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Mass protests are erupting in Britain, Germany, and the Netherlands over unchecked migration and crime. Leaders like German Chancellor Friedrich Merz admit that their welfare states can no longer sustain massive entitlement spending for migrants who entered illegally. Victor Davis Hanson lays out why Europe's future hangs in the balance and what steps it must take to restore stability, security, and common sense on today's episode of “Victor Davis Hanson: In His Own Words.” “The whole socialist paradigm is not producing goods and service that allow such general entitlements. The borders are insecure. Illegal immigrants are not assimilated, acculturated, integrated into the German, French, European body politic. And they're gonna have a terrible time spending 5% of GDP to defend themselves. This is in addition to having to lower their $200 billion surplus with the United States. “We know what Europe has to do. It has to return to commonsense energy policies; use their natural gas, use oil, to the extent they have it; build nuclear plants; be competitive on the world market, in terms of energy cost. They need to secure their borders. They need to have legal-only immigration. They need to prune back the state, the socialist state. Can they do it?”
LinksEStack: https://estack.reponestrength.com/RepOne Website: https://www.reponestrength.com/Jordan's LI Post: http://bit.ly/3JBWZp4Chapters00:00 Introduction to Jordan Burke and Rep One Strength02:18 The Journey of Open Barbell and Velocity-Based Training05:11 Transition from Engineering to Powerlifting Coaching07:47 The Birth of Squats in Science10:00 Understanding Velocity-Based Training10:20 Evolution from Open Barbell to Rep One Strength13:56 Current Products and Future Directions of Rep One Strength17:41 The Concept and Development of eStack22:20 The Vision Behind eStack27:25 Integration and Compatibility with Existing Equipment31:21 Comparing eStack with Competitors37:04 User Experience and Automation in Training41:24 Feedback from Early Adopters and Market Response44:59 Future of Digital Weight Technology57:39 Certification, Pricing, and Market Strategy
The wait is over. In this follow-up to our origin story, we're officially pulling the curtain all the way back and unveiling what Project B has been all along: The Fitness League — a fitness platform built for busy humans who want to train smarter, live stronger, and actually enjoy the process. In this episode, we share how this project came to life after walking away from Fit Coach Pro, and why The Fitness League isn't just an app — it's a movement. A community. A new standard. We're talking: The full vision behind The Fitness League How we're using tech to make fitness personal (and fun) Why we believe gamifying health can change how people show up The core values driving everything we build What to expect as a member of the League If you've ever felt like fitness apps were built for someone else's life — this one's for you. We didn't just build another app. We built what we wished existed. And it will soon be yours too. APPLY FOR COACHING: https://www.lvltncoaching.com/1-1-coaching SDE Method app: https://www.lvltncoaching.com/sde-method-app The Fitness League Waiting List https://quest.lvltncoaching.com/project-b Macros Guide https://www.lvltncoaching.com/free-resources/calculate-your-macros Join the Facebook Community: https://www.facebook.com/groups/lvltncoaching FREE TOOLS to start your health and fitness journey: https://www.lvltncoaching.com/resources/freebies Alessandra's Instagram: http://instagram.com/alessandrascutnik Joelle's Instagram: https://www.instagram.com/joellesamantha?igsh=ZnVhZjFjczN0OTdn Josh's Instagram: http://instagram.com/joshscutnik Chapters 00:00 The Birth of the Fitness League 05:47 Transitioning from Fit Coach Pro to a New Vision 10:34 The Evolution of Project B 14:44 Building a Community and Engaging Users 19:26 The Importance of Detail and Team Dynamics 24:07 The Vision for a Happier, Healthier World 28:47 Core Values and Future Directions 33:14 Features and Accessibility of the Fitness League 40:29 Enhancing Fitness Through Technology 42:56 Gamification and User Engagement in Fitness 46:35 Challenges: Building Community and Healthy Habits 50:48 The Vision for Future Community Events 56:28 The Journey of Building the Fitness League
Send us a textTake a seat in the Batcave as Shannon pulls back the curtain on five years of podcasting journey and the evolving shed industry landscape of 2025. This rare monologue episode offers an intimate look at where Shed Geek started, where it's heading, and the philosophy driving its growth.Shannon extends a heartfelt invitation to everyone in the shed world—dealers, manufacturers, haulers, and service providers—to share their unique stories on the podcast. "Everyone is welcome, even if we compete," he emphasizes, believing that transparent conversations benefit the entire industry. The podcast has become more than just interviews; it's a digital magazine where shed professionals can showcase their expertise while helping others grow.The conversation explores exciting developments across multiple business fronts. From the new office space (converted from an old church) to the evolution of Shed Geek Marketing's approach that prioritizes education over sales tactics, Shannon reveals how their client-focused philosophy has fueled 187% growth. He also dives into the RTO business transformation, ShedHub's powerful SEO potential, and upcoming industry events that signal a maturing, more organized shed community.Throughout the episode runs a thread of genuine gratitude—to listeners, advertisers, family members, and ultimately to finding purpose through serving the shed industry. Shannon's perspective on marketing as an investment rather than an expense offers valuable insight for any business owner looking to grow strategically.Whether you're a shed industry veteran or newcomer, this candid conversation offers both practical business wisdom and a reminder of the community-building power of shared knowledge. Ready to share your story or learn more about the services discussed? Reach out to info@shedgeek.com and become part of the ongoing conversation.For more information or to know more about the Shed Geek Podcast visit us at our website.Would you like to receive our weekly newsletter? Sign up here.Follow us on Twitter, Instagram, Facebook, or YouTube at the handle @shedgeekpodcast.To be a guest on the Shed Geek Podcast visit our website and fill out the "Contact Us" form.To suggest show topics or ask questions you want answered email us at info@shedgeek.com.This episodes Sponsors:Studio Sponsor: Shed ProNewfound SolutionsShed ChallengerCALShed SuiteLuxGuard
Drs. Sophia O'Brien Austin Pantel, explore the role of 18F-Fluoroestradiol (FES) PET-CT in the diagnosis and management of ER-positive breast cancer. They review key findings from their RadioGraphics article, discuss updates to national guidelines, and highlight how FES imaging improves patient care by assessing estrogen receptor expression across all sites of disease. 18F-Fluoroestradiol: Current Applications and Future Directions. O'Brien et al. RadioGraphics 2023; 43(3):e220143
In this episode of The Future of Teamwork, Dane Groeneveld interviews Nogol Madani, Founder & CEO of Glee Factor, to talk about how to future-proof teams for the age of AI.Dane and Nogol go deep into the concept of psychological safety – what it really means, why it's misunderstood, and how it can make or break collaboration, innovation, and trust. Nogol shares why leaders must design low-stakes moments for their teams to take risks, why unlearning is just as important as learning, and how small, consistent actions can build a cultural infrastructure that supports innovation.This conversation is a reminder that the future of teamwork isn't just about technology – it's about people, trust, and building workplaces where everyone feels safe to contribute their best ideas.
In an August 14th Vogue Business article by Madeleine Schultz , Saks Global, the parent company of Saks Fifth Avenue, Neiman Marcus and Bergdorf Goodman, discussed its personalisation strategy and an investment of $600 million for it's new platform. The only problem is: based on the article, we think they got it wrong. In this episode of the Experience Strategy Podcast, hosts Aransas Savas, Joe Pine, and Dave Norton delve into the evolving landscape of personalization in retail, particularly focusing on Saks Global's new strategies. They discuss the importance of understanding customer modes, the role of contextual data, and the challenges faced by traditional personalization approaches. The conversation highlights the need for brands to meet customers where they are, especially in the age of social shopping, and emphasizes the integration of online and offline experiences to enhance customer engagement. This episode is brought to you by The Cargo Agency and Feedback Now. Takeaways Personalization is a form of customization for individuals. Saks has invested heavily in personalization strategies. Modes thinking is crucial for effective personalization. Contextual data is essential for understanding customer needs. Traditional personalization approaches may feel outdated. Social shopping is a growing trend in retail. Brands must meet customers where they are online. Integration of online and offline experiences is key. Personalization should not just be about demographics. The future of retail lies in innovative and brave strategies. Chapters 00:00 Introduction to Personalization in Retail 02:57 Exploring Hyper-Personalization Strategies 05:55 The Importance of Context in Personalization 09:05 The Role of AI and Machine Learning 11:57 Challenges of Traditional Retail Personalization 14:49 The Shift Towards Social Shopping 17:45 Integrating Online and Offline Experiences 20:48 Future Directions for Retail Personalization Read more https://www.voguebusiness.com/story/consumers/inside-saks-globals-personalisation-strategy?utm_source=chatgpt.com Podcast Sponsors: Learn how to inspire advocacy https://www.thecargoagency.com Register for a free pilot program with Feedback Now https://marketing-info.feedbacknow.com/free-pilot Learn more about Stone Mantel https://www.stonemantel.co Sign up for the Experience Strategist Substack here: https://theexperiencestrategist.substack.com
In this episode of The Natural Health Podcast, Mihaela interviews Vladimir, an entrepreneur with a remarkable story of overcoming childhood cancer and building successful companies. They discuss his passion for travel, the importance of cultural immersion, and how his health journey led him to innovate in the oral care industry. Vladimir shares insights on the science behind toothpaste ingredients, the role of micronutrients in oral health, and the future of health products that aim to replace traditional supplements. The conversation highlights the connection between oral health and overall wellness, emphasizing the need for clean, effective products that support the body's natural resilience.TakeawaysVladimir's love for travel enhances his cultural experiencesOvercoming childhood cancer shaped Vladimir's perspective on lifeEntrepreneurship was a natural progression for Vladimir after corporate workVladimir's health journey inspired his current company, Better & BetterOral care is often overlooked in holistic health discussionsHydroxyapatite is a natural alternative to fluoride in toothpasteCavities can repair themselves with proper care and nutritionVladimir emphasizes the importance of continuous improvement in product development00:00 Cultural Immersion Through Travel03:11 Overcoming Childhood Cancer05:59 The Entrepreneurial Journey Begins09:03 Building a Crowdfunding Platform11:59 Innovating in the Art World14:59 Transitioning to Health and Wellness17:46 Revolutionizing Oral Care20:58 Deconstructing Traditional Toothpaste24:01 Creating a Healthier Alternative26:42 Evolving Toothpaste Formulations29:02 The Oral Microbiome and Its Importance32:22 Choosing Effective Ingredients36:39 The Science Behind Nutrient Absorption38:38 Hydroxyapatite: A Natural Alternative to Fluoride42:21 Cavity Repair and Oral Health45:40 The Role of Xylitol in Oral Care48:06 Future Directions for Better & Better
Welcome to the Securing Our Future podcast, where we explore the synergy between commercial innovation and national security. In this episode, we sit down with Dawn Meyerriecks, an expert with over 40 years of experience in government and industry, to discuss the profound technological advancements from Desert Storm to AI and quantum computing. Dawn shares insights into the adoption of new technologies, the role of government and private sectors, and the importance of finding the right champions for innovation. We also delve into the emerging field of biotechnology and its transformative implications for national security. Join us for an engaging conversation that bridges the gap between innovation and security.00:00 Introduction to Securing Our Future Podcast00:41 Guest Introduction: Dawn's Storied Career01:05 Technological Evolution and National Security02:49 Challenges of Rapid Technological Change04:27 Leadership and Innovation in Government06:37 Startups and Government Collaboration12:34 Biotechnology and National Security19:00 Future Directions and Personal Reflections25:20 Closing Remarks and Acknowledgements
In this episode of Iron Culture, hosts Eric Helms and Michael Zourdos engage with Dr. Zac Robinson to discuss his dissertation research on the effects of resistance training volume on muscle adaptations. The conversation delves into the complexities of individual responses to training, the importance of research design, and the implications of findings for coaching practices. They emphasize the need for caution in interpreting data and the evolving nature of sports science, highlighting the significance of collaboration and flexibility in training approaches. Chapters 00:00 Introduction and Guest Introduction 06:25 The PhD Journey and Team Dynamics 11:32 Dissertation Overview and Research Focus 18:43 Research Methodology and Individual Variability 26:50 Understanding Individual Response Variation in Training 32:09 Study Design: Isolating Variables in Training Responses 37:33 The Importance of Replication in Research 42:40 Findings 53:41 Limitations and Implications of the Study 01:00:17 Genetics and Individual Response Variability 01:02:59 The Dose-Response Relationship in Training 01:06:25 Shifting Perspectives on Training Individualization 01:11:00 The Role of Sports Science in Coaching 01:19:51 Future Directions in Resistance Training Research
In this episode of Remodelers on the Rise, Kyle, Bailey, and Kassi share highlights from the recent Rise Conference. From roundtables that sparked powerful conversations to breakout sessions on AI and marriage, they reflect on moments of learning, laughter, and even tears. You'll hear about community connections, sponsors, standout sessions, and a surprise new employee benefit—plus a big announcement about the 2026 Rise Conference. ----- Thank you to our RISE Conference Sponsors: CGN (Contractor Growth Network) Builder Funnel JobTread DreamMaker Bath & Kitchen Contractor in Charge Squirrel Solutions Seabrook Design Co. ----- Explore the vast array of tools, training courses, a podcast, and a supportive community of over 2,000 remodelers. Visit Remodelersontherise.com today and take your remodeling business to new heights! ----- Takeaways The Rise Conference had over a hundred attendees and multiple breakout sessions. The three I's of the conference were Ideas, Inspiration, and Implementation. Engagement during roundtables was high, with attendees sharing valuable insights. Feedback from attendees highlighted the positive energy and collaborative culture. A new employee benefit was introduced: a tattoo stipend for team members. Future events are planned, including an implementation check-in call and another Rise Conference in 2026. The importance of community among remodelers was emphasized throughout the conference. Attendees left with actionable ideas and commitments to implement in their businesses. The hosts shared personal stories and moments that made the conference memorable. The podcast encourages creativity in employee benefits and community building. ----- Chapters 00:00 Introduction to the Rise Conference Recap 03:05 Key Themes and Highlights of the Conference 06:11 Standout Moments and Personal Stories 08:57 Engagement and Community Building 12:00 Implementation and Action Plans 15:01 Feedback and Future Directions 22:42 Exploring the Henry Ford Museum and Attendee Feedback 23:59 The Importance of Focus and Implementation 26:00 Positive Energy and Culture at the Conference 27:03 Stepping Out of Comfort Zones 27:52 New Employee Benefits and Team Bonding 29:55 Creative Employee Benefits: The Tattoo Stipend 34:00 Looking Ahead: Future Conferences and Offerings
In this episode, Dr. Jockers sits down with Dr. Joseph Antoun to unpack how fasting strategies, including fasting-mimicking diets, can rejuvenate immune cells, slow down inflammaging, and support overall healthy aging. You'll discover how chronic inflammation accelerates aging, why old “zombie” cells cause damage, and how fasting helps clear them out while replacing them with stronger, more resilient ones. The conversation also dives into immunosenescence, what happens when immune cells age, and how this process links to conditions like cancer, cardiovascular disease, and autoimmune disorders. Dr. Antoun also explains the delicate balance between growth and repair in the body—and why our modern eating patterns keep us stuck in constant growth mode. By leveraging targeted fasting protocols, we can push our bodies toward autophagy, boost cell repair, and open the door to a healthier, longer life. In This Episode: 00:00 Introduction to Fasting and Cellular Rejuvenation 00:48 Guest Introduction: Dr. Joseph Antoun 04:25 Understanding Chronic Inflammation and Inflammaging 10:10 The Role of Nutrition in Aging and Immune Health 13:13 Fasting Mimicking Diet: Science and Benefits 23:32 Fasting and Autoimmune Diseases 24:35 The Role of Stomach Acid in Digestion 26:28 ProLon and Biological Age Reduction 30:15 ProLon for Diabetes and Chronic Conditions 32:06 How to Use ProLon Effectively 38:06 Current Research and Future Directions 40:49 The Importance of Fasting in Human Health 42:39 Conclusion and Final Thoughts Looking for a clean, nutrient-packed snack? Paleo Valley's Grass-Fed Meat Sticks are free from sugar, additives, and preservatives—just pure protein and healthy fats to keep cravings in check and support muscle and immune health. They come in delicious flavors like Original, Garlic Summer Sausage, and Teriyaki, and they're even kid-approved. Try them today and get 15% off your order at paleovalley.com/jockers. Think heartburn comes from too much stomach acid? Think again. Most digestive issues actually stem from too little stomach acid. That's why I recommend Just Thrive Digestive Bitters—they naturally stimulate stomach acid, bile, and enzymes to improve digestion, reduce bloating, and boost nutrient absorption.Save 20% off your order with code JOCKERS at justthrivehealth.com. "As we age, our immune cells become more sluggish, but fasting helps rejuvenate them, giving you a youthful immune response." Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio Resources: Get 15% off Paleovalley: paleovalley.com/jockers – Use code JOCKERS Save 20% on Just Thrive: justthrivehealth.com – Use code JOCKERS Connect with Dr. Joseph Antoun: Website: https://www.glownaturalwellness.com/ Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https:/www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/
This week, the girlies log on to discuss the strange and somewhat evil journey of content streaming. They track the rise from radio to Napster to Netflix, expose how labels teamed up with platforms to rob artists blind, and unpack how mood playlists and background noise culture encourage you to passively consume your music, not listen to it. They also hear from binchies who have done away with streaming entirely, and talk about hopeful alternatives for finding and interacting with art you love. Digressions include: Matt Rife's new haunting business venture, Katy Perry's stay at the Khia Asylum, and unfortunately, hitting the Sydney Sweeney button. This episode was produced by Julia Hava and Eliza McLamb and edited by Livi Burdette. Research assistance from Kylie Finnigan. To support the podcast on Patreon and access 50+ bonus episodes, mediasodes, zoom hangouts and more, visit patreon.com/binchtopia and become a patron today. SOURCES A cultural lineage of streaming Adolescent Mental Health in the Digital Age: Facts, Fears and Future Directions be your own algorithm (video) Binge Watching as a Young Adult Linked to Cognitive Impairment: Study Mood Machine by Liz Pelly Netflix Reveals the Shows That You Binge Watched the Fastest Netflix's 'Skip Intro' Button Makes TV Ever More Like an App Stream a Little Dream: How Netflix Turned Our Culture into Content Streaming Culture by David Arditi Swedish composer becomes Spotify's most-famous musician you've never heard of The Algorithm Killed the Radio Star by Eliza McLamb The Best Streaming Services For 2025 The Death of the Artist by William Deresiewicz The Death of the Artist—and the Birth of the Creative Entrepreneur The Evolution and Impact of Streaming Services: Changing the Media Landscape The Ghosts in the Machine The Oxford Handbook of Radio and Podcasting The Right to Art by Eliza McLamb The Telephonoscope (1879) This ‘secret' composer is behind 650 fake artists on Spotify. His music has been streamed 15bn times on the platform (report) 83% of U.S. adults use streaming services, far fewer subscribe to cable or satellite TV
Gardens - Web3 Governance Framework Gardens - Bottom-Up Governance for Web3 Ecosystems Gardens is a bottom-up governance framework designed to support web3 ecosystems. It provides coordination infrastructure and funding mechanisms that help grow networks of public goods—run by the individuals and communities that understand them best.
Beau Martonik chats with James Yates about hunting, gear optimization, and his Arrow Ballistic Study. They dive into everything that was included in the most comprehensive hunting arrow study ever done, including arrow diameter, vane type, noise, drag, lift recovery, and more. Yates also discusses broadheads, comparing their design and efficiency. They conclude with tips on preparation in hunting and an introduction to his YouTube channel, "Yates in the Backcountry," which aims to enhance hunters' understanding of gear performance. Topics: 00:00:00 - Introduction 00:05:16 – Background On James 00:21:06 – Arrow Ballistics Study 00:26:38 – The Science Behind Arrow Design 00:39:41 – Insights on Vane Noise 00:59:18 – The Importance of Preparation 01:05:24 – Arrow Diameter and Performance 01:19:42 – Measuring Lift Recovery 01:24:29 – The Role of Broadheads 01:46:17 – Future Directions in Archery Studies Resources: James Yates Links: Western Hunter Arrow Ballistics Study Results Yates in the Backcountry YouTube Yates in the Backcountry IG Instagram: @eastmeetswesthunt @beau.martonik Facebook: East Meets West Outdoors Shop Hunting Gear and Apparel: https://www.eastmeetswesthunt.com/ YouTube: Beau Martonik - https://www.youtube.com/channel/UCQJon93sYfu9HUMKpCMps3w Partner Discounts and Affiliate Links: https://www.eastmeetswesthunt.com/partners Amazon Influencer Page https://www.amazon.com/shop/beau.martonik Learn more about your ad choices. Visit megaphone.fm/adchoices
Can you manipulate blood flow in the tumor microenvironment to optimize drug delivery? In this episode of the BackTable Podcast, interventional oncologist Dr. Zachary Berman (UC San Diego) joins host Dr. Christopher Beck to discuss real-world applications of pressure-enabled drug delivery in local, regional liver-directed therapies like TACE and Y90.---This podcast is supported by:TriSalus Life Scienceshttp://trinavinfusion.com/---SYNPOSISThe conversation begins with an overview of the tumor microvascular environment, focusing on the abnormal nature of the new vessels that feed tumors. They then discuss the genesis of pressure-enabled drug delivery and the theory behind its efficacy. Dr. Berman explains the TriNav catheter's micro-valve design, its anti-reflux properties, and how these features enhance tumor drug delivery. He walks through his own procedure technique, comparing and contrasting it to standard embolization, and details the utility of pressure-enabled drug delivery in lobar radioembolization and larger tumors. They also explore the benefits of both balloon occlusion and microvalve catheters.Real-world cases—including neuroendocrine tumors, segmental HCC, and more—illustrate the thought process around when to use specialized technologies. The episode wraps up with a discussion of the future implications for this technology in other pathologies, cost considerations, and the potential for enhancing drug delivery with innovative approaches.---TIMESTAMPS00:00 - Introduction01:39 - The Tumor Microenvironment06:59 - Pressure-Enabled Drug Delivery Explained09:37 - Technical Aspects of Pressure-Enabled Catheters21:48 - Case 1: Grade 3 Neuroendocrine Tumor34:06 - Case 2: Hepatocellular Carcinoma with Tumor and Vein36:01 - Case 3: TACE for Segmental HCC in Decompensated Cirrhosis38:58 - Case 4: Large Heterogenous Cholangiocarcinoma40:40 - Case 5: Lobar Neuroendocrine Tumor42:38 - Case 6: Segmental HCC with Central Necrosis47:52 - Best Practices and Technical Considerations57:52 - Future Directions in Pressure-Directed Embolotherapy59:48 - Conclusion and Final Thoughts---RESOURCESJVIR 2024 Jaroch et al.:https://pubmed.ncbi.nlm.nih.gov/38969336/
August 12, 2025: Dr. Zafar Chaudry, SVP, CDIO, and AI Officer, speaks with Dr. Vittorio Gallo, Chief Scientific Officer at Seattle Children's Research Institute, about the transformation happening in pediatric research. As healthcare shifts from traditional lab work to data-driven science, how are research institutions keeping pace with the explosion of information they're generating? Vittorio discusses breakthrough therapies currently in development, including the first clinical trial for cell immunotherapy in pediatric lupus and innovative approaches to treating neonatal brain injuries. But with massive datasets requiring decades of storage and AI models now identifying developmental disorders through behavioral analysis, what does this mean for the relationship between technology teams and researchers?Key Points:03:40 Innovative Pediatric Therapies10:53 Future Directions in Data Science16:02 Future Projects and AI Applications22:44 Mentorship and Advice for Young ScientistsX: This Week HealthLinkedIn: This Week HealthDonate: Alex's Lemonade Stand: Foundation for Childhood Cancer
In this podcast episode, Dr. John Holcomb discusses the management of traumatic brain injury (TBI) and the innovative use of plasma as a treatment option. He emphasizes the importance of understanding the glycocalyx and its role in preventing edema and managing intracranial pressure (ICP). The conversation also highlights the limitations of current guidelines in TBI treatment and the need for practical considerations in administering plasma. Dr. Holcomb advocates for a shift in practice towards using plasma early in the treatment process to improve patient outcomes.TakeawaysPlasma is used as a drug to prevent edema in TBI patients.The glycocalyx plays a crucial role in brain injury management.Preventing increased ICP is more effective than treating it.Current guidelines often lag behind clinical practice.Understanding the physiology behind treatments is essential for medics.Monitoring blood pressure is critical in TBI management.Plasma can repair the blood-brain barrier and reduce edema.Practical considerations are necessary for administering plasma in the field.The outcomes of TBI treatment should focus on functional recovery.Future directions in TBI management include more research on plasma use.Chapters00:00 Introduction to TBI Management and Plasma Use03:04 Understanding Plasma as a Drug for TBI05:39 The Role of Glycocalyx in Brain Injury08:47 Preventing Edema and Managing ICP11:31 Guidelines and Their Limitations in TBI Treatment14:33 Practical Considerations for Administering Plasma17:29 The Importance of Patient Monitoring and Judgment20:44 Outcomes and Future Directions in TBI ManagementFor more content, go to www.prolongedfieldcare.orgConsider supporting us: patreon.com/ProlongedFieldCareCollective or www.lobocoffeeco.com/product-page/prolonged-field-care
Summary In this episode, Johnny Owens interviews Jordan Sabarin, a strength and conditioning coach for the Detroit Pistons and expert in blood flow restriction (BFR) training. They discuss Jordan's journey from being a professional basketball player to pursuing a PhD in BFR, the differences in strength and conditioning philosophies between the NBA and Europe, and the practical applications of BFR in athletic training. The conversation delves into Jordan's dissertation study, which assesses the effects of BFR on performance and recovery in elite basketball players, as well as the qualitative feedback from players regarding their experiences with BFR. They also explore future directions for BFR research and its integration into NBA training regimens. Chapters 00:00 Introduction to Blood Flow Restriction in Athletics 03:13 Jordan Sabarin's Background and Journey 05:09 Differences in Strength and Conditioning Philosophies 06:52 The Rise of Blood Flow Restriction Training 08:50 Pursuing a PhD in Blood Flow Restriction 10:40 Research Questions and Study Design 12:44 Understanding the NBA Training Schedule 15:31 Study Hypothesis and Objectives 18:50 Methodology: Exercises and Protocols 21:18 Using the Omni-Res Scale for Measurement 22:55 Objective Measures and Data Collection 26:13 Qualitative Insights from Players 30:47 Quantitative Findings and Discussion 41:16 Exploring Resistance Training and Recovery 42:23 Qualitative Observations in Training 43:03 Comparing BFR and Traditional Training 45:00 Athlete Preferences and Training Discomfort 46:35 Future Research Directions in BFR 49:56 Application of BFR in the NBA 52:22 Pre-Competition Priming with BFR 54:28 BFR for Tendon Health and Pain Management 56:05 BFR in Rehabilitation and Performance 59:55 Integrating BFR into Traditional Lifts 01:02:06 Traveling with BFR Devices 01:06:39 Future Directions and Research in BFR Podcast Intro Attribution Song: Legendary Music by: CreatorMix.com Video: https://youtu.be/_oaZzkn0bW4 Podcast Outro Attribution Song: Smoke Rising Music by: CreatorMix.com Video: https://youtu.be/_oaZzkn0bW4
Episode 309 hosts Dr Shino Bay (Dermatologist from Miami, USA) Shino joins us in the 28th chapter of our series called 'The Injector Diaries'. These episodes feature in depth conversations, stories and experiences from injectors around the globe. Each injector brings their own unique take on things and we showcase every level of type of injector, from newbies to masters. We'll explore how and why they chose to inject, why they favour using certain products, look under the hoods of their clinics and aim to inspire our injector listeners. 00:00 Introduction to Inside Aesthetics 00:47 Welcome to The Injector Diaries Chapter 28 02:48 Introducing Today's Guest: Shino Bay 03:18 Shino Bay's Early Life and Inspiration 05:17 Journey to Becoming a Doctor in the USA 08:29 Discovering Aesthetic Medicine 13:12 Pioneering Techniques and Training 17:27 Current Practice and Patient Demographics 19:27 Industry Insights and Future Directions 24:50 The Challenges of Looking Younger 25:46 Consultation Process Tips 26:54 The Importance of Patient Education 30:24 Spirituality and Aesthetics 40:10 Public Speaking and Personal Growth 44:39 Conclusion and Teaser for Next Episode JOIN OUR PATREON FOR EXCLUSIVE SUBSCRIBER-ONLY PODCASTS, WEEKLY EDUCATIONAL CONTENT & JOIN OUR WHATSAPP COMMUNITY CLICK HERE TO BROWSE OUR IA OFFERS FOR DISCOUNTS & SPECIALS CLICK HERE IF YOU'RE A BRAND OR COMPANY & WANT TO WORK WITH US CLICK HERE TO APPLY TO BE A GUEST ON OUR PODCAST CONTACT US
In this series, host Catherine Glass speaks with David Cosio about the complex and often overlooked relationship between anxiety and chronic pain. They explore the neurobiological underpinnings of both conditions, how they influence each other, and what the future of integrated pain management may look like, from AI to psychedelics and beyond. 0:47 - Acceptance and Commitment Therapy 3:17 - Anxiety and Chronic Pain 5:50 - ‘Let Them' Concept 8:09 - David's Book 10:07 - Book Section Recommendations 11:20 - Lifestyle Factors 12:00 - Grief and Chronic Pain 14:06 - Delayed Reaction to Grief
How do you effectively treat your bladder cancer population with an insufficient supply of BCG? Dr. Amy Luckenbaugh, a urologic oncologist at Vanderbilt University Medical Center, joins host Dr. Ruchika Talwar to highlight challenges and solutions to managing bladder cancer amidst ongoing BCG shortages. --- This podcast is supported by an educational grant from UroGen Pharma. --- SYNPOSIS Dr. Luckenbaugh and Dr. Talwar delve into the history and significance of BCG in bladder cancer treatment, exploring the reasons behind the shortages and discussing various coping strategies, including split dosing and alternative intravesical therapies like gemcitabine, docetaxel, and the new mitomycin hydrogel. The conversation also covers emerging treatments for high-risk patients, the role of radical cystectomy, and the importance of standardization and innovation in dealing with medication shortages. Dr. Luckenbaugh highlights the importance of patient quality of life, cost considerations, and the need for resilient pharmaceutical supply chains. --- TIMESTAMPS 00:00 - Introduction01:56 - History and Importance of BCG in Bladder Cancer03:21 - Challenges and Shortages of BCG06:36 - Managing BCG Shortages in Clinical Practice12:33 - New Alternatives and Treatments for Bladder Cancer23:28 - The Role of Cystectomy in Bladder Cancer Treatment26:12 - Future Directions and Final Thoughts --- RESOURCES BCG Shortage AUA Recommendations:https://www.auanet.org/about-us/bcg-shortage-info Reduced-dose bacillus Calmette-Guérin (BCG) in an era of BCG shortage: real-world experience from a tertiary cancer centre: https://pmc.ncbi.nlm.nih.gov/articles/PMC11951178/ Bladder Cancer Advocacy Network (BCAN):https://bcan.org/ Primary Chemoablation of Recurrent Low-Grade Intermediate-Risk Nonmuscle-Invasive Bladder Cancer With UGN-102: A Single-Arm, Open-Label, Phase 3 Trial (ENVISION)https://pubmed.ncbi.nlm.nih.gov/39446087/b FDA Approves Intravesical Mitomycin in Non–Muscle-Invasive Bladder Cancer:https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-mitomycin-intravesical-solution-recurrent-low-grade-intermediate-risk-non-muscle TAR-200 - SunRISe-3 Study:https://www.jnjmedicalconnect.com/products/tar-200/medical-content/tar-200-sunrise-3-study First results from TAR-200 - SunRISe-1 Study:https://www.jnj.com/media-center/press-releases/johnson-johnsons-tar-200-monotherapy-achieves-high-disease-free-survival-of-more-than-80-percent-in-bcg-unresponsive-high-risk-papillary-nmibcN-803 Plus BCG Treatment for BCG-Naïve or -Unresponsive Non-Muscle Invasive Bladder Cancer: A Plain Language Review:https://pmc.ncbi.nlm.nih.gov/articles/PMC11524197/
Summary In this truncated replay from a session at the 2025 SF Derm Annual Conference, Dr. Daniel Butler, Dr. Lawrence Eichenfield, Dr. Jason Hawkes, Dr. Shyam Joshi, and Dr. Bob Geng discuss the workup for chronic urticaria, focusing on testing approaches, the role of biomarkers, and insights into immune deficiencies. These panelists share their experiences and guidelines, emphasizing the importance of symptomatic management and the variability of lab results in clinical practice. Takeaways - Initial workup for chronic urticaria often does not require specific testing. - Testing may be justified if standard treatments fail. - International guidelines differ from US guidelines regarding testing. - Biomarkers currently available are not reliable for treatment decisions. - Symptomatic management should be prioritized over extensive testing. - Clinical trials show variability in lab results over time. - Excessive lab testing can lead to confusion and unnecessary anxiety for patients. - Understanding patient history is crucial in diagnosing immune deficiencies. - The role of family history is significant in identifying X-linked conditions. - Collaboration among dermatologists is essential for advancing treatment approaches. Chapters 00:00 - Introduction to Chronic Urticaria Workup 02:47 - Testing Approaches and Guidelines for Chronic Urticaria 05:41 - The Role of Biomarkers in Treatment Decisions 08:16 - Clinical Insights on Immune Deficiencies 11:14 - Variability in Lab Results and Clinical Trials 14:07 - Conclusion and Future Directions in Dermatology
In this episode of the Radical Health Rebel podcast, Leigh Brandon interviews Ben O'Loghlin, an expert in the Alexander Technique. They discuss Ben's personal journey with chronic pain and how he discovered the Alexander Technique as a solution. The conversation delves into the role of the brain in muscle tension, the importance of active engagement in healing, and the misconceptions surrounding chronic pain. Ben emphasizes the significance of self-management and the mind-body connection in pain perception. They also explore how the Alexander Technique can benefit musicians by enhancing their performance through improved posture and relaxation. The episode concludes with Ben sharing his future plans for an online course and innovative approaches to teaching the Alexander Technique.Chapters00:00 The Journey to Alexander Technique03:03 Understanding the Alexander Technique05:58 Active vs Passive Treatments08:46 Challenging Age-Related Pain Myths11:40 Misconceptions About Back Pain14:44 The Role of the Medical Model17:38 Exploring Modalities for Pain Relief20:51 The Mind-Body Connection in Pain23:46 Navigating Automatic and Voluntary Systems33:43 Understanding Automatic Postural Control40:39 The Role of Directions in Alexander Technique47:42 Personal Transformations Through Alexander Technique54:28 Posture, Movement, and Performance in Musicians01:00:37 Engineering Perspective on Body Mechanics01:04:18 Future Directions and Innovations in Alexander TechniqueYou can find Ben @:https://www.backrepublic.comhttps://youtube.com/@benologhlinhttps://facebook.com/ben.ologhlinSend us a textSupport the showDon't forget to leave a Rating for the podcast!You can find Leigh @: Leigh's website - https://www.bodychek.co.uk/ Chronic Pain Breakthrough Blueprint - https://www.bodychek.co.uk/freepainguide/ Leigh's courses: StickAbility - https://stickabilitycourse.com/ Mastering Client Transformation (professional course) - https://www.functionaldiagnosticnutrition.com/mastering-client-transformation/
Guest: Robert Johnson MD DMD https://duotoothpaste.com/?srsltid=AfmBOorY6XC93IxhnT-RogfUks5RkbcpCMvUQXAjWtLvYFdImX4MazTW Host: Serv Wahan MD DMD https://www.drwahan.com/ keywords Duo Toothpaste, Hydroxyapatite, Fluoride, Oral Health, Sustainable Dental Care, Innovative Toothpaste, Dental Products, SLS-Free, Oral Hygiene, Dental Technology, fluoride, fluoride-free, nano-hydroxyapatite, remineralization, tablet toothpaste, Dr. Wahan, Serv Wahan, Robert Johnson MD DMD, Fluoride-free toothpaste summary In this conversation, Dr. Bobby Johnson discusses the innovative Duo Toothpaste, a tablet-based toothpaste developed with a focus on sustainability and oral health. He shares insights into the concept behind Duo, the science of nano-hydroxyapatite as an alternative to fluoride, and the benefits of using SLS-free products. The discussion also covers the business journey of Duo and the importance of customer retention in the dental care market. takeaways Duo Toothpaste is a tablet-based product that aims to innovate oral hygiene. The idea for Duo was born from a desire to make brushing teeth exciting. Nano-hydroxyapatite is an effective alternative to fluoride for remineralizing teeth. Duo Toothpaste is packaged in a recyclable glass jar, reducing plastic waste. The product is SLS-free, making it gentler on the oral microbiome. Duo offers different tablet types, including those with added caffeine and vitamins. The company focuses on sustainability and reducing carbon footprint. Customer retention is high, indicating satisfaction with the product. Duo Toothpaste is safe for children, addressing concerns about fluoride ingestion. The conversation highlights the importance of ongoing research in dental health. titles Revolutionizing Oral Care with Duo Toothpaste The Science Behind Duo Toothpaste Sound Bites "Duo is a tablet toothpaste." "Fluoride is a hot topic." "SLS is an irritant." Chapters 00:00Introduction to Duo Toothpaste 02:57The Concept Behind Duo Toothpaste 04:49Fluoride vs. Hydroxyapatite: A Deep Dive 05:50The Science of Nano-Hydroxyapatite 08:40Benefits of Nano-Hydroxyapatite Over Fluoride 09:12Understanding Tooth Sensitivity and Treatment Options 11:32The Role of Surfactants in Oral Care 13:36Innovations in Toothpaste: From Tablets to Foams 15:54The Benefits of Caffeine and Vitamins in Toothpaste 18:21Fluoride vs. Nano-Hydroxyapatite: A New Perspective 21:21Business Insights: Launching a Dental Product 23:22Final Thoughts and Future Directions
In the return episode of Delta Dispatches, host Simone Maloz is joined by Dr. Alisha Renfro and Steve Cochran to discuss Louisiana's coast, its people, wildlife and jobs, and why restoring it matters. Today we explore the ecological, economic, and community significance of the Louisiana's coast and the challenges and implications following the state's decision not to move forward with the Mid-Barataria Sediment Diversion. 01:47 Importance of Louisiana's Coast 02:28 Milestones and Successes in Coastal Restoration 14:08 The Role of the Mississippi River 19:43 Introduction of Steve Cochran 24:09 The Importance of Louisiana's Coastal Program 27:09 Challenges and Changes in Coastal Restoration 29:23 Implications of the Mid-Barataria Decision 37:26 Reflections and Future Directions
SummaryIn this conversation, Jennifer Darling and Warren Olson discuss the evolution of fire protection, the importance of continuing education, and the role of mentorship in the fire service. They explore Warren's extensive career, his involvement with the NFPA, and the challenges faced in fire safety regulations. The discussion highlights the significance of teaching and the impact of major fire incidents on current safety practices.takeawaysMICE aims to simplify continuing education for providers and administrators.Warren Olson has over 50 years of experience in fire protection.He emphasizes the importance of mentorship in the fire service.Generational changes have improved firefighter health and safety.Teaching has been a passion for Warren throughout his career.NFPA technical committees play a crucial role in developing fire safety codes.Challenges in fire safety regulations are influenced by special interest groups.Lessons from past fire incidents shape current safety practices.The pendulum of fire safety regulations swings with public perception.Warren's journey reflects the importance of continuous learning in fire protection.Sound Bites"I've been doing this a long time.""Teaching gives me the greatest joy.""The codes are being chipped away."Chapters00:00Introduction to MICE and TrackMyCE.io01:25Warren Olson's Journey in Fire Protection05:55Career Progression and Experiences in Fire Service11:52Generational Changes in Fire Service17:52The Importance of Teaching and Mentorship23:52Involvement with NFPA Technical Committees29:54Challenges in Fire Safety Regulations35:56Lessons from Major Fire Incidents41:33Reflections on Fire Safety and Future Directions
In this episode of Psychedelics Today, Joe Moore sits down with Chad Charles — educator, mentor, and practitioner specializing in 5-MeO-DMT therapy. Chad shares his decade-long journey working with 5-MeO-DMT, emphasizing the importance of: Practitioner training and mentorship Personalized, therapeutic alliances The nuanced understanding of dissociative states Ethics in standardized clinical dosing A trauma-informed approach to psychedelic care He also introduces his upcoming research project, analyzing 500+ one-on-one sessions to illuminate best practices and ethical frameworks in the 5-MeO-DMT space. This is a must-listen for anyone passionate about harm reduction, responsible facilitation, and the future of psychedelic therapy.
When it comes to spinal oncology, no single specialty holds all the answers. In this episode of the BackTable Podcast, host Dr. Alexa Levey, an interventional radiologist from Yale School of Medicine, is joined by Dr. Mark Amsbaugh, a radiation oncologist, and Dr. Ran Lador, an orthopedic spine surgeon, both from the University of Texas McGovern Medical School. The discussion explores complexities and innovations in the multidisciplinary treatment of spinal tumors. --- SYNPOSIS Dr. Ambsbaugh and Dr. Lador highlight their cohesive, patient-centered approach at Memorial Hermann, integrating various specialties including surgery, radiation oncology, and interventional radiology. The episode emphasizes the importance of collaborative techniques, advances in minimally invasive surgeries, the role of stereotactic radiosurgery, and the critical nature of personalized patient care in improving outcomes for patients with spinal tumors. --- TIMESTAMPS 00:00 - Introduction01:20 - Multidisciplinary Approach to Spinal Tumors at Memorial Hermann10:22 - Surgical Techniques and Timing for Radiation Treatments 12:25 - Approach to Collaborative Treatment Planning25:45 - Connection Between Surgical and Radiation Oncology in Patient Care31:08 - The Role of Vertebral Augmentation in Spinal Oncology40:08 - Multimodal Pain Management Strategies47:35 - Thoughts on Future Directions in Spinal Oncology and Conclusion --- RESOURCES Dr. Mark Amsbaugh, MDhttps://med.uth.edu/neurosciences/dr-mark-j-amsbaugh-md/ Dr. Ran Lador, MDhttps://med.uth.edu/ortho/2022/11/02/ran-lador-md/ Dr. Alexa Levey, MDhttps://medicine.yale.edu/profile/alexa-levey/
In this episode of the PFC Podcast, host Dennis interviews Jeff Ory, a recent medical graduate and former infantryman, discussing the critical topic of tension pneumothorax and the techniques for needle decompression. They explore the historical data on tension pneumothorax mortality, the effectiveness of different decompression sites, and the risks associated with the procedure. The conversation also delves into the importance of ongoing training for medics, the debate over who should be trained in needle decompression, and the best practices for chest tube placement. The episode concludes with thoughts on the future of trauma care and the need for continuous improvement in medical training.TakeawaysTension pneumothorax is primarily a blood flow issue, not a respiratory one.The fifth intercostal space is often preferred for needle decompression due to safety and accuracy.Hubbing a needle during decompression poses significant risks.Many patients do not show objective improvement after needle decompression.Training in emergency procedures must be continuous to maintain skills.The placement of chest tubes is debated, with various opinions on the best approach.Most patients with pneumothorax also have other injuries that complicate treatment.Emergency procedures should be simplified for better retention and execution.The risk of injury from needle decompression is a significant concern.Emergent decompression is crucial for patient survival in trauma situations.Chapters00:00 Introduction to the Podcast and Guest01:08 Understanding Tension Pneumothorax07:04 Needle Decompression Techniques and Efficacy12:20 Risks and Complications of Needle Decompression20:03 Training and Skill Retention in Emergency Medicine30:44 Debate on Needle Decompression in Military Training39:04 Chest Tube Placement and Techniques49:22 Conclusion and Future Directions in Trauma CareThank you to Delta Development Team for in part, sponsoring this podcast.deltadevteam.comFor more content, go to www.prolongedfieldcare.orgConsider supporting us: patreon.com/ProlongedFieldCareCollective or www.lobocoffeeco.com/product-page/prolonged-field-care
Hodlbod brings a unique perspective, bridging the old and the new, with a focus on a healthier relationship between users and the digital world.Hodlbod on Nostr: https://primal.net/p/nprofile1qqsf03c2gsmx5ef4c9zmxvlew04gdh7u94afnknp33qvv3c94kvwxgsm3u0w6 His Book: https://building-nostr.coracle.social Coracle: https://coracle.socialFlotilla: https://flotilla.social/His other apps: https://stuff.coracle.social EPISODE: 170BLOCK: 907160PRICE: 858 sats per dollar(00:00:01) Tesla's Bitcoin Holdings and Opportunity Costs(00:01:11) Happy Bitcoin Friday(00:03:01) Guest Introduction: Hodlbod(00:04:20) Challenges of Streaming and Notifications(00:06:30) Decentralized Technology and Social Media(00:10:04) Push Notifications and Privacy Concerns(00:15:00) Reforming Technology and Social Media(00:20:00) Decentralization and Political Dynamics(00:25:00) Nostr's Adoption and Future Prospects(00:33:00) Nostr's Unique Protocol and Challenges(00:40:00) AI's Role in Development and Vibe Coding(00:50:00) Micro Apps vs. Holistic Experiences on Nostr(01:00:00) Social Media Addiction and User Experience(01:10:00) Group Chats and Community Building(01:20:00) Signal's Influence and Privacy Concerns(01:30:00) Monetization and Sustainability on Nostr(01:50:00) Nostr's Development and Future Directions(02:00:00) Book Release: Building NostrVideo: https://primal.net/citadelsupport dispatch: https://citadeldispatch.com/donate nostr live chat: https://citadeldispatch.com/stream odell nostr account: https://primal.net/odell dispatch nostr account: https://primal.net/citadel ten31 x account: https://x.com/ten31funds youtube: https://www.youtube.com/@CitadelDispatch podcast: https://serve.podhome.fm/CitadelDispatch stream sats to the show: https://www.fountain.fm/ rock the badge: https://citadeldispatch.com/shop learn more about me: https://odell.xyz
In this episode of Psychedelics Today, Joe Moore sits down with Alan Davis, Associate Professor at Ohio State University, to explore the evolving landscape of Ibogaine research and its therapeutic potential. Alan offers a deep dive into the Iboga Patient Survey, a groundbreaking initiative collecting real-world data on the safety and efficacy of Ibogaine—particularly for those struggling with substance use disorders and mental health challenges. The conversation sheds light on the need for rigorous, community-informed research that could pave the way toward FDA approval and increased access for patients, including veterans dealing with trauma. They also discuss the complexities of clinical trials, the tension between state and federal regulations, and the growing influence of corporate interests in psychedelic research. Alan emphasizes the importance of ethical transparency, community collaboration, and maintaining scientific integrity as the field grows. If you're curious about the intersection of psychedelic medicine, clinical research, and patient safety, this is a must-listen episode. Topics Covered 00:00 – Introduction and Guest Welcome 00:53 – Reflecting on COVID-19's Psychological Impact 01:29 – Introducing the Iboga Patient Survey 01:46 – History and Goals of Ibogaine Research 02:41 – Challenges in Conducting Clinical Trials 03:14 – Importance of Real-World Safety Data 06:55 – Personal Interest in Ibogaine 08:56 – Veterans and Trauma: A Personal Connection 10:53 – Reintegration and Emotional Processing 15:29 – Survey Participation and Accessibility 18:25 – Building Partnerships and Overcoming Challenges 21:06 – Ensuring Safety and Transparency 31:49 – Community and Academic Collaboration 33:06 – Survey Design and Future Research Directions 36:50 – Momentum in Psychedelic Research 37:48 – State vs. Federal Regulation 39:23 – Challenges in Psychedelic Treatment 43:01 – Corporate Interests and Scientific Objectivity 47:20 – Ketamine and Collaborative Research 51:56 – Ibogaine Patient Survey 57:55 – Psychedelics and Pain Research 01:07:22 – Conclusion and Future Directions
No Priors: Artificial Intelligence | Machine Learning | Technology | Startups
In the generative AI revolution, quality data is a valuable commodity. But not all data is created equally. Sarah Guo and Elad Gil sit down with SurgeAI founder and CEO Edwin Chen to discuss the meaning and importance of quality human data. Edwin talks about why he bootstrapped Surge instead of raising venture funds, the importance of scalable oversight in producing quality data, and the work Surge is doing to standardize human evals. Plus, we get Edwin's take on what Meta's investment into Scale AI means for Surge, as well as whether or not he thinks an underdog can catch up with OpenAI, Anthropic, and other dominant industry players. Sign up for new podcasts every week. Email feedback to show@no-priors.com Follow us on Twitter: @NoPriorsPod | @Saranormous | @EladGil | @echen | @HelloSurgeAI Chapters: 00:00 – Edwin Chen Introduction 00:41 – Overview of SurgeAI 02:28 – Why SurgeAI Bootstrapped Instead of Raising Funds 07:59 – Explaining SurgeAI's Product 09:39 – Differentiating SurgeAI from Competitors 11:27 – Measuring the Quality of SurgeAI's Output 12:25 – Role of Scalable Oversight at SurgeAI 14:02 – Challenges of Building Rich RL Environments 16:39 – Predicting Future Needs for Training AI Models 17:29 – Role of Humans in Data Generation 21:27 – Importance of Human Evaluation for Quality Data 22:51 – SurgeAI's Work Toward Standardization of Human Evals 23:37 – What the Meta/ScaleAI Deal Means for SurgeAI 24:35 – Edwin's Underdog Pick to Catch Up to Big AI Companies 24:50 – The Future Frontier Model Landscape 26:25 – Future Directions for SurgeAI 29:29 – What Does High Quality Data Mean? 32:26 – Conclusion
This week on The Beat, CTSNet Editor-in-Chief Joel Dunning speaks with CTSNet Senior Editor Dr. Sameh Said, Chief of the Division of Pediatric and Adult Congenital Cardiac Surgery at Maria Fareri Children's Hospital, Professor of Surgery and Pediatrics at the New York Medical College, and Consultant Cardiac Surgeon at King Faisal Specialist Hospital and Research Center about performing the first successful ex utero intrapartum treatment (EXIT)-to-open atrial septectomy-to-rapid stage I Norwood palliation in a neonate with hypoplastic left heart syndrome and intact interatrial septum. Chapters 00:00 Intro 03:13 JANS 1, Cardiac Transplant 09:04 JANS 2, Lung Transplant 10:19 JANS 3, Cardiac Transplant 11:08 JANS 4, Lung Cancer 13:01 JANS 5, Thoracic 15:44 Video 1, Congenital Cardiac 17:53 Video 2, Cardiac 19:49 Video 3, Cardiac 21:50 Dr. Said Interview, EXIT Procedure 37:28 Upcoming Events 39:32 Closing They discuss the surgical steps involved in this groundbreaking procedure, including specific details about the surgery, the preparation undertaken prior to the operation, and the key factors that contributed to its success. Additionally, they covered the challenges encountered during this first successful EXIT procedure case, as well as the standard management practices for these cases at medical centers, such as fetal balloon atrial septostomy, along with postnatal transcatheter, surgical, or hybrid interventions and their associated surgical risks. Furthermore, they address the broader challenges faced when operating on patients with hypoplastic left heart syndrome, including the differences between restrictive atrial septum and intact atrial septum. Joel also highlights recent JANS articles on the current state and future directions of cardiac xenotransplantation, if age is a contraindication for lung transplantation in the elderly, a summary of the International Society for Heart and Lung Transplantation consensus conference on emerging understanding of antibodies and antibody-mediated rejection in heart transplantation, inflammatory diseases and risk of lung cancer among individuals who have never smoked, and active chest tube clearance added to an Enhanced Recovery After Cardiac Surgery (ERAS) program improves outcomes and reduces resource utilization. In addition, Joel explores a single incision mitral valve repair and LIMA-to-LAD bypass via a left anterior minithoracotomy, repair of post-infarction ventricular septal defect using a double patch sandwich technique, and reconstruction of the left trigone during the Commando procedure for invasive prosthetic aortic valve endocarditis. Before closing, Joel highlights upcoming events in CT surgery. JANS Items Mentioned 1.) Cardiac Xenotransplantation: Current State and Future Directions 2.) Lung Transplantation in the Elderly: Is Age a Contraindication? 3.) Summary of the International Society for Heart and Lung Transplantation Consensus Conference on Emerging Understanding of Antibodies and Antibody-Mediated Rejection in Heart Transplantation 4.) Inflammatory Diseases and Risk of Lung Cancer Among Individuals Who Have Never Smoked 5.) Active Chest Tube Clearance Added to an Enhanced Recovery After Cardiac Surgery (ERAS) Program Improves Outcomes and Reduces Resource Utilization CTSNET Content Mentioned 1.) Single Incision Mitral Valve Repair and LIMA-to-LAD Bypass via a Left Anterior Minithoracotomy 2.) Repair of Post-Infarction Ventricular Septal Defect Using a Double Patch Sandwich Technique 3.) Reconstruction of the Left Trigone During the Commando Procedure for Invasive Prosthetic Aortic Valve Endocarditis Other Items Mentioned 1.) Guest Editor Series: Coronary Arterial Anomalies—Pediatric and Adult Congenital 2.) Cardiac Surgical Arrest—An International Conversation Series 3.) Career Center 4.) CTSNet Events Calendar Disclaimer The information and views presented on CTSNet.org represent the views of the authors and contributors of the material and not of CTSNet. Please review our full disclaimer page here.
As an American living in the UK, Matthew Sherwood unpacks what Independence Day really means from across the pond—and what it reveals about the growing divide between the US and UK. From political chaos to economic stagnation, he explores why the two nations feel increasingly out of sync.The episode also dives into the rise of political disruptors like Nigel Farage and Elon Musk, before teasing what's next for the podcast: bold new formats and fresh perspectives.Timestamps00:00 - Independence Day Reflections03:37 - The Diverging Paths of the US and UK07:49 - Political Landscape and Economic Realities09:21 - New Formats and Future Directions
Episode 73 - Intergalactic BFR with Luke Hughes, PhD Summary In this episode, Johnny Owens and Dr. Luke Hughes discuss the applications of Blood Flow Restriction (BFR) in space and its potential to mitigate deconditioning in astronauts. They explore the physiological changes that occur in microgravity, the importance of exercise countermeasures, and the innovative research being conducted to understand the mechanisms behind BFR's effectiveness. The conversation also touches on the implications of BFR for bone health, clinical applications, and future research directions. Takeaways BFR is a promising tool for mitigating muscle and bone deconditioning in space. Fluid shifts in microgravity can lead to significant health issues for astronauts. BFR can enhance the effectiveness of low-intensity aerobic exercise. Research is ongoing to understand the mechanisms behind BFR's benefits for bone health. BFR protocols need to be personalized for different patient populations. The use of BFR in clinical settings shows potential for improving recovery outcomes. BFR can help prevent amputations in patients with severe vascular issues. Understanding the impact of pressure on blood flow is crucial for optimizing BFR protocols. BFR can be integrated into rehabilitation programs for various conditions. Future research will focus on the long-term effects of BFR in both space and clinical settings. Chapters 00:00 Introduction and Overview of Blood Flow Restriction (BFR) 05:38 Bed Rest Studies and Their Importance in Space Research 12:45 Physiological Effects of Microgravity on Astronauts 18:41 Current Exercise Countermeasures in Space Missions 24:04 Future Directions and Innovations in Space Exercise 24:33 Innovations in Exercise Devices for Space Missions 26:41 The Role of Blood Flow Restriction (BFR) in Space Exercise 29:20 First Experiments with BFR in Microgravity 30:37 Collaboration with SpaceX for In-Orbit Research 31:59 Developing Space-Compatible Exercise Devices 33:53 BFR Exercise in Space: A Historic Milestone 35:06 Exercise Protocols and Adjustments for Space Conditions 37:45 Initial Findings from BFR Experiments in Space 40:47 Exploring Fluid Shifts and BFR's Impact 43:33 Combining Aerobic Exercise with BFR for Enhanced Benefits 48:51 Future Directions in BFR Research and Applications 53:07 Exploring Bone Adaptation Mechanisms 55:37 Methodological Framework for Bone Research 59:30 Innovations in Bone Blood Flow Measurement 01:02:31 BFR Applications in Rehabilitation and Pain Management 01:05:17 Future Directions in BFR Research and Space Applications Podcast Intro Attribution Song: Legendary Music by: CreatorMix.com Video: https://youtu.be/_oaZzkn0bW4 Podcast Outro Attribution Song: Smoke Rising Music by: CreatorMix.com Video: https://youtu.be/_oaZzkn0bW4
On this episode of Trending in Education, Mike Palmer is joined by Elliot Felix, a returning guest, to discuss his new book, The Connected College: Leadership Strategies for Student Success. The book, releasing July 22nd, focuses on how higher education can become more agile, connected, and break down silos. Elliot Felix shares his mission of student success, drawing on his experience consulting with over 120 colleges and universities to improve student experiences through transformations in physical spaces, support services, and technology systems. He explains that his new book aims to provide an evidence-based playbook for higher education professionals to collaborate better for student success. Key Takeaways: Addressing Disconnections in Higher Ed: Felix identifies five key disconnections the book addresses, including a lack of belonging among students (only 65% feel they belong), the disconnect between courses and careers, and the prevalence of siloed structures within institutions. He illustrates this with an example of a university having both a "writing lab" and a "writing center" performing similar functions due to historical and structural reasons. The Connected College Vision: Felix envisions a future where colleges and universities are better connected, leading to students feeling a stronger connection to their institution, their coursework linking to careers, and increased collaboration both internally and with external partners like corporations and community groups. Defining Student Success: The conversation delves into the multifaceted definition of student success, acknowledging that it can be viewed through metrics like retention and graduation rates, student engagement and belonging, or the individual student's perspective of success. Felix suggests common ground for student success includes students finding their community, their academic and career path, their place, and a sense of purpose. Silo Busting Strategies: Felix highlights that silos are common in organizations, particularly in higher education, which is designed for durability. He attributes this to a lack of clear strategy beyond broad, anodyne statements, and legacy structures that simply have new functions "bolted on" rather than integrated. Tactics for breaking down silos include sharing data to create a common understanding of students. Forward-Thinking Universities: Examples of innovative approaches include university-industry partnerships driving economic and workforce development, such as Carnegie Mellon's robotics innovation center and Rowan University's expansion into health and wellness and advanced manufacturing. Other examples include Imperial College London's enterprise lab, the University of South Florida's focus on entrepreneurship, and Arizona State's "Work Plus Learn" program. Don't miss Elliot's new book, The Connected College: Leadership Strategies for Student Success, available July 22nd wherever you get your books. Subscribe to Trending in Ed so you never miss a conversation about leading the future of education in these transformative times. 00:00 Introduction and Guest Welcome 01:07 Elliot Felix's Background and Mission 02:26 The Connected College: Themes and Issues 06:28 Book Structure and Innovator Profiles 07:54 Defining Student Success 13:23 Silo Busting in Higher Education 17:14 AI and Future Trends in Higher Ed 20:36 The Importance of Combining Skills in Higher Education 21:06 Collaborative Spirit in Developing AI Policies 22:26 Navigating Political and Technological Disruptions 31:15 The Role of Higher Education in Economic Development 31:43 Innovative University-Industry Partnerships 33:08 Spotlighting Success Stories in Higher Education 35:49 Concluding Thoughts and Future Directions
Fill out this short listener survey to help us improve the show: https://forms.gle/bbcRiPTRwKoG2tJx8In this episode, Simon Eskildsen, co-founder and CEO of TurboPuffer, lays out a compelling vision for how AI-native infrastructure needs to evolve in an era where every application wants to connect massive amounts of context to large language models. He breaks down why traditional databases and even large context windows fall short—especially at scale—and why object-storage-native search is the inevitable next step. Drawing on his experience from Shopify and Readwise, Simon introduces the SCRAP framework to explain the limits of context stuffing and makes a clear case for why cost, recall, performance, and access control drive the need for smarter retrieval systems. From practical lessons in building highly reliable infra to hard technical problems in vector indexing, this conversation distills the future of AI infra into first principles—with clarity and depth. [0:00] Intro[0:49] The Evolution of AI Context Windows[2:32] Challenges in AI Data Integration[3:56] SCRAP: Scale, Cost, Recall, ACLs, and Performance[9:21] The Rise of Object-Oriented Storage[16:47] Turbo Puffer Use Cases[22:32] Challenges in Vector Search[27:02] Challenges in Query Planning and Data Filtering[27:53] Focusing on Core Problems and Simplicity[28:28] Customer Feedback and Future Directions[29:11] Reliability and Simplicity in Design[30:39] Evaluating Embedding Models and Search Performance[32:17] The Role of Vectors in Search Engines[34:16] Balancing Focus and Expansion[35:57] AI Infrastructure and Market Trends[38:36] The Future of Memory in AI[43:01] Table Stakes for AI in SaaS Applications[45:55] Multimodal Data and Market Observations[46:57] Quickfire With your co-hosts: @jacobeffron - Partner at Redpoint, Former PM Flatiron Health @patrickachase - Partner at Redpoint, Former ML Engineer LinkedIn @ericabrescia - Former COO Github, Founder Bitnami (acq'd by VMWare) @jordan_segall - Partner at Redpoint
After nearly a decade of podcasting, Nick and Tyler hit record on a candid, unscripted conversation about burnout, direction, and the deeper purpose behind The Modern Craftsman. This episode pulls back the curtain on their evolving goals, the emotional toll of running a business, and the pressures of staying relevant in a saturated market. From questioning what growth really means to re-centering the show on meaningful conversations—not metrics—this is a raw, honest reset that long-time listeners won't want to miss. Show Notes: Pause and Reflection on the Podcast (0:00) Sponsor Acknowledgements and Podcast Content (1:59) Evaluating Podcast Content and Guest Selection (4:38) Exploring Broader Topics and Guest Insights (18:30) Balancing Personal and Professional Growth (20:47) Navigating Emotional and Business Challenges (24:34) Engaging with Listeners and Future Directions (1:04:36) Video Version: https://youtu.be/tISDDZMj6fU Partners: Andersen Windows Buildertrend Harnish Workwear Use code H1025 and get 10% off their H-label gear The Modern Craftsman: linktr.ee/moderncraftsmanpodcast Find Our Hosts: Nick Schiffer Tyler Grace Podcast Produced By: Motif Media
In this episode of the Boost Your Biology podcast, Lucas Aoun interviews Dr. Jonathann Kuo, an expert in longevity science and the founder of Extension Health. They discuss Dr. Kuo's journey into regenerative medicine, the shift in pain management practices, the significance of the vagus nerve, and innovative therapies such as plasmapheresis and hyperbaric therapy. The conversation also covers the role of peptides in health optimization, advancements in weight loss therapies, and the future of stem cell research. Dr. Kuo shares insights on the importance of personalized medicine and the exciting developments in the field of longevity.Relevant links:Dr Jonathan Kuo's IG: https://www.instagram.com/dr.kuo/ Check Out My Website For Coaching, Recommended Products and Much More:https://www.boostyourbiology.com/ Disclaimer:The information provided in this podcast episode is for entertainment purposes and is NOT MEDICAL ADVICE. The products presented and discussed in this podcast are explicitly only relevant to those who reside in the US. The statements and discussions held within this episode, are NOT approved by the TGA. If you have any questions about your health, contact a medical professional. This content is strictly the opinions of Lucas Aoun and is for informational and entertainment purposes only. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All viewers of this content are advised to consult with their doctors or qualified health professionals regarding specific health questions. Neither Lucas Aoun nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this content. All consumers of this content especially taking prescription or over-the-counter medications should consult their physician before beginning any nutritional, supplement or lifestyle program.Chapters00:00 Introduction to Longevity Science02:54 Journey into Regenerative Medicine05:50 The Shift in Pain Management08:51 Understanding the Vagus Nerve11:45 Neuro Reset Procedure Explained14:24 Peptides and Their Role in Health17:16 Advancements in Weight Loss Therapies20:05 The Future of Stem Cell Research22:53 Plasmapheresis and Its Benefits25:53 Hyperbaric Therapy Insights28:43 Innovations in Peptide Delivery31:32 The Role of AI in Medicine34:25 Future Directions for Extension Health Hosted on Acast. See acast.com/privacy for more information.
In this episode of A Shot in the Arm podcast, host Ben Plumley is joined by Professor Heidi Larson, co-founder of the Global Listening Project, and Dr. Nduku Kilonzo, managing director of Yemaya Health Advisory. Recorded in during IAS 2025 in Kigali, Rwanda, the discussion centers on the essential contributions of faith leaders to global health, particularly in engaging communities and influencing public health decisions. The episode explores findings from the Global Listening Project's studies in Kenya and Nigeria, highlighting the deep trust communities place in faith leaders and the necessity of including them in health initiatives. The conversation emphasizes the need for health professionals to rethink their engagement strategies with faith communities, the role of digital technologies, and the importance of co-creating health solutions with faith leaders. 00:00 Introduction and Welcome 00:17 Meet the Guests: Professor Heidi Larson and Dr. Nduku Kilonzo 00:35 The Role of Faith Leaders in Global Health 02:20 Insights from the Global Listening Project 03:54 Challenges and Opportunities in Engaging Faith Leaders 05:17 Deep Listening Techniques and Findings 07:49 Faith Leaders' Perspectives on Health Issues 09:53 The Importance of Trust and Engagement 19:11 Digital Technologies and Faith Communities 24:27 Future Directions and Final Thoughts 28:30 Closing Remarks and Thanks
Are your current stroke interventions in line with the latest clinical data? Dr. Blaise Baxter, interventional radiologist at Sutter Health, and Dr. Jim Milburn, interventional neuroradiologist at the Ochsner Health, join host Dr. Michael Barraza to discuss the latest advancements in stroke interventions. --- This podcast is supported by: Imperative Carehttps://imperativecare.com/stroke/zoom-stroke-solution/ --- SYNPOSIS The episode begins with a discussion on the different pathways to becoming a neurointerventionalist, emphasizing why interventional radiologists are uniquely equipped for this transition. They dive into cutting-edge stroke interventions, sharing key takeaways from major trials on large core and medium vessel occlusions. Dr. Baxter and Dr. Milburn highlight the HERMES trial, which showed that endovascular thrombectomy led to beneficial effects on patients with anterior circulation occlusion. They then cover the BAOCHE trial, which showed better functional outcomes with thrombectomy over medical therapy. Milburn and Baxter also share their perspectives on the shifting role of perfusion imaging and why the field may be moving beyond it. To close the discussion, the doctors underscore the powerful impact of rehabilitation in driving patient recovery, and stress the ongoing need for innovation and improved training in the field of neurointerventional radiology. --- TIMESTAMPS 00:00 - Introduction06:18 - Training and Certification in Neurointervention13:11- Large Core Trials and Their Impact19:42 - CT Perfusion and Treatment Decisions29:45 - Understanding Stroke Scale Scores and ICAD30:31 - Thrombectomy Trials and Treatment Strategies34:48 - Challenges in Randomizing Patients for Trials44:25 - Advancements in Robotics and Stroke Treatment51:37 - Future Directions in Stroke Rehabilitation53:11 - Global Thrombectomy Adoption and Training --- RESOURCES Hermes trial: Goyal M, Menon BK, van Zwam WH, et al. Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials. Lancet. 2016;387(10029):1723-1731. doi:10.1016/S0140-6736(16)00163-X BAOCH trial: Jovin TG, Li C, Wu L, et al. Trial of Thrombectomy 6 to 24 Hours after Stroke Due to Basilar-Artery Occlusion. N Engl J Med. 2022;387(15):1373-1384. doi:10.1056/NEJMoa2207576
In this episode of the Diabetes Innovators Series, the conversation explores the evolution of diabetes treatment, the challenges faced in managing diabetes today, and the future of diabetes research. Zan, an endocrinologist and former FDA executive and Founder and executive chairman of Kinexum, shares insights from his career, including the historical context of diabetes management, the importance of A1C as a marker, and the potential of new treatments like GLP-1 agonists. The discussion also touches on the concept of meta-abesity, the shared root causes of chronic diseases, and the need for a focus on health span rather than just lifespan. Chapters 00:00 Introduction to Diabetes Innovation Series 03:06 Zan's Journey in Diabetes Research 06:05 Transforming Diabetes Treatment: A Historical Perspective 09:00 The Evolution of Diabetes Management Tools 11:42 Challenges in Diabetes Management Today 14:41 The Future of Diabetes Treatment: Aiming for a Cure 17:57 Understanding the Drug Approval Process 20:32 Meta-Abesity: A New Perspective on Chronic Diseases 23:48 Innovations in Longevity and Health Span 26:27 The Role of GLP-1 Agonists in Diabetes Management 29:29 Future Directions in Diabetes Research 32:29 Memorable Moments in Drug Proposals 35:37 Conclusion and Future Collaborations Resources: Kinexum Zan Fleming
In this episode, the hosts discuss 'Jump' the long-awaited comeback of BLACKPINK after three years! They dive into the visuals, production choices, the impact of AI in music videos and speculate on the future direction of BLACKPINK as they approach their 10-year anniversary. They also share Hit Replays From TWICE, BABYMONSTER & Yung Raja x Jay ParkJoin the Kpopcast Slack: https://join.slack.com/t/kpopcast/shared_invite/zt-93kzxcv6-YNej2QkyY6vaPnhEQJxk0AChip in for editing: https://ko-fi.com/thekpopcast HIT REPLAYS:BABYMONSTER - ‘HOT SAUCE' M/V https://youtu.be/xn8mQqz2xmM?si=kPledLm0LbCJBi98 Yung Raja x Jay Park ‘missed call' https://youtu.be/spDokk5zl-0?si=7XpjEOuYL5-S6E2v BATTITUDE (NAYEON, JEONGYEON, MOMO, MINA) https://youtu.be/TOic7n-CDd4?si=aTfzQTwPr0sMl19p Chapters00:00 Introduction to K-Pop Hits00:29 BABYMONSTER03:33 Jay Park x Young Raja05:56 TWICE's New Era and Attitude10:08 BLACKPINK Deep Dive11:49 Live Reaction to BLACKPINK's 'Jump'17:36 Comparative Discussion: 'Jump' vs. Previous Releases22:40 Audio Quality and Production Choices28:40 The Impact of AI on Authenticity34:20 Rushed Releases and Quality Concerns38:13 Future Directions for Blackpink Hosted on Acast. See acast.com/privacy for more information.
In this episode, we explore the intersection of ovarian health, menopause, and AI technology with Kiran, the founder of TimelessBioTech. The conversation delves into the importance of ovarian longevity for women's health, the predictive tools being developed to forecast menopause timing, and the various interventions that can support ovarian health. Kiran shares insights on hormonal balance, the role of lifestyle factors, and the future of personalized health strategies for women. The discussion emphasizes the need for targeted solutions and the potential for AI to revolutionize women's health care.Timeless Biotech WebsiteKiran's email for investors, clinics, and companies looking to invest in or work with Timeless: Kiiran@timelessbiotech.comThis episode is brought to you by OneSkin, the longevity scientists behind the first topical peptide scientifically proven to reverse skin aging—now bringing their expertise to your scalp. If you care about aging well, you can't ignore your hair. The health of your scalp directly impacts the strength, thickness, and lifespan of every strand. That's why OneSkin created their new OS-01 HAIR, the first scalp serum powered by a longevity peptide designed to optimize follicle health, balance the scalp, and extend the healthspan of your hair follicles. In their clinical study, OS-01 HAIR showed significant improvements in hair density, thickness, and overall scalp health—all by targeting follicle aging at the root. I've been using it myself and I'm genuinely impressed. It's lightweight, fragrance-free, and backed by science—not fluff. If you're serious about keeping your hair vibrant and resilient as you age, I highly recommend giving OneSkin's OS-01 HAIR a try. Head to oneskin.co/KAYLA for 15% off your order. About KiranKiran Kumar is the Founder & CEO of Timeless Biotech, an early-stage ovarian longevity company that has prototyped the first-ever time-to-menopause predictor and ovarian age clock. Kiran is a Biotechnology Bioengineer from UC San Diego, and has contributed to research in ML-powered diagnostics.Kiran has worked in numerous longevity and wellness startups such as FOXO Technologies, OneSkin, and Timeline where she authored. research-backed contentKiran's work sits at the intersection of Physiology, AI, and Longevity.Chapters00:00 Introduction to Ovarian Longevity and AI Solutions02:44 The Importance of Ovarian Health in Longevity05:38 Understanding Menopause and Ovarian Aging08:48 Predictive Tools for Menopause Timing11:32 Interventions for Ovarian Longevity14:31 The Role of Hormones in Ovarian Health17:25 Innovative Approaches to Hormonal Balance20:14 The Future of Ovarian Health Technologies22:58 Personalized Health Strategies for Women25:31 Conclusion and Future Directions
Send us a textIn this episode of Causes or Cures, Dr. Eeks chats with immunology expert Dr. Maziar “Maz” Divangahi about how a fiber found in mushrooms may help us beat the flu, and he introduces us to the concept of disease tolerance. What We'll CoverBeta-Glucan 101What it is: a natural fiber in the outer wall of fungi (think mushrooms).Why it matters: mounting evidence says it can help you fight off the flu by improving something called disease tolerance. Two Immune PlaybooksHost Resistance: the classic “seek and destroy” tactic.Disease Tolerance: a quieter, damage-control strategy our bodies use to stay functional even when a pathogen sticks around.Dr. Maz will unpack how beta-glucan may tilt the balance toward disease tolerance.From TB Labs to Flu ResearchInsights from Dr. Maz's tuberculosis studies that set the stage for his beta-glucan–flu work.Early data on how this fungal fiber might boost flu-specific disease tolerance.Should We Eat More Mushrooms or Supplement?Practical tips and caveats on dietary vs. supplemental beta-glucan.What the current evidence actually supports.Beyond Infections: Beta-Glucan in Cancer TrialsSnapshot of ongoing studies in breast and bladder cancer.Why disease tolerance is a hot oncology frontier.Future Directions & Take-Home PointsWhere Dr. Maz's research is headed next.Simple, science-backed actions listeners can try today.Listen If You've Ever Wondered…Why some people sail through the flu while others end up in the ER.Whether “disease tolerance” might rewrite how we tackle pandemics.If tossing extra shiitakes into your stir-fry can really make a difference.Dr. Maziar (Maz) Divangahi is a Professor of Medicine at McGill University. He is the Associate Director of the Meakins-Christie Laboratories and the Associate Director of the McGill Interna onal TB Centre. He is an internationally recognized pulmonary immunologist and the overarching focus of his research program is to inves gate the regulatory mechanisms involved in host resistance and disease tolerance against major pulmonary bacterial (Mycobacterium tuberculosis) and viral (influenza virus and SARS-CoV2) pathogens. He is currently inves ga ng how to harness the power of innate memory response (Trained Immunity) in vaccine development. Throughout his career, he has been a prolifera ve inves gator publishing in outstanding journals and received numerous awards, including a CIHR New Inves gator Award, FRQS Award, and the CIHR Founda on grant. His scholarly work has been recognized by elec on to the Royal Society of Canada. He is currently holding the Strauss Chair in Respiratory Diseases. You can contact Dr. Eeks at bloomingwellness.com.Follow Eeks on Instagram here.Or Facebook here.Or X.On Youtube.Or TikTok.SUBSCRIBE to her monthly newsletter here! (Now featuring interviews with top experts on health you care about!)Support the show
Sensorimotor Dysfunction & the Cervical Spine: What Clinicians Miss After Concussion | Dr. Julia Treleaven Part I
Proudly sponsored by PyMC Labs, the Bayesian Consultancy. Book a call, or get in touch!Intro to Bayes Course (first 2 lessons free)Advanced Regression Course (first 2 lessons free)Our theme music is « Good Bayesian », by Baba Brinkman (feat MC Lars and Mega Ran). Check out his awesome work!Visit our Patreon page to unlock exclusive Bayesian swag ;)Takeaways:INLA is a fast, deterministic method for Bayesian inference.INLA is particularly useful for large datasets and complex models.The R INLA package is widely used for implementing INLA methodology.INLA has been applied in various fields, including epidemiology and air quality control.Computational challenges in INLA are minimal compared to MCMC methods.The Smart Gradient method enhances the efficiency of INLA.INLA can handle various likelihoods, not just Gaussian.SPDs allow for more efficient computations in spatial modeling.The new INLA methodology scales better for large datasets, especially in medical imaging.Priors in Bayesian models can significantly impact the results and should be chosen carefully.Penalized complexity priors (PC priors) help prevent overfitting in models.Understanding the underlying mathematics of priors is crucial for effective modeling.The integration of GPUs in computational methods is a key future direction for INLA.The development of new sparse solvers is essential for handling larger models efficiently.Chapters:06:06 Understanding INLA: A Comparison with MCMC08:46 Applications of INLA in Real-World Scenarios11:58 Latent Gaussian Models and Their Importance15:12 Impactful Applications of INLA in Health and Environment18:09 Computational Challenges and Solutions in INLA21:06 Stochastic Partial Differential Equations in Spatial Modeling23:55 Future Directions and Innovations in INLA39:51 Exploring Stochastic Differential Equations43:02 Advancements in INLA Methodology50:40 Getting Started with INLA56:25 Understanding Priors in Bayesian ModelsThank you to my Patrons for making this episode possible!Yusuke Saito, Avi Bryant, Ero Carrera, Giuliano Cruz, James Wade, Tradd Salvo, William Benton, James Ahloy, Robin Taylor,, Chad
In this episode of the Diabetes Innovators Series, Rob interviews Dr. Anath Shalev discussing the recent advancements in TIXiMed's TIX100, an oral therapy for type 1 diabetes. The conversation covers the successful completion of a phase one study, the implications of the results, and the potential impact of TIX100 on diabetes management. Dr. Shalev emphasizes the importance of addressing beta cell dysfunction and the exciting metabolic signals observed during the study. The discussion also touches on the future directions for TIX100 and its role in improving the lives of diabetes patients. Chapters Chapters 00:00 Introduction to TixiMed and TIX100 01:16 Phase One Study Results and Implications 05:22 Metabolic Signals and Future Studies 08:11 The Role of TIX100 in Diabetes Management 09:47 Future Directions and Patient Impact Resources: TIXiMED Dr. Anath Shalev