Podcasts about Pancreatic cancer

June 24th, 2006. Historic Fort York, Toronto. Twenty-two songs, and buried at number fourteen is a track The Tragically Hip only ever played nine times.That is the version we spin. Same night they pulled '38 Years Old' out of the vault for the first time since July of 1995. Nine plays for 'No Threat', per Hipbase and setlist.fm, and one of those nine got audited live on this stream. There was an entry claiming November 15th, 1991. Andrew went after it, Steve pulled the tape down to check, and the correction went in while the mics were still hot.'No Threat' opens "Yer Favourites", the November 2005 double disc where fans voted on every track except the two nobody had heard yet. This one, and 'The New Maybe' closing disc two. Adam Kasper made both, the same man who made "In Between Evolution" the year before. Track one is the brand new song. Track two is 'Grace, Too'. Kevin has a word for that sequencing decision, and the word is bold.It landed at 85 on the TTHTop40 Countdown, between 'Daredevil' and 'Sherpa'. Then the poll came back from the Facebook group with a stack of loves, which was nobody's prediction at this table, plus eight percent who came right out and said they dislike it. Steve did not vote. Steve tells us where he would have landed, and it opens something bigger than the song: what do you do with a band you love and songs you don't? He has a list. He is not sorry about the list.Then there is the guitar. Jeff from Vaughan puts it in the chat first, that it is the guitar that doesn't work here, and Kevin has been circling the same thing all week. A chord that goes somewhere your ear refuses to follow. He can tell you which side of the mix it comes from and which of the two of them is playing it.WHAT ELSE IS IN HERE• Yelly Gord. Andrew's name for the thing that starts here and does not stop, straight through 'Yer Not the Ocean' and into a version of 'Blow at High Dough' that is barely a word any more. Where it came from, and which album this song belonged on instead.• Kevin catches the flip. First person the whole way through, and then for one line it isn't, and there is a woman in the room.• The last thing Gord says in the song. Nobody here can explain it. Three theories, no verdict, and one line jD reads out that stops everybody cold: you die to your fans one window at a time.• Andrew went hunting the origin story. Nine or ten full shows from 1996, chasing a rant that is supposed to be the seed of this song. He did not find it. He found something else about peacekeeping that he cannot now unhear.• The Hip headlined the first two concerts ever held at the Air Canada Centre. Steve knows who opened, and who played the third night.• The anniversary weekend. jD in Kingston for Springer Market Square, murals and painted guitars all over a town that does not normally do it up. Steve stretched it over three days in Toronto and got a west end blackout two songs into the last show. Kevin was in Ireland.• The live record, and the two songs on it that are not live. Andrew has a fix.• End of summer picks. Steve's 'The Dire Wolf' and a whole summer in Kingston in 2002. Andrew's '11th Fret', a hangover song and he means that kindly. Kevin's 'Three Pistols', Tom Thomson and Algonquin Park. Steve's first answer was not one of theirs at all, and he owns it on air.Next week the wheel lands on 'Putting Down' from "Music @ Work". Which the band played at Fort York that same June night in 2006, four songs before this one. So there's that.THE PANEL• Kevin from Sarnia. First time at the table. He was buying every one of these records the week it came out and cannot remember buying this one, which tells you something. Plays in a cover band called 402 West, named for the highway between London and Sarnia.• Andrew from Winnipeg. Back again, and the closest thing this show has to a research department. Plays bass in Crooked Ice, whose record is "Dark Stars", and he cut the video too. His radio show and podcast is Soup Full of Radio.• Steve from Toronto. Fourth time on a jD show inside a month, which he points out himself. At Fort York in 2006, in the building in Kingston in 2016. He rides for the Tragically Clipped, a Princess Margaret Cancer Foundation team that began as an act of spite between two friends and has raised over $200,000 since. What happened to one of his riders at a rest stop is worth the wait.GEDFEST TORONTO - SATURDAY, OCTOBER 17The Horseshoe Tavern, with Grace, 2. Every dollar goes to Campfire Circle and the Murphy Family Fund in Precision Medicine in Pancreatic Cancer. Tickets through facebook.com/GEDfestYYZ.YER LETTEROnce a month, the whole network in one email. Where the shows are headed, what got made, and what did not fit anywhere else. Free. subscribe.tthpods.comTHE TIP JARIf the shows are worth something to you, buymeacoffee.com/tthtop40.FIND USHome: home.tthpods.comEmail: jd@tthpods.comFacebook community: community.tthpods.comInstagram: @tthpodsYouTube: youtube.com/@tthpodsYer Letter: subscribe.tthpods.comMORE THE TRAGICALLY HIP ON SHUFFLE LIVE STREAM'Tiger The Lion': https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/718fe20e-83d6-4c69-86eb-cc2b4af02834'Emperor Penguin': https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/a2f229b2-b5fc-41e4-8d78-632080d31a3b'Pigeon Camera': https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/49a9167c-6f8d-4641-8306-959189b38ec8Live performance counts, dates, and the Fort York set list come from Hipbase and setlist.fm, as cited on the stream. Production credits from the "Yer Favourites" liner notes.#TheTragicallyHip #YerFavourites #TTHOnShuffle #GordDownie #TheHip #TTHPodsSupport this podcast at — https://redcircle.com/tthtop40/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Broadcast from KSQD, Santa Cruz on 8-27-2026: Preparing for extreme heat requires a few days of controlled hyperthermia to boost blood plasma volume and trigger heat shock protein production. Dr. Dawn cites research showing that daily 40-minute treadmill sessions in an 80-degree room followed by 40-minute hot baths for six days—or simply an hour daily in a 40°C bath for four days—produces 75-80% of full acclimatization before a heat-zone trip. Five red flags warrant an ER trip for abdominal pain: pain worsening with coughing or car bumps (peritonitis), lack of gas passage with nausea (bowel obstruction) especially with dark green bilious vomiting, yellowing whites of eyes (bile duct obstruction with sepsis risk), tarry black shiny stool (bleeding ulcer versus coffee-ground vomit), and dizziness with pain (possible leaking aortic aneurysm). Dr. Dawn urges any man who has smoked over 100 lifetime cigarettes to request the Medicare-covered abdominal ultrasound screening for aortic aneurysm, noting only 4% of eligible men currently receive it. Quaternary ammonium compounds (QACs) fill nearly half of disinfectants, surface sanitizers, and cleaning wipes, with use surging after 2016 FDA antimicrobial bans and the COVID pandemic. A 2023 Environmental Science and Technology review documented reproductive toxicity, hormone mimicking, dermal and respiratory irritation, and disruption of mitochondrial oxidative phosphorylation. Dr. Dawn recommends apple cider vinegar and water as a safe household cleaner and directs listeners to EWG.org for QAC-free product listings. A UK Biobank study of 65,000 people born in the 1940s-50s exploited WWII sugar rationing (eight ounces weekly through 1953) as a natural experiment. Those exposed to less sugar before age two had 20% lower dementia risk with 2.5-year delayed onset, and protection held even for those whose low-sugar exposure was purely in utero—underscoring the importance of avoiding added sugars in baby foods during the first 1,000 days. A Coast Guard rescuer's suicide following years of headaches and mood swings prompted his teenage daughter's high school survey of 77 surfmen, most of whom described the same TBI symptoms. Repeated boat impacts hitting waves at 6G at the deck translate to roughly 60G at the sailor's head—more violent than car crashes—prompting the Coast Guard's first official acknowledgment of the wave-pounding brain injury problem. Anopheles stephensi, a hardy South Asian malaria vector that thrives in urban environments and survives dry seasons, has spread from Djibouti (2012) through Yemen, Ethiopia, Sudan, and Kenya. Genomic analysis reveals distinct genetic clusters as it advances, all largely resistant to standard mosquito-control chemicals used in netting and sprays. Dr. Dawn ties this to broader arthropod-borne disease expansion in the U.S. from climate warming, and defends deer culling as tick-vector reduction. Dr. Dawn recommends the PREVENT calculator (using blood pressure, cholesterol, age, sex) as the starting point for coronary risk assessment. Coronary calcium scores are most useful for those in the borderline/intermediate range (3-9% ten-year risk)—a score above age-normal warrants reconsidering statin therapy—but add little value at high risk (where zero calcium doesn't rule out non-calcified plaque) or in older patients. An update on shingles vaccination and dementia: Geldsinger's 2025 Welsh natural-experiment study (exploiting birthday-based Shingrix rollout cutoffs) showed a 20% dementia reduction, since replicated in Canada, Australia, and Scotland. New Hebrew University data suggests giving Shingrix four weeks apart (Dr. Dawn cautions against this shortened interval) may stabilize cognition in existing Alzheimer's patients. The proposed mechanism involves boosting regulatory T-cells that dampen chronic neuroinflammation—also explaining why BCG (400% dementia reduction in bladder cancer patients) and flu vaccines show similar protective effects. An oral KRAS-inhibiting drug, daraxonrasib, doubled median survival in 500 patients with metastatic pancreatic cancer from about six months to 13.2 months by blocking proteins produced by the historically undruggable KRAS gene—the first major advance for a cancer where metastatic diagnosis has meant near-immediate death sentence.

Headlines: – Welcome to Mo News + Dolly Parton's Secret Song (02:00) – Flash Flood On Nepal-Tibet Border Kills More Than 160, Hundreds Of Tourists Missing (06:20) – Meta Reaches $18 Billion Settlement With 48 States Over Child-Safety Claims (10:30) – FDA Approves Drug for Pancreatic Cancer (20:10) – Bill Gates Proposes Major Limits On AI Development (22:30) – Schools Are Assigning Fewer Novels. Are Excerpts Just As Good? (29:20) – Prince Harry and Meghan Land In UK Days After Announcing Move (32:20) – On This Day In History (35:45) Thanks To Our Sponsors:  – Monarch - 50% off your first year | Code: MONEWS – Factor - 50% off your first box | Code: monews50off –⁠ Industrious⁠ - Coworking office. 50% off day pass | Code: MONEWS50 – LMNT | Free Sample Pack with any LMNT drink mix or 12oz cans purchase – ⁠Boll & Branch⁠ – 20% off first order, plus free shipping | Code: MONEWS

Today's Headlines: We're almost to the weekend and we're starting off with tech and medical science. Meta settled its youth addiction trial for $17 billion paid over ten years across 47 states — with new safety requirements for minors including time limits, night mode, and hidden like counts. Of course the company's stock went up after the settlement, which tells you everything about who won. Bill Gates published a 5,784-word AI warning blog post saying there is "no plan" for the transition to the AI era, too late the hero, Bill. In medical news, the FDA approved a new pancreatic cancer drug that nearly doubles survival time compared to chemo alone — genuinely significant given that disease kills 7 out of 8 patients within five years — though at $40,000 a month, accessibility will be an issue. On the food safety beat, an emergency recall was issued for nearly 30,000 pounds of Argentinian beef sold in Florida and Texas, as Trump simultaneously told Glenn Beck he wants to reduce regulations on beef processing plants. During that same Glenn Beck call, Trump attempted to mourn Dolly Parton and ended up mostly saying she liked him, sure. Meanwhile, The CIA director's Moscow visit turned out to involve Russian intelligence officials rather than Putin directly, with the stated purpose being to warn Russia not to attack NATO — while Iran and Russia simultaneously announced a $25 billion nuclear energy deal and a Putin-Pezeshkian summit next week, so it's going great. In bizarre election news, a federal prisoner currently serving time in New York until 2036 somehow got enough votes in Alaska's primary to run for the House in November, listing a South Dakota address and his mother's New York phone number on his filing paperwork, because Alaska's elections are genuinely something else. And finally, a massive mudslide on the Nepal-Tibet border has killed over 150 people with hundreds more missing including 47 American tourists, rescue helicopters unable to land, and climate change-driven permafrost thaw making the damage significantly worse. Resources/Articles mentioned: CNBC: Meta settles social media addiction case with California, other states for $16.7 billion WSJ: Three Takeaways From Bill Gates's 5,784-Word Warning on AI: ‘There Is No Plan' Axios: Scoop: Senate Republican investigates Flock cameras  WSJ: FDA Approves Drug for Pancreatic Cancer in Milestone for Treatment of Deadly Disease Wide Open Country: Emergency Recall Declared for Beef Imported by Trump Administration US News: Trump Says He Will Look at Beef Processing Regulations, as Farmers Fight Tariff Plan France 24: Kremlin says CIA chief met Russian counterparts, not Putin, in Moscow AP News: A federal prisoner with no clear ties to Alaska advances in primary for the state's US House seat NBC News: Hundreds missing after flood hits Nepal-Tibet border, 157 bodies recovered Subscribe to the Betches News Room and join the Morning Announcements group chat. Go to: betchesnews.substack.com Morning Announcements is produced by Sami Sage and edited by Grace Hernandez-Johnson Learn more about your ad choices. Visit megaphone.fm/adchoices

Thursday, August 27. The seven stories you need to know today.Read today's briefing.

The Food and Drug Administration approved a new medication to treat pancreatic cancer. In trials, it extended the survival rate of patients by a median of 13.2 months. Dr. Brian Wolpin from the Dana Farber Cancer Institute explains how the drug works and what it could mean for the future of cancer treatment.Then, a recent study found that at least a quarter of former NFL players who died had chronic traumatic encephalopathy, or CTE. Chris Nowinski, CEO of the Concussion Legacy Foundation shares more about the findings and how they could impact the upcoming football season.And, in Nepal, first responders are searching for survivors after a massive flash flood killed at least 300 people. Suraj Sigdel, Nepal Country Director for Mercy Corps, describes the work he and others are doing on the ground.See pcm.adswizz.com for information about our collection and use of personal data for sponsorship and to manage your podcast sponsorship preferences.NPR Privacy Policy

For the Good of the Public brings you news and weekly conversations at the intersection of faith and civic life. Monday through Thursday, The Morning Five starts your day off with scripture and prayer, as we also catch up on the news together. Throughout the year, we air limited series on Fridays to dive deeper into conversations with civic leaders, thinkers, and public servants reimagining public life for the good of the public. Today's host was Michael Wear.  Thanks for listening to The Morning Five! Please subscribe to and rate The Morning Five on your favorite podcast platform. Learn more about the work of the Center for Christianity and Public Life at www.ccpubliclife.org. Today's scripture: Colossians 3:1-10 (ESV) News sources: https://www.nytimes.com/2026/08/26/technology/meta-settlement-social-media-addiction-lawsuit.html  https://www.wsj.com/health/pharma/fda-approves-drug-for-pancreatic-cancer-in-incredible-moment-for-deadly-disease-28638f15?mod=hp_lead_pos1  https://www.washingtonpost.com/politics/2026/08/26/trumps-endorsement-helps-darline-graham-win-south-carolina/  https://www.nytimes.com/2026/08/25/arts/music/dolly-parton-dead.html?eafs_enabled=false  https://www.christianitytoday.com/2026/08/dolly-parton-always-love-you-music-self-respect/  Join the conversation and follow us at: Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@michaelwear⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, @ccpubliclife Twitter: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@MichaelRWear⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, @ccpubliclife and check out ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@tsfnetwork⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Music by: King Sis #politics #faith #prayer #scripture #news #tech #Meta #safety #FDA #cancer #health #DarlineGraham #SouthCarolina #Senate #elections #DollyParton Learn more about your ad choices. Visit megaphone.fm/adchoices

A new pill that can treat pancreatic cancer has been approved by the FDA, but the cost of the medicine is causing some people concern.Meta's multi-billion dollar settlement with 47 states over social media addiction could result in some major changes to social media rules, especially for children. Nicholas Thompson, CEO of The Atlantic, joins with more.Dolly Parton was known for her unique style, and many remember her as a fashion trailblazer despite the early pushback she received. Adriana Diaz breaks down her impact on fashion.NASA administrator Jared Isaacman joins "CBS Mornings" to discuss the space race with China, the agency's plan to build a moon base at the lunar south pole, and the next Artemis mission.As "Big Brother" airs its 1,000th episode, host Julie Chen Moonves breaks down what makes the show so popular. Jonathan Vigliotti reports.A Marine veteran who lost his legs to an IED blast while being deployed in Afghanistan in 2012 found a new purpose in life as an adaptive training coach and ultramarathoner. Mike Egan talks to Jason Allen about competing in an ultramarathon where he went viral for dragging his wheelchair through mud on the final lap of the race.Singer-songwriter Alex Warren sits down with Anthony Mason to talk about his sophomore album, WILDCHILD, the loss of his parents and how songs have been the soundtrack to his emotions.

P.M. Edition for Aug. 26. Tech reporter Meghan Bobrowsky tells us why the Meta settlement could change how teenagers use some of the world's most popular apps. Plus, the FDA approves a milestone therapy for pancreatic cancer. WSJ reporter Xavier Martinez discusses how the nearly $40,000-a-month drug from Revolution Medicines could change patient outcomes of one the deadliest cancers. And the FBI shuts down a sprawling hacking network linked to China that targeted NASA, the Federal Reserve and critical infrastructure. Sabrina Siddiqui hosts. Sign up for the WSJ's free What's News newsletter. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Hey, it's jD here. August 20th, 2026. Bath, Ontario. A stone coach house west of Kingston that the band turned into a recording room, where "Phantom Power", "Music @ Work", "We Are The Same", and "Man Machine Poem" were all made. Ten years to the day since the last show. This is the last one. Yer Hipstories: Reflections From The Final Tour ran the length of the Man Machine Poem Tour, city by city, Victoria east to Kingston, and it ends here, in the room where the last record was made. Three fans at the table, and not one of them tells August 20th the same way. One was on the floor. One was in the square with 25,000 people. One was on his couch in Brockville with a bottle of wine and a good reason.

June 16th, 2000. The first of only 89 times The Tragically Hip ever played 'Tiger The Lion' live, and the last one is a long way off from there.Eighty-nine, per Hipbase and setlist.fm. That's the whole run, first to last, June 2000 to a night in November 2009. Fifteen of those as an opener, which makes sense to everybody at the table. Fifteen as an encore, which makes sense to nobody. It never went out as a single. The record it sits second on went two times platinum in Canada and took home the Juno, and it's the second of the two Steve Berlin made with the boys. 'Tiger The Lion' landed at number 65 on the TTHTop40 Countdown and not one person in this room is at peace with that.Then there's the poll. Just over half the Facebook group came back with love it, which the panel did not see coming, and close to eight in ten landed at like it or better. For a track this strange, sitting where it sits, that's a number worth chewing on. Somebody in the comments wanted an option between love it and like it. Jeff has a fix for that, and it's better than extra medium.Duxoop from Toledo dropped a question in the chat that stopped the table cold. What is that opening noise? Jeff had already gone looking earlier in the week, so we get the answer live: what the sound actually is, who made it, and the instrument buried underneath it that most of the congregation has never once picked out. Twenty-six years of listening and there it is, right in front of everybody the whole time.We spin the MuchMusic Intimate & Interactive version from that same summer, Chris Brown and Kate Fenner on stage with them, and then Jeff comes back with something none of us caught. Gord is reciting under Rob's outro. Not scatting. Reciting. From a poem, by a Canadian poet Gord loved enough to record in full for a tribute record years later. And the hotel that poem is named for is a ten minute walk from where Jeff grew up.WHAT ELSE IS IN HERE• John fucking Cage. Greg pulls the passage Gord was reading and puts it in a bigger frame, and it turns out to be about a whole lot more than music. Jeff, meanwhile, has listened to some John Cage and has thoughts about it that are not kind, and he says them anyway.• A song with no chorus. Not a bridge in the middle either, just a break. So how does it hook anybody? Dave takes a run at that one, and at what Rob does on the outro instead of what any other guitar player would have done with all that room.• Greg's theory that the catalogue splits into four groups, that this is where the art rock properly starts, and that this cut sits in the top five heaviest songs the band ever recorded. Bombs dropping. His words.• The sequencing. 'My Music At Work' into 'Tiger The Lion' into 'Lake Fever'. Dave would have moved it. Greg would not have moved a thing.• Where the lyrics turn. Dave on the shift that starts around this record and how much harder Gord makes you work from here on in, and Greg on the mouth shapes and the dancing and writing words that sound right before they mean anything.• First listens. A leaked MP3 that took seven hours to download. A boombox on a deck in Tacoma running the record two days straight. A Calgary apartment full of diehards filing this one under wait, what.Next week the wheel lands on 'No Threat', one of the two new tracks tucked onto "Yer Favourites". Brand new panel, brand new song.THE PANEL• Greg from Tacoma. Met the boys back around 'New Orleans Is Sinking', has seven to ten copies of every CD and gave most of them away. He makes music with AI under Hadees Market Music, spelled H-A-D-E-E-S, after his grandparents Hazel and Ira D.• Jeff from Belleville. Third time in the chair. Belleville sits on the Bay of Quinte, which is exactly why the last ten minutes of this one belong to him.• Dave from Halifax. First time at the table, and a musician, which shows the second the outro starts.GEDFEST TORONTO - SATURDAY, OCTOBER 17The Horseshoe Tavern, with Grace, 2. Every dollar goes to Campfire Circle and the Murphy Family Fund in Precision Medicine in Pancreatic Cancer. Tickets through facebook.com/GEDfestYYZ.THE TIP JARGreg asked for this link on mic, so here it is. If the shows are worth something to you, buymeacoffee.com/tthtop40.FIND USHome: home.tthpods.comEmail: jd@tthpods.comFacebook community: community.tthpods.comInstagram: @tthpodsYouTube: youtube.com/@tthpodsYer Letter: subscribe.tthpods.comMORE THE TRAGICALLY HIP ON SHUFFLE LIVE STREAM'Emperor Penguin': https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/a2f229b2-b5fc-41e4-8d78-632080d31a3b'Pigeon Camera': https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/49a9167c-6f8d-4641-8306-959189b38ec8'Gus: The Polar Bear From Central Park': https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/68d2991b-9074-43ef-bd71-aa832c59a787Live performance counts, dates, and chart details come from Hipbase and setlist.fm, as cited on the stream. Album details from the "Music @ Work" credits.#TheTragicallyHip #MusicAtWork #TTHOnShuffle #GordDownie #TheHip #TTHPodsSupport this podcast at — https://redcircle.com/tthtop40/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

COVID Mandate Moral Injury, mRNA Cancer Treatment, Pancreatic Cancer Surge, Natural Thyroid Access, Cereal Toys Return, Michael Boldin, Tenth Amendment Center, Constitution Enforcement, Constitution's Original Purpose, Franklin's Welfare Warning, 17th Amendment, and MORE! https://robertscottbell.com/covid-mandate-moral-injury-mrna-cancer-treatment-pancreatic-cancer-surge-natural-thyroid-access-cereal-toys-return-michael-boldin-tenth-amendment-center-constitution-enforcement-constitution/ Purpose and Character The use of copyrighted material on the website is for non-commercial, educational purposes, and is intended to provide benefit to the public through information, critique, teaching, scholarship, or research. Nature of Copyrighted Material Weensure that the copyrighted material used is for supplementary and illustrative purposes and that it contributes significantly to the user's understanding of the content in a non-detrimental way to the commercial value of the original content. Amount and Substantiality Our website uses only the necessary amount of copyrighted material to achieve the intended purpose and does not substitute for the original market of the copyrighted works. Effect on Market Value The use of copyrighted material on our website does not in any way diminish or affect the market value of the original work. We believe that our use constitutes a 'fair use' of any such copyrighted material as provided for in section 107 of the U.S. Copyright Law. If you believe that any content on the website violates your copyright, please contact us providing the necessary information, and we will take appropriate action to address your concern.

Joining the Project Purple Podcast from Rhode Island, pancreatic cancer survivor and author Marla Schreffler shares a story shaped by intuition, timing, and persistence with host Dino Verrelli. A school psychologist by profession, Marla reflects on how her life before diagnosis was defined by overall health and a heightened awareness of changes in her body: an awareness that ultimately played a key role in how her cancer was discovered. In April 2024, Marla shares how she began noticing subtle but escalating changes with her body, including blurry vision, dry mouth, and unexpected weight loss. What initially appeared to be just a diabetes diagnosis quickly evolved into something far more complex, as testing revealed a tumor on her pancreas, which was later discovered to be cancerous. In those early moments, Marla recalls confusion and shock, but also a growing sense that something had not been right for some time. Trusting her instincts and pushing for further evaluation proved critical, ultimately leading to an early diagnosis that allowed for swift action. She went on to complete chemotherapy, radiation, and the Whipple procedure, where the tumor was later found to be completely dead, and she is now in remission. Throughout her experience, Marla emphasizes the importance of patient advocacy and communication within the healthcare system. A researcher at heart, she took it upon herself to deeply understand her diagnosis and treatment options, asking questions, seeking clarity, and working collaboratively with her care team to create moments of comfort, even in the most vulnerable settings. From small acts of agency she insisted on to larger conversations about how patients are treated and heard, Marla reflects on the many ways control can be reclaimed even in the face of cancer. Following her Whipple procedure, she channeled her experience into writing Status: Warrior Woman, a book inspired by her journey and designed to help others better understand what to expect and how to cope. At its core, her message is clear: advocating for yourself can make all the difference. Marla's book is available through her website at www.pancreaticsurvivorwarrior.org and on Amazon. Subscribe to the Project Purple Podcast for more stories from the pancreatic cancer community! To learn more or donate to Project Purple's mission of a world without pancreatic cancer, visit www.projectpurple.org.

In this episode of Oncology On the Go, CancerNetwork® spoke with Frank McCormick, PhD, about the arc of KRAS-targeted drug development over his 40-year career. He explained why KRAS was long considered “undruggable.” He walked through the origins of the National Cancer Institute's RAS Initiative, which he helped lead starting in 2013, and how that effort produced several of the drugs now advancing through clinical trials for pancreatic cancer.A central moment of the conversation centers on the phase 3 RASolute-302 trial (NCT06625320) data, which showed that daraxonrasib nearly doubled overall survival compared with standard of care in pancreatic cancer. McCormick described this as a turning point that transformed pancreatic cancer from a historically difficult indication into one now seeing a wave of new drug development.McCormick also discussed his vision for cancer prevention. He described a roughly 20-year window between initiating KRAS mutations and clinical disease, and outlined a future in which a safe, well-tolerated KRAS inhibitor could be taken periodically to eliminate precancerous lesions before they progress, potentially preventing KRAS-driven cancers from developing at all.Additionally, he addressed practical considerations for treating clinicians: the feasibility of moving RAS inhibitors into earlier lines of therapy, and the biology oncologists, pharmacists, and genetic counselors should understand about differing KRAS allele subtypes.McCormick is a professor in the Helen Diller Family Comprehensive Cancer Center and holds the David A. Wood Distinguished Professorship of Tumor Biology and Cancer Research at the University of California, San Francisco (UCSF). He has researched KRAS for 40 years and helped lead the NCI RAS Initiative. He was recently named the inaugural recipient of the Stephenson Global Prize from the Stephenson Global Pancreatic Cancer Research Institute.ReferenceDaraxonrasib demonstrates unprecedented overall survival benefit in pivotal phase 3 RASolute 302 clinical trial in patients with metastatic pancreatic cancer. News release. Revolution Medicines Inc. April 13, 2026. Accessed August 19, 2026. https://tinyurl.com/44t5vh5d

August 20th, 2016. The Rogers K-Rock Centre, Kingston, Ontario. Thirty songs. Three encores, which was not a thing they did. And a country that put down whatever it was holding.Ten years later, jD asked fifteen people one question. Not what they made of it. Not where it ranks. Just this: where were you.The answers do not go where you would expect. An airplane hangar outside Olympia, Washington. A garage door in the country north of Superior with fifty people camped in the yard. A smoker in Calgary that had been running since sunrise. A lakeside deck in upstate New York with a bottle of Macallan 12 on it and a great blue heron that keeps turning up in the shape of an album cover. An arena in Chicago where a man from Detroit stood in a Gord Downie shirt underneath a Tigers jersey, missing the whole thing on purpose, waiting to find out whether two sentences he had typed five days earlier had reached anybody.They had. That is all yer getting.Who's HereAdam from Tampa had never seen The Hip play a note and owned five of the records. At 7:55 he told his houseguests he would be back in either five minutes or two and a half hours, went upstairs, and typed the words CBC and The Tragically Hip into a search bar. What he did the following morning cost him the next four years.Andy from London was three weeks deep into Scotland with a speaking gig in Pennsylvania waiting on the Monday. He flew home without his family for exactly one day. Where he watched it, and who was running the sound there, is the part that still gets him.Brian from Canastota got hooked by a Saturday Night Live performance in 1995 and never came unhooked. Bose rig on the deck, the lake in front of him, and a heron that has been showing up in a very particular silhouette for years. His wife found him out there at two in the morning.Brock from Kitchener was in the lower bowl. A ticket scanner went down and he ended up sitting inside a nearly empty K-Rock Centre while eight thousand people waited outside. Ten years on he has still never watched the broadcast. Not once, not one song.Colin from Winnipeg lost his mother and had his first child inside the same fortnight, and had to move a funeral to do it. He watched with a newborn who is ten years old now. He has a plan for the rewatch, and it involves all three kids.Dan from Buffalo and Colleen from Buffalo drove in from the Hamilton show with no tickets, no expectations, and their phones switched off at the border. Dan wandered down to look at a boat show at half past nine in the morning and got into a line without asking what the line was for. He was number twenty-eight.Duxoop from Toledo watched at home, alone, so that nobody could see him cry, pulling CBC down through a Windsor channel on Ohio cable. He knew twelve of the thirty songs that night. He is up to nineteen now, and the way he counts them is not the way you would count them.Greg from Tacoma spent the evening at his mother Rosalie's 79th birthday party in an airplane hangar, slipping off to a corner every ten minutes with a phone and no headphones. What he heard inside 'Grace, Too' that night he has never stopped hearing, and the people standing beside him in that hangar are a large part of why.Janice from Kitchener stopped for a photo at the Welcome to Kingston sign, signed the banners downtown, and walked into the arena at the exact moment it stopped letting anybody else in. She has a theory about how many people are eventually going to claim they were in that room.Jimmy from Detroit had tickets for the London and Toronto shows, and a promise to his wife that put him in Chicago on the 20th instead. Five days out he sat down and wrote two sentences on a message board. He will go to his grave believing somebody read them.Joanne from Thunder Bay had seen the August 12th show in Toronto and could not get to Kingston. A friend rigged a projector onto a garage door out in the country and fifty people camped in the yard to watch it. One song landed harder than everything around it, and it was not the closer.Spencer from Calgary made three racks of ribs, a couple dozen perogies by hand, and a house rule about side conversations. Gold glitter letters stuck to the fridge spelling out the songs he was hoping for. Then he walks the setlist album block by album block, and a decade later the surprises still surprise him.Steve from Toronto got a single ticket half an hour after they went on sale and watched from ten rows back. He has the sharpest disagreement in the whole episode, and it is not about the band. It is about whether the people watching it and the people inside it were even at the same event.Todd from Fort Mac says the words Fort Mac and 2016 and everybody already knows he means the fire. He watched at his grandfather's house in Louisdale, Cape Breton, with the family in from out west. It was the last time all of them were in that room together.What They Said"I'll start with the punchline, which was I was in an airplane hangar weeping."  - Greg from Tacoma"I went by myself, but I was not alone."  - Andy from London"When you're watching it on TV and Gord's breaking down at the end of the song, you feel completely helpless. But when you're at the show and that happens, you just start making as much noise as you know how to make to help your guy pull through."  - Steve from Toronto"To me, it's a celebration of Canadian culture. And I know that was never the intention, but it's just always what it turned out to be."  - Todd from Fort MacAbout That NightThirty songs at the Rogers K-Rock Centre. 'Fifty-Mission Cap' into 'Courage', 'Wheat Kings', and 'At the Hundredth Meridian' - four songs in and the whole country was already accounted for. Then 'Tired as Fuck', uncensored, on the national broadcaster. Then a thunderstorm nobody had been warned about. Then 'My Music at Work', 'Lake Fever', 'Toronto #4', and 'The Last of the Unplucked Gems', which is not a setlist, it is a dare. Three encores, closing on 'Ahead by a Century'. Setlist confirmed via setlist.fm.Fifteen people, one date, and not one of them tells it the same way. That is the whole point of this show, and Kingston is where it lands.GEDfest Toronto 2026Saturday, October 17th, 2026. The Horseshoe Tavern, Toronto, with Grace, 2 on the stage. GEDfest raises money for Campfire Circle and the Murphy Family Fund in Precision Medicine in Pancreatic Cancer, and this community has put nearly $40,000 toward causes like these since 2018. Tickets and details: facebook.com/GEDfestYYZThe CommunityYer Letter lands once a month with everything happening across the network. Subscribe at subscribe.tthpods.com. The Facebook group is roughly 7,500 fans deep and still climbing at community.tthpods.com. Leave yer own Hipstory any time - jD reads every one.Home: home.tthpods.comEmail: jd@tthpods.comInstagram: @tthpodsYouTube: youtube.com/@tthpodsTip JarEditing is hard and the battery needs charging. Buy jD a coffee at buymeacoffee.com/tthtop40More From The Final TourYer Hipstories: Reflections From The Final Tour - Ottawa: redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/7fb753ff-654b-4be4-ab44-3cbae3b7a68bYer Hipstories: Reflections From The Final Tour - Hamilton: redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/fae76ee3-738f-4007-80c8-7140729bb295ClosingThank you to Adam, Andy, Brian, Brock, Colin, Dan, Colleen, Duxoop, Greg, Janice, Jimmy, Joanne, Spencer, Steve, and Todd. Fifteen people handed over the most specific night of their lives and asked for nothing back. So there's that.#TheTragicallyHip #GordDownie #TTHPods #HipFans #CanadianMusic #InGordWeTrustSupport this podcast at — https://redcircle.com/tthtop40/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

August 18, 2016. Ottawa, the second last night, and two fans who were in that building take jD back inside - ten years to the day.Thursday, August 18, 2016. The Canadian Tire Centre, out past the ring of car dealerships in the west end, and The Tragically Hip had two nights left. Kingston was already a pipe dream by then. For most of the country, Ottawa was the last chance.Ten years to the day, jD sits down with two fans who were in that room. Shawn from Ottawa, who has been in this community since he was sixteen. And Justin from Bridport, who you know from Discovering Downie, and who only got to Ottawa because a stranger with long hair heard "Yer Favourites" playing over the PA at a dirt track in Vermont.Two ticket stories, and neither one lands where you would guess. Shawn's shows up in his inbox, out of a presale nobody has ever really talked about in public, and there is something waiting in the will call envelope that nobody warned him about. Justin's shows up from a man whose name he did not have yet. He said yes first and introduced himself second.The songs: Justin starts to say 'Grace, Too', catches himself, and lands somewhere else. Shawn takes a deep cut off "In Between Evolution", the first record that ever got its hooks into him. They both land on 'Summer's Killing Us', and Ottawa turned out to be the last place The Tragically Hip ever played it.Then they walk the set list, and it is not the greatest hits argument you would expect. 'Opiated' out of nowhere. Four from "In Between Evolution" and four from "Day for Night", and the moment mid-set when Shawn worked out that none of those songs were going to make it to Kingston. Justin honoured Gord's wishes and kept the phone in his pocket, right up until he didn't.There is the morning of the announcement, too. Justin spent it alone in a car in Vermont, listening to a DJ who could not finish a sentence, with nobody to call. Shawn spent it in a country where everybody already knew before he was properly awake. Ten years later, hearing each other's version, that gap is the thing that gets them both.And then there is what happened after the lights came up, which involves two flights of stairs, a room that was not supposed to be a party, and a conversation outside it with somebody's grandfather. That one belongs to Shawn.Two nights later, one of them was inside the K-Rock Centre, still convinced right up to the turnstile that his ticket could not possibly be real. The other was at a racetrack, deliberately not watching.THE PANEL• Shawn from Ottawa - on Hipbase since he was sixteen and the resident kid brother of that community. In the family section on the night. In Kingston two nights later on a ticket a stranger handed him for nothing.• Justin from Bridport - Discovering Downie panelist, and the PR guy, announcer, lawnmower, and toilet cleaner at a Vermont dirt track. The American in the upper bowl who felt Canadian for exactly one night.SOURCESSet list for August 18, 2016 at the Canadian Tire Centre in Ottawa, and the July 22, 2016 Victoria set list - source: setlist.fm. Thanks to Darren at The Tragically Hip Archive, and to the tapers, for the recordings Shawn listened back to before this one.THE GATHERING IN KINGSTONAugust 20 to 23, 2026, alongside Forever Hip - a mixer at the Merchant Pub, Choir! Choir! Choir! in Springer Market Square, a listening party for "The Tragically Hip Live, July 22 - August 20, 2016", a Long Time Running screening, and a farewell brunch at Morrison's. The CBC broadcast re-airs on the 22nd. Email jd@tthpods.com to get on the list. And if you spot a purple shirt or a purple lanyard in Kingston that weekend, that's a safe person to talk to.GEDFEST TORONTOSaturday, October 17, 2026 at the Horseshoe Tavern, with Grace, 2. Raising money for Campfire Circle and the Murphy Family Fund in Precision Medicine in Pancreatic Cancer. Tickets: facebook.com/GEDfestYYZThanks to Shawn and Justin, because without them, there's not a show. Next stop: Kingston, and the end of the line.MORE FROM THE TOURVictoria: https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/99071e40-9d10-48f8-9b5d-f92416e791c3Winnipeg: https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/bf776e9a-c431-41bc-b605-f73fff1155d3And because 'Gus: The Polar Bear from Central Park' turned up in the Ottawa set, The Tragically Hip On Shuffle - Live Stream: Gus: The Polar Bear From Central Park: https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/68d2991b-9074-43ef-bd71-aa832c59a787SUPPORT THE WORKThe tip jar: buymeacoffee.com/tthtop40Web: home.tthpods.com | Facebook: community.tthpods.com | Instagram: @tthpods | YouTube: youtube.com/@tthpods | Newsletter: subscribe.tthpods.com | Email: jd@tthpods.com#TheTragicallyHip #GordDownie #DayForNight #InBetweenEvolution #HipFans #TTHPodsSupport this podcast at — https://redcircle.com/tthtop40/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

August 16, 2016. The Hip arrived in the Hammer, and three fans who were in the building take jD back inside - ten years to the day.Tuesday, August 16, 2016. FirstOntario Centre in Hamilton, four days out from the end of everything, and The Tragically Hip pulled into a city that watched them play to nobody once and never forgot it.Ten years to the day, jD sits down with three fans who were there for that room: Gino from Buffalo, Matt from Buffalo, and John from Mississauga. Two of them had never been on a podcast before in their lives. One of them never made it through the doors.The songs first, because the songs are always first. Gino takes 'Poets', the last one of the main set, the one where Gord stopped and told the room about The Hip's first Hamilton gig - a club, zero people, and an owner who told them nobody gets paid until every song gets sung. So they played another hour to an empty room. Ten years and a lifetime later, Gord looked out at a full arena and, the way Gino heard it, said something close to look at us, look at where we are now. Us, collectively. Hamilton and The Hip.Matt takes 'Scared', and the line it's been a pleasure doing business with you, and the small jump in the video he was shooting - the moment his buddy behind him lost his knees and fell into his back. John takes 'Courage', because of what it took Gord to get in the van at all. A residency somewhere would have been hard enough. He went across the country instead.Then the tickets, and three completely different scrambles. Matt's Buffalo crew split the presale up like a heist - one guy on London, one on each Toronto night, Matt on Hamilton - with orders that whoever got in bought all four. Matt was the only one who got into the queue, and he had four seats about ten minutes in. Gino got shut out in the fifteen minutes it took the show to vanish, then his friend Greg found VIP seats hours later and warned him they'd be expensive. Gino's answer: I don't care. Third row on the floor. If it was within a 500-mile radius, you weren't stopping me.The day itself: a friend on standby in Niagara Falls, U.S., in case one of Matt's four didn't clear the border, a cash-only scalper outside the arena with PDF printouts and a very loose grip on legitimacy, and their buddy Scott laying out most of the money for a pair of those dubious tickets so a friend from Lockport could drive up and slide in during the first song. Gino owns his company, so Gino gave himself the afternoon off, got to Hamilton by mid-afternoon, and ate Portuguese chicken at the Charred Rotisserie House down the road from the barn. We ate like kings. He has been back a few times since.And then there is John, who was downtown at the Toronto Stock Exchange that Tuesday, letting a vendor in to do a routine job. At 2:30 the vendor crashed the system. Eight hours to bring it back. John is standing on a floor you get onto with retina scans and palm prints, he cannot leave the vendor alone, and his company supplies data to the exchange at thousands of dollars an hour. He had a ticket in his pocket and a family carload heading to Hamilton without him. So he stood there and asked himself the only question he had. What would Gord do? What's the Canadian thing to do? He thought about '38 Years Old' - which is the plate on his car - and the father in that song who turns his own son in because it is the right thing. John stayed at his post. He called his sons and told them to give the ticket away. Every August 16th since has been one of the saddest days of his year.Inside the building, the two who made it describe the same night from two heights. The small stage, the band pressed in around each other, a band of brothers making life as easy for Gord as they could. Gord finding faces one at a time, holding them, nodding, gesturing, taking what Gino calls little memory snippets for himself. The monitor on the floor by his feet for the words that wouldn't come. Gino has seen this band more than forty times, and he puts Hamilton at the top for sheer energy. Matt's read is sharper still: the energy was all there, the memory just couldn't always match it.The set list gave Hamilton 'Fifty-Mission Cap', 'Eldorado', and 'At the Hundredth Meridian' early, four from "World Container" as the night's rare record, and the best four of the six "Man Machine Poem" songs that made the tour. 'Poets' to close the main set. 'Gift Shop', 'Don't Wake Daddy', and 'Ahead by a Century' in the first encore. Then 'Fiddler's Green' and 'Twist My Arm' in the second, and a song Gino had never heard live anywhere. Matt has one regret and it is a beer. He went for one during 'Escape Is at Hand for the Travellin' Man', found the concourse narrow and the taps in the basement, and came back up on 'Fireworks' having missed ten minutes he will never get back. So there's that.Gino's detour is worth the price of admission on its own - Highland Bowl in Rochester, a grass amphitheatre, a downpour with thunder and lightning, the band stopping for maybe ten minutes, Gord calling out to the lovers of music who stayed, and grown adults sliding down the wet hill on their bellies toward the stage. Second best night he ever had with this band. Hamilton was first.Then the lights. Gino describes an arena that felt like one family at a memorial service, except it wasn't a somber memorial service - it was everybody holding everybody else up while Gord stood there telling them from the stage that it was going to be okay. Half an hour after the last note the set list was sitting within arm's reach, so Gino took it, and they passed it around for photographs. Nobody wanted to leave. Matt walked over to the King George pub with seven other people and found something else entirely. It almost had the feeling of a wake. Nobody wanted another round. Everybody was thankful. Everybody knew.August 20th finds all three of them in very different rooms. John rigged an aerial in the backyard of his brother's cottage outside Montreal, set both PVRs at home, and asked the local bar in a small French-Canadian town whether they'd be showing it - they had no idea what he was talking about. Don't move that coat hanger outside. Matt spent three hours assembling a children's play kitchen for his two-year-old daughter with the broadcast on, which should have taken one. Gino watched with a dozen guys at a friend's place, where Greg leaned over and said the thing nobody else had thought: doesn't he look nervous? He did. Of course he did.The landing belongs to John, though. There was no goodbye for him that night, so it came slowly, over days and weeks, like a song fading out instead of ending. And it kept going. He has a nine-year-old granddaughter now who knows the words, and he took her to Chudleigh's in Milton to see the Practically Hip so she could dance to them. Another generation, flying the flag.THE PANEL• Gino from Buffalo - forty-plus shows with The Hip, third row on the floor in Hamilton on a VIP ticket his friend Greg found hours after the show sold out, and a plate of Portuguese chicken beforehand he still drives back for. He came home with the set list. He listens to this band every single day.• Matt from Buffalo - second row of section 120, with a photo from that night still hanging behind him on camera. He ran the Buffalo crew's presale plan, got the only four seats any of them landed, filmed 'Scared' through the moment his friend's knees went, and lost ten minutes of the night to a beer line in the basement.• John from Mississauga - the one who didn't get in. A crashed system on the Toronto Stock Exchange floor at 2:30 on show day, a ticket handed off to somebody else, and a decision he made by asking what Gord would do. He watched August 20th through a coat hanger aerial at a cottage. His granddaughter is nine and already knows the words.SOURCESSet list for August 16, 2016 at FirstOntario Centre in Hamilton (now TD Coliseum) - source: setlist.fm.THE GATHERING IN KINGSTONAugust 20 to 23, 2026, alongside Forever Hip - a mixer at the Merchant Pub, Choir! Choir! Choir! in Springer Market Square, a listening party for "The Tragically Hip Live, July 22 - August 20, 2016", a Long Time Running screening, and a farewell brunch at Morrison's. The CBC broadcast re-airs on the 22nd. Email jd@tthpods.com to get on the list. And if you spot a purple shirt or a purple lanyard in Kingston that weekend, that's a safe person to talk to.GEDFEST TORONTOSaturday, October 17, 2026 at the Horseshoe Tavern, with Grace, 2. Raising money for Campfire Circle and the Murphy Family Fund in Precision Medicine in Pancreatic Cancer. Tickets: facebook.com/GEDfestYYZThanks to Gino, Matt, and John, because without them, there's not a show. Next stop: Ottawa.MORE FROM THE TOURWinnipeg: https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/bf776e9a-c431-41bc-b605-f73fff1155d3Calgary Night 2: https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/98943c27-bdae-4f56-84d4-a57754be7719SUPPORT THE WORKThe tip jar: buymeacoffee.com/tthtop40Web: home.tthpods.com | Facebook: community.tthpods.com | Instagram: @tthpods | YouTube: youtube.com/@tthpods | Newsletter: subscribe.tthpods.com | Email: jd@tthpods.com#TheTragicallyHip #GordDownie #WorldContainer #RoadApples #HipFans #TTHPodsSupport this podcast at — https://redcircle.com/tthtop40/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

September 14th, 2009. Edmonton. The last time The Tragically Hip ever played 'Emperor Penguin', and not one person in that building knew it.Seventy-two performances. That's the whole run. The first on July 2nd, 1998, a couple of weeks before "Phantom Power" was even in stores, and the last one in Edmonton on the We Are The Same tour before the song went in a drawer for good. Justin pulled that off setlist.fm live on the stream, Hipbase backs it up, and it turned into the thing nobody saw coming, because one of the two guys at the table tonight is Shawn from Edmonton. He was at that show. He found out on mic.We're on a Thursday this week, which is the end of the Thursday experiment. Back to Wednesdays next week. It was nice while we had it.'Emperor Penguin' landed at number 32 on the TTHTop40 Countdown and neither panelist is at peace with it. One of them would have guessed somewhere around 65. The other would have shoved it higher. Nobody splits the difference. So there's that.Then we spin a live version from Massey Hall, 2009, and Gord introduces the song with a line about why they don't play it often that tells you everything about how the band felt about it. There's a ninety-second outro hanging off the back of it that belongs to Robbie and nobody else. And somewhere early on Gord comes in on the wrong verse and does something with the save that Justin had been chewing on all day before we even hit record.WHAT ELSE IS IN HERE• Two readings of the lyric that come at it from opposite ends and land in the same spot, and one of them hinges on which parent actually sits on the egg.• "I like the tone of your trumpet. Come on, let's spill some paint." The most abstract stretch on the whole record, a notebook theory, and a guess involving Josh Finlayson that may not survive contact with HipMuseum.• The late night call in radio show sitting underneath these lyrics, and the drive home through the Bible Belt that Justin still can't shake loose from this song.• Shawn plays bass, so he hears this as a Paul and Robbie record, with Gord Sinclair and Johnny Fay rock solid and deliberately out of the way. Then Robbie takes it home.• Steve Berlin, the first of his two with the band, and what having a producer in the room at the Bathhouse did to the atmosphere of this thing.• "Phantom Power" as the line in the sand. The last record of the first era, and what happened to a good chunk of the congregation immediately after it.• Shawn spent real time with the guys in the early days. Sound checks with six people in the room. Gord showing him the notebook. And a lyric on one of the most loved songs in the catalogue that he can tell you exactly where they were sitting when it came up. We get about ninety seconds of that story. It deserves its own episode, and we are going to get it.Next week is 'Tiger The Lion', which is track one on the record that follows the record that ends with this song. Brand new panel, brand new song, and yes, the shuffle is actually random. I promise.THE PANEL• Justin from Bridport, Vermont. He announces the sprint cars of New England, so if you're anywhere in the northeast, go find a dirt track. He's also a Discovering Downie panelist.• Shawn from Edmonton. The Port Bickerton Lighthouse Arts Festival goes August 24th in Port Bickerton, Nova Scotia, put on by the Port Bickerton Lighthouse Association. East Coast and Maritime acts, artists, and the biggest one they've done yet.THREE CHAIRS IN THE BATHHOUSEOn August 20th at 1:00 pm I'm filming the final episode of Yer Hipstories: Reflections From The Final Tour inside the Bathhouse in Bath, Ontario. Ten years to the day since Kingston. Three chairs are open to fans. Email jd@tthpods.com by August 15th with your name, email, phone number, whether you can be there in person, and a one minute video on why it should be you. Travel is on you. That's the only catch.THE GATHERING - KINGSTON, AUGUST 20 TO 23Alongside Forever Hip. A mixer at the Merchant Pub, Choir! Choir! Choir! in Springer Market Square, a listening party for "The Tragically Hip Live, July 22 - August 20, 2016", a screening of Long Time Running, the CBC re-airing on the 22nd, and a farewell brunch at Morrison's. Email jd@tthpods.com to get on the list.GEDFEST TORONTO - SATURDAY, OCTOBER 17The Horseshoe Tavern, with Grace, 2. Every dollar goes to Campfire Circle and the Murphy Family Fund in Precision Medicine in Pancreatic Cancer. Tickets through facebook.com/GEDfestYYZ.FIND USHome: home.tthpods.comEmail: jd@tthpods.comFacebook community: community.tthpods.comInstagram: @tthpodsYouTube: youtube.com/@tthpodsYer Letter: subscribe.tthpods.comTip jar: buymeacoffee.com/tthtop40MORE THE TRAGICALLY HIP ON SHUFFLE LIVE STREAM'Bobcaygeon': https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/dca7d1f5-6dea-4df8-b8d1-33008aa46cbd'Gus: The Polar Bear From Central Park': https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/68d2991b-9074-43ef-bd71-aa832c59a787Live performance counts and dates come from Hipbase and setlist.fm, as cited on the stream.#TheTragicallyHip #EmperorPenguin #PhantomPower #TTHPods #HipHeads #OnShuffleSupport this podcast at — https://redcircle.com/tthtop40/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

August 14, 2016. The last night The Tragically Hip ever played Toronto, and three fans who were in the building take jD back inside - ten years to the day.Sunday, August 14, 2016. The Air Canada Centre, the last night of a three-night stand, and the last time The Tragically Hip ever played Toronto. Nobody in the building knew that for certain. Everybody in the building knew it anyway.Ten years to the day, jD steers into uncharted waters (they never do third ones) with three fans who were there: Dave from Thornhill, Jeff from Buffalo, and Jeff from Belleville.The news first, because the news is always first. Jeff from Buffalo came in from a morning run, read the email, and handed his wife the phone because he could not say the words. Dave was getting into his car at Yonge and Eglinton when his whole body sank (and one friend in the group chat skipped the first paragraph and celebrated the new tour - leave it to friends). Jeff from Belleville read it in the front foyer, flashed hot, and told his kids the only thing he could get out: Gord Downie is not doing well.Then the tickets. Jeff from Buffalo broke the algorithm by asking for one seat at a time - it kept offering him another, and two shutouts became four tickets. Dave had Kingston floors on his screen for five full minutes before the error message took them away. Jeff from Belleville stared down the spinning wheel of death for half an hour, then went to plan B. Plan B was this show. So there's that.The day itself: the recording booth outside the ACC that both Jeffs walked past and still regret, a stranger in the beer line who covered the round - "pay it forward, man" - and got the two people behind them too, and Dave breaking his own no-listening-on-show-day rule, blasting The Hip the whole drive down from camp in Haliburton before standing under the marquee, staring at the boys.Then the set list. 'Blow at High Dough' out of the gate, hitting everybody in the face exactly the way it should. 'Opiated', which Dave still can't quite believe he got. Four songs from "Now For Plan A", the rare record of the night. 'The Last of the Unplucked Gems' filling the room while Gord changed - reflection time, Dave calls it. The 'that night in Toronto' line in 'Bobcaygeon' that Gord missed and the whole building carried. And 'Daredevil' into 'Grace, Too' to close - the close-up on the big screen, everything pouring out of him, down to the last bead of sweat.Jeff from Buffalo kept notes from that week, and he read them back. Nervous on the QEW. No crying at the show. And one line that says it all: there's no way he's sick, because nobody sick could be that defiant. The whole evening was a magic spell, and it held right up until the house lights came on. Then it broke.There's a detour into the silver suit (hello, good evening folks, we are the Silver Poets) - armor, magician's misdirection, or just Gord radiating light in a purple hat, depending on which panelist you ask. Jeff from Belleville admits the outfits looked a little cringy in the photos beforehand. Then Gord strutted out. Case closed.And the thread runs where it always runs - to August 20th. A living room outside Buffalo with the kids and Pearl Jam dedications rolling in. The back of the floor at the Danforth Music Hall. And for Dave, a mystery ticket a few weeks later that turned out to be "Secret Path" at Roy Thomson Hall - which he now teaches to his grade 7 and 8 students every January, when it's cold and grey outside and Chanie Wenjack was about their age.The landing belongs to Jeff from Buffalo, though: a compromised man put on a show like that, and the rest of us have our health. We all have something terminal. Live like it.THE PANEL• Dave from Thornhill - a teacher who got one night away from camp in Haliburton and spent it at the last Toronto Hip show, watched Kingston floors dissolve into an error screen, and turned a mystery ticket into "Secret Path" at Roy Thomson Hall. His debut novel, "The Throwback Academy", arrives this October under the pen name TJ Thompson (Instagram: @tjthompsonbooks).• Jeff from Buffalo - four kids (including triplets), a ticket system broken one seat at a time, and notes written in 2016 that he read back on air. He writes feature stories for Buffalo Magazine - the newest one is about washed glass on the Lake Erie shore.• Jeff from Belleville - an hour and forty from home with his wife, Shannon, a plan-B ticket that turned into this episode, and the beer-line story this series will be retelling for a while. His internet fought him all night. He stayed anyway.SOURCESSet list for August 14, 2016 at the Air Canada Centre - source: setlist.fm.SIT IN THE THIRD CHAIRThe finale of Yer Hipstories: Reflections From The Final Tour films inside the Bathhouse in Bath, Ontario on August 20, 2026 at 1:00 pm - ten years to the day since Kingston. There are three fan chairs, and one of them could be yours. Email jd@tthpods.com by August 15 - the day after this episode drops - with your name, email, phone number, whether you can make it to Bath, and a one-minute video on why it should be you. Travel is on you. The chair is on jD.GEDFEST TORONTOSaturday, October 17, 2026 at the Horseshoe Tavern, with Grace, 2. Raising money for Campfire Circle and the Murphy Family Fund in Precision Medicine in Pancreatic Cancer. Tickets: facebook.com/GEDfestYYZTHE GATHERING IN KINGSTONAugust 20 to 23, 2026, alongside Forever Hip - a mixer at the Merchant Pub, Choir! Choir! Choir! in Springer Market Square, a listening party for "The Tragically Hip Live, July 22 - August 20, 2016", a Long Time Running screening, and a farewell brunch at Morrison's. Email jd@tthpods.com to get on the list. And if you spot a purple shirt or a purple lanyard in Kingston that weekend, that's a safe person to talk to.Thanks to Dave, Jeff, and Jeff, because without them, there's not a show. Next stop: Hamilton - the show Dave almost talked himself into.MORE FROM THE TOURVictoria: https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/99071e40-9d10-48f8-9b5d-f92416e791c3Winnipeg: https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/bf776e9a-c431-41bc-b605-f73fff1155d3SUPPORT THE WORKThe tip jar: buymeacoffee.com/tthtop40Web: home.tthpods.com | Facebook: community.tthpods.com | Instagram: @tthpods | YouTube: youtube.com/@tthpods | Newsletter: subscribe.tthpods.com | Email: jd@tthpods.com#TheTragicallyHip #GordDownie #ManMachinePoem #NowForPlanA #UpToHere #TTHPodsSupport this podcast at — https://redcircle.com/tthtop40/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Maria Fundora, Purple Pansies, on Pancreatic Cancer Support, Early Detection, and the Pillars of Hope Gala (North Fulton Business Radio, Episode 978) On this episode of North Fulton Business Radio, host John Ray welcomes back Maria Fundora, owner of Casa Nuova Italian Restaurant in Alpharetta and founder of Purple Pansies. Maria founded the nonprofit in 2008, […]

August 12, 2016. Night two of three at the Air Canada Centre. The rare record is "In Violet Light", and four fans who were in the building take jD back.Friday, August 12, 2016. The Air Canada Centre, night two of three - the middle child of the Toronto stand, the night Patrick calls the forgotten one. Which is a strange thing to call a show Steve ranks, out of the 32 Hip shows he saw, as the best one. Not the biggest. Not the saddest. The best.Ten years to the day, jD sits down with four fans who were in the building - Brian from Buffalo, Steve from Toronto, Patrick from Newmarket, and Katrusia from Hamilton. (He was there too. He'll get into that another time.)Brian opens with something he says he has never told anyone - not on the Hipbase, not even his wife. He heard the rumour about Gord months before the announcement, and spent that winter connecting dots he did not want to connect. Katrusia heard the news on CBC, which felt fitting. Patrick read the email in a newsroom, surrounded by people who suddenly had to cover the story he was living.The ticket tales alone are worth the price of admission (which, for this panel, was face value across the board - a point of pride). A friend in House of Blues accounting. A table in the Air Canada Club. Steve watching night one from the gondola - a bird's eye view of a bird's eye view - and securing his night two seat from a location he is brave enough to name on the record. So there's that.Then the set list. 'Courage' into 'Locked in the Trunk of a Car' into 'Eldorado' to open. 'Membership', the white whale, finally landed for two of the four. 'Throwing Off Glass', live, in 2016. 'What Blue' making its case as the best of the final stretch. 'Grace, Too' carrying more weight than anyone was ready for. And 'Ahead by a Century' to close - a strange choice until it wasn't, with every person in the building on their feet, singing every word.The panel follows the thread to August 20th - two bottles of wine and a laptop in a Buffalo living room, a three-hour detour to stand alone under the Bobcaygeon sign, pizza in residence and pints at the Brass in Kingston - and lands where this series keeps landing. You never regret the shows you see. You regret the ones you miss.(Also, one of these panelists played a living-room concert for a baby who has not arrived yet, and the first song was 'Wheat Kings'. You'll hear it.)THE PANEL• Brian from Buffalo - 54 Hip shows, a "Phantom Power" diehard, and a teacher who crossed the border for this band for years. 'Membership' was the last "Phantom Power" song he had never heard live. Not anymore.• Steve from Toronto - 32 Hip shows, engaged that Canada Day, and proof that "In Violet Light" belongs to Kingston in the summer of 2002. He calls this the best Hip show he ever saw.• Patrick from Newmarket - five of the final six shows, every ticket at face value, a journalist brain that deletes nothing, and a 25-year chase for 'The Luxury' that ended on night one of this stand.• Katrusia from Hamilton - a deadhead family (buy and sell for face only), four shows on this tour, and a 2009 wedding themed to 'That Night in Toronto'. She got 'Bobcaygeon' at this one, standing next to the man she married.SOURCESSet list for August 12, 2016 at the Air Canada Centre - source: setlist.fm.SIT IN THE THIRD CHAIRThe finale of Yer Hipstories: Reflections From The Final Tour films inside the Bathhouse in Bath, Ontario on August 20, 2026 at 1:00 pm - ten years to the day since Kingston. There are three fan chairs, and one of them could be yours. Email jd@tthpods.com by August 15 with your name, email, phone number, whether you can make it to Bath, and a one-minute video on why it should be you. Travel is on you. The chair is on jD.GEDFEST TORONTOSaturday, October 17, 2026 at the Horseshoe Tavern, with Grace, 2. Raising money for Campfire Circle and the Murphy Family Fund in Precision Medicine in Pancreatic Cancer. Tickets: facebook.com/GEDfestYYZTHE GATHERING IN KINGSTONAugust 20 to 23, 2026, alongside Forever Hip - a mixer at the Merchant Pub, Choir! Choir! Choir! in Springer Market Square, a listening party for "The Tragically Hip Live, July 22 - August 20, 2016", a Long Time Running screening, and a farewell brunch at Morrison's. Email jd@tthpods.com to get on the list.Thanks to Brian, Steve, Patrick, and Katrusia, because without them, there's not a show. Next stop: Toronto Night 3 - the night the concourse became a puddle.MORE FROM THE TOURWinnipeg: https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/bf776e9a-c431-41bc-b605-f73fff1155d3Calgary Night 2: https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/98943c27-bdae-4f56-84d4-a57754be7719SUPPORT THE WORKThe tip jar: buymeacoffee.com/tthtop40Web: home.tthpods.com | Facebook: community.tthpods.com | Instagram: @tthpods | YouTube: youtube.com/@tthpods | Newsletter: subscribe.tthpods.com | Email: jd@tthpods.com#TheTragicallyHip #GordDownie #ManMachinePoem #InVioletLight #HipFans #TTHPodsSupport this podcast at — https://redcircle.com/tthtop40/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Tragically Hip Day in Toronto. 'The Luxury' out of the gate, a tour debut in the encore, and a family of four in seats a text message unlocked.DescriptionAugust 10th, 2016. The Air Canada Centre - the first of three Toronto nights on the Man Machine Poem Tour, and the day Ernie from Denville, New Jersey woke up in his hotel room, flipped on the news, and heard the mayor declare it Tragically Hip Day before he had even gotten out of bed. He had flown up alone for his first-ever Canadian show, eleven club nights deep. The city was already celebrating.Then the lights come up and it is 'The Luxury'. Ernie had waited eleven shows to hear it. Jeff from Vaughan, following this band since 1992, can count the times he has heard it live on one hand. Two songs later comes 'Fiddler's Green', and Scott from Huntsville is looking at grown men crying as far as he can see, understanding exactly how the night is going to go. Third song in. They could do whatever they wanted.The roads in are half the story. Everybody got the same email on the Tuesday morning after the May long weekend - the news of Gord Downie's diagnosis, and a tour nobody knew how to feel about. Scott locked down Kingston hotel rooms before tickets even went on sale, then sweated out the Ticketmaster scramble for four Toronto seats - the morning after watching John Mann and Spirit of the West play a fundraiser at the Horseshoe Tavern, two Canadian heartbreaks stacked onto one walk home. Jeff sent a hockey dad four paragraphs about his life following The Hip, hoping to bring his wife and two kids, and got the answer every fan dreams about: they're yours. Which is how, during 'Fifty-Mission Cap', with Bill Barilko's banner up in the rafters, Jeff came to be filming a verse and then swinging the camera around to catch both his kids singing it back.There is a lot of night in here. 'Nautical Disaster' landing in the first encore as a tour debut (confirmed via setlist.fm, and backed by the notebook Ernie filled out that same evening). The crowd carrying the Toronto line in 'Bobcaygeon', the way Scott remembers it. The “Phantom Power” pair that closed the building down. And then the back half of the conversation jumps ahead to August 20th - Scott behind the stage in Kingston, not breathing until the scanner turned his print-off ticket green, Jeff front row in front of Robby Baker for show number 93, and Ernie back in New Jersey with the Kingston broadcast on the big screen and his son beside him.Somewhere in the middle of it, Scott sums up the entire summer in one sentence: “I've never been so excited for something I didn't want to happen.” So there's that.The panelErnie from Denville, New Jersey - eleven Hip shows in clubs from New York City to Syracuse before this one, his first in Canada and his first in an arena, solo in section 313 and never once feeling alone. His daughter has since become one of The Hip's biggest listeners on Apple Music. He also made a horror movie, We Can't Leave, streaming on Amazon Prime (sequel already in the hopper).Scott from Huntsville - travels to Hip shows with his wife and his oldest concert buddy, and hit Toronto Nights 1 and 3 plus Kingston on the final tour, where his kids texted mid-show to check on him. He chairs the Huntsville Festival of the Arts, a year-round festival bringing Canadian acts to Muskoka - huntsvillefestivalofthearts.com.Jeff from Vaughan - following The Hip since 1992, with Kingston set to be show number 93. He did London, multiple Toronto nights, Hamilton, and Kingston on the final run in a custom “Live Between Us” shirt, and brought his wife and both kids to Toronto Night 1. David Bastedo photographed the four of them in their row and sent it to him after the show.Come say hiThe Gathering in Kingston, August 20th to 23rd - a mixer at the Merchant Pub, Choir! Choir! Choir! in Springer Market Square, a listening party for “The Tragically Hip Live, July 22 - August 20, 2016”, a Long Time Running screening, and a farewell brunch at Morrison's. Email jd@tthpods.com to get on the list.GEDfest Toronto - Saturday, October 17th at the Horseshoe Tavern with Grace, 2, raising money for Campfire Circle and the Murphy Family Fund in Precision Medicine in Pancreatic Cancer. Yes, the same room John Mann played the night before the on-sale. That building keeps showing up. Tickets: facebook.com/GEDfestYYZClosingThanks to Ernie, Scott, and Jeff for bringing August 10th back - the flag, the notebook, the kids checking in on their dads. The Tragically Hip play the same building two nights later. Toronto Night 2, August 12th, brand new panel. We go again.More from the seriesVictoria, where the final tour began: redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/99071e40-9d10-48f8-9b5d-f92416e791c3Calgary Night 1, from earlier on the run: redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/2937266e-6c5a-4435-87a8-dcc35b478f37CommunityFacebook community: community.tthpods.comInstagram: @tthpodsYouTube: youtube.com/@tthpodsYer Letter: subscribe.tthpods.comEmail: jd@tthpods.comTip jar (tips, never donations): buymeacoffee.com/tthtop40#TheTragicallyHip #GordDownie #ManMachinePoem #DayForNight #PhantomPower #TTHPodsSupport this podcast at — https://redcircle.com/tthtop40/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Six months into a stage-four pancreatic cancer diagnosis that gave him 90 days to live, Ben Sasse sits down with EconTalk's Russ Roberts for a conversation that refuses easy comfort. The former U.S. senator and University of Florida president is candid about his physical challenges but the heart of this exchange is elsewhere: what actually matters when time is short. Sasse reflects on faith and mortality, the "shattering of idols" like his own workaholism, and his pride in his marriage. Along the way he offers sharp diagnoses of Congress's abdication of responsibility, the crisis inside American universities, and a republic distracted by the "digital casino" in its pocket. Funny, unflinching, and deeply human, it closes with a meditation on raging against the dying of the light while walking with your head bowed.

High-dose Vitamin D fails test in treatment of advanced colon cancer—but can prevent many early cancers from metastasizing; IV Vitamin C may delay progression Myelodysplastic syndrome, pancreatic cancer; Your future drug deliveries may be via drones; How to fight age-related “anabolic resistance”; Can osteoporosis be reversed with hormone replacement therapy and resistance exercise?

Read the full article at: https://oncdata.com/ai-driven-pathological-subtyping-pancreatic-cancer-ashish-manne Artificial intelligence (AI) continues to generate excitement across oncology, but its real-world clinical impact remains inconsistent. In this episode of Exploring AI in Oncology, Dr. Ashish Manne, a Gastrointestinal Medical Oncologist at The Ohio State University Comprehensive Cancer Center, Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, shares his American Association for Cancer Research (AACR) presentation on AI-driven pathological subtyping in pancreatic cancer and highlights the critical shift that is moving AI from theoretical promise to practical application.

Three fans - one in the penalty box, one in the last row, one from down the street - relive the night The Hip said goodbye to London.DescriptionAugust 8th, 2016. Budweiser Gardens, London, Ontario - show nine of the Man Machine Poem Tour, and the last night The Tragically Hip would ever play that city. The lights drop, the band walks out, and the first song is 'Opiated'. Wade had more than 40 Hip shows under his belt and had never heard them open with it. Not once. That kind of night.This one is a full table - three Hipstories from three corners of the map. Dave from St. Louis made the 13-hour drive one week after hernia surgery, found two tickets through a fellow fan on the Facebook forum after a StubHub snafu, called ahead about a wheelchair, and walked out with penalty box seats 15 rows from the stage. Treated, in his words, like royalty. Dan from Buffalo rode in with his brother Matt - the same brother who took him to his first Hip show at the Aud in 1995 - on the way to London, Hamilton, and eventually Kingston. And Wade from London didn't have to travel at all. His city, his buddies up from Leamington, dinner on a patio two blocks from the arena with The Hip on the speakers.The panel walks the whole night. The pause after "I'll die before I quit" in 'It Can't Be Nashville Every Night', and the roar that filled it. "It's been a pleasure doing business with you" landing like a ton of bricks in 'Scared'. 'Pigeon Camera' in the first encore, and Wade suddenly finding dust in the air. The four-songs-per-album architecture of the set, the rarely played "In Between Evolution" material, and the 'Little Bones' that was planned for the night and never came - Gord stepping to the mic instead to thank London and remember the first time The Hip played there, when nine people showed up. Why no 'Little Bones'? The way Dave heard it, it had everything to do with keeping Johnny Fay healthy. So there's that.Then the ride home. A living wake that turned into a celebration, a 12-round boxing match where everybody came out a winner, and two separate no-tickets pacts - one made in London, one in Buffalo - that would carry all three of these guys to Kingston on August 20th. But that's a story the episode tells better.(Setlist details confirmed via setlist.fm - right down to the extended 'Daredevil' outro Dave remembered correctly.)The panelDave from St. Louis - a diehard from the middle of America who has chased The Hip through Chicago, Detroit, and Dallas, and who streamed the Kingston broadcast with friends from his living room on August 20th, 2016.Dan from Buffalo - first show at the Aud in 1995, three stops on the final tour, 28th in line the morning Kingston released 200 tickets, and visible in Long Time Running during 'Courage', singing in the front row of the penalty box.Wade from London - 40 plus shows, from a bouncer-assisted first night at Royal Oak at 17 to Budweiser Gardens, introduced to the band by the cassettes his brother brought home from Western on laundry weekends.Come say hiThe Gathering in Kingston, August 20th to 23rd - a mixer at the Merchant Pub, Choir! Choir! Choir! in Springer Market Square, a listening party for "The Tragically Hip Live, July 22 - August 20, 2016", a Long Time Running screening, and a farewell brunch at Morrison's. Email jd@tthpods.com to get on the list.GEDfest Toronto - Saturday, October 17th at the Horseshoe Tavern with Grace, 2, raising money for Campfire Circle and the Murphy Family Fund in Precision Medicine in Pancreatic Cancer. Tickets: gedfest. caGrace, 2 in London - Friday, August 21st at London Music Hall, playing this very setlist front to back. Wade's plug, and a good one.ClosingThanks to Dave, Dan, and Wade for bringing August 8th back to life - the wheelchair, the pacts, and the dust in the air. The reflections roll on down the 401 next time.More from the seriesVictoria, where the final tour began: redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/99071e40-9d10-48f8-9b5d-f92416e791c3Calgary Night 1, the latest stop: redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/2937266e-6c5a-4435-87a8-dcc35b478f37CommunityFacebook community: community.tthpods.comInstagram: @tthpodsYouTube: youtube.com/@tthpodsYer Letter: subscribe.tthpods.comEmail: jd@tthpods.comTip jar: buymeacoffee.com/tthtop40#TheTragicallyHip #GordDownie #ManMachinePoem #HipFans #TTHPods #CanadianMusicSupport this podcast at — https://redcircle.com/tthtop40/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Joining the Project Purple Podcast from Manchester, Connecticut, pancreatic cancer survivor Michelle Richards and her husband and caregiver Brian share a powerful story of resilience, faith, and facing the unknown together with host Dino Verrelli. Having already navigated cancer many times within their family, including their son's battle with Hodgkin's lymphoma and multiple relatives affected, Michelle describes their diagnosis as “not our first rodeo,” yet one that brought entirely new challenges. After months of persistent symptoms like abdominal pain, fatigue, and discomfort, Michelle shares that she and Brian struggled to find answers, often feeling as though they were “out in the desert” searching for clarity. It wasn't until imaging in late 2024 revealed a tumor that their journey truly began, marked by conflicting diagnoses, emotional highs and lows, and the critical importance of trusting your instincts and advocating for your health. With support from family, including an oncologist niece, and second opinions from leading institutions, Michelle ultimately faced an aggressive pancreatic cancer diagnosis head-on. Throughout treatment, including chemotherapy, radiation, and a major surgery removing much of her pancreas and spleen, Michelle shares how she leaned into positivity, faith, and the belief that mindset plays a crucial role in healing. Brian offers an equally important perspective, reflecting on the caregiver experience and how life is forever changed after a diagnosis like this. From finding meaning in small signs, like rainbows, and placing deep faith in God's plan, to participating in and fundraising for Project Purple's Double Mile just as she finished radiation, Michelle's story is one of determination, community, and hope. Together, Michelle and Brian emphasize the importance of listening to your body, supporting both survivors and caregivers, and choosing strength in the face of uncertainty. Michelle welcomes connection through her Instagram and Facebook pages: https://www.instagram.com/seashell1023 https://www.facebook.com/michelle.s.richards.5/ Subscribe to the Project Purple Podcast for more stories from the pancreatic cancer community. To learn more or donate to Project Purple's mission of a world without pancreatic cancer, visit www.projectpurple.org.

The review ran with no star rating. Infinite stars out of five. Four fans who were inside the MTS Centre explain why that was the only honest math.Episode summaryAugust 5th, 2016. A Friday night, show eight of the Man Machine Poem Tour, and the MTS Centre sits smack in the middle of downtown Winnipeg with no room to breathe. The Tragically Hip open with four straight from "Fully Completely", and the second song is 'Pigeon Camera' - a tour debut nobody in the building saw coming. Ten years on, four fans who were there pass the night around the table with jD.Nicole from Winnipeg raised three daughters on this music and lived her whole life in Thunder Bay before Winnipeg claimed her. She loaded two teenagers into the car and drove eight hours west so her girls could finally see the band she had been singing to them since the car seat. Somewhere in the causeway, the opening notes of 'At the Hundredth Meridian' hit, and the cranky seventeen-year-old looked at her mother and got it.Kim from Cambridge has 41 Hip shows on her card, and Winnipeg came with a bonus night. Same hotel as the band, a waiter's tip to come back to the bar later, a hundred-dollar bar tab worth of nerve, and then a gracious Rob Baker outside the bathroom, a sit-down with Gord Downie's bus driver, and a photo with Gord Sinclair. The guitar picks Bernie Breen handed over are framed with her tour poster.Dave from Montreal got the email on a beach in Crete, day two of a vacation that never recovered. He went to seven shows on the final tour, and this one meant the most - August 5th was the one-year anniversary of his mother's passing. He landed from Calgary on a WestJet flight full of Hip fans, caught the band's tweet about seats beside the stage, and cabbed straight from the airport to the box office. In the hotel lobby he told Paul Langlois that 'Three Pistols' had dodged him for 65 shows. "I can promise you you're going to hear it," Paul said.Alicia from Winnipeg heard the news before almost anybody, because breaking news was her job - she was the editor at Metro Winnipeg. She reviewed the show on deadline, one ticket, scribbling in a row of stunned critics, and filed it with no star rating at all. Infinite stars out of five. You can't score a goodbye.They talk about the four-song "Now for Plan A" block and what it asked of the room. About Gord Downie stopping the show to thank the Winnipeg people who built the band an audience, and a local music writer's phone detonating in real time. About the scream at the end of 'New Orleans Is Sinking' that shut an entire arena up, Kim's Periscope stream that died the moment 'Springtime in Vienna' made holding a phone still impossible, and the moment Dave realized the rants were gone - no workshopping, because there was nothing coming next. And about August 20th, which found them in a second row in Kingston, a basement watch party, and a raucous Thunder Bay bar called The Foundry.Nobody at this table claims the full picture. They just know what that room felt like, and ten years has not dulled it. This is the Winnipeg night, told back by the people who lived it.Key takeaways• 'Pigeon Camera' and 'Streets Ahead' were both tour debuts that night, and the setlist held five songs from "Road Apples" and nothing from "Day for Night" - Calgary got that block two nights earlier (source: setlist.fm).• Kim from Cambridge spent the night before the show in the band's hotel bar. Rob Baker was gracious, a bus driver made the introductions, Gord Sinclair posed for photos, and Bernie Breen handed out guitar picks.• Dave from Montreal traded up to seats beside the stage the day of the show off a band tweet, then put his spare pair on StubHub at face value. He did it again in Hamilton and Ottawa. Ten years later, he is finally telling that secret.• Gord stopped the Winnipeg show to thank the local supporters who built the band an audience there - the panel can only remember it happening one other place, Hamilton. One Winnipeg music writer's phone exploded on the spot.• The night before the show, a Winnipeg lawyer fighting the same brain cancer threw a fundraiser - and the man Nicole from Winnipeg would marry years later was onstage in the band that played it.• Alicia from Winnipeg filed her Metro Winnipeg review as infinite stars out of five, and a Winnipeg Free Press reviewer independently refused to put a number on it too. https://web.archive.org/web/20160807202054/http://www.metronews.ca/news/winnipeg/2016/08/06/review-at-the-hundredth-meridian-tragically-hip.htmlQuotes“I always thought we had more time.”Nicole from Winnipeg“I said, infinite stars out of five, because there's no way to do it, whether you're a Hip fan or not.”Alicia from Winnipeg“When he stepped out in that green suit and just commanded that stage, it ended all of that. All of those nerves that I had before the show, they were gone in the first few notes.”Kim from Cambridge“I just had this moment of heartbreak of, oh, he's not workshopping because there's nothing coming next.”Dave from Montreal“If he saw me, I wanted him to know that Dave from Montreal was staring back at him.”Dave from MontrealGuest information• Nicole from Winnipeg - Thunder Bay born and raised, Winnipeg for the last six years. Raised three daughters on The Hip, and two of them made the 2016 drive with her. Her husband plays in Retro Radio, a Winnipeg classic rock band, and their love story runs through this music.• Kim from Cambridge - 41 Hip shows, Kingston included, second row, in a shirt she made herself. Drove out in a new Jeep with her cousin, camping at Pancake Bay and Sleeping Giant on the way. Keeper of feathers, tour-suit leather patches, and a Six String Nation story.• Dave from Montreal - Montreal journalist. Seven shows on the Man Machine Poem Tour, 65 Hip shows deep by that August. Wrote a pre-tour love letter in the National Post and a Rover essay on cover bands. A book is on the way, and that is all he will say for now.• Alicia from Winnipeg - journalist and then-editor at Metro Winnipeg, who reviewed the show that night. On weekends she fronts Whoopsie Daisy, a Winnipeg classic rock cover band, where 'New Orleans Is Sinking' gets the rage out the healthy way.  https://whoopsiedacey.wordpress.com/Resources, links and references• setlist.fm - the full Winnipeg, August 5 2016 setlist, including both tour debuts.• David Bastedo - The Tragically Hip's official concert photographer. His Winnipeg crowd shot is the one Dave found himself inside.• Dave's pre-tour love letter in the National Post. https://nationalpost.com/entertainment/music/the-tragically-hip-gord-downie• Dave's Rover essay on cover bands, The Strictly Hip, and letting the music live on. https://therover.ca/searching-for-the-tragically-hip/• The bands keeping the music live, named on mic: Killer Whale Tank (Winnipeg), The Incredibly Hip (Brandon), The Hip Experience (on tour across Canada), The Strictly Hip (Buffalo), and Whoopsie Daisy.• "Secret Path" and The Downie Wenjack Fund - the work Nicole's daughter carries forward from the final tour.Calls to actionMeet us in Kingston. The Gathering runs August 20 to 23 - a mixer at the Merchant Pub, Choir! Choir! Choir! in Springer Market Square, a first listen of "The Tragically Hip Live, July 22 - August 20, 2016" the day it drops, a Long Time Running screening, and a farewell brunch at Morrison's on the way out of town. Get on the list. email jd@tthpods.comGEDfest comes to Toronto. October 17th, the anniversary of Gord's passing, at the Horseshoe Tavern with Grace, 2. Nine years running, over $750,000 raised, and this year it is for Campfire Circle and the Murphy Family Fund in Precision Medicine in Pancreatic Cancer. gedfest.caBuy jD a coffee. Editing four loquacious guests is a labour of love. Tips only, no guilt. So there's that. [hyperlink: Buy jD a coffee - buymeacoffee.com/tthtop40Related episodes• Yer Hipstories - Edmonton 2, July 30, 2016 https://kite.link/Edmonton2• Yer Hipstories - Victoria, July 22 2016 https://kite.link/Victoria• Now for Plan A - Redux https://kite.link/nowforplanaClosing paragraphNicole, thank you for the sixteen-hour round trip and for the image of a two-year-old singing 'Boots or Hearts' from a car seat. Kim, thank you for holding your nerve at that hotel bar until it turned into guitar picks. Dave, thank you for bringing your mom into the room with you, and for owning every emotion Gord taught you to own. Alicia, thank you for infinite stars out of five, the only rating system this series recognizes.The band takes an extra day off, then it is Ontario the rest of the way home. Come back on August 8th for London, August 8 2016 - new building, new panel, and the home stretch beginning. If you were in one of these rooms, leave yer Hipstory. This series is stitched together from them.Socials and community• Facebook: facebook.com/groups/tthpods• Instagram: @tthpods]• YouTube: youtube.com/@tthpods]• Email: jd@tthpods.com]#TheTragicallyHip #GordDownie #ManMachinePoem #FullyCompletely #RoadApples #NowForPlanASupport this podcast at — https://redcircle.com/tthtop40/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Join us in this insightful episode of our new series, Partners in Practice. We delved into the critical role of teamwork in cancer care, focusing on the treatment landscape of metastatic pancreatic cancer. In this episode, we were joined by Dr. Timothy Brown, a GI medical oncologist from UT Southwestern, and Ms. Heather Klein, a GI-focused nurse practitioner. Together, we explored the latest treatment options, including modified FOLFIRINOX, NALIRIFOX, gemcitabine with nab-paclitaxel, and the emerging role of novel therapies like RAS inhibitors. Key topics include: Overview of current treatment paradigms for metastatic pancreatic cancer Discussion of side effects and patient management strategies The importance of communication and collaboration within the oncology team Insights into the future of pancreatic cancer treatment and the potential of new therapies Whether you're a healthcare professional, a patient, or simply interested in oncology, this episode offers valuable perspectives on delivering compassionate and effective cancer care.   Listen us on: Spotify: https://open.spotify.com/show/31BXhY9FM4gPWG10WgE11o  Follow us on social media: ⁠X/Twitter: https://x.com/oncbrothers  Instagram: https://www.instagram.com/oncbrothers  Website: https://oncbrothers.com/ Don't forget to like, subscribe, and hit the notification bell for more episodes from the Oncology Brothers! #PancreaticCancer, #PartnersInPractice, #RASinhibitors, #OncologyBrothers

The band took their bow. The house lights came up, and nobody in the Saddledome moved. This is the night the ovation would not stop.Episode summaryAugust 3rd, 2016. A Wednesday. Two nights after the first Calgary show, The Tragically Hip walked back into the Scotiabank Saddledome and played the city goodbye. Ten years on, three fans who were in the building pass the night around the table with jD.Spencer from Calgary is back from the night one episode. This was his third show of the Man Machine Poem Tour and the last time he saw the band live, and he spent it with Alan and Chantel, old friends from ten years of Hitmen games and Saddledome nights. His friend Al's text said it best: heavy but celebratory, like we all knew what was happening but we chose to live in the moment.Julie from Calgary hadn't seen The Hip since 1997. The tickets were a first date anniversary present. She and Keith from Calgary went with her parents, still dating, married the next year, and 'Ahead by a Century' was the wedding song.They talk about the word glioblastoma and where it landed in Julie's family. About Spencer's Periscope vigil in a Calgary bar the night the tour opened in Victoria. About 'Scared' with the lights up, the Jaws shirt, and an ovation that went on so long Gord Downie just stood there in the house lights, telling Calgary it was beautiful.Nobody here claims to be the expert. They were in the room, and ten years later two of them run a charity festival because of it. That part comes up too.Key takeaways• The tickets were a first date anniversary present. Keith and Julie were still dating at the show, married the next year, and 'Ahead by a Century' was their wedding song. Spencer had it at his wedding too.• Spencer watched the Victoria opener through a stranger's Periscope stream in a Calgary bar, and only breathed again once Gord got through the first song.• The middle of the set was an "In Violet Light" collector's run: 'Use It Up' (first since 2006), 'It's a Good Life If You Don't Weaken' (tour debut), 'Throwing Off Glass' (first since 2009), and 'The Dire Wolf' (tour debut). Verified against setlist.fm, cross-referenced with Hipbase.• Julie marks 'Scared' as the moment the night turned - lights up, arms around strangers, the first cracks showing.• The morning the news broke, Keith wore The Hip under his suit to client meetings at the bank, and decided anyone put off by it was not his kind of client anyway.• GEDfest exists because of this show. Julie and Keith founded it after the tour, it turns nine this year, and Spencer signed on as an ambassador before the episode was over.Quotes"Everyone just became one. And for one night, there's very few nights in your life where everybody is connected, positive, happy, loving, sad. You could have hugged anyone in there. You could have kissed anyone in there. It would have been accepted."- Julie from Calgary"This might sound like hyperbole, but in a lot of ways that show changed my life."- Keith from CalgaryGuest information• Spencer from Calgary - back from night one. Three shows on the final tour, and this was the last time he saw The Hip live. His daughter's name is Grace. Draw your own conclusions.• Julie from Calgary - GEDfest co-founder. Had not seen The Hip since 1997. Her first podcast, ever. She did great.• Keith from Calgary - GEDfest co-founder. Still has the paper tickets. The poster is framed on the wall.Resources, links and references• setlist.fm - the full Calgary, August 3 2016 setlist, including both tour debuts and the ten year gap on 'Use It Up'. • Hipbase - primary source for The Tragically Hip setlists and discography, cross-referenced against setlist.fm. • GEDfest - live music for the life and legacy of Gord Edgar Downie, with proceeds to cancer charities across Canada. gedfest.ca]• Helping Families Handle Cancer - the Calgary charity Spencer's sister runs for families whose child is going through cancer.• Lilliput Hats - Karyn Ruiz's Toronto shop, where the hats Keith remembers came from. Related past episodes:• Yer Hipstories: Reflections From The Final Tour - Vancover Night 1 https://kite.link/Vancouver1. • Yer Hipstories: Reflections From The Final Tour - Victoria, July 22 2016 - the opening night Spencer watched through a stranger's phone. https://kite.link/Victoria• Fully & Completely: redux - Man Machine Poem - the record behind the four song block.https://kite.link/MMPreduxThings to knowGive the anniversary somewhere to go. GEDfest plays Toronto for the first time - Saturday, October 17th, the anniversary of Gord's passing, at the Horseshoe Tavern with Grace, 2. Every dollar raised goes to Campfire Circle and the Murphy Family Fund in Precision Medicine in Pancreatic Cancer. Julie and Keith built this festival out of the night you just heard about. Tickets are on sale now. So there's that. [hyperlink: Grab tickets - GEDfest.caCome home to Kingston. The Gathering runs August 20th to 23rd - a mixer at the Merchant Pub, Choir! Choir! Choir! in Springer Market Square, a listening party, a Long Time Running screening, and a farewell brunch at Morrison's. If you're making the trip, get on the list. [hyperlink: Email jd@tthpods.com]Buy jD a coffeeEditing is hard. Help keep the battery charged and buy jD a coffee. Tips only, no guilt. [hyperlink: Buy jD a coffee - buymeacoffee.com/tthtop40Closing paragraphJulie, thank you for doing your first podcast ever and for the bubble of love. Keith, thank you for the postcard: the whole dome on its feet, lights up, nobody leaving. Spencer, thank you for coming back, and for signing up as a GEDfest ambassador live on mic. That is how this community works. In a couple of days the tour crosses the Rockies - Winnipeg, August 5 2016, with a brand new panel. The Tragically Hip Podcast Series keeps heading east, all the way home.Socials and community• Facebook: facebook.com/groups/tthpods• Instagram: @tthpods• YouTube: youtube.com/@tthpods• Email: jd@tthpods.com#TheTragicallyHip #GordDownie #GordonEdgarDownie #ManMachinePoem #InVioletLight #HipFansSupport this podcast at — https://redcircle.com/tthtop40/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

This week, Bobbi Conner talks with MUSC Dr. William Hawkins about recent advances in pancreatic cancer treatment.

What is in the This Week in Science Podcast? This Week: Interview W/Dannielle Engle, PhD, Pancreatic Cancer, Gut Memories, Memorable Brain Changes, and Much More Science to Dish About! Become a Patron! Check out the full unedited episode of our podcast on YouTube or Twitch. And remember that you can find TWIS in all the […] The post 29 July, 2026 – Episode 1069 – The Dish on Disease-in-a-Dish appeared first on This Week in Science - The Kickass Science Podcast.

Joining the Project Purple Podcast from Brooklyn, Keith De-Lin takes listeners on a journey from a misdiagnosis to discovering a rare neuroendocrine pancreatic tumor with host Dino Verrelli. A lifelong vegan and dedicated fitness enthusiast, Keith was always focused on his health, but at 48, persistent acid reflux and unusual symptoms led him to push for answers that would change his life. Initially diagnosed with pancreatic adenocarcinoma, Keith underwent months of intensive chemotherapy intended for that diagnosis, as well as treatment for a severe portal vein thrombosis, before finally receiving the correct diagnosis: non-functioning neuroendocrine pancreatic cancer. He reflects on the emotional rollercoaster of facing a misdiagnosis, the vital role of advocacy—especially having his doctor wife by his side—and how his mindset and positivity carried him through treatment. Keith shares how living in the moment, relying on a strong support system, and embracing your unique recovery journey can guide you through even the most challenging experiences. From maintaining his workout routine to planning adventures like climbing Mt. Kilimanjaro, he demonstrates resilience, hope, and perspective in action. Keith welcomes connection through his Instagram @keithdelin: https://www.instagram.com/keithdelin/ Subscribe to the Project Purple Podcast for more stories from the pancreatic cancer community. To learn more or donate to Project Purple's mission of a world without pancreatic cancer, visit www.projectpurple.org.

In this episode, Dr Paul E. Oberstein, Dr Andrew H. Ko, and Dr Efrat Dotan discuss recent advances in pancreatic cancer, including: The evolving role of chemotherapy Utility of tumor treating fields for the treatment of locally advanced pancreatic adenocarcinoma Emerging RAS-targeted strategies and novel approaches for CLDN18.2- and MTAP-altered disease The potential impact of these developments on future treatment sequencing and supportive care  Get access to all of our new podcasts by subscribing to the Decera Clinical Education Podcast on Apple Podcasts, YouTube Music, or Spotify. Presenters: Paul E. Oberstein, MD, MS Section Chief, GI Oncology Associate Professor of Medicine Co-Director, KRAS Excellence Initiative Perlmutter Cancer Center NYU Langone Health New York, New York Andrew H. Ko, MD, FASCO Professor of Medicine and Associate Chief Division of Hematology/Oncology University of California San Francisco San Francisco, California Efrat Dotan, MD, MTR Clinical Professor of Medicine (Hematology/Oncology) Executive Medical Director, Penn Medicine, Ann B. Barshinger Cancer Center Penn Center for Cancer Care Innovation, Abramson Cancer Center University of Pennsylvania Philadelphia, Pennsylvania Link to full program: https://bit.ly/44HPR1U Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/JPE865. CME/NCPD/AAPA/IPCE credit will be available until July 13, 2027.Restructuring Clinical Care Models in Pancreatic Cancer: Expert Guidance on Improving Patient Outcomes With Modern Therapeutic Strategies in Community Settings In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Revolution Medicines.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/JPE865. CME/NCPD/AAPA/IPCE credit will be available until July 13, 2027.Restructuring Clinical Care Models in Pancreatic Cancer: Expert Guidance on Improving Patient Outcomes With Modern Therapeutic Strategies in Community Settings In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Revolution Medicines.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/JPE865. CME/NCPD/AAPA/IPCE credit will be available until July 13, 2027.Restructuring Clinical Care Models in Pancreatic Cancer: Expert Guidance on Improving Patient Outcomes With Modern Therapeutic Strategies in Community Settings In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Revolution Medicines.Disclosure information is available at the beginning of the video presentation.

Dr. Eric Winer and Dr. Mandar Muzumdar discuss the rise in cases of pancreatic cancer and the study of how the consumption of different types of fats could have an impact on that trend. Yale Cancer Center Visit: https://medicine.yale.edu/cancer/ Email: canceranswers@yale.edu Call: 203-785-4095

Pancreatic cancer has long been considered a death sentence. But a revolutionary new treatment has been shown to double survival times. *** Thank you for listening. Help power On Point by making a donation here: wbur.org/giveonpoint

Clinical trial support companies are rapidly adopting AI, but sponsors have been more hesitant. Raj Indupuri, CEO of eClinical Solutions, gives the top three reasons behind the holdup in AI agent deployment. He explains the specific pattern of uptake for these agents, the required human-in-the-loop oversight, and how the agents can improve clinical trial velocity. Host Deborah Borfitz also gives the latest news on a highly acclaimed treatment for pancreatic cancer, filling evidence gaps in drug safety during pregnancy, guidelines for routinely collected health data for research purposes, an innovative portal aiding bidirectional communication with patients, and more. Show Notes News Roundup KRAS inhibitor therapy for pancreatic cancer Study in The New England Journal of Medicine  News on the Fred Hutch Cancer Center website  Target trial emulation in rural areas Perspective in the Medical Journal of Australia News on the Griffith University website   AI for improving drug safety during pregnancy Report from the Journal of Medical Internet Research Guidelines on the use of routinely collected data Article in The BMJ New regulatory framework in the U.K. Press release by the Medicines and Healthcare products Regulatory Agency  Participant Engagement Portal Article in JNCI Cancer Spectrum Press release from the Alliance for Clinical Trials in Oncology The Scope of Things podcast explores clinical research and its possibilities, promise, and pitfalls. Clinical Research News senior writer, Deborah Borfitz, welcomes guests who are visionaries closest to the topics, but who can still see past their piece of the puzzle. Focusing on game-changing trends and out-of-the-box operational approaches in the clinical research field, the Scope of Things podcast is your no-nonsense, insider's look at clinical research today.  

Dr. Eric Winer and Dr. Pamela Kunz talk about recent discoveries in treating pancreatic cancer which has been resistant to much detection and treatment. Yale Cancer Center Visit: https://medicine.yale.edu/cancer/ Email: canceranswers@yale.edu Call 203-785-4095

Our panel of medical experts discusses the month's biggest healthcare news from a rise in vaccine-preventable illnesses to an increase in alcohol consumption by pregnant women.

Kira Andersen's life took a drastic turn when her husband, Kyle, was diagnosed with stage four pancreatic cancer shortly after the birth of their third child. Refusing to accept a grim prognosis, Kira leveraged her background in medical and pharmaceutical sales to advocate for experimental treatments, securing "compassionate use" for a promising inhibitor. This intervention, now known as the "Kyle Anderson Regimen," granted their family an extra year of life together and is now saving other stage four patients. Today, Kira honors his memory by hosting the "Yes We Can" podcast and continuing a relentless mission to raise the final $1 million of a $3 million goal for targeted research at Siteman Cancer Center.

In this episode, we review the high-yield topic of ⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Pancreatic Cancer⁠⁠⁠⁠⁠⁠ from the Oncology section at ⁠⁠⁠⁠Medbullets.com⁠⁠⁠⁠⁠⁠Follow⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Medbullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbulletsLinkedin: https://www.linkedin.com/company/medbullets

Pancreatic cancer is among the most deadly forms of cancer, and it can be difficult to catch early. But there's some good news: Clinical trials of a new drug called daraxonrasib found that it doubled the survival time of patients with advanced pancreatic cancer. And some oncologists are calling it a game changer—not just for pancreatic cancer, but potentially other forms of cancer too. Ira talks with oncologist Zev Wainberg, who led a clinical trial for the drug.  Plus, ALS is a degenerative disease that causes patients to lose their ability to walk, swallow and eventually to breathe. Now, there's a drug for a rare genetic form of ALS that can slow the progression or even reverse some of these symptoms. Ira talks with New York Times health and science reporter Pam Belluck about this new treatment. Guests: Dr. Zev Wainberg is a co-director of UCLA Health's GI Oncology Program. Pam Belluck is a health and science reporter for The New York Times. Other episodes you may enjoy: mRNA Vaccine For Pancreatic Cancer Continues To Show Promise How do clinical trials work, and who can participate? Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

We're dropping this bonus episode because something genuinely historic happened in oncology and we couldn't wait until our regular schedule to talk about it. Dr. Mark Lewis, GI medical oncologist, pancreatic cancer survivor, and one of our absolute favorite guests. He just got back from ASCO, the Super Bowl of oncology, where a new drug called daraxonrasib received one of only about six standing ovations in the conference's history, including applause that broke out mid-sentence when researchers showed the survival data on-screen. The drug targets a mutation that drives the vast majority of pancreatic cancer and has been considered "undruggable" for decades and it works not by attacking the mutation directly, but by cutting off the downstream signals it sends, like snipping the wire instead of fighting with the switch. The results are remarkable. In patients who had already received standard chemotherapy, daraxonrasib roughly doubled survival time and delivered it in pill form rather than an IV every two weeks, a meaningful quality-of-life difference for people who are already facing the hardest year of their lives. Mark walks us through the science, the side effects (rash, because RAS proteins live in skin too), the path to FDA approval, and what this means beyond pancreatic cancer, the same KRAS mutations show up in about 30% of lung cancers and 40% of colon cancers. Takeaways: Pancreatic cancer has been devastatingly hard to treat, 85% of patients are incurable at diagnosis because it spreads silently and there's no good screening, leaving most patients with a median survival of about a year on IV chemotherapy. KRAS, the mutation driving nearly all pancreatic cancer, was long considered "undruggable", the protein was so smooth and spherical that no drug could bind to it, and researchers were actively discouraged from pursuing it as a target. Daraxonrasib works by cutting the power rather than fighting the switch, instead of binding to the KRAS protein itself, it uses molecular glue to interrupt the downstream growth signals the mutation sends, an approach that took decades to develop and wasn't taken seriously until now. The trial results roughly doubled survival and the treatment is a daily pill, not an IV, patients who had already been treated with chemotherapy gained approximately an additional year of life with improved quality of life, which represents one of the most significant advances in pancreatic cancer treatment in decades. This breakthrough has implications far beyond the pancreas, KRAS mutations drive about 30% of lung cancers and 40% of colon cancers too, and proving the target is druggable opens the door to a new generation of treatments across multiple cancer types. Want more Dr. Mark Lewis? X: @marklewismd To Get Tickets to Wife & Death: You can visit Glaucomflecken.com/live  We want to hear YOUR stories (and medical puns)! Shoot us an email and say hi! knockknockhi@human-content.com Can't get enough of us? Shucks. You can support the show on Patreon for early episode access, exclusive bonus shows, livestream hangouts, and much more! –⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ http://www.patreon.com/glaucomflecken⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  Also, be sure to check out the newsletter: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://glaucomflecken.com/glauc-to-me/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ If you are interested in buying a book from one of our guests, check them all out here: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.amazon.com/shop/dr.glaucomflecken⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ If you want more information on models I use: Anatomy Warehouse provides for the best, crafting custom anatomical products, medical simulation kits and presentation models that create a lasting educational impact.  For more information go to Anatomy Warehouse DOT com. Link: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://anatomywarehouse.com/?aff=14⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Plus for 15% off use code: Glaucomflecken15 -- A friendly reminder from the G's and Tarsus: If you want to learn more about Demodex Blepharitis, making an appointment with your eye doctor for an eyelid exam can help you know for sure. Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://www.EyelidCheck.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for more information.  Produced by⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Human Content⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

Pancreatic Cancer Halted by Virus Injection Researchers injected an engineered virus directly into pancreatic tumors in three patients — the virus replicated inside malignant cells, triggered an immune response, and stopped tumor growth and spread at an intentionally low early dose. Host Dave Asprey breaks down why oncolytic viruses can do what chemotherapy can't, how the tumor's dense biological wall becomes less of an advantage when a virus can replicate inside it directly, and why a measurable response at a safety dose is the kind of early signal that changes how he's watching this field. Sources: https://www.newscientist.com AI Chatbots and Teen Mental Health A new survey shows roughly one in five adolescents and young adults are now going to AI chatbots when they feel sad, anxious, nervous, or stressed, with usage heaviest in the 18–21 range. Host Dave Asprey explains why general-purpose language models designed to be engaging are dangerous as a substitute for real mental health support, why false reassurance from a chatbot may make the pipeline to real care harder to reach, and why this is a health systems story masquerading as a tech adoption story — and what parents need to do about it. Sources: https://www.nbcnews.com GLP-1 Drugs Cut Breast Cancer Risk Penn Medicine published a retrospective analysis of over 111,000 women finding GLP-1 exposure associated with about 35% lower odds of breast cancer in the full cohort and around 30% lower in a matched comparison group. Host Dave Asprey breaks down why this isn't just a weight loss story — it's a metabolic dysfunction story — explains the insulin resistance, inflammation, and hormonal environment mechanisms that may be driving the signal, and makes the case that this finding should be reshaping how oncologists and OBGYNs think about high-risk patients right now. Sources: https://www.pennmedicine.org Putin's $26 Billion Longevity Program The Wall Street Journal reports that Russia has made anti-aging research a Kremlin-level national priority through a $26 billion program including gene therapy, organ bioprinting, and xenotransplantation, led by Putin's daughter Maria Vorontsova and physicist Mikhail Kovalchuk. Host Dave Asprey breaks down what's geopolitical theater, what's legitimately frontier science, and why the real question is whether any findings will make it out to the broader research community or get locked inside a state program. Sources: https://www.wsj.com https://www.france24.com Sauna vs. Cold Plunge A landmark Finnish study tracked over 2,300 men for nearly 21 years and found increasing sauna frequency associated with dramatically lower cardiovascular and all-cause mortality — strongest at four or more sessions per week. Host Dave Asprey settles the debate with the actual data, explains what heat shock proteins and cold shock proteins actually are and why the evidence base behind them is nowhere near equivalent, and calls out the wellness marketing presenting early-stage mouse model research as the cold water equivalent of two decades of human mortality outcomes. Sources: https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2521522 This episode is designed for biohackers, longevity seekers, and high-performance listeners who want mechanism-level clarity on cancer treatment breakthroughs, adolescent mental health and AI, metabolic drivers of disease, geopolitical longevity science, and the real evidence behind popular recovery modalities. Host Dave Asprey connects emerging clinical research, objective epidemiological data, and real-world optimization protocols into actionable frameworks for extending healthspan, sharpening performance, and staying ahead of the science. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: oncolytic virus pancreatic cancer, engineered virus tumor treatment, AI chatbot teen mental health, adolescent AI emotional support, GLP-1 breast cancer risk, semaglutide cancer prevention, metabolic dysfunction root cause disease, Putin longevity program Russia, New Health Preservation Technologies, anti-aging biotech geopolitics, sauna longevity mortality data, cold plunge cold shock proteins, RBM3 heat shock proteins, sauna vs cold plunge evidence, biohacking news 2026, longevity research, Dave Asprey, The Human Upgrade Thank you to our sponsors! - Suppgrade Labs | Grab your DAKE and Minerals 101 duo at shopsuppgradelabs.com and use code DAVEPOD for 15% off today - Essentia | Go to https://myessentia.com/dave and use code DAVE for $100 off The Dave Asprey Upgrade. - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE Resources: • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Intro 00:42 – Pancreatic Cancer Halted by Virus Injection 01:44 – Teens & AI Therapy Chatbots 03:13 – GLP-1 Drugs Cut Breast Cancer Risk 04:30 – Russia's $26B Longevity Program 06:18 – Sauna vs. Cold Plunge 09:10 – Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Headlines: – Welcome to Mo News + Taylor Swift ‘Toy Story' Single (02:00) – Florida Sues OpenAI and Sam Altman Over AI Risks For Kids (04:30) – Claude Maker Anthropic Files For IPO, Setting Up Public-Market Test Of AI Boom (08:20) – US Bombs Iranian Military Sites,Then Downs Missiles Tehran Fired At Troops In Kuwait (12:00) – Iran Warns Israeli Attacks In Lebanon Threaten Ceasefire With US; Trump Says “Shooting Will Stop” (18:00) – Why The Trump Administration Plans To Drop Its "Weaponization" Fund (20:45) – Pancreatic Cancer 'Miracle' Drug Daraxonrasib Doubles Survival Rate In New Trial (25:00) – Scott Pelley Accuses CBS News Boss of ‘Murdering' ‘60 Minutes' (28:30) – Judge Rules Charlie Kirk Suspect's Hearing Will Be Open To The Public (38:00) – Serena Williams Returns to Pro Tennis After Four-Year Hiatus (40:10) – On This Day In History (45:00) Thanks To Our Sponsors: – Monarch - 50% off your first year | Code: MONEWS – Factor - 50% off your first box | Code: monews50off –⁠ Industrious⁠ - Coworking office. 50% off day pass | Code: MONEWS50 – LMNT | Free Sample Pack with any LMNT drink mix or 12oz cans purchase

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Join us as we review recent articles and news featured in The DIGEST, including updated lipid guidelines, GLP1 agonists holds and procedures, the newest drug in pancreatic cancer, and discontinuing thyroid supplementation. Fill your brain hole with a delicious stack of hotcakes! Featuring Drs. Nora Taranto (@norataranto), Laura Glick (@lauraglick) and Matt Watto (@doctorwatto).Claim free CME for this episode at curbsiders.vcuhealth.org!Episodes | Subscribe | Spotify | Swag! |Mailing List | Contact | CME!Credits Written and Hosted by: Nora Taranto MD MSCE, Laura Glick MD,  Matthew Watto MD, FACP Cover Art:  Nora Taranto MD MSCE Reviewers: Emi Okamoto MD  Technical Production: Pod Paste Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP Show Segments Intro and pun   Lipid Management Guidelines Overview  Emerging Treatments in Oncology  Press Release on a new KRAS Inhibitor for Pancreatic Cancer  Perioperative Considerations for GLP-1 Use  Deprescribing Levothyroxine in Older Adults Sponsor: Panacea FinancialIf you're about to make the leap into  residency and feeling the financial pressure of that transition, visit  PanaceaFinancial.com/curbsiders today. Sponsor: UpToDatefor a limited time, get 10% off UpToDate packages with code CURB10. Visit store.uptodate.com to save on your annual or longer personal UpToDate subscription today.