Podcasts about Prospective

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Best podcasts about Prospective

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Latest podcast episodes about Prospective

Zero to Profitable Franchise
How Much Does McDonald's Make?

Zero to Profitable Franchise

Play Episode Listen Later Dec 1, 2025 9:11


Grab our breakdown of the 5 Low-Cost Businesses That Make $1 Million: https://www.franchiseempire.com/lowcost?utm_source=FENov302025Also, if you liked this video, but don't think the food industry is for you, check out this tool shop business breakdown: https://youtu.be/5jqCWyUq8ccIf you liked this video, but think a food franchise is too expensive, check out this video to find a better opportunity for you: Ever wondered how much money McDonald's franchise owners actually make? In this video, we reveal what it really costs to open a McDonald's, how much franchisees are paying in royalties and rent, and the surprising way McDonald's makes most of its money (hint: it's not burgers). We'll also break down how their average $4M revenue stacks up against other fast food giants and whether owning one is worth the $2 million+ investment.If you're considering investing in a fast food franchise or exploring business opportunities with big potential, this one's a must-watch.------------------Considering Investing In A Franchise?

The Profitable Play Podcast
345: 9 Things I'd Tell A Prospective Play Cafe Owner If I Was NOT Afraid To Hurt Their Feelings

The Profitable Play Podcast

Play Episode Listen Later Nov 28, 2025 36:50


In this episode, I'm sharing the exact tough-love truth I give my one-on-one clients inside Play Cafe Academy and Playmaker Society—the things I say privately that genuinely help people avoid incredibly expensive, stressful, and sometimes irreversible mistakes when opening an indoor playground or play café.This audio is pulled directly from a YouTube video I recently published, and I wanted to share it here because it's that important. But if you want to make sure you never miss content that doesn't make it over to the podcast feed, be sure to subscribe to my YouTube channel as well.If you're in the planning phase, this is the reality check you need before signing a lease, building a business plan, launching a GoFundMe, choosing a location, or assuming open play alone will carry your business. I walk through the most common misconceptions I see every week—unrealistic revenue projections, relying too heavily on vendors, expecting your customers to be loyal, thinking you can bring your kids to work, underestimating the impact on your relationship, and more.I'm also diving into why no one wants to fund your dream, how crowdfunding can work when used as a marketing strategy (not a funding plan), and why your startup budget, projected revenue, and marketing spend need to align if you want the business to be sustainable and your life to stay intact.My intention isn't to scare you—it's to give you the full, unfiltered picture so you can move forward with clarity, confidence, and realistic expectations. A play café can absolutely be profitable and joyful, but only if it's built on truth, not wishful thinking.If you enjoyed this episode and want a part two for current owners, send me a message or leave a review.RESOURCES MENTIONED:Business Plan ToolkitWhy You Can't Bring Your Kids To Work What Opening an Indoor Playground CostsOTHER RESOURCES:Play Cafe Academy & Play Makers SocietyGetting Started With Your Play Cafe [YouTube Video Playlist]What's Working In The Indoor Play Industry 2025 GuideFund Your Indoor Play Business [Free Training]Indoor Play Courses & 1:1 Consulting WaitlistMichele's InstagramMichele's WebsitePlay Cafe Academy YouTube ChannelETSY Template ShopPrepare Your Indoor Playground For a RecessionPlay Cafe Academy & Play Makers SocietyQuestions and Support: Support@michelecaruana.com Play Cafe Academy & Play Makers Society: http://bit.ly/3HES7fDQuestions and Support: Support@michelecaruana.com Simplify and Scale with 50% OFF WellnessLiving: https://discover.wellnessliving.com/playcafeacademyActive Campaign Free Trial: https://www.activecampaign.com/?_r=D6IYK3HG

Zero to Profitable Franchise
Franchise Experts Break Down The Reality of Franchising

Zero to Profitable Franchise

Play Episode Listen Later Nov 27, 2025 68:04


Download our list of 42 High Performing (and profitable) Franchises: https://www.franchiseempire.com/42hpf?utm_source=TJnov252025If you like this video and want to learn how to fund your business, check out this video: https://youtu.be/VQhnGLuHDTsThinking about buying a franchise in 2025? Wondering if you can keep your job and still make passive income from a semi-absentee franchise? In this video, we reveal the hard truth about passive franchise ownership and break down the biggest mistakes people make when choosing a franchise business model. You'll also learn the pros and cons of brick & mortar vs. service-based franchise opportunities and what works best for first-time buyers. Whether you're researching the best franchises to own or comparing business ideas that make real money, this episode will help you avoid costly errors and choose the right path.------------------Considering Investing In A Franchise?

Zero to Profitable Franchise
Should You Buy this $250K business in 2025?

Zero to Profitable Franchise

Play Episode Listen Later Nov 26, 2025 9:08


Download our list of 42 High Performing (and profitable) Franchises: https://www.franchiseempire.com/42hpf?utm_source=TJnov252025If you like this video and want to learn how to fund your business, check out this video: https://youtu.be/VQhnGLuHDTsServPro might not be the first franchise that comes to mind, but with over 2,300 locations and a 22-year streak as the top restoration brand, it should be. In this video, I break down the real startup costs, franchise fees, and the surprising lack of sales data. You'll also learn how the brand grew from a small painting business into a national leader and what that means for you as an investor. We'll talk about why ServPro's recession-resistant model stands out and why getting a territory now might be nearly impossible. If you're considering service-based franchises or want a business backed by insurance demand, this is one to watch closely.------------------Considering Investing In A Franchise?

JACC Speciality Journals
Multicenter Prospective Assessment of Coronary Microvascular Dysfunction: Primary Results of the FlowLab Study | JACC: Advances

JACC Speciality Journals

Play Episode Listen Later Nov 26, 2025 2:54


Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Multicenter Prospective Assessment of Coronary Microvascular Dysfunction: Primary Results of the FlowLab Study.

Objectif TECH
Écoutons le futur : La nouvelle course à l'espace, notre futur en orbite ?

Objectif TECH

Play Episode Listen Later Nov 25, 2025 43:01


La course à l'espace ne se joue plus seulement sur la Lune mais en orbite basse ; partout dans le monde des constellations de satellites sont déployées : le New Space redéfinit aujourd'hui les règles du jeu et marque une rupture dans la manière de concevoir, produire et exploiter les satellites. Cette dynamique, portée par des acteurs privés et des innovations majeures, impose une cadence industrielle et redéfinit l'équilibre des puissances dans le secteur spatial et pose de nouvelles questions, comment garantir la souveraineté européenne, organiser la coopération entre acteurs publics et privés, et préserver un espace durable ?Dans cet épisode d'Écoutons le Futur, quatre experts de l'industrie spatiale décryptent cette révolution : miniaturisation des satellites, industrialisation, convergence technologique. Ils analysent les impacts sur la filière, les risques liés à la privatisation et à la densification des satellites, et les solutions pour structurer une gouvernance efficace. Un débat riche sur la manière dont l'Europe peut rester dans la course et peser dans la définition des futures règles du spatial.Présents sur notre plateau :- Guillaume Scottez, Vice Président Innovation chez Eutelsat- Pierre Bertrand, CEO et cofondateur de SkyNoPy- Théophile Lagraulet, CEO et cofondateur de SpaceLocker- Patrice Duboé, directeur des technologies et de l'innovation pour le secteur Aérospatial et défense chez CapgeminiUne émission animée par Valère CorréardDécouvrez notre accompagnement dans le secteur spatial

Keep What You Earn
Making Accountability Part of Your Culture with Gina Cotner

Keep What You Earn

Play Episode Listen Later Nov 24, 2025 53:26


Today, I'm joined by Gina Cotner, founder and CEO of Athena Executive Services. Gina shares her journey from executive assistant to building one of the top virtual assistant firms in the country. We talk about how to create real accountability on your team, delegate effectively, and build a business that doesn't depend on you doing everything yourself. Gina gives practical, no-fluff advice on managing both remote and in-office teams while keeping productivity and trust high. If you're ready to lead better and free yourself from burnout, this episode is a must-listen.   What you'll hear in this episode: [02:25] Gina's Journey: From Executive Assistant to CEO [03:00] The Importance of Delegation in Business Growth [06:55] Overcoming Barriers to Effective Delegation [19:45] The Role of Accountability in Team Management [27:50] Setting Expectations and Accountability [30:05] Leveraging Resources to Meet Deadlines [33:15] Building a Culture of Accountability [37:15] Effective Communication and Trust [40:20] Hiring and Vetting for Cultural Fit [49:30] Remote Management Best Practices   If you like this episode, check out: Think Bigger Than a Niche Your Most Expensive Habit Why Enterprise Value is the Goal   LinkedIn: Gina Cotner Website: https://www.athenaexecutiveservices.com Prospective clients are encouraged to schedule a conversation with Jennifer Tracy from Athena Executive Services to explore what kind of VA support best fits their business   Learn more about our CFO firm and services: https://www.keepwhatyouearn.com/   Connect with Shannon: https://www.linkedin.com/in/shannonweinstein Watch full episodes: https://www.youtube.com/channel/UCMlIuZsrllp1Uc_MlhriLvQ Follow along on IG: https://www.instagram.com/shannonkweinstein/   The information contained in this podcast is intended for educational purposes only and is not individual tax advice. We love enthusiastic action, but please consult a qualified professional before implementing anything you learn.

Zero to Profitable Franchise
How Much Does It Cost To Open a Pizza Hut? (Costs, Sales, & Fees)

Zero to Profitable Franchise

Play Episode Listen Later Nov 23, 2025 10:33


Download our list of 42 High Performing (and profitable) Franchises: https://www.franchiseempire.com/42hpf?utm_source=TJnov222025Pizza Hut might bring back memories, but does it still deliver when it comes to making money? In this breakdown, I cover the startup costs, royalties, and average sales for each type of Pizza Hut location. I also unpack whether the investment makes sense based on real numbers from their latest FDD, and throw in a few wild facts (like what topping went to space). If you're thinking about owning a franchise or just want to understand the business behind iconic brands, this is one worth watching.------------------Considering Investing In A Franchise?

Specifically for Seniors
Postcards to Voters with Tony the Democrat

Specifically for Seniors

Play Episode Listen Later Nov 23, 2025 56:15


Welcome to Specifically for Seniors! Today we're delighted to introduce Tony McMullen, affectionately known as “Tony the Democrat.” His story is one of those rare grassroots adventures that begins small and blossoms into something extraordinary. Back in March of 2017, Tony invited just five friends over to handwrite postcards reminding voters about an upcoming election. Five friends, five postcards each—that was it. Yet within a month, that modest gathering had sparked a nationwide movement of 1,200 volunteers who together wrote more than 51,000 postcards. Fast forward to today, and Postcards to Voters has grown into a vibrant community of over 162,000 volunteers across all 50 states, who have collectively sent more than 22 million handwritten postcards to support critical elections.What makes this effort so special is its personal touch. These aren't form letters or computer printouts. Every single postcard is handwritten, often decorated, and mailed by volunteers who want to make a real difference. And it works. Candidates have won races by margins as slim as 95 votes thanks to postcard outreach. Beyond the victories, Tony emphasizes that the friendships, connections, and sense of purpose that volunteers discover along the way have been the most beautiful unintended gift of all.The impact has been remarkable across hundreds of races. Karen Gaddis in Oklahoma won by just 95 votes. Phil Miller in Iowa saw his campaign office windows covered with postcards from volunteers nationwide. Kevin Cavanaugh in New Hampshire won by fewer than a thousand votes. In recent cycles, Postcards to Voters has supported successful recent statewide campaigns in Georgia, Pennsylvania, and New Jersey, with nearly all supported candidates prevailing. Even in tough red districts where victories were elusive, the postcards built foundations for future campaigns and inspired local activists. Getting involved is simple and flexible. Prospective volunteers email Join@tonythedemocrat.org, submit a photo of a sample postcard to show legibility, and once approved can request addresses anytime through Abby the Address Bot. The genius of the program is its three-day commitment system: volunteers only take as many addresses as they can complete within three days, whether that's five postcards or fifty. There are no quotas, no pressure, and volunteers can request more addresses immediately after finishing or take breaks between campaigns. Postcards are designed to look like personal mail—neutral or friendly in style, without campaign logos—so recipients are more likely to read them rather than dismiss them as political junk.Tony reminds us that every campaign is a success because the true goal is strengthening the habit of voting among Democrats, not just winning individual races. The organization is entirely volunteer-run, with no salaries or office space, relying on modest donations to cover technology costs. With around 300 campaigns requesting help each November alone, there is always need for more hands. Even writing just five postcards a month makes a meaningful contribution to this grassroots movement that has become one of the most effective tools for voter outreach nationwide.Learn more and sign up at Postcardstovoters.org to join this inspiring community of volunteers making democracy work one handwritten postcard at a time.

Zero to Profitable Franchise
How Much to Open a Fast Food Franchise? (KFC costs, sales, & Fees)

Zero to Profitable Franchise

Play Episode Listen Later Nov 22, 2025 9:00


Is opening a KFC franchise still a smart move in 2025? In this video, we break down the numbers behind one of the most iconic fast-food brands in the world. You'll learn the startup costs, average sales per unit, royalty fees, and whether it's worth the $1.8M+ investment. We also dive into the untold story behind Colonel Sanders' rise and explore why KFC has 3X more stores in China than in the U.S. If you're even thinking about food franchising, don't skip this.Considering Investing In A Franchise?

Zero to Profitable Franchise
How To Easily Buy a Franchise (step-by-step)

Zero to Profitable Franchise

Play Episode Listen Later Nov 21, 2025 6:08


Grab our breakdown of the 5 Low-Cost Businesses That Make $1 Million: https://www.franchiseempire.com/lowcost?utm_source=FEnov202025Anyone can Google a franchise. But what you don't get from a search is the real strategy, emotional support, and industry respect that comes with going through the process with a broker. Franchise buyers don't always realize how much strategy and support go into making the right choice. In this episode, we talk about what really happens behind the scenes, from how brands treat broker-vetted candidates to the emotional rollercoaster most buyers face. If you're exploring franchise ownership, this will help you see the full picture.------------------Considering Investing In A Franchise?

Relentless Health Value
Take Two: EP240: A Direct Contracted and Actually High-Value Network That Elizabeth Mitchell From PBGH Talked About, With Olivia Ross

Relentless Health Value

Play Episode Listen Later Nov 20, 2025 34:32


This OG of directly contracted high-value networks or Centers of Excellence networks came up, name dropped and everything in the episode with Elizabeth Mitchell from PBGH, the Purchaser Business Group on Health, from two weeks ago. That was episode 491. So, welcome to this deep cut episode with Olivia Ross from way back, pre-pandemic times. This episode of Relentless Health Value revisits the concept of directly contracted high value networks or Centers of Excellence (ECEN) with Olivia Ross. The discussion explores the impact and potential of the ECEN network, emphasizing the importance of quality, price transparency, and multidisciplinary approaches in healthcare.  Olivia delves into the reasons why ECEN was significant in past PBGH projects and its current relevance, despite its eventual dismantling due to corporate changes. The episode highlights the benefits for employers in creating their own high-value networks and the positive outcomes from fewer unnecessary surgeries and better quality care. Additionally, it covers the rigorous process of selecting Centers of Excellence and how continuous quality improvement efforts benefit both employers and healthcare providers. === LINKS ===

Jack Westin MCAT Podcast
Experimental vs Observational Studies: MCAT Psych/Soc MASTERCLASS

Jack Westin MCAT Podcast

Play Episode Listen Later Nov 18, 2025 56:44


In this episode of the Jack Westin MCAT Podcast, Mike and Molly break down one of the highest-yield (and most commonly missed) topics in the entire Psych/Soc section:→ Experimental vs. Observational research→ When you can (and CANNOT) conclude causality→ Cross-sectional vs. longitudinal→ Cohort vs. case-control vs. case studies→ Prospective vs. retrospective→ Validity vs. reliability (internal vs. external + the dartboard analogy)→ Real AAMC examples (including the cocaine exposure passage)→ Classic studies: Phineas Gage, H.M., Milgram, Little Albert, Asch, Bobo doll, and moreIf you've ever picked the “causes” answer choice on an observational study and gotten wrecked, this episode is for you. Skill 3 (reasoning about research design & execution) shows up in EVERY section, but Psych/Soc is where it can make or break your score.Want to learn more? Shoot us a text at 415-855-4435 or email us at podcast@jackwestin.com!

Daybreak
Princeton Students' Prospective Summer Plans, the University's New Recording Policy, and Princeton Women's Field Hockey Advances to the Final Four — Tuesday, Nov. 18

Daybreak

Play Episode Listen Later Nov 18, 2025 3:26


Today, we talk to Princeton students about their prospective summer plans, look at the University's new recording policy, and cover the Princeton women's field hockey advancement to the Final Four of the NCAA final championship.

Combats (Baleine sous Grav... SUR le front)
S05E31 2049 : Ce que le climat va faire à l'Europe 3/4, les points de bascule (Nathanaël Wallenhorst)

Combats (Baleine sous Grav... SUR le front)

Play Episode Listen Later Nov 18, 2025 19:31


Objectif TECH
Durable - Adaptation climatique : de l'urgence aux solutions pour les infrastructures et territoires

Objectif TECH

Play Episode Listen Later Nov 18, 2025 26:49


L'inaction face au changement climatique coûte déjà plus cher que la transition, selon l'un des rapports de la Cour de Comptes de 2025. Dans cet épisode, nos invités de SNCF Réseau et du CEREMA décryptent comment collectivités et opérateurs d'infrastructures transforment cette urgence en actions concrètes.Au-delà des réponses techniques, l'épisode met aussi en lumière le paradoxe de l'adaptation :  déployée localement pour répondre aux besoins des territoires, elle doit pourtant être pensée de manière systémique, car le changement climatique ignore les frontières. Les interviewés détaillent les outils existants et les perspectives offertes par la technologie pour modéliser les scénarios, coordonner les acteurs et garantir la continuité des services. Un message résolument optimiste : pour chaque défi, des solutions existent, à condition d'agir collectivement.Un échange animé par Valère Corréard avec Benoît Chevalier, Directeur de la stratégie d'adaptation au changement climatique de SNCF Réseau, Pascal Berteaud, Directeur général du CEREMA, et Maëlle Bouvier, Directrice du développement durable pour le secteur public chez Capgemini Invent.

Zero to Profitable Franchise
Why You Should NOT Buy a Hotel Franchise (Costs, Sales, & Fees)

Zero to Profitable Franchise

Play Episode Listen Later Nov 15, 2025 5:25


Grab my breakdown of the 5 Low-Cost Businesses That Make $1 Million: https://www.franchiseempire.com/lowcost?utm_source=TJnov152025And if you're interested in franchising but don't know which ones are worth the cost, make sure to check out my 5 Franchises that Make Big Money: https://youtu.be/MPks09QnNcUEver thought about owning a hotel franchise? In this video, I break down one of the most well-known names in hospitality, Hampton by Hilton. From the startup costs to earnings… this one might surprise you. We'll also look at what makes this brand different, and whether it's even realistic for most buyers. If hotel ownership has ever crossed your mind, watch this before making any moves.------------------Considering Investing In A Franchise?

Zero to Profitable Franchise
Is this $200k Donut Shop Worth it? (Dunkin' Costs, Sales, & Fees)

Zero to Profitable Franchise

Play Episode Listen Later Nov 14, 2025 8:51


Thinking about buying a Dunkin' franchise? In this video, we break down everything you need to know from their 2024 FDD. You'll learn how much it actually costs to open a Dunkin' in different formats, what regions perform best, and whether this high-traffic brand still delivers strong margins. If you're considering investing in food or coffee franchises, this breakdown will give you key numbers and questions to think about before moving forward.The video with a Dunkin' franchisee who owned 40+ locations:  https://youtu.be/iIVCfrGpXrs?si=z-PwcLv2eFOzDiuc------------------Considering Investing In A Franchise?

Mining Stock Daily
Coppernico's Ivan Bebek on Expanding Prospective Land at Sombrero

Mining Stock Daily

Play Episode Listen Later Nov 13, 2025 15:02


Coppernico Metals has expanded its concessions through an application covering 2,400 hectares over a newly identified lithocap-epithermal-porphyry target at its Sombrero Project in Peru. Ivan Bebek discusses the strategic acquisition of the land. He also shares some insights into the data collected from the last drill program on the project.

Zero to Profitable Franchise
Most Franchise Buyers Never Ask This (And Regret It Later)

Zero to Profitable Franchise

Play Episode Listen Later Nov 13, 2025 5:36


Grab our breakdown of the 5 Low-Cost Businesses That Make $1 Million: https://www.franchiseempire.com/lowcost?utm_source=FENov132025Buying a franchise is a life investment, but most people never ask the questions that actually protect them. In this episode, we break down the critical questions you must ask a franchisor before signing, how to spot red flags early, and what separates smart franchise buyers from those who regret it later. You'll also learn how to keep your “why” front and center, avoid emotional burnout, and approach the process like a true entrepreneur.------------------Considering Investing In A Franchise?

Nick & Zoe - hit Gippsland
Talking Gippsland- Episode 48 - Willem Duursma Prospective AFL Number 1 Pick 2025

Nick & Zoe - hit Gippsland

Play Episode Listen Later Nov 13, 2025 13:45


In this episode Ed catches up with arguably the standout player of this year's under 18 crop of footballers Willem Duursma. The youngest of the four Duursma siblings has been growing his game since debuting for Gippsland's under-18 side in 2023 and looks likely to be taken number one overall at this years AFL National Draft. Willem also has the charm and swagger to captured the fans imagination on and off the field. Enjoy a laugh and a good yarn with Willem Duursma on Talking Gippsland - Local Voices with Local Stories. See omnystudio.com/listener for privacy information.

Saving Lives: Critical Care w/eddyjoemd
Peripheral Vasopressors, Practically Safe: What a 250-Patient Prospective Cohort Means for Your Unit

Saving Lives: Critical Care w/eddyjoemd

Play Episode Listen Later Nov 12, 2025 7:32


A new prospective multicenter cohort of 250 patients with shock examines the safety and outcomes of peripheral vasopressor administration. Extravasation events were rare and clustered only after several days of infusion, while norepinephrine use and simple physiologic markers correlated with survival. In this episode, I translate the findings into bedside guardrails—which sites and gauges to use, how to monitor, and when to pivot to a central line.The Vasopressor & Inotrope HandbookAmazon: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://amzn.to/47qJZe1⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ (Affiliate Link)My Store: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://eddyjoemd.myshopify.com/products/the-vasopressor-inotrope-handbook⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ (Use "podcast" to save 10%)Citation:Petros A, Melkie A, Kotiso KS, Kebede D, Oljira CF, Assefa Gemechu F, Yusuf H, Abebe S, Ashagre A, Bekele A, Yohannes A, Etesa EK, Bedru M, Gebremariam TH. Peripheral line for vasopressor administration: Prospective multicenter observational cohort study for survival and safety. PLoS One. 2025 Oct 13;20(10):e0333275. doi: 10.1371/journal.pone.0333275. PMID: 41082535; PMCID: PMC12517475.

HEA Insider
What Prospective ADs Need to Know About College Presidents

HEA Insider

Play Episode Listen Later Nov 12, 2025 35:50


I believe aspiring athletic directors need to know more about the role of college presidents and what it means to be a member of the cabinet. I asked Kent State VP & University Secretary Dr. Char Reed to talk to me about her role as the chief of staff to the president. Reed explains why she is heavily involved in athletic director hires and gives some insight into the search that ultimately brought Randale Richmond to Kent State. Get your notebook and pencil ready for this conversation because Dr. Reed gives perspective that every prospective AD needs to hear.Higher Ed Athletics is presented by PILYTIX, an AI tech company for higher education institutions and sports organizations. Increased Donations. Fast, Effective Targeting. Improved Performance. Learn more: ⁠https://pilytix.ai/HEA has partnered with AD Vantage for AD Insights and Coaching Hires. AD Vantage empowers athletic directors with comprehensive staff data, performance analytics, and AI-powered candidate insights to make smarter hiring, compensation, and retention decisions in an era where every dollar counts. Learn more: https://www.athleticdirectorvantage.com

Zero to Profitable Franchise
How Much Can You Make with a $500k Tool Truck? (Costs, Sales, & Fees)

Zero to Profitable Franchise

Play Episode Listen Later Nov 7, 2025 10:45


Ever seen a Snap-On Tools truck and wondered how that business actually works? In this video, we break down the Snap-On Tools franchise model in detail, from its 100-year history and unique mobile store concept to startup costs, in-house financing options, and what franchisees are really earning. You'll learn how Snap-On makes money without traditional royalties, what the startup investment looks like, and the real sales data revealed in their Franchise Disclosure Document (FDD).----------------Considering Investing In A Franchise?

Zero to Profitable Franchise
Would You Pick Up Dog Poop For $200K?

Zero to Profitable Franchise

Play Episode Listen Later Nov 5, 2025 12:03


Grab our breakdown of the 5 Low-Cost Businesses That Make $1 Million: https://www.franchiseempire.com/lowcost?utm_source=nov062025This episode breaks down how we narrow 4,000+ franchise brands down to 4-6 best-fit options for each buyer. It dives into questions buyers should be asking themselves, how to filter by business type, how personal preferences and finances shape the options, and how Franchise Empire coaches candidates through the due diligence funnel, all the way from idea to signature.------------------Considering Investing In A Franchise?

Rightly Divide the Word of Truth
Finding a Prospective Spouse

Rightly Divide the Word of Truth

Play Episode Listen Later Nov 4, 2025 52:27


This is the eighth installment (and final for now) in our devotional study series about the Bible principles for interpersonal relations between men and women -- especially husbands and wives.  This week, we are going to look at a few passages from both Peter (1 Peter 3) and Paul (1 Timothy 4 and Titus 2) that give us the principles that should govern men and women in marriage.  And these are what prospective spouses should be looking for in each other.1 Timothy 4:12 KJVLet no man despise thy youth; but be thou an example of the believers, in word, in conversation, in charity, in spirit, in faith, in purity.Related Podcasts:— God's Perspective on Gender Roles— Male/Female Dynamics, Part 1— Male/Female Dynamics, Part 2— Male/Female Dynamics, Part 3— Male/Female Dynamics, Part 4— Male/Female Dynamics, Part 5— Male/Female Dynamics, Part 6— Male/Female Dynamics, Part 7— The Weaker Vessel— Every Wise WomanRelated Podcasts at TrueWisdom:— A Woman of Action— True Valor— Partners in CrimeText UsSupport the showSend questions or comments to: BibleQuestions@ASBzone.comThe Key Principles of Effective Bible Study is a resource which outlines core concepts shown in the Scriptures that will help you to better understand many Biblical themes and doctrines. We have an extended, 24-part podcast series on these principles, and a condensed, 9-part series called God's Precious Word, that is based on the same resource. We also recommend that you check out the True Wisdom podcast which I co-host with Robert Baker -- a different format for Bible Study. Finally, check out these awesome Bible Maps! We pray that all of these resources will be very helpful to you in your Bible Studies.

Zero to Profitable Franchise
The UPS Store: Is it still a good investment in 2025?

Zero to Profitable Franchise

Play Episode Listen Later Nov 1, 2025 6:57


Grab & understand 14 Franchise Buying Mistakes that could destroy your investment: https://www.franchiseempire.com/14fbm?utm_source=TJnov12025Thinking about investing in a UPS Store franchise? In this video, I break down everything you need to know before making a decision, including startup costs, royalties, real franchisee sales numbers, and why the margins might not be as strong as they seem. I also cover surprising facts about the brand's history and size, so you can decide if this 100+ year-old franchise still makes sense in today's market. If you're serious about buying a franchise, this is the kind of insight you can't afford to skip.------------------Considering Investing In A Franchise?

Zero to Profitable Franchise
Why Some People Should NEVER Own a Franchise

Zero to Profitable Franchise

Play Episode Listen Later Oct 31, 2025 9:06


Grab & understand 14 Franchise Buying Mistakes that could destroy your investment: https://www.franchiseempire.com/14fbm?utm_source=FEoct302025Thinking about buying a franchise? Before you write a check or jump on a discovery call, there's one question that could make or break your success: Can you actually follow the system? In this episode, we break down why some candidates get rejected, how franchisors quietly test you before awarding a territory, and the #1 trait that separates the top-performing franchisees from everyone else. If you think franchising is just plug-and-play… watch this first.

Meaningful People
Why the Frum World Is Becoming Financially Unsustainable

Meaningful People

Play Episode Listen Later Oct 25, 2025 87:04


In this Meaningful People episode, financial advisor Moshe Alpert and community advocate Shmuly Hartstein unpack why many frum “middle‑class” families earning $200–300K still feel underwater—tuition that rivals a salary, yom tov and camp costs, seminary and simcha expectations, and the quiet creep of credit‑card debt. They debate income‑based tuition and communal funding versus personal responsibility, and share practical moves: make a real plan, build a budget, ask for a raise or start a side hustle, prioritize local schools in tzedakah, consider lower‑cost simchas or out‑of‑town living, and protect your family with insurance and a will. A candid, solutions‑oriented conversation about money, values, and making frum life sustainable. Moshe Alpert is a Financial Advisor at Ceremian Financial and author of the book ‘Frum Financial Planning: The Easy-to-Read Money Guide for the Orthodox Jewish Community'. https://a.co/d/hsRZrEe and Ceremian.com    Shmuel Hartstein is the founder of Bsefer Chayim, an organization that promotes signing up for Life Insurance in our community. https://www.bseferchayim.org/  This episode was made possible thanks to our sponsors: ►Blooms Kosher   Bring you the best Kosher products worldwide.   https://bloomskosher.com   ______________________________________ ► Colel Chabad Pushka App - The easiest way to give Tzedaka    https://pushka.cc/meaningful    _______________________________________ ► Dream Raffle Win a brand new and fully furnished $1,200,000 apartment in Yerushalayim!    Use Promo code MPP for $10 off and to receive double tickets!   https://thedreamraffle.com/  _____________________________________ ► Lalechet     We're a team of kosher travel experts, here to carry you off to your dream destination swiftly, safely, and seamlessly in an experience you will forever cherish.    https://www.lalechet.com ___________________________________________ ► Town Appliance - Visit the website or message them on WhatsApp     https://www.townappliance.com     https://bit.ly/Townappliance_whatsapp    ______________________________________ ► Touro   Lander College for Men/Beis Medrash L'Talmud offers a unique blend of rigorous Torah study and strong academics, providing students with both spiritual growth and professional preparation. With devoted rebbeim, supportive faculty, and access to Touro's graduate and professional programs, students can pursue over 20 majors and pre-professional tracks — including medicine, law, business, and technology — while maintaining their Jewish values. Highlights include the Medical Honors Pathway with New York Medical College, personalized support services, and an exceptional record of graduate school acceptances. Prospective students are invited to attend the Open House on November 9 to learn more. Visit http://www.lcm.touro.edu/openhouse    ______________________________________ ►  Ketubah - Free Shipping with Code MPP25! At Ketubah.com, every Kesubah is designed with care, blending timeless beauty with texts that are fully halachic, including RCA and Sephardic versions. Our team collaborates with rabbanim and mesadrei kiddushin to ensure each document is accurate and accepted without question. Choosing Ketubah.com means you arrive at your chuppah with peace of mind, knowing your Kesubah is both beautifully crafted and halachically sound. Use code MPP25 for free shipping! https://ketubah.com/meaningful-minutes/?utm_source=Podcast&utm_medium=Clickthrough&utm_campaign=meaningful-people-podcast ______________________________________ ►  Eishet Chayil Eishet Chayil — The Woman of Valor is a new book by Rabbi Yossi Marcus that brings King Solomon's classic poem to life through the stories of 24 remarkable Jewish women — from Sarah and Miriam to Esther and beyond. Drawing on millennia of Jewish scholarship, especially the teachings of the Lubavitcher Rebbe, the book celebrates women of faith, courage, and wisdom. Each verse is paired with contemporary artwork by Israeli artist Lia Baratz, making the book both educational and inspirational for readers of all ages. Dedicated to the women of Nahal Oz who were killed on October 7, 2023, it stands as a tribute to Jewish women of valor throughout history. Already in its second printing, Eishet Chayil is an ideal gift for Bat Mitzvahs, brides, wives, and mothers. Available at https://www.eishetchayil.com and https://store.kehotonline.com/mobile/ Use code MM20 for 20% off when checking out on Kehot.com.

Zero to Profitable Franchise
How Much To Open a Hotel? (DoubleTree by Hilton Costs, Sales, & Fees)

Zero to Profitable Franchise

Play Episode Listen Later Oct 25, 2025 7:46


Grab our breakdown of the 5 Low-Cost Businesses That Make $1 Million: https://www.franchiseempire.com/lowcost?utm_source=FEoct262025What does it really cost to open a DoubleTree by Hilton hotel? In this breakdown, I reveal the startup costs, franchise fees, and royalties for one of Hilton's most well-known hotel brands and why some investors might want to think twice. You'll learn the true cost to open a 250-room hotel, how much DoubleTree charges in royalties, and why their FDD hides the most important number: how much money franchisees actually make. If you've ever dreamed about owning a hotel or just want to understand how these big-money deals work, don't miss this one.------------------Considering Investing In A Franchise?

Zero to Profitable Franchise
#1 Misconception About Franchises That Will COST You Everything

Zero to Profitable Franchise

Play Episode Listen Later Oct 23, 2025 6:52


Grab our breakdown of the 5 Low-Cost Businesses That Make $1 Million: https://www.franchiseempire.com/lowcost?utm_source=FEoct232025Most people think they can buy a franchise and sit back while the money rolls in. But that mindset is exactly what leads to failure. In this episode, we reveal the biggest misconception about franchise ownership and why it's costing people everything. If you're not willing to work the business, you shouldn't buy one. This short breakdown could save you years of frustration.------------------Considering Investing In A Franchise?

Radically Genuine Podcast
206. EXPLOSIVE ADHD Debate You Need to Hear with Psychiatrist Dr. Ryan Sultan

Radically Genuine Podcast

Play Episode Listen Later Oct 23, 2025 129:44


Dr. Ryan Sultan is a Board Certified Adult and Child Psychiatrist, researcher and Assistant Professor of Clinical Psychiatry at Columbia University Irving Medical Center. He is also in private practice with expertise in the evaluation and treatment of ADHD. One in six American boys is now diagnosed with ADHD. In France, it's one in 200. American children are diagnosed with ADHD at rates 30 times higher than other Western nations. We consume 80% of the world's ADHD stimulants despite being 4% of the population.There's no blood test, no brain scan, no biological evidence this "disorder" actually exists - just subjective checklists and lines of questioning. In this essential episode, Dr. McFillin challenges the validity and reliability of ADHD diagnosis, and what unfolds is a stunning revelation about how 7 million children ended up on amphetamines. References:MTA Study (Multimodal Treatment Study of ADHD):MTA Cooperative Group. (1999). A 14-month randomized clinical trial of treatment strategies for ADHD. Archives of General Psychiatry, 56(12), 1073-1086.Molina, B. S., et al. (2009). MTA at 8 years: Prospective follow-up of children treated for combined-type ADHD. Journal of the American Academy of Child & Adolescent Psychiatry, 48(5), 484-500.Key finding: No difference in outcomes between medicated and non-medicated groups at 3-year and 8-year follow-upsCDC ADHD Statistics:CDC. (2022). Data and Statistics About ADHD. Centers for Disease Control and Prevention.7.1 million US children diagnosed with ADHD (11.4% of all children)15.5% of boys diagnosed vs. 7.5% of girls1 in 6 boys aged 4-17 diagnosed with ADHD3.3 million children aged 3-17 currently on ADHD medicationRacial Disparities in Diagnosis of ADHDDSM-5 Field Trial Reliability:Regier, D. A., et al. (2013). DSM-5 field trials in the United States and Canada. American Journal of Psychiatry, 170(1), 59-70.ADHD kappa reliability: 0.61 (research settings) to 0.35 (clinical practice)Financial Data:ADHD medication market: $19.8 billion (2024, Market Research Reports)10-fold increase in stimulant prescriptions: 1990-2024 (DEA production quotas) Faraone, S.V., Sergeant, J., Gillberg, C., & Biederman, J. (2003). The worldwide prevalence of ADHD: Is it an American condition? World Psychiatry, 2(2), 104-113.Funded by Johnson & Johnson (pharmaceutical company)Co-authored by Joseph Biederman (who later had to admit taking $1.6 million from drug companies without disclosure)What This Article Inadvertently Reveals:The Diagnosis Shopping Game: The article admits that using DSM-IV criteria produces the "highest prevalence rates" compared to other diagnostic systems. Translation: American psychiatry created diagnostic criteria that captures the most kids. This isn't discovering disease - it's widening the net.The 20-Fold Difference They Can't Explain: The article acknowledges a "20-fold greater prevalence of childhood hyperactivity in North America compared with England" in 1970s studies. Their explanation? Different diagnostic practices, not different children. So they're admitting the "disease" depends entirely on who's doing the diagnosing.The Admission Hidden in Plain Sight: The authors state that differences in prevalence "reflect differences in diagnostic practice rather than true differences in behavior." They're literally admitting ADHD prevalence is about diagnostic opinion, not biological reality.Even establishment researchers like Faraone admit that ADHD prevalence varies 20-fold based on diagnostic criteria used, not actual differences in children's behavior. They acknowledge it's diagnostic practice, not disease prevalence, that creates these massive variations. This 2003 paper proves psychiatry has known for decades that ADHD rates are artificially inflated by American diagnostic criteria.The Irony: This paper, trying to prove ADHD is universal, actually proves it's a diagnostic construct that changes based on which manual you use. That's not how real diseases work. Visit Center for Integrated Behavioral HealthDr. Roger McFillin / Radically Genuine WebsiteYouTube @RadicallyGenuineDr. Roger McFillin (@DrMcFillin) / XSubstack | Radically Genuine | Dr. Roger McFillinInstagram @radicallygenuineContact Radically GenuineConscious Clinician CollectivePLEASE SUPPORT OUR PARTNERS15% Off Pure Spectrum CBD (Code: RadicallyGenuine)10% off Lovetuner click here

Zero to Profitable Franchise
Is this $500k Tool Truck A Good Investment?

Zero to Profitable Franchise

Play Episode Listen Later Oct 19, 2025 10:45


Grab our breakdown of the 5 Low-Cost Businesses That Make $1 Million: https://www.franchiseempire.com/lowcost?utm_source=FEoct192025In this episode, I break down the Snap-on Tools franchise, one of the most overlooked mobile businesses in America. I cover how the business model works, what it costs to start, how franchisees make money without traditional royalties, and what the real sales numbers reveal. If you've ever wondered whether a Snap-on truck is a smart investment, this deep dive lays out the full picture.------------------Considering Investing In A Franchise?

The KE Report
Cosa Resources – Identification Of Prospective Drill-Ready Targets at the Darby Uranium Project In The Athabasca Basin For 2026 Exploration Program

The KE Report

Play Episode Listen Later Oct 19, 2025 14:26


Keith Bodnarchuk, President and CEO, and Andy Carmichael, VP of Exploration of Cosa Resources Corp. (TSXV: COSA) (OTCQB: COSAF) (FSE: SSKU), both join me to review the news released on October 14th which announced the identification of multiple high priority follow up drill targets at the Darby Project.  Darby is a joint venture (JV) between Cosa and Denison Mines Corp. (TSX: DML) (NYSE American: DNN) and is located 10 kilometres west of Cameco's Cigar Lake Mine in the eastern Athabasca Basin, Saskatchewan. Cosa is the project operator and holds a 70% interest with Denison holding a 30% interest.   Keith starts us up highlighting the prospective geology and historic work that made the Darby Project a vital component of the JV transaction with Denison. The recent identification of new drill targets as a results further analysis from the exploration team supports Cosa's thesis that Darby is a mature, discovery-ready project that will receive drilling in the year to come.   The identification of highly prospective drill ready targets came as a result of extensive historical drill core and data review at the Delta and Charlie trends by Cosa's Chairman Steve Blower and VP Exploration Andy Carmichael, as they relogged all historical Darby drill holes in June of this year. Their work confirmed desktop interpretations and generated immediate follow up targets.   When the team at Cosa reviewed the historic work by prior operators, it interpreted that of 31 drill holes on the Property targeting conductive anomalies only 13 (42%) explained their target and only six (19%) were effective evaluations of the targeted area, leaving over 80% of the Projects' 40 kilometres of conductive strike length untested. Multiple historical drill holes intersected features suggesting proximity to uranium mineralization – warranting direct follow-up drilling in the future.   Andy mentioned that with a more experienced scientific understanding and framework today, and by applying the same target identification approach that led them to discover the Hurricane Deposit in 2018, that they are very encouraged by the historical data and drill core. Coincident alteration, illite, and chlorite plus broad zones of anomalous uranium in the lower sandstone are strong indicators of a uranium bearing system in the eastern Athabasca including at the nearby Cigar Lake mine.   The Company will begin the approaching 2026 drilling season with highly prospective follow up targets at both Darby and Murphy Lake North. Keith mentioned that they are looking forward to finalizing drilling plans and budgets their joint venture partner and largest shareholder, Denison Mines, and discussed the benefit of their continued guidance and support on these exploration initiatives.     If you have any questions for Keith or Andy regarding Cosa Resources, then please email them to me at Shad@kereport.com.     Click here to follow the most recent news from Cosa Resources   For more market commentary & interview summaries, subscribe to our Substacks: https://kereport.substack.com/ https://excelsiorprosperity.substack.com/   Investment disclaimer: This content is for informational and educational purposes only and does not constitute investment advice, an offer, or a solicitation to buy or sell any security. Investing in equities and commodities involves risk, including the possible loss of principal. Do your own research and consult a licensed financial advisor before making any investment decisions. Guests and hosts may own shares in companies mentioned.

Meaningful People
The Shidduch System May Be Broken. Adina Reich Has a Solution.

Meaningful People

Play Episode Listen Later Oct 18, 2025 70:43


In this heartfelt and eye-opening conversation, veteran shadchan Adina Reich traces the evolution of the shidduch system — from handwritten index cards to WhatsApp chats — and reflects on the hopes, heartbreak, and faith that define it. She opens up about the challenges singles and parents face, the emotional toll on shadchanim, and her groundbreaking new initiative, The Shidduch Lounge, designed to bring back organic, Torah-centered connections. With humor, honesty, and compassion, Adina offers both an insider's view of the shidduch world and a vision for how it can heal. This episode was made possible thanks to our sponsors: ►Blooms Kosher   Bring you the best Kosher products worldwide.   https://bloomskosher.com   ______________________________________ ► Colel Chabad Pushka App - The easiest way to give Tzedaka    https://pushka.cc/meaningful    _______________________________________ ► Dream Raffle Win a brand new and fully furnished $1,200,000 apartment in Yerushalayim!    Use Promo code MPP for $10 off and to receive double tickets!   https://thedreamraffle.com/  _____________________________________ ► Lalechet     We're a team of kosher travel experts, here to carry you off to your dream destination swiftly, safely, and seamlessly in an experience you will forever cherish.    https://www.lalechet.com ___________________________________________ ► Town Appliance - Visit the website or message them on WhatsApp     https://www.townappliance.com     https://bit.ly/Townappliance_whatsapp    ______________________________________ ► Touro   Lander College for Men/Beis Medrash L'Talmud offers a unique blend of rigorous Torah study and strong academics, providing students with both spiritual growth and professional preparation. With devoted rebbeim, supportive faculty, and access to Touro's graduate and professional programs, students can pursue over 20 majors and pre-professional tracks — including medicine, law, business, and technology — while maintaining their Jewish values. Highlights include the Medical Honors Pathway with New York Medical College, personalized support services, and an exceptional record of graduate school acceptances. Prospective students are invited to attend the Open House on November 9 to learn more. Visit http://www.lcm.touro.edu/openhouse    ______________________________________ ►  Ketubah At Ketubah.com, every Kesubah is designed with care, blending timeless beauty with texts that are fully halachic, including RCA and Sephardic versions. Our team collaborates with rabbanim and mesadrei kiddushin to ensure each document is accurate and accepted without question. Choosing Ketubah.com means you arrive at your chuppah with peace of mind, knowing your Kesubah is both beautifully crafted and halachically sound. https://ketubah.com/meaningful-minutes/?utm_source=Podcast&utm_medium=Clickthrough&utm_campaign=meaningful-people-podcast ______________________________________ ►  Eishet Chayil Eishet Chayil — The Woman of Valor is a new book by Rabbi Yossi Marcus that brings King Solomon's classic poem to life through the stories of 24 remarkable Jewish women — from Sarah and Miriam to Esther and beyond. Drawing on millennia of Jewish scholarship, especially the teachings of the Lubavitcher Rebbe, the book celebrates women of faith, courage, and wisdom. Each verse is paired with contemporary artwork by Israeli artist Lia Baratz, making the book both educational and inspirational for readers of all ages. Dedicated to the women of Nahal Oz who were killed on October 7, 2023, it stands as a tribute to Jewish women of valor throughout history. Already in its second printing, Eishet Chayil is an ideal gift for Bat Mitzvahs, brides, wives, and mothers. Available at https://www.eishetchayil.com and https://store.kehotonline.com/mobile/ Use code MM20 for 20% off when checking out on Kehot.com.  

Zero to Profitable Franchise
$1M Business Ideas For 2025 (TRUTH)

Zero to Profitable Franchise

Play Episode Listen Later Oct 17, 2025 20:55


Grab our breakdown of the 5 Low-Cost Businesses That Make $1 Million: https://www.franchiseempire.com/lowcost?utm_source=tjoct042025Think a business needs to be sexy to make you rich? Think again. In this video, I react to a list of 6 businesses they claim consistently create millionaires and explain if they are truly a good investment in this economy. Watch to find out my insight on which boring model could be your shortcut to long-term wealth.

Zero to Profitable Franchise
When You Should Quit Your Job To Start A Business

Zero to Profitable Franchise

Play Episode Listen Later Oct 16, 2025 8:24


If you want to learn more franchise advice join The #1 Community for Owning a Money-Making Franchise: https://www.skool.com/franchiseempirebuilders/aboutMost people dream of quitting their job to start a business. But few ever know when the timing is actually right, and even fewer are truly ready for what comes next. In this episode of the Zero to Profitable Franchise Podcast, Tariq Johnson breaks down what separates people who say they want freedom… from those who actually achieve it. If you've ever thought, “Should I quit my job?” this conversation could be the wake-up call (or the green light) you need.------------------Considering Investing In A Franchise?

The OJSM Hot Corner
“Interportal Capsulotomy Closure Does Not Improve the Results After Hip Arthroscopy at 1-Year Follow-up: A Prospective Randomized Controlled Study” with Author Dr. Bjarne Mygind-Klavsen, MD

The OJSM Hot Corner

Play Episode Listen Later Oct 16, 2025 18:43


Whether to close the capsule at the conclusion of hip arthroscopy remains a matter of great debate.  Prior data has been mixed. Dr. Bjarne Mygind-Klavsen from Aarhus University Hospital in Denmark joints us to discuss the results of his team's randomized controlled study comparing interportal capsulotomy closure versus no closure at 1 year following hip arthroscopy.

Blood Cancer Talks
Episode 66. International Myeloma Society 2025 Annual Meeting Updates with Dr. Alfred Garfall: The Bispecific Bonanza

Blood Cancer Talks

Play Episode Listen Later Oct 15, 2025 52:16


This episode provides comprehensive coverage of key clinical trial updates from the 2025 International Myeloma Society (IMS) Annual Meeting in Toronto, with special focus on bispecific antibodies and novel immunotherapies across the multiple myeloma disease continuum—from smoldering disease through relapsed/refractory settings. Dr. Alfred Garfall provides expert commentary on study design, efficacy, safety considerations, and clinical implications.Topics Covered1. SMOLDERING MULTIPLE MYELOMALINKER-SMM1Phase 2, open-label study of linvoseltamab monotherapy (200 mg) in patients with high-risk smoldering multiple myeloma by 20/2/20 or PETHEMA criteria, with 2-year treatment duration.Discussion Points:Appropriateness of 2-year treatment duration for precursor conditionEfficacy and MRD-negative ratesSafety considerations in asymptomatic populationPatient selection if available today2. NEWLY DIAGNOSED MULTIPLE MYELOMAMajesTEC-5Phase 2 trial evaluating three teclistamab-daratumumab-based induction regimens in 49 transplant-eligible NDMM patients, followed by auto-transplant and fixed-duration Tec-Dara maintenance.Discussion Points:Post-induction MRD-negativity rates with Tec-DR and Tec-DVRGrade 3-5 infection rates and infection-related deathsQuestionable utility of bortezomib and need for ASCT with 100% MRD-negativityHigh infection prophylaxis requirementsMagnetisMM-6Phase 1/2 dose-finding study of fixed-dose elranatamab 76 mg Q4W with Dara-Len in 37 transplant-ineligible NDMM patients (median age 75 years).Discussion Points:VGPR or better ratesSafety profile including infections and CRS/ICANSRisk of continuous therapy in elderly/frail populationLINKER-MM4Phase 1/2 study of linvoseltamab monotherapy in NDMM with both transplant-eligible and transplant-ineligible pathways, exploring three dose levels (50, 100, 200 mg).Discussion Points:Efficacy of single-agent Linvo in NDMMWhether any NDMM population could achieve long-term control with single-agent BCMA BsAbSafety profile3. RELAPSED/REFRACTORY MULTIPLE MYELOMACAMMA-1Phase 1b randomized dose-expansion study of cevostamab (FcRH5×CD3 bispecific) combined with pomalidomide-dexamethasone in BCMA-naïve patients with median 2 prior lines of therapy.Discussion Points:Efficacy and safety resultsPositioning in treatment paradigmUse before BCMA BsAbs?Sonrotoclax + Dexamethasone in t(11;14) R/R MMPhase 1/2 study of sonrotoclax (next-generation BCL2 inhibitor) plus dexamethasone as an all-oral regimen in patients with t(11;14) R/R MM (median 3 prior lines, ~75% triple-exposed).Discussion Points:Efficacy including response rate and PFSSafety profileFuture of BCL2 inhibitors in t(11;14) myeloma in the era of BsAbs and CAR TRedirecTT-1Phase 2 trial combining teclistamab + talquetamab in 90 heavily pretreated patients with R/R extraosseous extramedullary disease (84% triple-class refractory, 36% penta-refractory, 20% prior BCMA CAR T).Discussion Points:Response rate and durability in difficult-to-treat populationSafety concerns with dual bispecific combinationOff-label use considerations4. CAR T-CELL THERAPY TOXICITIESCAR T Immune-Related Adverse Events (UPenn Study - Ho et al)Large cohort study of 198 patients (125 cilta-cel, 73 ide-cel) examining all adverse events other than CRS, ICANS, IEC-HS, and IECAHT.Discussion Points:Landscape of CAR T IRAEs: incidence, types, and timingRisk factors identified for CirAEsMechanism of toxicities and role of CD4+ CAR T-cellsClinical implications: Should prophylactic corticosteroids be used? What ALC threshold? Optimal dose/duration? Prospective studies needed?

Zero to Profitable Franchise
How Much Money Does a Smoothie King Franchise Really Make? (Costs, Sales, & Fees)

Zero to Profitable Franchise

Play Episode Listen Later Oct 11, 2025 7:02


Is the Smoothie King franchise really worth the $1.2 million investment? In this video, I break down everything you need to know from startup costs and royalty fees to average sales and profit margins. We dig into Smoothie King's 2025 FDD to uncover what franchise owners are actually making and whether this is a smart play or a costly mistake.------------------Considering Investing In A Franchise?

Zero to Profitable Franchise
Buy A Business That Already makes $100,000?!

Zero to Profitable Franchise

Play Episode Listen Later Oct 9, 2025 7:50


Most people think buying a business means instant income and freedom, but that's rarely how it works. In this episode, we break down the misconceptions around franchise resales and why they often lead to frustration. You'll learn the difference between starting fresh vs. buying an existing business. We also unpack the fear of starting from zero and why that mindset might be holding you back. This episode will help you think more clearly about your next move.------------------Considering Investing In A Franchise?

YOU The Owners Manual Radio Show
EP 1,252B - Recent Study on Ultra Processed Foods (UPFs)

YOU The Owners Manual Radio Show

Play Episode Listen Later Oct 7, 2025


Jacob Teitelbaum, M.D., is one of the most frequently quoted post viral CFS, fibromyalgia, energy, sleep and pain medical authorities in the world. He is here today to discuss the findings of a recent study on ultra processed foods. Ultra processed foods are becoming dominant in the global food supply. Prospective cohort studies have consistently found an association between high consumption of ultra processed foods and increased risk of several noncommunicable diseases and all-cause mortality. The study aimed to (1) estimate the risk of all-cause mortality for ultra processed foods consumption and (2) estimate the attributable epidemiologic burden of ultra processed food consumption in 8 select countries.

Zero to Profitable Franchise
Why Everyone Is Choosing Franchising (It's Not What You Think)

Zero to Profitable Franchise

Play Episode Listen Later Oct 1, 2025 5:16


Starting a business from scratch sounds exciting until you're buried in building systems, hiring teams, and guessing what works. In this video, I break down why so many entrepreneurs are turning to franchising instead and why it's not just about royalties or brand names. You'll discover the hidden risks of going it alone, the real advantages of a proven system, and how franchising can help you start faster, scale smarter, and avoid costly mistakes. If you're deciding between building your own business or buying a franchise, this episode could save you years of trial and error.------------------Considering Investing In A Franchise?

Behind The Knife: The Surgery Podcast
Clinical Challenges in Trauma Surgery: Stabbed in the Back - Decision Making in a Penetrating Junctional Vascular Injury

Behind The Knife: The Surgery Podcast

Play Episode Listen Later Sep 29, 2025 33:53


“It's 5pm and your Consultant (attending) has headed off home. A patient arrives in the resuscitation room blood spurting from a stab wound in the armpit. Join Roisin – a junior Major Trauma fellow, Prash – a surgical trainee, Max – a senior trauma surgery fellow, and Chris – a Consultant trauma surgeon, as we talk through decision making from point of injury to aftercare in this challenging trauma surgical case”. • Hosts: Bulleted list of host names, including title, institution, & social media handles if indicated 1.     Mr Prashanth Ramaraj. General Surgery trainee, Edinburgh rotation. @LonTraumaSchool 2.     Dr Roisin Kelly. Major Trauma Junior Clinical Fellow, Royal London Hospital.  3.     Mr Max Marsden. Resuscitative Major Trauma Fellow, Royal London Hospital. @maxmarsden83 4.     Mr Christopher Aylwin. Consultant Trauma & Vascular Surgeon and Co-Programme Director MSc Trauma Sciences at Queen Mary University of London. @cjaylwin • Learning objectives: Bulleted list of learning objectives. A)    To become familiar with prehospital methods of haemorrhage control in penetrating junctional injuries. B)     To recognise the benefits of prehospital blood product resuscitation in some trauma patients. C)     To follow the nuanced decision making in decision for CT scan in a patient with a penetrating junctional injury. D)    To describe the possible approaches to the axillary artery in the context of resuscitative trauma surgery. E)     To become familiar with decision making around intraoperative systemic anticoagulation in the trauma patient. F)     To become familiar with decision making on type of repair and graft material in vascular trauma. G)    To recognise the team approach in holistic trauma care through the continuum of trauma care. • References: Bulleted list of references with PubMed links. 1.    Perkins Z. et al., 2012. Epidemiology and Outcome of Vascular Trauma at a British Major Trauma Centre. EJVES. https://www.ejves.com/article/S1078-5884(12)00337-1/fulltext 2.    Ramaraj P., et al. 2025. The anatomical distribution of penetrating junctional injuries and their resource implications: A retrospective cohort study. Injury. https://www.injuryjournal.com/article/S0020-1383(24)00771-X/ 3.    Smith, S., et al. 2019. The effectiveness of junctional tourniquets: A systematic review and meta-analysis. J Trauma Acute Care Surg. https://journals.lww.com/jtrauma/abstract/2019/03000/the_effectiveness_of_junctional_tourniquets__a.20.aspx 4.    Rijnhout TWH, et al. 2019. Is prehospital blood transfusion effective and safe in haemorrhagic trauma patients? A systematic review and meta-analysis. Injury. https://www.injuryjournal.com/article/S0020-1383(19)30133-0/ 5.    Davenport R, et al. 2023. Prehospital blood transfusion: Can we agree on a standardised approach? Injury. https://www.injuryjournal.com/article/S0020-1383(22)00915-9. 6.    Borgman MA., et al. 2007. The Ratio of Blood Products Transfused Affects Mortality in Patients Receiving Massive Transfusions at a Combat Support Hospital. J Trauma Acute Care Surg. https://journals.lww.com/jtrauma/fulltext/2007/10000/the_ratio_of_blood_products_transfused_affects.13.aspx 7.    Holcomb JB., et al. 2013. The Prospective, Observational, Multicenter, Major Trauma Transfusion (PROMMTT) Study. Comparative Effectiveness of a Time-Varying Treatment With Competing Risks. JAMA Surgery. https://jamanetwork.com/journals/jamasurgery/fullarticle/1379768 8.    Holcomb JB, et al. 2015. Transfusion of Plasma, Platelets, and Red Blood Cells in a 1:1:1 vs a 1:1:2 Ratio and Mortality in Patients With Severe Trauma. The PROPPR Randomized Clinical Trial. JAMA. https://jamanetwork.com/journals/jama/fullarticle/2107789 9.    Davenport R., et al. 2023. Early and Empirical High-Dose Cryoprecipitate for Hemorrhage After Traumatic Injury. The CRYOSTAT-2 Randomized Clinical Trial. JAMA. https://jamanetwork.com/journals/jama/fullarticle/2810756 10.   Baksaas-Aasen K., et al. 2020. Viscoelastic haemostatic assay augmented protocols for major trauma haemorrhage (ITACTIC): a randomized, controlled trial. ICM. https://link.springer.com/article/10.1007/s00134-020-06266-1 11. Wahlgren CM., et al. 2025. European Society for Vascular Surgery (ESVS) 2025 Clinical Practice Guidelines on the Management of Vascular Trauma. EJVES. https://esvs.org/wp-content/uploads/2025/01/2025-Vascular-Trauma-Guidelines.pdf 12. Khan S., et al. 2020. A meta-analysis on anticoagulation after vascular trauma. Eur J Traum Emerg Surg. https://link.springer.com/article/10.1007/s00068-020-01321-4 13. Stonko DP., et al. 2022. Postoperative antiplatelet and/or anticoagulation use does not impact complication or reintervention rates after vein repair of arterial injury: A PROOVIT study. Vascular. https://journals.sagepub.com/doi/10.1177/17085381221082371?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.   If you liked this episode, check out our recent episodes here: https://behindtheknife.org/listen Behind the Knife Premium: General Surgery Oral Board Review Course: https://behindtheknife.org/premium/general-surgery-oral-board-review Trauma Surgery Video Atlas: https://behindtheknife.org/premium/trauma-surgery-video-atlas Dominate Surgery: A High-Yield Guide to Your Surgery Clerkship: https://behindtheknife.org/premium/dominate-surgery-a-high-yield-guide-to-your-surgery-clerkship Dominate Surgery for APPs: A High-Yield Guide to Your Surgery Rotation: https://behindtheknife.org/premium/dominate-surgery-for-apps-a-high-yield-guide-to-your-surgery-rotation Vascular Surgery Oral Board Review Course: https://behindtheknife.org/premium/vascular-surgery-oral-board-audio-review Colorectal Surgery Oral Board Review Course: https://behindtheknife.org/premium/colorectal-surgery-oral-board-audio-review Surgical Oncology Oral Board Review Course: https://behindtheknife.org/premium/surgical-oncology-oral-board-audio-review Cardiothoracic Oral Board Review Course: https://behindtheknife.org/premium/cardiothoracic-surgery-oral-board-audio-review Download our App: Apple App Store: https://apps.apple.com/us/app/behind-the-knife/id1672420049 Android/Google Play: https://play.google.com/store/apps/details?id=com.btk.app&hl=en_US

Zero to Profitable Franchise
Should YOU Buy a Franchise? (The Honest Truth)

Zero to Profitable Franchise

Play Episode Listen Later Sep 28, 2025 4:48


Grab our breakdown of the 5 Low-Cost Businesses That Make $1 Million: https://www.franchiseempire.com/lowcost?utm_source=FEsep282025Starting a business from scratch sounds exciting until you realize how much you have to figure out on your own. In this episode, we break down the real differences between launching a startup and buying into a franchise. From building a team to finding vendors and creating your first marketing plan, we expose the time-consuming grind most new entrepreneurs face. Compare that with a franchise, where the systems are already in place and your job is to execute. ------------------Considering Investing In A Franchise?

Zero to Profitable Franchise
Is Investing in Tropical Smoothie Worth It?! (Costs, Sales, & Fees)

Zero to Profitable Franchise

Play Episode Listen Later Sep 25, 2025 9:19


Grab our breakdown of the 5 Low-Cost Businesses That Make $1 Million: https://www.franchiseempire.com/lowcost?utm_source=FEsep252025Curious about Tropical Smoothie franchise numbers in 2025?In this breakdown, I walk through their most recent Franchise Disclosure Document (FDD), covering real startup costs, royalties, average sales, and margins. With over 1,500 locations and top performers making up to $2.6 million, is Tropical Smoothie a good franchise to buy? Learn what it really takes to own one of the most talked-about smoothie franchises.------------------Considering Investing In A Franchise?

Blood Cancer Talks
Episode 65. Circulating Tumor DNA in DLBCL with Dr. Ash Alizadeh and Dr. David Russler-Germain

Blood Cancer Talks

Play Episode Listen Later Sep 24, 2025 53:08


In this episode of Blood Cancer Talks, hosts Eddie, Ashwin, and Raj welcome two distinguished experts to explore the cutting-edge field of circulating tumor DNA (ctDNA) in B-cell lymphomas. Dr. David Russler-Germain, a lymphoma clinician from Siteman Cancer Centre at Washington University in St. Louis, returns as a familiar voice to the podcast audience. Joining him is Dr. Ash Alizadeh, the Moghadam Family Professor of Medicine, Oncology, and Hematology at Stanford University and leader of the Cancer Genomics Program at Stanford Cancer Institute. Dr. Alizadeh has been instrumental in advancing our understanding of lymphomagenesis and lymphoma genetics over the past two decades, pioneering multiple ctDNA techniques that are revolutionizing cancer care. Together, they discuss the transformative potential of ctDNA technology in B-cell lymphomas, particularly DLBCL, covering everything from the technical evolution of biomarker detection to groundbreaking clinical data that may reshape how we monitor and treat these aggressive cancers. Key Discussion Topics1. Genetic Heterogeneity in B-Cell LymphomasComplex genetic landscape of DLBCLImplications for treatment strategiesNeed for personalized approaches 2. Clinical Need for ctDNA in LymphomaWhy ctDNA is needed in aggressive lymphomas:Curative vs. non-curative treatment settingsLimitations of current PET imagingAdditional prognostic information beyond imagingRisk stratification capabilitiesPotential to avoid overtreatmentTherapy adaptation opportunities 3. Challenges in Lymphoma MRD AssessmentWhy lymphoma MRD is more complex than other hematologic malignancies:Differences from acute leukemias, CLL, and myelomaTechnical challenges specific to lymphoid tumorsLower circulating tumor burden compared to liquid tumors 4. ClonoSEQ TechnologyMechanism: Immunoglobulin sequencing approachAdvantages: Established platform with regulatory approvalDisadvantages: Limited sensitivity in peripheral blood, requires adequate tumor sample 5. CAPP-Seq TechnologyFull Name: Cancer Personalized Profiling by Deep SequencingInnovation: Developed ~10 years ago by Dr. Alizadeh's groupMechanism: Targeted sequencing of cancer-specific mutationsAdvantages: High sensitivity, personalized approach 6. PhasED-Seq TechnologyEvolution: Next-generation advancement of CAPP-SeqKey Improvements: Enhanced sensitivity and specificityTechnical Advances: Phased variant detection Clinical Data Highlights1. Remission Assessment by ctDNA in LBCL on 5 prospective studies of frontline anthracycline-based chemo-immunotherapy: https://pubmed.ncbi.nlm.nih.gov/40802906/2. Prospective validation of end of treatment ctDNA-MRD by PhasED-Seq in DLBCL patients from HOVON-902 clinical trial: https://ascopubs.org/doi/10.1200/JCO.2025.43.16_suppl.70003. Korean data on prognostic utility of ctDNA: https://ashpublications.org/blood/article/142/Supplement%201/69/501573 

Zero to Profitable Franchise
Papa John's Franchise: Is $850K Worth It?

Zero to Profitable Franchise

Play Episode Listen Later Sep 21, 2025 8:34


Download our list of 42 High Performing (and profitable) Franchises: https://www.franchiseempire.com/42hpfThinking about buying a Papa John's franchise? In this breakdown, I walk through the real startup costs, profit potential, and whether this $850,000 pizza franchise is actually a good deal. We cover how much Papa John's franchise owners make, franchise fees, royalties, and everything else you need to know straight from the 2025 FDD.------------------Considering Investing In A Franchise?

Menlo.Church - Sermon Audio
Meet our Prospective Elders! | Menlo Midweek | Janie Sacks, Kevin Peterson, Maddie Van Gorp

Menlo.Church - Sermon Audio

Play Episode Listen Later Sep 12, 2025 34:14


On Sept 21, Covenant Partners will be able to vote in our new prospective elders! Janie has her roots at Mountain View, San Jose and most recently our Saratoga Campus. Kevin serves as a kids volunteer at our San Mateo Campus and is part of our search committee for our next permanent location for his campus. Maddie also serves with kids at our Menlo Park Campus. Find out more information around our Annual Congregation Meeting happening in services on the 9/21.