Podcasts about ldl

Host Dr. Vera Tarman speaks with Daniel Trevor—entrepreneur-turned “citizen scientist” and author of Unholy Trinity: How Carbs, Sugars, and Oils Make Us Fat, Sick, and Addicted, and How to Escape Their Grip. After a near-fatal heart attack, Daniel dove into medical literature, clinician interviews, and self-tracking. He shares the arguments behind his book, why he believes hyperinsulinemia is a “gateway disease,” how diet patterns may influence cardiometabolic risk and cravings, and the testing he advocates so people can “don't guess—test.” We also discuss controversy in nutrition science, harm-reduction ways to experiment with food choices, and how to navigate mixed messages from experts. About our guest Daniel Trevor has founded high-tech companies, worked in anti-aging projects, and spent 20 years as an actor and musician. His health crisis catalyzed a research journey that informed Unholy Trinity. He now writes and speaks about low-carb/keto to carnivore approaches, lab testing, and lifestyle change. What we cover Daniel's pivot from “Mr. Healthy” to heart-attack survivor and researcher Hyperinsulinemia → insulin resistance → cardiometabolic disease (Daniel's “gateway disease” model) Why some people see a rise in LDL on low-carb diets and what advanced lipoprotein testing (e.g., NMR LipoProfile) may reveal “Lean-mass hyper-responder” profile: high LDL with low triglycerides and high HDL—what it means and why it's debated Coronary artery calcium (CAC) scores, soft vs. calcified plaque, and the “CAC paradox” as Daniel understands it Grains, seed oils, and sugar: Daniel's case for their role in appetite, cravings, and disease risk; critique of popular diet guidance Statins, side effects, and absolute risk/benefit as presented by Daniel (and why shared decision-making matters) Practical, harm-reduction steps: food substitutions, lab work, and building a sustainable plan Where Daniel's thinking intersects—and conflicts—with mainstream guidelines, and how listeners can evaluate claims Key takeaways “Don't guess—test.” Daniel urges listeners to use accessible labs and scans (prioritizing a small set if resources are limited) and to pair results with symptoms and function. Protein and structure can reduce chaos. He advocates prioritizing animal protein, minimizing refined carbs/sugars and seed oils, and making like-for-like swaps to lower cravings. Context matters. Individual responses vary (genetics, meds, comorbidities, history with restriction/addiction). Go slow, track, and use support. Hold nuance. Nutrition science evolves; some claims remain contested. Use informed consent and a collaborative care team. The content of our show is educational only. It does not supplement or supersede your healthcare provider's professional relationship and direction. Always seek the advice of your physician or other qualified mental health providers with any questions you may have regarding a medical condition, substance use disorder, or mental health concern.

How do I keep my LDL low enough without compromising my brain and my liver?I read that fish oil can raise LDL cholesterol. Is this true?A questionable case study on pycnogenol

See all the Healthcasts at https://www.biobalancehealth.com/healthcast-blog As the founder and Medical Director of BioBalance® Health, an anti-aging longevity practice for 23 years, I have long sought a blood test that serves as a reliable indicator of aging and disease risk. Identifying those at highest risk allows me to better motivate patients to follow my treatment plan and pursue a longer, healthier life. For people who test negative, I would reassure them they are doing well and encourage them to maintain healthy habits. Over time, I assessed common medical tests that many doctors use to steer patients toward certain treatments that do not reduce pain and may shorten life. I examined the actual risk of death and illness through clinical evaluations and credible, though less publicized, research studies. Here is what I found: Elevated blood lipids are not reliably predictive of vascular plaque. In my experience, both high and low cholesterol patients show similar rates of plaque in Cardiac Calcium Scans. Despite this, primary care physicians often prescribe statins, which may be unnecessary for many. Statins were not initially tested on women, who tend to experience more severe side effects such as cognitive impairment, muscle breakdown, and fatigue, likely because these drugs impact mitochondrial function—the cell's energy source. BMI has long been used to assess whether someone is at a healthy or risky weight, but it is often inaccurate. It overlooks individuals with low muscle and high fat, while labeling muscular people as overweight. As a result, BMI is being replaced by body composition measurements.   Recently, body composition analysis using InBody has become more common than BMI for evaluating patient health, frailty, and muscle mass. Measurements of visceral fat and body composition are considered indicators of current health status. BMI is a straightforward calculation that only uses height and weight, whereas body composition includes assessments of visceral fat and percent body fat. Only one weight- and height-based test directly relates to health status. High muscle mass indicates health, while excess visceral fat signals risk, and normal body fat percentage reflects current—but not future—health. Since body composition can shift over time, it is a useful measure of present health but does not reliably predict longevity and is just one aspect of overall health. Several blood tests can indicate current health, such as fasting blood sugar, HbA1c, IGF-1, and fasting insulin. For assessing future health risks and existing damage, HS-CRP (high-sensitivity C-reactive protein) is crucial, as it measures inflammation—a major factor in unhealthy aging and reduced longevity, especially when levels exceed 3.0. An article in Life Extension (July 2025) refers to persistently high CRP as “inflammaging.”   The Truth About Aging and Inflammation? Temporary spikes in HS-CRP from infections or surgeries usually do not cause lasting issues unless inflammation persists. Chronically high HS-CRP levels (>3) are linked to various age-related diseases, such as obesity, arteriosclerosis, autoimmune disorders, poor dental hygiene, and other conditions that reduce health and lifespan. We now can measure “inflammaging” with HS-CRP blood test.  This test indicates increased risk of heart disease, cancer, stroke, dementia, autoimmune disease, and other degenerative diseases.” A review of studies with more than 400,000 participants revealed that people with a High HS-CRP had 75% increased risk of all-cause mortality compared to people with a low HS-CRP. These studies found that HS-CRP may be a more reliable predictor of heart attack and stroke, than LDL cholesterol! HS-CRP may predict age-related diseases because chronic inflammation leads to issues such as arterial plaque and Alzheimer's. Although white blood cells fight infection, their persistent activity can damage healthy tissue and accelerate age-related conditions. The changes that you can make to decrease inflammation, Inflammaging, include: Fat loss to ideal weight Low inflammatory mediterranean diet Omega 3 oil supplements or in food Daily exercise Probiotics Quercetin supplement Treat joints that are damaged (inflammation is increased with injured joints) At least 3 cups of coffee per day Less than 4 oz of alcohol a day No sugar in the diet ***Replacing hormones to the levels of a young man or women with non-oral hormones, pellet testosterone for men and both testosterone and estradiol for women.   BioBalance® Health assesses new information through medical studies and bases treatments on knowledge of human physiology and the aging processes. No single test can determine if you are aging well, but HS-CRP is a better indicator than cholesterol or BMI. At BioBalance®, we've tested HS-CRP for 20 years and developed treatments to address inflammaging. Citation: Life Extension –July 2025

Your thyroid might be quietly steering more than just your metabolism—it could be influencing your cholesterol levels, heart health, and even stroke risk. In this episode, we break down the hidden ways hypothyroidism and Hashimoto's can affect your cardiovascular system.From subtle shifts in LDL and HDL cholesterol to the real impact of untreated thyroid disease on heart disease and stroke risk, we explore what the numbers might be telling you. And if you've ever wondered whether thyroid medication can actually protect your heart, we've got the answers.Whether you're navigating high cholesterol, concerned about heart health, or just curious about the thyroid-heart connection, this conversation gives you the clarity—and action steps—you need.

Dr. Jeff Graham sits down with Dr. Damon Forbes to explore the emerging concept of “lean mass hyper-responders”— fit, low-carb individuals who present with unusually high LDL levels. They unpack the physiology behind this pattern, discuss how it differs from familial hypercholesterolemia, and review new data on cardiovascular risk. The conversation offers a nuanced look at how metabolism, diet, and lipid transport intersect in precision medicine.

What happens when a dietitian and a PA sit down to talk about heart disease—from both sides of the exam room?In this episode, Colleen brings together two heart health experts: Michelle Routhenstein, MS, RD, CDCES, a cardiovascular dietitian known for her evidence-based prevention strategies, and Josh Wageman, PA-C, PhD, a clinical lipid specialist who's spent his career studying cholesterol disturbances and Alzheimer's.Together, they tackle one of medicine's most common (and confusing) topics—heart health. You'll hear how each expert thinks, what they prioritize, and how they talk with patients who are juggling elevated LDL, inflammation, insulin resistance, or menopause-related changes. By the end, you'll see how bridging nutrition and medicine leads to smarter, more patient-centered care—because this is how the healthcare team should work anyway. Resources:Episode 38 | Love Your Heart with MichelleEpisode 111 | HDL Good, LDL Bad with JoshEpisode 117 | The Best Diet to Lower Cholesterol with JoshConnect with MichelleBuy Josh's BookAny Questions? Send Me a MessageSupport the showConnect with Colleen:InstagramLinkedInSign up for my FREE Newsletter - Nutrition hot-topics delivered to your inbox each week. Disclaimer: This podcast is a collection of ideas, strategies, and opinions of the author(s). Its goal is to provide useful information on each of the topics shared within. It is not intended to provide medical, health, or professional consultation or to diagnosis-specific weight or feeding challenges. The author(s) advises the reader to always consult with appropriate health, medical, and professional consultants for support for individual children and family situations. The author(s) do not take responsibility for the personal or other risks, loss, or liability incurred as a direct or indirect consequence of the application or use of information provided. All opinions stated in this podcast are my own and do not reflect the opinions of my employer.

A Fortune 250 company in Des Moines, Iowa transformed employee health through a whole-food, plant-based lifestyle.    Discover how Gretchen Barris teamed up with PCRM and Dr. Jim Loomis to launch a 16-week wellness program at Principal Financial that helped 240 participants dramatically lower cholesterol, reverse prediabetes, lose weight, and boost energy — all for just $108 per person.   Chuck Carroll sits down with Jean McGinnis and participants like Malcolm & Suzanne Showalter who conquered migraines, reversed heart disease risk, and experienced newfound vitality. Learn how this evidence-based approach from the Barnard Medical Center and PCRM is revolutionizing corporate wellness — even in the heart of the Midwest!   What You'll Learn in This Episode - How a Fortune 250 company implemented a plant-based program on a small budget - The average 23% LDL reduction and 18% A1C improvement among participants - Why employees reported better sleep, focus, and mental health - The difference between “health care” and “sick care,” explained by Dr. Loomis - How to bring programs like this to your own workplace  

Can strength training, sprinting, and nutrition truly transform women's hormones, metabolism, and longevity? In this episode, Dr. Stephanie Estima — chiropractor, women's health expert, and founder of The Estima Method — breaks down the science of female physiology, muscle, and midlife health. We cover why walking isn't enough, how hormones shape muscle and bone, and why protein and strength training are essential “medicine” for women over 35. Expect myth-busting, practical tools, and empowering insights to help you train and live in sync with your biology. About Dr. Stephanie Estima: Dr. Estima began her career in chiropractic care, where she developed a deep interest in neuroscience, biomechanics, and the body's connection between movement and the brain. After noticing how differently men and women respond to the same health strategies, she became passionate about helping women navigate hormones, metabolism, and midlife health. Where to find Dr. Estima: Instagram: @dr.stephanie.estima Website: https://drstephanieestima.com *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Function Health: Visit https://functionhealth.com/louisa or use gift code NEURO100 at sign-up to own your health. Ketone IQ: Go to https://www.ketone.com/NEURO for 30% OFF your subscription order PUORI: Go to https://puori.com/NEURO and use the code NEURO at checkout for 20% off. AquaTru: Go to https://AquaTru.com now for 20% off (your purifier) using promo code NEURO. AquaTru even comes with a 30-day best-tasting water guarantee. Caraway: Visit https://Carawayhome.com/neuro and take an additional 10% off your next purchase. Jones Road Beauty:  Head to https://Jonesroadbeauty.com and use code NEURO at checkout. *** I'm Louisa Nicola — clinical neuroscientist — Alzheimer's prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer's risk — and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Topics discussed: 00:00 – Intro 03:14 – Reassessing Hormone Therapy in 2025 04:24 – The Rise of HRT & Social Media Awareness 05:37 – Balancing the Conversation: HRT Pros & Cons 06:42 – Lifestyle Levers That Matter More 08:05 – Why Walking Isn't Enough Exercise 10:59 – Muscle Quality & Metabolism Explained 12:29 – Type 1 vs. Type 2 Muscle Fibers 16:25 – Glucose, Muscle, and Longevity18:07 – Bone Health & Estrogen 20:33 – The Power of Impact Training 22:28 – How to Build a “Prescription for Health” 24:06 – The Zone 2 Misconception 26:29 – Progressive Overload & The “Weighted Vest” Myth 27:45 – Sample Lower-Body Workout Blueprint 34:03 – Learning Proper Squat Mechanics 35:28 – The Power of Deadlifts & Hip Hinge Movements 36:46 – Glute Bridges & Unilateral Training 38:35 – Nutrition & Midlife Metabolism 39:47 – How Hormones Change Body Composition 42:06 – Sleep, Insulin, and the Estrogen Cascade 43:59 – Strength Training as Hormone Therapy 45:06 – LDL & Visceral Fat Connection 46:04 – Fasting & Female Metabolism 47:17 – Why Aggressive Fasting Backfires for Women 50:53 – The Dark Side of Fasting Culture 53:22 – Practical Guidelines for Eating Windows 54:03 – Under-Fueling & Protein Deficiency in Women 55:09 – Appetite, GLP-1 Drugs & Metabolic Health Learn more about your ad choices. Visit megaphone.fm/adchoices

This week, Dr. Joel Kahn explores three advanced methods for cleansing the blood. He begins with apheresis, a medical technique that removes LDL cholesterol and Lipoprotein(a), and discusses new developments in access to this life-saving therapy. Dr. Kahn also breaks down two emerging treatments gaining popularity—EBOO (Extracorporeal Blood Oxygenation and Ozonation) and TPE (Therapeutic Plasma Exchange)—and how they may play a role in improving cardiovascular health. In the second half, Dr. Kahn turns to the topic of cholesterol-lowering therapies like statins, emphasizing how long-term use and individualized risk assessment matter more than online debates suggest. He highlights tools such as the Mayo Clinic Statin Decision Aid, PREVENT calculator, and Astro-CHARM calculator to help patients and practitioners make informed decisions.  Thanks to the Fresh Pressed Olive Oil Club for sponsoring this episode. Visit getfreshdrkahn.com for a special offer.

A meta-analysis of low-carb diets for diabetes remission found little to no effect at 12 months, clinically important harms to quality of life, and the deal-killer––an increase in LDL cholesterol.

Heart disease is still the number one killer in the U.S.—but are we even looking at the right markers to prevent it? In this eye-opening episode, Shana sits down with Dr. Urban Kiernan, founder and CEO of iMetabolic Biopharma Corporation, to break down what your lipid panel actually means, why total cholesterol and LDL often distract from the real risks, and how insulin resistance plays a central role in heart disease—especially during menopause. Dr. Kiernan shares how his biotech company is leveraging AI, protein therapy, and root-cause science to transform how we prevent and treat metabolic disease—and why most conventional approaches miss the mark entirely. If you've ever been confused by your labs, put on statins without a full explanation, or wondered why we're still seeing record rates of heart attacks and strokes, this conversation will bring clarity and direction.

Can you really lower cholesterol with food? Dr. Michael Greger joins Chuck Carroll on The Exam Room Podcast to reveal the simple, science-backed foods and spices that can drive LDL cholesterol down—without drugs or side effects. Discover how everyday choices can protect your heart and add years to your life.   What You'll Learn in This Episode:   - Why the Standard American Diet is now the #1 cause of death in the U.S. - The truth about statins: small benefit, real risks. - How plant-based eating can reverse heart disease. - Foods that raise cholesterol: meat, dairy, eggs, coconut & palm oils. - The top foods and spices proven to lower LDL include black soybeans, apples, and garlic powder. - Why olive oil raises cholesterol on a vegan diet. - Green tea and mushrooms: health boosters, but not major LDL-reducers. - Practical tips: even one small daily change makes a big difference.  

Send us a textThe surprising link between oral bacteria and heart disease.Episode Summary: Dr. Pekka Karhunen explains the connection between oral bacteria, cholesterol, and cardiovascular disease, discussing how oxidized LDL cholesterol triggers inflammation in arteries, how bacteria from the mouth can infiltrate arterial plaques to form biofilms, and the implications for heart disease prevention through lifestyle changes like better oral hygiene.About the guest: Pekka Karhunen, MD, PhD is a medical doctor and forensic pathologist with decades of experience, specializing in cardiovascular diseases. He has created a unique biobank of coronary arteries from over 10,000 autopsies conducted in Finland. His research focuses on the role of bacteria in atherosclerosis, particularly through studying coronary artery plaques.Discussion Points:Cholesterol is essential for life, but oxidized low-density lipoprotein (LDL) cholesterol is seen as a foreign substance by the immune system, leading to chronic inflammation in coronary arteries.Macrophages ingest oxidized LDL, turning into dysfunctional foam cells that contribute to plaque buildup, known as atheromas, in arteries.Plaque rupture, potentially caused by increased pressure from cholesterol accumulation or hemorrhage within the plaque, can trigger heart attacks.Bacteria, especially from the mouth, can enter arterial plaques via bacteremia (e.g., from dental procedures) and form biofilms, evading immune detection.Biofilms in plaques, made of extracellular matrix like polysaccharides, protect bacteria and may contribute to plaque instability or calcification over time.Poor oral hygiene is linked to higher cardiovascular disease risk, as bacteria from dental infections can enter plaques, suggesting dental care as a preventive measure.Karhunen's research found oral bacteria, like Viridans streptococci, in coronary plaques, with unpublished data also detecting gut and skin bacteria, indicating diverse bacterial involvement.Related content:M&M 247: Cholesterol: Immune Benefits, Heart Health, Statins & Research Malpractice | Uffe Ravnskov*Not medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

Harvard MD/PhD Nick Norwitz reversed ulcerative colitis, lowered cholesterol with Oreos, and now exposes the cracks in modern medicine. This episode is a masterclass in metabolic rebellion and curiosity.Join the Kiltz Health Certification Course here: 50% DISCOUNT until 10/8/2025: https://buy.stripe.com/fZuaEYbJaeCp4Df2OY0480xJoin the Kiltz Mighty Tribe - It's free: https://kiltz-mighty-tribe.mn.co/0:00 – Nick's medical legacy and why he chose medicine 4:12 – Ulcerative colitis diagnosis and desperation-driven healing 8:45 – Ketogenic diet leads to full remission 12:30 – Why modern medicine fails chronic disease patients 16:05 – Incentives, pharma, and the business of healthcare 20:40 – Why RCTs don't reflect real-world healing 25:10 – Nutrition education gaps in med school 30:00 – GLP-1s, statins, and lifestyle vs. pharma 35:45 – Nick's grocery cart: what he actually eats 41:20 – Red meat and cancer myths 46:00 – The Oreo experiment: lowering LDL with cookies 50:30 – Empowering patients to lead their own health journey 54:00 – “Stay Curious”: Nick's mantra and tattoo 58:00 – Where to follow Nick Norwitz and final reflections

Broadcast from KSQD, Santa Cruz on 10-02-2025: Dr. Dawn opens by explaining how blood pressure treatment guidelines have been corrected back to 140/90 after the problematic 2015 SPRINT study temporarily changed recommendations to 120/80. That study used ideal measurement conditions - five minutes of quiet sitting, perfect cuff sizes, compliant patients - creating unrealistic targets that caused elderly patients to faint and break hips. The Veterans Administration and major cardiology organizations now recommend treating to 140/90, with statins only for LDL above 190 or 12% ten-year cardiovascular risk. An emailer asks about claims linking Tylenol to autism. Dr. Dawn thoroughly debunks this, explaining that Swedish studies of 2.5 million children found no association when controlling for sibling comparisons. She notes autism rates remained flat from 1960-1990 despite widespread Tylenol use, then spiked after DSM-4 in 1994 and DSM-5 in 2013 broadened diagnostic criteria. Recall bias skews studies since mothers of autistic children are asked leading questions about past Tylenol use during pregnancy when fever treatment was medically necessary. She discusses RFK Jr.'s mixed positions, comparing him to Isaac Newton who excelled at physics but believed in astrology. While criticizing vaccine misinformation, Dr. Dawn strongly supports RFK's stance on ultra-processed foods. She describes NIH researcher Kevin Hall's studies showing people consume 500 extra calories daily on ultra-processed diets versus whole foods, even when nutrients are matched. The US produces 15,000 calories per person daily, with the food industry engineered to promote overconsumption through hyper-palatable fat-sugar-salt combinations. A caller asks about Healthcare 4.0 plans for biometric tracking bracelets and digital twins. Dr. Dawn discusses privacy concerns around constant health monitoring and data collection, noting that while early disease detection could be valuable, mandatory participation raises serious civil liberties issues. She acknowledges voluntary research projects like the Million Man Study but emphasizes the importance of consent and protection against unauthorized data access by advertisers or government agencies. An emailer shares research on ultrasound brain stimulation helmets as alternatives to surgical electrode implants. Dr. Dawn explains how 256-element phased ultrasonic arrays can target brain regions like the visual cortex with high precision mechanical perturbation, potentially treating Parkinson's, Alzheimer's, and depression without surgery. The technology remains experimental, requiring MRI guidance, but could become portable and dramatically improve quality of life for neurological conditions currently requiring invasive deep brain stimulation. A caller with adrenal cancer asks about fasting-mimicking diets. Dr. Dawn explains that 14-hour fasting before chemotherapy improves outcomes because healthy cells can downshift metabolism while cancer cells cannot. Cancer cells rely only on glycolysis without mitochondrial function, making them vulnerable during fasting states. She recommends chronotherapy - scheduling treatments during fasting periods - and expresses optimism about new cancer therapies like CAR-T cells and CRISPR technologies. An emailer asks about inulin fiber for fatty liver disease. Dr. Dawn explains how this fiber found in chicory, Jerusalem artichokes, and root vegetables stimulates gut bacteria to break down fructose before it reaches the liver, preventing fructose-induced hepatic lipogenesis. Inulin supplementation protects against fatty liver disease, increases antioxidant production, and helps with obesity by reshaping the gut microbiome to better process dietary sugars.

2025 ACC Scientific Statement on Inflammation & Cardiovascular Disease

Lady runners and endurance athletes, don't let anyone ever tell you we can't lower our cholesterol, balance our hormones, and boost our running performance without extreme diets, endless supplements or prescriptions. Most of the time, there is a (much) better way and it's time we learn some specifics, nuances, and targeted female-specific strategies to try!In this episode of Maximizing Hormones, Physique, and Running Through Perimenopause, Louise Valentine, one of the world's leading health, fitness and performance experts, shares a simple, science-backed roadmap for avid active women and recreational runners age 35+ who are navigating perimenopause and beyond.Louise reveals root cause mechanisms of why LDL cholesterol often spikes as estrogen declines and how outdated advice about cutting out eggs or red meat isn't the full picture. Drawing from over two decades of coaching and research, her own fiercely inspiring health journey, and empowering thousands of individuals over the course of her proven career designing integrative health and fitness interventions, she explains practical steps you can take to improve biomarkers in as little as three months.You'll learn which supplements actually make a difference, how much your specific food choices matter, awareness of how seed oils sneak into your pantry, and why advocating for yourself with doctors matters. You'll get a step-by-step playbook to discuss your labs with your doctor to be fully heard and get the comprehensive effective care you deserve. Most importantly, you'll discover realistic strategies, rooted in cutting-edge female-specific science, that help you feel energized, resilient, and confident in your body.If you're a driven, active woman who's tired of feeling blindsided by midlife changes, this episode is your playbook for thriving with less stress, relentless confidence, and more strength.Link to our FullScript where you can see our curated best supplement picks under "Favorites" & save 20% off the supplements mentioned in today's episode: https://us.fullscript.com/welcome/breakingthroughwellness/store-startLearn & level up with my free nutrition guide and award-winning Badass Breakthrough Academy to thrive through perimenopause with less stress: https://www.breakingthroughwellness.com/ Our affiliate link to check Function Health for comprehensive blood work: https://my.functionhealth.com/signup?code=LVALENTINE11&_saasquatch=LVALENTINE11 Take advantage of our podcast listener discount and save 20% off all of Kion's science-backed clean products: https://www.getkion.com/pages/maximizing Promo code “LOUISE” saves on all future orders!Episode Highlights:(0:000 Intro(3:04) A step-by-step roadmap to lower LDL(7:41) The importance of advanced lipid testing(11:13) A client's success challenging the “only meds” advice(14:56) Louise's personal results lowering biomarkers(19:26) Fueling frameworks that boost natural hormone production(22:42) OuTune in weekly to "Maximizing Hormones, Physique, and Running Through Perimenopause" for our simple female-specific science-based revolution. Let's unlock our best with less stress!I'd love to connect!Instagram

In this episode of The Neuro Experience, I sit down with Dr. Kellyann Niotis—one of the first fellowship-trained preventive neurologists—to reveal how you can protect your brain long before symptoms of Alzheimer's or dementia appear. With Alzheimer's cases expected to triple by 2050, Dr. Niotis explains the difference between dementia types, the real role of genes like ApoE4, and why lifestyle choices may be more powerful than genetics. If you want actionable tools to lower your risk, strengthen your memory, and understand the future of preventive neurology, this conversation delivers science-backed strategies you can start applying today. About Dr. Kellyann Niotis: Dr. Kellyann Niotis is the first fellowship-trained preventive neurologist focused on reducing risk for Alzheimer's, Parkinson's, and Lewy Body Dementia. She launched the nation's first Alzheimer's Prevention Clinic at Weill Cornell and now leads early-detection and brain health research at the Institute for Neurodegenerative Diseases Florida. Her work appears in leading medical journals and has been featured by CNN. *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode:TimelineHead to⁠ http://timeline.com/neuro⁠ to get started. BeamVisit ⁠http://shopbeam.com/TNE⁠ and use code TNE at checkout. Jones Road BeautyHead to ⁠http://Jonesroadbeauty.com⁠ and use code NEURO at checkout. After you purchase, they will ask you where you heard about them. PLEASE support our show and tell them our show sent you. NOCDHead to ⁠http://learn.nocd.com/NEURO⁠ and book a free 15 minute call to get started. Eko HealthGo to ⁠http:/ekohealth.com/NEURO ⁠ for up to $50 off, plus a free chest piece cover.  *** I'm Louisa Nicola — clinical neuroscientist — Alzheimer's prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer's risk — and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ *** Topics discussed: 00:00 – Introduction 01:25 – Preventative neurology 02:23 – Dementia vs. Alzheimer's & Other Types of Dementia 04:08 – What Is Alzheimer's? 05:26 – Clinical Diagnosis: Imaging & Symptoms 07:07 – How Amyloid Disrupts Neural Communication 09:48 – Genetics vs. Lifestyle: Public Misunderstanding 12:02 – Role of Family History & Genetic Risk 14:04 – The ApoE4 Gene Explained15:07 – ApoE Variants 17:08 – ApoE4 and Lipid Transport in the Brain 18:35 – Immune Response & Infection Susceptibility 20:05 – Hormones: Key Role in Brain Health 21:08 – Genotypes & Risk Multipliers 23:01 – ApoE4 Not Always Deterministic: Population Studies 24:15 – Other Genetic Factors Beyond ApoE 25:13 – Biomarkers: Current Use & Limitations 27:13 – Risks of Self-Testing Biomarkers 28:45 – Why Two-Thirds of Patients Are Women 29:46 – Estrogen, Menopause & Neuroprotection 32:07 – Testosterone & Dementia Risk 35:01 – LDL, ApoB & Brain Health Debate 37:01 – Statins & Dementia: Myths vs. Evidence 39:08 – Fear & Misconceptions Around Cholesterol 41:09 – Lipoprotein(a) & Vascular Dementia Risk 44:39 – Brain Vasculature & Hypertension 49:15 – New Alzheimer's Drugs & Risks 55:32 – Why Rates Keep Rising (Lifestyle & Stress) 58:11 – Early Signs 01:00:23 – Tau Protein, Tangles & Neuronal Damage 01:05:49 – Keto vs. Mediterranean 01:07:14 – Personalization & Preference for Mediterranean Diet Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by the⁠⁠ ⁠⁠⁠⁠⁠Primal Tallow Balms⁠⁠⁠⁠⁠.Dr Norwitz ate 720 eggs in 1 month. Here's what happened to his cholesterol. Nick Norwitz, MD, PhD, discusses his groundbreaking experiments on cholesterol, which challenge conventional beliefs about LDL and dietary cholesterol. He emphasizes the importance of understanding the context of cholesterol levels, the role of metabolic health, and the unique phenotype of lean mass hyper-responders. The discussion also covers dietary recommendations, the complexities of LDL and HDL, and the need for comprehensive testing for cardiovascular risk.

Watch every episode ad-free & uncensored on Patreon: https://patreon.com/dannyjones Dr. Paul Saladino is a physician, nutrition specialist & leading expert in the science of the carnivore diet. Nick Norwitz MD PhD is an expert at Harvard in heart health, cholesterol, and obesity. SPONSORS https://whiterabbitenergy.com/?ref=DJP - Use code DJP for 20% off. PAUL SALADINO LINKS @Paulsaladinomd  https://www.instagram.com/paulsaladinomd https://paulsaladinomd.com http://Heartandsoil.co http://Lineageprovisions.com NICK NORWITZ LINKS https://staycuriousmetabolism.com @nicknorwitzMDPhD  https://www.instagram.com/nicknorwitz FOLLOW DANNY JONES https://www.instagram.com/dannyjones https://twitter.com/jonesdanny OUTLINE 00:00 - Flaws in medical research 12:46 - Who's funding nutrition studies 16:06 - Calories don't cause obesity 18:34 - GLP-1 drugs 23:32 - The truth about high LDL levels 36:27 - Is high LDL bad? 46:52 - Western medicine doesn't care about metabolism 54:43 - "Evidence-based" medicine is not the best medicine 01:02:59 - How gut health changes the brain 01:10:08 - Seed oils explained (omega 6 oils) 01:14:25 - History of seed oil consumption 01:27:30 - Linoleic acid's role in the body 01:42:54 - Seed oil studies are historically rigged 02:07:46 - The #1 cause of obesity in America 02:21:02 - Most dangerous ingredient in seed oils 02:30:54 - Blue zones are a myth 02:33:20 - Sunlight vs. blue light 02:50:09 - Are fish actually healthy to eat? 02:57:29 - what causes fat mass in obese people 03:03:22 - Mark Bell's sugar diet 03:11:07 - Is fruit actually unhealthy? 03:25:11 - Curiosity & the ambiguity of nutrition Learn more about your ad choices. Visit podcastchoices.com/adchoices

Broadcast from KSQD, Santa Cruz on 9-25-2025: Dr. Dawn opens with disturbing whistleblower allegations from Patrick Chase about organ transplant corruption. He claims poor patients at Parkland Hospital were systematically denied kidneys that were redirected to wealthier patients at UT Southwestern Medical Center. In 36 documented cases, doctors rejected kidneys as unsuitable for Parkland patients, then transplanted those same organs at the prestigious academic hospital. Chase alleges financial incentives corrupt the entire system, from procurement organizations to waiting list management. She discusses widespread scientific fraud in medical journals, citing research about PLOS journal showing 45 editors facilitated acceptance of fraudulent papers at rates far exceeding chance. These editors represented only 1.3% of reviewers but were responsible for 30% of retracted articles. Paper mills now use AI to generate fake studies with fabricated data, selling authorship to academics seeking publication credits. This undermines evidence-based medicine when treatment guidelines rely on potentially fraudulent research. Dr. Dawn introduces holy basil as a sleep aid beyond melatonin, explaining how its active compound ocimum lowers cortisol and inhibits orexin pathways that promote wakefulness. Unlike melatonin which signals sleep onset, holy basil helps maintain deep sleep by preventing middle-of-night stress spikes. She recommends 500 milligrams of aqueous leaf extract, noting this Ayurvedic herb may be particularly helpful for menopausal women experiencing sleep disruption. She warns about medication-induced osteoporosis, revealing that proton pump inhibitors increase hip fracture risk by 217% after four years of use by impairing calcium absorption and triggering parathyroid hormone release. Antidepressants pose similar risks, with SSRIs increasing fracture risk by 68% and causing women to lose bone 1.6 times faster than non-users. Cancer treatments like androgen deprivation therapy cause severe bone loss, with 81% of long-term users developing osteoporosis. Dr. Dawn challenges cholesterol treatment guidelines, explaining that Quest Labs' recommendation for LDL under 100 contradicts actual medical standards. The Veterans Administration only recommends statins for LDL above 190 plus high cardiovascular risk, or 12% ten-year risk calculated using multiple factors. She criticizes the focus on cosmetic cholesterol numbers while ignoring that high-dose statins increase diabetes risk, which is a greater health threat than elevated LDL alone. A caller describes experiencing severe ear itching followed by facial puffiness after a haircut. Dr. Dawn explains this likely represents a histamine-mediated allergic reaction, possibly triggered by salon products rather than the haircut itself. She advises getting ingredient lists from the salon to identify potential allergens and notes that bilateral symptoms suggest systemic rather than contact allergy. The oral antihistamines the caller took were appropriate treatment. Another caller asks about statin use with LDL of 155, expressing concern about adverse effects. Dr. Dawn recommends calculating ten-year cardiovascular risk rather than focusing solely on LDL numbers. She explains serious statin risks including muscle breakdown and diabetes development, particularly in women. For patients with muscle pain from statins, she suggests CoQ10 supplementation, but discontinuation if symptoms persist to prevent kidney damage from rhabdomyolysis.

  In this episode of The Heart to Heart podcast, host Dr. Mike Hart interviews Alex Leaf, an independent nutritional researcher renowned for debunking nutritional misinformation on social media. The discussion covers topics such as the benefits of collagen for skin health, the potential advantages of ketogenic diets for athletes, and the truth behind various nutrition myths including the effects of soy on testosterone and semen retention. Alex also shares his insights on intermittent fasting, ideal protein intake, and the debate over seed oils. The conversation concludes with their thoughts on cardiovascular health markers and the relevance of particle size in LDL cholesterol.    Alex Leaf is an independent nutritional researcher, scientific communicator, and educator specializing in human health and performance. With a decade of experience translating complex science into actionable insights, Alex rose to prominence as a researcher and writer at Examine.com before joining Ari Whitten's Energy Blueprint. His work spans peer-reviewed publications—including contributions to the ISSN position stand on ketogenic diets—and teaching in the Master's program in Human Nutrition and Functional Medicine at the University of Western States. Follow him here: Website: alexleaf.com Instagram: @AlexJLeaf   Links: IVF and Abstinence Studies Systematic Review on Ketogenic Diets in Athletes Whey Protein vs. Beef Protein Show Notes: 00:00 – Welcome back to the Hart2Heart Podcast with Dr. Mike Hart 02:30 – Collagen and skin health 08:30 – Ketogenic diets for athletes 14:00 – Protein intake for athletes 18:00 – Intermittent fasting vs caloric restriction 25:00 – Seed oils: myths and facts 30:00 – Semen retention: debunking the myths 35:00 – Soy and hormones 38:30 – Soy consumption and hormonal effects 39:30 – Whey protein: benefits and misconceptions 42:30 – Post-workout nutrition myths 45:00 – Insulin sensitivity and carbohydrate timing 54:00 – Protein intake strategies 57:00 – Calories and diet composition 57:14 – “A calorie is a calorie, but depending on your diet's composition, you'll absorb and utilize very different amounts of calories from food.” 01:01:00 – Debating dietary approaches 01:05:00 – Cardiovascular health markers 01:12:00 – Conclusion and contact information   — The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to  cutting through the noise and uncovering the most effective strategies for optimizing health,  longevity, and peak performance. This podcast dives deep into evidence-based approaches to  hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise  protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.   Beyond health science, we tackle the intersection of public health and politics, exposing how  Policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.   Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).   If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect on social with Dr. Mike Hart: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart  

A nova diretriz da ESC/EAS 2025 em Dislipidemia chegou para mudar a forma como conduzimos nossos pacientes. O documento reforça o uso de escores na estratificação de risco, define metas de LDL ainda mais agressivas e traz para a linha de frente novas armas terapêuticas como o ácido bempedoico, o evinacumabe e o icosapent etílico.No episódio, Fernanda Justo e Raphael Rossi recebem Fernanda Del Castanhel para uma discussão prática e direta sobre:Como aplicar as novas metas de LDL em muito alto, alto, moderado e baixo risco.O papel dos fatores modificadores de risco que podem reclassificar o paciente.As novidades das terapias combinadas e o impacto dos estudos recentes como CLEAR Outcomes, IMPROVE-IT, PACMAN-AMI e HUYGENS.O que fazer em cenários especiais como HIV e pacientes oncológicos em uso de antraciclina.Minutagem:(01:50) - Como é feita a classificação e avaliação cardiovascular conforme a nova diretriz da ESC(14:15) - O que fazer com pacientes que tenham score de risco intermediário?(18:00) - O que fazer com o a "LPAzinha"?(21:30) - Quais são os novos alvos terapêuticos?(23:35) - Novidades na terapia terapia hipocolesterolemiante?(33:50) - Manejo hipolipemiante no paciente com SCA?(38:44) - Quais as atualizações no tratamento da hipertrigliceridemia?(43:40) - Novidades no tratamento do paciente com HIV(47:35) - Novidades no tratamento do paciente com neoplasia_____________________________Assine agora! Revisões didáticas de Cardiologia, semanalmente na DozeNews PRIME: a maneira mais leve e rápida de se manter atualizado(a), através do link dozeporoito.com/prime

September is Cholesterol Education Month. In this episode of Intelligent Medicine, Jim LaValle, a clinical pharmacist and certified clinical nutritionist, details cholesterol's importance and its implications for cardiovascular health. He delves into the nuances of cholesterol types, the historical shifts in perceptions of cholesterol, and how dietary and lifestyle factors influence cholesterol levels and cardiovascular risk. Jim provides expert insights into the roles of LDL and HDL cholesterol, the significance of cholesterol particle size, the impact of carbohydrates on cholesterol, and the benefits of aged garlic extract and other supplements. The conversation emphasizes the importance of comprehensive lipid testing, understanding individual risk factors, and integrating both lifestyle modifications and, when necessary, medications into cardiovascular preventive strategies. The episode concludes with a discussion on the role of health policies and the future of integrative health approaches.

Dr. Hoffman continues his conversation with Jim LaValle, a clinical pharmacist and certified clinical nutritionist, detailing cholesterol's importance and its implications for cardiovascular health. 

Join my FREE 3-Day Water Fast Challenge - October 15th. It's the exact protocol I use with pro athletes and Fortune 500 CEOs to flush inflammation and kickstart autophagy. Sign up here! http://bit.ly/4nTILPt Your immune system is either your greatest biological asset or your weakest link, and my conversation with Barbara O'Neill just revealed the secrets to strengthening it, by simply going back to the basics. The beauty of Barbara's approach is its simplicity and accessibility. These aren't expensive biohacks, but rather, foundational biological principles that honor how your immune system actually functions. Join the Ultimate Human VIP community for Gary Brecka's proven wellness protocols!: https://bit.ly/4ai0Xwg Get Barbara O'Neill's books here: http://bit.ly/3IcxjPH Connect with Barbara O'Neill Website: http://bit.ly/3Io9PXS YouTube: http://bit.ly/48ti53j Instagram: http://bit.ly/3Kf1LZV TikTok: http://bit.ly/4nHXZ9N Facebook: http://bit.ly/4mp8bTT Thank you to our partners H2TABS: “ULTIMATE10” FOR 10% OFF: https://bit.ly/4hMNdgg BODYHEALTH: “ULTIMATE20” FOR 20% OFF: http://bit.ly/4e5IjsV BAJA GOLD: "ULTIMATE10" FOR 10% OFF: https://bit.ly/3WSBqUa EIGHT SLEEP: SAVE $350 ON THE POD 4 ULTRA WITH CODE “GARY”: https://bit.ly/3WkLd6E COLD LIFE: THE ULTIMATE HUMAN PLUNGE: https://bit.ly/4eULUKp WHOOP: JOIN AND GET 1 FREE MONTH!: https://bit.ly/3VQ0nzW MASA CHIPS: 20% OFF FIRST ORDER: https://bit.ly/40LVY4y VANDY: “ULTIMATE20” FOR 20% OFF: https://bit.ly/49Qr7WE AION: “ULTIMATE10” FOR 10% OFF: https://bit.ly/4h6KHAD A-GAME: “ULTIMATE15” FOR 15% OFF: http://bit.ly/4kek1ij PEPTUAL: “TUH10” FOR 10% OFF: https://bit.ly/4mKxgcn CARAWAY: “ULTIMATE” FOR 10% OFF: https://bit.ly/3Q1VmkC HEALF: 10% OFF YOUR ORDER: https://bit.ly/41HJg6S BIOPTIMIZERS: “ULTIMATE” FOR 15% OFF: https://bit.ly/4inFfd7 RHO NUTRITION: “ULTIMATE15” FOR 15% OFF: https://bit.ly/44fFza0 GOPUFF: GET YOUR FAVORITE SNACK!: https://bit.ly/4obIFDC GENETIC TEST: ⁠https://bit.ly/3Yg1Uk9 Watch  the “Ultimate Human Podcast” every Tuesday & Thursday at 9AM EST: YouTube: https://bit.ly/3RPQYX8 Podcasts: https://bit.ly/3RQftU0 Connect with Gary Brecka Instagram: https://bit.ly/3RPpnFs TikTok: https://bit.ly/4coJ8fo X: https://bit.ly/3Opc8tf Facebook: https://bit.ly/464VA1H LinkedIn: https://bit.ly/4hH7Ri2 Website: https://bit.ly/4eLDbdU Merch: https://bit.ly/4aBpOM1 Newsletter: https://bit.ly/47ejrws Ask Gary: https://bit.ly/3PEAJuG Timestamps 00:00 Intro of Show 02:06 Going Back to the Basics 06:58 Good Sources of Nutrition for Infants 08:50 Possible Causes of Autism 11:35 Impact of Sanitation & Vaccination in Children's Health 16:10 Good Absorption vs. Malabsorption 19:15 Immune System is the Ability of the Body to Heal Itself 21:45 The Theory of Immunofatigue  24:21 How to Strengthen the Immune System 33:03 Recommended Nutrition for a Stronger Immune System 39:00 Strengthening the Immune System Starts with the Gut 44:46 Vaccinations = Childhood Poisoning Program 53:37 Healing Powers of Nature and Normalcy 57:27 Sleep is the Human Superpower 59:35 The Rise of Infertility 01:02:33 Impact of the Oral Microbiome 01:08:50 Debunking the Myths on LDL & Cholesterol 01:15:31 Taking Good Care of the Brain 01:23:21 What does it mean to you to be an “Ultimate Human?” The Ultimate Human with Gary Brecka Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user's own risk. The Content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. Learn more about your ad choices. Visit megaphone.fm/adchoices

Current treatments for heart disease fail to address root causes. Stents and bypass surgery only restore blood flow temporarily without tackling underlying endothelial dysfunction and inflammation driving heart disease Despite their ability to lower cholesterol, statins have limitations. While these drugs lower LDL cholesterol by 25% to 35%, they don't address oxidative damage or rebuild vessel health, leaving underlying inflammatory processes unchanged Excess linoleic acid (LA) from vegetable oils fuels heart disease. Modern diets contain 7.2% LA, as opposed to 2.8% a century ago. This creates mitochondrial dysfunction and dangerous oxidized LDL cholesterol formation Reducing LA intake shows measurable cardiovascular benefits. Limiting LA to under 5 grams daily reduces inflammatory markers like hsCRP by 15% and IL-6 by 10% within weeks Novel approaches like nanoparticle chelation show promise. Targeted delivery systems can address calcified plaques directly, offering more precise treatment than traditional intravenous methods at lower costs

If you or someone you love has had a heart attack, stent, bypass, or high calcium score, this episode is for you. In this episode, Dr. Robert Todd Hurst, MD, FACC, FASE breaks down the 10 most critical facts about coronary artery disease (CAD), from understanding the real risks, to reversing progression through precision treatment, to the surprising link between muscle mass, insulin resistance, and heart health. You'll learn what your doctor may not have told you, and how to protect your heart with the best available science and strategy.  Key Time Stamps:  00:45 – What coronary artery disease means & common fears after stents or bypass  01:37 – The #1 thing to know & the staggering stats behind heart disease in the U.S.  02:17 – Who is in the highest risk category   02:55 – Why >90% of heart disease is preventable (and how)  03:15 – Understanding insulin resistance and its role in artery disease  04:22 – What your LDL and ApoB numbers should really be  05:25 – Why “mildly elevated” blood pressure isn't actually mild  05:55 – The powerful link between fitness, muscle mass, and longevity  06:42– Why visceral fat matters more than BMI or total body fat  07:04 – How mental health, stress, and sleep impact your heart  07:20 – The danger of waiting: 25% of heart disease presents as sudden death  08:05 – Why can HealthspanMD prevent heart disease when the numbers are so bleak  09:33 – What the Heart Longevity Program at HealthspanMD includes  10:55 – The team, tools, and assessments that make this different  13:10 – The timeline for Heart Longevity Program at HealtspanMD  14:25 – Why now? What happens when people wait too long  This information is for educational purposes only and is not medical advice. Don't make any decisions about your medical treatment without first talking to your doctor.    Connect with HealthspanMD:  https://www.linkedin.com/company/healthspanmd/   https://www.facebook.com/healthspanmd   https://www.instagram.com/healthspanmd/  https://quiz.healthspanmd.com/    

When someone's LDL cholesterol hits 574 mg/dL, doctors typically expect the worst. But what if everything we think we know about cholesterol and heart disease risk is incomplete?In this episode, I sit down with researchers Nick Norwitz, Adrian Soto-Mota, and Dave Feldman to discuss their groundbreaking study on lean mass hyperresponders - a rare population who develop extremely high LDL cholesterol on ketogenic diets despite being lean, fit, and metabolically healthy. Their recent paper "Plaque Begets Plaque, ApoB Does Not" challenges conventional wisdom by showing that in this unique population, neither LDL cholesterol nor ApoB levels predicted plaque progression over one year of follow-up. Instead, existing plaque was the strongest predictor of future plaque growth. We explore the proposed lipid energy model that may explain why some people's cholesterol skyrockets on keto, discuss the limitations and implications of their findings, and examine what this means for personalized cardiovascular risk assessment. This conversation touches on fundamental questions about causality in medicine, the importance of studying outlier populations, and why a one-size-fits-all approach to cholesterol management may be missing crucial nuances.

Please Subscribe and Review: Apple Podcasts | RSS Submit your questions for the podcast here   Show Notes: Train with Morpheus Radiance of the Ordinary by Tara Couture Precision Health Reports- Dr. William Cromwell Power Athlete Radio Huberman Lab: Pavel Tsatsouline: The Correct Way to Build Strength, Endurance & Flexibility at Any Age Cronometer Questions:    Fueling jiu jitsu Cole writes:  Robb! Hoping I can get your input here… I am a blue belt in jiu jitsu, been doing it for exactly 3 years now. I am on a 95% paleo diet. I will swerve off the road for some pho or random foods when we are out but nothing terrible. 100% no sugar, no processed foods or bread. When I am consistent in jj I can roll one after another and not get too exhausted. I have been good on my diet this year, I have been going to jj 3-4 times a week BUT I have also added in kettlebell circuit training 5x a week for the past 2 months. I am trying to up my strength, at 38 these young fuckers are tearing me up! Anyways, I am exhausted quickly when I roll now and it's frustrating. Can I simply change my diet? I eat a lot of meat, mainly beef. Pretty much stick to meat, veggies and fruit. I don't want to let up on either but shit maybe I need to. Maybe I am not fueling myself enough? Should I eat MORE? Hoping this finds you! Would really appreciate your input.   Looking for podcasts about lifting for health Kristi writes:  Hi Robb and Nicki,  I've been craving some content about lifting lately, and the best YouTubers I know of don't seem to have audio-only podcasts, or they are heavily science and bodybuilding based. The science and bodybuilding is great, but I also like learning about stuff that will help me be fit and strong and mobile, not just pure bodybuilding. I was listening to Robb's old Paleo Solution episodes with Greg Everett and they are great, it's a good mix of good information but also always the caveat that it really depends what you want to do. Greg and Robb would answer the question based on what an Olympic lifter or a powerlifter might do, but also what you might want to do for general health and life. Thanks for any thoughts you might have about this, and thank you for the great work you've done over all these years! PS I listen to a lot of podcasts, so I won't listen to yours any less if you share some good podcast ideas!   Post Heart Attack plan Frederick writes:  Hello Nicki and Robb! I am one of your original dedicated five listeners who now wish he would have listened more carefully to your incomprehensive ramblings! I have written you a question before regarding relevant testing to assess cardiovascular health, what I am now about tell you makes that question irrelevant. I also wrote you a separate e-mail about this, but to my question. It regards an issue with my extremely elevated LDL (696) which has been a concern for me. On August 19 I got the answer to my concerns through a heart attack and a 10 minute cardiac arrest. Thankfully I survived and am able to write this. My story is that I have been keto since 2012 and 95% carnivore since early 2020 (meat, a lot of eggs, full fat dairy and occasionally fish. A few plants like onions and mushrooms for taste). I am 45 years, 10% bodyfat and very athletic since adolescence, so no pre-existing conditions and no cheat days, cheat days is just not who I am. So healthy, athletic and on the "perfect diet" for 15 years and still got heart disease.     Sponsor: The Healthy Rebellion Radio is sponsored by our electrolyte company, LMNT. It turns out that electrolytes don't need to be brightly colored and full of sugar...in fact, the brightly colored and highly sugared concoctions on store shelves often contain very few electrolytes…the sodium, magnesium, and potassium that your body needs to perform at its best. That's why we created LMNT! Become an LMNT INSIDER and buy 3 boxes and get the 4th box free! As always, LMNT offers no-questions-asked refunds on all orders - so you can try  LMNT 100% risk free.  Click here to get your LMNT electrolytes   .

FMF YouTube: https://www.youtube.com/@funmedFMI Center for Optimal HealthWebsite: fmioptimal.comInstagram: @fmioptimalFunctional Medicine of Idaho:Website: funmedidaho.comInstagram: @funmedidahoWe provide the highest quality supplements with responsible sourcing and the utmost commitment to purity funmedshop.com + more resources on IG: @funmedfoundations

Statin Myopathy   Guest: Stephen Kopecky, M.D. Host: Sharonne Hayes, M.D.   Statins are very helpful to lower LDL cholesterol and subsequently lower cardiovascular risk.  Studies of statins have excluded subjects that are statin intolerant which is usually due to muscle symptoms such as aches, called myalgias, muscle cramps, or weakness.  One of the most significant predictors of statin intolerance is the dose -the higher the dose, the more likely to develop intolerance.  Accepted in recommended ways to minimize intolerance is to use generic combination therapy with a lower dose statin and a cholesterol absorption inhibiting agent such as ezetimibe.  Newer agents such as PCS K 9 inhibitors and inclisiran, both given subQ, and bempedoic acid may reduce statin muscle symptoms.   Topics Discussed: Is any statin more or less likely to cause statin associated muscle symptoms? Are there any protective medications that can minimize statin myalgias? What newer non-statin agents have been shown to reduce risk of myalgias? How is treating high cholesterol levels becoming more like treating blood pressure?     Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode.   Podcast episode transcript found here.

In episode 56 of Going anti-Viral, Dr Steven Grinspoon joins host Dr Michael Saag to discuss managing cardiovascular health in people with HIV. Dr Grinspoon is a clinician in the Neuroendocrine and Pituitary Tumor Clinical Center and faculty member at the Massachusetts General Hospital, and a Professor of Medicine at Harvard Medical School. He is a clinical researcher who studies hypothalamic control of body weight and fat distribution in obesity and lipodystrophy with a focus on the metabolic and cardiovascular consequences of visceral fat accumulation. Dr Grinspoon provides an overview of cardiovascular disease in people with HIV including a review of the REPRIEVE study that evaluated if statin medication is effective to prevent heart disease among people with HIV. Dr Saag and Dr Grinspoon detail the REPRIEVE study results demonstrating that statins lower baseline low-density lipoprotein (LDL) cholesterol levels and discuss the cardiovascular health benefits of lowering LDL cholesterol levels. They discuss arterial plaque, how it is measured and whether plaque can regress individuals on statins. Finally, Dr Saag and Dr Grinspoon discuss goals for follow-up studies to REPRIEVE and other studies looking into the benefits of statins in other populations.0:00 – Introduction1:28 – Overview of cardiovascular disease in people with HIV 3:23 – Overview of the REPRIEVE study, which evaluated if statin medication is effective to prevent heart disease among people with HIV10:51 – REPRIEVE study results lowering baseline LDL cholesterol                       13:26 – Follow-up studies in people who do not have HIV16:20 – How plaque is measured in the arteries19:40 – Regression of plaque in patients using statins 21:15 – Top goals for follow-up studies to REPRIEVEResources: REPRIEVE Study: https://www.reprievetrial.org/ __________________________________________________Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral's host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode.Follow Going anti-Viral on: Apple Podcasts YouTubeXFacebookInstagram...

Send us a textDr. Josh Wageman is a Clinical Lipid Specialist with multiple doctoral degrees who formerly practiced in Endocrinology. His PhD work focused on cholesterol disturbances in Alzheimer's Disease, and although he also has a Doctorate in Physical Therapy, he is best known for his role in teaching lipid physiology.He serves as an adjunct professor at several medical programs and his goal is to help you, whoever you are, NOT have heart attacks, strokes, and dementia by explaining complicated biochemical concepts in a relatable way!Employing a smorgasbord of metaphors, pictures, and catchphrases, his latest book The Home Security System and the Lipid Neighborhood serves as a valuable reference for clinicians and non-clinicians alike, bringing refreshing relatability to complex biochemical topics. Through a lipid-lens, you'll learn, laugh, and love your way through its pages…and in the end, you'll undoubtedly add “life to your years!”Dr. Josh Wageman is active in Youth Ministries at Heritage Bible Church in Boise, Idaho, and resides there with his family. He also enjoys Crossfit, basketball, Ultimate Frisbee, and all sports that don't involve skates.Find Dr. Wageman at-Amazon- The Home Security System and the Lipid Neighborhood IG- @wagemanjoshLK- @Josh WagemanFind Boundless Body at- myboundlessbody.com Book a session with us here!

 Today on Beating Cancer Daily, Saranne welcomes back functional medicine expert Jacqui Bryan for an in-depth look at berberine—a natural compound generating major buzz as “Nature's Ozempic” on platforms like TikTok. With excitement high from both Saranne and Jacqui, the conversation explores berberine's traditional use in Chinese and Ayurvedic medicine, its modern reputation for supporting blood sugar control, heart health, weight management, cognitive function, and even potential anti-cancer qualities. Saranne highlights the supplement's growing popularity among those seeking natural alternatives to pharmaceuticals and underscores the importance of professional guidance before starting any supplement, especially for those navigating cancer, like survivors who are wary of synthetic drugs or those living with conditions such as Stage IV cancer.Jacqui Bryan is a certified nutrition specialist, whole health educator, certified health coach, and registered nurse. Her multidisciplinary, functional medicine background empowers others to take charge of their health through evidence-based, holistic approaches. Jacqui is passionate about translating the latest research into practical wellness strategies and is known for her ability to make complex topics both accessible and actionable for those managing chronic illness or seeking better overall health.“I love it when we can find things in nature that can improve our health, which I think is a lot of what we've been doing with this podcast.” ~Jacqui BryanToday on Beating Cancer Daily:·     Berberine is a natural plant compound with a long history in traditional medicine, now being explored for its impacts on metabolism, blood sugar, and even cancer. ·     The supplement is often compared to pharmaceuticals like Ozempic and metformin, generating popularity as a “natural” alternative, especially for those hesitant to use synthetic drugs. ·     Berberine's most studied effects include blood sugar regulation, enhancing insulin sensitivity, and supporting energy production at a cellular level. ·     Its role in gut health is significant, potentially supporting microbiome diversity, improving digestion, and providing relief for conditions such as SIBO. ·     Potential heart health benefits include lowering LDL (bad) cholesterol and triglycerides, and possibly increasing HDL cholesterol, though results may be stronger for women. ·     Proper use—including dosing, timing (typically before meals), and supplement quality, should always be discussed with a healthcare provider, given potential drug interactions and contraindications. ·     Berberine is not suitable for everyone, especially those who are pregnant, breastfeeding, on statins, or already using GLP-1 medications. ·     Reevaluating supplement routines regularly and coordinating with medical teams is critical to ensure safety, efficacy, and the avoidance of unnecessary or harmful combinations. 2025 People's Choice Podcast Awards Finalist Ranked the Top 5 Best Cancer Podcasts by CancerCare News in 2024 & 2025, and #1 Rated Cancer Survivor Podcast by FeedSpot in 2024 Beating Cancer Daily is listened to in over 130 countries across 7 continents and features over 390 original daily episodes hosted by Stage IV survivor  Saranne Rothberg.   To learn more about Host Saranne Rothberg and The ComedyCures Foundation:https://www.comedycures.org/ To write to Saranne or a guest:https://www.comedycures.org/contact-8 To record a message to Saranne or a guest:https://www.speakpipe.com/BCD_Comments_Suggestions To sign up for the free Health Builder Series live on Zoom with Saranne and Jacqui, go to The ComedyCures Foundation's homepage:https://www.comedycures.org/ Please support the creation of more original episodes of Beating Cancer Daily and other free ComedyCures Foundation programs with a tax-deductible contribution:http://bit.ly/ComedyCuresDonate THANK YOU! Please tell a friend whom we may help, and please support us with a beautiful review. Have a blessed day! Saranne 

Potato intake and diabetes risk.How much daily leucine is required to regain muscle?

I have high LDL cholesterol and a '0' calcium score.  Why does my doctor insist I take a statin?How much vitamin D should I take?  Which product do you recommend?Some doctors assert omega-3s are proinflammatory.  What say you?Study: Magnesium intake may be beneficial in preventing pancreatic cancerDo you have any products to regrow hair?I have a calcium score, but prefer to avoid Lipitor.

You're listening to Burnt Toast! Today, my guest is Mara Gordon, MD.Dr. Mara is a family physician on the faculty of Cooper Medical School of Rowan University, as well as a writer, journalist and contributor to NPR. She also writes the newsletter Your Doctor Friend by Mara Gordon about her efforts to make medicine more fat friendly.Dr. Mara is back today with Part 2 of our conversation about weight, health, perimenopause and menopause! As we discussed last time, finding menopause advice that doesn't come with a side of diet culture is really difficult. Dr Mara is here to help, and she will not sell you a supplement sign or make you wear a weighted vest.This episode is free but if you value this conversation, please consider supporting our work with a paid subscription. Burnt Toast is 100% reader- and listener-supported. We literally can't do this without you.PS. You can always listen to this pod right here in your email, where you'll also receive full transcripts (edited and condensed for clarity). But please also follow us in Apple Podcasts, Spotify, Stitcher, and/or Pocket Casts! And if you enjoy today's conversation, please tap the heart on this post — likes are one of the biggest drivers of traffic from Substack's Notes, so that's a super easy, free way to support the show!And don't miss these:Episode 209 TranscriptVirginiaSo today we're going to move away from the weight stuff a little bit, into some of the other the wide constellation of things that can happen in menopause and perimenopause. Before we get into some nitty gritty stuff, I want to do Laurie's question about hormone replacement therapy, since that is still one of those topics that people are like, Is it good? Is it bad? I don't know.So Laurie asked: Is there a reason why a doctor would not want to prescribe hormone replacement therapy? My doctor seems more willing to treat individual symptoms instead of using HRT. Is that maybe because I'm still getting my period?MaraI love this question. Now my professor hat can nerd out about interpretation of scientific research! So first, I'll just briefly say, Laurie, no big deal that you said HRT. But just so everyone's aware, the preferred term is menopausal hormone therapy, MHT, or just hormone therapy, and it's not a huge deal. But I think the North American Menopause Society now uses “menopausal hormone therapy.” The thinking is, hormones don't necessarily need to be replaced. It comes back to that idea of, menopause is a natural part of life, and so the idea that they would need to be replaced is not totally accurate. VirginiaWe're not trying to get you out of menopause, right? The goal isn't to push you back into some pre-menopausal hormonal state. MaraBut again, not a big deal. You'll see HRT still used, and a lot of doctors still use that term. So I graduated from medical school in 2015 and I remember one of the first times that a patient asked me about using menopausal hormone therapy, I was terrified. And I was still in training, so luckily, I had a mentor who guided me through it. But I had absorbed this very clear message from medical school, which is that menopausal hormone therapy will cause heart disease, cause pulmonary emboli, which are blood clots in the lungs, and cause breast cancer.And I was like, “Ahhh! I'm gonna cause harm to my patients. This is scary.” I had also learned that hot flashes–they weren't life threatening. So a patient could just use a fan and she'd be fine, right? She didn't need medicine for it.VirginiaCool.MaraI think the dismissal of symptoms here is just straight up misogyny. That message of, oh, you should just live with this You're tough, you're a woman, you can do it. This is just the next stage of it. Is just misogyny, right?But the fear of using menopausal hormone therapy has a specific historical context. There was a major study called the Women's Health Initiative, and it was a randomized control trial, which is the gold standard in medical research. People were given estrogen and progestin to treat menopausal symptoms or they were given a placebo, and they didn't know which pill they took. But WHI was actually halted early because they found an increased risk of breast cancer. This was on the front page of The New York Times. It was a really, really big deal. That was 2002 or 2003. So even 15 years later, when I was starting out as a doctor, I was still absorbing its message. And I think a lot of doctors who are still in practice have just deeply absorbed this message.But there's a lot to consider here. The first issue is in the way that information about the Women's Health Initiative was communicated. Nerd out with me for a second here: There is a big difference between absolute risk and relative risk. And this is a really subtle issue that's often communicated poorly in the media.So I looked it up in the initial paper that came out of the Women's Health Initiative. There was a relative risk of 26 percent of invasive breast cancer, right? So that meant that the people who got the estrogen and progestin, as opposed to a placebo, had a relative increased risk of 26 percent compared to the placebo arm.VirginiaWhich sounds scary,MaraSounds terrifying, right? But the absolute risk is the risk in comparison to one another. And they found that if you're a patient taking the estrogen/progestin, your absolute risk was 8 people out of 10,000 women a year would get invasive breast cancer. So it's very, very small.And this is an issue I see in medical journalism all the time. We talk about relative risk, like your risk compared to another group, but the absolute risk remains extremely low.And just to round it out: I looked all this up about cardiovascular events too. Things like a heart attack, a stroke. So the absolute risk was 19. So there were 19 cases of a cardiovascular event out of 10,000 women in a year. People just freaked out about this because of the way that it was covered in the media. VirginiaI was fresh out of college, doing women's health journalism at the time. So I fully own having been part of that problem. We definitely reported on the relative risk, not the absolute risk. And I don't understand why. I look back and I'm like, what were we all doing? We ended up taking this medication away from millions of women who could really benefit from it.MaraI found a paper that showed between 2002 and 2009 prescriptions for menopausal hormone therapy declined by more than 60 percent. VirginiaI'm not surprised. MaraAnd then even up until the time I started my training, right in 2015, we're just seeing a huge decline in hormone therapy prescriptions.One other thing that's also super important to acknowledge about the Women's Health Initiative is that they enrolled women over 60, which is not really representative of women who want or need hormone therapy. So the average age of menopause is 51 and the vast majority of women who are experiencing symptoms that would respond well to hormone therapy are much younger. We're talking here mostly about hot flashes. Which we call vasomotor symptoms of menopause, but it's basically hot flashes. Women dealing with this are much younger, right? So they're approaching menopause, late 40s, and right after the menopausal transition, early 50s, and then they don't necessarily need it anymore, after their symptoms have improved.VirginiaAnd it will also be true that with women in their 60s, you're going to see more incidence of cancer and heart disease in that age group than in women in their 40s anyway, right? MaraRightVirginiaSo even the 19 cases, the eight cases—they were looking at a higher risk population in general. MaraYeah. And so there have been all these subsequent analyses, which is why now we're seeing menopausal hormone therapy sort of on the upswing. There's a lot of increased interest in it. The American College of Obstetricians and Gynecologists recommends it, the North American Menopause Society, the British Menopause Society; here's a full run-down. It's not that everybody needs it, and we'll get to that in a second, but it is a totally safe and appropriate treatment for—specifically and most importantly—for vasomotor symptoms of menopause. Like hot flashes. There's been all these further analyses of the Women's Health Initiative data and and then from other studies, too. And basically, it shows that when the hormone therapy is initiated before age 60, or within 10 years of menopause, there's a reduced risk of heart disease and reduced mortality.VirginiaWow! MaraSo the timing matters. Isn't that so interesting? The timing matters.Also, the route of administration matters. So what that means in English is that an estrogen patch seems to have a lower risk of blood clots. So one of those fears of the, you know, initial Women's Health Initiative data was that you might have an increased risk of blood clots. But it's something about the way that the estrogen is metabolized. It's not metabolized through the liver when it's absorbed through the skin, and something about that process seems to decrease the risk of blood clots.So that's why your doctor, if you're interested in menopausal hormone therapy, might recommend an estrogen patch rather than a pill.VirginiaGot it. MaraThere's a lot of ambiguity in all of this data, because, you know, we're talking about just huge numbers of people, and it's hard to sort of isolate variables when you're studying just like massive cohorts of people and trying to understand what you know, what factors affect your risk for which diseases. It's not clear that taking hormones prevents heart disease. And that's one of the big claims I see with menopause influencers, that every single person needs this.The data don't support it at this point in time, and the major menopause organizations do not recommend it as a universal preventative treatment for everybody. But it seems like there might be some sort of association that may become clearer as research continues. That said, now it seems like the pendulum is swinging in the opposite direction. I learned, “be afraid of menopausal hormone treatment.” And now all these menopause influencers are saying everyone should be on hormone therapy.I don't know the answer. And so the way that I try to parse through all of this noise is, you know, go to trusted sources, right? So I stick to society guidelines, like the North American menopause society, the British menopause society, they're run by world experts in menopause.VirginiaOkay, so we don't need to be terrified of hormone therapy, and you can be on it if you're still getting your period right? Just to finish Laurie's question.MaraIf you're still getting a period regularly, you're more in perimenopause than past the menopausal transition. And we will often use contraception to help and that you can have a lot of the same benefits from using contraception in that stage. It's also useful just because unintended pregnancy still can be totally a thing in your 40s. But yes, you can absolutely use traditional regimens of menopausal hormone therapy while you're still getting a period too. Just know it won't prevent pregnancy. VirginiaSince we talked a little bit about hot flashes, I'm gonna jump to Judy's question so we can kind of round that piece out: One of the things I am really struggling with is the way I have lost all ability to regulate temperature. I am boiling hot almost all the time, and the slightest thing makes me break out into a full sweat, which makes me not want to move at all.My doctor has not been super helpful in navigating this. What can I do to mitigate this issue? If anything, it is so very hard for me not to blame the size of my body for this, since the correlation seems so clear, smaller body less sweating, larger body sweating all the dang time.MaraJudy, I empathize first of all. Just one caveat I can't really give medical advice to Judy. There are a lot of things that could be going on, and it's really important that you see a doctor and get a full history and physical exam. But I will say that this is one of the things that menopausal hormone therapy is extremely helpful for, is hot flashes.VirginiaThat was my first thought! MaraThere are a lot of influencers who really overstate the benefits of hormone therapy, right? Hormone therapy is not really going to cause significant weight loss or prevent weight gain. It's not totally clear that it helps with mood symptoms or even sleep is a little more ambiguous. But the one thing it really works for is hot flashes. So that would be my thought: Start there. VirginiaAnd on the feeling like you want to blame your body for it: I don't know if Judy identifies as fat, but as someone who identifies as fat, I often feel like I'm sweatier now than when I was thinner. I run warmer. All my skinny friends will be bundled up in coats, and I still won't be wearing one in October. I do notice that. And I think that this is a situation where that is, even if those two things correlate— you're larger and you're sweatier—is that worth putting yourself through the hell of weight loss? You may decide yes, it is, if hormone therapy doesn't work for you.But that's one of those times where I bring it back to “What would actually make my daily life miserable?” I can drink water, I can be in AC, I'm gonna find a link to this nighttime cooling bed thing that my friend Claire Zulkey really loves. MaraI've heard of those!VirginiaI think there are options to mitigate your suffering with this. Medicine is definitely an option. Before you go to “okay, my body size has to be the thing that changes.”MaraI totally agree. I just deal with this all the time where people tell me in my clinic that they want to lose weight. And when I sort of gently ask, what are you hoping to achieve? What are your goals? They're often things that can be achieved through other means. Like, people say my clothes don't fit, right? And most of my patients are low-income, right? I'm not trying to be flippant about the idea that everyone can just go and purchase a new, you know, multi $1,000 wardrobe at the drop of a hat. But it is possible to get new clothes in affordable ways. Don't torture yourself with clothes that don't fit because you feel like weight gain is a moral failing. And I think that there are things that we can do to help keep us at a comfortable temperature, right wear clothes that feel, you know, that feel good. Air conditioning is an amazing modern invention. And, you know, cool beverages, ice cream. VirginiaPopsicle O'Clock is very important in my summer right now, very important. MaraWait, what's a popsicle clock?VirginiaOh, Popsicle O'Clock. It's just the time of day where you eat popsicles. It could be 9am it could be 4pm just whenever I feel like we need to add popsicles to a situation.MaraI think we all need more popsicles in our life, that is absolutely for sure.So I think what I'm hearing from Judy's question is once again, shame about body size, and also this myopic zooming in on weight loss as the only possible solution. Which I blame doctors for in many ways! Some people do benefit from weight loss, right? I'm not opposed to the idea that anybody would ever want to lose weight. I don't think that that's a betrayal of fat solidarity, necessarily. But that there are other things you can do just to make your life feel better in the meantime, or even if you choose to never pursue weight loss. There are things you can do to feel better, and we shouldn't deprive ourselves of those things.VirginiaAnd you don't know that it is the weight gain. It could be age and hormones, and those coincided with the weight gain for you personally. But there are lots of thin women getting hot flashes all the time too.Okay, this next question is from Michaela: I am super curious about the connection between perimenopause, menopause and mental health symptoms, specifically, an uptick in anxiety and depression. Is this a thing?We also got many questions about whether perimenopause and menopause exacerbate ADHD symptoms. MaraSo this is a question I get a lot from my patients, and I've seen a lot of discourse about online. And the short answer is: There is probably a connection between the hormonal changes of perimenopause and the menopausal transition and mental health. Do we understand it? No. So I mean, with ADHD specifically, I will say: This is really not my area of expertise. It's a very complex mental health condition, and our medical understanding of it is really rapidly evolving. I have many patients who have a diagnosis of ADHD but I'm typically not the one who diagnoses them. That being said: Estrogen affects neurotransmitters. Neurotransmitters are implicated in ADHD. Declining estrogen does seem to affect dopamine, in particular, which is implicated in ADHD. And anecdotally, I've had many of my patients say that they feel like their ability to focus and sustain attention decreases. And they experience brain fog as they enter perimenopause and menopause. So it's there's probably something going on, and a lot of researchers are really actively studying it, but we don't know yet.VirginiaDo we know if this is something that hormone therapy can help with?MaraSo I think the answer is, I don't know.VirginiaWhat about anxiety and depression?MaraI don't think the data are there, right? Hormone therapy is usually not considered a first line treatment for the mental health conditions that are often associated with the menopausal transition. But we have great medicines for those conditions. We have good treatments for ADHD, we have good treatments for anxiety and depression. And sometimes during the menopausal transition, patients might need an increase of those treatments. And that could mean going back into therapy, if you've been out of therapy, increasing your medications or restarting a med that you may have stopped years ago. Those are all totally valid approaches during this phase.And I guess what I'd say, is that it's okay to trust your body. And if you notice changes in your mental health associated with perimenopause or menopause itself, ask about it. Don't be afraid to advocate for yourself. And while hormone therapy doesn't look like it is an effective treatment specifically for those symptoms, there are other treatments, and you should feel empowered to ask about them.VirginiaThe next question goes back to some of the diet and exercise stuff we've touched on. This person writes: Since recently reaching menopause, my cholesterol has become high. I understand there is a proven link between menopause and increased cholesterol, and that weight is part of the picture. I'm trying to lower my cholesterol with focus on nutrition and exercise. But it is f*****g with my head because it feels like a very restrictive diet. I'd love any thoughts on the menopause cholesterol connection and keeping cholesterol low with nutrition and exercise without falling into the abyss of obsessing about how many almonds I've eaten.MaraOh, that is such a good question!VirginiaThe almond of it all. MaraAlmonds are really good in some scenarios, but also just like, kind of a sad snack. I always think about President Obama eating those, like, eight almonds, or whatever.VirginiaIt turns out that was a joke and he wasn't doing that. But just the fact that everybody assumed he would says a lot! MaraThat is hilarious, and I didn't know! And it just shows how with information online, the initial story sticks. Like to this day, 10 years later, I still thought that Barack Obama ate eight almonds as his indulgent midnight snack every single night. I hope the man is eating some ice cream and living his best life. Okay, so there is absolutely a link between menopause and elevated risk of cardiovascular disease. But even within the term cholesterol, there are different types. I wouldn't really say to a patient, “Your cholesterol is high.” One thing you might hear is “your LDL cholesterol is high,” which is known popularly as, the “bad” cholesterol. Which, again, moral language alert. But LDL cholesterol is a proxy for risk of cardiovascular disease. I will say it's not a great one; it's kind of a blunt instrument. We measure and we treat it, because we don't have other great ways of predicting cardiovascular risk. But it is not the full portrait, although it's certainly a risk factor for developing cardiovascular disease. And the transition of menopause seems to impact LDL, cholesterol, other biomarkers of cardiovascular disease, and increases your risk for cardiovascular disease.And what's interesting–I think we talked about this a little bit already, is that this happens, this this risk happens independent of normal aging.So, for example, women who go through menopause early start developing this increased risk earlier than women who go through menopause slightly later. And overall, we see that women develop cardiovascular disease, at rates lower than men, and at later in life than men. And there's a hypothesis that this has to do with menopause, right? That there's a protective effect of estrogen, but then when your estrogen starts to decline in menopause, it puts women at an increased risk compared to where they were pre-menopause.There's also some data to suggest that the severity of menopause symptoms—particularly vasomotor symptoms like hot flashes or sleep disturbances—may indicate risk for developing cardiovascular disease. So this is not to scare everyone, but it's good to have knowledge. If you're having really severe hot flashes, it may indicate that you are at slightly higher risk for developing cardiovascular disease than somebody who is not. The intention of having this knowledge is not to make you feel shame, and not to berate you for your belly fat or whatever. It's to have knowledge so that you can help mitigate risk factors in ways that feel aligned with your values and ways that feel aligned with the way that you want to pursue health in your life.And so I would approach this reader's or this listener's question with smy same approach to all of my patients questions. “I have hypertension, does that mean I need to lose weight?” “I have diabetes, does that mean I need to lose weight?” The answer is that we have many treatments that can help you address these concerns independent of weight loss. But this is not to say that you cannot pursue weight loss too, right? And if using a GLP-1 agonist to reduce your visceral adiposity is aligned with your values, and you can tolerate the side effects, and you feel good about it, and it's covered by your insurance….that's totally a reasonable approach. But it's not the only one. So I think what I'm hearing from this patient is the menopause flavor of what I do every single day in my work as a size inclusive doctor. Which is: How can we disentangle weight stigma and body shame from these questions of how to lead a healthy life? And the idea of giving you more information, I hope, is not to shame you or make you feel guilt for the relationship between body size and risk of cardiovascular disease, but instead, to give you information that might help you take proactive care of your body, right?And proactive care might mean committing to an exercise routine. Proactive care might mean taking a statin. A statin is a very common cholesterol medicine like Lipitor. It might mean getting your blood pressure under control and taking an antihypertensive.VirginiaI also want to say on cholesterol, specifically, I did a piece that I'll link to digging into the connection between nutrition and cholesterol. And the data is not as strong as I think a lot of doctors are telling folks.And I think the benefit of making dietary changes—the amount it could lower cholesterol—was not huge. It was like three points or six points or something in one of the studies we looked at. So if it's making you crazy to count almonds, it's possible that medication might be a more health promoting strategy for you. Because it will be less stressful and it will have a bigger benefit on your cholesterol than just trying to control it through diet and exercise.MaraYeah, I totally agree. I think there's a really strong genetic component that we haven't fully understood and medication is a totally reasonable approach and very safe approach. Honestly, statins are pretty benign medications. They're pretty inexpensive, pretty minimal side effects, which is not to say– nobody's paying me from the statin companies, I swear to God!–but yeah, like they're, they're pretty benign as medications go. And I think it's a totally reasonable way to approach this issue.VirginiaI just think it's one of those times where this is shame coming in, where it's like, “You should be able to fix this with how you eat and exercise, and so you don't get the medication unless you fail at that!” This is a framing that I've encountered from doctors. But what if we gave the medication, what if we also consider diet and exercise, but don't make that a pass/fail situation in order to earn the medication? MaraYeah, that's really interesting.And even the language you're using Virginia is what we use in the medical record, and I've tried to stop it. But the way we're taught to describe patients, is “patient failed XYZ treatment,” right? And I feel like we're both at once, overly invested in pharmaceutical treatments, right and underinvested. They're a very useful tool. And we moralize it, both pro and con? Sometimes, like, we moralize in favor of it. So if your BMI is 26 or above, you need to be on a GLP one agonist, which is just false, right?But on the other hand, I think we often underutilize medications because there's this sense that you're getting at —that you have to exhaust all of your like willpower options first, and it's somehow failing to use a med. And that is really false too. They're really useful tools. Science is really useful, and we shouldn't feel ashamed to use it.VirginiaAll right. And our last question, I like because it just will give us a chance to kind of sum up some key points: As a post menopausal woman, I feel like I'm swimming in information, and I'm overwhelmed by it all. What are Dr Gordon's top three pieces of advice out of all of the WHO meaning, if women at this time only did these three things, it would make the biggest difference, and then they just had it. You know, is, does it need to be different for perimenopause versus post menopause? Or maybe not.So what are your top three? Top three tips for surviving this life stage?MaraOh, my God, if only I knew! I'm flattered that you're asking, and I will do my best to answer, but I don't think there's a right answer at all.So I've thought about a couple things. I will say that, you know, longevity and wellness and health span is extremely complicated, but it's also kind of simple, right?So sometimes the advice that we've just heard over and over again is actually really, really good, right? So, sleep. Are we sleeping enough?Staying engaged with social relationships, that seems to be extremely important for longevity. And it's kind of amazing, actually. When they do these long-term studies on people who are thriving into old age, like they have really strong relationships. And that is so important.Moving our bodies and it does not need to be punishing. Workouts can be gardening. I know Virginia, I love receiving your gardening content online. Gardening is an amazing form of exercise, and can be very life affirming, and does not need to feel like punishment. Just getting up, moving our bodies, sleeping enough, maintaining relationships, cultivating a sense of purpose and meaning in our lives. It's actually been really studied right, that people who have a sense of meaning and have a sense of purpose in their lives tend to live longer and live longer, healthier lives.So all of this is to say that like it's complicated, but sometimes it's not. And there are a million people on the Internet who want to sell you a miracle drug, a miracle supplement, a miracle weighted vest, whatever. But sometimes simple, Simple is good. Easier said than done, right?VirginiaYeah, but start simple. That's wonderful.MaraCan I ask? Virginia, what would your advice be? VirginiaI love the three areas you hit on: Sleep, social relations and exercise or moving your body. None of those are about weight loss or dieting. I think that's really helpful for us to keep in mind that the things that might protect our health the most can also be very joyful as well. The idea that doing things that makes you happy and reduce your stress can be health-promoting is great. And I think that's something especially in midlife. We are all incredibly busy. We're holding a lot of things together. A lot of us are caregivers, maybe sandwich generation caregivers. So prioritizing your own joy in that feels really wonderful.ButterVirginiaAll right, so speaking of joy, let's do some Butter! Dr. Mara, what do you have forus?MaraI have a Philadelphia-specific one, but hopefully it can be extrapolated to our listeners in different locations. So I have recently been really craving soft serve ice cream. And so I googled best soft serve in Philadelphia, and I found this Vietnamese coffee shop called Càphê Roasters, which is in North Philly. In a neighborhood called Kensington. And it has condensed milk soft serve ice cream. So good.And so I recently, I had to give a lecture at a medical school in the north part of the city early in the morning. It was like, 8am and I was like, “Oh, I'm never up in this neighborhood. I gotta get over there.” And I went after I gave my lecture, and I bought myself ice cream at 10:30 in the morning. And I ate it in my car, and it was so good. Condensed milk. So good. But soft serve in general, is my Butter. But for those of you in Philly, go to Càphê Roasters in Kensington and get the condensed milk. It is chef's kiss, delicious.VirginiaAmazing. I'm gonna double your Butter and say ice cream in general is my Butter right now. We have a spare fridge freezer that I have just been loading up with all of the popsicles to get us through summer. But also: Ice cream dates. Something that comes up a lot for me as a co-parent is figuring out how to have one on one time with my kids. Since we have joint custody, they move as a package. So I get kid-free time, which is wonderful, but when they're with me, it's just me. So one thing I've been figuring out is pockets of time when I can take one kid out for ice cream. It's usually when a sibling is at another activity, and so we have an hour to kill, and often we would just like, wait for the activity, or go home and come back, and then you're just driving.And now I'm like, No, that will be our ice cream break!MaraI love that.VirginiaSo one kid's at the library doing her book trivia team stuff, and the other kid and I are getting ice cream while we wait for her. And it's great one on one time with kids. Obviously, the ice cream is delicious. The other thing I've realized, especially if you have younger kids who are still building restaurant skills, ice cream is a great practice run at being a person in a restaurant, which is really hard for kids understandably. It is one food thing that they're excited to go do. And you do have to sit and practice eating it somewhat neatly. There's a high mess potential. My pro-move for that is, always have wipes in your car, bring a pack of wipes in. MaraI love that, and it's so intentional about sort of creating traditions with kids. That feels really special. But I will say I had my ice cream solo, and that was also really good solo ice cream too.The Burnt Toast Podcast is produced and hosted by Virginia Sole-Smith (follow me on Instagram) and Corinne Fay, who runs @SellTradePlus, and Big Undies.The Burnt Toast logo is by Deanna Lowe.Our theme music is by Farideh.Tommy Harron is our audio engineer.Thanks for listening and for supporting anti-diet, body liberation journalism! This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit virginiasolesmith.substack.com/subscribe

Dr. Dominic D'Agostino (@DominicDAgosti2) is a tenured associate professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine and a Visiting Senior Research Scientist at the Institute for Human and Machine Cognition.This episode is brought to you by: Helix Sleep premium mattresses: https://HelixSleep.com/Tim (27% off all mattress orders)Momentous high-quality creatine: https://livemomentous.com/tim (code TIM for up to 35% off)AG1 all-in-one nutritional supplement: https://DrinkAG1.com/Tim (1-year supply of Vitamin D plus 5 free AG1 travel packs)Timestamps:[00:00:00] Start.[00:14:43] Why I'm interested in ketogenic strategies for neurodegenerative prevention.[00:16:18] Mary and Steve Newport's ketone-linked temporary cognitive improvements.[00:18:18] A mechanisms overview for Alzheimer's/dementia.[00:21:25] The immune system as longevity's "fifth horseman" — and why metabolic control is key.[00:22:04] How to measure ketones and GKI.[00:23:00] Fasting vs. ketogenic diet.[00:24:18] There's nothing fishy about sardine fasting.[00:28:32] My hiatal hernia discovery and increased cancer risk concerns.[00:30:04] HSCRP as a superior biomarker to LDL for cardiovascular risk.[00:31:57] Glucose tolerance testing revelations and CGM importance.[00:31:57] Upgrading the metabolic machinery through keto without getting bored.[00:42:07] What do do if you, like Dom and me, are among the 30% who suffer from cholesterol hyperabsorption.[00:43:42] Dom's day-to-day diet regimen.[00:45:56] How Dom optimizes his aging dogs with ketones, SARMs, and supplements.[00:51:30] Supplementing for sleep disruption while fasting.[00:55:41] Why Dom doesn't have misgivings about melatonin.[00:59:15] Shingles prevention through fasting protocols.[01:00:15] Immune system modulation: Innate vs. adaptive, vegan vs. ketogenic.[01:03:54] Dom at 50-something: Current meal timing and composition.[01:05:57] Blue zone observations: Greek and Sardinian longevity habits.[01:08:16] Ketogenic diet initiation tips: MCT, electrolytes, and fasted cardio.[01:15:18] Ketone metabolic therapy for cancer.[01:18:15] The metabolic psychiatry revolution.[01:22:10] The soothing effects of hyperbaric oxygen and ketosis on seizure sufferers.[01:28:27] Metformin vs. berberine.[01:31:43] The low-dose neuroprotective potential of GLP-1 drugs.[01:34:58] NAD research: MIB-626 and stabilized forms for mitochondrial health.[01:39:48] Idebenone, CoQ10, and the Deanna protocol for ALS.[01:42:05] Dom's supplement short list: CoQ10, creatine, ketones, vitamin D, melatonin.[01:44:43] KetoNutrition.org, Metabolic Health Summit, Audacious Nutrition, veteran-focused research protocols, and other parting thoughts.*Show notes for this episode: https://tim.blog/2025/09/03/dr-dominic-dagostino-all-things-ketones/For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Cold brew coffee may be smooth, trendy, and easy on the stomach — but is it secretly driving up your cholesterol? In today's episode, I'll break down the science behind cold brew, how it differs from hot coffee, and why, if you've had bariatric surgery or use GLP-1s, you should pay attention to this heart-health connection. Before you pour your next glass, listen in…Need resources to help with your bariatric lifestyle? Check out our Bariatric Tools page with meal plans, recipes, GLP-1 guide, etc.AD:Visit Procarenow.com now for all of your vitamin and mineral, calcium and protein needs. Use Code: BSS10 to save $Rate, Review & Follow on Apple Podcasts:"I love Dr. Susan and Bariatric Surgery Success." If this sounds like you, would you please rate and review my podcast? I love hearing from you, and it's actually super easy for you to leave a podcast rating. Wherever you listen to the Bariatric Surgery Success podcast, go to the review section and usually click a quick star rating. If you feel like taking it one small step further, please write a review if there's a place for one. Thank you!SummaryIn this episode, Dr. Susan Mitchell explores the health implications of cold brew coffee, particularly its effects on cholesterol levels. She discusses the differences between cold brew and traditional coffee and the importance of filtering coffee to manage cholesterol. The conversation emphasizes the need for awareness among bariatric surgery patients and those on GLP-1 medications regarding their coffee consumption and its potential health impacts.TakeawaysCold brew coffee may affect cholesterol levels differently than traditional coffee.Filtered coffee has minimal impact on cholesterol levels.Unfiltered coffee can increase LDL cholesterol due to diterpenes.Bariatric patients should consult their dietician before consuming caffeine post-surgery.Using a good filter can help reduce cholesterol-raising compounds in coffee.Cold brew is less acidic and may be easier on the stomach.Coffee contains bioactive compounds that can benefit heart health.Consider adding protein powder and cinnamon to cold brew for a nutritious drink.Chapters00:00Introduction to Cold Brew Coffee and Health Concerns02:46Understanding Cold Brew vs. Traditional Coffee05:05Cholesterol Levels and Coffee Brewing Methods07:55Healthy Coffee Alternatives and Recipes

Stephen Thomas interviews Dave Feldman about his recent study on near-lean mass hypersponders and the implications of high LDL cholesterol levels. They discuss the study's methodology, key findings, and address criticisms regarding the narrow participant range and the use of contrast dye in scans. The conversation also explores the relationship between LDL levels, health markers, and lifestyle factors that may contribute to plaque regression. Feldman emphasizes the importance of understanding the context of health markers and the need for further research in this area.Chapters00:00 Introduction to the Keto CTA Study06:55 Key Findings from the Study11:36 Critiques and Limitations of the Study16:01 The Role of Contrast Dye in Scans19:59 Understanding Regression in Plaque27:08 The LDL Dilemma and Metabolic Health37:51 Future Directions and Closing Thoughts

We hear a lot about LDL cholesterol as a contributor to heart disease, however there's an inherited cholesterol containing particle that also plays a factor. On this episode, we sit down with Dr. Hugh Coyne to learn more about Lipoprotein(a), or Lp(a), and how its presence affects our risk for cardiovascular disease.Dr. Hugh Coyne is a general practitioner and the co-founder of Coyne Medical in Parsons Green, London. Coyne Medical, has two state of the art Private Doctors Surgeries. They aim to lead the market in providing high quality accessible healthcare, using the latest technology and evidence to offer patients individualised holistic care.Episode Links:Learn more about Coyne MedicalFollow Dr. Hugh on social media: Instagram | LinkedInAbout Propel:Propel is the purpose-built well-being platform designed to help you develop a culture of well-being and bring your vision to life. Propel helps you launch a truly engaging program with flexible technology that tailors the experience to your diverse teams.Create a unique well-being experience from within. See how Propel can help by scheduling a free strategy session at propelwellbeing.com.

Dairy is often treated as a single food group, yet milk, yogurt, cheese, and butter can have very different effects on health. Some evidence links yogurt to favourable outcomes, while butter is known to raise LDL cholesterol. And then there's the paradox of cheese: high in saturated fat, but not consistently associated with higher heart disease risk. These complexities raise the question of whether the “dairy matrix” (the combination of nutrients and food structure) explains why not all dairy acts the same. In this episode, Prof. Jean-Philippe Drouin-Chartier, a nutrition researcher and registered dietitian, is on the show to examine what recent trials and large population studies tell us about dairy foods and cardiometabolic health. The discussion covers blood lipids, blood pressure, glucose metabolism, and how guidelines should interpret this evolving evidence. Timestamps [02:18] Interview start [09:38] Dairy consumption and type 2 diabetes [16:06] Dairy and cardiovascular disease [21:42] Dairy, blood pressure, and hypertension [25:56] Dietary guidelines and dairy [43:30] Key ideas segment (Premium-only) Related Resources Subscribe to Sigma Nutrition Premium Join the Sigma email newsletter for free Website: sigmanutrition.com Enroll in the next cohort of our Applied Nutrition Literacy course Referenced studies linked here  

Thank you for joining us for our 2nd Cabral HouseCall of the weekend! I'm looking forward to sharing with you some of our community's questions that have come in over the past few weeks…   Suzanne: Thank you for your time in advance. In late 2021, my husband was diagnosed with Stage IV prostate cancer. He underwent six rounds of chemo along with Eligard injections. After his last scans, whole body and bone, we were told the cancer is "stabilized". He is currently on 300 mg of Nubeqa 2x a day (down from 4 x because I asked about it) and Lupron injections every 3 months. We have consciously changed our diet (no added sugar, no alcohol, no processed foods) and he is doing pretty well, although, he does fatigue and sweat easily. My question is whether you believe that taking a couple of your home tests would be beneficial for him? I worry about these powerful drugs he is being given and have noticed a reluctance from the doctor about reducing his drugs any further. Thank you again!                                                Sheena: Hi Dr C! Hope you and your team are well. I recently went for blood work. I fasted for 14 hours and was wondering what your thoughts are specifically regarding my Lipid Panel and Iron Panel. My triglycerides is 1.83, Total 4.05, HDL 1.72 and LDL 1.63 (all mmol/L). For iron my levels are 37 umol/L, iron binding 0.70 umol/L, and ferritin 44 ugL. My Dr says she's concerned with my triglycerides. How can I lower it? And shes concerned with my ferritin and iron levels so shes sending me for a Hemochromatosis blood test to see why the levels are off. (My fasting glucose is 4.9, hbA1c is 5.2, TSH is 1.04 and Auto CBC is 3.8). Would love your thoughts and any food and supplementation recommendations would be appreciated! Love you and all the best to everyone on their health journey!                                                            Madhia: Hello My Dr is giving me a hard time to prescribe MRI for my breast exam. Do you have any Dr you can recommend that would help me in greater Los Angeles area?                                                                                                 Margie: My son, who is 46 years old has had Alpha-Gal for approximately 10 years. Now his wife has also been diagnosed with it. I am aware it is caused by a tick bite. He constantly has mass cell inflammation including breathing and allergy issues. Could you please explain specifically how this disease affects the body's immune system and which of your protocols should be used to bring the body back into balance. Will that particular protocol bring the body back into balance enough so that it will relieve the mass cell inflammation and they can return to eating mammal meat?                                                     Jackie: Hi Dr. Cabral thank you for all that you do. You have made a tremendous impact in my and my clients lives. My husband has just finally been diagnosed after 10 years of misdiagnosis with neurogenic TOS. We have a great rehab team working on the biomechanics and we are exploring Big 5 root causes. I was wondering what natural pain management methods you would recommend during the process pain is 10/10 and conventional medicines wants to basically kill the nerve or put him on Lyrica which neither are an option for us. We are exploring accupuncture, grounding and adrenal sooth/inflammasoothe/cbd protocol. Any other alternative inflammation reduction techniques or devices you would recommend? Could you do a podcast on natural pain management strategies for people with chronic pain?          Thank you for tuning into this weekend's Cabral HouseCalls and be sure to check back tomorrow for our Mindset & Motivation Monday show to get your week started off right! - - - Show Notes and Resources: StephenCabral.com/3495 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

We have the second episode in a series of conversations with Dr. Thomas Dayspring today.  The esteemed Dr. Dayspring is an expert on internal medicine and clinical lipidology. In this episode, we continue with our last conversation, diving into Lp(a) and the influences of gender, race, and menopause. We explain how estrogen is a PCSK9 inhibitor and explore the significance of brain health and risks for dementia. We tackle cholesterol synthesis and discuss the side effects of statins, clarifying who is most susceptible to their impact on the brain. We also examine the significance of the desmosterol biomarker, highlighting the level to aim for, especially when making decisions regarding cholesterol medications, and we answer one question from a listener.  You may want to listen to this insightful conversation with the renowned Dr. Dayspring more than once. He has graciously agreed to return and film additional episodes, where we will dive into more questions from listeners.  IN THIS EPISODE, YOU WILL LEARN: Why Lp(a) is like a wolf in sheep's clothing for many individuals How Lp(a) levels are higher in African Americans and women, especially after menopause  Dr. Dayspring highlights that Lp(a) particles are even more pro-inflammatory than LDL particles How PCSK9 inhibitors are the only drugs that significantly reduce Lp(a) Why do women have a higher risk of dementia than men? Dr. Dayspring explains ApoE as the key lipoprotein for brain cholesterol transport. How statins cross the blood-brain barrier to lower brain cholesterol Why desmosterol levels matter New therapies that can lower ApoB and Lp(a) Why imaging is essential for menopausal women with elevated ApoB and Lp(a) Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Connect with Dr. Thomas Dayspring On X (@Drlipid) On LinkedIn Journal Article: Atherosclerosis: Non-genetic influences on lipoprotein(a) concentrations  Journal of the American Heart Association: Trajectories of Blood Lipid Profiles in Midlife Women: Does Menopause Matter?

This week, Dr. Joel Kahn reviews the latest research on men's health, focusing on diet and prostate cancer. He highlights findings that support whole-food, plant-based diets and discusses the connection between prostate cancer, heart disease, and the cardiovascular risks associated with androgen deprivation therapy (ADT). Other topics covered include plant-based diets and disease rates, the role of LDL cholesterol in soft plaque formation, TMAO in abdominal aortic aneurysms and kidney disease, periodontal disease and its impact on heart health, saccharin and cardiovascular risk, extreme physical activity and carotid plaque, and the effects of Tylenol use during pregnancy.  Dr. Kahn also reviews new research on cyclodextrin suppositories, a paper examining the impact of statins on blood sugar, and the potential role of TUDCA as a possible antidote.  Resources mentioned in this episode include the cyclodextrin paper available at www.atherocare.com/drjoelkahn and details on TUDCA at https://shop.drjoelkahn.com/catalog/product/view/id/17560/s/tudca-tauroursodeoxycholic-acid-60-capsules/. Special thanks to our sponsor Igennus.com, use discount code DrKahn for all products.

Want a simple addition to your daily routine that can help lower cholesterol naturally?     On today's Cabral Concept, I'm sharing 5 science-backed drinks proven to lower your cholesterol.      I also share with you the exact amounts to consume shown in research to make a difference and how they can lower LDL cholesterol, improve blood pressure, reduce inflammation, and support overall heart health.     So join me on Cabral Concept 3485 to discover these 5 easy, research-supported drinks to help lower your cholesterol and how to work them into your routine for better cardiovascular wellness.     Enjoy the show, and let me know what you think!   - - - For Everything Mentioned In Today's Show: StephenCabral.com/3485 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!