qualify here. Get my battle-tested strategies and insights delivered weekly to your inbox: sign up here. ********************************************************************** If you're serious about leveling up your life, I urge you to check out my new podcast, Tom Bilyeu's Mindset Playbook —a goldmine of my most impactful episodes on mindset, business, and health. Trust me, your future self will thank you. ********************************************************************** LISTEN TO IMPACT THEORY AD FREE + BONUS EPISODES on APPLE PODCASTS: apple.co/impacttheory ********************************************************************** FOLLOW TOM: Instagram: https://www.instagram.com/tombilyeu/ Tik Tok: https://www.tiktok.com/@tombilyeu?lang=en Twitter: https://twitter.com/tombilyeu YouTube: https://www.youtube.com/@TomBilyeu Learn more about your ad choices. Visit megaphone.fm/adchoices
How can writings from Daniel & John be “closed & sealed,” but then be revealed in the Last Days? By them being discovered! Pastor Gene Pensiero Find audio, video, and text of hundreds of other prophecy updates at: https://calvaryhanford.com/prophecy Read along with us at https://calvaryhanford.substack.com Follow us on YouTube at https://youtube.com/calvaryhanford — Welcome to Prophecy […]
In Episode 95 of Brave New World, Palaeontologist Peter Ward returns to explore life's evolutionary journey and examine compelling possibilities for its future direction. Useful Resources: 1. Peter Ward on Wikipedia and The University Of Washington. 2. Stephen Jay Gould. 3. Wonderful Life: The Burgess Shale and Nature Of History – Stephen Jay Gould. 4. Cambrian Explosion. 5. Burgess Shale. 6. Nick Lane. 7. Oxygen: The Molecule That Made The World – Nick Lane. 8. Life Ascending: The Ten Great Inventions of Evolution – Nick Lane. 9. David Catling on Wikipedia and the University Of Washington. 10. Eukaryote. 11. Lynn Margulis. 12. Carl Sagan. 13. Chemoreceptors. 14. My Octopus Teacher. 15. Pippa Ehrlich On The Mysteries of The Sea – Episode 77 Of Brave New World. 16. Methuselah Foundation and Methuselah Mice. 17. CRISPR. 18. Future Evolution – Peter Ward. 19. After Man: A Zoology Of The Future - Dougal Dixon. 20. Future Evolution with Alexis Rockman 21. Rare Earth: Why Complex Life is Uncommon in the Universe – Peter Ward and Donald Brownlee. 22. Seth Shostak on Extraterrestrial Life – Episode 85 of Brave New World. 23. Drake Equation. 24. Endangered Species Act, Clean Air Act. 25. Daniel J. Evans. 26. David Battisti 27. Edward O. Wilson 28. Biophilia – Edward O. Wilson Check out Vasant Dhar's newsletter on Substack. The subscription is free!
Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma and Biotech world.Novo Nordisk predicts a brighter future for Wegovy with the end of the semaglutide shortage, but analysts remain skeptical as Eli Lilly's Zepbound gains ground in sales. The new HHS vaccine requirement has raised questions about its true intentions, with leading vaccine physician Paul Offit criticizing the lack of clarity. Meanwhile, pharmaceutical imports from Ireland are on the rise, biotech stocks fell after Vinay Prasad was named to succeed Marks at CBER, and Lotte Biologics' ADC facility in Syracuse offers end-to-end services for antibody manufacturing. CRISPR's Casgevy is gaining traction with more gene therapy proof of concept expected in 2025, impacting M&A and IPOs in the biotech industry. Summit Pharmaceuticals is nearing the first global phase III data for Keytruda, set to lose exclusivity in 2028 and potentially face competition from biosimilars. A report suggests that low-price drug nations are benefiting from US innovation, undervaluing innovative medicines by 90%. VC financing in biopharma declined by 20% in Q1, but megarounds kept the median deal size high. M&A and IPOs faced challenges due to policy issues, leading to an increase in licensing deals. Novo vows to improve market access for Wegovy, while Trump orders FDA to ease US plant expansion and increase inspections of foreign facilities. BMS pledges a $40 billion investment in the US, Novartis makes M&A moves, and Lilly remains unfazed by CVS's decision to side with Novo in the obesity market battle. Some drugmakers are stockpiling products in the US amid Trump's trade war. NGM terminates half of its staff as its lead asset moves through a registrational study. Job opportunities in clinical quality assurance audit, RBQM central statistical monitoring, and field medical capabilities are available.
In his effort to onshore manufacturing, President Donald Trump issued an executive order on Monday afternoon ordering the FDA to ease permitting processes for new and expanded U.S. facilities. The announcement comes as more and more Big Pharma companies commit billions to expanding their U.S. footprints. Bristol Myers Squibb CEO Christopher Boerner announced this week that the company will pump $40 billion into its stateside operations over the next five years, even as the pharma executes a massive cost-cutting effort that involves shaving $3.5 billion from expenses by 2027 and cutting thousands of jobs, including another 516 in New Jersey, according to a May WARN notice. In other policy news, the Department of Health and Human Services on Wednesday said it will require all new vaccines to be tested in placebo-controlled trials to earn FDA approval but some vaccine experts have raised concerns about this approach. Meanwhile, turmoil still envelopes the FDA, with staff cuts and rehires continuing at a dizzying pace. On Monday, several states sued HHS, saying that the cuts offload critical functions and costs onto the states and impede public health efforts. As Q1 earnings season for Big Pharma begins to wind down, there are still headlines coming from the biotech sector. Vertex revealed last week that it is abandoning all of its adeno-associated virus vector work, while BioNTech on Monday announced that tariffs could get in the way of its ambitious plans for a closely watched PD-L1-VEGF therapy. Moderna, meanwhile, continues its fall from COVID grace, missing Q1 revenue expectations and announcing plans to reduce operating expenses by around $1.5 billion by 2027. In the weight loss space, Novo Nordisk announced on Friday that the FDA has accepted the application for a pill version of Wegovy, with a decision expected this fall. Novo has also struck partnerships with CVS and Hims & Hers pharmacies to market injectable Wegovy, drawing the attention of Eli Lilly CEO David Ricks. Also this week, check out BioSpace's deep dives into advances in base editing—a technology that's been touted as a “safer” CRISPR—and Summit Therapeutics' push to bring closely watched PD-1/VEGF immunotherapy ivonescimab to the U.S. market after its recent approval in China.
Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma and Biotech world.Two companies, Beam Therapeutics and Verve Therapeutics, have developed lead candidates using a safer alternative to conventional CRISPR called base editing. Clinical results have been promising. FDA insiders are calling on FDA Commissioner Marty Makary to fight against agency politicization. The Trump administration, including HHS Secretary Robert F. Kennedy Jr., is accused of distorting and denying scientific truths and potentially censoring information.FDA action alerts include expansion bids for drugs by GSK and Merck. A new AI-powered solution called Generative AIPTP helps life sciences firms streamline clinical workflows. The FDA is rehiring travel staff as lapses begin to show.RFK Jr. is driving a wedge into vaccine conversations. WHO may add obesity drugs for adults to the essential medicines list. Various companies like Merck, GSK, and Roche present key data at AACR 2025.HHS will require placebo-controlled trials for all new vaccines in a radical departure from past practices. Tariffs dominate Q1 earnings, AACR excites the cancer space, CEO pay gaps are discussed, and more news and events are highlighted.
Featuring Dave Beverley Sr (Jesus Freak Computer Geek), Pete Ohlinger (Days of Noah Podcast), & Dr. Alphonzo Monzo (DrMonzo.com)Join host Rod Smith on the Millennial Mustard Seed Podcast for a riveting exploration into how cutting-edge science and technology intersect with the spiritual realm. In this episode, our distinguished panel dives into the transformative worlds of CRISPR gene editing, Stargate AI, and nutraceuticals—and examines their spiritual and ethical implications.• CRISPR & Gene Editing: What are the potential spiritual ramifications of altering our genetic blueprint? Our panel discusses whether these advancements might be seen as aligning with or challenging divine design.• Electro Genetic Stimulation - Can Bio energetic intelligence serve as a medium to control Parasites and synthetic vampiric life forces?How might these breakthroughs interact with spiritual forces? Explore the possibility that modern science and technology are playing an unforeseen role in the cosmic battle between light and darkness.• Panel Perspectives: Hear from Dave Beverley Sr, Pete Ohlinger, and Dr. Alphonzo Monzo as they blend scientific insight with a biblical lens, challenging conventional narratives and inspiring deeper faith in Christ.• Plant a seed in time of need: https://creators.spotify.com/pod/show/rodney-jay/subscribe• Email Rod Smith:mmseed@proton.me Partner with Our Ministry: Consider supporting and partnering with us as we spread the Gospel through innovative media.• Buy a Copy of My New Book! https://a.co/d/3Gf5sqK• Venmo:@Rodney-Smith-368• PayPal:@creative775• Cash App:$Rodsworth77
https://youtu.be/oMFbMFvDJ50 Podcast audio: In this talk, Dr. Amesh Adalja details innovative new developments in science that will enhance the lives of individuals. Topics include transplantation of pig hearts and kidneys into humans, cell-based therapies for cancer, genetically modified mosquitoes, new vaccines and vaccine technologies, AI-discovered antibiotics, CRISPR therapeutics, and more. Recorded live on June 15 in Anaheim, CA as part of OCON 2024.
We don't hear about it very often, but there are geographical changes happening right now in Israel that are in accordance with unfulfilled prophecies. Pastor Gene Pensiero Find audio, video, and text of hundreds of other prophecy updates at: https://calvaryhanford.com/prophecy Read along with us at https://calvaryhanford.substack.com Follow us on YouTube at https://youtube.com/calvaryhanford — Welcome to […]
在之前的节目中,我们分享过悉达多•穆克吉医生的《癌症传》和《基因传》,最近他的第三部作品《细胞传》的中文版也在中国上市。作为一线的医疗工作者,穆克吉医生书写的不止是医学的发展史,也是人类在探索疾病的过程中对生命的关怀与致敬。我们本期节目邀请到穆克吉医生生命三部曲的中文译者马向涛医生,作为外科医生和译者,他对疾病的治疗和生命的价值也有着自己独特的思考。【本期嘉宾】马向涛,北京大学外科学博士,研究员/副主任医师。译有《生活之道》《细胞传》《癌症传》《基因传》《认识身体》《肿瘤临床试验》等专著【时间轴】01:30 从医生到译者:翻译与行医一样,都是不完美的艺术08:10 花八年翻译「癌症传」,跟每一句话死磕11:00 封面背后的隐喻:螃蟹符号背后的千年抗癌史14:20 曾尝试写一本书,但远比想象中困难16:30 《癌症传》中的争议:我们要以怎样的态度面对医学进步的代价?18:10 疾病的治疗不只是科学问题,也是伦理问题21:30 科技狂飙的背面:CRISPR baby 事件再反思26:30 AI 能够代替人来翻译吗?29:30 基因和细胞治疗的未来是什么?【相关单集】《癌症传》:我们可以治愈癌症吗?Yesn't! | E27《基因传》:我们在认识自己还是想成为上帝?|E39
The one and only Dr. Bryan Ardis is here—and today, we're challenging one of the most controversial narratives in health: nicotine. No, this isn't about lighting up a cigarette or vaping with fruity flavors. We're talking about nicotine as a nutrient—its natural presence in foods like tomatoes, peppers, and eggplants, and its surprising potential to boost immune function, sharpen cognition, and even help prevent chronic disease. From Parkinson's to insulin resistance and autoimmunity, Dr. Ardis explains how small, intentional doses of nicotine may support healing—and why pharmaceutical interests have kept this truth buried. But we don't stop there. Towards the end, we go even deeper, unpacking the use of venoms in medicine, what viruses really are, and what you need to know about the future of pharmaceuticals and genetic manipulation. In this episode, you'll learn: • Why nicotine is naturally found in plants—not just tobacco • How dietary nicotine may support brain health, inflammation, and the immune system • The truth about nicotine addiction, safe dosage, and FDA narratives • How venoms are used in food, cosmetics, and medicine • The deeper connection between toxins, modern medicine, and genetic engineering This conversation is bold, evidence-packed, and guaranteed to make you think differently. If this episode challenged what you've been told—follow, subscribe, and leave a review.
Joining us on Well Said is licensed social worker and motivational speaker, Michael Kalberer and director at the Inherited Retinal Disorders Service at The Massachusetts Eye and Ear hospital and Assistant Professor of Ophthalmology at Harvard Medical School, Dr. Jason I. Comander. They will be talking about CRISPR gene editing, a technology that can contribute […]
CRISPR therapies, Boeing, and Reconnecting with Alondra Nelson
It is a Nobel-winning idea with untold promise in health care, agriculture and more. We examine what must change in order to capture those benefits. Asia's love affair with gold has long been chalked up to cultural motives; our correspondent finds far more going on (10.45). And for all the draw of New Zealand's verdant chill, lots of natives want out (17:58). Get a world of insights by subscribing to Economist Podcasts+. For more information about how to access Economist Podcasts+, please visit our FAQs page or watch our video explaining how to link your account. Hosted on Acast. See acast.com/privacy for more information.
It is a Nobel-winning idea with untold promise in health care, agriculture and more. We examine what must change in order to capture those benefits. Asia's love affair with gold has long been chalked up to cultural motives; our correspondent finds far more going on (10.45). And for all the draw of New Zealand's verdant chill, lots of natives want out (17:58). Get a world of insights by subscribing to Economist Podcasts+. For more information about how to access Economist Podcasts+, please visit our FAQs page or watch our video explaining how to link your account.
Sam and Dylan are back to break down Chinese spies, CRISPR gene editing, Drake's pass, Lena Dunham, CIA Airlines, shadow wars and more. Dates at SamTripoli.com Check out Dylan's instagram - https://www.instagram.com/dylanpetewrenn/ PATREON IS HERE! Subscribe at Patreon.com/AkaDeepWaters for uncensored episodes and one EXTRA EPISODE every week! Check out Deep Waters Instagram: https://www.instagram.com/akadeepwaters/ Check out Bad Tv podcast: https://bit.ly/3RYuTG0 Thanks to our sponsors! Use Promo Code CSC at the Draft Kings Sports Book CBDX.com Promo Code: DEEP for 20% OFF
April 10, 2025Have you had your dose of The Daily MoJo today? Download The Daily MoJo App! "Ep 041025: I Don't Really Like Them - The Daily MoJo"Brian opens with congratulations to senators and discusses the implications of Trump's tariff decisions, which have led to market fluctuations. The conversation highlights the challenges retailers face with rising costs and supply chain issues. It also touches on cultural practices related to toilet paper, political commentary, and the role of CRISPR technology in health. The session concludes with a debate on political violence and the Tesla Cybertruck's design.*Brad's Note: WTH is Brian?Phil Bell's Morning Update The art of the [tariff] deal. HEREJeff Fisher - Host of Chewing The Fat Podcast - Dumped us for Pat Gray this morning, can you believe it?! Jeff Fisher LinktreeBrandon Morse - Redstate Author & host of The Brandon Morse YouTube channel- has strong feelings for Jasmine Crockett. Brandon's LinktreeOur affiliate partners:Pantell Less Lethal Protection - an official dealer of Byrna Technologies - has your alternative to deadly force. It's the Byrna Launcher, and it's legal in all 50 states! Check your state's laws for any special restrictions that may exist. Find the Byrna Launcher that's perfect for you: Ross's Cell: 908.642.2636ProtectMyMoJo.comPromo Code: DailyMojoRomika Designs is an awesome American small business that specializes in creating laser-engraved gifts and awards for you, your family, and your employees. Want something special for someone special? Find exactly what you want at MoJoLaserPros.com There have been a lot of imitators, but there's only OG – American Pride Roasters Coffee. It was first and remains the best roaster of fine coffee beans from around the world. You like coffee? You'll love American Pride – from the heart of the heartland – Des Moines, Iowa. AmericanPrideRoasters.com Find great deals on American-made products at MoJoMyPillow.com. Mike Lindell – a true patriot in our eyes – puts his money where his mouth (and products) is/are. Find tremendous deals at MoJoMyPillow.com – Promo Code: MoJo50 Life gets messy – sometimes really messy. Be ready for the next mess with survival food and tools from My Patriot Supply. A 25 year shelf life and fantastic variety are just the beginning of the long list of reasons to get your emergency rations at PrepareWithMoJo50.comStay ConnectedWATCH The Daily Mojo LIVE 7-9a CT: www.TheDailyMojo.com (RECOMMEDED)Watch:Rumble: HEREFacebook: HEREFreedomsquare: HEREYouTube: HEREListen:LISTEN: HEREBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-daily-mojo-with-brad-staggs--3085897/support
In what is likely to be one of the major science stories of the year, Texas-based Colossal Biosciences has brought the dire wolf—or at least something very close to this ice age canine—back from extinction, with the help of genetic engineering. The remarkable achievement has been met with awe, praise, and also controversy, as experts debate the exact nature of the "dire wolves" the company has created, as well as the implications of the breakthrough and the creation of what some might call life not as we know it. This week on The Micah Hanks Program, we take a look at the remarkable news, as well as the current state of genetic science, and whether it could one day be used on humans. Finally, we also turn our attention toward popular science fiction and bizarre theories regarding alien life, and whether questions about human contact with non-human forms of intelligence might involve advanced genetic engineering. Have you had a UFO/UAP sighting? Please consider reporting your sighting to the UAP Sightings Reporting System, a public resource for information about sightings of aerial phenomena. The story doesn't end here... become an X Subscriber and get access to even more weekly content and monthly specials. Want to advertise/sponsor The Micah Hanks Program? We have partnered with the AdvertiseCast to handle our advertising/sponsorship requests. If you would like to advertise with The Micah Hanks Program, all you have to do is click the link below to get started: AdvertiseCast: Advertise with The Micah Hanks Program Show Notes Below are links to stories and other content featured in this episode: NEWS: US stocks whipsaw on tariff uncertainty, social media rumors Perseverance Rover Witnesses One Martian Dust Devil Eating Another Groundbreaking Discovery at “Unusual” Ancient Burial Site Rewrites Neolithic History Camera set up to catch Loch Ness Monster unearthed COLOSSAL: The Dire Wolf, an Extinct Canine that Roamed Prehistoric America, Has Been Resurrected RISE OF ‘HOMO SUPERIOR': Could we make a superhuman? NEW FRONTIERS: Could CRISPR be used to Cre ate New Species? BECOME AN X SUBSCRIBER AND GET EVEN MORE GREAT PODCASTS AND MONTHLY SPECIALS FROM MICAH HANKS. Sign up today and get access to the entire back catalog of The Micah Hanks Program, as well as “classic” episodes, weekly “additional editions” of the subscriber-only X Podcast, the monthly Enigmas specials, and much more. Like us on Facebook Follow @MicahHanks on X. Keep up with Micah and his work at micahhanks.com.