Circulation on the Run

Each week, join Editor-in-Chief Brad Maron, along with cohosts Mercedes Carnethon and Jane Wilcox for the new iteration of Circulation on the Run. This week, join Mercedes and Brad as Fatima Rodriguez joins the podcast for a discussion on the recently released CKM Guidelines. Then, Mercedes welcomes Deputy Editor Tiffany Powell-Wiley as they discuss the Clinician's Corner article type and what prospective authors should consider when submitting a manuscript for this article type. For the episode transcript, visit:  https://www.ahajournals.org/do/10.1161/podcast.20260727.885623

Each week, join Editor-in-Chief Brad Maron, along with cohosts Mercedes Carnethon and Jane Wilcox for the new iteration of Circulation on the Run. This week, join Brad on location at BCVS Scientific Sessions in Boston as he sits down with the new BCVS Council Chair, Sean Wu. Brad and Sean discuss the priorities for BCVS, the standards for high-quality and actionable science in the era of multi-omics, how cardiovascular science can adapt to growing emphasis on acquired determinants of disease, and finally, find ways to improve the clinical translational relevance of basic science. For the episode transcript, visit:  https://www.ahajournals.org/do/10.1161/podcast.20260717.271223

On this week's episode of Circulation on the Run, join Editor-in-Chief Bradley Maron and Deputy Editor Mercedes Carnethon as they welcome Circulation's Executive Editor, Karen E. Joynt Maddox.  Karen discussed health services and health care policy, and what prospective authors should consider when submitting manuscripts to Circulation. Then, Brad and Mercedes welcome authors Marc Humbert and Jason Weatherald as they discuss their review article regarding pulmonary arterial hypertension in the July 14th issue of Circulation. For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20260713.392409

Circulation on the Run welcomes Circulation's new Editor-in-Chief, Bradley A. Maron, MD. Join Brad Maron, along with cohosts Mercedes Carnethon and Jane Wilcox for the new iteration of Circulation on the Run. This week join Brad, Mercedes and Jane as they first welcome Vice Chair Pamela B. Morris as she discusses the 2026 ACC/AHA/AACVPR/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Dyslipidemia. Then join author Hertzel Gerstein as he discusses his article "Cardiovascular Risk Reduction with GLP-1 RA Drugs." Besides gaining insight about leading science research, learn more about the scientific researchers in Circulation on the Run's newest feature, "Get to Know Our Guests." Don't miss this newly revamped podcast! For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20260706.284480

This week marks the final Circulation on the Run under Dr. Joseph Hill's tenure. For this episode, please join our current hosts along with former host Carolyn Lam, Executive Editor James de Lemos, and Editor-in-Chief Joseph Hill as they remember the legacy of the podcast started a decade ago, the important scientific research discussed, and fond memories after 520 episodes. For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20260629.459176

This week, join Circulation's Disparities Editors Mercedes Carnethon, Karol Watson, and Guest Editor Eric J. Brandt as they host this week's Circulation on the Run episode. First, they speak with authors Rishi K. Wadhera and Prihatha R. Narasimmaraj as they discuss their article "The Cardiovascular Cost of Medicaid Cuts Under H.R. 1." Then Mercedes speaks with author Yi-Yun "Crystal" Chen as she discusses her original research article "Multidimensional Social Adversity and Mortality in People With HIV and Heart Failure: Insights From NYC Health + Hospitals HIV–Heart Failure Cohort." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20260615.699938

This week, please join authors Rasha K. Al-Lamee and Fiyyaz Ahmed-Jushuf as well as Associate Editor Emmanouil Brilakis as they discuss the article "Determining the Physiological Threshold for Angina (ORBITA-FIRE): A Double-Blind, Randomized, Placebo-Controlled Study." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20260608.559074

This week, please join author Sreekanth Vemulapalli as he discusses the article "Adaptive AI for Cardiovascular Event Adjudication: Cardiovascular Event Adjudication Across Different Definitions in the ODYSSEY OUTCOMES and EUCLID Trials." For the episode transcript, visit:  https://www.ahajournals.org/do/10.1161/podcast.20260601.995930

This week, please join author Harmony R. Reynolds and Associate Editor Nicholas Mills as they discuss the article " Multimodality Imaging to Determine Underlying Causes of Myocardial Infarction With Nonobstructive Coronary Arteries in Women and Men." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20260526.732262

This week, please join author Nicholas A. Marston and Section Editor Parag Joshi as they discuss the article "Effect of APOC3 Inhibition With Olezarsen on Coronary Atherosclerosis: Essence-TIMI 73b Imaging Study." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20260518.156242

This week, please join author Jean-Luc Vachiery and Associate Editor Kelly Chin as they discuss the article "Sotatercept for Combined Post- and Precapillary Pulmonary Hypertension Associated With Heart Failure: Results From the Phase 2, Randomized, Placebo-controlled CADENCE Study." For the episode transcript, visit:  https://www.ahajournals.org/do/10.1161/podcast.20260511.411136

This week, please join authors Gregory D. Lewis and Ravi V. Shah as they discuss the article "Multiorgan Physiologic Deficits During Exercise Identify Clinical and Molecular Predisposition to Heart Failure With Preserved Ejection Fraction." For the episode transcript, visit:  https://www.ahajournals.org/do/10.1161/podcast.20260504.789757

This week, please join Chair Roger Blumenthal and author Gregg Fonarow as they discuss the recently published "2026 ACC/AHA/AACVPR/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Dyslipidemia" along with an accompanying commentary "The 2026 American College of Cardiology/American Heart Association Multisociety Guideline on the Management of Dyslipidemia: A More Precise—But More Complicated—Framework for Atherosclerotic Cardiovascular Disease Prevention and Treatment." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20260427.104601

This week, please join author Alexander "Sasha" Opotowsky as he discusses the article "The Fontan Outcomes Network: Findings After 2 Years and 1121 Participants." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20260420.342132

This week, please join author Edouard L. Fu and Associate Editor Dhruv Kazi as they discuss the article "Risk of Heart Failure Hospitalization for GLP-1 Receptor Agonists Versus DPP-4 Inhibitors or SGLT-2 Inhibitors in Patients With Type 2 Diabetes: A Target Trial Emulation." For the episode transcript, visit:  https://www.ahajournals.org/do/10.1161/podcast.20260413.101706

This week, please join author Rik Pauwels as he discusses the article "Wearable-Derived Training Load and Coronary Atherosclerosis in Middle-Aged and Older Athletes and Physically Active Controls: A New Perspective From the Master@Heart Study." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20260406.965700

This week, please join authors Charles Khouri and Clément Jambon-Barbara as well as Associate Editor Kelly Chin as they discuss the article "Second- and Third-Generation BCR-ABL Tyrosine Kinase Inhibitors and the Risk of Pulmonary Arterial Hypertension: A Prevalent New-User Design." For the episode transcript, visit:  https://www.ahajournals.org/do/10.1161/podcast.20260330.77255

This week, please join author Ivo Roca-Luque and Editorialist Andrew Arai as they discuss the article "PAM-VT 2 Study: Long-Term Scar Evolution and Ablation Lesion Assessment by Late Gadolinium Enhancement Cardiac Magnetic Resonance After Ventricular Tachycardia Ablation" and the accompanying editorial " Cardiac Magnetic Resonance Before Ventricular Tachycardia Ablation and During Follow-Up." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20260323.157498

This week, please join author Niklas Dyrby Johansen and Associate Editor Sandeep Das as they discuss the article "High-Dose Versus Standard-Dose Influenza Vaccine and Cardiovascular Outcomes in Older Adults: The FLUNITY-HD Prespecified Pooled Analysis." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20260316.180799

This week, please join author Michael J. Blaha as he discusses his article "Prospective Associations of Obesity and Obesity Severity With 9 Cardiovascular Outcomes: The Cross Cohort Collaboration." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20260309.22779

This week, join author Enrico Ammirati and Associate Editor Justin Ezekowitz as they discuss their article "Natural History of Patients With Histologically Proven Acute Eosinophilic Myocarditis." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20260302.497755

This week, join author Moritz J. Hundertmark and Associate Editor Vlad Zaha as they discuss their article "IMPROVE-DiCE, a 2-Part, Open-Label, Phase 2a Trial Evaluating the Safety and Effectiveness of Ninerafaxstat in Patients With Cardiometabolic Syndromes." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20260223.163027

This week, please join guest hosts Sana Al-Khatib and Mercedes Carnethon as first, they briefly introduce Circulation's annual Go Red for Women® issue. Then, our hosts welcome author Emilia Benjamin and Section Editor Maryjane Farr as they discuss the unique challenges women cardiologists have faced in the past and still encounter, and the importance of mentors and mentees in the field of cardiology. Finally, our hosts welcome Ju-Young (Judy) Shin to discuss her article "Association of Statin Discontinuation in Pregnancy With Maternal Cardiovascular Health and Birth Outcomes: A Nationwide Cohort Study." Don't miss this important podcast! For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20260213.424527

This week, join authors Shaan Khurshid and Julian S. Haimovich as they discuss their article "Incidence, Risk Factors, and Outcomes in Stressor-Associated Atrial Fibrillation: Insights From the VITAL-AF Trial." For the episode transcript, visit:  https://www.ahajournals.org/do/10.1161/podcast.20260209.180892

This week, join author Chao Jiang as he discusses the article "Dapagliflozin to Reduce Early Recurrence After Catheter Ablation for Atrial Fibrillation: The DARE-AF Randomized Clinical Trial." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20260202.172048

This week, join authors Xiangbin Pan and Jie Dong, as well as Associate Editor Dharam Kumbhani as they discuss the article "Transcatheter Closure of Patent Foramen Ovale with a Novel Biodegradable Device: A Prospective, Multicenter, Randomized Controlled Clinical Trial." For the episode transcript, please visit: https://www.ahajournals.org/do/10.1161/podcast.20260112.347892

This week, please join author Mathew S. Maurer as he discusses the article "Coramitug, a Humanized Monoclonal Antibody for the Treatment of Transthyretin Amyloid Cardiomyopathy: A Phase 2, Randomized, Multicenter, Double-Blind, Placebo-Controlled Trial." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20260126.13097

This week, join author Albert Ariza-Solé and Associate Editor Parag Joshi as they discuss the article "Triple versus Dual Lipid Lowering Therapy in Acute Coronary Syndrome: The ES-BempedACS Randomized Clinical Trial." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20260120.624282

This week, join authors Xiangbin Pan and Jie Dong, as well as Associate Editor Dharam Kumbhani as they discuss the article "Transcatheter Closure of Patent Foramen Ovale with a Novel Biodegradable Device: A Prospective, Multicenter, Randomized Controlled Clinical Trial." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20260112.347892

This week, join authors Xiangbin Pan and Jie Dong, as well as Associate Editor Dharam Kumbhani as they discuss the article "Transcatheter Closure of Patent Foramen Ovale with a Novel Biodegradable Device: A Prospective, Multicenter, Randomized Controlled Clinical Trial." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20260112.347892

This week, please join author Robert Lookstein and Associate Editor Joshua Beckman as they discuss the article "Randomized Controlled Trial of Mechanical Thrombectomy With Anticoagulation Versus Anticoagulation Alone for Acute Intermediate-High Risk Pulmonary Embolism: Primary Outcomes From the STORM-PE Trial." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/10.1161/podcast.20260105.594056

This week, please join our guest hosts Peter Kennel and Gurleen Kaur as they interview the recipient of the 2025 James T. Willerson Award, Michael Waight and discuss his article, "Personalized Heart Digital Twins Detect Substrate Abnormalities in Scar-Dependent Ventricular Tachycardia." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20251229.893259

This week, join author Marcely Bonatto and Associate Editor Torbjørn Omland as they discuss the article "Sacubitril-Valsartan for the Prevention of Anthracycline Cardiotoxicity in Patients With Elevated Cardiac Troponin I Concentration During Chemotherapy: A Double-Blind Randomized Placebo-Controlled Clinical Trial: The SARAH Trial." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20251222.180775

This week, join author Vivek Reddy and Senior Associate Editor Sana Al-Khatib as they discuss the article "High-Voltage Focal Pulsed Field Ablation to Treat Scar-Related Ventricular Tachycardia: The First-in-Human VCAS Trial." For the episode transcript, visit:  https://www.ahajournals.org/do/10.1161/podcast.20251215.75602

This week, join author Sara Moura-Ferreira and Associate Editor Ntobeko Ntusi as they discuss the article "Prognostic Value of Exercise Right Ventricular-Pulmonary Arterial Coupling in Primary Mitral Regurgitation." For the episode transcript, visit:  https://www.ahajournals.org/do/10.1161/podcast.20251208.238882

This week, join author Hans-Josef Feistritzer and Associate Editor Stefan James as they discuss the article "Peri-Interventional Anesthesia Strategies for Transcatheter Aortic Valve Implantation: A Multicenter, Randomized, Controlled, Noninferiority Trial."   For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20251201.586148

This week, join author Jonas Oldgren and Associate Editor Torbjørn Omland as they discuss the article "Biomarker-Based ABC-AF Risk Scores for Personalized Treatment to Reduce Stroke or Death in Atrial Fibrillation: A Registry-Based Multicenter, Randomized, Controlled Study." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20251124.61165

This week, join Associate Editor and Editorialist Graeme Hankey as he discusses the article "Bailout Intracranial Angioplasty or Stenting After Thrombectomy for Acute Large Vessel Occlusion: 1-Year Outcomes of ANGEL-REBOOT and the editorial "Unsuccessful Thrombectomy During Acute Ischemic Stroke: Can It Be Rescued by Angioplasty and/or Stenting?" For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20251117.229007

This week, please join authors Shingo Fukuma and Yuichiro Mori as well as Associate Editor Shinya Goto as they discuss the article "Screening-Detected Atrial Fibrillation and Cardiovascular Outcomes in Working-Age Adults." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20251110.703752

This week, join author Rohan Khera and Associate Editor Nicholas Mills as they discuss the article "Phenotypic Selectivity of Artificial Intelligence-enhanced Electrocardiography in Cardiovascular Diagnosis and Risk Prediction." For the episode transcript, visit:  https://www.ahajournals.org/do/10.1161/podcast.20251103.917420

This week, Marc Ruel guest-hosts in this episode of Circulation on the Run as it features the annual Surgery Issue for Circulation. First, Marc is joined by author Duk-Hyun Kang as they discuss his article "Comparison of Long-Term Outcomes of Early Surgery Versus Conventional Treatment for Asymptomatic Severe Mitral Regurgitation: A Propensity Analysis." Then Marc is joined by authors Enoch Akowuah and Janelle Wagnild as they discuss their article "Accelerometer-Measured Physical Activity After Mitral Valve Surgery: An Analysis of the UK Mini Mitral Randomized Controlled Trial." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20251027.193601

This week, please join author Torbjørn Omland, as he discusses the article "Sacubitril/Valsartan and Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy: The PRADA II Randomized Clinical Trial." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20251020.442597  

This week, please join author Emily Lau, editorialist Sadiya Khan, and Associate Editor Kelly Chin as they discuss the article "Contemporary Burden of Cardiovascular Disease in Pregnancy: Insights From a Real-World Pregnancy Electronic Health Record Cohort" and the editorial "Bending the Curve in Maternal Mortality: Pregnancy as a Moment for Cardiovascular Disease Prevention." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20251013.381115

This week, please join author Emily Lau, editorialist Sadiya Khan, and Associate Editor Kelly Chin as they discuss the article "Contemporary Burden of Cardiovascular Disease in Pregnancy: Insights From a Real-World Pregnancy Electronic Health Record Cohort" and the editorial "Bending the Curve in Maternal Mortality: Pregnancy as a Moment for Cardiovascular Disease Prevention." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20251013.381115

This week, please join authors Joseph Campain and Gregory Lewis, as well as Section Editor Satyam "Tom" Sarma as they discuss the article "Characterization and Application of Novel Exercise Recovery Patterns That Reflect Cardiac Performance: A Substudy of the SEQUOIA-HCM Randomized Trial." For the episode transcript, visit: https://staging.www.ahajournals.org/do/10.1161/podcast.20251006.208532

This week please join author Gregory Hundemer, Editorialist Wanpen Vonpatanasin, and Associate Editor Torbjørn Omland as they discuss the article "Subclinical Primary Aldosteronism and Major Adverse Cardiovascular Events: A Longitudinal Population-Based Cohort Study" and the editorial "Subclinical Primary Aldosteronism: A Potential New Target in Cardiovascular Prevention?" For the episode transcript, visit:  https://www.ahajournals.org/do/10.1161/podcast.20250929.481570

This week please join author Chetan Huded as he discusses the article "Health Status Outcomes with Percutaneous Coronary Intervention and Coronary Artery Bypass Grafting in ISCHEMIA." For the episode transcript, visit:  https://www.ahajournals.org/do/10.1161/podcast.20250922.194514

This week, please join Daniel W. Jones as he discusses updates found in the 2025 AHA/ACC High Blood Pressure Guideline. This is an important episode to learn of the changes in guidelines and recommended practices in treating high blood pressure. For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250912.590432

This week please join author Daniele Giacoppo as he discusses the article "Transcatheter Aortic Valve Replacement With Balloon- Versus Self-Expandable Bioprostheses for the Treatment of Bicuspid Aortic Valve Stenosis." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250908.794818

This week please join author Rebecca Lawn and Associate Editor Mercedes Carnethon as they discuss the article "Experiences of Stalking and Obtaining a Restraining Order Are Associated With Onset of Cardiovascular Events in Women: A Prospective Analysis in the Nurses' Health Study II." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250902.860161