Podcasts about tirzepatide

Special edition of the JAMA Editor's Summary featuring the JAMA Network articles published at the 2025 European Society of Cardiology Congress. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, with JAMA Executive Editor Gregory Curfman, MD, JAMA Senior Editor Philip Greenland, MD, and JAMA Cardiology Editor Robert O. Bonow, MD, MS. Related Content: Remote Screening for Asymptomatic Atrial Fibrillation Long-Term Anticoagulation Discontinuation After Catheter Ablation for Atrial Fibrillation Systolic Blood Pressure and Microaxial Flow Pump–Associated Survival in Infarct-Related Cardiogenic Shock Helicobacter pylori Screening After Acute Myocardial Infarction Physiology-Guided Complete Revascularization in Older Patients With Myocardial Infarction Fractional Flow Reserve–Guided Complete vs Culprit-Only Revascularization in Non–ST-Elevation Myocardial Infarction and Multivessel Disease Transcatheter or Surgical Treatment of Patients With Aortic Stenosis at Low to Intermediate Risk Semaglutide and Tirzepatide in Patients With Heart Failure With Preserved Ejection Fraction Bivalent RSV Prefusion F Protein–Based Vaccine for Preventing Cardiovascular Hospitalizations in Older Adults High-Dose vs Standard-Dose Influenza Vaccine and Cardiovascular Outcomes in Older Adults Risk of Myocarditis or Pericarditis With High-Dose vs Standard-Dose Influenza Vaccine Clonal Hematopoiesis and Risk of New-Onset Myocarditis and Pericarditis Participation of Women in Cardiovascular Trials From 2017 to 2023 Prevalence, Determinants, and Time Trends of Cardiovascular Health in the WHO African Region

In this episode, Tina returns from a summer break to discuss her experience with microdosing GLP-1, particularly with the peptide Tirzepatide. She shares insights on GLP-1's misconceptions, its benefits for metabolism, and its impact on women in perimenopause and menopause. Emphasizing the importance of individualized medical advice, she shares details of her journey using peptides for her chronic condition, inflammatory issues, and appetite control. Additionally, she introduces her preferred telehealth provider and upcoming programs to support women considering peptide usage. Here's what you'll learn: - How my ulcerative colitis journey led me to try peptides - The mistakes I made buying and mixing peptides at home - The misconceptions I had about GLP-1s and what I learned instead - Why microdosing a GLP-1 might help with inflammation, blood sugar, and appetite - The surprising benefits for women in perimenopause and menopause - How my eating habits completely changed in just eight weeks - Why caffeine and alcohol suddenly aren't as appealing - My current peptide and supplement stack, and what I plan to keep long term - What's next for me and how you can learn more if you're curious Free Training: Hormone-Driven Fat Loss Method: https://carrotsncake.kit.com/5909f18b13 Peptides for Women course: https://carrotsncake.com/offers/3Q7wttmr?coupon_code=PROTOCOL19 Our trusted telehealth partner: https://elliemd.com/tinahaupert https://carrots-n-cake.mykajabi.com/fit+fueled Connect with Tina Haupert: https://carrotsncake.com/ Facebook: Carrots 'N' Cake https://www.facebook.com/carrotsncake Instagram: carrotsncake https://www.instagram.com/carrotsncake YouTube: Tina Haupert https://www.youtube.com/user/carrotsncake About Tina Haupert: Tina Haupert is the owner of Carrots ‘N' Cake as well as a Certified Nutrition Coach and Functional Diagnostic Nutrition Practitioner (FDN-P). Tina and her team use functional testing and a personalized approach to nutrition to help women find balance within their diets while achieving their body composition goals.

Peptides Vs. Steroids: The Safer Road to Building Muscle & Defeating Fat Amslifestylemedicine.com/ About the Guest(s): Dr. Maureen Gibbons, affectionately known as Dr. Mo, is an emergency medicine and obesity medicine board-certified physician turned lifestyle medicine entrepreneur. She is the founder of AMS Lifestyle Medicine, a practice dedicated to helping patients reclaim food freedom, improve metabolic health, and lead fulfilling lives. Dr. Mo is also an accomplished author, guiding individuals through transformative health journeys with works like her latest book, "Freedom to Shift: Lose the Weight and Gain Your Freedom." Episode Summary: In this enlightening episode of The Chris Voss Show, Dr. Mo graces the podcast to share her riveting journey from being an emergency medicine practitioner to a leading figure in lifestyle medicine. Host Chris Voss humorously opens the session, promising listeners an engaging and educative rollercoaster, with guests that are sure to leave listeners both informed and inspired. Dr. Mo delves deep into her personal struggles with weight and eating habits, revealing how her own experiences motivated her to pivot into the field of lifestyle medicine. Tackling a variety of topics, Dr. Mo elaborates on the physiological and habitual causes of weight struggles, highlighting the innovative solutions her practice offers. From cutting-edge medications like Tirzepatide, better known as Manjaro, to the significant impact of hormones on weight and health, Dr. Mo provides valuable insights into how her practice helps patients break free from their chains of food obsession. Through AMS Lifestyle Medicine, Dr. Mo and her team offer telehealth services, including weight management and TRT programs, empowering people to lead healthier, more balanced lives by providing personalized support and actionable strategies. Key Takeaways: Dr. Mo transitioned from a successful career in emergency medicine to focus on lifestyle medicine, inspired by her personal battles with food and weight. Her practice, AMS Lifestyle Medicine, uses innovative treatments like Tirzepatide and lifestyle coaching to help patients overcome metabolic and weight challenges. Hormonal imbalances are pivotal in weight management, and medications like Tirzepatide can effectively address these issues. Dr. Mo emphasizes the importance of understanding the psychological and habitual triggers of weight issues, offering a holistic approach to treatment. Telehealth services provided by AMS Lifestyle Medicine offer patients nationwide access to personalized care and innovative weight management solutions. Notable Quotes: "I knew that I had credentialed a couple years ago because I had someone in COVID, one of my good friends, replaced her income through telehealth." "Medication's a tool, you know, and that's the big thing in the media. Oh, it's a skinny shot. It's a magic pill. I wish." "For a lot of people, and like I said, semaglutide is a great drug for a lot of people, but for some it's just not." "I'm counting the collagen. Leave me alone." "If you're in there and you're like, yeah, I think you guys are crazy and I don't really like the way you do things. You don't pay."

Metformin for Treatment of Knee Osteoarthritis in Patients With Overweight or ObesityOnce-Weekly Semaglutide in Persons with Obesity and Knee OsteoarthritisSemaglutide or Tirzepatide and Optic Nerve and Visual Pathway Disorders in Type 2 Diabetes This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

In this episode of the RWS Clinician's Corner, Margaret Floyd Barry sits down with Dr. Tyna Moore—renowned naturopathic physician, chiropractor, and international speaker with almost 30 years of experience in holistic and regenerative medicine. Dr. Tyna is known for her bold approach to metabolic health, especially her unique use of GLP-1 agonists like semaglutide, not just for weight loss but as powerful tools for longevity, healing, and resilience. Dr. Tyna pulls back the curtain on the true clinical potential of these peptides, busting myths and exploring the nuance lost in today's clickbait headlines.   In this interview, we discuss:   The science behind GLP-1s and GLP-1 Agonists (including mechanism of action and effects) Microdosing/personalized dosing of GLP-1s, including clinical uses beyond weight loss The concept of “cycling” versus lifelong usage (compared to hormone therapy) Potential side effects and dosing management (including contraindications and safety) Compounded GLP-1s: access, regulations, and practicalities Industry resistance, misinformation, and social dynamics Using GLP-1s during gut healing protocols and the limits of natural alternatives The Clinician's Corner is brought to you by Restorative Wellness Solutions.  Follow us: https://www.instagram.com/restorativewellnesssolutions/    Connect with Dr. Tyna Moore: Website: http://www.drtyna.comInstagram: https://www.instagram.com/drtyna/ YouTube: https://www.youtube.com/@drtyna   Click here for Dr. Tyna's Free 4-part video Series, GLP-1 Uncovered. This video series concludes with an offer for her course, GLP-1s Done Right University. Enter coupon code MARGARET to receive a special discount: https://www.drtyna.com/ozempicuncovered   Or, to go directly to the course, GLP-1s Done Right University, click here and enter the same coupon code (MARGARET) to get started.  Timestamps: 00:00 Regenerative Medicine and Hormone Therapy  05:57 Functional Medicine Truth vs. Propaganda  14:17 Regenerative Therapy Requires Low Inflammation  16:08 Widespread Cardiometabolic Health Crisis  22:16 "Managing Health Challenges with Medication"  30:29 "Low-Dose Approach for Diabetes Management"  36:16 "Empowering Patients Through Education"  38:58 Custom Medication Dosing Benefits  44:43 503B Compounding Pharmacies Shutdown  52:51 Understanding Peptides in Modern Healthcare  57:15 Biliary Concerns in GLP-1 Use  59:14 Liver Health and Supplement Advice  01:06:57 Optimizing Gut Microbiome Strategies  01:10:17 "GLP-1 for Health Improvement" 01:15:29 "Rediscovering Physical Fitness" Speaker bio:    With nearly thirty years immersed in the medical field, Dr. Tyna Moore is an expert in holistic regenerative medicine and resilient metabolic health. She is licensed as a Naturopathic Physician and a Chiropractor, drawing on knowledge from both traditional and alternative fields of science and medicine to provide a comprehensive perspective to individuals striving to enhance their health and wellbeing. Dr. Tyna holds degrees from the National College of Natural Medicine, an esteemed naturopathic medical school, and the University of Western States Chiropractic College. Her work is not just about treating symptoms, it's about understanding and healing root causes to build a robust foundation for long term wellbeing. She is well known for her fierce and open-minded exploration of the peptide, Semaglutide/Ozempic, as a longevity tool for healing. Dr. Tyna champions medical autonomy and individual accountability, and she is on a mission to help as many people as possible experience the freedom and joy that health brings.   As the host of The Dr. Tyna Show Podcast, a top ranking podcast in the health and wellness space, and an international speaker, she is dedicated to empowering others to take control of their wellbeing, heal their metabolic health, and build strength and resilience. Her cornerstone recommendations for every patient and listener: weight lifting and sunshine. Additionally, she extends her expertise to support fellow doctors in cultivating their online practices, helping them transition away from the insurance-centric model to reclaim time, financial stability, and freedom.   Dr. Tyna lives in Oregon with her husband and daughter, and is a proud dog mama. Keywords: GLP-1 agonists, semaglutide, tirzepatide, peptides, regenerative medicine, metabolic health, weight loss strategies, microdosing, hormone replacement therapy, insulin resistance, appetite suppression, personalized dosing, compounding pharmacies, side effects, gut health, SIBO (small intestinal bacterial overgrowth), slow motility, inflammation, functional medicine, neuroregeneration, autoimmune conditions, BPC-157, muscle mass, pharmaceutical dosing, diabetes management, cardiovascular health, leaky gut, obesity, perimenopause, patient empowerment, cycling peptides   Disclaimer: The views expressed in the RWS Clinician's Corner series are those of the individual speakers and interviewees, and do not necessarily reflect the views of Restorative Wellness Solutions, LLC. Restorative Wellness Solutions, LLC does not specifically endorse or approve of any of the information or opinions expressed in the RWS Clinician's Corner series. The information and opinions expressed in the RWS Clinician's Corner series are for educational purposes only and should not be construed as medical advice. If you have any medical concerns, please consult with a qualified healthcare professional. Restorative Wellness Solutions, LLC is not liable for any damages or injuries that may result from the use of the information or opinions expressed in the RWS Clinician's Corner series. By viewing or listening to this information, you agree to hold Restorative Wellness Solutions, LLC harmless from any and all claims, demands, and causes of action arising out of or in connection with your participation. Thank you for your understanding.  

From diabetes care to weight loss trends, GLP-1 agonists are everywhere. In this episode, we unpack the science, social media hype, ethical dilemmas, and side effects surrounding Ozempic, Wegovy, and more. Featuring Dr. Jodie Gee, a Clinical Assistant Professor here at University of Houston College of Pharmacy, and a Ambulatory Care Clinical Pharmacists at Vecino's Denver Harbor Family Clinic, we explore her insights on the role of GLP-1As in patient care. Stay at the end for an in-depth highlight of the newly FDA-approved tirzepatide!

Jessica Brennan, started in the fitness industry 10 years ago as a fitness instructor and personal trainer, realized early on that achieving health goals went beyond physical activity. This realization led Jessica to pursue certifications in nutrition, hormone specialist, and gut health specialist, aiming to address health challenges holistically. Working closely with Karen at Hormone Solutions, Jessica is dedicated to sharing her expertise with women globally. Her areas of expertise include bodybuilding, women's hormone health, personalized nutrition, peptide therapy, and chronic illness management. Jessica is with me this time to discuss our one-year anniversary of being on weight loss peptides. We also created our weight loss peptide group about a year ago which, in addition to our own experiences, has provided us many different points of view on the ups and downs that members face. We'll share personal stories and lessons learned from our community of over 200 members, discussing the use of GLP-1 peptides, strategies for minimizing side effects, and the importance of muscle preservation. We also get into how peptides can improve sleep, athletic performance, and hormonal balance. In this episode: How weight loss peptides and hormone optimization can transform wellness and fitness goals. Optimizing peptide regimens to minimize side effects and prevent muscle loss. Why holistic health approaches are crucial for long-term wellness beyond just weight reduction. Why addressing foundational health practices enhances the success of hormonal treatments. How hormone balance plays a crucial role in weight control and muscle preservation, especially during menopause. Why effort and the right mindset are non-negotiables for achieving fitness goals. How the CAROL Bike can aid in maximizing workout efficiency while using peptides. Why women should progress beyond comfort zones in weightlifting for muscle development. How peptides synergize with training, emphasizing workout efficiency for busy individuals. Why long-term peptide use may be necessary for ongoing health maintenance and weight management. How guilt associated with medication for weight control should be reframed as a preventive health measure. How GLP-1 agonists impact the immune system, mental health, and metabolic functions. Tirzepatide's positive influence on thyroid function. How addressing hormonal imbalances in conjunction with weight loss efforts leads to better outcomes. Why community support can be transformative in the health and fitness journey.   Sponsors Coupon KM20 to get 20% off your order of Vitali Skin Care! Get 40% off your Cozy Earth Bed Sheet with coupon code HORMONES     Are you in peri or post menopause and looking to optimize your hormones and health? At Hormone Solutions, we offer telemedicine services and can prescribe in every U.S. state, as well as in British Columbia, Alberta, and Ontario in Canada.   Visit karenmartel.com to explore our comprehensive programs: Bioidentical Hormone Replacement Therapy Individualized Weight Loss Programs  Peptide Therapy for weight loss    Interested in our NEW Peptide Weight Loss Program? Join today and get all the details here.   Join our Women's Peri and Post Menopause Group Coaching Program, OnTrack, TODAY!   To our nursing audience members, our podcasts qualify for nursing CE @ RNegade.pro. Provide # CEP17654.   Your host: Karen Martel Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert   Karen's Facebook Karen's Instagram

TakeawaysThe podcast features Dr. Grant Tinsley, a body composition expert.The discussion revolves around a case series on body composition effects.GLP-1 receptor agonists are a focus of the research.The importance of resistance training in weight loss is emphasized.Patient case studies provide insights into individual experiences.The first patient lost a significant amount of fat mass while preserving lean mass.The second patient achieved remarkable body composition changes in a short time.The third patient showed positive changes over a longer duration.The need for more randomized trials is highlighted.The conversation underscores the role of exercise and nutrition in weight management.Tap or Click here to see more from Dr. GrantTap here for scientific references in this episode.

Dr. Gillett and James O'Hara discuss a new study on TizepatideFor High-quality labs:► http://sagebio.com/For information on the Gillett Health clinic, lab panels, and health coaching:► https://GillettHealth.comFollow Gillett Health for more content from James and Kyle► https://instagram.com/gilletthealth► https://www.tiktok.com/@gilletthealth► https://twitter.com/gilletthealth► https://www.facebook.com/gilletthealthFollow Kyle Gillett, MD► https://instagram.com/kylegillettmdFollow James O'Hara, NP► https://Instagram.com/jamesoharanpFor 10% off Gorilla Mind products including SIGMA: Use code “GH10”► https://gorillamind.com/For discounts on high-quality supplements►https://www.thorne.com/u/GillettHealth#weightloss #trt #health #glp1 #testosteroneAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

In this special episode on Obstructive Sleep Apnea our host, Dr. Neil Skolnik will discuss treatment of OSA. In Part 1 we discussed and overview of OSA, in Part 2 we discussed making the diagnosis will, and Part 4 will look at cases. This special episode is supported by an independent educational grant from Lilly. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health Dr. Sanjay Patel, M.D, Professor of Medicine, Epidemiology, & Clinical and Translational Science, and Director of the Center for Sleep and Cardiovascular Outcomes Research; Medical Director of the Comprehensive Sleep Disorders Program, University of Pittsburgh Medical Center Selected references: Diagnosis and Management of Obstructive Sleep Apnea - A Review. JAMA. 2020;323(14):1389-1400 Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity. N Engl J Med 2024;391:1193-1205

In this episode of Don't Miss a Beat, hosts Stephen Greene, MD, and Muthiah Vaduganathan, MD, MPH, sit down with Darren McGuire, MD, to explore the groundbreaking results of the SURPASS-CVOT trial. This cardiovascular outcome study is the first to directly compare two incretin-based therapies—tirzepatide, a dual GIP/GLP-1 receptor agonist, and dulaglutide, a GLP-1 receptor agonist—among patients with type 2 diabetes and established atherosclerotic cardiovascular disease (ASCVD). Unlike the placebo-controlled GLP-1 programs of the past decade, SURPASS-CVOT represents a pivotal move toward active comparator trials in cardiometabolic medicine. 00:00:00 Intro 00:01:35 Behind the trial 00:04:35 What is imputed placebo? 00:08:32 The size and scope of SURPASS-CVOT 00:11:01 Results of SURPASS-CVOT 00:14:20 How to select comparators among obesity medicines 00:17:37 Future trials 00:18:56 Interpreting these new kinds of comparisons 00:20:50 Active comparators are the future 00:24:01 Closing

Liver, Lipids, and the Left Ventricle

Dr. Robert Baron explores current strategies for treating obesity, emphasizing evidence-based approaches to diagnosis, lifestyle change, medication, and long-term weight maintenance. He explains the limitations of body mass index (BMI) as a diagnostic tool and highlights the importance of assessing both excess fat and its health consequences. He reviews dietary principles, including calorie reduction, avoiding added sugars, and the importance of sustainable habits over specific diet types. He also discusses the role of physical activity—particularly strength training—for preserving muscle and improving long-term outcomes. Baron evaluates weight loss medications such as semaglutide and tirzepatide, noting their benefits, side effects, and the need for continued use to maintain weight loss. [Health and Medicine] [Show ID: 40757]

Dr. Robert Baron explores current strategies for treating obesity, emphasizing evidence-based approaches to diagnosis, lifestyle change, medication, and long-term weight maintenance. He explains the limitations of body mass index (BMI) as a diagnostic tool and highlights the importance of assessing both excess fat and its health consequences. He reviews dietary principles, including calorie reduction, avoiding added sugars, and the importance of sustainable habits over specific diet types. He also discusses the role of physical activity—particularly strength training—for preserving muscle and improving long-term outcomes. Baron evaluates weight loss medications such as semaglutide and tirzepatide, noting their benefits, side effects, and the need for continued use to maintain weight loss. [Health and Medicine] [Show ID: 40757]

Dr. Robert Baron explores current strategies for treating obesity, emphasizing evidence-based approaches to diagnosis, lifestyle change, medication, and long-term weight maintenance. He explains the limitations of body mass index (BMI) as a diagnostic tool and highlights the importance of assessing both excess fat and its health consequences. He reviews dietary principles, including calorie reduction, avoiding added sugars, and the importance of sustainable habits over specific diet types. He also discusses the role of physical activity—particularly strength training—for preserving muscle and improving long-term outcomes. Baron evaluates weight loss medications such as semaglutide and tirzepatide, noting their benefits, side effects, and the need for continued use to maintain weight loss. [Health and Medicine] [Show ID: 40757]

Dr. Robert Baron explores current strategies for treating obesity, emphasizing evidence-based approaches to diagnosis, lifestyle change, medication, and long-term weight maintenance. He explains the limitations of body mass index (BMI) as a diagnostic tool and highlights the importance of assessing both excess fat and its health consequences. He reviews dietary principles, including calorie reduction, avoiding added sugars, and the importance of sustainable habits over specific diet types. He also discusses the role of physical activity—particularly strength training—for preserving muscle and improving long-term outcomes. Baron evaluates weight loss medications such as semaglutide and tirzepatide, noting their benefits, side effects, and the need for continued use to maintain weight loss. [Health and Medicine] [Show ID: 40757]

Tirzepatide and other GLP-1 medications can be helpful for improving metabolism, but they work best when used thoughtfully. Short-term or low-dose use, combined with balanced hormones, good nutrition, and regular exercise, can lead to better body composition and overall health. Relying on these medications alone especially at a young age can create unnecessary risks and overlook the real lifestyle changes needed for lasting results.Instead of focusing only on the number on the scale, the goal should be to build muscle, reduce excess fat, and give the body the nutrients it needs. For older adults with long-term metabolic issues, a personalized plan that includes GLP-1 therapy, supplements, and strength training can make a big difference. Used as part of a healthy routine rather than a quick fix, these medications can be a valuable tool in supporting long-term wellness.Highlights of the Podcast00:00 – Short-Term vs. Long-Term Use01:23 – Lack of Long-Term Data & Risk of Dependence04:02 – Microdosing for Older Adults05:21 – Realistic Recovery for the Metabolically Broken06:34 – Importance of Personalized Dosing09:18 – Younger Adults Should Focus on Lifestyle First11:36 – Long-Term Caution for Younger Users12:58 – Diet and Hormone Interaction14:09 – Foundation Before Medication16:28 – Responsibility in Supporting the Body

Why does joy feel so scary? Why do we hold back when life is good, waiting for something bad to happen? In this episode, I'm sharing why joy is the most vulnerable emotion we can feel and how that fear keeps us from fully living. We'll talk about why our brains default to “what if it all goes wrong,” how this ties into body image and weight loss, and why you don't need a smaller body to feel joy right now.I'm also giving you a personal update from my birthday and what's making me grateful (and a little nervous!) in this season of life. If you've ever struggled to let yourself be happy without guilt or fear, this one's for you.What you'll learn in this episode: ✔ Why joy is the most vulnerable emotion ✔ How fear of losing happiness sabotages your peace ✔ The connection between body image, weight loss, and joy ✔ Practical tips to embrace joy without waiting for the “perfect” moment

Welcome to a special episode of The Common Sense MD from Performance Medicine! Dr. Rogers sits down with Bo McGregor, FNP for an eye-opening conversation about two of today's game-changing tools in metabolic and hormonal health: testosterone and tirzepatide.Bo shares his personal journey from critical care and ER medicine to a holistic, patient-centered approach—and why he believes he finally found his calling. Together, Dr. Rogers and Bo dig into the myths and realities of hormone replacement (for men AND women), the evolving science behind testosterone therapy, and how misleading traditional nutritional advice set generations on the wrong path.They also unpack the revolutionary impact of tirzepatide for weight loss, metabolic health, and even "turning off food noise," debunking the idea that willpower alone is enough. Listen for practical tips on maximizing these therapies, why muscle-building and protein are crucial at any age, and how lifestyle changes alongside medical intervention can help you reclaim health and longevity.If you're looking for real, evidence-based advice on aging well, getting off unnecessary medications, and living vibrantly, this episode is for you.Highlights:- Debunking testosterone and hormone therapy myths - How tirzepatide is changing obesity and metabolic care - Practical advice for sustainable weight loss and muscle health - Why patients deserve (and can achieve) vitality and feeling "normal" again - The power of integrative, patient-first medicine Disclaimer: This episode does not constitute official medical advice. Please consult a licensed healthcare provider for personalized care.What did you think of this episode of the podcast? Let us know by leaving a review!Connect with Performance Medicine!Check out our new online vitamin store:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://performancemedicine.net/shop/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Sign up for our weekly newsletter: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://performancemedicine.net/doctors-note-sign-up/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@PMedicine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@PerformancemedicineTN⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Performance Medicine

Dr. Centor discusses outcomes in patients with inadequately controlled type 2 diabetes when the dulaglutide dose is escalated versus switching to tirzepatide.

In first-ever study, keto diet scores vs. Parkinson's; Walk away from dementia; Loneliness can kill, but negative social ties can hasten biological aging; Researchers isolate potent memory compound from sage, rosemary; Sketchy knockoff weight loss drugs are flooding the marketplace; The popular vitamin you shouldn't take for sarcoidosis; When osteoporosis is so severe that even minor trauma causes rib fractures.

Titrate, Train, Triumph

Empaveli approved to treat two rare kidney diseases; Elevidys available again for ambulatory patients; Mounjaro shows benefit in cardiovascular disease; wearable cardiac monitor gets clearance; upadacitinib trial shows hair regrowth in individuals with alopecia areata.

In this conversation, I sit down with Nick to unpack the deeper science behind GLP-1s and metabolic health. We explore how compounds like Tirzepatide and GLP-1 agonists go beyond weight loss, influencing everything from cardiovascular elasticity and neuroinflammation to mood, cognition, and gut-brain signaling. We also discuss lesser-known drivers of real change, like adiponectin, MPO, and the surprising effects of statins on inflammation.But the conversation doesn't stop with human health. We dive into the behavioral power of the microbiome, how dogs might reduce childhood allergies, and whether AI can actually translate what your pet is thinking. If you're curious about fat loss, brain health, and the future of metabolic science, this episode offers a perspective you won't find anywhere else.*Chapters:*0:00 – Meet Dr. Nick: From Patient to Pioneer06:50 – The Problem with "Evidence-Based Medicine"10:15 – Why Nick Left the Medical System13:10 – Can YouTube Have a Bigger Impact Than Hospitals?16:30 – What Is Metabolic Health & Why Does It Matter?19:00 – Mental Health, Depression & Metabolism24:15 – Brain Hacks That Actually Work40:00 – Improving Metabolic Flexibility Naturally46:00 – Gut-Brain Connection & Fiber Myths*Nick's Socials + Website*IG: https://www.linkedin.com/in/nicknorwitz/Youtube channel: https://www.youtube.com/channel/UCLTZUJSEulehPtF_ytFiU_AWebsite: https://www.nicknorwitz.com*Kayla's Socials + Website*Instagram: https://www.instagram.com/kaylabarnes/TikTok: https://www.tiktok.com/@femalelongevityTwitter: https://x.com/femalelongevityWebsite: https://www.kaylabarnes.comFollow Her Female Protocol: https://www.protocol.kaylabarnes.comBecome a Member of Kayla's Female Longevity Membership: https://kayla-barnes-lentz.circle.so/checkout/become-a-member

Send us a textWelcome back Rounds Table Listeners! In this throwback episode, Drs. Mike and John Fralick chat about five important research studies published in 2024:Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction (FINEARTS-HF) (0:00 – 4:09)Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity (SURMOUNT-OSA) (4:10 – 9:28)Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes (FLOW) (9:29 – 14:23)Tirzepatide for Metabolic-Dysfunction Associated Steatohepatitis with Liver Fibrosis (SYNERGY-NASH) (14:24 – 20:28)Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections (BALANCE) (20:29 – 23:59)And for the Good Stuff:Toronto Star Santa Claus Fund, Calgary Food Bank, Epilepsy Canada (24:00 - 25:23)Calling keen trainees!Trainees, med students, residents: The Rounds Table and Trial Files (https://trialfiles.substack.com/) are looking for keen individuals to support our efforts.Reach out to fralickmpf@gmail.com if you are interested in getting involved. Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

In this podcast accompanying the August issue of DTB (https://dtb.bmj.com/content/63/8), David Phizackerley (DTB Editor) is joined by James Cave (former DTB Editor-in-Chief). David and James discuss an editorial generated by artificial intelligence (AI) (https://dtb.bmj.com/content/63/8/114) which looks at the role of AI in publishing. They talk about a DTB Forum article (https://dtb.bmj.com/content/63/8/115) that explores some of the practical problems of implementing drug safety alerts.  A DTB Select article (https://dtb.bmj.com/content/63/8/117) provides an overview of a double-blind, randomised, placebo-controlled trial of tirzepatide for weight reduction in people without diabetes. They finish by reviewing the main article (https://dtb.bmj.com/content/63/8/118) that provides an overview of the evidence for lecanemab for the treatment of mild cognitive impairment and mild dementia due to Alzheimer's disease.   Link BMJ policy on AI use: https://www.bmj.com/content/ai-use 

In this episode, Dr. Melody joins the show to discuss the critical role hormones play in weight loss, particularly for women aged 35 to 65. The conversation delves into the misconceptions surrounding hormone replacement therapy and the benefits of using hormones appropriately to support health and well-being.

n this episode, I sat down with my friend and fellow coach, Jess Stancil, to break down all things peptides—what they are, how they work, when to use them, and when not to.We covered:What peptides actually are (and why not everything labeled a peptide really is one)Common options for gut health, inflammation, autoimmune symptoms, cognition, and fat loss—like BPC-157, KPV, TB500, GHK-Cu, and moreWhy peptides aren't a magic fix and should be used as short-term tools—not long-term crutchesOur thoughts on popular GLP-1s like Ozempic and Tirzepatide, plus the potential pros/cons and why dosing, context, and lifestyle matter so muchPeptides for sleep, brain fog, ADHD, and burnout (like Selank and Semax)Where people go wrong with peptide use, especially in the bodybuilding world or when chasing quick fixesAnd how to think about long-term health first—even if performance or fat loss is your goalThis one was a deep dive, but so helpful if you've been curious about peptides and whether they have a place in your health or fitness journey.

The VENTOUX study of endurance athletes, the 10,000 step myth was not busted, rate vs rhythm control for AF, and GLP1 drugs and observational studies are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Endurance Athletes and Arrhythmia (again) VENTOUX trial https://www.ahajournals.org/doi/10.1161/CIRCIMAGING.125.018470 II Daily Step Count and Health — no myths were busted. Lancet Public Health: https://doi.org/10.1016/S2468-2667(25)00164-1 III Rate vs Rhythm Control of AF Medscape: Everyone Deserves a Shot at the American Dream: Sinus Rhythm https://www.medscape.com/viewarticle/everyone-deserves-shot-american-dream-sinus-rhythm-2025a1000jle This Week in Cardiology, July 11, 2025 https://www.medscape.com/viewarticle/1002704 AFFIRM trial https://www.nejm.org/doi/full/10.1056/NEJMoa021328 AFFIRM substudy https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/486560 IV GLP-1 Drugs and Observational Studies Neurodegeneration and Stroke After Semaglutide and Tirzepatide https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2836412 SUSTAIN-6 https://www.nejm.org/doi/full/10.1056/NEJMoa1607141 SELECT Trial https://www.nejm.org/doi/full/10.1056/NEJMoa2307563 You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net

How the STEP-UP trial came to life,  and what made the 7.2mg dose possibleWhat the data actually says about weight loss and side effects at higher dosesWhy trial design, pharmacokinetics, and estimands matter more than you thinkWhat's coming next in obesity meds: duals, triples, and even antagonistsThe real talk on intermittent fasting, access issues, and preaching vs. scienceSign up for Dr. Spencer''s Clinic

If I wanted to gain back 70 pounds, I know exactly what I'd do because I've lived it. In this episode, I'm sharing the habits, behaviors, and sneaky thought patterns that kept me stuck for years…and would absolutely pack the weight back on if I let them. From zombie eating and isolating myself to living in stretchy pants and giving in to my inner fat bitch voice, we're calling it ALL out.If you've been slipping back into these patterns or feel disconnected from yourself, this episode is your wake-up call. 

New Study Alert!

In this episode of the Irresistible You podcast, we're diving into what it means to embrace your cozy or “soft life” era, without the guilt. I used to think that doing cozy things like diamond painting or relaxing at home was lazy… or worse, that stillness would lead to weight gain. I thought if it didn't make money or burn calories, it was a waste of time. But now I know better.I'm sharing how I've started doing things that pull me rather than constantly pushing myself and how that shift has helped me stop emotional eating, feel more grounded, and finally listen to my body. Cozy isn't laziness, it's restoration.If you've ever felt stuck between hustle culture and burnout, this episode is for you.

The Bodybuilding-friendly HRT Clinic - Get professional medical guidance on peptides AND optimizing your health as a man or bodybuilder: [ Pharma Test, IGF1, Tesamorelin, Glutathione, BPC, Semaglutide, Var troche, etc]https://transcendcompany.com/patient-intake-form/?ls=Nyle+NaygaWatch it: https://www.youtube.com/watch?v=6Ihq4tIzyS8&t=5618sRP Hypertrophy Training App: rpstrength.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story  https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'NYLE' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘NYLE' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program:  https://www.nylenaygafitness.comTimestamps:00:00:00 Intro  00:02:40 Personal Life Updates  00:04:51 Pregnancy and Lifestyle Changes  00:10:57 Early Steroid Use and Coaching  00:18:43 Sleep Schedules and Productivity  00:26:45 Bodybuilding Industry Evolution  00:27:52 Modern Bodybuilding Aesthetics  00:37:31 GLP-1 Agonists and Nutrition  00:41:37 Classic Physique and Weight Caps  00:46:51 Coaching and Knowledge Evolution  00:53:07 Family Genetics and Hard Work  00:56:55 Diminishing Returns With Protein  01:08:23 Growth Hormone Dosing Insights  01:16:41 Insulin and GH Combinations  01:22:54 Elite Coaching and Drug Testing  01:27:17 Insulin Resistance Myths  01:32:30 Social Media Arguments01:34:38 Trenbolone and Kidney Concerns  01:39:30 Smart Drug Choices in Bodybuilding  01:49:55 Living In Thailand01:56:35 HGH Timing 02:06:30 Tirzepatide vs. Retatrutide  02:12:00 Prescriptions and Traveling02:16:58 Reversing LVH Growth  02:22:42 Estradiol Levels on Cycle  02:27:04 Anabolic Synonymous Shutdown02:30:45 Classic Physique Drug Use 02:33:40 Life Updates and Fatherhood

Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/

In this episode, I sit down with returning guest Dr. Gabby Gerbino to dig deeper into GLP-1 medications like Ozempic and Tirzepatide. We talk about the side effects most people don't hear about, what to do if you're not responding to the meds, and why sustainable weight loss isn't about eating less—it's about doing things right. If you or someone you love is considering or currently using GLP-1s, this episode will help you navigate your journey with better questions, better strategy, and way less misinformation.HOW TO FIND DR. GERBINO:Book An Appointment: https://www.zocdoc.com/doctor/gabrielle-gerbino-md-552785?fbclid=IwZXh0bgNhZW0CMTAAAR1q4mVKJOAdejs0ItOa-AEImDKXZFdSwrYji-cKVLOlYUeMo98CUCXQ1ls_aem_ZFil8u0r_hDBLVr34hW3EgFIT40 LINKS✅ Want some free workouts to get you started on your fitness journey?Check out the FIT40 Toned In 20 Workouts by clicking here: https://fit40coaching.com/20✅ Do you thrive on monthly challenges and group support?Check out FIT40 Group Coaching by clicking this link: https://coach.everfit.io/package/BG758131​✅ Need professional level 1:1 accountability to help you finally reach your goals?Check out FIT40 Coaching by clicking this link: https://fit40coaching.com/AFFILIATE LINKS:Try Tonal for 30 Days Risk Free: https://tonal.sjv.io/FIT40Get 10% Off The Genius Protein Shot: https://www.geniusshot.com/?ref=BRYAN_FIT40&transaction_id=10214dd14c839e450a4423af7b1f8eCONNECT WITH ME ONLINEFacebook: https://www.facebook.com/bryan.fitzsimmonsInstagram: ⁠⁠⁠⁠https://www.instagram.com/coach_fitzz/⁠⁠⁠⁠Tiktok: ⁠⁠⁠⁠⁠https://www.tiktok.com/@coach_fitzz?is_from_webapp=1&sender_device=pcYoutube: https://www.youtube.com/@bryan_fit40 This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit bryanfitzsimmon.substack.com

Kann man den Hunger einfach wegspritzen? Und was passiert eigentlich, wenn du plötzlich keinen Appetit mehr hast?Die Medien sind voll von Mythen, Halbwissen und Marketing rund um Ozempic, Wegovy und anderen der sogenannten „Abnehmspritzen“. In dieser Episode bekommst du den Überblick, den du brauchst – um Dir eine eigene Meinung zu bilden.Du erfährst:warum viele Menschen nicht zunehmen, obwohl sie mehr essen – und andere schon bei normalen Portionen zunehmen,was GLP-1-Wirkstoffe mit Spielsucht, Alkohol und impulsivem Verhalten zu tun haben,warum viele Patienten nach dem Absetzen der Spritze schneller wieder zunehmen, als sie abgenommen haben,und warum es gefährlich sein kann, unter diesen Medikamenten zwar Gewicht zu verlieren – aber dabei Muskeln zu verbrennen statt Fett.Und wenn Du ohnehin sagst: „Spritze? Kommt für mich nicht infrage“, lohnt diese Episode – weil sie Dir hilft, den Mechanismus hinter Hunger, Sättigung und Gewohnheiten besser zu verstehen. Und damit auch Deinen eigenen Körper effektiver zu steuern.____________*WERBUNG: Infos zum Werbepartner dieser Folge und allen weiteren Werbepartnern findest Du hier.____________Mehr zum Thema:Podcast: Folge 502: Ratgeber Nahrungsergänzung – mit Ernährungsmediziner Niels Schulz-RuhtenbergQuellen:Wilding, J. P. H. et al. (2021). Once-weekly semaglutide in adults with overweight or obesity. New England Journal of Medicine, 384(11), 989–1002.Garvey, W. T. et al. (2022). Two-year effects of semaglutide in adults with overweight or obesity: The STEP 5 trial. Nature Medicine, 28(10), 2083–2091.Jastreboff, A. M. et al. (2022). Tirzepatide once weekly for the treatment of obesity. New England Journal of Medicine, 387(3), 205–216.Ryan, D. H. & Yockey, S. R. (2017). Weight loss and improvement in comorbidity: Differences at 5%, 10%, 15%, and over. Current Obesity Reports, 6(2), 187–194.Marx, N. et al. (2022). GLP-1 receptor agonists for the reduction of atherosclerotic cardiovascular risk in patients with type 2 diabetes. Circulation, 146(24), 1882–1894.Lincoff, A. M. et al. (2023). Semaglutide and cardiovascular outcomes in obesity without diabetes. New England Journal of Medicine, 389(24), 2221–2232.Karakasis, P. et al. (2023). Effect of tirzepatide on renal function in type 2 diabetes: A systematic review. Diabetes, Obesity and Metabolism.Ida, S. et al. (2021). Effects of antidiabetic drugs on muscle mass in type 2 diabetes mellitus. Current Diabetes Reviews, 17(3), 293–303.Wilding, J. P. H. et al. (2021). Impact of semaglutide on body composition in adults with overweight or obesity: Exploratory analysis of the STEP 1 study. Journal of the Endocrine Society, 5(Suppl. 1), A16–A17.Gorgojo-Martínez, J. J. et al. (2022). Clinical recommendations to manage gastrointestinal adverse events in patients treated with GLP-1 receptor agonists: A multidisciplinary expert consensus. Journal of Clinical Medicine Research, 12(1).Tantawy, S. A. et al. (2017). Effects of physical activity and diet control to manage constipation in middle-aged obese women. Diabetes, Metabolic Syndrome and Obesity, 10, 513–519.Jastreboff, A. M. et al. (2023). Triple–hormone-receptor agonist retatrutide for obesity — A phase 2 trial. New England Journal of Medicine, 389(6), 514–526.***Shownotes und Übersicht aller Folgen.Trag Dich in Marks Dranbleiber Newsletter ein.Entdecke Marks Bücher.Folge Mark auf Instagram, Facebook, Strava, LinkedIn. Hosted on Acast. See acast.com/privacy for more information.

What do Zumba and Greek dancing have to do with bone density? Why should you shave first and soak later? And who gets to decide whether you can have a hysterectomy for health reasons if you haven’t had kids yet? In this episode, Endocrinologist Dr Sonia Davison from Jean Hailes for Women’s Health talks about whether diet and exercise can prevent dementia and what waist circumference has to do with healthy ageing. She also discusses how stomping, sleeping and strength training should all be part of the puzzle as you get older. We also talk about intermittent fasting and how cups of tea with your girlfriends could be just what the doctor ordered. And, is it possible to delay your ‘hormone window of chaos’? THE END BITS For more information on bone density Dr Sonia Davison recommends: Healthy Bones Australia For more information on fibroids Dr Mariam recommends: ask4ufe Sign up to the Well Newsletter to receive your weekly dose of trusted health expertise without the medical jargon. Ask a question of our experts or share your story, feedback, or dilemma - you can send it anonymously here, email here or leave us a voice note here. Ask The Doc: Ask us a question in The Waiting Room. Follow us on Instagram and Tiktok. All your health information is in the Well Hub. Support independent women’s media by becoming a Mamamia subscriberCREDITS Hosts: Claire Murphy and Dr MariamGuest: Dr Sonia DavisonSenior Producers: Claire Murphy and Sasha TannockAudio Producer: Scott Stronach Mamamia studios are styled with furniture from Fenton and Fenton. Visit fentonandfenton.com.au Mamamia acknowledges the Traditional Owners of the Land we have recorded this podcast on, the Gadigal people of the Eora Nation. We pay our respects to their Elders past and present, and extend that respect to all Aboriginal and Torres Strait Islander cultures.Information discussed in Well. is for education purposes only and is not intended to provide professional medical advice. Listeners should seek their own medical advice, specific to their circumstances, from their treating doctor or health care professional.See omnystudio.com/listener for privacy information.

Is there a better, safer, FREE alternative to Ozempic (and other GLP-1 drugs)? In this episode of Walk, Don't Run to the Doctor, Miles Hassell MD reacts to the growing buzz and shares a time-tested, evidence-based 3-step plan that outperforms popular weight loss drugs in the long run. As GLP-1 drugs like Ozempic, Wegovy, and Mounjaro surge in popularity, Dr. Hassell offers critical insight into their risks—like muscle loss, pancreatic complications, and long-term unknowns—while proposing a practical, natural alternative for lasting weight loss and better metabolic health. Key Takeaways: Why Big Pharma's track record with weight loss drugs demands caution The secret 3-step plan: Eat 6 servings of fruits & veggies, 3 minutes of daily exercise, reduce refined carbs Bonus tips: Bust cravings by eating protein with every meal, daily probiotics, and unlock the power of preemptive eating Why this plan costs nothing, has zero side effects, and starts showing results in just one week A timely message in light of the weight loss drug headlines—who should be in control of your health?  More references can be found at www.GreatMed.org Get your copy of Good Food Great Medicine. https://a.co/d/ajAzYzo Would you like Dr. Hassell to answer your question on the air? Contact us! Phone/text: 503-773-0770 e-mail: info@GreatMed.org Write us a letter. We love to hear from you. This podcast is sponsored by our generous listeners. Send questions, comments, and support to: 4804 NW Bethany Blvd., Suite I-2, #273 Portland OR 97229 References: Chen, X., et al. (2025). Association of dietary fiber intake with all-cause and cardiovascular mortality in diabetes and prediabetes. Diabetology & metabolic syndrome, 17(1), 231. https://pubmed.ncbi.nlm.nih.gov/40533827/   Look, M., et al. (2025). Body composition changes during weight reduction with tirzepatide in the SURMOUNT-1 study of adults with obesity or overweight. Diabetes, obesity & metabolism, 27(5), 2720–2729. https://pubmed.ncbi.nlm.nih.gov/39996356/   Wilding, J., et al. (2021). Once-Weekly Semaglutide in Adults with Overweight or Obesity. The New England journal of medicine, 384(11), 989–1002. https://pubmed.ncbi.nlm.nih.gov/33567185/   Tinsley, G. M., & Heymsfield, S. B. (2024). Fundamental Body Composition Principles Provide Context for Fat-Free and Skeletal Muscle Loss With GLP-1 RA Treatments. Journal of the Endocrine Society, 8(11),https://pubmed.ncbi.nlm.nih.gov/39372917/    Neeland, I. J., et al. (2024). Changes in lean body mass with glucagon-like peptide-1-based therapies and mitigation strategies. Diabetes, obesity & metabolism, 26 Suppl 4, 16–27. https://pubmed.ncbi.nlm.nih.gov/38937282/   Sato, M., et al. (2023). Relationships among Postprandial Plasma Active GLP-1 and GIP Excursions, Skeletal Muscle Mass, and Body Fat Mass in Patients with Type 2 Diabetes Treated with Either Miglitol, Sitagliptin, or Their Combination: A Secondary Analysis of the MASTER Study. Journal of clinical medicine, 12(9), 3104. https://pubmed.ncbi.nlm.nih.gov/37176545/   Monami, M., et al. (2017). Safety issues with glucagon-like peptide-1 receptor agonists (pancreatitis, pancreatic cancer and cholelithiasis): Data from randomized controlled trials. Diabetes, obesity & metabolism, 19(9), 1233–1241. https://pubmed.ncbi.nlm.nih.gov/28244632/   Anderson, S. L., & Trujillo, J. M. (2010). Association of pancreatitis with glucagon-like peptide-1 agonist use. The Annals of pharmacotherapy, 44(5), 904–909. https://pubmed.ncbi.nlm.nih.gov/20371755/   Kapoor, I., Sarvepalli, S. M., D'Alessio, D., Grewal, D. S., & Hadziahmetovic, M. (2023). GLP-1 receptor agonists and diabetic retinopathy: A meta-analysis of randomized clinical trials. Survey of ophthalmology, 68(6), 1071–1083. https://pubmed.ncbi.nlm.nih.gov/37454782/   Bikou, A., et al. (2024). A systematic review of the effect of semaglutide on lean mass: insights from clinical trials. Expert opinion on pharmacotherapy, 25(5), 611–619. https://pubmed.ncbi.nlm.nih.gov/38629387/   Jalleh, R. J., et al. (2024). Clinical Consequences of Delayed Gastric Emptying With GLP-1 Receptor Agonists and Tirzepatide. The Journal of clinical endocrinology and metabolism, 110(1), 1–15. https://pubmed.ncbi.nlm.nih.gov/39418085/   Berg, S. AMA. (2023). Questions patients may have about weight-loss drugs. https://www.ama-assn.org/delivering-care/public-health/questions-patients-may-have-about-weight-loss-drugs   Friedman, J. (2025). America's up-and-down history with weight-loss drugs. https://www.history.com/articles/weight-loss-drugs-america    

Are you navigating the stormy seas of menopause? Wondering how to tackle bloating and breakthrough bleeding? Curious about the mysteries of hormone therapy and why traditional treatments may not work for everyone? This second-part Q&A episode is packed with real-life stories and expert advice to answer your questions! Ever wondered how hormone levels, thyroid function, and gut health intertwine during menopause? What about the innovative strategies that can help with weight loss resistance? Discover why personalized solutions are key to thriving through hormonal shifts and learn how to biohack your way to better health. From managing stress-induced hormone fluctuations to the unexpected role of melatonin, this episode has it all. What adjustments can you make to your hormone replacement therapy during stressful times? And how can peptides help in your weight loss journey? Dive into these topics and more! In this episode, we uncover: How hormone imbalances can cause bloating, plus how to address them effectively. Why personalized hormone therapy is crucial for women with unique health challenges. How innovative peptides can help overcome weight loss resistance and enhance results. Why adjusting hormone therapy during stress is vital for managing menopause symptoms. How melatonin plays a multifaceted role in menopause beyond just aiding sleep. Don't miss out on these transformative insights. Tune in now to empower your journey through menopause and discover solutions that truly work for you!     Sponsors Get our Estro Vitality and Progest Sleep Hormone Oils and get 25% off. Coupon KM20 to get 20% off your order of Vitali Skin Care! Use my link to save 20% at GETKION.COM/HORMONE     Are you in peri or post menopause and looking to optimize your hormones and health? At Hormone Solutions, we offer telemedicine services and can prescribe in every U.S. state, as well as in British Columbia, Alberta, and Ontario in Canada.   Visit karenmartel.com to explore our comprehensive programs: Bioidentical Hormone Replacement Therapy Individualized Weight Loss Programs  Peptide Therapy for weight loss    Interested in our NEW Peptide Weight Loss Program? Join today and get all the details here.   Join our Women's Peri and Post Menopause Group Coaching Program, OnTrack, TODAY!   To our nursing audience members, our podcasts qualify for nursing CE @ RNegade.pro. Provide # CEP17654.   Your host: Karen Martel Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert   Karen's Facebook Karen's Instagram

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Welcome back to Diamond Paint and Podcast — where I ramble, reflect, and real-talk my way through a diamond painting session.In this episode, we're all over the place in the best way possible. I'm chatting about:The “Donut Mom” at cheerleading

It's only June. That means you still have six full months to change your life. Seriously. Who do you want to be when the ball drops on December 31st?Are you going to be crying in the bathroom again because nothing fits? Googling “how to lose weight fast” for the hundredth time? Or are you going to feel proud as hell that you didn't give up on yourself this time?In this episode, I'm talking about what's actually possible in six months and how showing up with consistency (not perfection!) can transform how you feel, how you live, and how you see yourself.If you're tired of starting over every Monday, hating your life, emotionally eating your days away, and waiting for “the right time,” this is your wake-up call.Let's talk about who you could be by the end of the year and how to start becoming her now.

Today we do a round-up of some of the recent semaglutide trials. Does semaglutide ever miss? But what about tirzepatide, which causes even more weight loss?We also review two new critical care trials, FLUID and the UK-ROX, new platelet transfusion guidelines, and a new retrospective study of apixaban vs rivaroxaban vs warfarin. Oral Semaglutide for Diabetes with Cardiovascular Disease or CKD (SOUL)Semaglutide for Peripheral Artery Disease (STRIDE)Semaglutide for MASH (ESSENCE)Semaglutide vs Tirzepatide for Obesity (SURMOUNT-5)Normal Saline vs Lactated Ringers (FLUID)Conservative Oxygen Targets in Mechanically Ventilated Patients (UK-ROX)Platelet Transfusion GuidelinesApixaban vs Rivaroxaban vs Warfarin Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R

In this quick hits episode, you are going to hear a clip from my most downloaded episode to date! I take a deep dive into the world of GLP-1s, the revolutionary weight loss medications that have captivated the health and wellness scene. We all know that whenever there's a new breakthrough, doubts and controversies tend to emerge, leaving us wondering if it's too good to be true. But fear not! In this show, I am here to unravel the mysteries and shed light on these drugs like never before. My goal is to address your concerns, provide clarity, and empower you with the knowledge to make informed decisions. I will share my own journey on tirzepatide plus client experiences. Whether you're considering these medications or simply seeking accurate information, this episode will be your ultimate resource. So sit back, relax, and join me on this captivating journey into the realm of GLP-1s. By the end of this podcast, you'll have a comprehensive understanding of the pros and cons, equipping you with the insights to navigate this topic with confidence. It's time to separate the facts from the myths and arm yourself with the information you need. Listen to the full episode here.   Sponsors Get $100 off your CAROL bike with coupon code HORMONE here.     Are you in peri or post menopause and looking to optimize your hormones and health? At Hormone Solutions, we offer telemedicine services and can prescribe in every U.S. state, as well as in British Columbia, Alberta, and Ontario in Canada.   Visit karenmartel.com to explore our comprehensive programs: Bioidentical Hormone Replacement Therapy Individualized Weight Loss Programs  Peptide Therapy for weight loss    Interested in our NEW Peptide Weight Loss Program? Join today and get all the details here.   Join our Women's Peri and Post Menopause Group Coaching Program, OnTrack, TODAY!   To our nursing audience members, our podcasts qualify for nursing CE @ RNegade.pro. Provide # CEP17654.   Your host: Karen Martel Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert   Karen's Facebook Karen's Instagram