Podcasts about CRISPR

In this episode of 10X Growth Strategies, host Arthi Vijayaraghavan sits down with Lakshmi Nair — drug development scientist and genetic engineering researcher — to unpack the science, promise, and responsibility behind CRISPR and gene editing. Drawing from her journey across academia and biomedical research, Lakshmi explains how CRISPR transformed genetic engineering from slow, uncertain experimentation into precise DNA editing — and why that leap could reshape medicine, cancer treatment, and hereditary disease forever. From transgenic models and drug development to the realities of scientific failure and perseverance, the conversation reveals what modern biomedical innovation truly looks like behind the scenes. The episode explores the ethical frontier of gene editing — germline modification, designer traits, disability vs identity, and who gets to decide what should be “fixed” in humans. The discussion also connects CRISPR with AI-driven research, data-intensive clinical trials, and the global scientific ecosystem that turns basic research into life-saving therapies. From biohacking and scientific curiosity to regulation, responsibility, and the future of humanity, this is a thoughtful, deeply grounded conversation on what it means to hold the power to rewrite life itself. A fascinating listen for technologists, policymakers, investors, and anyone curious about where biology, AI, and human evolution intersect. ⸻ 00:00 – Introduction & Lakshmi's Background 02:00 – Why CRISPR Changed Genetic Engineering 06:00 – Scientific Journeys, Curiosity & Upbringing 12:00 – CRISPR Explained for Non-Biologists 18:30 – Medical Applications: Cancer & Genetic Disease 23:30 – Scientific Collaboration & Peer Review 26:30 – Biohacking & Democratizing Biology 30:00 – Gene Editing Ethics & Germline Debate 36:00 – Identity, Disability & Human Choice 40:00 – From Lab Research to Drug Development 45:00 – AI in Clinical Trials & Biomedical Data 50:00 – Future of Gene Editing & Responsibility 54:00 – Closing Reflections

This interview of Alex Newman, the founder and CEO of Liberty Sentinel Media, by Ginger and Peter Breggin focuses on the newly released “million of Epstein pages” by the Trump Administration. Newman has been studying Epstein for many years, especially in light of his multiple globalist connections, including his support from America's Deep State bureaucracy. Alex Newman analyses newly released pages from the Epstein files concerning Epstein's work to further globalist ambitions for transhumanistic projects at Harvard and other universities, including using recently developed CRISPR technology to produce genetically modified human beings. We discuss the relationship between the evil psychology underpinning globalism, imperialism, and transhumanism, and how it poses a threat to all of Western civilization, including its goal to annihilate Christianity. The three of us discuss not only these mind-bending issues but also our own psychological and emotional blocks to even thinking about or writing about them, especially the existence of such horrendously evil intentions motivating many of the most powerful and influential people on Earth.

Pairwise: https://www.pairwise.com/FoA 412: 'Biological' Is Not A Category (it's the future of agriculture)I'm excited to share today's episode with you. I've wanted to get Tom Adams back on the show ever since I had the chance to interview him at World Agritech a couple of years ago. That interview was included on episode 412 of this podcast titled “Biological is not a Category”. The work Pairwise is doing is mind boggling to me. Using CRISPR and the latest in gene editing tools, they have built a platform to enable plant breeders to make very precise changes to the genome of a plant to give farmers and consumers more of what they want. Now this is different from genetic modification or GMOs because they are not inserting foreign genes into the plant. In fact, they are doing the exact same thing that plant breeders have done for over a century, they are just able to do it in an extremely precise way. On another podcast that I host, Agriscience Explained, Corteva's Reza Rasoulpour explained natural breeding as wanting to change one word in a book by just combining all of the pages of two different books and hoping that word changes. Versus gene editing just going in and changing that one word in the book. I thought that was a good comparison. So Tom and his team are bringing this technology to agriculture by working with seed companies and other partners in a variety of use cases, many of which we'll discuss today. A little background on Tom: Dr. Tom Adams co-founded Pairwise and serves as Chief Executive Officer. Tom has over 25 years of leadership experience heading up biotechnology for global companies, serving most recently as Vice President of Global Biotechnology at Monsanto where he led the team developing a broad range of innovative products. Tom wanted to realize the possibilities of CRISPR and gene editing in plants, and co-founded Pairwise to realize this potential in a mission-based environment. Formerly a faculty member at Texas A&M University, Tom holds a PhD in microbiology and plant science from Michigan State University and a BS in botany and plant pathology from Oregon State University. Tom and I talk about Pairwise's continued work in this area, some of the cool developments that are under way, some of their strategic decisions like going the partnership route rather than being the seed company themselves, a little bit more about how the technology works, how this changes the game and who captures the value.

Crispr's ability to cut genetic code like scissors has just started to turn into medicines. Now, gene editing pioneer Jennifer Doudna wants to build an entire ecosystem to bring these treatments mainstream. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode, he and Niklas explore how genome sequencing, DNA synthesis, and CRISPR are turning life into an engineering platform. From coding proteins and viruses to writing entire genomes, Andrew explains how biotech is moving from reading DNA to actively programming it.They discuss N-of-1 personalized therapies, biosecurity in an age of cheap DNA synthesis, and why open science could accelerate biotech innovation. The conversation also touches on cloning, embryo editing, and the long-term future of human enhancement.Topics include:· DNA as digital code · Genome writing and synthetic cells · CRISPR and programmable biology · Personalized genetic medicine · Biosecurity and engineered viruses · Open biotech vs. proprietary models · Cloning and human genome designA conversation for builders, founders, and technologists thinking about biology as the next software layer. This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.infinitacitytimes.com

Today, we're joined by Professor Matthew Wood, a leading figure in neuroscience and RNA-based therapeutics. He is Professor of Neuroscience at the University of Oxford, Deputy Head of the Medical Sciences Division, and Director of both the MDUK Oxford Neuromuscular Centre and the Oxford-Harrington Rare Disease Centre, a groundbreaking partnership between the University of Oxford and Harrington Discovery Institute dedicated to accelerating therapies for rare genetic diseases affecting millions worldwide.In today's episode we discuss his vision for making antisense oligonucleotides (or ASOs) and gene editing more modular, more scalable, and faster by collaborating with regulators, scientists, and patient groups to bring hope to those with rare neuromuscular and genetic conditions.With rare disease day coming up just next week, I hope you enjoy the insights that Professor Wood shares on the future of the fight against rare disease.01:23 – Meet Matthew Wood07:26 – The Oxford-Harrington Rare Disease Centre10:33 – Collaborations, philanthropy, and industry partnerships13:55 – Key challenges in rare disease therapy development20:00 – Modular and scalable platforms for ASOs28:08 – Scaling gene editing like CRISPR for rare diseases32:38 – Role of AI and computational tools in acceleration37:28 – Future breakthroughs in rare disease treatments44:07 – Advice for new researchers in the fieldInterested in being a sponsor of an episode of our podcast? Discover how you can get involved here! Stay updated by subscribing to our newsletterTo dive deeper into the topic: Prader Willi syndrome: five much-anticipated therapies poised for approval First-ever approval for Barth Syndrome treatment: what does this mean for ultra-rare disease therapeutics? When rare diseases are not so rare after all: A closer look at where and why this happens

Patrick Bet-David and Rhonda Patrick explore AI's explosive rise, gene therapy, CRISPR, stem cell reprogramming, and longevity breakthroughs. They debate designer genetics, IQ enhancement, organ regeneration, and whether the future belongs to superhumans or authentic human imperfection.

Welcome to the Inverted Orthodoxy Podcast! We're Blake, Kyle, and Doug the pastors from Living Springs, here to take you on a weekly adventure through the twists and turns of faith. Got questions? We've got answers, and sometimes more questions! Join us as we explore, celebrate, and embrace the beautiful complexities of belief. This week we tackled a lot of questions: 1. AERPastors… I know ya'll really wanted snow for the youth tobogganing that's happening on Wednesday… but I think one of you prayed WAY too hard!!! Haha 2. In our recent series on 1 Corinthians, in v24-25 of chapter 15, it refers to Jesus handing over the kingdom to God and father.  How do you read and interpret this. We refer to the kingdom of God, but does this verse refer to the Kingdo. Of Jesus, as he hasn't handed it over to the father yet? I would appreciate your thoughts on this.3. If you could gain clarity about one verse or a couple of verses which would you choose and why?4. What kind of resurrection did Lazuras experience? Did he have the same kind of body Jesus had after his resurrection?5. In school I'm learning about determinism. Compatibilism and free will. Which one do you believe according to logic, experience and scripture? Quick definitions: DeterminismThe view that every event—including human thoughts and actions—is caused by prior events and conditions, leaving no real possibility for things to happen otherwise. Free WillThe ability to make genuine choices that are not completely determined by external forces or past events. CompatibilismThe belief that determinism and free will can both be true—human choices can be determined and still count as free if they reflect a person's desires, intentions, and reasoning.6. What are your thoughts on CRISPR and genetic editing? Is it similar to other technology and tools where there is both good and bad ways to use it, or does the bad too greatly outweigh the good in this case? And furthermore is it too close to playing God, changing how our bodies are designed at a genetic level?7. I like many of the worship songs we sing in church, some are so individualistic in our pursuit of faith and Jesus. Do you see more value in some songs if we were to change the ‘I' to ‘we' and bring them into a more corporate singing/ worship expression.  My other minor question would be we talk about it as a time of signing at church and not a time of worship; would love to know the heart and rationale behind this.8. After Jesus' resurrection, we are told that we no longer have anything to fear, but how can we not fear for our unsaved loved ones?9. What is you favourite bible/Christian joke? What does a pirate say after praying? Arrr-menDo you have a question you've been wanting answered? Head on over to our website www.invertedorthodoxy.com to submit a question. You can find us on Wednesdays on Youtube, or wherever you subscribe to podcasts. To learn more about our church, you can visit www.livingspringsairdrie.com

We love to hear from our listeners. Send us a message. On this week's episode of the Business of Biotech, Jared Bauer, Cofounder and CEO at Seek Labs, talks about his adventures in company turnarounds, and setting up Seek Labs to improve patient diagnoses and to discover and develop new treatments for infectious diseases. Jared explains the technology convergence that was needed to build Seek Labs' AI diagnostic and CRISPR-based therapeutics platform, an African Swine Fever proof-of-concept study that reduced viremia in pigs, mapping pathogens for rapid target design, and engaging with the FDA and global regulatory agencies.       Access this and hundreds of episodes of the Business of Biotech videocast under the Business of Biotech tab at lifescienceleader.com. Subscribe to our monthly Business of Biotech newsletter. Get in touch with guest and topic suggestions: ben.comer@lifescienceleader.comFind Ben Comer on LinkedIn: https://www.linkedin.com/in/bencomer/

Cholesterin wurde lange Zeit auf gutes HDL- und schlechtes LDL-Cholesterin reduziert – dass diese Sicht zu kurz greift, belegt aktuelle Forschung. In dieser Episode spricht Priv.-Doz. Dr. med. habil. Katharina Lechner vom Helmholtz Zentrum München über einen Marker, der das kardiovaskuläre Risiko präziser abbilden kann als LDL-Cholesterin allein: Apolipoprotein B (ApoB). Wir besprechen, - warum eine Messung der Anzahl aller ApoB-Partikel das individuelle Herz-Kreislauf-Risiko genauer widerspiegelt als klassische Cholesterinwerte. - wieso genetisch bedingte Fettstoffwechselstörungen durch einen gesunden Lebensstil nicht ausreichend kontrollierbar sind. - wann eine medikamentöse Therapie sinnvoll ist – und welche modernen Behandlungsmöglichkeiten zur Verfügung stehen. - warum Lipoprotein(a) als eigenständiger Risikofaktor mindestens einmal im Leben gemessen werden sollte. - welche Rolle die Ernährung, regelmäßiges Krafttraining und Schlaf in der Prävention spielen. Katharina Lechner erklärt, wie moderne Medizin Risiken frühzeitig sichtbar machen kann, lange bevor Symptome auftreten. Die renommierte Kardiologin und Forscherin mit Schwerpunkt auf Lipidologie und personalisierter Prävention zeigt, wie patientenzentrierte, datenbasierte und lebensbegleitende Strategien unsere Gefäßgesundheit langfristig schützen können."Der ERCM Medizin Podcast" Social & Webseite:Instagram: https://www.instagram.com/ercm.podcast/ TikTok: https://www.tiktok.com/@ercm.podcast?lang=de-DE Webseite: http://www.erc-munich.com Kontakt: podcast@erc-munich.comPrivatdozentin Dr. med. Katharina Lechner:Helmholtz Zentrum München: https://www.helmholtz-munich.de ("https://www.helmholtz-munich.de")Über das ERCM:Im Europäischen Radiochirurgie Centrum München (ERCM) setzen wir seit über 20 Jahren auf präzise Tumortherapien: hochmoderne Radiochirurgie und innovative Medizintechnologien zur gezielten und schonenden Behandlung verschiedener Tumoren – gutartige Neubildungen ebenso wie schwere Krebserkrankungen. Jahr für Jahr schenken uns mehr als 1.000 Patientinnen und Patienten ihr Vertrauen auf dem Weg zu einer individuell abgestimmten Therapie. Unser Ziel: Personalisierte, präzise und vor allem patientenzentrierte Behandlungen, die auf eine effektive und nebenwirkungsarme Therapie bei guter Lebensqualität fokussieren.(00:00:00) Intro(00:00:50) ApoB: Der wichtigste Marker für Herz-Kreislauf-Risiko(00:07:24) Warum ApoB nicht im Standard-Labor ist(00:09:50) Normalwerte vs. Idealwerte: Der größte Blindspot(00:18:04) Deutschland im europäischen Vergleich: Letzter Platz(00:19:23) Genetische vs. erworbene Fettstoffwechselstörungen(00:54:48) Lipoprotein(a): Der vergessene Risikofaktor(00:32:25) Cardio-CT: Plaques sichtbar machen(00:42:07) Statine: Wirkung, Nebenwirkungen und richtige Dosierung(00:46:00) Neue Therapien: Von Antikörpern bis CRISPR(01:11:22) Ketogene Ernährung: Lean Mass Hyper-Responder(01:01:21) Lebensstil: Die 95-Prozent-Regel für Gesundheit(01:09:01) CORA Digital Fit: Personalisiertes Coaching(01:21:14) Take-Home-Message: Die drei wichtigsten Werte#Cholesterin #ApoB #LipoproteinA #Herzinfarkt #Schlaganfall #Prävention #Statine #Lipidstoffwechsel #CardiovaskuläreGesundheit #Fettstoffwechsel #HerzKreislauf #ERCMPodcast #KatharinaLechner #PCSK9 #Kardiologie

I'm going to introduce us to a map of North America. It is an old map, but it is contemporary as well. It's the Technate Map of America. Pastor Gene Pensiero Find audio, video, and text of hundreds of other prophecy updates at: https://calvaryhanford.com/prophecy Read along with us at https://calvaryhanford.substack.com Follow us on YouTube at […]

Young people are bio-hacking and gene-hacking in the absence of adult supervision. An emulated personality become an event host. Slice and scan brain digitizers are found. People want to use these to upload to the cloud but there are some grave problems involved. Grace gets a message on her computer from someone or something. Hacking her computer should be impossible. It could be a talented hacker or a super AI left over after the fall of civilization. Lenny is having girl troubles.Mag tech flooring that levitates shoes slightly above the ground to reduce friction and allow controlled sliding movement.  Lifter bots that are headless robotic machines with grippers used for heavy lifting, transport, and forced entry.  Air-gesture control systems that let users operate machines and interfaces through mid-air hand movements.  Gene-hacking technologies that allow people to alter physical traits such as skin reflectivity, hair color, muscle mass, height, and eye color.  Engineered ogra plants that function as a food source, structural material, and biological air filtration system.  Bio-hacked skin modifications that create metallic, glowing, fluorescent, or patterned skin effects.  Printed clothing with animated images that dynamically change visuals on fabric surfaces.  Contraptions for brain slicing and scanning that destroy the biological brain while attempting to digitize its structure.  Brain scanners designed to capture neural structure for attempted uploading into digital systems.  Uploading systems intended to transfer scanned brains into cloud-based environments.  The cloud infrastructure used to host emulated personalities and digital systems after widespread network collapse.  Emulated personalities (EPs) that are AI systems trained on massive recordings of a person to mimic behavior without scanning their brain.  AR glasses that overlay holographic information, interfaces, and visual enhancements onto the real world.  Holographic eye displays embedded in glasses that mirror the wearer's eye expressions.  Encrypted streaming pendants and bracelets used as personal recording and life-capture devices.  Production automation systems that manufacture tools, machines, and devices with minimal human labor.  Advanced fabrication equipment capable of high-end manufacturing but limited by scarcity of raw materials.  Medicine printers that can fabricate biological materials and advanced hardware like protein-based CPUs.  Protein computer CPUs that use biological substrates instead of traditional silicon for computation.  Material simulators that computationally discover novel materials and predict their properties.  Machine Evolver software that simulates machines under real-world physics and evolves designs through virtual iteration.  Knotts math, a radically new mathematical framework that functions as both math and machine language.  Knotts programming language derived from knotts math and used to build operating systems and software.  Custom Linux operating systems rewritten around knotts math principles.  SSH-based remote access systems used to control computers and robots across networks.  Assist, a pervasive AI helper that manages security, media generation, device control, and logistics.  Design expert emulated personalities used to contribute specialist knowledge to engineering projects.  AI systems that convert legacy software into knotts-based programming languages.  Virtual machine crossbreeding networks that allow simulated designs to recombine traits and evolve faster.  E-paper tablets used for low-power note-taking, sketching, and code analysis.  YattaZed remote programming software used to control robots at the administrator level.  YattaSwarm GUIs that manage coordinated groups of robots as a collective system.  Blind-relay networking techniques that disguise communication paths to evade surveillance.  Door operating systems that act as networked nodes capable of running code and relaying messages.  Artificial superintelligence (ASI) that surveils human activity and suppresses certain technologies like knotts.  Digitized hume brains created by scanning and emulating real human brains rather than approximating them with AI.  Neural emulators that provide a computational environment capable of running a full digitized brain.  Virtual reality worlds repurposed as living environments for emulated minds.  Insta-movie generation systems that create personalized films on demand using AI.  Event AI controllers that manage live performances, streaming, lighting, and audience interaction.  Holographic projection systems that display life-sized interactive personalities like Guru Frisky.  Fiber optic hair strands woven into hairstyles to produce glowing light effects.  Exoskeleton suits that augment movement and interface with VR systems.  Mag plate floors used with exoskeletons to allow free-floating VR locomotion.  Advanced VR rigs that replace fixed robotic arms with wearable movement systems.  AI-generated optical illusion art that responds to prolonged visual focus.  3D printing systems capable of producing statues, clothing, tools, and components from various materials.  Mist crystal composite printing materials used as a lightweight alternative to legacy plastics.  Biotic makeup that integrates into the skin rather than sitting on the surface.  CRISPR-based gene editing equipment used by individuals for self-modification.  Viral vector printers that dispense customized gene-editing serums.  Scan-measured clothing printers that adjust garment dimensions as bodies change.  Pain-dampening genetic modifications that reduce or block physical pain responses.  Metabolic enhancement gene edits that increase energy efficiency and muscle performance.  Straw-sized bots woven into hair that act as decorative, animated micro-robots.  Fire axes used as low-tech tools to breach secured doors when automation fails.Many of the characters in this project appear in future episodes.Using storytelling to place you in a time period, this series takes you, year by year, into the future. From 2040 to 2195. If you like emerging tech, eco-tech, futurism, perma-culture, apocalyptic survival scenarios, and disruptive science, sit back and enjoy short stories that showcase my research into how the future may play out. The companion site is https://in20xx.com These are works of fiction. Characters and groups are made-up and influenced by current events but not reporting facts about people or groups in the real world. This project is speculative fiction. These episodes are not about revealing what will be, but they are to excited the listener's wonder about what may come to pass.Copyright © Cy Porter 2026. All rights reserved.

Audra Lynn Fasano joins Tony to share her firsthand experience of being drawn into Jeffrey Epstein's network, beginning with her time at the Playboy Mansion and escalating into blackmail, intelligence ties, and operating as a middleman between elites. She recounts how threats against her family forced her deeper into the web, and why she believes Epstein was only one cog in a much larger machine. The conversation moves beyond trafficking into increasingly dark territory, ritual abuse, bloodline targeting, CRISPR technology, transhumanism, and what Audra sees as a modern Babylonian control system still unfolding today. She connects ancient sites, Nephilim lore, and elite funding networks to current technological initiatives, arguing that the end goal reaches far beyond exploitation. Through it all, Audra emphasizes spiritual warfare, deliverance, and returning to Christ as the only true protection in an escalating battle. This is a sobering discussion about power, deception, and why discernment may be more critical now than ever.Please pray for Tony's wife, Lindsay, as she battles breast cancer. Your prayers make a difference!If you're able, consider helping the Merkel family with medical expenses by donating to Lindsay's GoFundMe: https://gofund.me/b8f76890Become a member for ad-free listening, extra shows, and exclusive access to our social media app: theconfessionalspodcast.com/joinThe Confessionals Social Network App:Apple Store: https://apple.co/3UxhPrhGoogle Play: https://bit.ly/43mk8kZThe Counter Series Available NOW:The Counter (YouTube): WATCH HEREThe Counter (Full Episode): WATCH HEREThe Big Picture Prophecy Conference: prophecyconference26.comTony's Recommended Reads: slingshotlibrary.comIf you want to learn about Jesus and what it means to be saved: Click HereBigfoot: The Journey To Belief: Stream HereThe Meadow Project: Stream HereMerkel Media Apparel: merkmerch.comMy New YouTube ChannelMerkel IRL: @merkelIRLMy First Sermon: Unseen BattlesSPONSORSSIMPLISAFE TODAY: simplisafe.com/confessionalsGHOSTBED: GhostBed.com/tonyCONNECT WITH USWebsite: www.theconfessionalspodcast.comEmail: contact@theconfessionalspodcast.comAudra Lynn FasanoFacebook | Unseen Targets | Unseen Chains | Unseen SpiritsEpstein Justice - Click HereMAILING ADDRESS:Merkel Media257 N. Calderwood St., #301Alcoa, TN 37701SOCIAL MEDIASubscribe to our YouTube: https://bit.ly/2TlREaIReddit: https://www.reddit.com/r/theconfessionals/Discord: https://discord.gg/KDn4D2uw7hShow Instagram: theconfessionalspodcastTony's Instagram: tonymerkelofficialFacebook: www.facebook.com/TheConfessionalsPodcasTwitter: @TConfessionalsTony's Twitter: @tony_merkelProduced by: @jack_theproducerOUTRO MUSICJoel Thomas - "Rose In A Cage"YouTube | Apple Music | Spotify

 Ryan Clarke, Co-Founder, CEO, and CTO of Syntax Bio, is focused on solving manufacturing challenges in producing stem cell-derived therapies, specifically the process of stem cell differentiation. The Cellgorithm platform was designed to make differentiation an engineering problem by using a modified form of CRISPR to turn genes on and off in a specific, controlled sequence, reducing processing time from months to days and resulting in cost savings. One goal is to use AI and machine learning to build models capable of predicting optimal gene regulation sequences accelerating the discovery of new differentiation protocols and treatments for degenerative diseases. Ryan explains, "The key problem that we are focused on applies to stem cell-derived cell therapies. And so, just for a little bit of context setting, we use induced pluripotent stem cells or IPS cells. And about 20 years ago, when these were first derived, everybody was very excited because this is the platform where you could then have an infinite supply of stem cells to then make any tissue-specific cell type at will, theoretically. Fast forward 20 years, and there are finally some cell therapies in phase three clinical trials, but none are approved yet. And that just tells you that the development cycle for this modality is actually slower than the other modalities, like biologics or small molecules. And the problem is manufacturing in particular, or how do you convert the stem cell into the target tissue cell type for the process of stem cell differentiation? And so we are solely focused on making stem cell differentiation an engineering problem rather than a kind of dark art."   "We have a program for type one diabetes that is making pancreatic beta cells from IPS cells. And we have also done some work in the musculoskeletal system. So these other cell types we focus on are more demonstrations of the platform technology, but we are interested in possibly co-developing those with other pharmaceutical partners, and that's the musculoskeletal cells of the hematopoietic system. And we've done some work on retinal cells as well, but we endeavor to make many other cell types. And our goal is to partner with the therapeutic experts in the area to develop these." #SyntaxBio #CellTherapy #CRISPR #StemCells #Biotech #RegenerativeMedicine #Diabetes #Manufacturing #Innovation #GeneTherapy #LifeSciences #Bioengineering #SyntheticBiology #CellProgramming syntax-bio.com Listen to the podcast here

 Ryan Clarke, Co-Founder, CEO, and CTO of Syntax Bio, is focused on solving manufacturing challenges in producing stem cell-derived therapies, specifically the process of stem cell differentiation. The Cellgorithm platform was designed to make differentiation an engineering problem by using a modified form of CRISPR to turn genes on and off in a specific, controlled sequence, reducing processing time from months to days and resulting in cost savings. One goal is to use AI and machine learning to build models capable of predicting optimal gene regulation sequences accelerating the discovery of new differentiation protocols and treatments for degenerative diseases. Ryan explains, "The key problem that we are focused on applies to stem cell-derived cell therapies. And so, just for a little bit of context setting, we use induced pluripotent stem cells or IPS cells. And about 20 years ago, when these were first derived, everybody was very excited because this is the platform where you could then have an infinite supply of stem cells to then make any tissue-specific cell type at will, theoretically. Fast forward 20 years, and there are finally some cell therapies in phase three clinical trials, but none are approved yet. And that just tells you that the development cycle for this modality is actually slower than the other modalities, like biologics or small molecules. And the problem is manufacturing in particular, or how do you convert the stem cell into the target tissue cell type for the process of stem cell differentiation? And so we are solely focused on making stem cell differentiation an engineering problem rather than a kind of dark art."   "We have a program for type one diabetes that is making pancreatic beta cells from IPS cells. And we have also done some work in the musculoskeletal system. So these other cell types we focus on are more demonstrations of the platform technology, but we are interested in possibly co-developing those with other pharmaceutical partners, and that's the musculoskeletal cells of the hematopoietic system. And we've done some work on retinal cells as well, but we endeavor to make many other cell types. And our goal is to partner with the therapeutic experts in the area to develop these." #SyntaxBio #CellTherapy #CRISPR #StemCells #Biotech #RegenerativeMedicine #Diabetes #Manufacturing #Innovation #GeneTherapy #LifeSciences #Bioengineering #SyntheticBiology #CellProgramming syntax-bio.com Download the transcript here

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Meet Billy Carson in Atlanta Mar 1st https://www.unlockdivinitycodes.com/Billy Carson will mentor you free for days. https://4bkacademy.com

CEREMONIAL SCI OP - 02.09.2026 - #914 BestPodcastintheMetaverse.com Canary Cry News Talk #914 - 02.09.2026 - Recorded Live to 1s and 0s Deconstructing World Events from a Biblical Worldview Declaring Jesus as Lord amidst the Fifth Generation War! CageRattlerCoffee.com SD/TC email Ike for a discount https://CanaryCry.Support   Send address and shirt size updates to canarycrysupplydrop@gmail.com Join the Canary Cry Roundtable This Episode was Produced By:   Executive Producers Michael B*** Sir LX Protocol Baron of the Berrean Protocol***   Producers of TREASURE (CanaryCry.Support) Cage Rattler Coffee   Producers of TIME Timestampers: Jade Bouncerson, Morgan E Clankoniphius Links: JAM   SUPPLY DROP Calendar and Goldback bonus to new sign ups   OLYMPICS DEVIL 2:48 Ring "Search party"  Clip: Olympics Pentagram Clip: Spiral imagery at opening ceremony (X) Clip: Israeli's boo'd at opening ceremony, walking through Stargate (X) Clip: Israel boo'd? (X)  Israeli Bobsled team Robbed (Fox) → Clip: Milan protests are intense → Clip: more protest footage AP gives no reason for riots at Olympics (AP) → DHS post, sent ICE agents to Italy for Olympics, quotes Variety (X)  Suspected saboteurs hit Italian rail network near Bologna, police say (CBC)   EPSTEIN 1:33:28 Note: France former culture minister resigns over Epstein (AP) Cclip: Ro Khana on the destruction of the royal family (cnn)  'Evil': Conservatives ERUPT on Steve Bannon Over Epstein Revelations (MediaIte) Epic Games denies rumors about presence of Jeffrey Epstein alive and playing Fortnite (MSN) Epstein heavily involved in "Micro-transactions" in video games Epstein WoW account and money laundering (IBT)   -Epstein Reportedly Ordered Multiple 55-Gallon Sulfuric Acid in 2018: 'Likely Used to Dissolve Bodies of Children' (IBT) → 330-Gallon Sulfuric Acid Purchase in 2018 Sparks Speculation (Criminal Watch) → He ordered 6x55 gallons which = 330 (X)   SCIENCE IS TRUTH 2:26:33 1-CRISPR removes chromosome to cure Down syndrome (Time of India) → Innovative Approach Developed for Removing Extra Chromosome 21 in Cells from Individuals with Down Syndrome Using CRISPR-Cas9 Genome Editing Technology (MIE) 2-First human trials of locally-developed HIV jab begin in South Africa (Yahoo/Telegraph) 3-Mexican Researchers Breakthrough That Could Lead to Complete Elimination of HPV (I24)   CANCER 2:30:55 4-Spanish scientists cure pancreatic cancer in mice in medical breakthrough (Fox) 5-Korean Scientists Reversed Colon Cancer Cells to Normal State (Open Gate Media) 6-Precision conversion of colorectal cancer lung metastases (NIH) 7-Russia unveils first test batches of cancer vaccine (RT) 8-Scientists discover 'levitating' time crystals that you can hold in your hand (Phys.org) 9-New type of magnetism discovered in 2D materials (Phys.org) Clip: Uncles Tremble as Man Invents Vaccine Delivered by Beer (Futurism)   GATES OF THE GODS/SPACE 2:39:29 *Scientists Say Heck, Just Nuke a Killer Asteroid Heading for Earth (Futurism)   EXECUTIVE PRODUCERS 2:47:57 TALENT/TIME 3:00:25 END 3:12:08

Biotechnology is advancing faster than ever before, and the stakes have never been higher. In this episode, Dr. Christopher Cummings, lead for the Center for Health Engineering with the U.S. Army Corps of Engineers, breaks down why the convergence of biotech and artificial intelligence is creating both unprecedented opportunities and existential risks. From gene-edited foods that could revolutionize agriculture to AI-designed viruses that could destabilize nations, Dr. Cummings explores the delicate balance between innovation and oversight. He reveals why traditional regulatory frameworks are struggling to keep pace and how "information hazards" are forcing scientists to rethink transparency itself. We dive into the ethical minefield of black-boxed AI systems, designing biological solutions, the growing trust gap between lab and consumer, and what it means when AI can "de-skill" biotechnology to the point where expertise is no longer required to create dangerous organisms.  Topics covered: CRISPR and gene editing, AI convergence, biosafety and bioweapons, public trust in GMOs, generational attitudes toward biotech, risk communication, international cooperation, and the future of governance in an accelerating technological landscape.

HEADLINE: Charles Lieber and the CRISPR Threat. GUEST: Brandon Weichert. SUMMARY: Weichert highlights Charles Lieber's conviction and He Jiankui's unethical gene experiments, illustrating how China exploits dual-use biotechnology to advance military goals and defeat Western rivals.PEKING 1904

Contributor: Alec Coston, MD Educational Pearls: Disclaimer: this has nothing to do with the ER but is too cool to not talk about. Condition: Carbamoyl phosphate synthetase 1 (CPS1) deficiency Rare inborn error of metabolism Inability to properly break down ammonia Leads to severe hyperammonemia and hepatic encephalopathy Natural history: Without treatment, typically fatal within the first few weeks of life Even with current standard treatments, life expectancy is often limited to ~5–6 years Breakthrough treatment: A team of researchers at the Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania developed the CRISPR-based targeted gene therapy for this patient. First-of-its-kind precision approach tailored to the patient's specific mutation Key components of the therapy: Whole-genome sequencing to identify the exact CPS1 mutation Creation of a custom base-editing enzyme designed to correct that specific mutation Design of a guide RNA to direct the base editor to the precise genomic location Delivery method: Lipid nanoparticles used to deliver the gene-editing machinery Nanoparticles can be targeted to specific tissues Why the liver works well: CPS1 is primarily expressed in hepatocytes The liver is relatively easy to target with lipid nanoparticles Hepatocytes divide frequently, allowing edited genes to be passed on as cells replicate Long-term impact: Once edited, cells continue producing functional CPS1 enzyme Potential for durable, possibly lifelong correction from a single treatment References https://www.nih.gov/news-events/news-releases/infant-rare-incurable-disease-first-successfully-receive-personalized-gene-therapy-treatment Choi Y, Oh A, Lee Y, Kim GH, Choi JH, Yoo HW, Lee BH. Unfavorable clinical outcomes in patients with carbamoyl phosphate synthetase 1 deficiency. Clin Chim Acta. 2022 Feb 1;526:55-61. doi: 10.1016/j.cca.2021.11.029. Epub 2021 Dec 29. PMID: 34973183. Bharti N, Modi U, Bhatia D, Solanki R. Engineering delivery platforms for CRISPR-Cas and their applications in healthcare, agriculture and beyond. Nanoscale Adv. 2026 Jan 5. doi: 10.1039/d5na00535c. Epub ahead of print. PMID: 41640466; PMCID: PMC12865601. Summarized and edited by Jeffrey Olson MS4 Donate: https://emergencymedicalminute.org/donate/ Join our mailing list: http://eepurl.com/c9ouHf

Welcome back for some Unfiltered Conspiracy! Mormons always show up this is true… however this one was surprising even to me! The occult, while meaning hidden also has a dark definition as well.What goes on behind the lives of the top elites? What happened at the ranch owned by Epstein?DNA manipulation, CRISPR and Howard Hughes all make an appearance. All of this is confusing and maybe it's meant to be..However remember there is always two truths and a lie! Let's dive in and see what we flush out with Ben from Tree of Liberty Podcast.Give him a follow at his link belowGuest Links: https://treeoflibertysociety.com/X: https://x.com/treeoflibertys/status/1999181800716001608?s=46Unfiltered Rise Podcast Links Website: https://unfilteredrisepodcast.com/Patreon: https://patreon.com/UnfilteredRise?IG: https://www.instagram.com/unfilteredrise_podcast?igsh=MWE4NnQ2Y2Zxa3pnNw%3D%3D&utm_source=qrYouTube: https://youtube.com/@unfilteredrisepodcast?si=GP1pu_CC8kkvNlFyX: https://x.com/unfilteredrise/status/1772012349551153303?s=46TikTok: https://www.tiktok.com/Merch: https://heidi-luv-shop.fourthwall.com/Donations: https://www.buymeacoffee.com/unfilteredEPlease subscribe if you haven't all ready and consider supporting my work! There are several books I need and am working towards.A review and subscribing is just as precious if you cannot! Ty to you all! God Bless and all glory to him each and every day! Please know my podcast and its information presented are for entertainment or informational purposes. I do not threaten or wish any harm to any nation,creed, color, religion etc …. #Utah #Mormonism #Epstein #Mormon #LDS #history #occultmormonism #Epsteinfiles #Mormonblood #Unfilteredconspiracy

On this episode of Purple Political Breakdown, host Radell Lewis dives deep into the newly released Epstein files, breaking down the 3.5 million pages of DOJ documents and what they reveal about Donald Trump, Bill Clinton, Elon Musk, Bill Gates, Prince Andrew, and other high-profile names. Who's being protected by the redactions, and why are victims being exposed while powerful men stay hidden? Then Radell tackles the gas prices myth head-on with a full research segment on how gas prices actually work from crude oil and OPEC production decisions to refinery closures and global supply and demand and why no U.S. president, Republican or Democrat, controls what you pay at the pump. Plus: Operation Metro Surge and the ICE crackdown in Minnesota, the FBI's raid on Fulton County's election office with Tulsi Gabbard on speakerphone with Trump, the massive Democratic special election upset in Texas, Trump's cratering approval ratings, how Twitter's algorithm is skewing political reality, the measles outbreak under RFK, and the 2026 midterms outlook. The show wraps with ten good news stories the media won't tell you about, from CRISPR gene therapy breakthroughs to malaria vaccine success in Ghana. Political solutions without political bias. New episodes every Sunday at 8 AM EST. Keywords: Epstein files, Epstein documents release, Trump Epstein, Clinton Epstein, Elon Musk Epstein, gas prices explained, who controls gas prices, OPEC, crude oil prices, ICE Minnesota, Operation Metro Surge, Fulton County FBI raid, 2026 midterms, Trump approval rating, Twitter algorithm bias, election integrity, tariffs, political podcast, nonpartisan politics, Purple Political Breakdown, Radell Lewis, Alive Podcast NetworkStandard Resource Links & RecommendationsThe following organizations and platforms represent valuable resources for balanced political discourse and democratic participation: PODCAST NETWORKALIVE Podcast Network - Check out the ALIVE Network where you can catch a lot of great podcasts like my own, led by amazing Black voices. Link: https://alivepodcastnetwork.com/ CONVERSATION PLATFORMSHeadOn - A platform for contentious yet productive conversations. It's a place for hosted and unguided conversations where you can grow a following and enhance your conversations with AI features. Link: https://app.headon.ai/Living Room Conversations - Building bridges through meaningful dialogue across political divides. Link: https://livingroomconversations.org/ UNITY MOVEMENTSUs United - A movement for unity that challenges Americans to step out of their bubbles and connect across differences. Take the Unity Pledge, join monthly "30 For US" conversation calls, wear purple (the color of unity), and participate in National Unity Day every second Saturday in December. Their programs include the Sheriff Unity Network and Unity Seats at sports events, proving that shared values are stronger than our differences. Link: https://www.us-united.org/ BALANCED NEWS & INFORMATIONOtherWeb - An AI-based platform that filters news without paywalls, clickbait, or junk, helping you access diverse, unbiased content. Link: https://otherweb.com/ VOTING REFORM & DEMOCRACYEqual Vote Coalition & STAR Voting - Advocating for voting methods that ensure every vote counts equally, eliminating wasted votes and strategic voting. Link: https://www.equal.vote/starFuture is Now Coalition (FiNC) - A grassroots movement working to restore democracy through transparency, accountability, and innovative technology while empowering citizens and transforming American political discourse. Link: https://futureis.org/ POLITICAL ENGAGEMENTIndependent Center - Resources for independent political thinking and civic engagement. Link: https://www.independentcenter.org/ GET DAILY NEWSText 844-406-INFO (844-406-4636) with code "purple" to receive quick, unbiased, factual news delivered to your phone every morning via Informed (https://informed.now) ALL LINKShttps://linktr.ee/purplepoliticalbreakdownThe Purple Political Breakdown is committed to fostering productive political dialogue that transcends partisan divides. We believe in the power of conversation, balanced information, and democratic participation to build a stronger society. Our mission: "Political solutions without political bias."Subscribe, rate, and share if you believe in purple politics - where we find common ground in the middle! Also if you want to be apart of the community and the conversation make sure to Join the Discord: https://discord.gg/ptPAsZtHC9

Episode 344 Elon Musk has announced he wants to merge SpaceX with another of his companies, xAI, and launch one million satellites into space. One reason - according to Musk - is to eventually harness the entire power of the sun, a sci-fi sounding idea that would make us a Kardashev Type II civilisation. But he also wants the satellites to help power AI and move data centres off Earth. Is his goal realistic… and what would be the consequences? Parents desperate to get their children to sleep are resorting to melatonin gummies - and it's proving very effective. Melatonin is a sleep hormone which is only available on prescription in many countries. So some parents are importing them from America - where they can be bought over-the-counter. The trouble is the long-term side effects are not really known - and cases of melatonin overdose in children are on the rise. Despite global agreement to cut the "overall risk" from pesticides by at least half by 2030 - new data shows we're not even close. Countries made this commitment at a UN biodiversity meeting in 2022, but so far it's been almost impossible to measure success. Thanks to a researcher in Germany, we now have a way to track our progress - and it's not looking good. Could an increase in organic farming be the solution, or CRISPR gene editing? Hosted by Rowan Hooper and Penny Sarchet, with guests Jonathan O'Callaghan, Alice Klein and Michael Le Page. To read more about these stories, visit https://www.newscientist.com/ Learn more about your ad choices. Visit megaphone.fm/adchoices

Wow what do cabbage babies, bloodlines, Crispr, and History especially of the orphan trains have in common?It may be more that you think! This wild research of mine is not new... this has been a question for me since I started my podcast almost 4 years ago.Knowing about Mormons, Utah and Genetics I went down the research road trying to find some answers.Especially now I am even more interested seeing the many strange pieces of the Epstein files, and of course as I always say some Mormons were there!I can't make it up thats for sure... So buckle up for a wild ride on this one and trigger warning for some sensitive photos. A big Thank You to Greyhorn Pagans for sharing the show and Please follow all of his work at the links below! Greyhorn Pagans https://www.greyhornpagans.com/https://open.spotify.com/show/03NlRDGZgczxwPaLh3ZX4j?si=iDt7X83ZRNWMlvk2328vhgUnfiltered RIse Podcast LinksWebsite: https://unfilteredrisepodcast.com/Patreon: https://patreon.com/UnfilteredRise?X: https://x.com/unfilteredrise/status/1772012349551153303?s=46IG: https://www.instagram.com/unfilteredrise_podcast?igsh=MWE4NnQ2Y2Zxa3pnNw%3D%3D&utm_source=qrYouTube: https://youtube.com/@unfilteredrisepodcast?si=IMlOVdcKU6oj4N8sTikTok: https://www.tiktok.com/@unfilteredrisepodcast?_t=8rjVXGsH2AY&_r=1Merch: https://heidi-luv-shop.fourthwall.com/Donations: buymeacoffee.com/unfilteredEPlease know my podcast and its information presented are for entertainment or informational purposes. I do not threaten or wish any harm to any nation,creed, color, religion etc …. God Bless

Juanjo de la Iglesia nos habla en 'Las Claves de La Brújula' sobre esta revolucionaria herramienta de modificación genética y sus implicaciones para la humanidad.

OPERATION NEPHILIM BUZZ - 02.04.2026 - #913 BestPodcastintheMetaverse.com Canary Cry News Talk #913 - 02.04.2026 - Recorded Live to 1s and 0s Deconstructing World Events from a Biblical Worldview Declaring Jesus as Lord amidst the Fifth Generation War! CageRattlerCoffee.com SD/TC email Ike for discount https://CanaryCry.Support   Send address and shirt size updates to canarycrysupplydrop@gmail.com Join the Canary Cry Roundtable This Episode was Produced By:   Executive Producers Sir Jamey Not the Lanister*** Sir LX Protocol Baron of the Berrean Protocol***   Producers of TREASURE (CanaryCry.Support) Cage Rattler Coffee, Alex W, Mrs TinfoilHatMan, Veronica D, Sir Scott Knight of Truth, Sir Casey    Producers of TIME Timestampers: Jade Bouncerson, Morgan E Clankoniphius Links: JAM   5GW 9:46 V CIA is recruiting Data Lifecycle analysts (X)   NEPHILIM UPDATE 27:01 V Viking-era burial pit filled with decapitated and mutilated bodies including 'giant' with 'hole in his skull' is found on outskirts of British city (DailyMail) Candace Nephilim Episode   BIBLICAL 48:38 V Polymarket: Jesus will return in 2027, doubles (X)   PANDEMIC SPECIAL 53:11 V CLIP: More info on the labs B1 person is arrested after a suspected biolab is found at Las Vegas home (AP) CRISPR: Senate Republican on suspected biolab found in LV: 'Enormous problem' (The Hill)   SEWER SURVEILLANCE 1:10:51 V -The Secret Weapon in Canada's Sewers (Maclean's CA) → Smart sanitary hardware for health monitoring (Nature)   EPSTEIN 1:24:55 V Zohran MamDanis mother appears in the epstien docs (SNOPES) Mira Nair was Married to Mitch Epstien (wiki) Zohran Epstein side by side 1 Zohran Epstein Side by side 2 → Was Epstein Andrew Jackson?   EXECUTIVE PRODUCERS TALENT/TIME END

Alberto Ciccia, Professor of Genetics and Development at Columbia University, joins us to discuss how cells protect their genomes and how these pathways intersect with cancer and immunity. He explains how his lab uses CRISPR-based genome-editing tools to map the DNA damage response and uncover new therapeutic targets. We also talk about his recent Cell study showing how the DNA damage response factor SMARCAL1 shapes immune signaling and tumor immune evasion. Throughout the conversation, Professor Ciccia reflects on mentorship, scientific creativity, and how advances in DNA repair research could translate into better diagnostics and treatments for patients.Hosted by Sophia Deng.

We love to hear from our listeners. Send us a message.In episode 121 of Cell & Gene: The Podcast, Host Erin Harris talks to Scribe Therapeutics' CEO and Co-Founder Benjamin Oakes about building next‑generation CRISPR and epigenetic editing tools to move genetic medicine beyond rare disease into common cardiometabolic indications. Oakes shares Scribe's engineered CasX platform and epigenetic silencers, preclinical data from its various programs, and why exquisite specificity and low-dose LNP delivery are essential to treating patients safely. They also explore Scribe's partnerships with Sanofi and Lilly, the company's cardiometabolic-first strategy co-developed with Dr. Jennifer Doudna, and Oakes' conviction that genetic medicines can fundamentally reshape healthspan and the future of preventive cardiovascular care.Subscribe to the podcast!Apple | Spotify | YouTube Visit my website: Cell & Gene Connect with me on LinkedIn

Food costs exploding, so we borrow money to increase inflation?Crispr'd pork on the shelves in Canada, but don't worry it's not cloned!Silver is pulling the “if there's a plan, even if it's horrible, at least there's a plan” phaseNigel Farage made a deal and is now losing support,Extortion crime a federal emergency?#Cpd #lpc, #ppc, #ndp, #canadianpolitics, #humor, #funny, #republican, #maga, #mcga,Sign Up for the Full ShowLocals (daily video)Sample Showshttps://canadapoli2.locals.com/ Spotify https://podcasters.spotify.com/pod/show/canadapoli/subscribePrivate Full podcast audio https://canadapoli.com/feed/canadapoliblue/Buy subscriptions here (daily video and audio podcast):https://canadapoli.cm/canadapoli-subscriptions/Youtubehttps://www.youtube.com/c/CanadaPoli/videosMe on Telegramhttps://t.me/realCanadaPoliMe on Rumblehttps://rumble.com/user/CanadaPoli Me on Odysseyhttps://odysee.com/@CanadaPoli:f Me on Bitchutehttps://www.bitchute.com/channel/l55JBxrgT3Hf/ Podcast RSShttps://anchor.fm/s/e57706d8/podcast/rsshttps://LinkRoll.co Submit a link. Discuss the link. No censorship. (reddit clone without the censorship)

When it comes to “bad” cholesterol, most cardiologists say lower is better. But what's the best way to get that number down? Can diet and exercise alone do the job?Cardiologists Kiran Musunuru and Neha Pagidipati join Host Ira Flatow for a look at the latest in cholesterol-lowering treatments, including CRISPR technology that could turn off cholesterol-making genes for life. How does it work, and is it safe?Guests:Dr. Kiran Musunuru is the scientific director of the Center for Inherited Cardiovascular Disease at the Perelman School of Medicine at the University of Pennsylvania.Dr. Neha Pagidipati is the director of the Cardiometabolic Prevention Clinic at the Duke University School of Medicine in Durham, NC.Transcripts for each episode are available within 1-3 days at sciencefriday.com.  Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

Mary Shelley's Frankenstein continues to captivate audiences centuries after its publication, but not all adaptations emphasize the same ethical questions. Matthew and returning guest AK dive into both the original novel and Guillermo del Toro's recent film adaptation—not to catalog their differences, but to explore how each medium handles the story's core moral dilemmas and which approach proves more compelling.How Does the Film Emphasize “The Other” Differently?While both the book and film explore themes of parentage, responsibility, and scientific hubris, they emphasize different ethical questions. AK notes that the novel places stronger emphasis on the responsibilities of individuals in medicine and parenting, particularly through the lens of abandonment. The film, however, foregrounds questions about the grotesque other, the monstrous other, and how appearance shapes moral judgment. The visual decisions in del Toro's adaptation—juxtaposing the creature against beautiful backdrops that shift with emotional moments—underscore this emphasis.How Does the Shift from Abandonment to Abuse Change Victor's Responsibility?One of the most striking differences between the book and film lies in Victor Frankenstein's initial interaction with his creation. In Shelley's novel, Victor creates the monster, goes to bed, wakes up, and immediately flees—abandoning the creature with almost no interaction. Del Toro's film takes a dramatically different approach: Victor spends considerable time with the creature, engaging with it in ways impossible in the book. This changes the fundamental ethical question. Does Victor bear responsibility for abandonment and neglect, or for intentional, directed abuse? The film's choice to show an extended period of interaction—where Victor treats the creature as an object rather than a being—shifts the moral weight of his culpability.Why Does the Composite Body Matter More Now Than Ever?Victor's method of selecting “optimal” body parts from different corpses to create his creature resonates uncomfortably with contemporary debates about human enhancement and biotechnology. The discussion explores how Victor's approach—viewing the creature as an optimization project rather than a living being—connects to modern questions about CRISPR, genetic modification, and who decides what constitutes an “optimal” human body. These questions inevitably involve ableism and the commodification of bodies. The film's emphasis on Victor literally selecting bodies at prisons raises urgent parallels to current concerns: Who becomes test subjects for experimental procedures like Neuralink? Are they being viewed as humans or as subjects for experimentation?Other Topics Covered:Why the novel's nested narrative structure (stories within stories) creates a unique moral complexityHow both works explore humanity's relationship to nature, science, and the line between achievement and hubrisThe challenge of adapting works from different historical contexts when what counted as scientific hubris has radically changedThe concept of viewing people as player characters (with their own interiority) versus non-player characters (existing only to advance your plot)Why Frankenstein's relevance grows as biotechnology makes questions of life preservation more immediateThe conversation reveals how both Shelley's novel and del Toro's film use the Frankenstein story to explore timeless questions through different emphases—one focusing on neglect and parental failure, the other on abuse and the othering of those who don't meet conventional standards of beauty or normalcy. **************************************************************************This episode is a production of Superhero Ethics, a The Ethical Panda Podcast and part of the TruStory FM Entertainment Podcast Network. Check our our website to find out more about this and our sister podcast Star Wars Generations.We want to hear from you! You can keep up with our latest news, and send us feedback, questions, or comments via social media or email.Email: Matthew@TheEthicalPanda.comFacebook: TheEthicalPandaInstagram: TheEthicalPandaPodcastsTwitter: EthicalPanda77Or you can join jump into the Star Wars Generations and Superhero Ethics channels on the TruStory FM Discord.Want to get access to even more content while supporting the podcast? Become a member! For $5 a month, or $55 a year you get access to bonus episodes and bonus content at the end of most episodes. Sign up on the podcast's main page. You can even give membership as a gift!You can also support our podcasts through our sponsors:Purchase a lightsaber from Level Up Sabers run by friend of the podcast Neighborhood Master AlanUse Audible for audiobooks. Sign up for a one year membership or gift one through this link.Purchase any media discussed this week through our sponsored links.

Avancerad genteknik används för att ta fram grisar som står emot klassisk svinpest genom att slå ut proteiner som viruset är beroende av. Lyssna på alla avsnitt i Sveriges Radios app. Klassisk svinpest är en virussjukdom som historiskt lett till masslakt, hårda avspärrningar och stora ekonomiska förluster. Med avancerad genteknik tas nu steg mot djur som inte längre kan infekteras av viruset. Arbetet bygger på att slå ut ett protein som viruset är beroende av för att föröka sig i grisens celler. När proteinet inte längre bildas stoppas smittan innan sjukdomen bryter ut.Forskare i Storbritannien och Kina har oberoende av varandra tagit fram grisar som visat tydlig motståndskraft mot klassisk svinpest, och resultaten imponerar erfarna veterinärmedicinare. Tekniken bygger på gensaxen CRISPR, där en exakt genförändring görs utan att påverka djurens tillväxt, reproduktion eller köttkvalitet enligt de uppföljningar som hittills gjorts.Samtidigt är hotet från svinpest större än på länge. Den afrikanska varianten, svårare och mer komplex, har nått både svenska vildsvin och flera europeiska länder. Forskare bedömer att den också är svårare att komma åt med genredigering och kräver flera genförändringar innan resistenta djur är möjliga.Genredigeringens framsteg öppnar ändå för ett framtida jordbruk där sjukdomar som idag orsakar enorma kostnader kan begränsas direkt i djurens arvsmassa. Frågan är hur snabbt tekniken kan nå marknaden – och om den kan förändra hur avel, smittskydd och livsmedelsproduktion ser ut i grunden.Reporter: Gustaf Klaringustaf.klarin@sr.seProducent: Lars Broströmlars.brostrom@sr.se

Send us comments, suggestions and ideas here! In this week's episode we explore two very real technologies which are just now getting off the ground and promise to completely change not just how we think about life and death itself, but what it means to be human. In the free side of the show we discuss what happens when we turn our dead grandma into a digital avatar we can keep on our phone forever and how this technology will be used to sabotage phone scammers. In the second half of the show we discuss the reality of night-vision eyes, breathing under water, re-growing limbs and Neurolink implants. We really enjoyed working on this one, thank you and enjoy the show!Visit www.patreon.com/TheWholeRabbit to hear the extended show! In this week's episode we discuss:Necro Grandma Babysitter?!AI TwinThe Tibetan Book of the DeadBlack Mirror: “Be Right Back”EcclesiastesRidden By the LoaIn the extended show available at www.patreon.com/TheWholeRabbit we discuss:Night Vision EyesUnderwater Breathing InjectionsLimb Regrowth Customizable EmbroyosNeurolink This episode was written by Heka and Luke with his parts in Red, hers in Purple, Mari in Blue, Chillz in light blue and Tim in black with moral support. Where to find The Whole Rabbit:Spotify: https://open.spotify.com/show/0AnJZhmPzaby04afmEWOAVInstagram: https://www.instagram.com/the_whole_rabbitTwitter: https://twitter.com/1WholeRabbitOrder Stickers: https://www.stickermule.com/thewholerabbitOther Merchandise: https://thewholerabbit.myspreadshop.com/Music By Spirit Travel Plaza:https://open.spotify.com/artist/30dW3WB1sYofnow7y3V0YoSources:2wai - Talking to your dead grandma:https://www.2wai.ai/2wai | Preserve Your LegacyOther Necromancy Apps:HereAfter AI: Where Memories Live ForeverThe Gift of a Lifetime: StoryFile LifeProfluent:https://www.profluent.bio/modality/opencrisprEditing human genome?https://en.wikipedia.org/wiki/He_Jiankui_affairSupport the show

We love to hear from our listeners. Send us a message.Welcome to episode 120 of Cell & Gene: The Podcast. Host Erin Harris is joined by Rachel Haurwitz, CEO of Caribou Biosciences, to discuss the company's progress in developing CRISPR-edited, off-the-shelf CAR-T therapies for hematologic malignancies. Their conversation centers on Vispacell, Caribou's allogeneic CD19 CAR-T for second-line large B-cell lymphoma. Haurwitz explains how Caribou has systematically optimized its allogeneic platform using clinical and translational data. They also cover pivotal Phase 3 trial planning, regulatory considerations, and what to expect next from Caribou's broader pipeline, including its BCMA-targeted program in multiple myeloma.Subscribe to the podcast!Apple | Spotify | YouTube Visit my website: Cell & Gene Connect with me on LinkedIn

Thanks for spending some time with us. We really appreciate all our listeners and hope that these studies through God’s Word have encouraged and inspired you to walk with Him more than ever before. If you’re looking for another study – check out one of our other podcasts. We’ve got dozens going through a variety […]

Episodio 596 con Francesca e Luca ai microfoni per una scorpacciata di notizie scientifiche dal defunto 2025. Iniziamo con gennaio 2025, quando è stato eseguito il secondo trapianto di un rene geneticamente modificato negli Stati Uniti.Ad aprile la Colossal Biosciences ha riportato in vita tre esemplari di enocione (o lupo terribile), un canide vissuto durante il Pleistocene. Per farlo, ha sequenziato il suo genoma da un dente di enocione di 13.000 anni fa e da un cranio di enocione di 72.000 anni fa, apportato 20 modifiche al DNA di lupo grigio per creare alcuni tratti fisici dell'enocione. A maggio è uscito sul New England Journal of Medicine probabilmente uno studio sul (https://doi.org/10.1056/NEJMoa2504747) primo trattamento personalizzato di editing genetico CRISPR eseguito su un bimbo di neanche un anno affetto da una patologia genetica molto rara. Il bimbo si chiama K.J. Muldoon ed è affetto dal deficit di CPS1, dove CPS sta per carbamoil-fosfato sintetasi 1, un enzima che trasforma l'ammoniaca in carbamoil-fosfato.Nell'esterna di oggi, Leonardo intervista Stefano Della Torre, ricercatore INFN che ci parla di come usando delle GPU (delle schede grafiche) siano riusciti a ridurre moltissimo il tempo necessario per risolvere i modelli che descrivono il comportamento dei raggi cosmici. Dopo una barza terribile, ritorniamo in studio. A giugno 2025 sono usciti due studi (https://doi.org/10.1126/science.adu9677 e https://doi.org/10.1016/j.cell.2025.05.040) in cui si analizzava un cranio quasi completo, risalente al 146000 anni fa, trovato in Cina nord-orientale e soprannominato cranio dell'“Uomo Drago”. (https://pmc.ncbi.nlm.nih.gov/articles/PMC8454562/).Un altro bel risultato per quanto riguarda le malattie genetiche l'ha ottenuto Sarah Tabrizi che, a settembre 2025, ha dichiarato il successo della sua gene-targeting therapy che potrebbe rallentare la progressione dalla malattia di Huntington (https://uniqure.gcs-web.com/news-releases/news-release-details/uniqure-announces-positive-topline-results-pivotal-phase-iii).Ad ottobre, invece, il giornale Psychiatric News ha pubblicato un report in cui veniva segnalata una nuova psicosi, chiamata “Psicosi indotta da IA” (https://doi.org/10.1176/appi.pn.2025.10.10.5). Si tratta di un nuovo disturbo neurologico per cui le persone iniziano a scambiare una chatbot per un essere cosciente, sviluppando allucinazioni, deliri e una vera e propria confusione della realtà.Da novembre 2025 il Canada non è più considerato un Paese libero dal morbillo. Molto probabilmente seguiranno a ruota gli Stati Uniti, per i quali il numero di casi è in largo aumento, con circa 2000 casi confermati in 43 paesi nel solo 2025. Purtroppo questa tendenza ad eludere l'obbligo vaccinale è in aumento, specialmente dopo il Covid-19 e le dichiarazioni di alcuni consulenti sanitari del governo americano di evitare la vaccinazione infantile contro l'epatite B. Tornando alla notizia del morbillo, ricordiamo che il vaccino contro morbillo, parotite e rosolia è estremamente efficace e protegge dal morbillo per tutta la vita, quindi mi raccomando: VACCINATEVI!Concludiamo l'episodio con due belle notizie leggere.Nello specifico di larve di mosconi che confondono le termiti con la loro culo-faccia (https://doi.org/10.1016/j.cub.2025.01.007), esponendo un posteriore mimetico che le confonde tra le termiti per "scroccare" vitto e alloggio.Se non lo sapevate, gli axolotl – che sono delle salamandre con caratteristiche neoteniche, ovvero è una specie che conserva caratteristiche morfologiche e fisiologiche tipiche dei giovani per tutta la vita, e con straordinarie capacità rigenerative – sono una specie a rischio di estinzione. Fortunatamente, però, alcuni ricercatori dell'Università Nazionale Autonoma del Messico sono riusciti ad introdurre axolotl allevati in cattività nel loro habitat naturale, i quali sono sopravvissuti, il che consentirebbe di ripopolare la popolazione selvatica (https://doi.org/10.1371/journal.pone.0314257).Diventa un supporter di questo podcast: https://www.spreaker.com/podcast/scientificast-la-scienza-come-non-l-hai-mai-sentita--1762253/support.

Good morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world. Today, we delve into a series of transformative updates reshaping drug development and patient care across the globe.Starting with a major collaboration between Roche and Medilink Therapeutics that has captured industry attention. Roche is making a strategic move by committing $570 million to partner on an antibody-drug conjugate, or ADC, targeting the B7-H3 immune checkpoint protein. This partnership underscores a broader industry trend focusing on immuno-oncology. ADCs have become pivotal due to their ability to deliver cytotoxic agents precisely to tumor cells, reducing systemic exposure and minimizing side effects. This precision not only enhances efficacy but also improves patient experience, marking a significant stride in cancer treatment modalities.In another strategic alliance, Pfizer has entered into a $50 million deal with Madrigal Pharmaceuticals for a DGAT2 inhibitor. Madrigal plans to pair this with its liver disease treatment, Rezdiffra, aiming to amplify therapeutic outcomes in liver conditions. This highlights an increasingly popular approach in medicine: polypharmacy and combination therapies. By tackling diseases from multiple angles, these therapies promise more comprehensive management of complex conditions, reflecting a shift towards more personalized and effective treatment strategies.Turning our attention to the startup landscape, "Baby KJ" Scientist has launched a new personalized CRISPR therapy company with $16 million in initial funding from Menlo Ventures. This venture signals growing interest in CRISPR technology for crafting bespoke genetic therapies. The potential for CRISPR lies in its ability to edit genomes precisely, opening possibilities for treating genetic disorders at their root cause and tailoring interventions to individual patients' genetic profiles.On the financial front, Aktis Oncology's successful IPO stands out, raising an impressive $318 million through an upsized offering. This achievement not only illustrates investor confidence in biotech but also suggests a more favorable atmosphere for upcoming biotech ventures seeking public funding. A robust financial ecosystem is crucial for fostering innovation and bringing cutting-edge therapies from the lab bench to the bedside.In another exciting development, Airnexis Therapeutics has secured $200 million to advance its COPD treatment asset in collaboration with a Chinese pharmaceutical firm. The total deal could reach up to $955 million in what's known as biobucks—a term used for milestone payments in biotech partnerships. This collaboration exemplifies the globalization of biotech partnerships, emphasizing the strategic importance of tapping into diverse markets for drug development and commercialization.Meanwhile, Ollin Biosciences is making waves with promising results from its bispecific antibody trial. The antibody showed superior efficacy in treating diabetic macular edema compared to Genentech's Vabysmo. This success potentially sets a new benchmark for retinal disease therapies and highlights the rapid evolution of bispecific antibodies. These agents can engage multiple targets simultaneously, offering enhanced therapeutic potential across various conditions.Leadership dynamics are also influencing the sector. Charles Fuchs has transitioned from his role as Roche's Global Head of Oncology and Hematology Product Development to Tubulis. Such moves suggest potential shifts in strategic focus for both companies involved, reflecting broader trends in leadership realignments within the industry. Additionally, Illumina's appointment of Eric Green as Chief Medical Officer showcases another instance of experienced leaders taking pivotal roles within companies at the forefront of genomic research. Such appointments underscore the imSupport the show

Investigative researcher Chris Crutchfield joins Faust in-studio to probe the Charlie Kirk investigation narrative: Candace Owens vs. Erica Kirk, ties to the military-industrial complex, and how everything connects to mass mind control in episode 233 of the Far Out with Faust podcast.In this conversation, Faust and Chris examine the Charlie Kirk investigation and the competing narratives that formed around it, including Candace Owens' scrutiny and Erica Kirk's public role. From there, the discussion widens into a deeper examination of psychological warfare, biological and nervous-system–level control, and narrative management, using the Kirk case as one example of how power, perception, and compliance are shaped in real time through both media and physical influence.In this episode:

Broadcast from KSQD, Santa Cruz on 1-01-2025: An emailer asks about omega-3 supplementation for memory at age 72. Dr. Dawn advises checking that fish oil capsules contain adequate DHA—at least 1,000 mg—since many omega-3 products have low DHA levels. She notes Medicare covers the same testing at standard labs as proprietary labs like OmegaQuant that charge patients directly. Beyond omega-3s, she emphasizes glucose control (hemoglobin A1c below 5.6) since the enzyme that breaks down insulin also clears beta-amyloid, and weight training to raise brain-derived neurotrophic factor (BDNF), which promotes new synapse formation essential for memory. Dr. Dawn reviews Popular Science's top 2025 health innovation: eye drops from Lens Therapeutics containing aceclidine that correct age-related farsightedness for 10 hours. The drops shrink the pupil to increase depth of field, improving near vision by three or more lines on eye charts within 30 minutes without affecting distance vision. Side effects include eye irritation, dimmed night vision, and headache. She describes Duke University's breakthrough allowing heart transplants from circulatory death donors using an on-table reanimation technique. This could expand the pediatric donor pool by 20%—critical since up to 20% of children die waiting for transplants. Dr. Dawn celebrates CAR-T immunotherapy for multiple myeloma, which saved her husband's life. Of 97 heavily pretreated patients, 38% achieved complete remission still present at five years, with over 50% total survival. The therapy removes T-cells, uses CRISPR to add receptors targeting cancer cell antigens, then reinfuses the modified cells. She highlights a UC Davis study showing remote blood pressure monitoring with home technology, education, and coaching dropped patients' average blood pressure from 150/80 to 125/74 in months—low-tech with high impact. Dr. Dawn explains the Nano Knife for prostate cancer, which uses localized electrical pulses delivered through thin wires to destroy tumors while sparing surrounding nerves. This minimally invasive approach could reduce erectile dysfunction and incontinence common with traditional surgery. She describes Gilead's Sunlenca, a twice-yearly injection for HIV prevention that's 99% effective. At $14,000 per injection in the US, proceeds help fund access in resource-limited countries where it can be distributed like a vaccination. Dr. Dawn discusses Journavx (suzetrigine), a new non-opioid pain medication working on sodium channels to block pain signals before reaching the brain. At $30 for 50 pills on GoodRx, it offers an alternative for surgical pain in patients with addiction history or genetic vulnerability to opioid dependence. She details the landmark case of Baby KJ, the first person to receive personalized CRISPR gene therapy. Born with a CPS1 enzyme deficiency causing toxic ammonia buildup, KJ was too small for liver transplant. Scientists identified his specific mutation and used CRISPR base editing delivered via lipid nanoparticles to correct a single DNA letter—changing an A to G—in his liver cells which restored enough function to be discharged home. Dr. Dawn reports surprising findings that COVID mRNA vaccines amplify cancer immunotherapy. Lung cancer patients who received COVID vaccination within 100 days of checkpoint inhibitor treatment had 56% three-year survival versus 31% for unvaccinated patients. The mechanism is unknown but may involve mRNA generally alerting the immune system. She revisits research showing Zostavax shingles vaccination reduced dementia risk by 20% over seven years. A natural experiment in Wales—where an age cutoff created comparable vaccinated and unvaccinated groups—provided strong evidence that preventing herpes zoster inflammation protects brain health. Dr. Dawn concludes with Huntington's disease breakthrough: microRNA therapy delivered by virus directly into the brain slowed disease progression by 75% over three years. The microRNA binds to Huntington protein mRNA, preventing ribosome translation and toxic protein production. Some patients returned to work; others expected to need wheelchairs are still walking.

At 3 months old, Victoria Gray wouldn't stop crying. Blood tests brought devastating news: she had sickle cell disease, a genetic blood disorder that blocks blood flow and oxygen delivery to the body. It causes unbearable pain that Victoria describes as “getting struck by lightning and hit by a truck.”As she got older, Victoria felt increasingly isolated and hopeless. She often spent her kids' birthdays at the hospital, where she received regular blood transfusions. “I felt like I was cheating my children out of their childhood,” she says. “I didn't look forward to a long life. I stopped dreaming. I gave up on school or doing anything … I thought that I was close to dying.”But at age 34, Victoria got a new chance at life. In 2019, she became the first person in the world to receive a revolutionary new treatment for the disease — a gene-editing tool called CRISPR discovered in a UC Berkeley lab, which would go on to win a Nobel Prize just one year later. “It felt like an answered prayer for me,” says Victoria. “CRISPR not only freed me, it freed my children.” This is the third episode of our latest Berkeley Voices season, featuring UC Berkeley scholars working on life-changing research — and the people whose lives are changed by it.Listen to the episode and read the transcript on UC Berkeley News (news.berkeley.edu/podcasts/berkeley-voices).Music by Blue Dot Sessions.Photo courtesy of Victoria Gray; illustration by Neil Freese/UC Berkeley. Hosted on Acast. See acast.com/privacy for more information.

Matters Microbial #121: Phollowing Phage in the Gut Microbiome January 7, 2026 Today Dr. Liz de Ora Ortiz, postdoctoral scholar in the Secor Laboratory at Montana State University, joins the #QualityQuorum to discuss a fascinating new technology that allows investigators to follow bacteriophage infections in live animals.   Host: Mark O. Martin Guest: Liz de Ora Ortiz Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode The fascinating and frustrating (for researchers like me) story of Vampirococcus. A Vampirococcus summary for new #Micronauts. An overview of Agrobacterium, a bacterium about which all micronauts should know (think about genetic engineering in agriculture!). The story of Pelagibacter, very probably the most abundant organism on Earth.    The story of Akkermansia, and its impact on metabolic health and the gut microbiome. An important essay by the late Dr. Elio Schaechter regarding paradigm shifts in microbiology.  Much recommended! A truly wonderful video about bacteriophages and their importance. A simple video explaining the life cycle of lytic and lysogenic bacteriophages. A video from the American Society of Microbiology linking CRISPR and bacteriophages. A review of genes "hitchhiking" in bacteriophages. An introduction to Phollow technology. An overview and discussion of the Phollow technology discussed in this podcast (paywalled).   A Phollow related publication also discussed during the podcast. The Wiles laboratory, where Dr. de Ora Ortiz and colleagues developed the Phollow technology. Dr. Travis Wiles' episode of #MattersMicrobial.  The Secor laboratory, where Dr. de Ora Ortiz currently works. Dr. de Ora Ortiz's LinkedIn profile. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

Why the Antichrist’s global system is no longer a logistical mystery—it's an upgraded retail experience. Pastor Gene Pensiero Find audio, video, and text of hundreds of other prophecy updates at: https://calvaryhanford.com/prophecy Read along with us at https://calvaryhanford.substack.com Follow us on YouTube at https://youtube.com/calvaryhanford — In this week's prophecy update, we take a look at how […]

What do foot massage parties, otters, and AI robot tutors have in common? To find out, tune into our special end-of-year conversation featuring the hosts from TED Talks Daily, TED Radio Hour, TED Business, and TED Tech!Elise Hu, Manoush Zomorodi, Modupe Akinola and Sherrell Dorsey got together to share the biggest ideas dominating their industry and the lesser-known insights they wished garnered more attention. From pushing back against AI advances to sharing the TED Talks that inspired them, Elise, Manoush, Modupe, and Sherrell reflect on 2025 and look ahead to 2026.Conversations MentionedTED Radio HourRay Kurzweil, "Could AI extend your life indefinitely? Futurist Ray Kurzweil thinks so" LINK Victor Riparbelli, “Will AI avatars eventually teach our kids?” LINKPhilip Johns, “Singapore's otters are butting heads with their human neighbors. Can they coexist?” LINKRestoring trust in government, "Move fast...and fix democracy?" LINKTED TalksSitoyo Lopokoiyit in conversation with Jacqueline Novogratz "A story of moral imagination and bold entrepreneurship" LINKSarah Beery, "How AI is unearthing hidden scientific knowledge" LINKScott Loarie (of iNaturalist), "The surprising power of your nature photos" LINKDaniel Zavala-Araiza, "The best way to lower Earth's temperature — fast" LINKJennifer Pahlka, "Coding a better government" LINKPinky Cole (Slutty Vegan), "How I make vegan food sexy" LINKJason Huang, "The high-wire act of unlocking clean energy" LINKJennifer Doudna, "CRISPR's next advance is bigger than you think" LINKJonny Sun, "You are not alone in your loneliness" LINK Hosted on Acast. See acast.com/privacy for more information.

What do foot massage parties, otters, and AI robot tutors have in common? To find out, tune into our special end-of-year conversation featuring the hosts from TED Talks Daily, TED Radio Hour, TED Business, and TED Tech! Elise Hu, Manoush Zomorodi, Modupe Akinola and Sherrell Dorsey got together to share the biggest ideas dominating their industry and the lesser-known insights they wished garnered more attention. From pushing back against AI advances to sharing the TED Talks that inspired them, Elise, Manoush, Modupe, and Sherrell reflect on 2025 and look ahead to 2026.Conversations MentionedTED Radio HourRay Kurzweil, "Could AI extend your life indefinitely? Futurist Ray Kurzweil thinks so" Victor Riparbelli, “Will AI avatars eventually teach our kids?” Philip Johns, “Singapore's otters are butting heads with their human neighbors. Can they coexist?” Restoring trust in government, "Move fast...and fix democracy?" TED TalksSitoyo Lopokoiyit in conversation with Jacqueline Novogratz "A story of moral imagination and bold entrepreneurship" Sarah Beery, "How AI is unearthing hidden scientific knowledge" Scott Loarie (of iNaturalist), "The surprising power of your nature photos" Daniel Zavala-Araiza, "The best way to lower Earth's temperature — fast" Jennifer Pahlka, "Coding a better government" Pinky Cole (Slutty Vegan), "How I make vegan food sexy" Jason Huang, "The high-wire act of unlocking clean energy" Jennifer Doudna, "CRISPR's next advance is bigger than you think"Jonny Sun, "You are not alone in your loneliness" Hosted on Acast. See acast.com/privacy for more information.

What do foot massage parties, otters, and AI robot tutors have in common? To find out, tune into our special end-of-year conversation featuring the hosts from TED Talks Daily, TED Radio Hour, TED Business, and TED Tech!Elise Hu of TED Talks Daily hosted a conversation with Manoush Zomorodi, Modupe Akinola and Sherrell Dorsey, where they discussed the biggest ideas dominating their industry and the lesser-known insights they wished garnered more attention. From pushing back against AI advances to sharing the TED Talks that inspired them, Elise, Manoush, Modupe, and Sherrell reflect on 2025 and look ahead to 2026.Conversations MentionedTED Radio HourRay Kurzweil, "Could AI extend your life indefinitely? Futurist Ray Kurzweil thinks so" Victor Riparbelli, “Will AI avatars eventually teach our kids?” Philip Johns, “Singapore's otters are butting heads with their human neighbors. Can they coexist?” Restoring trust in government, "Move fast...and fix democracy?" TED TalksSitoyo Lopokoiyit in conversation with Jacqueline Novogratz "A story of moral imagination and bold entrepreneurship" Sarah Beery, "How AI is unearthing hidden scientific knowledge" Scott Loarie (of iNaturalist), "The surprising power of your nature photos" Daniel Zavala-Araiza, "The best way to lower Earth's temperature — fast" Jennifer Pahlka, "Coding a better government" Pinky Cole (Slutty Vegan), "How I make vegan food sexy" Jason Huang, "The high-wire act of unlocking clean energy" Jennifer Doudna, "CRISPR's next advance is bigger than you think"Jonny Sun, "You are not alone in your loneliness" Hosted on Acast. See acast.com/privacy for more information.

00:46 The gifts that sparked a love of scienceNature put a call out for readers to tell us about memorable presents that first got them interested in science, or mementos of their life in research. These include telescopes, yeast-themed wedding rings, and... cows' eyes.Nature: The gift that shaped my career in science08:12 “I am the Very Model of a Miniature Tyrannosaur”In the first of our annual festive songs celebrating the science of the past year, we tell the story of a diminutive dinosaur that turned out to be its own species.Nature Podcast: Meet the ‘Wee-rex'. Tiny tyrannosaur is its own speciesNature Video: Hotly debated dinosaur is not a tiny T. rex after all11:43 A very scientific quizAn all-star cast competes for the glory or being the winner of the Nature Podcast's 2025 festive quiz.Nature: Meet the ‘Wee-rex'. Tiny tyrannosaur is its own speciesNature: This company claimed to ‘de-extinct' dire wolves. Then the fighting startedNature Podcast: 3D-printed fake wasps help explain bad animal mimicryNature Video: ‘Aqua tweezers' manipulate particles with water wavesNature Podcast: Sapphire anvils squeeze metals atomically-thinNature Video: Vesuvius volcano turned this brain to glassNature Podcast: Ancient viral DNA helps human embryos developNature Video: Magnetic fibres give this robot a soft gripNature: These contact lenses give people infrared vision — even with their eyes shutNature Video: Is this really the world's largest mirror? Researchers put it to the testNature Podcast: World's tiniest pacemaker could revolutionize heart surgeryNature Podcast: Earth's deepest ecosystem discovered six miles below the seaNature Podcast: Nature goes inside the world's largest ‘mosquito factory' — here's the buzzNature Podcast: Apocalypse then: how cataclysms shaped human societiesNature Podcast: Honey, I ate the kids: how hunger and hormones make mice aggressive25:21 “Hard the Hydrogel is Stuck”Our second festive song is an ode to a rubber duck that was stuck to a rock, thanks to a newly designed, super-adhesive hydrogel.Nature Podcast: Underwater glue shows its sticking power in rubber duck testNature Video: Why did researchers stick a duck to a rock? To show off their super glue28:42 Nature's 10Each year, Nature's 10 highlights some of the people who have helped shape science over the past 12 months. We hear about a few of the people who made the 2025 list, including: a civil servant who stood up for evidence-based public-health policy; the science sleuth who revealed a retraction crisis at Indian universities; and the baby whose life was saved by the first personalized CRISPR therapy.Nature: Nature's 10Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday. Hosted on Acast. See acast.com/privacy for more information.

In this episode of The Brainstorm, we delve into the groundbreaking advancements in gene editing, focusing on its potential to transform healthcare. We explore the shift from treating rare diseases to tackling common killers like cardiovascular disease, and discover how CRISPR technology is paving the way for a new era in medical treatment.If you know ARK, then you probably know about our long-term research projections, like estimating where we will be 5-10 years from now! But just because we are long-term investors, doesn't mean we don't have strong views and opinions on breaking news. In fact, we discuss and debate this every day. So now we're sharing some of these internal discussions with you in our new video series, “The Brainstorm”, a co-production from ARK and Wolf.financial, and sponsored by Public. Tune in every week as we react to the latest in innovation. Here and there we'll be joined by special guests, but ultimately this is our chance to join the conversation and share ARK's quick takes on what's going on in tech today.Key Points From This Episode:CRISPR-based gene editing is moving from treating rare diseases to addressing common conditions like cardiovascular disease.The transition from ex vivo to in vivo gene editing could simplify treatment processes significantly.Lipid nanoparticle delivery is a key advancement enabling in vivo gene editing.The potential market for in vivo gene editing treatments is vast, with significant implications for healthcare costs and patient outcomes.To learn more about WOLF: https://wolf.financialTo learn more about Public: https://public.com/Relevant Links:https://www.ark-invest.com/newsletters/issue-491

As the popularity of online prediction markets grows, correspondent Anderson Cooper sits down with Polymarket founder and CEO Shayne Coplan in his first network television interview. The 27-year-old newly minted billionaire talks about his platform, where users can bet on politics and pop culture, sports and finance, even war and peace, and how all that data can be used to forecast the future. After a three-year U.S. ban, Coplan explains how Polymarket works, and how the company finds itself poised to reenter the U.S. market with backing from Washington, Wall Street and Silicon Valley.  America's next wave of scientific talent may come from Lambert High School, where students used CRISPR to develop a promising new way to detect and treat Lyme disease, which affects nearly half a million Americans each year. Correspondent Bill Whitaker meets these “CRISPR kids” as they take their breakthrough to iGEM—the global biotech Olympics in Paris—and face off against the world's new rising force in biotechnology: China.  Barcelona's 18-year-old soccer phenom Lamine Yamal has captivated fans with his improvisation and flair. Already, he is considered a generational talent and an heir to the great Lionel Messi. Correspondent Jon Wertheim meets Lamine Yamal in his home country of Spain to talk about his rapid ascent ahead of next summer's World Cup in North America. To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices