Podcasts about ldl

Dr. Erin Faules speaks with Dr. Damon Forbes about Lp(a), a genetically influenced lipoprotein linked to cardiovascular disease risk. They discuss how Lp(a) differs from LDL, its role in plaque and clotting, and why a one-time test can help clarify long-term risk. The conversation covers who to screen and when, interpreting Lp(a) alongside apoB and metabolic health, evidence-based ways to lower overall cardiovascular risk, and emerging Lp(a)-lowering therapies

Send us a textCardiologist Dr. Michael Koren is joined by a 35-year-old patient "Tucker" to walk through his cardiovascular numbers and explain what it all means. The doctor explores a lipid profile and an advanced lipid profile from top to bottom, explaining everything from how LDL is calculated to what hs-CRP measures. Along the way, they discuss how diet, exercise, supplements, and medications can affect these numbers, how the numbers relate to your risk of a cardiovascular event (like a heart attack or stroke) and what, if any, interventions should be taken. This real-world-example shows how complex the world of cardiology and lipids is and gives helpful, actionable information based on the numbers you might see. This podcast is not medical advice, and all personal situations should be discussed with your physician.Be a part of advancing science by participating in clinical research.Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.comListen on SpotifyListen on Apple PodcastsWatch on YouTubeShare with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released.Follow us on Social Media:FacebookInstagramX (Formerly Twitter)LinkedInWant to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.comMusic: Storyblocks - Corporate InspiredThank you for listening!

“VO2 max is the best predictor of lifespan,” says Peter Attia, M.D. Peter Attia, M.D., physician, founder of Early Medical, and expert in the applied science of longevity, joins us today to break down the key levers for extending both lifespan and healthspan—from how to train for a higher VO2 max to the biomarkers that truly predict long-term health. - The most powerful habit for longevity (~6:15) - VO2 max (~8:55) - How to increase your VO2 max (~10:08) - Heart rate vs. perceived exertion (~12:35) - Attia's strength training routine (~15:20) - 2 exercises Attia stopped doing (17:00) - Diminishing returns in terms of exercise (~19:55) - His take on wearables (~21:25) - Cardiovascular disease markers (~23:38) - Lowering ApoB (~25:35) - Pharmaceutical interventions for LDL & ApoB (~27:50) - Neuroinflammation markers (~37:25) - Perspectives on statins (~40:45) - The role of nutrition (~42:50) - Potential benefits of GLP-1s (~45:00) - Peptides (~47:50) - The power of exercise (~51:00) Referenced in the episode:  - Follow Attia on Instagram (@peterattiamd) - Listen to his podcast, The Peter Attia Drive  - Check out his website (https://peterattiamd.com/)  - Pick up his book, Outlive: The Science of Art & Longevity  - Take his class on MasterClass (https://www.masterclass.com/series/science-for-a-longer-better-life) - Watch the trailer for his class on MasterClass (youtube.com/watch?v=f_Mz095swls&feature=youtu.be)   We hope you enjoy this episode, and feel free to watch the full video on YouTube! Whether it's an article or podcast, we want to know what we can do to help here at mindbodygreen. Let us know at: podcast@mindbodygreen.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

Broadcast from KSQD, Santa Cruz on 11-13-2025: Dr. Dawn discusses a New England Journal of Medicine study examining radiation exposure from medical imaging in over 4 million children showing increased hematological cancer risk. Head and brain CTs deliver highest bone marrow doses, with under-1-year-olds receiving 20 milligrays compared to background radiation of 1 milligray yearly. The study found 3,000 cancers in 4 million children over roughly 10 years, with relative risk increasing 1.6-fold per CT scan. However, methodological flaws include combining US and Canadian cohorts with different data quality, potential reverse causation where imaging detected pre-existing cancers, and arbitrary 6-month latency assumptions are significant flaws in this study.. Despite small absolute risk increases given low baseline cancer rates, she encourages parents to question necessity of repeat scans and request alternatives like MRI when appropriate. She reports on cutting-edge CRISPR therapy using lipid nanoparticles to deliver molecular scissors targeting the ANGPTL3 gene controlling LDL cholesterol production. Recent setbacks in several other CRISPR trials raise issues for unexplained liver toxicity. Concerns include off-target gene editing effects and partially repaired DNA creating mutated proteins triggering autoimmune reactions. Dr. Dawn emphasizes restricting gene therapy to life-threatening genetic diseases with no alternatives until safety improves. Stanford scientists used AI model Evo trained on 9 trillion gene samples to design 300 new bacteriophages from scratch, with 16 phages successfully killing E. coli bacteria. AI tools now predict protein structures, design custom drugs, create antivenoms, invent antibiotics, and break down PFAS forever chemicals. The research represents evolution through computation and requires guardrails on AI's ability to manipulate biological structures. An emailer shares the Rosencare model where hotel chain owner Harris Rosen created self-insured health coverage featuring direct provider contracting, imaging facilities charging one-third to one-half traditional costs, transparent pharmacy benefit management, and zero or $5 primary care copays. Employees receive proactive screening for colonoscopies, mammograms, cholesterol, diabetes, and hypertension during clinic visits. Ninety percent of medicines including insulin cost nothing, with remaining drugs $0-25, and hospital admissions cost flat $750. The model saved $600 million while providing superior preventive care by eliminating insurance middlemen and focusing on early chronic disease detection when 75-85% of costs originate. Dr. Dawn explains abdominophrenic dyssynergia causing bloating unrelated to gas or food. The diaphragm descends and abdominal wall muscles relax, pushing organs forward after meals. CT scans showed lettuce-related bloating involved no intestinal gas changes but demonstrated this abnormal muscle reflex. Randomized trials showed biofeedback training with chest-lifting and abdominal wall contracting exercises before and after eating for four weeks improved symptoms 66%. She warns that constant bloating in postmenopausal women unrelated to eating requires ovarian cancer screening. She discusses how genes drive personality using dopamine receptor gene DRD4 polymorphisms as an example. The 7-repeat variant present in 48% of Americans creates receptors binding dopamine poorly, associating with ADHD, pathological gambling, alcoholism, drug dependence, and bulimia, plus personality traits of novelty-seeking, impulsiveness, and optimism. The 2-repeat DRD4 variant common in Asia correlates with lower anger and higher forgiveness. DRD2 variations enhance the memory of negative outcomes, creating pessimistic bias and avoidance behavior. She presents the KETO trial showing "lean mass hyper-responder phenotype" where very low-carbohydrate dieters averaging age 55 maintained LDL cholesterol of 272 for five years but showed identical coronary artery calcium scores and plaque burden as matched controls with LDL under 150. Despite extreme LDL elevation, the very low insulin levels from carbohydrate restriction prevent LDL oxidation, the inflammatory "loading" process enabling arterial damage. She concludes with unusual cancer symptom where recurrent pain in specific body locations after alcohol consumption, lasting 1-2 days, occurs in 5% of Hodgkin lymphoma patients and in other cancers when alcohol induced blood vessel dilation and inflammatory chemical release in cancer-containing lymph nodes causes pain after drinking.

Listener feedback on the PISCES trial, AHA news (including a big PCSK9i trial), beta-blockers post MI, LAAC, and post-AF ablation OAC use are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Listener Feedback Why I Believe Fish Oil's Big CV Benefit in Dialysis Patients https://www.medscape.com/viewarticle/why-i-believe-fish-oils-big-cv-benefit-dialysis-patients-2025a1000uzg PISCES trial https://www.nejm.org/doi/full/10.1056/NEJMoa2513032 II PCSK9 Inhibitor News In Global Trial, PCSK9 Inhibitor Provides Major Protection Against First CV Event https://www.medscape.com/viewarticle/global-trial-pcsk9-inhibitor-provides-major-protection-2025a1000uzp VESALIUS-CV trial https://www.nejm.org/doi/full/10.1056/NEJMoa2514428 ODYSSEY trial https://www.nejm.org/doi/full/10.1056/NEJMoa1801174 FOURIER https://www.nejm.org/doi/full/10.1056/NEJMoa1615664 Anish Koka Tweet on LDL-lowering https://x.com/anish_koka/status/1987280506937909326?s=20 III Beta-Blockers After MI and John Cleland Beta-Blockers after MI with normal EF https://www.nejm.org/doi/full/10.1056/NEJMoa2512686 REBOOT-CNIC trial https://www.nejm.org/doi/full/10.1056/NEJMoa2504735 REDUCE AMI trial https://academic.oup.com/ehjcvp/article/9/2/192/6895544?login=false ABYSS trial https://www.nejm.org/doi/full/10.1056/NEJMoa2404204 CAPITAL RCT trial https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0199347 Beta-Blockers after MI with mildly reduced EF https://pubmed.ncbi.nlm.nih.gov/40897190/ John Cleland Clinical Outlook https://www.nature.com/articles/s41569-025-01228-w IV Left Atrial Appendage Closure – The CLOSURE-AF trial Percutaneous LAAC in AF Falls Short Again in CLOSURE-AF https://www.medscape.com/viewarticle/percutaneous-left-atrial-appendage-closure-af-falls-short-2025a1000uzu Prague-17 Trial https://www.jacc.org/doi/10.1016/j.jacc.2020.04.067 OPTION trial https://www.nejm.org/doi/full/10.1056/NEJMoa2408308 V Oral AC after AF ablation – the OCEAN Trial Anticoagulation After AF Ablation: The OCEAN Trial Still Leaves Questions https://www.medscape.com/viewarticle/anticoagulation-after-af-ablation-ocean-trial-still-leaves-2025a1000v4t OCEAN Trial https://www.nejm.org/doi/full/10.1056/NEJMoa2509688 ALONE-AF trial https://jamanetwork.com/journals/jama/fullarticle/2838294 You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net

L'azienda farmaceutica statunitense Merck & Co. (nota nel resto del mondo come MSD) ha annunciato i risultati molto promettenti di un nuovo farmaco che insieme alle statine contribuisce alla riduzione del colesterolo, con i partecipanti ai test clinici che hanno visto ridursi i livelli di LDL (il “colesterolo cattivo”) fino al 60 per cento in modo stabile per un anno. Ma che cosa rende “cattivo” o “buono” il colesterolo? E quella storia dei limiti cambiati anni fa per vendere più farmaci è vera? È tempo di una guida rapida. Ci spostiamo poi nell'Artico per una scoperta cosmica, eppure molto terrestre, che potrà aiutarci negli studi sul riscaldamento globale. Infine, ci occupiamo di multilinguismo e mente giovane. ⁠⁠⁠⁠⁠⁠⁠⁠Il link per abbonarti al Post e ascoltare la puntata per intero. Leggi anche: – La pillola di Merck per ridurre il colesterolo in aggiunta alle statine dà risultati paragonabili alle iniezioni – Cattiva prevenzione. I pericoli del consumismo sanitario di Roberta Villa – Statine sconsigliate in TV – Integratori a base di riso rosso fermentato: un'analisi delle sospette reazioni avverse – La polvere cosmica rivela i cambiamenti dinamici nella copertura di ghiaccio marino dell'Artico centrale negli ultimi 30.000 anni – Gli articoli del Post sulla COP30 – Il multilinguismo protegge dall'invecchiamento accelerato Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of the Heart to Heart Podcast, Dr. Mike Hart sits down with Greg Mushen, a former tech professional turned health advocate, to discuss his incredible journey of transforming his body and lifestyle. Greg shares insights from his background growing up in a medical family and how early exposure to health experiments sparked his long-lasting interest in nutrition and fitness. He details his significant body transformation starting at age 47, the role of tracking macros and engaging in strength training, and the importance of key habits like walking 17,000 steps a day. The conversation also delves into the use of red light therapy, the science behind resistant starches, and maintaining a balanced routine without becoming overly dependent on health gadgets. Greg's shift from a tech-centric life to a health-focused one offers valuable lessons on maintaining physical and mental wellness.   Greg Mushen is a tech veteran turned health optimizer, fitness coach, and writer whose work explores the science of sustainable transformation, metabolic health, and longevity. After a two-decade career in technology, Greg redirected his analytical mindset toward understanding how data-driven habits and consistent routines can radically improve health and well-being. Connect with him on LinkedIn at @GregMushen.   Links: InBody Scale Andrew Huberman, PhD  Jocko Willink  Lane Norton    Show Notes: 00:00 Welcome back to the Hart2Heart podcast with Dr. Mike Hart 01:00 Greg's early interest in health 02:30 The turning point: realizing the need for change 03:30 Greg's transformation and Twitter journey 04:30 Key strategies for transformation 08:00 The importance of walking and daily steps 10:00 Sustaining the transformation: tools and tips 14:23 "At first, tracking my food felt like a second job. But after six weeks, it became automatic—it stopped being effort and started being just who I am." 18:30 Mindset shifts and progress tracking 22:30 The role of LDL in health 27:00 Calories in, calories out debate 30:00 Accurate weight prediction and metabolic studies 31:00 Challenges of calorie tracking and satiation 32:00 Dr. Ted Naman's approach to calorie tracking 33:00 Impact of drinking calories and fiber intake 35:00 Complex carbs and resistant starch 41:00 Benefits of red light therapy 45:30 Nicotine use and addiction 49:00 Tech background and health experimentation 53:30 Future health technologies and personal insights — The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to  cutting through the noise and uncovering the most effective strategies for optimizing health,  longevity, and peak performance. This podcast dives deep into evidence-based approaches to  hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise  protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.   Beyond health science, we tackle the intersection of public health and politics, exposing how  Policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.   Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).   If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect on social with Dr. Mike Hart: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart  

Kathleen destroys the myth that eggs are harmful, Peter talks about the benefits of Kefir, and a story about Remembrance Day in a small town in Holland. Kathleen's Deep Dive Eggs got a bad rap for years for supposedly increasing bad cholesterol.  Actually, the opposite may be true. Go figure! A published study showed eating 2 eats daily lowered LDL cholesterol. Eggs provide cholesterol without overloading the liver, allowing it to clear LDL efficiently.  So go eat some farm-fresh eggs from pasture-raised hens! Peter talks about the benefits of kefir and his experience after eating it every day for five weeks. He mentions how the schoolchildren of Oosterbeek in Holland have been placing flowers on Allied paratroopers' graves every Remembrance Day for 80 years to honour their sacrifice in WWII. Links to the articles are in this week's newsletter and blog post.   Health Declassified is brought to you by Peter Wright & Kathleen Beauvais contact us to be a guest on our show. https://HealthDeclassified.com  peter@healthdeclassified.com    kathleen@healthdeclassified.com  Get our weekly newsletter for links to articles mentioned on the show, holistic health tips and news of future guests. Subscribe here   Our Affiliate Suppliers   Science Driven Supplements - Circuguard & OxyBoost https://bit.ly/3VPzsV8 MyWayCBD https://bit.ly/4jFzmd0 BAM Metrics Exercise Equipment https://bit.ly/3SMnZom B3 Sciences BFR bands https://yakking.b3bands.me/ Touchstone Essentials https://healthdeclassified.thegoodinside.com/   Follow us on social media   Spotify                        https://open.spotify.com/show/1N3yM4lUuBYGMByhwuUDVy Facebook Group        https://www.facebook.com/groups/480434235068451 FaceBook Page                https://www.facebook.com/HealthDeclassified Twitter        X                https://x.com/HealthDeclass Instagram                https://www.instagram.com/healthdeclassified/ Telegram                https://t.me/healthdeclassifed   Here are some of the tools we use to produce this podcast. Kit for sending emails and caring for subscribers Hostgator for website hosting. Podbean for podcast hosting Airtable for organizing our guest bookings and automations.   Clicking on some links on this site will let you buy products and services which may result in us receiving a commission, however, it will not affect the price you pay.      

Fasting and intermittent fasting have been in the news in recent months. In this episode, Faiza Kalam, PhD, MD, director of the James Food, Activity Sleep and Time (FACT) Lab explains the basics and how fasting and intermittent fasting can lead to improved cholesterol, LDL and blood pressure levels and rates and help people lose weight without the use of weight-reducing drugs that can have side effects. Fasting can also help cancer patients during their treatment. “The initial research has shown there is less fatigue and better quality of life for cancer patients during chemotherapy treatment who fast,” said Kalam.

I Thought My High Cholesterol Was Genetic—Until I Went Plant-Based "I had my blood work done the day before I started the transition. My total cholesterol was 298, and my LDL was 174. In the first month of following a WFPB diet, I took 76 points off my total cholesterol and 44 points off my LDL cholesterol. The weight started coming off, and I was all in." Listen to this success story written by Joanna Mittman at forksoverknives #vegan #plantbased #plantbasedbriefing #cholesterol #wfpb ====================== Original post:  https://www.forksoverknives.com/success-stories/i-thought-my-high-cholesterol-was-genetic-until-i-went-plant-based/    Forks Over Knives Documentary: https://www.forksoverknives.com/the-film/  =========================== Forks Over Knives was founded following the release of the world-famous documentary Forks Over Knives in 2011, showing people how to regain control of their health and their lives with a plant-based diet. Since then Forks Over Knives released bestselling books, launched a mobile recipe app and maintains a website filled with the latest research, success stories, recipes, and tools to help people at every phase of their plant-based journeys. They also have a cooking course, a meal planner, a line of food products, and a magazine. Please visit www.ForksOverKnives.com for a wealth of resources.  FOLLOW THE SHOW ON: YouTube: https://www.youtube.com/@plantbasedbriefing     Spotify: https://open.spotify.com/show/2GONW0q2EDJMzqhuwuxdCF?si=2a20c247461d4ad7 Apple Podcasts: https://podcasts.apple.com/us/podcast/plant-based-briefing/id1562925866 Your podcast app of choice: https://pod.link/1562925866  Facebook: https://www.facebook.com/PlantBasedBriefing     LinkedIn: https://www.linkedin.com/company/plant-based-briefing/   Instagram: https://www.instagram.com/plantbasedbriefing/

Send us a textGood morning from Pharma Daily, the podcast that brings you the most important developments in the pharmaceutical and biotech world. Today, we delve into a series of groundbreaking changes and innovations reshaping the landscape of drug development, clinical trials, and regulatory affairs.In a major move, Pfizer has successfully outbid Novo Nordisk to acquire Metsera for $10 billion. This strategic acquisition aims to bolster Pfizer's presence in the obesity treatment market by leveraging Metsera's GLP-1 receptor agonist technology. This acquisition underscores the continuing trend of consolidation within the pharmaceutical industry, enhancing competitive market positioning and reflecting a broader quest for novel therapeutic solutions.Eli Lilly has entered into a $1.2 billion collaboration with Sangenebio to advance RNA interference (RNAi) therapeutics targeting metabolic diseases. This partnership marks a pivotal shift towards utilizing RNAi technology to silence disease-causing genes, representing significant progress in metabolic disease treatment. The focus on innovative delivery mechanisms and targeted interventions is critical for accelerating drug development and enhancing therapeutic efficacy.Onchilles Pharma's recent Series A1 funding round, securing $25 million, marks a notable advancement in oncology therapeutics. The company's focus on dual-action cancer biologics targeting the ELANE pathway offers promising insights into immune activation in solid tumors. This investment exemplifies the growing interest in biologic therapies that provide targeted cancer treatments, potentially leading to more effective options for patients.Regulatory advancements are also making headlines. Chongqing Precision Biotech has received approval for Pujiolunxi, a treatment for pediatric relapsed or refractory B-cell acute lymphoblastic leukemia (ALL), broadening therapeutic options for this challenging pediatric condition. Furthermore, Alembic Pharmaceuticals' generic version of Dasatinib tablets has gained FDA approval for Philadelphia chromosome-positive chronic myeloid leukemia, increasing accessibility to treatment.Several promising clinical trial results have emerged recently. Summit Therapeutics and Akeso Biopharma's Ivonescimab showed a 26% overall survival benefit in phase 3 trials for non-small-cell lung cancer. The potential of bispecific antibodies in combination therapies is gaining attention for its efficacy in difficult-to-treat cancers. Additionally, Regeneron's Dupixent has achieved phase 3 success in treating allergic fungal rhinosinusitis, reinforcing its role as a versatile treatment option across various inflammatory diseases.Advancements in cardiovascular therapeutics also continue to unfold. Merck & Co.'s Enlicitide Decanoate demonstrated over 50% LDL cholesterol reduction in a phase 3 study focused on atherosclerotic cardiovascular disease through PCSK9 inhibition. AstraZeneca's Baxdrostat showed significant blood pressure reduction in trials targeting treatment-resistant hypertension, highlighting the potential impact of aldosterone synthase inhibitors on cardiovascular health.The investment landscape remains robust with substantial fundraising activities such as Elephas Biosciences' $40 million Series B-2 for commercializing their live tumor profiling platform and Iambic's over $100 million series focused on AI-driven drug discovery. These investments underscore the industry's commitment to integrating advanced technologies like AI and live tumor profiling to enhance precision medicine capabilities.FDA regulatory updates are pivotal as well, notably with the decision to lift warning labels from hormone replacement therapy (HRT) products following an expert review that found previous warnings were based on misinformation regaSupport the show

When you hear the word 'carnivore', do you think of lions and bears and sharks, or humans? Steak for breakfast, chicken breasts for lunch and salmon and lamb for dinner. No veg and no carbs. This is just a typical day for someone on the carnivore diet. It's a meal plan that only allows meat, poultry, eggs, fish, seafood, dairy products and water. It's animal-based opposed to plant-based. But why are some people following this diet? And what do nutritionists think about it?当你听到“食肉者”这个词时，你会想到狮子、熊和鲨鱼，还是人类？早餐是牛排，午餐是鸡胸肉，晚餐是三文鱼和羊肉——没有蔬菜，也没有碳水化合物。这就是一个典型的“食肉饮食”者的一天。这种饮食方式只允许食用肉类、禽类、鸡蛋、鱼类、海鲜、乳制品和水——完全以动物性食物为主，与植物性饮食截然相反。但问题是，为什么会有人选择这种饮食方式？而营养学家对此又怎么看？The carnivore diet is a type of ketogenic diet. Normally the body uses glucose from carbohydrates as energy, but when there's a lack of this, the liver breaks fat down into ketones. This essentially means the body can fuel itself using fat instead of sugar. Followers of the diet may experience weight loss, especially early on. One reason for this is that protein is highly satiating, so you consume fewer calories. On top of this, cutting out sugary snacks and fizzy drinks has significant health benefits, and when our carb intake is reduced, our stored water levels fall, again helping to reduce weight.食肉饮食其实是一种生酮饮食。通常，人体会利用来自碳水化合物的葡萄糖作为能量来源，但当缺乏碳水化合物时，肝脏就会将脂肪分解为酮体。这意味着身体可以用脂肪代替糖来提供能量。遵循这种饮食的人通常在初期会出现体重下降，这部分是因为蛋白质具有很强的饱腹感，从而减少总热量摄入。除此之外，戒掉含糖零食和碳酸饮料本身就有益健康，而当碳水摄入减少时，身体储存的水分也会随之减少，从而进一步帮助减重。Nevertheless, the carnivore diet can't be described as 'balanced' by any stretch, according to health experts. In fact, the British Heart Foundation strongly opposes it, saying there is no scientific evidence that it helps weight loss in the long term, and it's lacking in essential nutrients. They say extreme diets which are low in fibre and high in fat can increase the risk of heart attacks and strokes. Saturated fat increases levels of LDL cholesterol and processed meat is high in salt which can raise blood pressure. Fibre, they say, is necessary andcounteracts all these issues, but it can only be found in 'banned foods' of the carnivore diet – fruits, vegetables, seeds, legumes and wholegrains, for example.然而，健康专家指出，食肉饮食无论如何都不能称作“均衡”。事实上，英国心脏基金会（British Heart Foundation）强烈反对这种饮食方式，认为没有科学证据表明它能长期有效减重，而且缺乏必需营养素。他们警告说，这种高脂肪、低纤维的极端饮食可能增加心脏病发作和中风的风险。饱和脂肪会提高“坏胆固醇”（LDL）的水平，而加工肉类中含有大量盐分，会升高血压。专家还指出，膳食纤维对人体是必需的，它能抵消这些风险，但纤维主要存在于食肉饮食所“禁止”的食物中——例如水果、蔬菜、种子、豆类和全谷物。On social media you'll find plenty of people showing off their muscles and claiming their brain is working better than ever after weeks of fat and eggs and butter. Influencer Paul Saladino was an advocate of the carnivore diet until he started experiencing some persistent unpleasant symptoms. Speaking on a health and fitness podcast, he recounted heart palpitations, muscle cramps and sleep disturbances. He researched the diet more and concluded it was detrimental to his health and probably "not a great thing for most humans".在社交媒体上，你会看到很多人炫耀自己的肌肉，并声称在连续几周只吃脂肪、鸡蛋和黄油之后，大脑运转比以往更好。网红Paul Saladino曾是食肉饮食的倡导者，但后来他开始出现一些持续的不适症状。在一次健康与健身播客中，他提到自己经历了心悸、肌肉痉挛和睡眠障碍。经过进一步研究后，他得出结论：这种饮食对健康有害，可能“并不适合大多数人”。Most experts recommend balance, such as the Mediterranean diet, which is full of fruits, vegetables, wholegrains and seeds – it even includes meat, fish and eggs – but everything in moderation.大多数专家仍然推荐“均衡饮食”，比如地中海饮食。这种饮食富含水果、蔬菜、全谷物和种子，也包含肉类、鱼类和鸡蛋——但一切都讲究“适量”。

What is Cholesterol and what does it do?  Why do we need to manage it and what is the difference between HDL and LDL?  Statins are some of the most prescribed medications but can have some serious side effects....

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter In this "Ask Me Anything" (AMA) episode, Peter breaks down the science of dietary fiber, moving beyond the blanket advice to "eat more fiber" to uncover what it actually does in the body and where its benefits are truly supported by evidence. He explains how different types of fiber—soluble, insoluble, viscous, and fermentable—affect digestion, satiety, weight management, and glycemic control, and compares their impact to other, more potent metabolic tools. Peter also examines how certain fibers influence lipid metabolism and cardiovascular risk, evaluates the strength of evidence for fiber's role in colorectal cancer prevention, and highlights why some individuals may not tolerate specific fibers well. The discussion concludes with practical guidance on moving past generic fiber targets toward a more strategic and personalized approach that maximizes the true benefits of fiber. If you're not a subscriber and are listening on a podcast player, you'll only be able to hear a preview of the AMA. If you're a subscriber, you can now listen to this full episode on your private RSS feed or our website at the AMA #77 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here. We discuss: Why it's time to re-examine the evidence behind dietary fiber recommendations [2:00]; Why it's hard to isolate fiber's true effects on health: the limits of nutritional epidemiology [5:45]; Defining dietary fiber: what it is, how it's digested, and why different types have different effects [8:15]; Understanding fiber properties: how solubility, viscosity, and fermentability shape its effects in the body [11:15]; Resistant starches explained: types, food sources, and how cooking and cooling influence their benefits [16:30]; A framework for evaluating each of the major health claims linked to fiber [19:15]; How fiber can support weight loss: mechanisms, realistic expectations, and its complementary role to broader dietary strategies [20:30]; How fiber modestly improves glycemic control by reducing glucose spikes and insulin demand [26:15]; How fiber modestly lowers LDL cholesterol and supports cardiovascular health [34:30]; How fiber compares to other available tools and strategies for managing lipids, blood sugar, and weight [42:00]; Fiber's role in colon cancer prevention: mechanisms, evidence, and limitations [45:30]; Is fiber necessary for colon cancer prevention in otherwise healthy individuals? [53:30]; Why some people have adverse reactions to certain types of fiber, and how to manage them [56:00]; A general strategy for dietary fiber: combine multiple fiber types through whole foods and supplements [58:45]; Why total fiber intake is more important than the ratio of soluble-to-insoluble fiber [1:02:45]; The optimal timing and context for consuming fiber to maximize blood sugar control and metabolic benefits [1:05:00]; How food processing affects the functional properties of fiber, the differences between supplement forms and natural sources, and why whole foods generally remain the best option [1:06:45]; Fiber's potential to interfere with medication absorption [1:09:30]; How to safely increase fiber intake: ramp up gradually and stay hydrated [1:12:00]; Final takeaway on fiber: modest benefits, strong rationale, low downside [1:13:00]; Peter's carve-out: lessons and inspiration from the Acquired podcast [1:14:30]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

Sen. Jeanne Shaheen of New Hampshire, one of the Democrats who joined Republicans to advance a funding measure to potentially end the government shutdown, joins "CBS Mornings" to discuss the vote that has divided her party. Shaheen placed blame on President Trump and Republicans regarding health care costs, which has been at the center of the shutdown and said "we're going to live to fight another day" as the new agreement would guarantee a vote on extending Affordable Care Act subsidies. The drug maker Merck says it's developed a new daily cholesterol pill that can dramatically lower LDL, or bad cholesterol. CBS News medical contributor Dr. Celine Gounder explains what to know. The Centers for Disease Control and Prevention is investigating more than a dozen cases of infant botulism tied to the formula brand ByHeart, prompting a voluntary recall of the product. Officials say there have been 13 cases across 10 states since August. No deaths have been reported. FDA commissioner Dr. Marty Makary joins "CBS Mornings" to discuss the agency's announcement Thursday that boxed warnings will be removed from many estrogen products used for hormone therapy, a treatment that helps alleviate the symptoms of menopause. CBS News contributor David Begnaud went to San Diego in Southern California to meet a remarkable veteran who just turned 100. The Home Depot Foundation, and a group of employee volunteers stepped up to honor his legacy with an incredible surprise — a complete landscape makeover. (Sponsored by The Home Depot Foundation) Actor Josh Brolin and director Edgar Wright talk about the highly anticipated movie, "The Running Man," based on Stephen King's novel. Brolin talks about his role. The two also discuss working with Glen Powell and King. To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices

Cardiovascular disease is the No. 1 killer of women nationwide, yet during midlife—the crucial time for prevention—many women fall out of regular medical care.Host Dr. Rachel Pope is joined by Dr. Lisa Larkin, an internal medicine and women's health expert and founder of Ms. Medicine. They discuss why women's cardiovascular risk spikes around menopause and what you can do about it now.The Midlife Risk SpikeDr. Larkin highlights a failure in the healthcare system: women aged 40 to 60 often receive the least medical care, right when prevention is most critical.The perimenopausal transition causes rapid and significant metabolic changes: Cholesterol rises and HDL protection declines. Development of insulin resistance. Increase in visceral fat (the "risky fat" around organs), which is a marker for cardiovascular disease.Standard risk tools often underestimate risk in women because they don't account for sex-specific factors like adverse pregnancy outcomes (preeclampsia, gestational diabetes). Women are also often allowed to run higher blood pressures, missing opportunities for early intervention.Management & The "Missed Boat" QuestionDr. Larkin stresses that Body Composition is more important than BMI, as most women gain risky visceral fat during this time. She recommends tracking body composition annually.For women in their mid-60s who ask if they've missed the boat on prevention or Hormone Therapy (HT): Assessment is Key: Dr. Larkin performs a highly individualized assessment, often utilizing a Coronary Calcium Score to check for established plaque. If Risk is Low: A patient with perfect health metrics and a Calcium Score of zero may still be a candidate for HT to treat symptoms and support bone health. If Risk is High: The priority is to aggressively fix every single risk factor (hypertension, elevated lipids) before considering hormones, as established plaque may carry more risk with estrogen.Dr. Larkin emphasizes that women must be their best advocates because the healthcare system is currently failing to provide the comprehensive care needed during this pivotal stage of life.

Send us a textDr. Koren joins Kevin Geddings to report live from the American Heart Association meeting in New Orleans with fresh results on LDL lowering, prevention, and the future of gene editing for cholesterol. They discuss the excitement of big meetings like the AHA and how results can even surprise the investigators that were working on a study.Note: Dr. Koren refers to CRISPR Therapeutics, a company developing gene-based cholesterol lowering technologies. CRISPR-Cas9 is also the general name of a gene editing technique.Be a part of advancing science by participating in clinical research.Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.comListen on SpotifyListen on Apple PodcastsWatch on YouTubeShare with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released.Follow us on Social Media:FacebookInstagramX (Formerly Twitter)LinkedInWant to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.comMusic: Storyblocks - Corporate InspiredThank you for listening!

This week on The Diet Obsessed Podcast, I cover a variety of fascinating topics in my regular segments, including:How to get through difficult mental health daysCan Brazil Nuts lower LDL?Does Todd from RHSLC hate his wife Bronwyna after stealing the cherry from her icecream Sundae and so much more!In this week's podcast review, I highlighted the topic of "Diet Culture in China" as discussed on The Juicy Scoop Podcast with host Heather McDonald.  Heather invited guest and comedian Jiayoung Summers who talked about the challenges, discrimination and fat phobia she faced trying to be an actress in China and it's an absolutely fascinating discussion!  If this interests you, subscribe to Craving More or Craving More VIP premium content here: linktr.ee/thedietobsessedpodcast.Don't forget to leave a rating and review — it really helps the show grow!Follow along for more on Instagram: @thedietobsessedpodcast | @veronica.santarelliSupport the show

AI isn't just transforming how we work; it's quietly revolutionizing how we eat, move, sleep, and age. From smart devices that detect stress before you feel it to algorithms that predict illness years in advance, technology is giving us the tools to understand our bodies like never before. But beneath all the hype, what really matters is how we use that data to live better, not just longer.In this episode of The Wellness Algorithm, we are joined by Dr. Marcus Ranney, longevity physician. Together, we dive into the new frontier where biology meets technology, exploring how AI is reshaping fitness, nutrition, and recovery to make wellness deeply personal and preventive. We talk about what true biohacking means, why small daily choices matter more than expensive gadgets, and how science is helping us extend not just our lifespan but our healthspan. Dr. Ranney explains how AI is becoming our health ally, decoding everything from sleep quality to metabolic patterns, and how even the simplest changes like improving sleep or reducing stress can biohack your body for better energy, focus, and longevity.To help you start your own data-led wellness journey, here are some core tests and metrics he recommends for personalized health insights:Metabolic Health Tests: Fasting blood sugar, fasting insulin, HbA1c, and a full lipid profile (HDL, LDL, triglycerides).Micronutrient Panels: Vitamin D3, Vitamin B12, Iron, Magnesium, Zinc, Selenium, and Albumin.Inflammation Markers: CRP and Cortisol to assess chronic stress and systemic inflammation.Gut Health Tests: Microbiome and saliva tests to measure bacterial diversity and gut balance.Wearable Metrics: Heart rate variability, sleep tracking, and continuous glucose monitoring for real-time feedback.This episode isn't about chasing perfection or becoming robotic; it's about learning to use technology to understand yourself better. You'll walk away with practical tools, a new perspective on wellness, and a glimpse of how AI can help you stay healthier, longer while keeping your humanity at the center of it all.For a transcript of this show, go to https://wellnesscurated.life/biohacking-with-ai-the-future-of-fitness-nutrition-longevity-2/Leave a review

"Organic produce isn't necessarily not sprayed with pesticides. There's different types of pesticides. They just aren't allowed to use synthetic pesticides. Sometimes they can be even more toxic. Sometimes they have to use larger amounts because they're less effective especially given the cost difference between organic and non-organic, I don't see that it's really warranted for something" - Dr. Matthew Nagra Many people still believe that what they eat, how they live, their experiences, and even who they share their life with has no impact on their physical health. Today's guest is out to dispel that. Dr. Matthew Nagra is a Naturopathic Physician, and in case you're wondering if a Naturopathic Physician is a real doctor, Dr. Matthew Nagra is a health practitioner who treats people holistically. He follows a scientific and evidence-based approach to treating ailments.  Dr. Matthew Nagra practices Integrated Health in Vancouver, BC. He has a BSc in Microbiology from the University of Victoria and completed his ND training at the Boucher Institute. He has been vegan for over 10 years, is certified in plant-based nutrition through the T. Colin Campbell Center for Nutrition Studies. He regularly shares information regarding nutrition and health across his social media pages. Learn how to live healthier as you listen to this episode with Dr. Matthew Nagra.  What we discuss in this episode:  First things first, Dotsie shares 3 things she learned from her book-writing retreat What does a Naturopathic Doctor look for when a patient comes for evaluation compared to what a traditional doctor does? The impact of the food you eat, especially dairy products, when you have asthma Dr. Matthew Nagra talks about what he learned from the nutrition debates in school and the studies on saturated fat, LDL, collagen, etc. Refined sugar vs. fruits – What to do when sugar cravings hit  What does raw veganism mean, and how does it relate to a healthy diet? With book recommendation - Becoming Raw: The Essential Guide to Raw Vegan Diets, and Becoming Vegan, both by Brenda Davis Do you know the massive difference between butter and olive oil? How much sodium does your body need if you are healthy? What you need to know about organic food, non-organic food, and GMO The upside and downside of eating eggs and plant-based sources of choline Watch Dr. Matthew Nagra's debates with carnivores: Vegan vs. Carnivore Debate: Saturated Fat and LDL-Cholesterol and Debating LDL-Cholesterol, Saturated Fat, and CVD with a Carnivore Connect with Dr. Matthew Nagra: Website - https://drmatthewnagra.com/ Instagram - https://www.instagram.com/dr.matthewnagra/ Facebook - https://web.facebook.com/dr.matthewnagra/ Twitter - https://twitter.com/drmatthewnagra   Click the link below to support the FISCAL Act https://switch4good.org/fiscal-act/ Share the website and get your resources here https://kidsandmilk.org/ Send us a voice message and ask a question. We want to hear from you! Switch4Good.org/podcast Dairy-Free Swaps Guide: Easy Anti-Inflammatory Meals, Recipes, and Tips https://switch4good.org/dairy-free-swaps-guide SUPPORT SWITCH4GOOD https://switch4good.org/support-us/ ★☆★ JOIN OUR PRIVATE FACEBOOK GROUP ★☆★  https://www.facebook.com/groups/podcastchat ★☆★ SWITCH4GOOD WEBSITE ★☆★ https://switch4good.org/ ★☆★ ONLINE STORE ★☆★ https://shop.switch4good.org/shop/ ★☆★ FOLLOW US ON INSTAGRAM ★☆★ https://www.instagram.com/Switch4Good/ ★☆★ LIKE US ON FACEBOOK ★☆★ https://www.facebook.com/Switch4Good/ ★☆★ FOLLOW US ON TWITTER ★☆★ https://twitter.com/Switch4GoodOrg ★☆★ AMAZON STORE ★☆★ https://www.amazon.com/shop/switch4good ★☆★ DOWNLOAD THE ABILLION APP ★☆★ https://app.abillion.com/users/switch4good

Send us a textThe body keeps the score, but it also leaves clues—and midlife is when those clues get loud. I share a clear, data-backed path through perimenopause: the first strange symptoms, the shrugged-off labs, and the moment I decided to stop tolerating discomfort and start tracking what mattered. If you've been told “you're fine” while your hair breaks, your mood swings, your jeans won't zip, and your LDL creeps up, this conversation hands you a roadmap.We unpack the real turning points: timing hormone tests to the luteal phase and discovering near-zero progesterone, starting targeted HRT and monitoring results, and replacing performative cardio with short, intentional strength training to protect bone density and rebuild lean mass. I talk through raising protein, prioritizing recovery, and the overlooked variable that changed my labs—reviewing long-term psychiatric medication that can elevate LDL, then tapering safely with medical guidance. Finally, I demystify peptide therapy: what it is, how to vet a provider, why labs matter before and after, and what shifted for me when I paired peptides with smarter training and a cleaner med list.This is a practical, compassionate guide for women who want to feel strong, clear, and in charge during perimenopause. You'll hear the exact steps I took, the questions I asked, and the metrics I watched as my LDL dropped from 140 to 111 and my energy and composition improved. No quick fixes, no shame—just a precise stack and persistent self-advocacy. If you're ready to trade confusion for a plan, press play, share this with a friend who needs it, and then subscribe and leave a review to help more women find this resource. What's the first question you'll ask your doctor this week?To book a FREE discovery call with Dr. Harte, click the link below:https://calendly.com/drharte/free-discovery-call-w-dr-harteSupport the show#thetruthaboutaddiction#sobriety#the12steps#recovery#therapy#mentalhealth#podcasts#emotionalsobriety#soberliving#sobermindset#spirituality#spiritualgrowth#aa#soberlife#mindfulness#wellness#wellnessjourney#personalgrowth#personaldevelopment#sobermovement#recoveroutloud#sobercurious#sobermoms#soberwomen#author#soberauthor#purpose#passion#perspective

The Truth About Cholesterol, LDL, and Plaque Regression with Dave Feldman | Lean Mass Hyper-Responder Research Explained What if everything you've been told about cholesterol and heart disease is incomplete — or even wrong? In this eye-opening episode of The Coach Debbie Potts Show, I sit down with Dave Feldman, engineer turned citizen scientist, founder of Own Your Labs and The Citizen Science Foundation, and the mind behind the Lean Mass Hyper-Responder (LMHR) study and the groundbreaking Keto-CTA trial on plaque progression and regression. We unpack the latest findings from Dave's multi-platform coronary imaging study — comparing HeartFlow, QAngio, Cleerly, and expert readouts — to explore how some individuals with very high LDL cholesterol and low inflammation show no increase in plaque and, in some cases, true regression. You'll learn:

“When your client says their body changed overnight, she's not exaggerating.” - Dr. Jessica DrummondSo many women arrive in perimenopause or menopause feeling blindsided by the changes in their bodies. They're exercising, eating well, and they might even be using hormone replacement therapy (HRT), but no matter what they do, they're noticing weight gain around the middle, higher cholesterol, or shifts in their blood sugar. It can be discouraging for both the client and for us as practitioners when all the usual tools stop working. But these changes are not about willpower or doubling down. They're about physiology.During the menopause transition, the body goes through a true metabolic shift. Even women who seem to be perfectly healthy can experience significant changes in body composition, energy, and cardiovascular health. Research shows that each year of the menopause transition brings about a 1.7% increase in visceral fat and that LDL cholesterol can rise by up to 12%. Understanding how and why these physiological changes happen is the key to better supporting our midlife clients with compassion, structure, and confidence.Today, I'm breaking down everything about metabolism in midlife. I'm sharing the key findings from the SWAN study, how hormones, insulin resistance, and SHBG work together to influence weight, blood sugar, and energy, practical strategies for assessing and supporting clients through these changes, integrating the Confidence in Complexity framework for long-term results, and more.Enjoy the episode, and let's innovate and integrate together!---Learn more or watch the video version of this conversation at https://integrativewomenshealthinstitute.com/the-metabolic-shift-helping-women-clients-with-weight-gain-blood-sugar-and-cholesterol-in-midlife/.Connect with me and access our entire platform at IntegrativeWomensHealthInstitute.com (https://integrativewomenshealthinstitute.com/). Find and follow us @integrativewomenshealth on YouTube (https://www.youtube.com/@integrativewomenshealth) and Instagram (https://www.instagram.com/integrativewomenshealth/).

Most people are told: your cholesterol is high, here's a statin, especially if it's high LDL. End of discussion.But what if that prescription isn't always necessary? What if there are tests and questions that could completely change the outcome?In this episode, we dive into the truth about statins and diabetes, the benefits, the risks, and the controversies you rarely hear about. You'll also hear Mary's story, how she was nearly put on statins but, with the right evidence and one extra test, discovered she didn't need them at all.For show notes and resources, please visit: https://Type2DiabetesTalk.comTo share your questions and suggestions, leave us a voice message or email at: https://Type2DiabetesTalk.com/messageExplore our proven programs and services, visit: https://Type2DiabetesTalk.com/programsSubscribe to our free weekly newsletter for podcast updates, valuable nutrition tips and more: https://Type2DiabetesTalk.com/subscribe

The (Almost) Effortless Daily Habit That Can Lower Cholesterol, Boost Brain Health Drinking tea daily can lower LDL cholesterol, support heart health, and may help reduce brain lesions linked to dementia. Tea also filters heavy metals from water, offers L-theanine and is more moderate in caffeine than coffee. Listen for details. Written by Dana Hudepohl at forksoverknives #vegan #plantbased #plantbasedbriefing #tea #greentea #dementia #heavymetals #cholesterol #brainhealth ====================== Original post:  https://www.forksoverknives.com/wellness/effortless-habit-lower-cholesterol-boost-brain-health-with-tea/    Forks Over Knives Documentary: https://www.forksoverknives.com/the-film/  =========================== Forks Over Knives was founded following the release of the world-famous documentary Forks Over Knives in 2011, showing people how to regain control of their health and their lives with a plant-based diet. Since then Forks Over Knives released bestselling books, launched a mobile recipe app and maintains a website filled with the latest research, success stories, recipes, and tools to help people at every phase of their plant-based journeys. They also have a cooking course, a meal planner, a line of food products, and a magazine. Please visit www.ForksOverKnives.com for a wealth of resources.  FOLLOW THE SHOW ON: YouTube: https://www.youtube.com/@plantbasedbriefing     Spotify: https://open.spotify.com/show/2GONW0q2EDJMzqhuwuxdCF?si=2a20c247461d4ad7 Apple Podcasts: https://podcasts.apple.com/us/podcast/plant-based-briefing/id1562925866 Your podcast app of choice: https://pod.link/1562925866  Facebook: https://www.facebook.com/PlantBasedBriefing     LinkedIn: https://www.linkedin.com/company/plant-based-briefing/   Instagram: https://www.instagram.com/plantbasedbriefing/  

In this follow-up to his deep dive on protein, Darin exposes the other side of the protein story: where your food comes from, what's really in it, and how the system itself affects your health, the planet, and the animals. From factory farm contamination to antibiotic resistance, industry lobbying, and why plants still win on every level — Darin breaks down the research, ethics, and environmental data so you can make conscious choices that fuel a truly SuperLife. What You'll Learn [00:00] Welcome + sponsor message: plastic waste, conscious products, and Bite Toothpaste [02:47] Introduction — the real protein conversation continues [03:00] The source of your food matters more than macros [03:10] Contamination, ethics, and the reality of factory farming [03:30] Stewardship vs. dominion — a call for responsibility [04:01] EPA data: confined animal operations and environmental chaos [05:00] Foodborne illness: salmonella, E. coli, and what contamination really means [05:57] Antibiotics, resistance, and hormones in animal agriculture [06:42] Persistent pollutants (PFOAs) showing up in food and milk [07:10] How animal feed (soy and corn) drives ecological damage [07:57] USDA marketing boards + industry lobbying against plant alternatives [08:38] Darin's 17 years vegan — data and lived experience [09:00] The numbers: amino acids, LDL, fat swaps, and longevity [09:47] Common plant-based protein myths answered [12:59] Patreon message — upgrade your operating system and join the tribe [14:03] The cancer connection: processed and red meat research [14:47] Iron, B12, and what vegans actually need to know [15:37] Soy, testosterone, and thyroid myths debunked [16:08] Protein quality: why mixing plant foods covers all bases [16:31] Feeling better on moderate meat? Understanding the trade-offs [17:18] Substitution data: even small swaps improve health outcomes [17:57] Processed vs. ultra-processed: why Beyond Meat isn't the enemy [18:09] Environmental impact: why beef's footprint dwarfs plant protein [19:05] Food miles myth — what you eat matters more than distance [19:29] Cost and accessibility: the cheapest protein sources are plants [20:08] Contamination and antibiotic resistance rising annually [21:03] Anti-nutrients and the myth of plant dangers [21:47] Real-world evidence: fiber, polyphenols, and legume-based longevity [22:00] Final recap — all essential amino acids come from plants [22:17] Strongest evidence: plant protein wins ethically, environmentally, and scientifically Thank You to Our Sponsors: SuperLife Patreon: Go towww.patreon.com/DarinOlien and sign up to start changing your life today Bite Toothpaste: Go to trybite.com/DARIN20 or use code DARIN20 for 20% off your first order. Connect with Darin Olien: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences Platform & Products: superlife.com Key Takeaway "All plants contain all essential amino acids. The more you swap red meat for plants, the longer, stronger, and cleaner your life becomes."

Heart disease is still our number one killer, even though 50 million Americans have been prescribed a cholesterol-lowering statin. Cardiologists pay a lot of attention to cholesterol in all its variety: total cholesterol, LDL, HDL, VLDL. Even blood fats like triglycerides and lipoprotein a [Lp(a)] are getting some attention. What else do you need to […]

I used to think of fiber as just “good for digestion,” but it turns out this single nutrient can lower cholesterol as powerfully as a statin—and do so much more for your brain, gut, and longevity. In this minisode of The Neuro Experience, I sit down with Dr. Rupy Aujla — NHS doctor, author, and founder of The Doctor's Kitchen — to break down the science behind fiber and why it's one of the most underrated tools for preventing heart disease and inflammation. This episode features highlights from our full conversation, which premiered August 5th, 2025. Watch the full episode here → https://www.youtube.com/watch?v=Jay-Sg2sg6s Connect with Dr. Rupy Aujla: Website: The Doctor's Kitchen Instagram: @doctors_kitchen Books: The Doctor's Kitchen & Eat to Beat Illness *** Topics discussed: 00:18 – The TikTok “fiber maxxing” trend explained 00:42 – How to transition from low-fiber to high-fiber safely 01:02 – How fiber binds cholesterol and removes it from the body 01:26 – Feeding your gut microbes: the real reason fiber matters 02:10 – What short-chain fatty acids do for inflammation and longevity 03:00 – How fiber increases LDL receptor activity in the liver 03:42 – How 60 days of high-fiber eating lowers ApoB and LDL 04:03 – The “Portfolio Diet” that rivals statins 05:08 – The best fiber-rich foods: oats, barley, soy, nuts, seeds 06:14 – What to know about oats, glyphosate, and processing 07:16 – The perfect high-fiber breakfast recipe 07:53 – How food can match statin effects (and go beyond) 09:10 – The one daily change to reduce heart attack and stroke risk 09:26 – Dr. Rupy's B.B.G.S. formula for everyday health 10:13 – How fiber diversity transforms cholesterol and gut health *** I'm Louisa Nicola — clinical neurophysiologist — Alzheimer's prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer's risk — and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices

High cholesterol no matter what you eat? You could have familial hypercholesterolemia - a genetic condition that causes very high LDL (“bad”) cholesterol levels even with a healthy lifestyle. In this episode, dietitian Teresa Wagner explains what familial hypercholesterolemia (or FH) is, why it happens, and what you can do to protect your heart.

I recently had an ApoB test and am surprised that it isn't lower than it is.  Can you explain?I have an ascending thoracic aortic aneurysm.  How can I keep it from enlarging?Why are you against whole-body scans? Aren't they helpful?Can I take magnesium L-threonate while also taking magnesium glycinate?

Will Truheight vitamins really make your kids grow?Where can I learn more about complementary medicine and nutrition?The balls of my feet are sore along with my toes. Is this a vitamin deficiency?

The Real Truth About Cholesterol, Heart Disease & Cardiovascular Health SUMMARY What if your cholesterol isn't trying to kill you—it's trying to protect you? In this solo deep-dive, Coach Debbie Potts breaks down the outdated cholesterol myths and reveals the root-cause truth behind cardiovascular disease. Drawing from the work of Dave Feldman, Dr. Ben Bikman, Dr. Paul Mason, Ivor Cummins, and Dr. William Davis, Debbie explains why heart disease is an inflammatory, metabolic, and endothelial problem—not a cholesterol problem. Learn which markers truly predict risk, how to interpret your labs beyond LDL, the role of genetics and epigenetics, and what it really takes to reverse plaque and rebuild a resilient metabolism. If you're ready to move beyond fear and finally understand your cardiovascular health through the lens of functional, ancestral, and root-cause medicine, this episode is your roadmap. KEY TAKEAWAYS LDL isn't "bad"—oxidized, inflamed LDL in a damaged arterial wall is. Heart disease = terrain dysfunction: insulin resistance, oxidative stress, mitochondrial damage, and loss of nitric oxide. ApoB + inflammation predict risk far better than total cholesterol. Context matters: High LDL in a low-inflammation, insulin-sensitive body ≠ the same risk as in a high-inflammation body. Saturated fat isn't the enemy; oxidized seed oils and sugar are. You can't out-supplement poor habits. Sleep, stress regulation, circadian alignment, and daily movement build vascular resilience. Plaque can stabilize or regress when you heal the root causes. The WHOLESTIC Method™ integrates nutrition, movement, sleep, stress, digestion, hydration, and happiness to rebuild your health from the inside out. TESTS & TOOLS MENTIONED - talk to your provider! ApoB (< 80 mg/dL optimal) LDL-P (< 1,000 nmol/L) Triglyceride : HDL ratio (< 1) hs-CRP (< 0.5 mg/L) Lp(a) (< 30 mg/dL) Fasting Insulin / HOMA-IR (< 5 µIU/mL / < 1.0) Coronary Artery Calcium (CAC) Score (0 = clean) CCTA / Cleerly AI Analysis for plaque composition Carotid IMT, Omega-3 Index, Homocysteine, Vitamin D + K2

Today, we're tackling a question that comes up often in peptide, weight loss, and nutrition clinics: why does one person see great results with semaglutide, while another responds better to tirzepatide—or even retatrutide? If you want to support what we do, head over to our Partners Page. You'll find some amazing brands we trust—and by checking them out, you're helping us keep the podcast going. https://pepties.com/partners/ All three peptides target the incretin system, but they act in slightly different ways—and those differences can dramatically affect outcomes. Let's start with the basics. Semaglutide is a GLP-1 (glucagon-like peptide-1) receptor agonist. It mimics the gut hormone GLP-1, which increases insulin when blood sugar is high (to help lower blood sugar), suppresses glucagon (which also decreases blood sugar), and slows gastric emptying. It also enhances satiety—so you feel full longer and eat less. Tirzepatide is a dual agonist, acting on both GLP-1 and GIP receptors. GIP—glucose-dependent insulinotropic polypeptide—also helps with insulin secretion to lower blood sugar, increases fat metabolism, and may reduce some of the GI side effects seen with GLP-1 alone. Retatrutide, the newest in the lineup, is a triple agonist that targets GLP-1, GIP, and glucagon receptors. Retatrutide lightly activates the glucagon receptor while strongly activating GLP-1 and GIP receptors, which help regulate blood sugar and boost insulin secretion. This keeps blood sugar stable—or even improves it. Beyond blood sugar, glucagon also ramps up metabolism and calorie burning. By gently engaging glucagon receptors, retatrutide can increase energy expenditure and support fat loss without triggering large blood sugar spikes. So how do you decide which one might work best? Let's walk through common clinical situations. Patients with Hypothyroidism Let's talk about hypothyroidism. People with hypothyroidism often have slower metabolism, making weight loss more difficult even with a balanced diet. Low thyroid hormone levels slow calorie burning and energy use, so weight gain can occur more easily. For these patients, semaglutide is a reliable starting point—it helps regulate appetite and caloric intake. If progress plateaus, tirzepatide or retatrutide may provide an edge by boosting energy expenditure and fat oxidation, essentially "jump-starting" a slower metabolism. Patients with PCOS (Polycystic Ovary Syndrome) What about patients with PCOS (polycystic ovary syndrome)? Insulin resistance is common in PCOS, often leading to higher androgen levels (e.g., testosterone) and symptoms like irregular periods, acne, and excess hair growth. Hormonal changes also affect appetite-regulating hormones, increasing hunger and cravings. Both GLP-1 and dual agonists have proven effective in managing metabolic and reproductive aspects of PCOS. Typically, we start with semaglutide to improve weight, insulin sensitivity, androgen levels, and menstrual regularity. After a few months, if weight loss plateaus or cravings remain high, we may switch to tirzepatide. The added GIP activity enhances fat metabolism, insulin control, and may further support hormone regulation and ovulation. The key is starting with what's well-studied and tolerated, then stepping up if additional metabolic or reproductive support is needed. Type 2 Diabetes (T2DM) The next medical condition I'd like to talk about is type 2 diabetes (T2DM). Weight gain in T2DM often stems from insulin resistance. Cells don't respond effectively to insulin, prompting the pancreas to relelase more. High insulin levels encourage fat storage, particularly around the abdomen, while elevated blood sugar can increase hunger and cravings. Some diabetes medications, like insulin or sulfonylureas (e.g., glipizide or glyburide), can also contribute to weight gain. All three drugs lower blood sugar and promote weight loss, but tirzepatide currently shows the strongest combined A1c reduction (average blood sugar over the past 2 to 3 months) and weight loss. GIP and GLP-1 work together to enhance insulin response more effectively than GLP-1 alone. Retatrutide is in phase 3 trials, with potential FDA approval as early as 2027. Its glucagon receptor activity may offer additional glucose regulation and energy expenditure benefits. Patients with >15% Weight Loss Goals Okay, let's talk about weight loss goals and how this ties into the decision process for choosing a weight loss medication. For those patients looking to lose more than 15% of their total body weight, tirzepatide or retatrutide are likely to deliver greater results. Clinical data show semaglutide can achieve up to 15% total weight loss while tirzepatide can achieve up to 22% and retatrutide up to 24%. That said, semaglutide remains a highly effective option for weight loss. However, if progress begins to plateau, transitioning to a dual or triple agonist may help restart weight loss and push past that plateau. Pre- and Postmenopausal Women What about peri- and postmenopausal patients? Hormonal shifts during perimenopause and menopause slow metabolism and can increase cravings. Declining estrogen promotes abdominal fat storage and affects appetite-regulating hormones. Semaglutide helps with appetite control and gradual fat loss, while tirzepatide's GIP activation can further support fat metabolism when estrogen levels drop. Patients with Heart Disease or High Cholesterol The last group of patients I'd like to discuss is patients with heart disease (e.g., heart failure, stroke, heart attack, or even atherosclerosis) or people with high cholesterol. Semaglutide has the strongest cardiovascular outcomes data, reducing major adverse cardiac events by 20% and improving LDL cholesterol (bad cholesterol) and blood pressure. Tirzepatide shows promise for heart and lipid benefits, but those trials are still ongoing. For patients with prior heart attack, stroke, or severe coronary artery disease, semaglutide remains the safest evidence-backed starting point—unless intolerable side effects or weight loss resistance occur. Tolerability Now I want to switch gears a bit and talk about side effects and tolerablity of these peptides. Some patients experience stomach-related side effects like nausea, bloating, or acid reflux on semaglutide. Generally, tirzepatide tends to cause fewer GI side effects, likely due to GIP balancing GLP-1 activity in the gut. So patients struggling with nausea or other stomach-related side effects may find tirzepatide more tolerable. Just something to keep in mind. Individualizing Therapy Lastly, I want to highlight the importance of individualizing weight loss peptide treatments. There's no one-size-fits-all approach when it comes to these therapies. Clinicians should carefully consider a patient's goals, medical history, current medications, and tolerance before choosing the most appropriate option. Setting realistic expectations from the start is essential. It's important to remember that everyone's body responds differently because of factors like hormones, genetics, metabolism, gut microbiome balance, and lifestyle habits. These differences influence how effectively a peptide therapy works and how well it's tolerated. That's why ongoing monitoring and follow-up are such an important part of the process. Providers track progress, adjust dosing when needed, and switch medications if weight loss plateaus or side effects occur. The goal isn't just to lose weight quickly—it's to create a safe, sustainable plan that supports long-term metabolic health and helps patients feel their best. Thanks for listening to The Peptide Podcast.  If you want to support what we do, head over to our Partners Page. You'll find some amazing brands we trust—and by checking them out, you're helping us keep the podcast going. Until next time, be well, and have a happy, healthy week.

High cholesterol no matter what you eat? You could have familial hypercholesterolemia - a genetic condition that causes very high LDL (“bad”) cholesterol levels even with a healthy lifestyle. In this episode, dietitian Teresa Wagner explains what familial hypercholesterolemia (or FH) is, why it happens, and what you can do to protect your heart.

Send us a textJosh Wageman is a returning guest on our show! Be sure to check out his first appearance on episode on 869 of BBR!Josh Wageman is a Clinical Lipid Specialist with multiple doctoral degrees who formerly practiced in Endocrinology. His PhD work focused on cholesterol disturbances in Alzheimer's Disease and, although he also has a Doctorate in Physical Therapy, he is best known for his role in teaching lipid physiology.He serves as an adjunct professor at several medical programs and his goal is to help you, whoever you are, NOT have heart attacks, strokes, and dementia by explaining complicated biochemical concepts in a relatable way!Employing a smorgasbord of metaphors, pictures, and catchphrases, his latest book The Home Security System and the Lipid Neighborhood serves as a valuable reference for clinicians and non-clinicians alike, bringing refreshing relatability to complex biochemical topics. Through a lipid-lens, you'll learn, laugh, and love your way through its pages…and in the end, you'll undoubtedly add “life to your years!”Josh is active in Youth Ministries at Heritage Bible Church in Boise, Idaho, and resides there with his family. He also enjoys Crossfit, basketball, Ultimate Frisbee, and all sports that don't involve skates.Find Dr. Wageman at-Amazon- The Home Security System and the Lipid Neighborhood IG- @wagemanjoshLK- @Josh WagemanFind Boundless Body at- myboundlessbody.com Book a session with us here!

In this Facebook Live episode, Shana shares how she naturally lowered her total cholesterol by 58 points and LDL by 41 points in just 11 weeks—without statins—by addressing insulin resistance and easily adding 7 different fibers with the Feel Great System. You'll learn what causes "high" cholesterol beyond diet, how insulin and inflammation play a bigger role than fat intake, and how strategic nutrients like soluble fibers, phytosterols, and chlorogenic acid improve both lipid and glucose metabolism. What You'll Learn The real root of high cholesterol: insulin resistance and poor metabolic signaling. Why statins don't fix insulin resistance—and what they actually do. How Balance (soluble fiber matrix) supports healthy LDL, satiety, and blood sugar control. Guar gum, beta-glucans, gum arabic, citrus pectin → lower LDL, stabilize glucose, support gut microbiota. Phytosterols → reduce LDL and raise HDL. Chromium → enhances insulin sensitivity, reduces sugar cravings. Niacin → supports HDL and energy metabolism How Unimate (yerba mate extract) enhances GLP-1, focus, and fat metabolism. Chlorogenic acid → reduces LDL/triglycerides, improves insulin sensitivity, and supports mitochondrial energy. Theobromine → improves HDL/LDL ratio, boosts mood and alertness without jitters. Mate saponins and polyphenols → lower visceral fat, protect the liver, and calm inflammation How improving GLP-1 naturally helps you feel full longer, lose weight, and stabilize blood sugar. Simple lifestyle rhythms—light, sleep, meal timing—that magnify your results. Key Takeaways Fixing insulin resistance improves both cholesterol and blood sugar markers. The Feel Great System is listed in the Physician's Desk Reference (PDR) and backed by published studies. You can partner with your clinician to explore reducing or avoiding cholesterol meds as metabolic health improves. Supporting GLP-1 naturally with Feel Great can mimic some benefits of popular medications—without side effects. Products Mentioned

Hour 3 for 10/28/25 Dr. Sean O'Mara joined Drew to discuss all things sugar (4:19). Topics included: why sugar is addicting (12:13), diet soda (16:10), sugar's connection to cancer (16:10), sugar's connection to cancer (19:44), good habits (24:01), honey (27:59), RX bars (30:23), fermented foods (34:53), sports nutrition (41:23), alcohol (44:22), LDL cholesterol (47:56). Original Air Date: 10/30/24

We break down the five health numbers that forecast cardiovascular and metabolic risk and turn them into a simple plan you can act on today. Clear targets, practical measurement tips, and small habits help you lower risk and feel better fast.• why blood pressure thresholds matter and how to measure right• LDL, HDL, triglycerides and the power of ratios• diet swaps and exercise that shift lipid panels• fasting glucose versus A1C and what each reveals• quick wins to improve insulin sensitivity• why waist beats BMI for risk prediction• building muscle for long-term metabolic health• resting heart rate, HRV and recovery heart rate• a step-by-step system to track, trend and act• red flags that mean it's time to see a doctorIf you'd enjoyed today's episode, I'd love for you to share it with your friends and familyAnd if you're feeling generous, consider donating at the link provided in the descriptionFor more resources, tips, and updates, don't forget to visit our website at www.kore-fit.com and follow us on Instagram at KoreFitnessAZJoin our community and let's continue this journey together"Transform Your Life with Kore Fitness"Kore Fitness: Your path to a healthier, stronger you. Personalized training and proven results.Disclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showhttps://www.kore-fit.com

In this episode of Death Clock, Brent speaks with Dr. Nazish Sayed, a Stanford cardiologist and vascular biologist, to cut through the confusion about cholesterol, heart disease, and statins. Dr. Sayed breaks down what LDL, HDL, and ApoB really mean, why high cholesterol is more about your biology than your breakfast, and how inflammation and genetics drive plaque buildup long before symptoms appear. He explains how statins work and why their benefits far outweigh the risks for most people. It's an evidence-based exploration of one of medicine's most misunderstood topics. Hope you enjoy.

Every 80 seconds, a woman dies from heart disease — yet most still think cancer is the bigger threat. In this minisode, I sit down with Dr. Jeremy London, board-certified cardiothoracic surgeon, to unpack why women's cardiovascular risk skyrockets after menopause and how hormones, inflammation, and lifestyle choices all connect. This episode features highlights from our full conversation, which premiered July 24th, 2025. Watch the full episode here → https://www.youtube.com/watch?v=7jbvQRZgb3w Dr. London explains how declining estrogen drives visceral fat, raises cholesterol, and fuels chronic inflammation — creating a “perfect storm” for heart attacks, strokes, and even Alzheimer's. From estrogen and inflammation to cholesterol, exercise, and sleep — this conversation exposes the real science behind heart and brain health. If you've ever wondered how to protect yourself from the #1 killer of women, this episode will change how you think about prevention, hormones, and longevity. *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** I'm Louisa Nicola — clinical neurophysiologist  — Alzheimer's prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer's risk — and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Topics discussed: 00:00 – Why Women's Heart Risk Triples After Menopause 00:55 – Estrogen's Role: Anti-Inflammatory and Protective 01:45 – Weight Gain, Visceral Fat, and Inflammation 02:09 – Cholesterol, LDL, and Rising Risks Post-Menopause 02:38 – The “Perfect Storm” of Metabolic Decline 03:13 – How the Women's Health Initiative Misled Women on Hormones 03:36 – Estrogen, Brain Health, and Alzheimer's Connection 04:45 – The #1 Global Killer: Cardiovascular Disease 05:26 – What “Heart Disease” Really Means 06:00 – Cholesterol Explained: HDL, LDL, and Triglycerides 07:37 – Why ApoB Is a More Accurate Marker 09:18 – Plaque Formation and Early Intervention 10:11 – The Study That Reversed Heart Aging by 20 Years 11:24 – VO₂ Max, Zone-5 Training, and Longevity 12:16 – Resistance Training and “Muscle as the Organ of Longevity” 13:09 – Why Consistency Beats Intensity 13:57 – The Sitting Disease and Daily Movement 14:22 – The Power of Nutrition: “Your Body Is the Soil” 15:02 – Whole Foods, Processed Diets, and Alcohol 16:24 – Can Plaque Be Reversed? The Truth 17:11 – Alzheimer's and Lifestyle: Prevention Starts in Your 30s 18:19 – The Final Pillar: Sleep and Recovery 19:28 – Why Sleep Fuels Brain and Heart Health 20:12 – Which Health Pillar Matters Most for You Learn more about your ad choices. Visit megaphone.fm/adchoices

With a calcium score of zero, is there any fat in your diet?  Are there any recommended supplements for IBS?What is the safest and most appropriate dose of vitamin D3 for most seniors?

INFINITY Study on the timing of thyroid medication ingestionI have a growth near my eye that is changing in color and becoming crusty. What should I do?I've been suffering from hip pain for the last three years. Any suggestions on what to do?Could toxic exposures like mold cause conditions like low thyroid or autoimmunity?

A study published in the American Journal of Clinical Nutrition showed that eating two eggs daily lowered LDL cholesterol, while high saturated fat diets raised it Researchers found cholesterol from eggs did not raise LDL, but saturated fat from foods like bacon and sausage did, showing food context makes a major difference Eggs provide cholesterol without overloading the liver, allowing it to clear LDL efficiently and preventing artery buildup that increases heart disease and stroke risk Weekly egg intake reduced heart disease deaths by 29% and all-cause mortality by 17% in older adults, highlighting the importance of moderation for protective benefits Choosing pastured eggs, avoiding vegetable oils, and pairing eggs with nutrient-rich whole foods further boost benefits while minimizing harmful omega-6 linoleic acid (LA) intake

Dr. Jeff Graham sits down with Dr. Damon Forbes to explore the emerging concept of “lean mass hyper-responders”— fit, low-carb individuals who present with unusually high LDL levels. They unpack the physiology behind this pattern, discuss how it differs from familial hypercholesterolemia, and review new data on cardiovascular risk. The conversation offers a nuanced look at how metabolism, diet, and lipid transport intersect in precision medicine.

A Fortune 250 company in Des Moines, Iowa transformed employee health through a whole-food, plant-based lifestyle.    Discover how Gretchen Barris teamed up with PCRM and Dr. Jim Loomis to launch a 16-week wellness program at Principal Financial that helped 240 participants dramatically lower cholesterol, reverse prediabetes, lose weight, and boost energy — all for just $108 per person.   Chuck Carroll sits down with Jean McGinnis and participants like Malcolm & Suzanne Showalter who conquered migraines, reversed heart disease risk, and experienced newfound vitality. Learn how this evidence-based approach from the Barnard Medical Center and PCRM is revolutionizing corporate wellness — even in the heart of the Midwest!   What You'll Learn in This Episode - How a Fortune 250 company implemented a plant-based program on a small budget - The average 23% LDL reduction and 18% A1C improvement among participants - Why employees reported better sleep, focus, and mental health - The difference between “health care” and “sick care,” explained by Dr. Loomis - How to bring programs like this to your own workplace  

Can strength training, sprinting, and nutrition truly transform women's hormones, metabolism, and longevity? In this episode, Dr. Stephanie Estima — chiropractor, women's health expert, and founder of The Estima Method — breaks down the science of female physiology, muscle, and midlife health. We cover why walking isn't enough, how hormones shape muscle and bone, and why protein and strength training are essential “medicine” for women over 35. Expect myth-busting, practical tools, and empowering insights to help you train and live in sync with your biology. About Dr. Stephanie Estima: Dr. Estima began her career in chiropractic care, where she developed a deep interest in neuroscience, biomechanics, and the body's connection between movement and the brain. After noticing how differently men and women respond to the same health strategies, she became passionate about helping women navigate hormones, metabolism, and midlife health. Where to find Dr. Estima: Instagram: @dr.stephanie.estima Website: https://drstephanieestima.com *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Function Health: Visit https://functionhealth.com/louisa or use gift code NEURO100 at sign-up to own your health. Ketone IQ: Go to https://www.ketone.com/NEURO for 30% OFF your subscription order PUORI: Go to https://puori.com/NEURO and use the code NEURO at checkout for 20% off. AquaTru: Go to https://AquaTru.com now for 20% off (your purifier) using promo code NEURO. AquaTru even comes with a 30-day best-tasting water guarantee. Caraway: Visit https://Carawayhome.com/neuro and take an additional 10% off your next purchase. Jones Road Beauty:  Head to https://Jonesroadbeauty.com and use code NEURO at checkout. *** I'm Louisa Nicola — clinical neuroscientist — Alzheimer's prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer's risk — and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Topics discussed: 00:00 – Intro 03:14 – Reassessing Hormone Therapy in 2025 04:24 – The Rise of HRT & Social Media Awareness 05:37 – Balancing the Conversation: HRT Pros & Cons 06:42 – Lifestyle Levers That Matter More 08:05 – Why Walking Isn't Enough Exercise 10:59 – Muscle Quality & Metabolism Explained 12:29 – Type 1 vs. Type 2 Muscle Fibers 16:25 – Glucose, Muscle, and Longevity18:07 – Bone Health & Estrogen 20:33 – The Power of Impact Training 22:28 – How to Build a “Prescription for Health” 24:06 – The Zone 2 Misconception 26:29 – Progressive Overload & The “Weighted Vest” Myth 27:45 – Sample Lower-Body Workout Blueprint 34:03 – Learning Proper Squat Mechanics 35:28 – The Power of Deadlifts & Hip Hinge Movements 36:46 – Glute Bridges & Unilateral Training 38:35 – Nutrition & Midlife Metabolism 39:47 – How Hormones Change Body Composition 42:06 – Sleep, Insulin, and the Estrogen Cascade 43:59 – Strength Training as Hormone Therapy 45:06 – LDL & Visceral Fat Connection 46:04 – Fasting & Female Metabolism 47:17 – Why Aggressive Fasting Backfires for Women 50:53 – The Dark Side of Fasting Culture 53:22 – Practical Guidelines for Eating Windows 54:03 – Under-Fueling & Protein Deficiency in Women 55:09 – Appetite, GLP-1 Drugs & Metabolic Health Learn more about your ad choices. Visit megaphone.fm/adchoices

This week, Dr. Joel Kahn explores three advanced methods for cleansing the blood. He begins with apheresis, a medical technique that removes LDL cholesterol and Lipoprotein(a), and discusses new developments in access to this life-saving therapy. Dr. Kahn also breaks down two emerging treatments gaining popularity—EBOO (Extracorporeal Blood Oxygenation and Ozonation) and TPE (Therapeutic Plasma Exchange)—and how they may play a role in improving cardiovascular health. In the second half, Dr. Kahn turns to the topic of cholesterol-lowering therapies like statins, emphasizing how long-term use and individualized risk assessment matter more than online debates suggest. He highlights tools such as the Mayo Clinic Statin Decision Aid, PREVENT calculator, and Astro-CHARM calculator to help patients and practitioners make informed decisions.  Thanks to the Fresh Pressed Olive Oil Club for sponsoring this episode. Visit getfreshdrkahn.com for a special offer.

Can you really lower cholesterol with food? Dr. Michael Greger joins Chuck Carroll on The Exam Room Podcast to reveal the simple, science-backed foods and spices that can drive LDL cholesterol down—without drugs or side effects. Discover how everyday choices can protect your heart and add years to your life.   What You'll Learn in This Episode:   - Why the Standard American Diet is now the #1 cause of death in the U.S. - The truth about statins: small benefit, real risks. - How plant-based eating can reverse heart disease. - Foods that raise cholesterol: meat, dairy, eggs, coconut & palm oils. - The top foods and spices proven to lower LDL include black soybeans, apples, and garlic powder. - Why olive oil raises cholesterol on a vegan diet. - Green tea and mushrooms: health boosters, but not major LDL-reducers. - Practical tips: even one small daily change makes a big difference.