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In this episode, our host Giovanni Lauricella and our guest Laura Indolfi discuss angels vs. institutional money, Silicon Valley Bank, pitching to the wrong people, psychology that you must have while raising money, her Ted Talk, and so much more. Laura Indolfi LinkedIn PanTher Therapeutics Website Project Medtech Website Project Medtech LinkedIn Giovanni Lauricella LinkedIn
On today's #TheShot of #DigitalHealth Therapy, Jim Joyce and I almost had a "I am lost without you" episode but he made it! In addition in #TheShot first - Jim speaks Italian with our fantastic guest, Laura Indolfi - who is a biomedical engineer turned CEO of PanTher Therapeutics and a TED Fellow. We spent time talking about:
Accredited Investors, an Exciting Syndicate Is Under Way: Click to Learn More Coming from a family of lawyers in Italy, Laura Indolfi was an unlikely candidate to found a tech startup. Yet, her love of engineering and fascination with materials took her to the storied labs at MIT led by Elazer Edelman and Bob Langer. Her startup, PanTher Therapeutics is using off-the-shelf cancer drugs and biomaterials to create a new way to treat cancers that are really hard to treat such as pancreatic cancer, Laura’s first target. Don’t miss this lively interview with a stellar founder. Highlights include: Laura Indolfi Bio How Laura Indolfi Decided She Wanted to Be a Materials Engineer Laura Indolfi Explains Why She Came to the US “Like the first six months I was thinking of probably I will go back to Italy and probably join my family into the law firm. But once you pass that moment and you get adjusted to the space then it was much better.” The Founding Story of PanTher Therapeutics Business Mentors Have Been Very Helpful Could MIT’s Process for Licensing Technology from the Institute’s Labs Be Improved? What PanTher Is Doing and Why It Matters “You end up with 12 times the cancer-killing drug on the tumor as you would get from intravenous application of the same drug.” “We are planning to submit our final application to them [the FDA] beginning of next year, January 2019. That will allow us to start enrolling patients the first quarter of 2019.” “The things that makes me as the CEO of the company very excited is the engagement from the clinical community. We had a partnership with clinical oncologists that they are operating on these patients, coming up to Boston to operate on the pigs.” Sal Daher Reads a Review from a Listener and Asks for Your Review on iTunes Laura’s Indolfi Advice on Fundraising A Major Change at PanTher and What Drove It Laura Indolfi’s Parting Thoughts Arrigo Bodda, This Is for You
Anyone who has lost a loved one to pancreatic cancer knows the devastating speed with which it can affect an otherwise healthy person. TED Fellow and biomedical entrepreneur Laura Indolfi is developing a revolutionary way to treat this complex and lethal disease: a drug delivery device that acts as a cage at the site of a tumor, preventing it from spreading and delivering medicine only where it's needed. "We are hoping that one day we can make pancreatic cancer a curable disease," she says.
Quem já perdeu um ente querido para o câncer pancreático conhece a devastadora velocidade com que ele afeta uma pessoa saudável. Laura Indolfi, bolsista TED e empresária da área biomédica, está desenvolvendo uma forma revolucionária de tratar essa doença complexa e letal: um dispositivo de liberação de fármacos que age como uma gaiola ao redor do tumor, evitando que este se espalhe e liberando medicação somente onde é necessário. "Esperamos que, um dia, o câncer pancreático tenha cura", diz ela.
Tous ceux qui ont perdu un être cher à cause du cancer du pancréas connaissent la vitesse dévastatrice avec laquelle il peut nuire à une personne qui avant cela était en bonne santé. Membre de TED et entrepreneuse en biomédical, Laura Indolfi est en train de développer une méthode révolutionnaire pour traiter cette maladie complexe et mortelle : un dispositif contenant le médicament qui agit comme une cage autour du site de la tumeur, l'empêchant de s'étendre et libérant le médicament seulement quand cela est nécessaire. « Nous espérons qu'un jour nous pourrons faire du cancer du pancréas une maladie curable, » dit-elle.
Todos aquellos que han perdido a un ser querido a causa del cáncer de páncreas conocen la velocidad devastadora con la que puede afectar a una persona sana. Laura Indolfi, Becaria TED y empresaria biomédica, está desarrollando un método revolucionario para el tratamiento de esta enfermedad compleja y mortal: un dispositivo que suministra el fármaco que actúa alrededor del tumor obstruyendo su propagación, y lo libera sólo cuando es necesario. "Esperamos que un día podamos catalogar al cáncer de páncreas como una enfermedad curable", dice Laura.
Jeder, der einen geliebten Menschen an Bauchspeicheldrüsenkrebs verloren hat, kennt die verheerende Schnelligkeit, mit welcher dieser eine ansonsten gesunde Person treffen kann. Laura Indolfi, TED Fellow und biomedizinische Unternehmerin, entwickelt ein revolutionäres Verfahren, um diese komplexe und tödliche Krankheit zu behandeln: Ein Medikamenten-Verabreichungssystem, das als Käfig an der Seite eines Tumors fungiert, um dessen Ausbreitung zu verhindern und Medikamente nur dorthin zu liefern, wo sie benötigt werden. "Wir hoffen, dass wir Bauchspeicheldrüsenkrebs eines Tages zu einer heilbaren Krankheit machen können", sagt sie.