Podcasts about ldl

AI isn't just transforming how we work; it's quietly revolutionizing how we eat, move, sleep, and age. From smart devices that detect stress before you feel it to algorithms that predict illness years in advance, technology is giving us the tools to understand our bodies like never before. But beneath all the hype, what really matters is how we use that data to live better, not just longer.In this episode of The Wellness Algorithm, we are joined by Dr. Marcus Ranney, longevity physician. Together, we dive into the new frontier where biology meets technology, exploring how AI is reshaping fitness, nutrition, and recovery to make wellness deeply personal and preventive. We talk about what true biohacking means, why small daily choices matter more than expensive gadgets, and how science is helping us extend not just our lifespan but our healthspan. Dr. Ranney explains how AI is becoming our health ally, decoding everything from sleep quality to metabolic patterns, and how even the simplest changes like improving sleep or reducing stress can biohack your body for better energy, focus, and longevity.To help you start your own data-led wellness journey, here are some core tests and metrics he recommends for personalized health insights:Metabolic Health Tests: Fasting blood sugar, fasting insulin, HbA1c, and a full lipid profile (HDL, LDL, triglycerides).Micronutrient Panels: Vitamin D3, Vitamin B12, Iron, Magnesium, Zinc, Selenium, and Albumin.Inflammation Markers: CRP and Cortisol to assess chronic stress and systemic inflammation.Gut Health Tests: Microbiome and saliva tests to measure bacterial diversity and gut balance.Wearable Metrics: Heart rate variability, sleep tracking, and continuous glucose monitoring for real-time feedback.This episode isn't about chasing perfection or becoming robotic; it's about learning to use technology to understand yourself better. You'll walk away with practical tools, a new perspective on wellness, and a glimpse of how AI can help you stay healthier, longer while keeping your humanity at the center of it all.For a transcript of this show, go to https://wellnesscurated.life/biohacking-with-ai-the-future-of-fitness-nutrition-longevity-2/Leave a review

"Organic produce isn't necessarily not sprayed with pesticides. There's different types of pesticides. They just aren't allowed to use synthetic pesticides. Sometimes they can be even more toxic. Sometimes they have to use larger amounts because they're less effective especially given the cost difference between organic and non-organic, I don't see that it's really warranted for something" - Dr. Matthew Nagra Many people still believe that what they eat, how they live, their experiences, and even who they share their life with has no impact on their physical health. Today's guest is out to dispel that. Dr. Matthew Nagra is a Naturopathic Physician, and in case you're wondering if a Naturopathic Physician is a real doctor, Dr. Matthew Nagra is a health practitioner who treats people holistically. He follows a scientific and evidence-based approach to treating ailments.  Dr. Matthew Nagra practices Integrated Health in Vancouver, BC. He has a BSc in Microbiology from the University of Victoria and completed his ND training at the Boucher Institute. He has been vegan for over 10 years, is certified in plant-based nutrition through the T. Colin Campbell Center for Nutrition Studies. He regularly shares information regarding nutrition and health across his social media pages. Learn how to live healthier as you listen to this episode with Dr. Matthew Nagra.  What we discuss in this episode:  First things first, Dotsie shares 3 things she learned from her book-writing retreat What does a Naturopathic Doctor look for when a patient comes for evaluation compared to what a traditional doctor does? The impact of the food you eat, especially dairy products, when you have asthma Dr. Matthew Nagra talks about what he learned from the nutrition debates in school and the studies on saturated fat, LDL, collagen, etc. Refined sugar vs. fruits – What to do when sugar cravings hit  What does raw veganism mean, and how does it relate to a healthy diet? With book recommendation - Becoming Raw: The Essential Guide to Raw Vegan Diets, and Becoming Vegan, both by Brenda Davis Do you know the massive difference between butter and olive oil? How much sodium does your body need if you are healthy? What you need to know about organic food, non-organic food, and GMO The upside and downside of eating eggs and plant-based sources of choline Watch Dr. Matthew Nagra's debates with carnivores: Vegan vs. Carnivore Debate: Saturated Fat and LDL-Cholesterol and Debating LDL-Cholesterol, Saturated Fat, and CVD with a Carnivore Connect with Dr. Matthew Nagra: Website - https://drmatthewnagra.com/ Instagram - https://www.instagram.com/dr.matthewnagra/ Facebook - https://web.facebook.com/dr.matthewnagra/ Twitter - https://twitter.com/drmatthewnagra   Click the link below to support the FISCAL Act https://switch4good.org/fiscal-act/ Share the website and get your resources here https://kidsandmilk.org/ Send us a voice message and ask a question. We want to hear from you! Switch4Good.org/podcast Dairy-Free Swaps Guide: Easy Anti-Inflammatory Meals, Recipes, and Tips https://switch4good.org/dairy-free-swaps-guide SUPPORT SWITCH4GOOD https://switch4good.org/support-us/ ★☆★ JOIN OUR PRIVATE FACEBOOK GROUP ★☆★  https://www.facebook.com/groups/podcastchat ★☆★ SWITCH4GOOD WEBSITE ★☆★ https://switch4good.org/ ★☆★ ONLINE STORE ★☆★ https://shop.switch4good.org/shop/ ★☆★ FOLLOW US ON INSTAGRAM ★☆★ https://www.instagram.com/Switch4Good/ ★☆★ LIKE US ON FACEBOOK ★☆★ https://www.facebook.com/Switch4Good/ ★☆★ FOLLOW US ON TWITTER ★☆★ https://twitter.com/Switch4GoodOrg ★☆★ AMAZON STORE ★☆★ https://www.amazon.com/shop/switch4good ★☆★ DOWNLOAD THE ABILLION APP ★☆★ https://app.abillion.com/users/switch4good

Send us a textThe body keeps the score, but it also leaves clues—and midlife is when those clues get loud. I share a clear, data-backed path through perimenopause: the first strange symptoms, the shrugged-off labs, and the moment I decided to stop tolerating discomfort and start tracking what mattered. If you've been told “you're fine” while your hair breaks, your mood swings, your jeans won't zip, and your LDL creeps up, this conversation hands you a roadmap.We unpack the real turning points: timing hormone tests to the luteal phase and discovering near-zero progesterone, starting targeted HRT and monitoring results, and replacing performative cardio with short, intentional strength training to protect bone density and rebuild lean mass. I talk through raising protein, prioritizing recovery, and the overlooked variable that changed my labs—reviewing long-term psychiatric medication that can elevate LDL, then tapering safely with medical guidance. Finally, I demystify peptide therapy: what it is, how to vet a provider, why labs matter before and after, and what shifted for me when I paired peptides with smarter training and a cleaner med list.This is a practical, compassionate guide for women who want to feel strong, clear, and in charge during perimenopause. You'll hear the exact steps I took, the questions I asked, and the metrics I watched as my LDL dropped from 140 to 111 and my energy and composition improved. No quick fixes, no shame—just a precise stack and persistent self-advocacy. If you're ready to trade confusion for a plan, press play, share this with a friend who needs it, and then subscribe and leave a review to help more women find this resource. What's the first question you'll ask your doctor this week?To book a FREE discovery call with Dr. Harte, click the link below:https://calendly.com/drharte/free-discovery-call-w-dr-harteSupport the show#thetruthaboutaddiction#sobriety#the12steps#recovery#therapy#mentalhealth#podcasts#emotionalsobriety#soberliving#sobermindset#spirituality#spiritualgrowth#aa#soberlife#mindfulness#wellness#wellnessjourney#personalgrowth#personaldevelopment#sobermovement#recoveroutloud#sobercurious#sobermoms#soberwomen#author#soberauthor#purpose#passion#perspective

The Truth About Cholesterol, LDL, and Plaque Regression with Dave Feldman | Lean Mass Hyper-Responder Research Explained What if everything you've been told about cholesterol and heart disease is incomplete — or even wrong? In this eye-opening episode of The Coach Debbie Potts Show, I sit down with Dave Feldman, engineer turned citizen scientist, founder of Own Your Labs and The Citizen Science Foundation, and the mind behind the Lean Mass Hyper-Responder (LMHR) study and the groundbreaking Keto-CTA trial on plaque progression and regression. We unpack the latest findings from Dave's multi-platform coronary imaging study — comparing HeartFlow, QAngio, Cleerly, and expert readouts — to explore how some individuals with very high LDL cholesterol and low inflammation show no increase in plaque and, in some cases, true regression. You'll learn:

“When your client says their body changed overnight, she's not exaggerating.” - Dr. Jessica DrummondSo many women arrive in perimenopause or menopause feeling blindsided by the changes in their bodies. They're exercising, eating well, and they might even be using hormone replacement therapy (HRT), but no matter what they do, they're noticing weight gain around the middle, higher cholesterol, or shifts in their blood sugar. It can be discouraging for both the client and for us as practitioners when all the usual tools stop working. But these changes are not about willpower or doubling down. They're about physiology.During the menopause transition, the body goes through a true metabolic shift. Even women who seem to be perfectly healthy can experience significant changes in body composition, energy, and cardiovascular health. Research shows that each year of the menopause transition brings about a 1.7% increase in visceral fat and that LDL cholesterol can rise by up to 12%. Understanding how and why these physiological changes happen is the key to better supporting our midlife clients with compassion, structure, and confidence.Today, I'm breaking down everything about metabolism in midlife. I'm sharing the key findings from the SWAN study, how hormones, insulin resistance, and SHBG work together to influence weight, blood sugar, and energy, practical strategies for assessing and supporting clients through these changes, integrating the Confidence in Complexity framework for long-term results, and more.Enjoy the episode, and let's innovate and integrate together!---Learn more or watch the video version of this conversation at https://integrativewomenshealthinstitute.com/the-metabolic-shift-helping-women-clients-with-weight-gain-blood-sugar-and-cholesterol-in-midlife/.Connect with me and access our entire platform at IntegrativeWomensHealthInstitute.com (https://integrativewomenshealthinstitute.com/). Find and follow us @integrativewomenshealth on YouTube (https://www.youtube.com/@integrativewomenshealth) and Instagram (https://www.instagram.com/integrativewomenshealth/).

Most people are told: your cholesterol is high, here's a statin, especially if it's high LDL. End of discussion.But what if that prescription isn't always necessary? What if there are tests and questions that could completely change the outcome?In this episode, we dive into the truth about statins and diabetes, the benefits, the risks, and the controversies you rarely hear about. You'll also hear Mary's story, how she was nearly put on statins but, with the right evidence and one extra test, discovered she didn't need them at all.For show notes and resources, please visit: https://Type2DiabetesTalk.comTo share your questions and suggestions, leave us a voice message or email at: https://Type2DiabetesTalk.com/messageExplore our proven programs and services, visit: https://Type2DiabetesTalk.com/programsSubscribe to our free weekly newsletter for podcast updates, valuable nutrition tips and more: https://Type2DiabetesTalk.com/subscribe

The (Almost) Effortless Daily Habit That Can Lower Cholesterol, Boost Brain Health Drinking tea daily can lower LDL cholesterol, support heart health, and may help reduce brain lesions linked to dementia. Tea also filters heavy metals from water, offers L-theanine and is more moderate in caffeine than coffee. Listen for details. Written by Dana Hudepohl at forksoverknives #vegan #plantbased #plantbasedbriefing #tea #greentea #dementia #heavymetals #cholesterol #brainhealth ====================== Original post:  https://www.forksoverknives.com/wellness/effortless-habit-lower-cholesterol-boost-brain-health-with-tea/    Forks Over Knives Documentary: https://www.forksoverknives.com/the-film/  =========================== Forks Over Knives was founded following the release of the world-famous documentary Forks Over Knives in 2011, showing people how to regain control of their health and their lives with a plant-based diet. Since then Forks Over Knives released bestselling books, launched a mobile recipe app and maintains a website filled with the latest research, success stories, recipes, and tools to help people at every phase of their plant-based journeys. They also have a cooking course, a meal planner, a line of food products, and a magazine. Please visit www.ForksOverKnives.com for a wealth of resources.  FOLLOW THE SHOW ON: YouTube: https://www.youtube.com/@plantbasedbriefing     Spotify: https://open.spotify.com/show/2GONW0q2EDJMzqhuwuxdCF?si=2a20c247461d4ad7 Apple Podcasts: https://podcasts.apple.com/us/podcast/plant-based-briefing/id1562925866 Your podcast app of choice: https://pod.link/1562925866  Facebook: https://www.facebook.com/PlantBasedBriefing     LinkedIn: https://www.linkedin.com/company/plant-based-briefing/   Instagram: https://www.instagram.com/plantbasedbriefing/  

In this follow-up to his deep dive on protein, Darin exposes the other side of the protein story: where your food comes from, what's really in it, and how the system itself affects your health, the planet, and the animals. From factory farm contamination to antibiotic resistance, industry lobbying, and why plants still win on every level — Darin breaks down the research, ethics, and environmental data so you can make conscious choices that fuel a truly SuperLife. What You'll Learn [00:00] Welcome + sponsor message: plastic waste, conscious products, and Bite Toothpaste [02:47] Introduction — the real protein conversation continues [03:00] The source of your food matters more than macros [03:10] Contamination, ethics, and the reality of factory farming [03:30] Stewardship vs. dominion — a call for responsibility [04:01] EPA data: confined animal operations and environmental chaos [05:00] Foodborne illness: salmonella, E. coli, and what contamination really means [05:57] Antibiotics, resistance, and hormones in animal agriculture [06:42] Persistent pollutants (PFOAs) showing up in food and milk [07:10] How animal feed (soy and corn) drives ecological damage [07:57] USDA marketing boards + industry lobbying against plant alternatives [08:38] Darin's 17 years vegan — data and lived experience [09:00] The numbers: amino acids, LDL, fat swaps, and longevity [09:47] Common plant-based protein myths answered [12:59] Patreon message — upgrade your operating system and join the tribe [14:03] The cancer connection: processed and red meat research [14:47] Iron, B12, and what vegans actually need to know [15:37] Soy, testosterone, and thyroid myths debunked [16:08] Protein quality: why mixing plant foods covers all bases [16:31] Feeling better on moderate meat? Understanding the trade-offs [17:18] Substitution data: even small swaps improve health outcomes [17:57] Processed vs. ultra-processed: why Beyond Meat isn't the enemy [18:09] Environmental impact: why beef's footprint dwarfs plant protein [19:05] Food miles myth — what you eat matters more than distance [19:29] Cost and accessibility: the cheapest protein sources are plants [20:08] Contamination and antibiotic resistance rising annually [21:03] Anti-nutrients and the myth of plant dangers [21:47] Real-world evidence: fiber, polyphenols, and legume-based longevity [22:00] Final recap — all essential amino acids come from plants [22:17] Strongest evidence: plant protein wins ethically, environmentally, and scientifically Thank You to Our Sponsors: SuperLife Patreon: Go towww.patreon.com/DarinOlien and sign up to start changing your life today Bite Toothpaste: Go to trybite.com/DARIN20 or use code DARIN20 for 20% off your first order. Connect with Darin Olien: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences Platform & Products: superlife.com Key Takeaway "All plants contain all essential amino acids. The more you swap red meat for plants, the longer, stronger, and cleaner your life becomes."

Heart disease is still our number one killer, even though 50 million Americans have been prescribed a cholesterol-lowering statin. Cardiologists pay a lot of attention to cholesterol in all its variety: total cholesterol, LDL, HDL, VLDL. Even blood fats like triglycerides and lipoprotein a [Lp(a)] are getting some attention. What else do you need to […]

I used to think of fiber as just “good for digestion,” but it turns out this single nutrient can lower cholesterol as powerfully as a statin—and do so much more for your brain, gut, and longevity. In this minisode of The Neuro Experience, I sit down with Dr. Rupy Aujla — NHS doctor, author, and founder of The Doctor's Kitchen — to break down the science behind fiber and why it's one of the most underrated tools for preventing heart disease and inflammation. This episode features highlights from our full conversation, which premiered August 5th, 2025. Watch the full episode here → https://www.youtube.com/watch?v=Jay-Sg2sg6s Connect with Dr. Rupy Aujla: Website: The Doctor's Kitchen Instagram: @doctors_kitchen Books: The Doctor's Kitchen & Eat to Beat Illness *** Topics discussed: 00:18 – The TikTok “fiber maxxing” trend explained 00:42 – How to transition from low-fiber to high-fiber safely 01:02 – How fiber binds cholesterol and removes it from the body 01:26 – Feeding your gut microbes: the real reason fiber matters 02:10 – What short-chain fatty acids do for inflammation and longevity 03:00 – How fiber increases LDL receptor activity in the liver 03:42 – How 60 days of high-fiber eating lowers ApoB and LDL 04:03 – The “Portfolio Diet” that rivals statins 05:08 – The best fiber-rich foods: oats, barley, soy, nuts, seeds 06:14 – What to know about oats, glyphosate, and processing 07:16 – The perfect high-fiber breakfast recipe 07:53 – How food can match statin effects (and go beyond) 09:10 – The one daily change to reduce heart attack and stroke risk 09:26 – Dr. Rupy's B.B.G.S. formula for everyday health 10:13 – How fiber diversity transforms cholesterol and gut health *** I'm Louisa Nicola — clinical neurophysiologist — Alzheimer's prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer's risk — and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices

High cholesterol no matter what you eat? You could have familial hypercholesterolemia - a genetic condition that causes very high LDL (“bad”) cholesterol levels even with a healthy lifestyle. In this episode, dietitian Teresa Wagner explains what familial hypercholesterolemia (or FH) is, why it happens, and what you can do to protect your heart.

I recently had an ApoB test and am surprised that it isn't lower than it is.  Can you explain?I have an ascending thoracic aortic aneurysm.  How can I keep it from enlarging?Why are you against whole-body scans? Aren't they helpful?Can I take magnesium L-threonate while also taking magnesium glycinate?

Will Truheight vitamins really make your kids grow?Where can I learn more about complementary medicine and nutrition?The balls of my feet are sore along with my toes. Is this a vitamin deficiency?

The Real Truth About Cholesterol, Heart Disease & Cardiovascular Health SUMMARY What if your cholesterol isn't trying to kill you—it's trying to protect you? In this solo deep-dive, Coach Debbie Potts breaks down the outdated cholesterol myths and reveals the root-cause truth behind cardiovascular disease. Drawing from the work of Dave Feldman, Dr. Ben Bikman, Dr. Paul Mason, Ivor Cummins, and Dr. William Davis, Debbie explains why heart disease is an inflammatory, metabolic, and endothelial problem—not a cholesterol problem. Learn which markers truly predict risk, how to interpret your labs beyond LDL, the role of genetics and epigenetics, and what it really takes to reverse plaque and rebuild a resilient metabolism. If you're ready to move beyond fear and finally understand your cardiovascular health through the lens of functional, ancestral, and root-cause medicine, this episode is your roadmap. KEY TAKEAWAYS LDL isn't "bad"—oxidized, inflamed LDL in a damaged arterial wall is. Heart disease = terrain dysfunction: insulin resistance, oxidative stress, mitochondrial damage, and loss of nitric oxide. ApoB + inflammation predict risk far better than total cholesterol. Context matters: High LDL in a low-inflammation, insulin-sensitive body ≠ the same risk as in a high-inflammation body. Saturated fat isn't the enemy; oxidized seed oils and sugar are. You can't out-supplement poor habits. Sleep, stress regulation, circadian alignment, and daily movement build vascular resilience. Plaque can stabilize or regress when you heal the root causes. The WHOLESTIC Method™ integrates nutrition, movement, sleep, stress, digestion, hydration, and happiness to rebuild your health from the inside out. TESTS & TOOLS MENTIONED - talk to your provider! ApoB (< 80 mg/dL optimal) LDL-P (< 1,000 nmol/L) Triglyceride : HDL ratio (< 1) hs-CRP (< 0.5 mg/L) Lp(a) (< 30 mg/dL) Fasting Insulin / HOMA-IR (< 5 µIU/mL / < 1.0) Coronary Artery Calcium (CAC) Score (0 = clean) CCTA / Cleerly AI Analysis for plaque composition Carotid IMT, Omega-3 Index, Homocysteine, Vitamin D + K2

Today, we're tackling a question that comes up often in peptide, weight loss, and nutrition clinics: why does one person see great results with semaglutide, while another responds better to tirzepatide—or even retatrutide? If you want to support what we do, head over to our Partners Page. You'll find some amazing brands we trust—and by checking them out, you're helping us keep the podcast going. https://pepties.com/partners/ All three peptides target the incretin system, but they act in slightly different ways—and those differences can dramatically affect outcomes. Let's start with the basics. Semaglutide is a GLP-1 (glucagon-like peptide-1) receptor agonist. It mimics the gut hormone GLP-1, which increases insulin when blood sugar is high (to help lower blood sugar), suppresses glucagon (which also decreases blood sugar), and slows gastric emptying. It also enhances satiety—so you feel full longer and eat less. Tirzepatide is a dual agonist, acting on both GLP-1 and GIP receptors. GIP—glucose-dependent insulinotropic polypeptide—also helps with insulin secretion to lower blood sugar, increases fat metabolism, and may reduce some of the GI side effects seen with GLP-1 alone. Retatrutide, the newest in the lineup, is a triple agonist that targets GLP-1, GIP, and glucagon receptors. Retatrutide lightly activates the glucagon receptor while strongly activating GLP-1 and GIP receptors, which help regulate blood sugar and boost insulin secretion. This keeps blood sugar stable—or even improves it. Beyond blood sugar, glucagon also ramps up metabolism and calorie burning. By gently engaging glucagon receptors, retatrutide can increase energy expenditure and support fat loss without triggering large blood sugar spikes. So how do you decide which one might work best? Let's walk through common clinical situations. Patients with Hypothyroidism Let's talk about hypothyroidism. People with hypothyroidism often have slower metabolism, making weight loss more difficult even with a balanced diet. Low thyroid hormone levels slow calorie burning and energy use, so weight gain can occur more easily. For these patients, semaglutide is a reliable starting point—it helps regulate appetite and caloric intake. If progress plateaus, tirzepatide or retatrutide may provide an edge by boosting energy expenditure and fat oxidation, essentially "jump-starting" a slower metabolism. Patients with PCOS (Polycystic Ovary Syndrome) What about patients with PCOS (polycystic ovary syndrome)? Insulin resistance is common in PCOS, often leading to higher androgen levels (e.g., testosterone) and symptoms like irregular periods, acne, and excess hair growth. Hormonal changes also affect appetite-regulating hormones, increasing hunger and cravings. Both GLP-1 and dual agonists have proven effective in managing metabolic and reproductive aspects of PCOS. Typically, we start with semaglutide to improve weight, insulin sensitivity, androgen levels, and menstrual regularity. After a few months, if weight loss plateaus or cravings remain high, we may switch to tirzepatide. The added GIP activity enhances fat metabolism, insulin control, and may further support hormone regulation and ovulation. The key is starting with what's well-studied and tolerated, then stepping up if additional metabolic or reproductive support is needed. Type 2 Diabetes (T2DM) The next medical condition I'd like to talk about is type 2 diabetes (T2DM). Weight gain in T2DM often stems from insulin resistance. Cells don't respond effectively to insulin, prompting the pancreas to relelase more. High insulin levels encourage fat storage, particularly around the abdomen, while elevated blood sugar can increase hunger and cravings. Some diabetes medications, like insulin or sulfonylureas (e.g., glipizide or glyburide), can also contribute to weight gain. All three drugs lower blood sugar and promote weight loss, but tirzepatide currently shows the strongest combined A1c reduction (average blood sugar over the past 2 to 3 months) and weight loss. GIP and GLP-1 work together to enhance insulin response more effectively than GLP-1 alone. Retatrutide is in phase 3 trials, with potential FDA approval as early as 2027. Its glucagon receptor activity may offer additional glucose regulation and energy expenditure benefits. Patients with >15% Weight Loss Goals Okay, let's talk about weight loss goals and how this ties into the decision process for choosing a weight loss medication. For those patients looking to lose more than 15% of their total body weight, tirzepatide or retatrutide are likely to deliver greater results. Clinical data show semaglutide can achieve up to 15% total weight loss while tirzepatide can achieve up to 22% and retatrutide up to 24%. That said, semaglutide remains a highly effective option for weight loss. However, if progress begins to plateau, transitioning to a dual or triple agonist may help restart weight loss and push past that plateau. Pre- and Postmenopausal Women What about peri- and postmenopausal patients? Hormonal shifts during perimenopause and menopause slow metabolism and can increase cravings. Declining estrogen promotes abdominal fat storage and affects appetite-regulating hormones. Semaglutide helps with appetite control and gradual fat loss, while tirzepatide's GIP activation can further support fat metabolism when estrogen levels drop. Patients with Heart Disease or High Cholesterol The last group of patients I'd like to discuss is patients with heart disease (e.g., heart failure, stroke, heart attack, or even atherosclerosis) or people with high cholesterol. Semaglutide has the strongest cardiovascular outcomes data, reducing major adverse cardiac events by 20% and improving LDL cholesterol (bad cholesterol) and blood pressure. Tirzepatide shows promise for heart and lipid benefits, but those trials are still ongoing. For patients with prior heart attack, stroke, or severe coronary artery disease, semaglutide remains the safest evidence-backed starting point—unless intolerable side effects or weight loss resistance occur. Tolerability Now I want to switch gears a bit and talk about side effects and tolerablity of these peptides. Some patients experience stomach-related side effects like nausea, bloating, or acid reflux on semaglutide. Generally, tirzepatide tends to cause fewer GI side effects, likely due to GIP balancing GLP-1 activity in the gut. So patients struggling with nausea or other stomach-related side effects may find tirzepatide more tolerable. Just something to keep in mind. Individualizing Therapy Lastly, I want to highlight the importance of individualizing weight loss peptide treatments. There's no one-size-fits-all approach when it comes to these therapies. Clinicians should carefully consider a patient's goals, medical history, current medications, and tolerance before choosing the most appropriate option. Setting realistic expectations from the start is essential. It's important to remember that everyone's body responds differently because of factors like hormones, genetics, metabolism, gut microbiome balance, and lifestyle habits. These differences influence how effectively a peptide therapy works and how well it's tolerated. That's why ongoing monitoring and follow-up are such an important part of the process. Providers track progress, adjust dosing when needed, and switch medications if weight loss plateaus or side effects occur. The goal isn't just to lose weight quickly—it's to create a safe, sustainable plan that supports long-term metabolic health and helps patients feel their best. Thanks for listening to The Peptide Podcast.  If you want to support what we do, head over to our Partners Page. You'll find some amazing brands we trust—and by checking them out, you're helping us keep the podcast going. Until next time, be well, and have a happy, healthy week.

High cholesterol no matter what you eat? You could have familial hypercholesterolemia - a genetic condition that causes very high LDL (“bad”) cholesterol levels even with a healthy lifestyle. In this episode, dietitian Teresa Wagner explains what familial hypercholesterolemia (or FH) is, why it happens, and what you can do to protect your heart.

Send us a textJosh Wageman is a returning guest on our show! Be sure to check out his first appearance on episode on 869 of BBR!Josh Wageman is a Clinical Lipid Specialist with multiple doctoral degrees who formerly practiced in Endocrinology. His PhD work focused on cholesterol disturbances in Alzheimer's Disease and, although he also has a Doctorate in Physical Therapy, he is best known for his role in teaching lipid physiology.He serves as an adjunct professor at several medical programs and his goal is to help you, whoever you are, NOT have heart attacks, strokes, and dementia by explaining complicated biochemical concepts in a relatable way!Employing a smorgasbord of metaphors, pictures, and catchphrases, his latest book The Home Security System and the Lipid Neighborhood serves as a valuable reference for clinicians and non-clinicians alike, bringing refreshing relatability to complex biochemical topics. Through a lipid-lens, you'll learn, laugh, and love your way through its pages…and in the end, you'll undoubtedly add “life to your years!”Josh is active in Youth Ministries at Heritage Bible Church in Boise, Idaho, and resides there with his family. He also enjoys Crossfit, basketball, Ultimate Frisbee, and all sports that don't involve skates.Find Dr. Wageman at-Amazon- The Home Security System and the Lipid Neighborhood IG- @wagemanjoshLK- @Josh WagemanFind Boundless Body at- myboundlessbody.com Book a session with us here!

In this episode, we are joined by Dr. Pradyumna J. Oak. Dr. Oak is a Senior Neurologist and Director of Neurology at Nanavati Super Speciality Hospital, Mumbai. His extensive experience in stroke management and neurocritical care makes him a perfect expert to speak on brain stroke. Vikas & Dr. Oak discussed causes, diagnosis, risk factors, important tests, and primary and secondary prevention.Here are some key takeaways: Blockages in blood vessels supplying blood to the brain may lead to a brain stroke. It is different from a heart attack or cardiac arrest.Diabetes, hypertension, Obesity, smoking, and use of tobacco are the major risk factors that contribute to a brain stroke.Statins may help stabilize the plaque and reduce LDL cholesterol levels.Brain stroke can happen due to occlusion (blockage) in arteries or hemorrhage(rupture) of blood vessels. A person experiencing a Transient Ischemic Attack might have difficulty speaking. Unfortunately, in the symptoms of a brain stroke, there is no pain. Running and other endurance activities may help condition your heart and even keep your baseline heart rate in check.A well planned workout program is helpful in mitigation of similar issues including a condition such as brain stroke.About Vikas Singh:Vikas Singh, an MBA from Chicago Booth, worked at Goldman Sachs, Morgan Stanley, APGlobale, and Reliance before coming up with the idea of democratizing fitness knowledge and helping beginners get on a fitness journey. Vikas is an avid long-distance runner, building fitpage to help people learn, train, and move better.For more information on Vikas, or to leave any feedback and requests, you can reach out to him via the channels below:Instagram: @vikas_singhhLinkedIn: Vikas SinghTwitter: @vikashsingh101Subscribe To Our Newsletter For Weekly Nuggets of Knowledge!

In this Facebook Live episode, Shana shares how she naturally lowered her total cholesterol by 58 points and LDL by 41 points in just 11 weeks—without statins—by addressing insulin resistance and easily adding 7 different fibers with the Feel Great System. You'll learn what causes "high" cholesterol beyond diet, how insulin and inflammation play a bigger role than fat intake, and how strategic nutrients like soluble fibers, phytosterols, and chlorogenic acid improve both lipid and glucose metabolism. What You'll Learn The real root of high cholesterol: insulin resistance and poor metabolic signaling. Why statins don't fix insulin resistance—and what they actually do. How Balance (soluble fiber matrix) supports healthy LDL, satiety, and blood sugar control. Guar gum, beta-glucans, gum arabic, citrus pectin → lower LDL, stabilize glucose, support gut microbiota. Phytosterols → reduce LDL and raise HDL. Chromium → enhances insulin sensitivity, reduces sugar cravings. Niacin → supports HDL and energy metabolism How Unimate (yerba mate extract) enhances GLP-1, focus, and fat metabolism. Chlorogenic acid → reduces LDL/triglycerides, improves insulin sensitivity, and supports mitochondrial energy. Theobromine → improves HDL/LDL ratio, boosts mood and alertness without jitters. Mate saponins and polyphenols → lower visceral fat, protect the liver, and calm inflammation How improving GLP-1 naturally helps you feel full longer, lose weight, and stabilize blood sugar. Simple lifestyle rhythms—light, sleep, meal timing—that magnify your results. Key Takeaways Fixing insulin resistance improves both cholesterol and blood sugar markers. The Feel Great System is listed in the Physician's Desk Reference (PDR) and backed by published studies. You can partner with your clinician to explore reducing or avoiding cholesterol meds as metabolic health improves. Supporting GLP-1 naturally with Feel Great can mimic some benefits of popular medications—without side effects. Products Mentioned

Hour 3 for 10/28/25 Dr. Sean O'Mara joined Drew to discuss all things sugar (4:19). Topics included: why sugar is addicting (12:13), diet soda (16:10), sugar's connection to cancer (16:10), sugar's connection to cancer (19:44), good habits (24:01), honey (27:59), RX bars (30:23), fermented foods (34:53), sports nutrition (41:23), alcohol (44:22), LDL cholesterol (47:56). Original Air Date: 10/30/24

We break down the five health numbers that forecast cardiovascular and metabolic risk and turn them into a simple plan you can act on today. Clear targets, practical measurement tips, and small habits help you lower risk and feel better fast.• why blood pressure thresholds matter and how to measure right• LDL, HDL, triglycerides and the power of ratios• diet swaps and exercise that shift lipid panels• fasting glucose versus A1C and what each reveals• quick wins to improve insulin sensitivity• why waist beats BMI for risk prediction• building muscle for long-term metabolic health• resting heart rate, HRV and recovery heart rate• a step-by-step system to track, trend and act• red flags that mean it's time to see a doctorIf you'd enjoyed today's episode, I'd love for you to share it with your friends and familyAnd if you're feeling generous, consider donating at the link provided in the descriptionFor more resources, tips, and updates, don't forget to visit our website at www.kore-fit.com and follow us on Instagram at KoreFitnessAZJoin our community and let's continue this journey together"Transform Your Life with Kore Fitness"Kore Fitness: Your path to a healthier, stronger you. Personalized training and proven results.Disclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showhttps://www.kore-fit.com

In this episode of Wholistic Living, we're unpacking the truth about HbA1c, insulin resistance, and metabolic health, beyond just what you eat. You'll learn exactly what HbA1c measures, how insulin works on a cellular level to move glucose into your cells for ATP energy, and what happens when that process breaks down. We'll explore how stress, poor sleep, inflammation, toxins, and hormone imbalances all drive insulin resistance, even if your diet looks “clean.” I also share the most effective supplements for improving insulin sensitivity and supporting healthy HbA1c levels, including magnesium, inositol, berberine, fish oil, NAC, glycine, alpha-lipoic acid, and plant sterols and explain how each one helps your cells use glucose efficiently instead of storing it as fat. If you've ever struggled with blood sugar swings, fatigue after meals, high cholesterol, or stubborn weight gain, this episode connects the dots between glucose metabolism, hormones, and holistic healing.Join the 60 Day Gut Reset & Start When You're ready with $200 OFF! https://checkout.teachable.com/secure/1716725/checkout/order_4mzzdrn3?coupon_code=SECRETOFFEREquip Foods Grass-fed beef protein - Code: MARLAWant to work with me? email me to health@holisticspring.com

BUFFALO, NY — October 27, 2025 — A new #research paper was #published in Volume 17, Issue 9 of Aging-US on September 17, 2025, titled “Depletion of the TRF1 telomere-binding protein leads to leaner mice with altered metabolic profiles.” In this study led by first author Jessica Louzame Ruano and corresponding author Maria A. Blasco from the Spanish National Cancer Centre (CNIO), researchers investigated the role of TRF1, a protein known for protecting telomeres, in regulating whole-body metabolism. The results suggest that TRF1 influences metabolic health through mechanisms unrelated to its known function in telomere maintenance. Obesity and metabolic disorders are major health concerns, especially as people age. To explore TRF1's role beyond telomere protection, the research team studied both normal mice and genetically modified mice that lacked TRF1. Mice without TRF1 remained leaner over time, resisted fat accumulation, and showed healthier blood sugar and insulin levels compared to normal mice. Importantly, these benefits occurred without any detectable shortening of telomeres. The leaner body composition in TRF1-deficient mice was not due to reduced food intake or increased physical activity. Instead, the fat loss appeared to result from biological changes in how energy was processed and stored. Male mice without TRF1 gained less weight and had lower LDL cholesterol levels, even on a high-fat diet. Female mice showed milder effects, reflecting known sex-based differences in susceptibility to diet-induced obesity. This highlights the importance of including both sexes in metabolic research. “Major metabolic pathways related with energy production and regulation of metabolism homeostasis were also found downregulated in Trf1-deficient mice.” Gene expression analysis in the liver revealed shifts in several key pathways. Genes related to fat production, energy generation, and muscle growth were downregulated, while genes linked to inflammation and cholesterol synthesis were upregulated. The mice also showed signs of higher energy expenditure and a shift from using fat to protein as an energy source, possibly due to their reduced fat reserves. However, some older mice developed mild liver stress, including fibrosis and DNA damage, suggesting a possible long-term trade-off. Overall, this study expands the understanding of how telomere-related proteins influence more than just cellular aging. By identifying a connection between TRF1 and metabolism, the research opens new possibilities for targeting TRF1 or its pathways to address obesity and related conditions. Still, further studies are needed to clarify how TRF1 affects fat development and whether similar effects occur in humans. DOI - https://doi.org/10.18632/aging.206320 Corresponding author - Maria A. Blasco — mblasco@cnio.es Abstract video - https://www.youtube.com/watch?v=7AG3TBgDZIw Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206320 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, Trf1, metabolism, leaner, fat, telomeres To learn more about the journal, visit https://www.Aging-US.com​​ and connect with us on social media at: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Bluesky - https://bsky.app/profile/aging-us.bsky.social Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

Dr. Ron challenges mainstream cholesterol beliefs, tracing the history of shifting guidelines and the rise of statins as a massive industry. He explains cholesterol's vital roles, the difference between particle types, and how inflammation and oxidized LDL — not cholesterol itself — drive heart disease.The episode offers practical advice: reduce inflammation through real food, sunlight, movement, stress management, and sleep, and encourages listeners to question lab numbers and seek root causes rather than quick pharmaceutical fixes. Please tune in to YouTube on Tuesday at 11 AM named The Real Health Rebellion Radio. Guest Dr. Wong and we will be talking more about cholesterol.

In this episode of Death Clock, Brent speaks with Dr. Nazish Sayed, a Stanford cardiologist and vascular biologist, to cut through the confusion about cholesterol, heart disease, and statins. Dr. Sayed breaks down what LDL, HDL, and ApoB really mean, why high cholesterol is more about your biology than your breakfast, and how inflammation and genetics drive plaque buildup long before symptoms appear. He explains how statins work and why their benefits far outweigh the risks for most people. It's an evidence-based exploration of one of medicine's most misunderstood topics. Hope you enjoy.

Every 80 seconds, a woman dies from heart disease — yet most still think cancer is the bigger threat. In this minisode, I sit down with Dr. Jeremy London, board-certified cardiothoracic surgeon, to unpack why women's cardiovascular risk skyrockets after menopause and how hormones, inflammation, and lifestyle choices all connect. This episode features highlights from our full conversation, which premiered July 24th, 2025. Watch the full episode here → https://www.youtube.com/watch?v=7jbvQRZgb3w Dr. London explains how declining estrogen drives visceral fat, raises cholesterol, and fuels chronic inflammation — creating a “perfect storm” for heart attacks, strokes, and even Alzheimer's. From estrogen and inflammation to cholesterol, exercise, and sleep — this conversation exposes the real science behind heart and brain health. If you've ever wondered how to protect yourself from the #1 killer of women, this episode will change how you think about prevention, hormones, and longevity. *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** I'm Louisa Nicola — clinical neurophysiologist  — Alzheimer's prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer's risk — and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Topics discussed: 00:00 – Why Women's Heart Risk Triples After Menopause 00:55 – Estrogen's Role: Anti-Inflammatory and Protective 01:45 – Weight Gain, Visceral Fat, and Inflammation 02:09 – Cholesterol, LDL, and Rising Risks Post-Menopause 02:38 – The “Perfect Storm” of Metabolic Decline 03:13 – How the Women's Health Initiative Misled Women on Hormones 03:36 – Estrogen, Brain Health, and Alzheimer's Connection 04:45 – The #1 Global Killer: Cardiovascular Disease 05:26 – What “Heart Disease” Really Means 06:00 – Cholesterol Explained: HDL, LDL, and Triglycerides 07:37 – Why ApoB Is a More Accurate Marker 09:18 – Plaque Formation and Early Intervention 10:11 – The Study That Reversed Heart Aging by 20 Years 11:24 – VO₂ Max, Zone-5 Training, and Longevity 12:16 – Resistance Training and “Muscle as the Organ of Longevity” 13:09 – Why Consistency Beats Intensity 13:57 – The Sitting Disease and Daily Movement 14:22 – The Power of Nutrition: “Your Body Is the Soil” 15:02 – Whole Foods, Processed Diets, and Alcohol 16:24 – Can Plaque Be Reversed? The Truth 17:11 – Alzheimer's and Lifestyle: Prevention Starts in Your 30s 18:19 – The Final Pillar: Sleep and Recovery 19:28 – Why Sleep Fuels Brain and Heart Health 20:12 – Which Health Pillar Matters Most for You Learn more about your ad choices. Visit megaphone.fm/adchoices

With a calcium score of zero, is there any fat in your diet?  Are there any recommended supplements for IBS?What is the safest and most appropriate dose of vitamin D3 for most seniors?

INFINITY Study on the timing of thyroid medication ingestionI have a growth near my eye that is changing in color and becoming crusty. What should I do?I've been suffering from hip pain for the last three years. Any suggestions on what to do?Could toxic exposures like mold cause conditions like low thyroid or autoimmunity?

Send us a textCurious why coconut oil can raise LDL for some people yet still show up in diets that improve metabolic health, cognition, and body composition? We get clear on what coconut oil actually is—a family of saturated fats with a rare abundance of medium-chain triglycerides—and why MCTs create ketones that the brain and mitochondria can use even without fasting. Instead of stopping at cholesterol, we look at the fuller picture: insulin resistance, inflammation, triglycerides, and real-world outcomes that drive risk more than a single lab value.We dig into the differences between MCT oil, extra-virgin coconut oil, and refined coconut oil, and when each makes sense. We compare biomarkers to hard endpoints, explain why some populations with high coconut intake have low cardiovascular disease, and explore how diet context flips the script: in a high-sugar diet, lipids can look worse; in a lower-carb, whole-food pattern, markers of metabolic syndrome often improve even if LDL nudges up. Along the way, we share insights on cooking stability, oxidative stress, and the intriguing idea that latitude and season may influence how fats signal thermogenesis and photoprotection.You'll leave with practical takeaways you can use today: how to choose between MCTs and whole coconut oil, how to integrate them into a low-sugar, nutrient-dense diet, and which labs to track beyond LDL, like ApoB, triglyceride-to-HDL ratio, hs-CRP, and fasting insulin. If you've wondered whether coconut oil is a villain or a misunderstood ally, this conversation offers a grounded, outcome-focused way to decide what fits your body and your climate.Enjoyed the conversation? Follow the show, share it with a friend, and leave a quick review so more people can find it.www.thehealthedgepodcast.com

Rethinking Diabetes: 7 Eye-Opening Truths Every Woman Should Knowhttps://rawfoodmealplanner.com/rethinking-diabetes-7-eye-opening-truths-every-woman-should-know/Boost Your Wellness Journey:The Brain Reboot Plan: 5 Simple Daily Shifts for More Focus, Energy & Peacehttps://rawfoodmealplanner.com/brain-reboot-plan/Revitalize Your Brain: A Lifestyle Approach for Women Over 50https://rawfoodmealplanner.clickfunnels.com/webinar-replay-brain-health-breakthrough-coaching-programRESET: 3 Metabolic Mistakes Women 30+ Make And How to Fix Themhttps://rawfoodmealplanner.com/reset-3-metabolic-mistakes-women-30-make-and-how-to-fix-them/The Lancet published a study here https://www.thelancet.com/journals/lanhl/article/PIIS2666-7568(24)00191-0/fulltext emphasizing that young adults (ages 18–39) are a neglected but crucial window for dementia prevention. Most dementia research focuses on mid-to-late life, yet many modifiable risk factors that affect long-term brain health emerge or peak in young adulthood.Key Modifiable Risk FactorsEducation: Low levels reduce cognitive reserve and increase dementia risk.Hearing loss: One billion young adults globally are at risk due to unsafe listening practices.Traumatic brain injury (TBI): High rates from sports, motor accidents, and intimate partner violence.Hypertension: One in 12 young adults is affected; rates higher among Black Americans and in LMICs.Alcohol use: Peaks in early 20s, linked to long-term brain changes.Obesity & physical inactivity: Both rising rapidly; linked to inflammation and cardiovascular risk.Smoking/vaping: 90% of daily smokers start before 26.Depression & social isolation: Peak in early 20s, linked to later ADRD (Alzheimer's disease and related dementias) risk.Diabetes: 4% prevalence in young adults; prediabetes affects 1 in 4.Environmental factors: Air pollution, vision loss, high LDL cholesterol, and even emerging risks like sleep disruption, stress, spirituality, and microplastics.Join the Conversation:Subscribe and share this episode with anyone on their own path of health and transformation. // HOST Samantha Salmon, NBC-HWC Nationally Board Certified Health & Wellness CoachBrain Health Licensed TrainerIntegrative Nutrition CoachIntuitive Eating CoachThe information provided in this broadcast is for educational purposes only and is not intended as medical advice. These statements have not been evaluated by the Food and Drug Administration or the equivalent in your country. Any products/services mentioned are not intended to diagnose, treat, cure, or prevent disease. RawFoodMealPlanner.com © 2025

A study published in the American Journal of Clinical Nutrition showed that eating two eggs daily lowered LDL cholesterol, while high saturated fat diets raised it Researchers found cholesterol from eggs did not raise LDL, but saturated fat from foods like bacon and sausage did, showing food context makes a major difference Eggs provide cholesterol without overloading the liver, allowing it to clear LDL efficiently and preventing artery buildup that increases heart disease and stroke risk Weekly egg intake reduced heart disease deaths by 29% and all-cause mortality by 17% in older adults, highlighting the importance of moderation for protective benefits Choosing pastured eggs, avoiding vegetable oils, and pairing eggs with nutrient-rich whole foods further boost benefits while minimizing harmful omega-6 linoleic acid (LA) intake

Dr. Harald Messsner beleuchtet in dieser Folge die Nebenwirkungen von Statinen zur Cholesterinsenkung, insbesondere im Hinblick auf Muskelschmerzen und Coenzym Q10-Mangel. Er erklärt, warum nicht das native LDL-Cholesterin, sondern oxidiertes LDL die Gefäße schädigt und betont die Rolle von Entzündungen und einem multimodalen Ansatz bei der Behandlung von Bluthochdruck und Risikofaktoren.

Host Dr. Vera Tarman speaks with Daniel Trevor—entrepreneur-turned “citizen scientist” and author of Unholy Trinity: How Carbs, Sugars, and Oils Make Us Fat, Sick, and Addicted, and How to Escape Their Grip. After a near-fatal heart attack, Daniel dove into medical literature, clinician interviews, and self-tracking. He shares the arguments behind his book, why he believes hyperinsulinemia is a “gateway disease,” how diet patterns may influence cardiometabolic risk and cravings, and the testing he advocates so people can “don't guess—test.” We also discuss controversy in nutrition science, harm-reduction ways to experiment with food choices, and how to navigate mixed messages from experts. About our guest Daniel Trevor has founded high-tech companies, worked in anti-aging projects, and spent 20 years as an actor and musician. His health crisis catalyzed a research journey that informed Unholy Trinity. He now writes and speaks about low-carb/keto to carnivore approaches, lab testing, and lifestyle change. What we cover Daniel's pivot from “Mr. Healthy” to heart-attack survivor and researcher Hyperinsulinemia → insulin resistance → cardiometabolic disease (Daniel's “gateway disease” model) Why some people see a rise in LDL on low-carb diets and what advanced lipoprotein testing (e.g., NMR LipoProfile) may reveal “Lean-mass hyper-responder” profile: high LDL with low triglycerides and high HDL—what it means and why it's debated Coronary artery calcium (CAC) scores, soft vs. calcified plaque, and the “CAC paradox” as Daniel understands it Grains, seed oils, and sugar: Daniel's case for their role in appetite, cravings, and disease risk; critique of popular diet guidance Statins, side effects, and absolute risk/benefit as presented by Daniel (and why shared decision-making matters) Practical, harm-reduction steps: food substitutions, lab work, and building a sustainable plan Where Daniel's thinking intersects—and conflicts—with mainstream guidelines, and how listeners can evaluate claims Key takeaways “Don't guess—test.” Daniel urges listeners to use accessible labs and scans (prioritizing a small set if resources are limited) and to pair results with symptoms and function. Protein and structure can reduce chaos. He advocates prioritizing animal protein, minimizing refined carbs/sugars and seed oils, and making like-for-like swaps to lower cravings. Context matters. Individual responses vary (genetics, meds, comorbidities, history with restriction/addiction). Go slow, track, and use support. Hold nuance. Nutrition science evolves; some claims remain contested. Use informed consent and a collaborative care team. The content of our show is educational only. It does not supplement or supersede your healthcare provider's professional relationship and direction. Always seek the advice of your physician or other qualified mental health providers with any questions you may have regarding a medical condition, substance use disorder, or mental health concern.

How do I keep my LDL low enough without compromising my brain and my liver?I read that fish oil can raise LDL cholesterol. Is this true?A questionable case study on pycnogenol

See all the Healthcasts at https://www.biobalancehealth.com/healthcast-blog As the founder and Medical Director of BioBalance® Health, an anti-aging longevity practice for 23 years, I have long sought a blood test that serves as a reliable indicator of aging and disease risk. Identifying those at highest risk allows me to better motivate patients to follow my treatment plan and pursue a longer, healthier life. For people who test negative, I would reassure them they are doing well and encourage them to maintain healthy habits. Over time, I assessed common medical tests that many doctors use to steer patients toward certain treatments that do not reduce pain and may shorten life. I examined the actual risk of death and illness through clinical evaluations and credible, though less publicized, research studies. Here is what I found: Elevated blood lipids are not reliably predictive of vascular plaque. In my experience, both high and low cholesterol patients show similar rates of plaque in Cardiac Calcium Scans. Despite this, primary care physicians often prescribe statins, which may be unnecessary for many. Statins were not initially tested on women, who tend to experience more severe side effects such as cognitive impairment, muscle breakdown, and fatigue, likely because these drugs impact mitochondrial function—the cell's energy source. BMI has long been used to assess whether someone is at a healthy or risky weight, but it is often inaccurate. It overlooks individuals with low muscle and high fat, while labeling muscular people as overweight. As a result, BMI is being replaced by body composition measurements.   Recently, body composition analysis using InBody has become more common than BMI for evaluating patient health, frailty, and muscle mass. Measurements of visceral fat and body composition are considered indicators of current health status. BMI is a straightforward calculation that only uses height and weight, whereas body composition includes assessments of visceral fat and percent body fat. Only one weight- and height-based test directly relates to health status. High muscle mass indicates health, while excess visceral fat signals risk, and normal body fat percentage reflects current—but not future—health. Since body composition can shift over time, it is a useful measure of present health but does not reliably predict longevity and is just one aspect of overall health. Several blood tests can indicate current health, such as fasting blood sugar, HbA1c, IGF-1, and fasting insulin. For assessing future health risks and existing damage, HS-CRP (high-sensitivity C-reactive protein) is crucial, as it measures inflammation—a major factor in unhealthy aging and reduced longevity, especially when levels exceed 3.0. An article in Life Extension (July 2025) refers to persistently high CRP as “inflammaging.”   The Truth About Aging and Inflammation? Temporary spikes in HS-CRP from infections or surgeries usually do not cause lasting issues unless inflammation persists. Chronically high HS-CRP levels (>3) are linked to various age-related diseases, such as obesity, arteriosclerosis, autoimmune disorders, poor dental hygiene, and other conditions that reduce health and lifespan. We now can measure “inflammaging” with HS-CRP blood test.  This test indicates increased risk of heart disease, cancer, stroke, dementia, autoimmune disease, and other degenerative diseases.” A review of studies with more than 400,000 participants revealed that people with a High HS-CRP had 75% increased risk of all-cause mortality compared to people with a low HS-CRP. These studies found that HS-CRP may be a more reliable predictor of heart attack and stroke, than LDL cholesterol! HS-CRP may predict age-related diseases because chronic inflammation leads to issues such as arterial plaque and Alzheimer's. Although white blood cells fight infection, their persistent activity can damage healthy tissue and accelerate age-related conditions. The changes that you can make to decrease inflammation, Inflammaging, include: Fat loss to ideal weight Low inflammatory mediterranean diet Omega 3 oil supplements or in food Daily exercise Probiotics Quercetin supplement Treat joints that are damaged (inflammation is increased with injured joints) At least 3 cups of coffee per day Less than 4 oz of alcohol a day No sugar in the diet ***Replacing hormones to the levels of a young man or women with non-oral hormones, pellet testosterone for men and both testosterone and estradiol for women.   BioBalance® Health assesses new information through medical studies and bases treatments on knowledge of human physiology and the aging processes. No single test can determine if you are aging well, but HS-CRP is a better indicator than cholesterol or BMI. At BioBalance®, we've tested HS-CRP for 20 years and developed treatments to address inflammaging. Citation: Life Extension –July 2025

Your thyroid might be quietly steering more than just your metabolism—it could be influencing your cholesterol levels, heart health, and even stroke risk. In this episode, we break down the hidden ways hypothyroidism and Hashimoto's can affect your cardiovascular system.From subtle shifts in LDL and HDL cholesterol to the real impact of untreated thyroid disease on heart disease and stroke risk, we explore what the numbers might be telling you. And if you've ever wondered whether thyroid medication can actually protect your heart, we've got the answers.Whether you're navigating high cholesterol, concerned about heart health, or just curious about the thyroid-heart connection, this conversation gives you the clarity—and action steps—you need.

What if everything you've been told about diet, cholesterol, and heart disease is wrong? Dr. Philip Ovadia (@ifixhearts) — a board-ceretified cardiac surgeon, founder of Ovadia Health and author of “Stay Off My Operating Table” — uncovers the real root causes of modern health issues. From insulin resistance and the fasting myth to the truth behind cholesterol and statins, Dr. Ovadia breaks down how your diet, metabolism, and mental health are all connected. You'll learn:- Why fasting shouldn't make you cranky — and how to do it rightThe shocking truth about insulin resistance and chronic disease- How the “carnivore diet” may actually protect your heart - Why 75% of heart attack patients have “normal” cholesterol levels- What doctors get wrong about LDL and statinsFollow along on social media: Twitter: https://x.com/bob_iaccino Twitter: https://x.com/jimiuorio LinkedIn: https://www.linkedin.com/in/bob-iaccino/ LinkedIn: https://www.linkedin.com/in/james-iuorio/ Newsletter: http://theunfilteredinvestor.com/

Dr. Jeff Graham sits down with Dr. Damon Forbes to explore the emerging concept of “lean mass hyper-responders”— fit, low-carb individuals who present with unusually high LDL levels. They unpack the physiology behind this pattern, discuss how it differs from familial hypercholesterolemia, and review new data on cardiovascular risk. The conversation offers a nuanced look at how metabolism, diet, and lipid transport intersect in precision medicine.

What happens when a dietitian and a PA sit down to talk about heart disease—from both sides of the exam room?In this episode, Colleen brings together two heart health experts: Michelle Routhenstein, MS, RD, CDCES, a cardiovascular dietitian known for her evidence-based prevention strategies, and Josh Wageman, PA-C, PhD, a clinical lipid specialist who's spent his career studying cholesterol disturbances and Alzheimer's.Together, they tackle one of medicine's most common (and confusing) topics—heart health. You'll hear how each expert thinks, what they prioritize, and how they talk with patients who are juggling elevated LDL, inflammation, insulin resistance, or menopause-related changes. By the end, you'll see how bridging nutrition and medicine leads to smarter, more patient-centered care—because this is how the healthcare team should work anyway. Resources:Episode 38 | Love Your Heart with MichelleEpisode 111 | HDL Good, LDL Bad with JoshEpisode 117 | The Best Diet to Lower Cholesterol with JoshConnect with MichelleBuy Josh's BookAny Questions? Send Me a MessageSupport the showConnect with Colleen:InstagramLinkedInSign up for my FREE Newsletter - Nutrition hot-topics delivered to your inbox each week. Disclaimer: This podcast is a collection of ideas, strategies, and opinions of the author(s). Its goal is to provide useful information on each of the topics shared within. It is not intended to provide medical, health, or professional consultation or to diagnosis-specific weight or feeding challenges. The author(s) advises the reader to always consult with appropriate health, medical, and professional consultants for support for individual children and family situations. The author(s) do not take responsibility for the personal or other risks, loss, or liability incurred as a direct or indirect consequence of the application or use of information provided. All opinions stated in this podcast are my own and do not reflect the opinions of my employer.

A Fortune 250 company in Des Moines, Iowa transformed employee health through a whole-food, plant-based lifestyle.    Discover how Gretchen Barris teamed up with PCRM and Dr. Jim Loomis to launch a 16-week wellness program at Principal Financial that helped 240 participants dramatically lower cholesterol, reverse prediabetes, lose weight, and boost energy — all for just $108 per person.   Chuck Carroll sits down with Jean McGinnis and participants like Malcolm & Suzanne Showalter who conquered migraines, reversed heart disease risk, and experienced newfound vitality. Learn how this evidence-based approach from the Barnard Medical Center and PCRM is revolutionizing corporate wellness — even in the heart of the Midwest!   What You'll Learn in This Episode - How a Fortune 250 company implemented a plant-based program on a small budget - The average 23% LDL reduction and 18% A1C improvement among participants - Why employees reported better sleep, focus, and mental health - The difference between “health care” and “sick care,” explained by Dr. Loomis - How to bring programs like this to your own workplace  

Can strength training, sprinting, and nutrition truly transform women's hormones, metabolism, and longevity? In this episode, Dr. Stephanie Estima — chiropractor, women's health expert, and founder of The Estima Method — breaks down the science of female physiology, muscle, and midlife health. We cover why walking isn't enough, how hormones shape muscle and bone, and why protein and strength training are essential “medicine” for women over 35. Expect myth-busting, practical tools, and empowering insights to help you train and live in sync with your biology. About Dr. Stephanie Estima: Dr. Estima began her career in chiropractic care, where she developed a deep interest in neuroscience, biomechanics, and the body's connection between movement and the brain. After noticing how differently men and women respond to the same health strategies, she became passionate about helping women navigate hormones, metabolism, and midlife health. Where to find Dr. Estima: Instagram: @dr.stephanie.estima Website: https://drstephanieestima.com *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Function Health: Visit https://functionhealth.com/louisa or use gift code NEURO100 at sign-up to own your health. Ketone IQ: Go to https://www.ketone.com/NEURO for 30% OFF your subscription order PUORI: Go to https://puori.com/NEURO and use the code NEURO at checkout for 20% off. AquaTru: Go to https://AquaTru.com now for 20% off (your purifier) using promo code NEURO. AquaTru even comes with a 30-day best-tasting water guarantee. Caraway: Visit https://Carawayhome.com/neuro and take an additional 10% off your next purchase. Jones Road Beauty:  Head to https://Jonesroadbeauty.com and use code NEURO at checkout. *** I'm Louisa Nicola — clinical neuroscientist — Alzheimer's prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer's risk — and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Topics discussed: 00:00 – Intro 03:14 – Reassessing Hormone Therapy in 2025 04:24 – The Rise of HRT & Social Media Awareness 05:37 – Balancing the Conversation: HRT Pros & Cons 06:42 – Lifestyle Levers That Matter More 08:05 – Why Walking Isn't Enough Exercise 10:59 – Muscle Quality & Metabolism Explained 12:29 – Type 1 vs. Type 2 Muscle Fibers 16:25 – Glucose, Muscle, and Longevity18:07 – Bone Health & Estrogen 20:33 – The Power of Impact Training 22:28 – How to Build a “Prescription for Health” 24:06 – The Zone 2 Misconception 26:29 – Progressive Overload & The “Weighted Vest” Myth 27:45 – Sample Lower-Body Workout Blueprint 34:03 – Learning Proper Squat Mechanics 35:28 – The Power of Deadlifts & Hip Hinge Movements 36:46 – Glute Bridges & Unilateral Training 38:35 – Nutrition & Midlife Metabolism 39:47 – How Hormones Change Body Composition 42:06 – Sleep, Insulin, and the Estrogen Cascade 43:59 – Strength Training as Hormone Therapy 45:06 – LDL & Visceral Fat Connection 46:04 – Fasting & Female Metabolism 47:17 – Why Aggressive Fasting Backfires for Women 50:53 – The Dark Side of Fasting Culture 53:22 – Practical Guidelines for Eating Windows 54:03 – Under-Fueling & Protein Deficiency in Women 55:09 – Appetite, GLP-1 Drugs & Metabolic Health Learn more about your ad choices. Visit megaphone.fm/adchoices

This week, Dr. Joel Kahn explores three advanced methods for cleansing the blood. He begins with apheresis, a medical technique that removes LDL cholesterol and Lipoprotein(a), and discusses new developments in access to this life-saving therapy. Dr. Kahn also breaks down two emerging treatments gaining popularity—EBOO (Extracorporeal Blood Oxygenation and Ozonation) and TPE (Therapeutic Plasma Exchange)—and how they may play a role in improving cardiovascular health. In the second half, Dr. Kahn turns to the topic of cholesterol-lowering therapies like statins, emphasizing how long-term use and individualized risk assessment matter more than online debates suggest. He highlights tools such as the Mayo Clinic Statin Decision Aid, PREVENT calculator, and Astro-CHARM calculator to help patients and practitioners make informed decisions.  Thanks to the Fresh Pressed Olive Oil Club for sponsoring this episode. Visit getfreshdrkahn.com for a special offer.

A meta-analysis of low-carb diets for diabetes remission found little to no effect at 12 months, clinically important harms to quality of life, and the deal-killer––an increase in LDL cholesterol.

Heart disease is still the number one killer in the U.S.—but are we even looking at the right markers to prevent it? In this eye-opening episode, Shana sits down with Dr. Urban Kiernan, founder and CEO of iMetabolic Biopharma Corporation, to break down what your lipid panel actually means, why total cholesterol and LDL often distract from the real risks, and how insulin resistance plays a central role in heart disease—especially during menopause. Dr. Kiernan shares how his biotech company is leveraging AI, protein therapy, and root-cause science to transform how we prevent and treat metabolic disease—and why most conventional approaches miss the mark entirely. If you've ever been confused by your labs, put on statins without a full explanation, or wondered why we're still seeing record rates of heart attacks and strokes, this conversation will bring clarity and direction.

Can you really lower cholesterol with food? Dr. Michael Greger joins Chuck Carroll on The Exam Room Podcast to reveal the simple, science-backed foods and spices that can drive LDL cholesterol down—without drugs or side effects. Discover how everyday choices can protect your heart and add years to your life.   What You'll Learn in This Episode:   - Why the Standard American Diet is now the #1 cause of death in the U.S. - The truth about statins: small benefit, real risks. - How plant-based eating can reverse heart disease. - Foods that raise cholesterol: meat, dairy, eggs, coconut & palm oils. - The top foods and spices proven to lower LDL include black soybeans, apples, and garlic powder. - Why olive oil raises cholesterol on a vegan diet. - Green tea and mushrooms: health boosters, but not major LDL-reducers. - Practical tips: even one small daily change makes a big difference.  

Send us a textThe surprising link between oral bacteria and heart disease.Episode Summary: Dr. Pekka Karhunen explains the connection between oral bacteria, cholesterol, and cardiovascular disease, discussing how oxidized LDL cholesterol triggers inflammation in arteries, how bacteria from the mouth can infiltrate arterial plaques to form biofilms, and the implications for heart disease prevention through lifestyle changes like better oral hygiene.About the guest: Pekka Karhunen, MD, PhD is a medical doctor and forensic pathologist with decades of experience, specializing in cardiovascular diseases. He has created a unique biobank of coronary arteries from over 10,000 autopsies conducted in Finland. His research focuses on the role of bacteria in atherosclerosis, particularly through studying coronary artery plaques.Discussion Points:Cholesterol is essential for life, but oxidized low-density lipoprotein (LDL) cholesterol is seen as a foreign substance by the immune system, leading to chronic inflammation in coronary arteries.Macrophages ingest oxidized LDL, turning into dysfunctional foam cells that contribute to plaque buildup, known as atheromas, in arteries.Plaque rupture, potentially caused by increased pressure from cholesterol accumulation or hemorrhage within the plaque, can trigger heart attacks.Bacteria, especially from the mouth, can enter arterial plaques via bacteremia (e.g., from dental procedures) and form biofilms, evading immune detection.Biofilms in plaques, made of extracellular matrix like polysaccharides, protect bacteria and may contribute to plaque instability or calcification over time.Poor oral hygiene is linked to higher cardiovascular disease risk, as bacteria from dental infections can enter plaques, suggesting dental care as a preventive measure.Karhunen's research found oral bacteria, like Viridans streptococci, in coronary plaques, with unpublished data also detecting gut and skin bacteria, indicating diverse bacterial involvement.Related content:M&M 247: Cholesterol: Immune Benefits, Heart Health, Statins & Research Malpractice | Uffe Ravnskov*Not medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

Harvard MD/PhD Nick Norwitz reversed ulcerative colitis, lowered cholesterol with Oreos, and now exposes the cracks in modern medicine. This episode is a masterclass in metabolic rebellion and curiosity.Join the Kiltz Health Certification Course here: 50% DISCOUNT until 10/8/2025: https://buy.stripe.com/fZuaEYbJaeCp4Df2OY0480xJoin the Kiltz Mighty Tribe - It's free: https://kiltz-mighty-tribe.mn.co/0:00 – Nick's medical legacy and why he chose medicine 4:12 – Ulcerative colitis diagnosis and desperation-driven healing 8:45 – Ketogenic diet leads to full remission 12:30 – Why modern medicine fails chronic disease patients 16:05 – Incentives, pharma, and the business of healthcare 20:40 – Why RCTs don't reflect real-world healing 25:10 – Nutrition education gaps in med school 30:00 – GLP-1s, statins, and lifestyle vs. pharma 35:45 – Nick's grocery cart: what he actually eats 41:20 – Red meat and cancer myths 46:00 – The Oreo experiment: lowering LDL with cookies 50:30 – Empowering patients to lead their own health journey 54:00 – “Stay Curious”: Nick's mantra and tattoo 58:00 – Where to follow Nick Norwitz and final reflections

In this episode of The Neuro Experience, I sit down with Dr. Kellyann Niotis—one of the first fellowship-trained preventive neurologists—to reveal how you can protect your brain long before symptoms of Alzheimer's or dementia appear. With Alzheimer's cases expected to triple by 2050, Dr. Niotis explains the difference between dementia types, the real role of genes like ApoE4, and why lifestyle choices may be more powerful than genetics. If you want actionable tools to lower your risk, strengthen your memory, and understand the future of preventive neurology, this conversation delivers science-backed strategies you can start applying today. About Dr. Kellyann Niotis: Dr. Kellyann Niotis is the first fellowship-trained preventive neurologist focused on reducing risk for Alzheimer's, Parkinson's, and Lewy Body Dementia. She launched the nation's first Alzheimer's Prevention Clinic at Weill Cornell and now leads early-detection and brain health research at the Institute for Neurodegenerative Diseases Florida. Her work appears in leading medical journals and has been featured by CNN. *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode:TimelineHead to⁠ http://timeline.com/neuro⁠ to get started. BeamVisit ⁠http://shopbeam.com/TNE⁠ and use code TNE at checkout. Jones Road BeautyHead to ⁠http://Jonesroadbeauty.com⁠ and use code NEURO at checkout. After you purchase, they will ask you where you heard about them. PLEASE support our show and tell them our show sent you. NOCDHead to ⁠http://learn.nocd.com/NEURO⁠ and book a free 15 minute call to get started. Eko HealthGo to ⁠http:/ekohealth.com/NEURO ⁠ for up to $50 off, plus a free chest piece cover.  *** I'm Louisa Nicola — clinical neuroscientist — Alzheimer's prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer's risk — and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ *** Topics discussed: 00:00 – Introduction 01:25 – Preventative neurology 02:23 – Dementia vs. Alzheimer's & Other Types of Dementia 04:08 – What Is Alzheimer's? 05:26 – Clinical Diagnosis: Imaging & Symptoms 07:07 – How Amyloid Disrupts Neural Communication 09:48 – Genetics vs. Lifestyle: Public Misunderstanding 12:02 – Role of Family History & Genetic Risk 14:04 – The ApoE4 Gene Explained15:07 – ApoE Variants 17:08 – ApoE4 and Lipid Transport in the Brain 18:35 – Immune Response & Infection Susceptibility 20:05 – Hormones: Key Role in Brain Health 21:08 – Genotypes & Risk Multipliers 23:01 – ApoE4 Not Always Deterministic: Population Studies 24:15 – Other Genetic Factors Beyond ApoE 25:13 – Biomarkers: Current Use & Limitations 27:13 – Risks of Self-Testing Biomarkers 28:45 – Why Two-Thirds of Patients Are Women 29:46 – Estrogen, Menopause & Neuroprotection 32:07 – Testosterone & Dementia Risk 35:01 – LDL, ApoB & Brain Health Debate 37:01 – Statins & Dementia: Myths vs. Evidence 39:08 – Fear & Misconceptions Around Cholesterol 41:09 – Lipoprotein(a) & Vascular Dementia Risk 44:39 – Brain Vasculature & Hypertension 49:15 – New Alzheimer's Drugs & Risks 55:32 – Why Rates Keep Rising (Lifestyle & Stress) 58:11 – Early Signs 01:00:23 – Tau Protein, Tangles & Neuronal Damage 01:05:49 – Keto vs. Mediterranean 01:07:14 – Personalization & Preference for Mediterranean Diet Learn more about your ad choices. Visit megaphone.fm/adchoices