Podcasts about American Heart Association

Send us a message with this link, we would love to hear from you. Standard message rates may apply.The DASH diet offers a powerful, evidence-based approach to lowering blood pressure through nutritional changes rather than medication.• Stands for Dietary Approaches to Stop Hypertension• Focuses on fruits, vegetables, whole grains, lean proteins, and low-fat dairy• Limits sodium, saturated fat, added sugars, and processed meats• Can lower systolic blood pressure by 5-6 points and diastolic by 3 points• Recommends 4-5 servings each of fruits and vegetables daily• Suggests 6-8 servings of whole grains per day• Advises limiting sodium to 1,500mg daily for those with hypertension• Provides numerous meal ideas including oatmeal with berries, turkey sandwiches, and grilled salmon• Encourages using herbs and spices instead of salt for flavoring• Benefits extend beyond blood pressure to include improved cholesterol and weight managementFor more information about hypertension management, check out our previous episodes: episode 4 (explaining hypertension), episode 5 (lifestyle changes), episode 14 (common medications), and episode 33 (measuring blood pressure at home).References1. Diets. Yannakoulia M, Scarmeas N. The New England Journal of Medicine. 2024;390(22):2098-2106. doi:10.1056/NEJMra2211889.2. Treatment of Hypertension: A Review. Carey RM, Moran AE, Whelton PK. JAMA. 2022;328(18):1849-1861. doi:10.1001/jama.2022.19590.3. DASH Dietary Pattern and Cardiometabolic Outcomes: An Umbrella Review of Systematic Reviews and Meta-Analyses. Chiavaroli L, Viguiliouk E, Nishi SK, et al. Nutrients. 2019;11(2):E338. doi:10.3390/nu11020338.4. Primary Prevention of ASCVD and T2DM in Patients at Metabolic Risk: An Endocrine Society* Clinical Practice Guideline. Rosenzweig JL, Bakris GL, Berglund LF, et al. The Journal of Clinical Endocrinology and Metabolism. 2019;104(9):3939-3985. doi:10.1210/jc.2019-01338.5. Recommended Dietary Pattern to Achieve Adherence to the American Heart Association/American College of Cardiology (AHA/ACC) Guidelines: A Scientific Statement From the American Heart Association. Van Horn L, Carson JA, Appel LJ, et al. Circulation. 2016;134(22):e505-e529. doi:10.1161/CIR.0000000000000462.6. Dietary Approaches to Stop Hypertension (DASH) for the Primary and Secondary Prevention of Cardiovascular Diseases. Bensaaud A, Seery S, Gibson I, et al. The Cochrane Database of Systematic Reviews. 2025;5:CD013729. doi:10.1002/14651858.CD013729.pub2.7. Popular Dietary Patterns: Alignment With American Heart Association 2021 Dietary Guidance: A Scientific Statement From the American Heart Association. Gardner CD, Vadiveloo MK, Petersen KS, et al. Circulation. 2023;147(22):1715-1730. doi:10.1161/CIR.0000000000001146.8. Dietary Approaches to Prevent and Treat Hypertension: A Scientific Statement From the American Heart Association. Appel LJ, Brands MW, Daniels SR, et al. Hypertension (Dallas, Tex. : 1979). 2006;47(2):296-308. doi:10.1161/01.HYP.0000202568.01167.B6.9. Dietary Approaches to Stop Hypertension (DASH): Potential Mechanisms of Action Against Risk Factors of the Metabolic Syndrome. Akhlaghi M. Nutrition Research Reviews. 2020;33(1):1-18. doi:10.1017/S0954422419000155.10. The Effects of the Dietary Approaches to Stop Hypertension (DASH) Diet on Metabolic Risk Factors in Patients With Chronic Disease: Support the showSubscribe to Our Newsletter! Production and Content: Edward Delesky, MD & Nicole Aruffo, RNArtwork: Olivia Pawlowski

Join us as Katrina McGhee—Chief Marketing Officer at the American Heart Association, award-winning podcast host, and best-selling author—shares her transformative approach to self-care. In this episode, Katrina unpacks how small, intentional daily rituals can rebuild resilience, even when prioritizing yourself feels impossible. From powerful mindset shifts to actionable habits, discover how to reclaim your well-being with grace, courage, and consistency. Perfect for anyone ready to make self-care real and sustainable—starting today.

Join us for this episode of Digital Health Talks' "Five Good Things" where hosts Megan Antonelli and Janae Sharp discuss Samsung's acquisition of Xealth, Hartford Healthcare's first-in-US airport telehealth kiosk at Bradley International, and Rock Health's report showing $6.4 billion in healthcare investments with 62% going to AI startups. They also highlight nursing innovation awards, recognize Microsoft's Chief Nursing Officer Kathy McGrath, and announce their partnership with Emerge Americas for a major healthcare trade show in Miami, showcasing the continued momentum in digital health innovation and consumer-focused healthcare solutions.Janae Sharp, Founder & CEO, The Sharp IndexMegan Antonelli, Founder & CEO, HealthIMPACT Live

Nutrition scientist Dr. Christopher Gardner is at the forefront of the debate on ultra processed foods (UPFs). Some experts say you should avoid them entirely, while others (including the American Heart Association) argue that certain processed foods can fit into a healthy diet.   Dr. Gardner joins Chuck Carroll at the International Conference on Nutrition and Medicine (ICNM) to help cut through the confusion and conflicting advice.   In this episode of The Exam Room Podcast, you'll learn:   - What “ultra processed foods” really are - Why not all UPFs are equally harmful - The surprising reasons some healthier foods cost more - The top food additives and ingredients to avoid - How to read labels to make smarter choices   If you feel like you've raised your health IQ, please leave a 5-star rating and nice review on Apple Podcasts or Spotify.   Discover Dr. Neal Barnard's advice about which processed foods are healthy.   About Us The Physicians Committee is dedicated to saving lives through plant-based diets and ethical and effective scientific research. We combine the clout and expertise of more than 17,000 physicians with the dedicated actions of more than 175,000 members across the United States and around the world.

ICYMI: Hour Two of ‘Later, with Mo'Kelly' Presents – 'Wellness Wednesday' with wife, mother, fitness expert, masterful storyteller & regular guest contributor Claudine Cooper AKA ‘The Nice Exercise Lady' weighing in on the American Heart Association awarding wellness grants to 69 schools across the country in an effort to support “healthier learning environments” AND the proper way to make a PB&J…PLUS – Residents of a Southern California nudist resort are livid over new rules forcing them to either wear clothes or face eviction - on KFI AM 640…Live everywhere on the iHeartRadio app & YouTube @MrMoKelly

ICYMI: ‘Later, with Mo'Kelly' Presents – 'Wellness Wednesday' with wife, mother, fitness expert, masterful storyteller & regular guest contributor Claudine Cooper AKA ‘The Nice Exercise Lady' weighing in on the American Heart Association awarding wellness grants to 69 schools across the country in an effort to support “healthier learning environments” AND the proper way to make a PB&J - on KFI AM 640…Live everywhere on the iHeartRadio app & YouTube @MrMoKelly

RFK Jr. issues sharpest ultimatum yet to medical schools: “Start teaching nutrition now or face penalties!” Fast-food outlets continue to abound in teaching hospitals; Once serious causes of flank pain are ruled out, patients are often left to fend for themselves; Potatoes don't increase risk of diabetes—unless you eat French fries; Deep-frying in seed oils can yield harmful byproducts—but so, too, when you substitute with lard; As doctors get more aggressive treating blood pressure, how to minimize medication side effects; New study shows beetroot juice can lower BP by 7 points.

Welcome back, I start with The Update on my week, including the amazing wedding, a message from the American Heart Association, and some ups and downs. I then go to Mannys a Reel Boy where I may be put in jail for what I played. Well see. I end with Poke My Jokes at the last Kashan mic evidently. It was fun and time to move on. Anyway I hope you rate, review, and share this! See you next week God Willing! IA!

Host Jeremy C. Park talks with Missy Acosta, Senior Vice President of Brand Experience for Delta Dental of Tennessee, and Adam English, General Manager and Chief Operating Officer with the Nashville Sounds, who highlight the origins and evolution of the annual Kids Dental Day, which has grown over the last four years to include a number of partnerships providing shoe and book distributions and a variety of educational activities that serve hundreds of kids across Middle Tennessee at First Horizon Park baseball stadium.In 2022, the Nashville Sounds partnered with Delta Dental of Tennessee to create Kids Dental Day as a way to foster a day of fun and provide dental care and other related services to kids in need. Over the years, the event has expanded greatly thanks to a number of partnerships with organizations like cityCURRENT, Samaritan's Feet, Kroger, Higginbotham Insurance, Meharry Medical College, Neighborhood Health, Hope Smiles, Book'em, Nashville PBS, American Heart Association, the Adventure Science Center, Henry Schein, Dunkin' Donuts, and more. As a result, the event has evolved from providing simple dental screenings to a comprehensive day of care including dental check-ups and cleanings, a shoe distribution, new books, and tons of fun educational activities designed to help prepare the kids for the new school year ahead.During the interview, Missy and Adam talk about how the event has grown significantly over four years, the power of collaborating with multiple partners and services, including participation from dental students, local businesses, and community organizations, and what the event means to the kids served. They discuss plans to further expand the event's reach and impact by adding more partners and services, while emphasizing the importance of long-term commitment and advance planning for logistics and participation.Visit www.KidsDentalDay.com to learn more about the annual Kids Dental Day and how your nonprofit or company can get involved.Visit https://deltadentaltn.com to learn more about Delta Dental of Tennessee. You can also visit https://deltadentaltn.com/kids-dental... for Kids Dental Day.Visit www.NashvilleSounds.com or https://www.milb.com/nashville for more information about the Nashville Sounds and their season and game schedule.

In this episode of Taking Healthcare by Storm, Quality Insights Medical Director Dr. Jean Storm speaks with Erin Woodford, MSN, RN,  a member of the Skilled Nursing Facility Heart Failure Certification oversight work group with the American Heart Association and  Vice President of Population Health for Genesis Healthcare.Erin discusses the American Heart Association's Skilled Nursing Facility Heart Failure Certification, which improves care quality, reduces hospital readmissions, and supports better outcomes for residents. She highlights the importance of early detection, staff training, standardized protocols, and family education in managing heart failure within long-term care. Learn more about American Heart Association Certified Care™.If you have any topics or guests you'd like to see on future episodes, reach out to us on our website.Publication number QI-082925-GK

Heart disease is the world's biggest killer—and it often strikes without warning. It's responsible for around 1 in 5 deaths in the US. While these figures are deeply worrying, heart disease is not inevitable.  Decades of research have unearthed many of the risk factors associated with heart health, like poor diet or a sedentary lifestyle. In this episode, Dr. Nour Makarem outlines the latest scientific discoveries in this field and unveils some less-familiar risk factors. Drawing from large-scale population data and the latest wearable tech, she uncovers what makes heart disease so hard to spot, and what we can do today to prevent it.  Nour is a cardiovascular epidemiologist at Columbia University, whose research focuses on how our behaviors—like sleep, stress, and daily rhythms—impact heart disease risk. Her research has helped shape the American Heart Association's Essential Eight guide to heart health. Unwrap the truth about your food

Hunter-gatherers ate dozens of different plants each day! How can we use variety to maximize our health in the modern day, even while the American Heart Association asks us to limit the variety of what we eat?!? Also, how do you react when you take health-affirming steps? Do you diminish their power or do you celebrate and elevate them? Regardless, we'll talk about how to tweak our small steps mindset for maximum impact! This is a re-airing of a prior episode -- I find the topics of variety, mindfulness/stress reduction and gratitude infinitely impactful to making lifestyle changes!! LET'S TALK THE WALK! ***NEW*** Facebook Group for Our Community! Join here for support, motivation and fun! Wellness While Walking Facebook page Wellness While Walking on Instagram Wellness While Walking on Twitter Wellness While Walking website for show notes and other information wellnesswhilewalking@gmail.com     RESOURCES AND SOURCES (some links may be affiliate links) MY FAVORITE WELLNESS TOOL: The One-Minute Gratitude Journal, Brenda Nathan VARIETY: THE GOOD, THE BAD AND THE BROKEN A Diverse Diet May Not Be The Healthiest One, heart.org 7 Ways Variety Can Help Make Healthy Eating Easier, karencollinsnutrition.com A Big Fat Crisis: The Hidden Forces Behind the Obesity Epidemic --and How We Can End It, Deborah Cohen CELEBRATING, SAVORING AND SHARING WINS, BIG AND SMALL These 8 Simple Rules of Leadership From Jack Welch Are More Important Now Than Ever Before, inc.com What is the Negativity Bias, and How Can It Be Overcome? positivepsychology.com Creating Your Best Life, Caroline Adams Miller WALKING/GRATITUDE How to Walk, Thich Nhat Hanh MY FAVORITE WELLNESS TOOL: The One-Minute Gratitude Journal, Brenda Nathan VARIETY: THE GOOD, THE BAD AND THE BROKEN A Diverse Diet May Not Be The Healthiest One, heart.org 7 Ways Variety Can Help Make Healthy Eating Easier, karencollinsnutrition.com A Big Fat Crisis: The Hidden Forces Behind the Obesity Epidemic --and How We Can End It, Deborah Cohen CELEBRATING, SAVORING AND SHARING WINS, BIG AND SMALL These 8 Simple Rules of Leadership From Jack Welch Are More Important Now Than Ever Before, inc.com What is the Negativity Bias, and How Can It Be Overcome? positivepsychology.com Creating Your Best Life, Caroline Adams Miller WALKING/GRATITUDE How to Walk, Thich Nhat Hanh HOW TO SHARE WELLNESS WHILE WALKING Tell a friend or family member about Wellness While Walking, maybe while you're walking together or lamenting not feeling 100% Follow up with a quick text with more info, as noted below! (My favorite is pod.link/walking because it works with all the apps!) Screenshot a favorite episode playing on your phone and share to social media or to a friend via text or email! Wellness While Walking on Apple – click the up arrow to share with a friend via text or email, or share to social media Wellness While Walking on Spotify -- click the up arrow to share with a friend via text or email, or share to social media Use this universal link for any podcast app: pod.link/walking – give it to friends or share on social media Tell your pal about the Wellness While Walking website Thanks for listening and now for sharing! : )   DISCLAIMER Neither I nor many of my podcast guests are doctors or healthcare professionals of any kind, and nothing on this podcast or associated content should be considered medical advice. The information provided by Wellness While Walking Podcast and associated material, by Whole Life Workshop and by Bermuda Road Wellness LLC is for informational and entertainment purposes only. It is not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment, and before undertaking a new health care regimen, including walking.     Thanks for listening to Wellness While Walking, a walking podcast and a "best podcast for walking"!    

Marcy Syms has led a remarkable life, full of triumphs and tragedies.  Through a discussion of her new book, Leading with Respect: Adventures of an Off-Price Fashion Pioneer, host Bill Burke and Marcy cover subjects ranging from Marcy's upbringing, to overcoming bigotry and bullying in high school, to running her father's company and keeping it on track through the loss of two of her siblings.      Chapters: 00:00 Introduction & Leading with Respect  Bill Burke introduces Marcy Syms, CEO of The Syms Corporation, and her upcoming book “Leading with Respect.” Marcy discusses her father's motto “Don't let the bad guys win” and how it relates to being prepared and ensuring both sides of an encounter feel respected.  04:18 Customer Respect & Grandmother's Influence  Marcy explains how her father's tagline “an educated consumer is our best customer” was foundational to their company's success and built on respect for the customer. She also shares the significant influence of her Romanian immigrant grandmother, who instilled in her the importance of financial independence for young women.  09:12 Overcoming Antisemitism  Marcy recounts the overt antisemitism her family faced after moving to Westchester County, detailing the anxiety and fear it caused. She explains how she decided to ‘tough it out' like a job, overcompensating for the prejudice and becoming a rebel to challenge stereotypes.  13:47 Trailblazing & Joining the Family Business  Marcy discusses how she, as a 12-year-old, trailblazed by pushing for a Bat Mitzvah in her Conservative synagogue, which didn't traditionally hold them. She also explains her path to joining her father's business after being fired from her broadcasting job, finding excitement and fulfillment in the entrepreneurial world.  19:05 Business Innovation & Personal Resilience  Marcy describes the unique “automatic markdown price tag” marketing strategy that differentiated Syms stores, despite not being a profit center. She then discusses the immense personal resilience required to lead the company as CEO while simultaneously dealing with the tragic loss of her brother and sister within a year.  27:43 Courage, Values, and Philanthropy  Marcy emphasizes the importance of courage, even in small acts, and how it's linked to personal values. She reveals her strong aversion to bullies, a trait honed by her past experiences, and how her father's philanthropic vision led to the establishment of the Sy Syms Foundation.  33:25 Impactful Philanthropic Initiatives  Marcy details the foundation's unique philanthropic approach, supporting organizations like PEN America, the American Heart Association's “Go Red” campaign for women's heart health, and the Tannenbaum Foundation's anti-bullying initiatives. She also highlights their commitment to investigative journalism through NPR and scientific research at institutions like the Weissman Institute.  41:34 Lifelong Learning & Hot Water Strength  Marcy reflects on the Eleanor Roosevelt quote, “A woman is like a tea bag; you don't know her strength until she gets into hot water,” acknowledging her own life's challenges. She passionately advocates for lifelong learning as a key to longevity and a fulfilling life, drawing parallels to Jewish cultural inquisitiveness and the entrepreneurial spirit. 

In this special episode on Strategies for Staying Full and Satisfied, our host, Dr. Neil Skolnik will moderate a discussion with Lily Correa, registered dietitian about communicating strategies for staying full and satisfied. This special edition of Diabetes Core Update is sponsored by Avocados - Love One Today ®.    For more information, as well as diabetes-friendly mean plans and a free downloadable toolkit just go to:http://loveonetoday.com/SatisfiedEating Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health Lilian (Lily) M. Correa, Lily Correa is a registered dietitian and diplomate of the American College of Lifestyle Medicine   Resources and References:   Henning, Susanne M. et al. Hass Avocado Inclusion in a Weight-Loss Diet Supported Weight Loss and Altered Gut Microbiota: A 12-Week Randomized, Parallel-Controlled Trial. Current Developments in Nutrition 2019, Volume 3, Issue 8, ISSN 2475-2991. https://doi.org/10.1093/cdn/nzz068.   Khan, Naiman A. et al. Avocado Consumption, Abdominal Adiposity, and Oral Glucose Tolerance Among Persons with Overweight and Obesity. The Journal of Nutrition 2021, Volume 151, Issue 9p2513-2521. https://doi.org/10.1093/jn/nxab187.   Lichtenstein, Alice H. et al. Effect of Incorporating 1 Avocado Per Day Versus Habitual Diet on Visceral Adiposity: A Randomized Trial. Journal of the American Heart Association 2022, Volume 11, Number 14. https://doi.org/10.1161/JAHA.122.02565.   Pacheco, Lorena S. et al. Effects of Different Allotments of Avocados on the Nutritional Status of Families: A Cluster Randomized Controlled Trial. Nutrients 2021, 13(11), 4021. https://doi.org/10.3390/nu13114021.   Senn, MacKenzie K. et al. Associations between avocado intake and measures of glucose and insulin homeostasis in Hispanic individuals with and without type 2 diabetes: Results from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Nutrition, Metabolism and Cardiovascular Diseases 2023, Volume 33, Issue 12, 2428 – 2439. https://doi.org/10.1016/j.numecd.2023.08.002.   Wood, Alexis C. et al. Associations between Metabolomic Biomarkers of Avocado Intake and Glycemia in the Multi-Ethnic Study of Atherosclerosis. The Journal of Nutrition 2023, Volume 153, Issue 10, 2797 – 2807. https://doi.org/10.1016/j.tjnut.2023.07.013.   For more resources, research and recipes visit LoveOneToday.com/healthprofessionals.

In this episode of Risky Benefits, the focus is on heart health, community wellness, and leadership beyond boardrooms. The guest, Hailey Bruce, Development Director at the American Heart Association, shares her personal journey with congenital heart defects and her professional dedication to cardiovascular health. Hailey discusses the American Heart Association's efforts in research, community engagements like the Big Bend Heart Walk, and new initiatives targeting health in the construction industry. The episode also touches on the importance of mental health, stress management, and the wide-ranging impact of cardiovascular research.To listen in and subscribe to more episodes, visit our website: fbmc.com/podcast.

William H. Sauer, MD, FHRS, Brigham and Women's Hospital is joined by Wendy S. Tzou, MD, FHRS, University of Colorado Anschutz Medical Campus and Kishan Padalia, MD, University of Colorado, to discuss the results of ablation of sustained monomorphic ventricular tachycardia (SMVT) are suboptimal. For many patients with implantable cardioverter-defibrillators (ICDs), ICD electrograms (ICD-EGs) provide the only available information on SMVT. ICD-EGs have the ability to distinguish morphologically distinct SMVT and can be used for pace mapping.  https://www.hrsonline.org/education/TheLead https://www.jacc.org/doi/10.1016/j.jacc.2024.10.104 Host Disclosure(s): W. Sauer:  Honoraria/Speaking/Consulting: Biotronik, Biosense Webster, Inc., Abbott, Boston Scientific, Research: Medtronic  Contributor Disclosure(s): W. Tzou: Honoraria/Speaking/Consulting: Medtronic, Biotronik, Biosense Webster, Inc., Mediasphere Medical, Kardium, American Heart Association, Medtronic, Abbott, BioTelemetry, Boston Scientific, Kardium Research: Abbott Medical K. Padalia: Nothing to disclose.

The American Academy of Pediatrics release their own immunization schedule; The American Heart Association update 2017 guidelines for the prevention of high blood pressure; weight loss drug gains indication to treat noncirrhotic MASH; FDA approve a new fibromyalgia treatment; investigational SCD Tx to meet trial endpoint.

In the second half of this two part episode, Dr. David Leon unpacks some of the most hotly debated topics in resuscitation—fluids, blood products, ECMO, and post-arrest care. He breaks down the pros and cons of crystalloids (yes, even the “pasta water” debate), explains why lactated Ringer's is often preferred over normal saline, and dips into the use of albumin and colloids. Dr. Leon also discusses the promise and challenges of extracorporeal life support (ECLS), the evolving role of targeted temperature management (TTM), and even peeks into what advances the future might hold. It's a thoughtful, forward-looking conversation every resuscitationist should hear. What do you think of Dr. Leon's tips? Are you using these tools in your practice? We'd love to hear from you. Share them with us on social media @empulsepodcast or connect with us on ucdavisem.com Hosts: Dr. Julia Magaña, Professor of Pediatric Emergency Medicine at UC Davis Dr. Sarah Medeiros, Professor of Emergency Medicine at UC Davis Guest: Dr. David Leon, Assistant Professor of Emergency Medicine and Anesthesia at UC Davis Resources: American Heart Association (AHA) Algorithms Perman SM, Elmer J, Maciel CB, Uzendu A, May T, Mumma BE, Bartos JA, Rodriguez AJ, Kurz MC, Panchal AR, Rittenberger JC; American Heart Association. 2023 American Heart Association Focused Update on Adult Advanced Cardiovascular Life Support: An Update to the American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2024 Jan 30;149(5):e254-e273. doi: 10.1161/CIR.0000000000001194. Epub 2023 Dec 18. PMID: 38108133. **** Thank you to the UC Davis Department of Emergency Medicine for supporting this podcast and to Orlando Magaña at OM Productions for audio production services.

This is a hybrid heart disease risk factor post of a podcast with Prof Bruce Lanphear on lead and a piece I was asked to write for the Washington Post on risk factors for heart disease.First, the podcast. You may have thought the problem with lead exposure was circumscribed to children, but it's a much bigger issue than that. I'll concentrate on the exposure risk to adults in this interview, including the lead-estrogen hypothesis. Bruce has been working on the subject of lead exposure for more than 30 years. Let me emphasize that the problem is not going away, as highlighted in a recent New England Journal of Medicine piece on lead contamination in Milwaukee schools, “The Latest Episode in an Ongoing Toxic Pandemic.”Transcript with links to the audio and citationsEric Topol (00:05):Well, hello. This is Eric Topol with Ground Truths, and I'm very delighted to welcome Professor Bruce Lanphear from Simon Fraser University in British Columbia for a very interesting topic, and that's about lead exposure. We tend to think about lead poisoning with the Flint, Michigan, but there's a lot more to this story. So welcome, Bruce.Bruce Lanphear (00:32):Thank you, Eric. It's great to be here.Eric Topol (00:33):Yeah. So you had a New England Journal of Medicine (NEJM) Review in October last year, which was probably a wake up to me, and I'm sure to many others. We'll link to that, where you reviewed the whole topic, the title is called Lead Poisoning. But of course it's not just about a big dose, but rather chronic exposure. So maybe you could give us a bit of an overview of that review that you wrote for NEJM.Bruce Lanphear (01:05):Yeah, so we really focused on the things where we feel like there's a definitive link. Things like lead and diminished IQ in children, lead and coronary heart disease, lead and chronic renal disease. As you mentioned, we've typically thought of lead as sort of the overt lead poisoning where somebody becomes acutely ill. But over the past century what we've learned is that lead is one of those toxic chemicals where it's the chronic wear and tear on our bodies that catches up and it's at the root of many of these chronic diseases that are causing problems today.Eric Topol (01:43):Yeah, it's pretty striking. The one that grabbed me and kind of almost fell out of my chair was that in 2019 when I guess the most recent data there is 5.5 million cardiovascular deaths ascribed to relatively low levels, or I guess there is no safe level of lead exposure, that's really striking. That's a lot of people dying from something that cardiology and medical community is not really aware of. And there's a figure 3 [BELOW] that we will also show in the transcript, where you show the level where you start to see a takeoff. It starts very low and by 50 μg/liter, you're seeing a twofold risk and there's no threshold, it keeps going up. How many of us do you think are exposed to that type of level as adults, Bruce?Bruce Lanphear (02:39):Well, as adults, if we go back in time, all of us. If you go back to the 1970s when lead was still in gasoline, the median blood lead level of Americans was about 13 to 15 µg/dL. So we've all been exposed historically to those levels, and part of the reason we've begun to see a striking decline in coronary heart disease, which peaked in 1968. And by 1978, there was a 20% decline, 190,000 more people were alive than expected. So even in that first decade, there was this striking decline in coronary heart disease. And so, in addition to the prospective studies that have found this link between an increase in lead exposure and death from cardiovascular disease and more specifically coronary heart disease. We can look back in time and see how the decline in leaded gasoline led to a decline in heart disease and hypertension.Eric Topol (03:41):Yeah, but it looks like it's still a problem. And you have a phenomenal graph that's encouraging, where you see this 95% reduction in the lead exposure from the 1970s. And as you said, the factors that can be ascribed to like getting rid of lead from gasoline and others. But what is troubling is that we still have a lot of people that this could be a problem. Now, one of the things that was fascinating is that you get into that herbal supplements could be a risk factor. That we don't do screening, of course, should we do screening? And there's certain people that particularly that you consider at high risk that should get screened. So I wasn't aware, I mean the one type of supplements that you zoomed in on, how do you say it? Ayurvedic?Supplements With LeadBruce Lanphear (04:39):Oh yeah. So this is Ayurvedic medicine and in fact, I just was on a Zoom call three weeks ago with a husband and wife who live in India. The young woman had taken Ayurvedic medicine and because of that, her blood lead levels increased to 70 µg/dL, and several months later she was pregnant, and she was trying to figure out what to do with this. Ayurvedic medicine is not well regulated. And so, that's one of the most important sources when we think about India, for example. And I think you pointed out a really important thing is number one, we don't know that there's any safe level even though blood lead levels in the United States and Europe, for example, have come down by over 95%. The levels that we're exposed to and especially the levels in our bones are 10 to 100 times higher than our pre-industrial ancestors.Bruce Lanphear (05:36):So we haven't yet reached those levels that our ancestors were exposed to. Are there effects at even lower and lower levels? Everything would suggest, we should assume that there is, but we don't know down below, let's say one microgram per deciliter or that's the equivalent of 10 parts per billion of lead and blood. What we also know though is when leaded gasoline was restricted in the United States and Canada and elsewhere, the companies turned to the industrializing countries and started to market it there. And so, we saw first the epidemic of coronary heart disease in the United States, Canada, Europe. Then that's come down over the past 50 years. At the same time, it was rising in low to middle income countries. So today over 95% of the burden of disease from lead including heart disease is found in industrializing countries.Eric Topol (06:34):Right. Now, it's pretty striking, of course. Is it true that airlines fuel is still with lead today?Bruce Lanphear (06:45):Well, not commercial airlines. It's going to be a small single piston aircraft. So for example, when we did a study down around the Santa Clara County Airport, Reid-Hillview, and we can see that the children who live within a half mile of the airport had blood lead levels about 10% higher than children that live further away. And the children who live downwind, 25% higher still. Now, nobody's mapped out the health effects, but one of the things that's particularly troubling about emissions from small aircraft is that the particle size of lead is extraordinarily small, and we know how nanoparticles because they have larger surface area can be more problematic. They also can probably go straight up into the brain or across the pulmonary tissues, and so those small particles we should be particularly worried about. But it's been such a long journey to try to figure out how to get that out of aircraft. It's a problem. The EPA recognized it. They said it's an endangerment, but the industry is still pushing back.Eric Topol (07:55):Yeah, I mean, it's interesting that we still have these problems, and I am going to in a minute ask you what we can do to just eradicate lead as much as possible, but we're not there yet. But one study that seemed to be hard to believe that you cited in the review. A year after a ban leaded fuel in NASCAR races, mortality from coronary heart disease declined significantly in communities near racetracks. Can you talk about that one because it's a little bit like the one you just mentioned with the airports?Bruce Lanphear (08:30):Yeah. Now that study particularly, this was by Alex Hollingsworth, was particularly looking at people over 65. And we're working on a follow-up study that will look at people below 65, but it was quite striking. When NASCAR took lead out of their fuel, he compared the rates of coronary heart disease of people that live nearby compared to a control group populations that live further away. And he did see a pretty striking reduction. One of the things we also want to look at in our follow-up is how quickly does that risk begin to taper off? That's going to be really important in terms of trying to develop a strategy around preventing lead poisoning. How quickly do we expect to see it fall? I think it's probably going to be within 12 to 24 months that we'll see benefits.Eric Topol (09:20):That's interesting because as you show in a really nice graphic in adults, which are the people who would be listening to this podcast. Of course, they ought to be concerned too about children and all and reproductive health. But the point about the skeleton, 95% of the lead is there and the main organs, which we haven't mentioned the kidney and the kidney injury that occurs no less the cardiovascular, the blood pressure elevation. So these are really, and you mentioned not necessarily highlighted in that graphic, but potential cognitive hit as well. You also wrote about how people who have symptoms of abdominal pain, memory impairment, and high blood pressure that's unexplained, maybe they should get a blood level screening. I assume those are easy to get, right?Bruce Lanphear (10:17):Oh yeah, absolutely. You can get those in any hospital, any clinic across the country. We're still struggling with having those available where it's most needed in the industrializing countries, but certainly available here. Now, we don't expect that for most people who have those symptoms, lead poisoning is going to be the cause, right. It'd still be unusual unless you work in an industry, for example, smelting batteries to recycle them. We don't expect it to be real common, and we're not even sure, Eric, whether we should be doing widespread screening. If I looked at this as a population scientist, the real focus should be on identifying the sources. We mostly know where those are here and radically moving it down. Getting rid of the lead service lines, which was such a big part of what President Biden was doing, and it was perfect. For every dollar invested to reduce lead exposure from those lead service lines. Ronnie Levin at Harvard said there'd be a 35-fold return in cost, benefits really, and this has always been true, that reducing lead exposure throughout the past 40 years has always been shown to be amazingly cost beneficial. The problem is operating within a free market health system, even though there's tremendous social benefits, that benefit isn't going to be monetized or privatized. And so, who's going to make those decisions? We hope our government is, but that doesn't always play out.Eric Topol (11:52):Well. What's interesting is, as opposed to the problems we have today that are prominent such as the microplastic, nanoplastics, the air pollution, the forever chemicals, that just keep getting worse, I mean, they are just cumulative. This one, there was tremendous improvement, but it's still not enough. And I guess you're zooming in on the lead lines. That'd be the most important thing to work on today. Another thing that has come up, there's been trials, as you may I'm sure, because all over this field of chelation, there's a trial that was run by the NIH, supported by NH that looked at chelation to prevent coronary disease. Is there any evidence that people who have a problem with lead would benefit from chelation therapy?Bruce Lanphear (12:44):Well, there's two major studies that have been done, and Tony Lamas was in charge of both of them. The first one Trial to Assess Chelation Therapy (TACT) study, it was a randomized controlled trial, not intended specifically to focus on lead, but rather it was to look at sort of this alternative therapy. They found significant benefits about an 18% reduction in subsequent cardiac events. That led to a second study that was just published last year, and it was focused on people who had diabetes. They saw some benefit, but it wasn't significant. So whether that's because there wasn't enough variability and exposure, it's not entirely clear, but we've seen this with lead in IQ deficits in kids where we can show that we can reduce blood lead levels. But ultimately what tends to happen is once you've taken lead out of the blood, some of it's released again from the bone, but you still have all that lead in the bone that's there. You get some of it out, but you're not going to get the bulk of it out.The Lead-Estrogen HypothesisEric Topol (13:47):Right. It's a reservoir that's hard to reckon with. Yeah. Now another thing, you have a Substack that is called Plagues, Pollution & Poverty, and you wrote a really provocative piece in that earlier and April called How Estrogen Keeps Lead - and Heart Attacks - in Check, and basically you got into the lead estrogen hypothesis.Eric Topol (14:10):Can you enlighten us about that?Bruce Lanphear (14:12):Yeah. A lot of the seminal work in this area was done by Ellen Silbergeld, who's a brilliant and somewhat peculiar toxicologist and Ellen for years, I focused on childhood lead exposure, and for years Ellen would tell me, almost demolish me for not studying adults. And because she had found back in 1988 that as women go into menopause, their blood lead levels spike increased by about 30%, and that's where most of our lead is stored is in our bone. And so, as I was thinking about this, it all became clear because blood lead levels in boys and girls is about the same. It's comparable up until menarche, and then girls young women's blood leads fall by about 20%. And they stay 20% lower throughout the reproductive years until menopause. And especially during those first few years around menopause, perimenopause, you see fairly striking increases in the weakening of the bone and blood lead levels.Bruce Lanphear (15:19):So that might very well help to explain why estrogen is protected, because what happens is throughout the reproductive life, women are losing a little bit of lead every month. And estrogen is at its lowest during that time, and that's going to be when blood lead is at its highest because estrogen pushes lead into the bone. Not only that, women lose lead into the developing fetus when they're pregnant. So what Ellen found is that there was less of a spike around menopause for the women that had three or four pregnancies because they had offloaded that into their babies. So all of this, if you put it together, and this is of course in a very short note of it, you can see that lead increases dyslipidemia, it leads to tears in the endothelium of the arterial wall, it's going to increase thrombosis. All of these things that we think of as the classic atherosclerosis. Well, what estrogen does is the opposite of those. It decreases dyslipidemia, it repairs the arterial endothelial wall. So how much of it is that estrogen is protective, and how much is it that it's moving lead out of the system, making it less biologically available?Eric Topol (16:46):Yeah, I know. It's really interesting. Quite provocative. Should be followed up on, for sure. Just getting to you, you're a physician and epidemiologist, MD MPH, and you have spent your career on this sort of thing, right? I mean, is your middle name lead or what do you work on all the time?Bruce Lanphear (17:09):Yeah, I've been doing this for about 30 years, and one of my mentors, Herb Needleman spent 40 years of his career on it. And in some ways, Eric, it seems to me particularly in these very difficult entrenched problems like lead, we don't have any pharmaceutical company reaching out to us to promote what we do. We've got industry trying to squash what we do.Bruce Lanphear (17:35):It really does take a career to really make a dent in this stuff. And in a way, you can look at my trajectory and it is really following up on what Herb Needleman did and what Clare Patterson did, and that was finding the effects at lower and lower levels. Because what we do with lead and most other toxic chemicals, the ones that don't cause cancer, is we assume that there's a safe level or threshold until we prove otherwise. And yet when you look at the evidence, whether it's about asbestos and mesothelioma, air pollution and cardiovascular mortality, lead and cardiovascular mortality, benzene and leukemia, none of those exhibit a threshold. In some cases, the risks are steepest proportionately at the lowest measurable levels, and that really raises some tremendous challenges, right? Because how are we going to bring air pollution or lead down to zero? But at the same time, it also provides these tremendous opportunities because we know that they're causing disease. We know what the sources are. If we could only bring about the political will to address them, we could prevent a lot of death, disease, and disability. I mean, about 20% of deaths around the world every year are from air pollution, lead, and other toxic chemicals, and yet the amount of money we invest in them is just paltry compared to what we invest in other things. Which is not to pit one against the other, but it's to say we haven't invested enough in these.Eric Topol (19:14):No, absolutely. I think your point, just to make sure that it's clear, is that even at low levels, this is of course where most of the population exposure would be, and that's why that's so incriminating. Now, one of the things I just want to end up with is that we know that these are tiny, tiny particles of lead, and then the question is how they can synergize and find particulate matter of air pollution in the nanoplastic, microplastic story and binding to forever chemicals, PFAS. How do you process all that? Because it's not just a single hit here, it's also the fact that there's ability to have binding to the other environmental toxins that are not going away.Bruce Lanphear (20:10):That's right. And in a way, when we talk about lead playing this tremendous role in the rise and decline of coronary heart disease, we can't entirely separate it out, for example, from air pollution or cigarette smoke for that matter, nor plastic. So for example, with air pollution, if we look at air pollution over the past century, up until the 1980s, even into the 1990s, it was leaded, right? So you couldn't separate them. If you look at cigarette smoke, cigarette tobacco in the 1940s and 1950s was grown in fields where they used lead arsenic as an insecticide. So smokers even today have blood lead levels that are 20% higher than non-smokers, and people who are not smokers but exposed to secondhand smoke have blood lead levels 20% higher than non-smokers who aren't exposed to secondhand smoke. So in a way, we should try to tease apart these differences, but it's going to be really challenging. In a way we can almost think about them as a spectrum of exposures. Now with plastics, you can really think of plastics as a form of pollution because it's not just one thing. There's all these additives, whether it's the PFAS chemicals or lead, which is used as a stabilizer. And so, all of them really are kind of integrated into each other, which again, maybe there's some opportunity there if we really were ready to tackle.Eric Topol (21:40):And interestingly, just yesterday, it was announced by the current administration that they're stopping all the prior efforts on the forever chemicals that were initiated in the water supply. And I mean, if there's one takeaway from our discussion, it's that we have to get all over this and we're not paying enough attention to our environmental exposures. You've really highlighted spotlighted the lead story. And obviously there are others that are, instead of getting somewhat better, they're actually going in the opposite direction. And they're all tied together that's what is so striking here, and they all do many bad things to our bodies. So I don't know how, I'm obviously really interested in promoting healthy aging, and unless we get on this, we're chasing our tails, right?Bruce Lanphear (22:31):Well, I think that's right, Eric. And I was reading the tips that you'd written about in preparation for your book release, and you focused understandably on what each of us can do, how we can modify our own lifestyles. We almost need six tips about what our government should do in order to make it harder for us to become sick, or to encourage those healthy behaviors that you talked about. That's a big part of it as well. One of the things we're celebrating the hundredth anniversary. This is not really something to celebrate, but we are. The hundredth anniversary of the addition of tetraethyl lead to gasoline. And one of the key things about that addition, there was this debate because when it was being manufactured, 80% of the workers at a plant in New Jersey suffered from severe lead poisoning, and five died, and it was enough that New York City, Philadelphia and New Jersey banned tetraethyl lead.Bruce Lanphear (23:31):Then there was this convening by the US Surgeon General to determine whether it was safe to add tetraethyl lead to gasoline. One scientist, Yandell Henderson said, absolutely not. You're going to create a scourge worse than tuberculosis with slow lead poisoning and hardening of your arteries. Robert Kehoe, who represented the industry said, we know lead is toxic, but until you've shown that it's toxic when added to gasoline, you have no right to prohibit us from using it. So that is now known as the Kehoe rule, and it's relevant not only for lead, but for PFAS, for air pollution, for all these other things, because what it set as a precedent, until you've shown that these chemicals or pollution is toxic when used in commerce, you have no right to prohibit industry from using it. And that's the fix we're in.Eric Topol (24:27):Well, it sounds too much like the tobacco story and so many other things that were missed opportunities to promote public health. Now, is Canada doing any better than us on this stuff?Bruce Lanphear (24:40):In some ways, but not in others. And one of the interesting thing is we don't have standards, we have guidelines. And amazingly, the cities generally try to conform to those guidance levels. With water lead, we're down to five parts per billion. The US is sticking around with ten parts per billion, but it's not even really very, it's not enforced very well. So we are doing better in some ways, not so good in other ways. The European Union, generally speaking, is doing much better than North America.Eric Topol (25:15):Yeah, well, it doesn't look very encouraging at the moment, but hopefully someday we'll get there. Bruce, this has been a really fascinating discussion. I think we all should be thankful to you for dedicating your career to a topic that a lot of us are not up on, and you hopefully are getting us all into a state of awareness. And congratulations on that review, which was masterful and keep up the great work. Thank you.Bruce Lanphear (25:42):Thank you, Eric. I appreciate it.________________________________________________My Recommendations for Preventing Heart Disease (Markedly Truncated from Text and Graphics Provided in SUPER AGERS)Recently the Washington Post asked me for a listicle of 10 ways to prevent heart disease. I generally avoid making such lists but many people have de-subscribed to this newspaper, never subscribed, or missed the post, so here it is with links to citations:Guest column by Eric Topol, MDThe buildup of cholesterol and other substances in the wall of our arteries, known as atherosclerosis, is common. It can lead to severe plaques that narrow the artery and limit blood flow, or to a crack in the artery wall that can trigger blood clot formation, resulting in a heart attack.While we've seen some major advances in treating heart disease, it remains the leading killer in the United States, even though about 80 percent of cases are considered preventable. There are evidence-based steps you can take to stave it off. As a cardiologist, here's what I recommend to my patients.1. Do both aerobic and resistance exerciseThis is considered the single most effective medical intervention to protect against atherosclerosis and promote healthy aging. Physical activity lowers inflammation in the body. Evidence has shown that both aerobic and strength training forms of exercise are important. But only 1 in 4 Americans meet the two activity guidelines from the American Heart Association: aerobic exercise of 150 minutes per week of at least moderate physical activity, such as walking, bicycling on level ground, dancing or gardening, and strength training for at least two sessions per week, which typically translates to 60 minutes weekly.The protective benefit of exercise is seen with even relatively low levels of activity, such as around 2,500 steps per day (via sustained physical activity, not starting and stopping), and generally increases proportionately with more activity. It used to be thought that people who exercise only on the weekend — known as “weekend warriors” — put themselves in danger, but recent data shows the benefits of exercise can be derived from weekend-only workouts, too.2. Follow an anti-inflammatory dietA predominantly plant-based diet — high in fiber and rich in vegetables, fruits and whole grains, as seen with the Mediterranean diet — has considerable evidence from large-scale observational and randomized trials for reducing body-wide inflammation and improving cardiovascular outcomes.Foods rich in omega-3 fatty acids, such as salmon, also form part of a diet that suppresses inflammation. On the other hand, red meat and ultra-processed foods are pro-inflammatory, and you should limit your consumption. High protein intake of more than 1.4 grams per kilogram of body weight per day — around 95 grams for someone who is 150 pounds — has also been linked to promoting inflammation and to atherosclerosis in experimental models. That is particularly related to animal-based proteins and the role of leucine, an essential amino acid that is obtained only by diet.3. Maintain a healthy weightBeing overweight or obese indicates an excess of white adipose tissue. This kind of tissue can increase the risk of heart disease because it stores fat cells, known as adipocytes, which release substances that contribute to inflammation.In studies, we've seen that glucagon-like peptide (GLP-1) drugs can reduce inflammation with weight loss, and a significant reduction of heart attacks and strokes among high-risk patients treated for obesity. Lean body weight also helps protect against atrial fibrillation, the most common heart rhythm abnormality.4. Know and avoid metabolic syndrome and prediabetesTied into obesity, in part, is the problem of insulin resistance and metabolic syndrome. Two out of three people with obesity have this syndrome, which is defined as having three out of five features: high fasting blood glucose, high fasting triglycerides, high blood pressure, low high-density lipoprotein (HDL) and central adiposity (waist circumference of more than 40 inches in men, 35 inches in women).Metabolic syndrome is also present in a high proportion of people without obesity, about 50 million Americans. Prediabetes often overlaps with it. Prediabetes is defined as a hemoglobin A1c (a measure of how much glucose is stuck to your red blood cells) between 5.7 and 6.4 percent, or a fasting glucose between 100 and 125 milligrams per deciliter.Both metabolic syndrome and prediabetes carry an increased risk of heart disease and can be prevented — and countered — by weight loss, exercise and an optimal diet.As the glucagon-like peptide drug family moves to pills and less expense in the future, these medications may prove helpful for reducing risk in people with metabolic syndrome and prediabetes. For those with Type 2 diabetes, the goal is optimizing glucose management and maximal attention to lifestyle factors.5. Keep your blood pressure in a healthy rangeHypertension is an important risk factor for heart disease and is exceptionally common as we age. The optimal blood pressure is 120/80 mm Hg or lower. But with aging, there is often an elevation of systolic blood pressure to about 130 mm Hg, related to stiffening of arteries. While common, it is still considered elevated.Ideally, everyone should monitor their blood pressure with a home device to make sure they haven't developed hypertension. A mild abnormality of blood pressure will typically improve with lifestyle changes, but more substantial elevations will probably require medications.6. Find out your genetic riskWe now have the means of determining your genetic risk of coronary artery disease with what is known as a polygenic risk score, derived from a gene chip. The term polygenic refers to hundreds of DNA variants in the genome that are linked to risk of heart disease. This is very different from a family history, because we're a product of both our mother's and father's genomes, and the way the DNA variants come together in each of us can vary considerably for combinations of variants.That means you could have high or low risk for heart disease that is different from your familial pattern. People with a high polygenic risk score benefit the most from medications to lower cholesterol, such as statins. A polygenic risk score can be obtained from a number of commercial companies, though it isn't typically covered by insurance.I don't recommend getting a calcium score of your coronary arteries via a computed tomography (CT) scan. This test is overused and often induces overwhelming anxiety in patients with a high calcium score but without symptoms or bona fide risk. If you have symptoms suggestive of coronary artery disease, such as chest discomfort with exercise, then a CT angiogram may be helpful to map the coronary arteries. It is much more informative than a calcium score.7. Check your blood lipidsThe main lipid abnormality that requires attention is low-density cholesterol (LDL), which is often high and for people with increased risk of heart disease should certainly be addressed. While lifestyle improvements can help, significant elevation typically requires medications such as a statin; ezetimibe; bempedoic acid; or injectables such as evolocumab (Repatha), alirocumab (Praluent) or inclisiran (Leqvio). The higher the risk, the more aggressive LDL lowering may be considered.It should be noted that the use of potent statins, such as rosuvastatin or atorvastatin, especially at high doses, is linked to inducing glucose intolerance and risk of Type 2 diabetes. While this is not a common side effect, it requires attention since it is often missed from lack of awareness.A low high-density lipoprotein (HDL) cholesterol often responds to weight loss and exercise. We used to think that high HDL was indicative of “good cholesterol,” but more recent evidence suggests that is not the case and it may reflect increased risk when very high.To get a comprehensive assessment of risk via your blood lipids, it's important to get the apolipoprotein B (apoB) test at least once because about 20 percent of people have normal LDL and a high apoB.Like low HDL, high fasting triglycerides may indicate insulin resistance as part of the metabolic syndrome and will often respond to lifestyle factors.The lipoprotein known as Lp(a) should also be assessed at least once because it indicates risk when elevated. The good news is scientists are on the cusp of finally having medications to lower it, with five different drugs in late-stage clinical trials.8. Reduce exposure to environmental pollutantsIn recent years, we've learned a lot about the substantial pro-inflammatory effects of air pollution, microplastics and forever chemicals, all of which have been linked to a higher risk of heart disease. In one study, microplastics or nanoplastics in the artery wall were found in about 60 percent of more than 300 people. Researchers found a vicious inflammatory response around the plastics, and a four- to fivefold risk of heart attacks or strokes during three years of follow-up.While we need policy changes to address these toxic substances in the environment, risk can be reduced by paying attention to air and water quality using filtration or purification devices, less use of plastic water bottles and plastic storage, and, in general, being much more aware and wary of our pervasive use of plastics.9. Don't smoke This point, it should be well known that cigarette smoking is a potent risk factor for coronary artery disease and should be completely avoided.10. Get Good SleepAlthough we tend to connect sleep health with brain and cognitive function, there's evidence that sleep regularity and quality are associated with less risk of heart disease. Regularity means adhering to a routine schedule as much as possible, and its benefit may be due to our body's preference for maintaining its circadian rhythm. Sleep quality — meaning with fewer interruptions — and maximal deep sleep can be tracked with smartwatches, fitness bands, rings or mattress sensors.Sleep apnea, when breathing stops and starts during sleep, is fairly common and often unsuspected. So if you're having trouble sleeping or you snore loudly, talk to your doctor about ruling out the condition. Testing for sleep apnea can involve checking for good oxygen saturation throughout one's sleep. That can be done through a sleep study or at home using rings or smartwatches that include oxygen saturation in their sensors and body movement algorithms that pick up disturbed breathing.Eric Topol, MD, is a cardiologist, professor and executive vice president of Scripps Research in San Diego. He is the author of “Super Agers: An Evidence-Based Approach to Longevity” and the author of Ground Truths on Substack.*********************°°°°°°°°°°°°°°°°°°°°Thanks to many of you Ground Truths subscribers who helped put SUPER AGERS on the NYT bestseller list for 4 weeks.Here are 2 recent, informative, and fun conversations I had on the topicMichael Shermer, The SkepticRuss Roberts, EconTalk I'm also very appreciative for your reading and subscribing to Ground Truths.If you found this interesting PLEASE share it!That makes the work involved in putting these together especially worthwhile.All content on Ground Truths—its newsletters, analyses, and podcasts, are free, open-access.Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don't hesitate to post comments and give me feedback. Let me know topics that you would like to see covered.Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past three years. Just a week ago we just had nearly 50 interns (high school, college and medical students) present posters of the work they did over the summer and it was exhilarating! Some photos below Get full access to Ground Truths at erictopol.substack.com/subscribe

Send us a textThis week's expert interview is with Dr. Emily Andaya, Medical Director of the Cardiovascular Program at Major Health Partners of Shelbyville, IN. She joins Louise Campbell and Roger Green to discuss the American Heart Assocation's CKM initiative, why she believe it should be titled "CKLM" for liver, and how including liver in the CKM scoring system would make it stronger and provide a more robust tool to help improve patients' health. Emily begins by discussing her attendance at the American Society for Preventive Cardiology meeting in Boston the previous weekend, where Dr. Christos Montzoros presented a talk proposing that the liver's role in cardiovascular diseases is "equally critical" compared to the kidney and other multi-metabolic co-morbidities. Dr. Montzoros closed his talk by stating that the CKM syndrome description should be changed to CKLM to reflect the importance of the liver, and that the CKLM patient scoring and criteria should reflect this as well.Next, Emily describes the 0-to-4 scoring system that the CKM initiative has chosen to use and the recommendations that accompany the scoring system itself. The system does not neatly overlay the 4-point fibrosis scoring system or the NAS score, but Emily describes how these might be incorporated into the CKM score. The conversation shifts to focus on patient management. Since the original CKM paper was published in 2023, resmetirom had not yet been approved and the paper itself focused more on screening than on treatment. To Emily, adding the "L" to CKM would entail adding resmetirom to treatment protocols as appropriate, and also considering drug combinations that addressed liver disease. Louise takes this issue from the other side, suggesting that every time a provider prescribes a drug to a CKM patient, the potential for negative liver effects should be part of the selection process. Emily and Louise agree that providers and patients should take a holistic approach to therapy for these patients. One benefit: even if a patient has multiple organs affected by multi-metabolic challenges, the provider can educate the patient that there is a single target disease to treat instead of multiple different diseases. As Roger notes, treating 4-5 discrete diseases simultaneously sounds overwhelming, while treating one overarching disease sounds far more manageable.The conversation ends with a focus on whether we are correctly identifying high-risk cardiovascular patients in the current environment, and how this more holistic focus might improve patient screening and identification.

Send us a text00:00:00 - Surf's Up: Season 6, Episode 11 This week, we modify our usual episode structure to focus on multi-metabolic practices and constructs. The multi-metabolic practices covered this week are run by non-hepatologists who have chosen to focus on the liver in a broader cardiometabolic context. They include two practices discussed during a two-part roundtable, one run by US gastroenterologist Dr. Karen Jerome-Zapadka and the EDOM practice in Spain, run by endocrinologists. The expert interview is with Dr. Emily Andaya, an internist who helms a cardiometabolic practice in Indiana, US, that focuses on the liver. 00:14:23 - Roundtable Part I: Groundbreaker and introductionThe core of the episodes started during the weekly groundbreakers, as guests began to describe the path that brought them from single-disease specialization to the broader multi-metabolic practice.. Immediately after the groundbreakers, participants describe their clinics today, including patient population and principles underlying their approach to treatment.00:26:15 - Roundtable Part II: Tools they useGuided by Louise, the specialists discuss the devices they use to screen and stage patients and the drugs they use to treat them. One interesting item that emerges is that EDOM relies on a 0-to-4 disease severity classification, but it does not align point-by-point with the 4-point fibrosis scale common in MASH. 00:40:28 - Roundtable Part III: Training Providers in the ClinicsLouise starts this segment by asking the EDOM team how they train practitioners in their clinic. EDOM trains practitioners in nutrition and technologists in the proper use of scanning devices. Karen comments that one big issue in re-training involves the length of visits: 15 minutes for a typical GI visit vs. 60 minutes for an initial multi-metabolic session and 30 minutes for follow-ups. Along with this, the information gathering technique are different.00:50:57 - Roundtable Part IV: Patient Health and Wrap-upLouise asks participants whether and how they have measured the impact the multi-metabolic approach has on patients' health (profound in both cases) and whether they are seeing an increase in HCC. Karen sees a difference among her long-term patients, while EDOM refers patients before their fibrosis reaches cirrhosis stage. In the last part of the episode, panelists share perspectives on how their initial specialties fit with the broader multi-metabolic practice and the kinds of impact they can have on patients.01:12:50 - Expert: Dr. Emily Andaya discusses US initiatives in multi-metabolic healthThis week's expert is Dr. Emily Andaya, an Indiana (US)-based internist whose practice has expanded to take on a multi-metabolic focus. She begins by discussing her recent attendance at the American Society for Preventive Cardiology (SPC) meeting in Boston, where she heard a talk by Dr. Christos Montzoros, an endocrinologist and multi-metabolic advocate, who emphasized the importance of incorporating the liver into preventive cardiology's focus. Louise and Emily agree that cardiometabolic focus involves evaluating general, overall health, but Emily discusses how this might require a deeper or broader testing protocol for each target organ. Emily describes the 4-point CKM scale and Louise asks how fibrosis or NAS scoring, as deployed in the MASH CRN system, might be valuable here. This is a far-ranging conversation, but one special point of interest involves the psychological benefit of telling a patient they need to treat one (multi-metabolic) condition, instead of separate heart, kidney, endocrinological and liver conditions, which might feel far more overwhelming. 01:48:48 - ConclusionBecause Roger is on vacation, there is no business report this week.

New guidelines from the American Heart Association and the American College of Cardiology suggest abstaining from alcohol to keep you healthy. Dr. Haitham Hussein joins the show to talk about the impact of alcohol on the body and ways to maintain a healthy lifestyle.

Doctors Group Praises American Heart Association Statement “Not All Ultra-Processed Foods Are Poor Nutritional Quality” “We are pleased to see the AHA point out that there are healthful and unhealthful UPFs. There are actually many healthful UPFs that reduce risk of disease and tend to have one thing in common: They are derived from plants. Listen to today's episode from Physicians Committee for Responsible Medicine at PCRM.org #vegan #plantbased #plantbasedbriefing #UPFs #MAHA #processedfoods #healthyprocessedfoods #ultraprocessedfoods ================== Original post: https://www.pcrm.org/news/news-releases/doctors-group-praises-american-heart-association-statement-not-all-ultra  ================== Related Episodes: 1076: The Tofu Era Is Upon Us: How This Ancient Protein Is Redefining Clean Eating https://plantbasedbriefing.libsyn.com/1076-the-tofu-era-is-upon-us-how-this-ancient-protein-is-redefining-clean-eating-by-the-vegnews-editors-at-vegnewscom  1020: Dairy: The Ultra-Processed Food Hiding In Plain Sight https://plantbasedbriefing.libsyn.com/1020-dairy-the-ultra-processed-food-hiding-in-plain-sight-by-justin-long-at-switch4goodorg 1018: [Part 1] Is the Nova Score Accurate About Processed Vegan Protein? https://plantbasedbriefing.libsyn.com/1018-part-1-is-the-nova-score-accurate-about-processed-vegan-protein-by-vegnews-editors-at-vegnewscom 1019: [Part 2] Is the Nova Score Accurate About Processed Vegan Protein? https://plantbasedbriefing.libsyn.com/1019-part-2-is-the-nova-score-accurate-about-processed-vegan-protein-by-vegnews-editors-at-vegnewscom 851: Headlines Matter: Topline Takeaways From A Recent Ultra-Processed Food Study Are Wrong And Irresponsible https://plantbasedbriefing.libsyn.com/851-headlines-matter-topline-takeaways-from-a-recent-ultra-processed-food-study-are-wrong-and-irresponsible-by-amy-williams-at-gfiorg 565: Cut the Calorie-Rich-And-Processed Foods (CRAP) https://plantbasedbriefing.libsyn.com/565-cut-the-calorie-rich-and-processed-foods-crap-by-dr-michael-greger-at-nutritionfactsorg 502: Meat and Milk Linked to Colon Cancer, Study Confirms https://plantbasedbriefing.libsyn.com/502-meat-and-milk-linked-to-colon-cancer-study-confirms-by-nicole-axworthy-at-vegnewscom ====================== The Physicians Committee for Responsible Medicine is a non-profit organization founded by Dr. Neal Barnard, combining the clout and expertise of more than 12,000 physicians, dietitians, and scientists and almost 200,000 members worldwide. They're changing the way doctors treat chronic diseases such as diabetes, heart disease, obesity, and cancer - putting prevention over pills,and  empowering patients to take control of their own health. And since 1985, the Physicians Committee has worked tirelessly for alternatives to the use of animals in medical education and research, and for more effective scientific methods. The Physicians Committee is dedicated to saving and improving human and animal lives through plant-based diets and ethical and effective scientific research. ============================== FOLLOW THE SHOW ON: YouTube: https://www.youtube.com/@plantbasedbriefing     Spotify: https://open.spotify.com/show/2GONW0q2EDJMzqhuwuxdCF?si=2a20c247461d4ad7 Apple Podcasts: https://podcasts.apple.com/us/podcast/plant-based-briefing/id1562925866 Your podcast app of choice: https://pod.link/1562925866 Facebook: https://www.facebook.com/PlantBasedBriefing    

For more than 30 years, Dr. Christopher Gardner—Rehnborg Farquhar professor of medicine at Stanford, and nutrition scientist—has studied what to consume and to avoid for optimal health, and how best to motivate individuals to achieve healthy dietary behaviors. He recently completed a two-year term serving on the U.S. Dietary Guidelines Advisory Committee and is the past chair of the American Heart Association's Nutrition Committee.He has conducted and published dozens of human nutrition intervention trials, including trials of Mediterranean, Ketogenic, Vegan, Low-Fat and Low-Carb diets and their effects on cardiometabolic health. He was also the keynote speaker for the 6th Canadian Plant-Based Nutrition Conference this year, where he delved into his “Twin Study”, which was featured in a Netflix docuseries titled “You Are What You Eat: A Twin Experiment.”Dr. Gardner joins the PBC Podcast to bust down some of the comments and criticism around his Twin Study, discuss how he weighs strength of evidence, and misinformation around plant-based meat alternatives. ResourcesInstagramTwitter/XLinkedInWebsiteYou are What You Eat docuseriesTwins Study paperBonus PromotionCheck out University of Guelph's online Plant-Based Nutrition Certificate. Each 4-week course will guide you through essential plant-based topics including nutritional benefits, disease prevention, and environmental impacts. You can also customize your learning with unique courses such as Plant-Based Diets for Athletes and Implementing a Plant-Based Diet at Home. As the first university-level plant-based certificate in Canada, you'll explore current research, learn from leading industry experts, and join a community of like-minded people. Use our exclusive discount code PBC2025 to save 10% on all Plant-Based Nutrition Certificate courses. uoguel.ph/pbn.Support the show

About this Episode Episode 48 of “The 2 View” – Burn Tx, Marijuana & CV Risk, Ocular Syphilis, and HSV 1 & 2 Segment 1 – Thermal Burn Treatment Levin NJ, Erben Y, Li Y, et al. Edited by Muacevic A, Adler JR. A Systematic Review and Meta-Analysis Comparing Burn Healing Outcomes Between Silver Sulfadiazine and Aloe vera. Cureus. 2022;14(10):e30815. Accessed August 11, 2025. https://pmc.ncbi.nlm.nih.gov/articles/PMC9621733/ Aziz Z, Abdul Rasool Hassan B. The effects of honey compared to silver sulfadiazine for the treatment of burns: A systematic review of randomized controlled trials. Burns. 2017;43(1):50-57. Accessed August 11, 2025. https://pubmed.ncbi.nlm.nih.gov/27576926/ Segment 2A – Marijuana and Cardiovascular Risk Mohammadi L, Navabzadeh M, Jimenez-Tellez N, et al. Association of Endothelial Dysfunction With Chronic Marijuana Smoking and THC-Edible Use. JAMA Cardiol. Published online May 28, 2025. doi:10.1001/jamacardio.2025.1399. Accessed August 11, 2025. https://jamanetwork.com/journals/jamacardiology/fullarticle/2834540 Storck W, Elbaz M, Vindis C, et al. Eifling KP, Gaudio FG, Dumke C, et al. Cardiovascular risk associated with the use of cannabis and cannabinoids: a systematic review and meta-analysis. Heart. Published online June 17, 2025. doi:10.1136/heartjnl-2024-325429. Accessed August 11, 2025. https://pubmed.ncbi.nlm.nih.gov/40527600/ Page II RL, Allen LA, Kloner RA, et al. Medical Marijuana, Recreational Cannabis, and Cardiovascular Health: A Scientific Statement From the American Heart Association. Circulation. 2020;142(10);e131-152. https://www.ahajournals.org/doi/full/10.1161/CIR.0000000000000883 Segment 2B – Ocular Syphilis Zhou LR, Kirupaharan N, Birkenstock MK. Incidence and Prevalence of Syphilitic Uveitis and Associated Ocular Complications in the TriNetX Database. Am J Ophthalmol. 2025;277:387-394. https://www.sciencedirect.com/science/article/pii/S0002939425002843 Segment 3 - HSV 1 & 2 Langenberg AGM, Corey L, Ashley RL, et al. A Prospective Study of New Infections with Herpes Simplex Virus Type 1 and Type 2. N Engl J Med. 1999;341:1432-1438. https://www.nejm.org/doi/full/10.1056/nejm199911043411904 Lebrun-Vignes B, Bouzamondo A, Dupuy A, et al. A meta-analysis to assess the efficacy of oral antiviral treatment to prevent genital herpes outbreaks. J Am Acad Dermatol. 2007;57(20):238-246. Recurring Sources Center for Medical Education. http://ccme.org The Proceduralist. http://www.theproceduralist.org The Procedural Pause. https://journals.lww.com/em-news/blog/theproceduralpause/pages/default.aspx The Skeptics Guide to Emergency Medicine. http://www.thesgem.com Be sure to keep tuning in for more great prizes and fun trivia questions! Once you hear the question, please email us your guesses at 2viewcast@gmail.com and tell us who you want to give a shout-out to.

Nutritionist Leyla Muedin reveals the alarming increase in obesity-associated cancers in the United States over the past two decades. Highlighting findings from a recent study presented at the Endocrine Society's annual meeting, Leyla underscores the significant rise in cancer deaths linked to obesity, particularly among women, older adults, Native Americans, and Black Americans. She also explores the complex causes of obesity, including genetics, lifestyle, and environmental factors, and offers insights into effective weight management strategies. Additionally, Leyla examines the high rates of heart disease in various U.S. states, emphasizing the importance of lifestyle modifications and public health initiatives to combat cardiovascular diseases.

In this high-yield two part episode, we dive into the evolving world of resuscitation with Dr. David Leon, Assistant Professor of Emergency Medicine and Anesthesia at UC Davis. From the shift in priorities from ABC (Airway-Breathing-Circulation) to CAB (Circulation first) to the practical use of peripheral vasopressors and rapid infusion catheters, this episode breaks down how frontline ED care is adapting to sicker patients, longer ICU boarding times, and limited resources. Tune in for insights on advanced access strategies, pre-hospital blood products, and why old tools, like whole blood and vasopressin, are making a powerful comeback. What do you think of Dr. Leon's tips? Are you using these tools in your practice? We'd love to hear from you. Share them with us on social media @empulsepodcast or connect with us on ucdavisem.com Hosts: Dr. Julia Magaña, Professor of Pediatric Emergency Medicine at UC Davis Dr. Sarah Medeiros, Professor of Emergency Medicine at UC Davis Guest: Dr. David Leon, Assistant Professor of Emergency Medicine and Anesthesia at UC Davis Resources: American Heart Association (AHA) Algorithms Perman SM, Elmer J, Maciel CB, Uzendu A, May T, Mumma BE, Bartos JA, Rodriguez AJ, Kurz MC, Panchal AR, Rittenberger JC; American Heart Association. 2023 American Heart Association Focused Update on Adult Advanced Cardiovascular Life Support: An Update to the American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2024 Jan 30;149(5):e254-e273. doi: 10.1161/CIR.0000000000001194. Epub 2023 Dec 18. PMID: 38108133. **** Thank you to the UC Davis Department of Emergency Medicine for supporting this podcast and to Orlando Magaña at OM Productions for audio production services.

What would you do if someone’s life suddenly depended on you? Meet four everyday people who stepped into crisis and saved a life. A 9-year-old girl calls 911 when her father collapses. A teen athlete performs CPR on a rival player. A librarian administers Narcan to a woman outside the library. A teacher stops the bleeding, and later wrestles with his need to be called a hero. Resources: Stop the Bleed by The American College of Surgeons: training resources, including online classes The American Red Cross: training options, including CPR, first aid, AED, and water safety classes The American Heart Association: training resources, including CPR, first aid, and AED classes Suggested episodes: 911, What’s Your Emergency? Tales From Dispatch More than a bodyguard: Will Geddes on the art of protection GUESTS: Analia and Alex Sinanis: a 9-year-old daughter and her father from New Haven, CT. When Alex, a police officer in North Haven, experienced a medical emergency, Analia called 911 and helped save his life Magnus Miller: an 18-year-old recent high school graduate, who stepped in to help after a fellow athlete went into cardiac arrest during a basketball game in Oklahoma Caroline Mandaro: a Youth Services Librarian in Centereach, NY. She administered Narcan to a woman who had overdosed Patrick O’Connor: a teacher and writer from Massachusetts. He used his Stop the Bleed training after a neighbor's artery was severed by glass Support the show: https://www.wnpr.org/donateSee omnystudio.com/listener for privacy information.

CHI-SVM hospital in Morrilton earns honors from American Heart Association; Bargains Galore on Highway 64 to be held first full weekend in August; Westrock Coffee opens additional facility in Conway; today's the deadline to sign up for Leadership Conway County 2025-26 class; 2025 high school football season starts in five weeks; we visit with Kevin Van Pelt of the Conway County Extension Service.

Omega-3 fatty acids have long been lauded for heart health benefits. Yet, emerging research now points to an even more profound impact, directly on our most complex organ: the brain. Today, we delve into the critical, often misunderstood, role of omega-3s in cognitive function, mental well-being, and even the prevention of neurodegenerative conditions like dementia. We are joined by Dr. Bill Harris, a globally recognised authority in omega-3 fatty acid research. Bill is a Professor at the University of South Dakota and has over 300 peer-reviewed publications. His foundational work includes pioneering studies on fish oil in the 1980s and shaping American Heart Association scientific statements. In this episode, Dr. Harris - along with ZOE's Chief Scientist Professor Sarah Berry - illuminate why most individuals may be operating with suboptimal omega-3 levels, and the tangible implications this has for mood regulation, anxiety, and long-term brain resilience. We navigate nuances between omega-3 types like EPA and DHA, debunk common misconceptions surrounding plant-based sources and mercury content in fish, and explore the precise methods for assessing and improving your own "Omega-3 Index." Unwrap the truth about your food

Suzette Ford-Duffus, Head of Meeting and Events at Taco Bell joins Amanda Ma, CEO & Founder at Innovate Marketing Group, to discuss Taco Bell's bold experiential strategy, viral brand moments, and how events can drive real cultural and business impact.About the guest:Suzette is an award-winning, innovative leader with 20+ years' experience in experiential events and conferences. She spearheads the creative development and implementation of large-scale, complex projects that enhance brand awareness and/or generate franchisee investment. Suzette is fiscally savvy, having managed budgets from $100K to millions of dollars. Her unique professional authenticity inspires teams to excel in all areas.  At Taco Bell, Suzette is responsible for driving strategic planning, project management and event execution for events, with a strong focus on franchisee meetings, incentive trips, team member events and consumer events. A key highlight is executing the first Taco Bell Hotel consumer pop up experience that created fanatical brand love and led to the best sales month in Taco Bell history.  Prior to Taco Bell, Suzette also successfully produced events and managed marketing campaigns for other major brands, including Disney and American Heart Association. These events garnered global interest from media, celebrities, partner organizations, sponsors, board members, staff and fans.   Suzette is based in Orange County, California with her husband and two children. She is a proud graduate of California State University - Fullerton.Follow Suzette in LinkedIn!EventUp is brought to you by Innovate Marketing Group. An award-winning Corporate Event and Experiential Marketing Agency based in Los Angeles, California. Creating Nationwide Immersive Event Experiences to help brands connect with people. To learn more, click here⁠⁠.At Innovate Marketing Group, we've curated a collection of free resources designed to help you elevate your events and marketing efforts. Whether you're planning a company retreat or navigating the latest event trends, our tools, reports, and checklists are here to support your success and keep you at the forefront of innovation. Click here to learn more!Follow us on:LinkedIn⁠⁠⁠⁠EventUp Podcast⁠⁠Instagram

ChatGPT recommends the Mediterranean diet as best for overall health. It groups red meat, sugar, and processed foods together as foods to avoid and recommends plant-based diets as superior. ChatGPT recommends avoiding keto and carnivore diets on a long-term basis. ChatGPT health advice comes from organizations such as the American Heart Association and the American Diabetes Association, which are heavily funded by certain industries and inherently biased. To lower cholesterol, ChatGPT claims you should lower dietary cholesterol, increase unsaturated fats, and replace animal proteins with plant proteins. Plants do not have complete protein, and if you reduce your dietary cholesterol, you could end up low in bile and vitamin D. Cholesterol is a vital component of your cell membranes, hormones, and brain.ChatGPT falsely claims that seed oils are not “that bad” when used in moderation. Balance and moderation allow you to continue eating bad food without worrying about the consequences. If you have a chronic disease, you can not simply “balance” your diet. If you have diabetes, you do not want to spike insulin with carbohydrates. ChatGPT recommends legumes and grains for people with diabetes and small, frequent meals. This advice would continue to spike insulin, and would not help reverse diabetes!When asked about diet and nutrition for people with chronic diseases, ChatGPT ignores powerful ways to drastically improve one's health, such as increasing vitamin D and fasting. It continues to recommend moderation for ultra-processed foods, claiming that it is safe and healthy for 20% of your daily calories to be ultra-processed.Dr. Eric Berg DC Bio:Dr. Berg, age 60, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the author of the best-selling book The Healthy Keto Plan, and is the Director of Dr. Berg Nutritionals. He no longer practices, but focuses on health education through social media.

Optimiza tu LDL Colesterol e interpreta tu analítica o las de tus pacientes hoy, sin fármacos, aplicando estrategias nutricionales y suplementos clave con dosis y ciencia. Accede aquí:https://philhugo.com/producto/ldl-colesterol/  ¡Te espero dentro!Los suplementos be levels mencionados que formulo personalmente: Tu código de descuento: INTERGALACTICOBerberina: https://shop.belevels.com/products/berberine?sca_ref=745165.uf0cpcacla Omega 3: https://belevels.com/products/omega3?sca_ref=745165.uf0cpcaclaTriple Magnesio: https://belevels.com/products/magnesium?variant=47417739379012.uf0cpcacla Dosis y los demás explicados en el curso de Control Absoluto del LDL Colesterol.¿Sigues una dieta cetogénica estricta y tu LDL se ha disparado a niveles que asustarían a cualquier médico? No estás solo. En este episodio, desentrañamos la fisiología del Lean Mass Hyperresponder (LMHR): un perfil metabólico donde el colesterol LDL se eleva no por enfermedad, sino por eficiencia energética. Aprende cómo tu hígado, en ausencia de glucosa, convierte grasa en combustible a través de VLDL y LDL. Descubre por qué un LDL de 300 mg/dL puede ser normal si tu HDL está alto, tus triglicéridos bajos y tu inflamación es cero. Estudio a estudio, desmonto los miedos injustificados y propone estrategias clínicas reales para modular tu LDL si es necesario, desde el aumento de carbohidratos limpios hasta la optimización tiroidea y muscular. Este episodio no es para quien se conforma con los rangos de laboratorio estándar. Es para quien quiere entender su cuerpo desde la lógica metabólica y tomar decisiones con ciencia, no con miedo.ReferenciasApoB es biomarcador y posible diana terapéutica cardiovascular. Behbodikhah, Jennifer et al. “Apolipoprotein B and Cardiovascular Disease: Biomarker and Potential Therapeutic Target.” Metabolites vol. 11,10 690. 8 Oct. 2021LDL sube mucho en "lean mass hyper-responders" con dieta baja en carbohidratos. Norwitz, Nicholas G et al. “Elevated LDL Cholesterol with a Carbohydrate-Restricted Diet: Evidence for a "Lean Mass Hyper-Responder" Phenotype.” Current developments in nutrition vol. 6,1 nzab144. 30 Nov. 2021Marcadores tiroideos y composición corporal predicen cambios en LDL con dieta cetogénica. Cooper, Isabella D et al. “Thyroid markers and body composition predict LDL-cholesterol change in lean healthy women on a ketogenic diet: experimental support for the lipid energy model.” Frontiers in endocrinology vol. 14 1326768. 21 Dec. 2023Omega-3 mejora dislipidemia en relación dosis-respuesta. Wang, Tianjiao et al. “Association Between Omega-3 Fatty Acid Intake and Dyslipidemia: A Continuous Dose-Response Meta-Analysis of Randomized Controlled Trials.” Journal of the American Heart Association vol. 12,11 (2023): e029512.Omega-3 de prescripción tiene efectos lipídicos beneficiosos. Bays, Harold E et al. “Prescription omega-3 fatty acids and their lipid effects: physiologic mechanisms of action and clinical implications.” Expert review of cardiovascular therapy vol. 6,3 (2008): 391-409La berberina reduce lípidos, sola o combinada. Koppen, Laura M et al. “Efficacy of Berberine Alone and in Combination for the Treatment of Hyperlipidemia: A Systematic Review.” Journal of evidence-based complementary & alternative medicine vol. 22,4 (2017): 956-968.Niacina baja lipoproteína(a) según fenotipo de apo(a). Artemeva, N V et al. “Lowering of lipoprotein(a) level under niacin treatment is dependent on apolipoprotein(a) phenotype.” Atherosclerosis. Supplements vol. 18 (2015): 53-8

Jennie Garth is best known to Gen-Xers for her iconic role playing Kelly Taylor on the megahit television series Beverly Hills 90210.  Fans of the show may remember Kelly's pivotal “I Choose Me” episode (airing thirty years ago this past May) when she stood between dreamboats Brandon and Dylan and declared that she was choosing herself.  Jennie shaped an entire era of pop culture, and now, at fifty-two, she is embracing an incredible new chapter of life—one filled with bold conversations about aging, empowerment, self-love, and the beautiful messiness of midlife. Through her thought-provoking “I Choose Me” podcast and a forthcoming memoir of the same name, Jennie is using her platform to champion other women over fifty by challenging outdated narratives around aging and sparking empowering conversations. Today, Jennie, Jen and Amy talk about what choosing yourself looks like on a normal day, and what it means to be graduate beyond our growing family years into a more independent space where a new age of self-discovery is possible because, as Jennie reminds us, choosing “you” isn't selfish—it's the most powerful act of self-respect. Thought-provoking Quotes: “It was through my conversations with fans, whether it was on social media. or at autograph events that I kept hearing, ‘I didn't know I could choose me until Kelly Taylor told me it was an option.'” – Jennie Garth “If I had gone to college and lived a normal life, then I would have learned things that I didn't actually end up learning until I was in my forties and fifties. So now I'm just searching like, ‘What did I miss and how can I be better? How can I learn more about myself?'” – Jennie Garth “You look around on social media and you see other people's lives and think, ‘My God, they have it all figured out.' And I just never felt like that personally.” – Jennie Garth “Loving yourself is a journey and it's imperative to your wellbeing.” – Jennie Garth “I don't want to please people by being what they want me to be or fitting into this character's shoes. I love acting and I'll never not love acting. But I had to take the bull by the horns and take control of my life.” – Jennie Garth “Competition amongst women was real. It was just part of the  world I grew up in. I had to be better than the next girl. What a waste of so much precious time and energy. I used to be intimidated by other women's success or knowledge or position. I kick myself for all the years of lost opportunity of that kind of camaraderie and connection with other women. I feel it so strongly now. It's something that can never be quieted again,” – Jennie Garth Resources Mentioned in This Episode: Beverly Hills, 90210 (1990-2000) - https://www.imdb.com/title/tt0098749/ Tori Spelling - https://www.instagram.com/p/DKAANczu145/?hl=en I Choose Me Women's Summit 2025 - https://jenniegarth.com/pages/i-choose-me-movement I Choose Me: Chasing Joy, Finding Purpose & Embracing Reinvention by Jennie Garth - https://amzn.to/44d8eMM Me by Jennie Garth QVC Collection - https://jenniegarth.com/pages/me-by-jennie-garth Feeding America - https://www.feedingamerica.org/partners/entertainment-council/jennie-garth American Heart Association - https://www.heart.org/en/health-topics/at-the-heart-of-it-with-nancy-brown/the-power-of-positivity-with-jennie-garth Guest's Links: Website - https://jenniegarth.com/ Instagram - https://www.instagram.com/jenniegarth/ Twitter - https://x.com/jenniegarth Facebook - https://www.facebook.com/jenniegarth TikTok - https://www.tiktok.com/@officialjenniegarth Podcast - https://jenniegarth.com/pages/i-choose-me-podcast Connect with Jen!Jen's Website - https://jenhatmaker.com/ Jen's Instagram - https://instagram.com/jenhatmakerJen's Twitter - https://twitter.com/jenHatmaker/ Jen's Facebook - https://facebook.com/jenhatmakerJen's YouTube - https://www.youtube.com/user/JenHatmaker The For the Love Podcast is presented by Audacy.  To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices

Send us a message!In this episode Dana interviews Award winning food and travel journalist, speaker, author, nutrition communications consultant, television personality and registered dietitian nutritionist, Carolyn O'Neil, MS, RDN.Carolyn shares how she found her love of nutrition (and writing) and started working in nutrition media. Carolyn's newly launched podcast is Watch What You Eat with Carolyn O'Neil. Find her on Instagram at @carolynoneil More about our guest:Carolyn writes about food, nutrition, travel and healthy lifestyles for numerous publications including VIE Magazine, OLTRE Magazine, Atlanta Homes & Lifestyles Magazine, Southern Living Magazine and Food & Wine Magazines. She is on the Nutrition Review Board for Southern Living Magazine and Forbes Health.Carolyn is a member of the invite-only Google Food Lab, an international group of thought leaders in all areas of food from farming to finance. She served on Delta Air Lines Culinary Council as a nutrition consultant to help update and guide the airline's inflight menu planning for special meals and wellness initiatives.As a media spokesperson, Carolyn has worked with multiply leading brands including Nestle, The Wonderful Company, Quaker, Sunsweet, Danone, ConAgra and many others. Carolyn has been a professor of nutrition science and nutrition communication for Florida State University's London Study Centre and professor of journalism for Emory University in Atlanta.She is a contributor to NBC Atlanta & Company and can be seen as “The Lady of the Refrigerator” on Alton Brown's Good Eats on Food Network. Carolyn is the author of Southern Living's best selling The Slim Down South Cookbook and co-author of The Dish on Eating Healthy and Being Fabulous winner at the World Food Media awards.A pioneer in food television, Carolyn launched and led CNN's coverage of food andnutrition for nearly 20 years as anchor and executive producer of CNN On The Menu and was senior correspondent and anchor for CNN's Travel Now program. She's earned two James Beard Foundation Awards for excellence in broadcast food journalism and is a member of the James Beard Foundation's Who's Who in American Food and Beverage. She has also been honored by the National Restaurant Association, the American Heart Association, the American Society for Nutrition and the Academy of Nutrition and Dietetics for her pioneering work in nutrition communications. Her master's degree in nutrition is from Boston University and undergraduate degree in Foods and Nutrition is from Florida State University. Carolyn lives in Atlanta.

Remember that mustache guy who made you spit out your coffee laughing about beef jerky and HOA disputes? Scotty K returns to the podcast where it all began, bringing us along for the wild ride his life has become since our last conversation.From quitting his firefighter job to reaching nearly 4 million TikTok followers in just over a year, Scotty's transformation has been nothing short of extraordinary. But what stands out isn't the follower count—it's what he's done with it. Through marathon livestreams and ruck marches, he's raised over $143,000 for the American Heart Association. His fitness company now employs 25 full-time coaches (including actual doctors) and helps clients like Eric, who at 800 pounds is working toward standing up for the first time in four years.The conversation takes us through Scotty's adventures across America, from being recognized everywhere he goes to jumping out of planes with Army paratroopers. We get the inside scoop on his upcoming apparel brand, Fault Line Apparel, designed to combat toxic masculinity with a "brutalist survivalist" aesthetic. There's also his unexpected partnership with Bethesda, where he'll be cosplaying as an NCR Ranger from Fallout at gaming conventions.What makes this episode special is the genuine reflection on what it means to suddenly have influence. As Scotty puts it, "I didn't anticipate the impact some of my videos would have on people." Whether he's making viewers laugh with outlandish food reviews or moving them to tears with vulnerable moments, his authenticity shines through. Because as he learned in therapy: "I don't deserve it, but I belong here."Ready to laugh, be inspired, and maybe shed a tear? Press play and discover what happens when a mustached fitness guy decides to weaponize his audience—not for personal gain, but for making the world better, one video at a time. Support the showYou can find us on social media here:Rob TiktokRob InstagramLiam TiktokLiam Instagram

If you ordered a steak at a restaurant are you essentially ordering a heart attack or a nutrient-rich whole food?Few foods spark more debate than red meat. It's been blamed for heart disease, cancer and diabetes, but some people praise it for being high in iron, zinc, vitamin B12 and quality protein. So, if you add red meat to your plate is it helpful or harmful?Whether you eat meat or avoid it, I think you'll find today's conversation cuts through the noise of social media and clears up a lot of confusion in the nutrition space. I wanted to disentangle the obvious issues surrounding environmental concerns of eating animal products from today's discussion, and simply talk through the data as we have it. It's given me a lot to think about when it comes to recommendations for people, as well as how concerned I would be about red meat consumption overall.Today we're chatting with researcher and academic Dr. Kevin Maki, PhD, who specialises in clinical studies on nutrition, metabolism, and chronic disease risk factors. He's also an Adjunct Professor at Indiana University School of Public Health, a Master and Past President of the National Lipid Association, and a Fellow of the American Heart Association and The Obesity Society. Dr. Maki has participated in over 300 clinical trials and published more than 250 scientific papers, books and book chapters.You're going to learn about:Whether red meat is actually unhealthier than poultryWhat red meat really does to your cholesterol, your blood pressure and your long-term health riskWhether red meat is a source of unhealthy fatsTypes of red meat and which ones are less healthy than othersHow much red meat you can safely consumeWe also talk about seed oils, plus high protein diets and their relationship to kidney disease, longevity and diabetes risk.The 4 big takeaways I got from this episode were:Moderate amounts (50g per day) of unprocessed lean red meat in the diet is fineDiet quality and the addition of whole unprocessed foods is more importantHigh Protein is very important in middle aged and older adultsBeware of the 4 white poisons: Sugar, Salt, Saturated Fat and refined Starches

Last week, Kennedy announced the U.S. would not renew its $1.2 billion commitment to the global vaccine agency Gavi.The new Advisory Committee on Immunization Practices also met for the first time last week since Kennedy fired and then replaced its members. We talk about the outlook for U.S. vaccine policy both at home and abroad.Then, we switch gears to discuss the link between menopause and an increased risk of cardiovascular illness.Heart disease is the leading cause of death in women in the U.S. according to the American Heart Association. We discuss the link between heart health and menopause. Want to support 1A? Give to your local public radio station and subscribe to this podcast. Have questions? Connect with us. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

1. Artificial food dyesThere is no benefit to having toxic, artificial food coloring in our foods. The Delaney Clause prohibited the use of any food additives shown to induce cancer in humans or animals; however, in 1996, the Food Quality Protection Act effectively reversed this clause, allowing these chemicals back into the food supply. 2. The SNAP ProgramRFK Jr. is actively working to eliminate junk foods from the SNAP program. He is receiving a lot of pushback, even from unlikely sources, like the American Heart Association. 3. Titanium dioxide This ingredient is banned in France for causing DNA damage! It can enter the brain and has been identified as a carcinogen. RFK Jr. is actively working to remove this ingredient from the food supply.4. Brominated vegetable oil This flame retardant has nothing to do with vegetables! Although it's still used in American soft drinks, BVO has been banned in Europe, Japan, and India. 5. Potassium bromateThis possible carcinogen is used to fluff up dough, yet it's banned in 30 countries, but not in the US. 6. High-fructose corn syrup This corn-derived sweetener can lead to liver damage, a fatty liver, type 2 diabetes, heart disease, and more. Many activists have been working to get this banned or limited in the children's school system for some time.7. Seed oils The average person consumes 25 to 30 percent of their calories from seed oils. They cause inflammation and other toxic effects, and can linger in the body for over a year after consumption. 8. Ultra-processed foods Ultra-processed foods contain synthetic starches, synthetic sugar, and seed oils. RFK Jr. aims to remove these foods from children's lunches, hospitals, and assisted living homes. 9. Artificial sweeteners Sugar alcohols are made by fermenting natural ingredients, while artificial sweeteners use chemicals like petroleum. These sweeteners cause significant damage, including an alteration of your gut microbes and cancer.10. GRAS The GRAS (generally recognized as safe) loophole allows industries to do their own testing to determine if a product is safe. Dr. Eric Berg DC Bio:Dr. Berg, age 60, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the author of the best-selling book The Healthy Keto Plan, and is the Director of Dr. Berg Nutritionals. He no longer practices, but focuses on health education through social media.

Dr. Hoffman continues his conversation with Dr. Nina Teicholz, a PhD nutritionist, founder of the Nutrition Coalition, and author of "The Big Fat Surprise".

The Protein Paradigm: Redefining Dietary Guidelines with Dr. Nina Teicholz, a PhD nutritionist, founder of the Nutrition Coalition, and author of "The Big Fat Surprise". The discussion focuses on controversies around dietary guidelines, particularly the misrepresentation of low-fat diets and the critical role of protein in optimal health. Dr. Teicholz addresses the flaws in the US Dietary Guidelines, highlights the impact of institutionalized groupthink on nutrition science, and argues for the reassessment of protein recommendations and the demonization of saturated fats. She also examines the challenges and influence of food industry conflicts on public health policies and shares insights on the potential for meaningful reform under the current administration.

What if your blood pressure — even just a little too high — is quietly damaging your brain? What if it's increasing your risk of a heart attack or stroke, without you ever feeling a thing? In this episode, Professor Tim Spector reveals why blood pressure is one of the most overlooked – and most dangerous – health issues today. He explains why “normal for your age” might not be safe at all, why medication alone isn't the full answer, and how small, daily changes could dramatically reduce your risk of serious disease. Can your gut microbes raise your blood pressure? Can a banana be as powerful as a pill? Is beetroot juice really three times more effective than cutting salt? You'll also learn why 80% of the salt we eat isn't from the shaker, how stress and sleep secretly push your pressure up, and what most doctors still miss when treating hypertension. If you've ever been told your blood pressure's “fine” — or never measured it at all — this episode might change the way you think about your future health.

Do you need hours at the gym for it to count? Nope! In today's episode, I'm breaking down exactly how much movement it really takes to support your health… according to science, not social media. Whether you're struggling to stay consistent or just want to know what the bare minimum is (and why it's enough), I've got you covered with today's episode. You'll learn: How much you have to workout for it to “count” If weekend-only workouts can still improve your health What the CDC and NHS say about minimum activity (and how to make it work for you) Simple mindset shifts that make it easier to stay on track (even when life gets busy) All the links: Liao, Dan‐Qing, et al. "Association of Accelerometer‐Derived Physical Activity Pattern With the Risks of All‐Cause, Cardiovascular Disease, and Cancer Death." Journal of the American Heart Association 14.8 (2025): e039225. Sinatra, Stephen T., et al. "Grounding–The universal anti-inflammatory remedy." biomedical journal 46.1 (2023): 11-16. CDC Physical Activity Basics NHS - Physical activity guidelines for adults aged 19 to 64 Want to make movement a habit (without guessing what to do)? Get your first 2 months inside the Movement Mavens® Video Vault for only $9 with code PODNERD www.aewellness.com/podcast - Show notes, links and more. Instagram @hollaformala TikTok @ aewellness Bodywork Starter Guide - learn the 6 places you need to roll right now for quick relief, plus the reason why what you've tried so far has only given you a temporary fix. Download the guide for free now at www.aewellness.com/bodywork 818-396-6501 is the Body Nerd Hotline - how do you build consistency and/or where are you getting stuck? Drop me a line and let me know your body nerd hacks - you might just hear your voice on a future episode!   Today's episode of The Body Nerd Show is brought to you by Movement Mavens™ Therapy Balls—the official mobility tool of the show and the best way to keep your body moving pain-free. Tight hips? Stiff back? Movement Mavens Therapy Balls are designed to mimic the feel of a massage therapist's hands, helping you release tension, improve flexibility, and move better—every single day. Because let's be real—foam rollers are meh, and tennis balls? Not even close. Get the best. Your body deserves it. And right now, you can save 25% on all therapy balls, kits, and workshops with code BODYNERD25. Shop now at www.aewellness.com/shop-now/

Most Americans are eating and drinking far more sugar than is good for us. It's easy to do. Sugar is added to everything from breakfast cereals and flavored coffee creamers to salad dressings and pasta sauces. And all of that sugar can add up. Americans consume an average of 17 teaspoons of sugar a day with some estimates as high as 34 teaspoons a day. That's about three times the daily limit recommended by the American Heart Association.U.S. Health and Human Services Secretary Robert F. Kennedy Jr. recently said, “Sugar is poison,” and recommends that Americans consume “zero” added sugar. So how much is too much? MPR News host Angela Davis talks with a doctor and a dietitian about what sugar does to our bodies and ways to cut back to improve our health.  Guests: Dr. Allison Estrada is an endocrinologist at Hennepin HealthCare.    Alex Larson is a registered dietitian nutritionist based near Duluth.  Subscribe to the MPR News with Angela Davis podcast on: Apple Podcasts, Spotify or RSS.   Use the audio player above to listen to the full conversation.     

 Dr. Laura Catena reacts to AHA's statement on alcohol and cardiac health and the possibility of USDA Dietary Guidelines dropping alcohol consumption guidance.Given the recent news that the USDA may drop the current recommendation of one alcoholic drink per day for women and two alcoholic drinks per day for men in the soon to be released update of the USDA dietary guidelines, and the American Heart Association's new statement that alcohol may have no to little impact or could even be beneficial on heart health, we are fortunate to have just the right person to respond to this and sort it all out for us.We welcome vintner and physician Dr. Laura Catena back to the podcast. With her unique dual background in medicine and winemaking, Catena shares her researched perspective, emphasizing the importance of scientific integrity, the value of moderate wine consumption in historical health data, and the need for ongoing research free from bias. She challenges the absolutist messaging that no amount of alcohol is safe, and urges a more balanced, evidence-based conversation.

Welcome to the Civilian Medical Podcast episode 077   Intro Common Medical Emergencies at Camp Allergic reactions and anaphylaxis (e.g., bee stings, food allergies, poison ivy). Broken bones, sprains, and concussions. Heat exhaustion, dehydration, and sunburn. Drowning or near-drowning incidents. Camp-specific issues (archery injuries, animal bites, etc.). Medical Equipment AED Drugs (depending on the training and medical oversight), such as epi, Benadryl Bandages, wound closure, ice packs, splints Tourniquets- CAT (minimum age? Should we have an extra small option) Electrolytes What kits does MGO sell that would be good for camp staff IROK Kit: Good for medical staff or groups going on all-day excursions Hiking Kit: For smaller groups or individuals (good to send with your teenager to camp) MOM Kit: Lower-risk activities, expecting small cuts.  Boo-boo Kit: Send to camp with younger kids Essential Training for Staff First Aid, CPR (including child-specific CPR), AED, bleeding control training for everyone. Training resources (American Heart Association, Stop the Bleed, Red Cross). EpiPen training and asthma inhaler use. Scenario-based training: role-playing and drills. Establish a helicopter landing zone Policies and Legal  Medical protocols, including when and how to call EMS. Establish a helicopter landing zone Incident documentation and parent communication. Good Samaritan laws and liability protections. Closing Thoughts Recap key takeaways. Assess readiness, think through each camp activity Next Month: Off-grid excursion medical prep?  

You've been told to trust the experts. To eat more grains. To fear fat. But what if the very foundation of our nutrition guidelines was built not on science—but on religion, corporate funding, and government agendas? In this eye-opening solo episode, Nate Palmer breaks down the wild (and true) history behind the food pyramid. From enemas and yogurt colonics at Battle Creek Sanitarium, to Kellogg's anti-sex cereal crusade, to the billions that Big Food and Big Ag poured into shaping what you eat today—this episode is a masterclass in how we got here… and how to escape it. If you've ever wondered why the standard American diet is so broken, this is your moment of clarity. What You'll Learn: Why the food pyramid was never based on health—but on economics and politics The bizarre religious roots of our dietary guidelines (yes, cereal was invented to stop masturbation) How the USDA's dual mission created a massive conflict of interest The real reason fat was demonized—and who profited most from it How corporate donations to organizations like the American Heart Association shaped public perception What you can do today to eat against the pyramid and reclaim your health  Resources & References: Procter & Gamble's $1.7M donation to the American Heart Association McGovern Committee Dietary Goals (1977) Sugar Research Foundation's funded studies to blame fat over sugar (1967) USDA Farm Subsidy Data (1995–2020, via EWG.org) Kellogg and Battle Creek Sanitarium archives Loma Linda University & Seventh-day Adventist dietary influence

You've been told to trust the experts. To eat more grains. To fear fat. But what if the very foundation of our nutrition guidelines was built not on science—but on religion, corporate funding, and government agendas? In this eye-opening solo episode, Nate Palmer breaks down the wild (and true) history behind the food pyramid. From enemas and yogurt colonics at Battle Creek Sanitarium, to Kellogg's anti-sex cereal crusade, to the billions that Big Food and Big Ag poured into shaping what you eat today—this episode is a masterclass in how we got here… and how to escape it. If you've ever wondered why the standard American diet is so broken, this is your moment of clarity. What You'll Learn: Why the food pyramid was never based on health—but on economics and politics The bizarre religious roots of our dietary guidelines (yes, cereal was invented to stop masturbation) How the USDA's dual mission created a massive conflict of interest The real reason fat was demonized—and who profited most from it How corporate donations to organizations like the American Heart Association shaped public perception What you can do today to eat against the pyramid and reclaim your health  Resources & References: Procter & Gamble's $1.7M donation to the American Heart Association McGovern Committee Dietary Goals (1977) Sugar Research Foundation's funded studies to blame fat over sugar (1967) USDA Farm Subsidy Data (1995–2020, via EWG.org) Kellogg and Battle Creek Sanitarium archives Loma Linda University & Seventh-day Adventist dietary influence

In this episode, we discuss the diagnosis and treatment of resistant hypertension, including a newer endothelin receptor antagonist (ERA) called aprocitentan (Tryvio®). Key Concepts The diagnosis of true resistant hypertension is based on requiring more than 3 antihypertensives (ACE inhibitor or ARB + calcium channel blocker + diuretic) to achieve goal BP, ruling out inaccurate BP readings, and ensuring patient adherence to their antihypertensive therapy. Non-pharmacologic therapy (especially dietary sodium restriction), medication adherence, and lifestyle changes are critical to the treatment of resistant hypertension. The preferred 4th line option for most patients with resistant hypertension is spironolactone. After adding spironolactone, additional therapies are based on expert opinion and patient-specific factors. These additional therapies may include beta blockers, alpha-2 agonists, alpha-1 blockers, hydralazine, minoxidil, and aprocitentan. References Carey RM, Calhoun DA, Bakris GL, et al. Resistant Hypertension: Detection, Evaluation, and Management: A Scientific Statement From the American Heart Association. Hypertension. 2018;72(5):e53-e90. doi:10.1161/HYP.0000000000000084 Mancia G, Kreutz R, Brunström M, et al. 2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of Hypertension: Endorsed by the International Society of Hypertension (ISH) and the European Renal Association (ERA). J Hypertens. 2023;41(12):1874-2071. doi:10.1097/HJH.0000000000003480