POPULARITY
How do you effectively treat your bladder cancer population with an insufficient supply of BCG? Dr. Amy Luckenbaugh, a urologic oncologist at Vanderbilt University Medical Center, joins host Dr. Ruchika Talwar to highlight challenges and solutions to managing bladder cancer amidst ongoing BCG shortages. --- This podcast is supported by an educational grant from UroGen Pharma. --- SYNPOSIS Dr. Luckenbaugh and Dr. Talwar delve into the history and significance of BCG in bladder cancer treatment, exploring the reasons behind the shortages and discussing various coping strategies, including split dosing and alternative intravesical therapies like gemcitabine, docetaxel, and the new mitomycin hydrogel. The conversation also covers emerging treatments for high-risk patients, the role of radical cystectomy, and the importance of standardization and innovation in dealing with medication shortages. Dr. Luckenbaugh highlights the importance of patient quality of life, cost considerations, and the need for resilient pharmaceutical supply chains. --- TIMESTAMPS 00:00 - Introduction01:56 - History and Importance of BCG in Bladder Cancer03:21 - Challenges and Shortages of BCG06:36 - Managing BCG Shortages in Clinical Practice12:33 - New Alternatives and Treatments for Bladder Cancer23:28 - The Role of Cystectomy in Bladder Cancer Treatment26:12 - Future Directions and Final Thoughts --- RESOURCES BCG Shortage AUA Recommendations:https://www.auanet.org/about-us/bcg-shortage-info Reduced-dose bacillus Calmette-Guérin (BCG) in an era of BCG shortage: real-world experience from a tertiary cancer centre: https://pmc.ncbi.nlm.nih.gov/articles/PMC11951178/ Bladder Cancer Advocacy Network (BCAN):https://bcan.org/ Primary Chemoablation of Recurrent Low-Grade Intermediate-Risk Nonmuscle-Invasive Bladder Cancer With UGN-102: A Single-Arm, Open-Label, Phase 3 Trial (ENVISION)https://pubmed.ncbi.nlm.nih.gov/39446087/b FDA Approves Intravesical Mitomycin in Non–Muscle-Invasive Bladder Cancer:https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-mitomycin-intravesical-solution-recurrent-low-grade-intermediate-risk-non-muscle TAR-200 - SunRISe-3 Study:https://www.jnjmedicalconnect.com/products/tar-200/medical-content/tar-200-sunrise-3-study First results from TAR-200 - SunRISe-1 Study:https://www.jnj.com/media-center/press-releases/johnson-johnsons-tar-200-monotherapy-achieves-high-disease-free-survival-of-more-than-80-percent-in-bcg-unresponsive-high-risk-papillary-nmibcN-803 Plus BCG Treatment for BCG-Naïve or -Unresponsive Non-Muscle Invasive Bladder Cancer: A Plain Language Review:https://pmc.ncbi.nlm.nih.gov/articles/PMC11524197/
Summary In this truncated replay from a session at the 2025 SF Derm Annual Conference, Dr. Daniel Butler, Dr. Lawrence Eichenfield, Dr. Jason Hawkes, Dr. Shyam Joshi, and Dr. Bob Geng discuss the workup for chronic urticaria, focusing on testing approaches, the role of biomarkers, and insights into immune deficiencies. These panelists share their experiences and guidelines, emphasizing the importance of symptomatic management and the variability of lab results in clinical practice. Takeaways - Initial workup for chronic urticaria often does not require specific testing. - Testing may be justified if standard treatments fail. - International guidelines differ from US guidelines regarding testing. - Biomarkers currently available are not reliable for treatment decisions. - Symptomatic management should be prioritized over extensive testing. - Clinical trials show variability in lab results over time. - Excessive lab testing can lead to confusion and unnecessary anxiety for patients. - Understanding patient history is crucial in diagnosing immune deficiencies. - The role of family history is significant in identifying X-linked conditions. - Collaboration among dermatologists is essential for advancing treatment approaches. Chapters 00:00 - Introduction to Chronic Urticaria Workup 02:47 - Testing Approaches and Guidelines for Chronic Urticaria 05:41 - The Role of Biomarkers in Treatment Decisions 08:16 - Clinical Insights on Immune Deficiencies 11:14 - Variability in Lab Results and Clinical Trials 14:07 - Conclusion and Future Directions in Dermatology
In this episode of the Radical Health Rebel podcast, Leigh Brandon interviews Ben O'Loghlin, an expert in the Alexander Technique. They discuss Ben's personal journey with chronic pain and how he discovered the Alexander Technique as a solution. The conversation delves into the role of the brain in muscle tension, the importance of active engagement in healing, and the misconceptions surrounding chronic pain. Ben emphasizes the significance of self-management and the mind-body connection in pain perception. They also explore how the Alexander Technique can benefit musicians by enhancing their performance through improved posture and relaxation. The episode concludes with Ben sharing his future plans for an online course and innovative approaches to teaching the Alexander Technique.Chapters00:00 The Journey to Alexander Technique03:03 Understanding the Alexander Technique05:58 Active vs Passive Treatments08:46 Challenging Age-Related Pain Myths11:40 Misconceptions About Back Pain14:44 The Role of the Medical Model17:38 Exploring Modalities for Pain Relief20:51 The Mind-Body Connection in Pain23:46 Navigating Automatic and Voluntary Systems33:43 Understanding Automatic Postural Control40:39 The Role of Directions in Alexander Technique47:42 Personal Transformations Through Alexander Technique54:28 Posture, Movement, and Performance in Musicians01:00:37 Engineering Perspective on Body Mechanics01:04:18 Future Directions and Innovations in Alexander TechniqueYou can find Ben @:https://www.backrepublic.comhttps://youtube.com/@benologhlinhttps://facebook.com/ben.ologhlinSend us a textSupport the showDon't forget to leave a Rating for the podcast!You can find Leigh @: Leigh's website - https://www.bodychek.co.uk/ Chronic Pain Breakthrough Blueprint - https://www.bodychek.co.uk/freepainguide/ Leigh's courses: StickAbility - https://stickabilitycourse.com/ Mastering Client Transformation (professional course) - https://www.functionaldiagnosticnutrition.com/mastering-client-transformation/
Guest: Robert Johnson MD DMD https://duotoothpaste.com/?srsltid=AfmBOorY6XC93IxhnT-RogfUks5RkbcpCMvUQXAjWtLvYFdImX4MazTW Host: Serv Wahan MD DMD https://www.drwahan.com/ keywords Duo Toothpaste, Hydroxyapatite, Fluoride, Oral Health, Sustainable Dental Care, Innovative Toothpaste, Dental Products, SLS-Free, Oral Hygiene, Dental Technology, fluoride, fluoride-free, nano-hydroxyapatite, remineralization, tablet toothpaste, Dr. Wahan, Serv Wahan, Robert Johnson MD DMD, Fluoride-free toothpaste summary In this conversation, Dr. Bobby Johnson discusses the innovative Duo Toothpaste, a tablet-based toothpaste developed with a focus on sustainability and oral health. He shares insights into the concept behind Duo, the science of nano-hydroxyapatite as an alternative to fluoride, and the benefits of using SLS-free products. The discussion also covers the business journey of Duo and the importance of customer retention in the dental care market. takeaways Duo Toothpaste is a tablet-based product that aims to innovate oral hygiene. The idea for Duo was born from a desire to make brushing teeth exciting. Nano-hydroxyapatite is an effective alternative to fluoride for remineralizing teeth. Duo Toothpaste is packaged in a recyclable glass jar, reducing plastic waste. The product is SLS-free, making it gentler on the oral microbiome. Duo offers different tablet types, including those with added caffeine and vitamins. The company focuses on sustainability and reducing carbon footprint. Customer retention is high, indicating satisfaction with the product. Duo Toothpaste is safe for children, addressing concerns about fluoride ingestion. The conversation highlights the importance of ongoing research in dental health. titles Revolutionizing Oral Care with Duo Toothpaste The Science Behind Duo Toothpaste Sound Bites "Duo is a tablet toothpaste." "Fluoride is a hot topic." "SLS is an irritant." Chapters 00:00Introduction to Duo Toothpaste 02:57The Concept Behind Duo Toothpaste 04:49Fluoride vs. Hydroxyapatite: A Deep Dive 05:50The Science of Nano-Hydroxyapatite 08:40Benefits of Nano-Hydroxyapatite Over Fluoride 09:12Understanding Tooth Sensitivity and Treatment Options 11:32The Role of Surfactants in Oral Care 13:36Innovations in Toothpaste: From Tablets to Foams 15:54The Benefits of Caffeine and Vitamins in Toothpaste 18:21Fluoride vs. Nano-Hydroxyapatite: A New Perspective 21:21Business Insights: Launching a Dental Product 23:22Final Thoughts and Future Directions
In the return episode of Delta Dispatches, host Simone Maloz is joined by Dr. Alisha Renfro and Steve Cochran to discuss Louisiana's coast, its people, wildlife and jobs, and why restoring it matters. Today we explore the ecological, economic, and community significance of the Louisiana's coast and the challenges and implications following the state's decision not to move forward with the Mid-Barataria Sediment Diversion. 01:47 Importance of Louisiana's Coast 02:28 Milestones and Successes in Coastal Restoration 14:08 The Role of the Mississippi River 19:43 Introduction of Steve Cochran 24:09 The Importance of Louisiana's Coastal Program 27:09 Challenges and Changes in Coastal Restoration 29:23 Implications of the Mid-Barataria Decision 37:26 Reflections and Future Directions
SummaryIn this conversation, Jennifer Darling and Warren Olson discuss the evolution of fire protection, the importance of continuing education, and the role of mentorship in the fire service. They explore Warren's extensive career, his involvement with the NFPA, and the challenges faced in fire safety regulations. The discussion highlights the significance of teaching and the impact of major fire incidents on current safety practices.takeawaysMICE aims to simplify continuing education for providers and administrators.Warren Olson has over 50 years of experience in fire protection.He emphasizes the importance of mentorship in the fire service.Generational changes have improved firefighter health and safety.Teaching has been a passion for Warren throughout his career.NFPA technical committees play a crucial role in developing fire safety codes.Challenges in fire safety regulations are influenced by special interest groups.Lessons from past fire incidents shape current safety practices.The pendulum of fire safety regulations swings with public perception.Warren's journey reflects the importance of continuous learning in fire protection.Sound Bites"I've been doing this a long time.""Teaching gives me the greatest joy.""The codes are being chipped away."Chapters00:00Introduction to MICE and TrackMyCE.io01:25Warren Olson's Journey in Fire Protection05:55Career Progression and Experiences in Fire Service11:52Generational Changes in Fire Service17:52The Importance of Teaching and Mentorship23:52Involvement with NFPA Technical Committees29:54Challenges in Fire Safety Regulations35:56Lessons from Major Fire Incidents41:33Reflections on Fire Safety and Future Directions
In this episode of Psychedelics Today, Joe Moore sits down with Chad Charles — educator, mentor, and practitioner specializing in 5-MeO-DMT therapy. Chad shares his decade-long journey working with 5-MeO-DMT, emphasizing the importance of: Practitioner training and mentorship Personalized, therapeutic alliances The nuanced understanding of dissociative states Ethics in standardized clinical dosing A trauma-informed approach to psychedelic care He also introduces his upcoming research project, analyzing 500+ one-on-one sessions to illuminate best practices and ethical frameworks in the 5-MeO-DMT space. This is a must-listen for anyone passionate about harm reduction, responsible facilitation, and the future of psychedelic therapy.
When it comes to spinal oncology, no single specialty holds all the answers. In this episode of the BackTable Podcast, host Dr. Alexa Levey, an interventional radiologist from Yale School of Medicine, is joined by Dr. Mark Amsbaugh, a radiation oncologist, and Dr. Ran Lador, an orthopedic spine surgeon, both from the University of Texas McGovern Medical School. The discussion explores complexities and innovations in the multidisciplinary treatment of spinal tumors. --- SYNPOSIS Dr. Ambsbaugh and Dr. Lador highlight their cohesive, patient-centered approach at Memorial Hermann, integrating various specialties including surgery, radiation oncology, and interventional radiology. The episode emphasizes the importance of collaborative techniques, advances in minimally invasive surgeries, the role of stereotactic radiosurgery, and the critical nature of personalized patient care in improving outcomes for patients with spinal tumors. --- TIMESTAMPS 00:00 - Introduction01:20 - Multidisciplinary Approach to Spinal Tumors at Memorial Hermann10:22 - Surgical Techniques and Timing for Radiation Treatments 12:25 - Approach to Collaborative Treatment Planning25:45 - Connection Between Surgical and Radiation Oncology in Patient Care31:08 - The Role of Vertebral Augmentation in Spinal Oncology40:08 - Multimodal Pain Management Strategies47:35 - Thoughts on Future Directions in Spinal Oncology and Conclusion --- RESOURCES Dr. Mark Amsbaugh, MDhttps://med.uth.edu/neurosciences/dr-mark-j-amsbaugh-md/ Dr. Ran Lador, MDhttps://med.uth.edu/ortho/2022/11/02/ran-lador-md/ Dr. Alexa Levey, MDhttps://medicine.yale.edu/profile/alexa-levey/
In this episode of the PFC Podcast, host Dennis interviews Jeff Ory, a recent medical graduate and former infantryman, discussing the critical topic of tension pneumothorax and the techniques for needle decompression. They explore the historical data on tension pneumothorax mortality, the effectiveness of different decompression sites, and the risks associated with the procedure. The conversation also delves into the importance of ongoing training for medics, the debate over who should be trained in needle decompression, and the best practices for chest tube placement. The episode concludes with thoughts on the future of trauma care and the need for continuous improvement in medical training.TakeawaysTension pneumothorax is primarily a blood flow issue, not a respiratory one.The fifth intercostal space is often preferred for needle decompression due to safety and accuracy.Hubbing a needle during decompression poses significant risks.Many patients do not show objective improvement after needle decompression.Training in emergency procedures must be continuous to maintain skills.The placement of chest tubes is debated, with various opinions on the best approach.Most patients with pneumothorax also have other injuries that complicate treatment.Emergency procedures should be simplified for better retention and execution.The risk of injury from needle decompression is a significant concern.Emergent decompression is crucial for patient survival in trauma situations.Chapters00:00 Introduction to the Podcast and Guest01:08 Understanding Tension Pneumothorax07:04 Needle Decompression Techniques and Efficacy12:20 Risks and Complications of Needle Decompression20:03 Training and Skill Retention in Emergency Medicine30:44 Debate on Needle Decompression in Military Training39:04 Chest Tube Placement and Techniques49:22 Conclusion and Future Directions in Trauma CareThank you to Delta Development Team for in part, sponsoring this podcast.deltadevteam.comFor more content, go to www.prolongedfieldcare.orgConsider supporting us: patreon.com/ProlongedFieldCareCollective or www.lobocoffeeco.com/product-page/prolonged-field-care
Vitamin A5 is a fascinating "new" vitamin that acts as a vital key in your body. It helps activate something called the Retinoid X Receptor (RXR), which is like a central control panel or "master switch" for many important functions. This crucial vitamin comes from certain foods, especially leafy green vegetables. Research suggests that many people in Western countries aren't consuming enough of these foods, leading to a potential Vitamin A5 deficiency. This lack could be a contributing factor to the rising rates of poor mental health and neurological issues. By making sure you get enough Vitamin A5 through your diet, you're essentially providing your body with the right tool to keep these vital systems running smoothly, offering a plausible explanation for why a diet rich in vegetables is so protective against many common diseases.Disclaimers"This video shares information for learning only and isn't medical advice." "The science on Vitamin A5 is still growing, and we need more studies in people to fully understand all its effects, especially on the brain.""Always talk to your doctor or a health expert before changing your diet or taking any new supplements, especially if you have health concerns or take medications." "This channel does not make money from videos and does not give medical advice."#VitaminA5 #BrainHealth #HealthyEating #MentalWellness #EatYourGreensBohn T, Rohn S, Böhm V, Despotovic M, de Lera AR, Krezel W, Kucuk O, Bánáti D, Rühl R. Vitamin A5: Evidence, Definitions, Gaps, and Future Directions. Nutrients. 2025; 17(14):2317. https://doi.org/10.3390/nu17142317Alchepharma,Ralph Turchiano,citation,research,study,Vitamin A5 benefits,new vitamin discovery,leafy greens brain,healthy diet mental health,RXR activation,retinoid X receptor,neurodegenerative disease prevention,cognitive function diet,what is Vitamin A5,natural brain boost,dietary supplements science,mental clarity food,immune system vitamin,cellular differentiation,chronic disease diet,carotenoids health,future of vitamins,9-cis-beta-carotene
Hodlbod brings a unique perspective, bridging the old and the new, with a focus on a healthier relationship between users and the digital world.Hodlbod on Nostr: https://primal.net/p/nprofile1qqsf03c2gsmx5ef4c9zmxvlew04gdh7u94afnknp33qvv3c94kvwxgsm3u0w6 His Book: https://building-nostr.coracle.social Coracle: https://coracle.socialFlotilla: https://flotilla.social/His other apps: https://stuff.coracle.social EPISODE: 170BLOCK: 907160PRICE: 858 sats per dollar(00:00:01) Tesla's Bitcoin Holdings and Opportunity Costs(00:01:11) Happy Bitcoin Friday(00:03:01) Guest Introduction: Hodlbod(00:04:20) Challenges of Streaming and Notifications(00:06:30) Decentralized Technology and Social Media(00:10:04) Push Notifications and Privacy Concerns(00:15:00) Reforming Technology and Social Media(00:20:00) Decentralization and Political Dynamics(00:25:00) Nostr's Adoption and Future Prospects(00:33:00) Nostr's Unique Protocol and Challenges(00:40:00) AI's Role in Development and Vibe Coding(00:50:00) Micro Apps vs. Holistic Experiences on Nostr(01:00:00) Social Media Addiction and User Experience(01:10:00) Group Chats and Community Building(01:20:00) Signal's Influence and Privacy Concerns(01:30:00) Monetization and Sustainability on Nostr(01:50:00) Nostr's Development and Future Directions(02:00:00) Book Release: Building NostrVideo: https://primal.net/citadelsupport dispatch: https://citadeldispatch.com/donate nostr live chat: https://citadeldispatch.com/stream odell nostr account: https://primal.net/odell dispatch nostr account: https://primal.net/citadel ten31 x account: https://x.com/ten31funds youtube: https://www.youtube.com/@CitadelDispatch podcast: https://serve.podhome.fm/CitadelDispatch stream sats to the show: https://www.fountain.fm/ rock the badge: https://citadeldispatch.com/shop learn more about me: https://odell.xyz
In this episode of Psychedelics Today, Joe Moore sits down with Alan Davis, Associate Professor at Ohio State University, to explore the evolving landscape of Ibogaine research and its therapeutic potential. Alan offers a deep dive into the Iboga Patient Survey, a groundbreaking initiative collecting real-world data on the safety and efficacy of Ibogaine—particularly for those struggling with substance use disorders and mental health challenges. The conversation sheds light on the need for rigorous, community-informed research that could pave the way toward FDA approval and increased access for patients, including veterans dealing with trauma. They also discuss the complexities of clinical trials, the tension between state and federal regulations, and the growing influence of corporate interests in psychedelic research. Alan emphasizes the importance of ethical transparency, community collaboration, and maintaining scientific integrity as the field grows. If you're curious about the intersection of psychedelic medicine, clinical research, and patient safety, this is a must-listen episode. Topics Covered 00:00 – Introduction and Guest Welcome 00:53 – Reflecting on COVID-19's Psychological Impact 01:29 – Introducing the Iboga Patient Survey 01:46 – History and Goals of Ibogaine Research 02:41 – Challenges in Conducting Clinical Trials 03:14 – Importance of Real-World Safety Data 06:55 – Personal Interest in Ibogaine 08:56 – Veterans and Trauma: A Personal Connection 10:53 – Reintegration and Emotional Processing 15:29 – Survey Participation and Accessibility 18:25 – Building Partnerships and Overcoming Challenges 21:06 – Ensuring Safety and Transparency 31:49 – Community and Academic Collaboration 33:06 – Survey Design and Future Research Directions 36:50 – Momentum in Psychedelic Research 37:48 – State vs. Federal Regulation 39:23 – Challenges in Psychedelic Treatment 43:01 – Corporate Interests and Scientific Objectivity 47:20 – Ketamine and Collaborative Research 51:56 – Ibogaine Patient Survey 57:55 – Psychedelics and Pain Research 01:07:22 – Conclusion and Future Directions
No Priors: Artificial Intelligence | Machine Learning | Technology | Startups
In the generative AI revolution, quality data is a valuable commodity. But not all data is created equally. Sarah Guo and Elad Gil sit down with SurgeAI founder and CEO Edwin Chen to discuss the meaning and importance of quality human data. Edwin talks about why he bootstrapped Surge instead of raising venture funds, the importance of scalable oversight in producing quality data, and the work Surge is doing to standardize human evals. Plus, we get Edwin's take on what Meta's investment into Scale AI means for Surge, as well as whether or not he thinks an underdog can catch up with OpenAI, Anthropic, and other dominant industry players. Sign up for new podcasts every week. Email feedback to show@no-priors.com Follow us on Twitter: @NoPriorsPod | @Saranormous | @EladGil | @echen | @HelloSurgeAI Chapters: 00:00 – Edwin Chen Introduction 00:41 – Overview of SurgeAI 02:28 – Why SurgeAI Bootstrapped Instead of Raising Funds 07:59 – Explaining SurgeAI's Product 09:39 – Differentiating SurgeAI from Competitors 11:27 – Measuring the Quality of SurgeAI's Output 12:25 – Role of Scalable Oversight at SurgeAI 14:02 – Challenges of Building Rich RL Environments 16:39 – Predicting Future Needs for Training AI Models 17:29 – Role of Humans in Data Generation 21:27 – Importance of Human Evaluation for Quality Data 22:51 – SurgeAI's Work Toward Standardization of Human Evals 23:37 – What the Meta/ScaleAI Deal Means for SurgeAI 24:35 – Edwin's Underdog Pick to Catch Up to Big AI Companies 24:50 – The Future Frontier Model Landscape 26:25 – Future Directions for SurgeAI 29:29 – What Does High Quality Data Mean? 32:26 – Conclusion
This week on The Beat, CTSNet Editor-in-Chief Joel Dunning speaks with CTSNet Senior Editor Dr. Sameh Said, Chief of the Division of Pediatric and Adult Congenital Cardiac Surgery at Maria Fareri Children's Hospital, Professor of Surgery and Pediatrics at the New York Medical College, and Consultant Cardiac Surgeon at King Faisal Specialist Hospital and Research Center about performing the first successful ex utero intrapartum treatment (EXIT)-to-open atrial septectomy-to-rapid stage I Norwood palliation in a neonate with hypoplastic left heart syndrome and intact interatrial septum. Chapters 00:00 Intro 03:13 JANS 1, Cardiac Transplant 09:04 JANS 2, Lung Transplant 10:19 JANS 3, Cardiac Transplant 11:08 JANS 4, Lung Cancer 13:01 JANS 5, Thoracic 15:44 Video 1, Congenital Cardiac 17:53 Video 2, Cardiac 19:49 Video 3, Cardiac 21:50 Dr. Said Interview, EXIT Procedure 37:28 Upcoming Events 39:32 Closing They discuss the surgical steps involved in this groundbreaking procedure, including specific details about the surgery, the preparation undertaken prior to the operation, and the key factors that contributed to its success. Additionally, they covered the challenges encountered during this first successful EXIT procedure case, as well as the standard management practices for these cases at medical centers, such as fetal balloon atrial septostomy, along with postnatal transcatheter, surgical, or hybrid interventions and their associated surgical risks. Furthermore, they address the broader challenges faced when operating on patients with hypoplastic left heart syndrome, including the differences between restrictive atrial septum and intact atrial septum. Joel also highlights recent JANS articles on the current state and future directions of cardiac xenotransplantation, if age is a contraindication for lung transplantation in the elderly, a summary of the International Society for Heart and Lung Transplantation consensus conference on emerging understanding of antibodies and antibody-mediated rejection in heart transplantation, inflammatory diseases and risk of lung cancer among individuals who have never smoked, and active chest tube clearance added to an Enhanced Recovery After Cardiac Surgery (ERAS) program improves outcomes and reduces resource utilization. In addition, Joel explores a single incision mitral valve repair and LIMA-to-LAD bypass via a left anterior minithoracotomy, repair of post-infarction ventricular septal defect using a double patch sandwich technique, and reconstruction of the left trigone during the Commando procedure for invasive prosthetic aortic valve endocarditis. Before closing, Joel highlights upcoming events in CT surgery. JANS Items Mentioned 1.) Cardiac Xenotransplantation: Current State and Future Directions 2.) Lung Transplantation in the Elderly: Is Age a Contraindication? 3.) Summary of the International Society for Heart and Lung Transplantation Consensus Conference on Emerging Understanding of Antibodies and Antibody-Mediated Rejection in Heart Transplantation 4.) Inflammatory Diseases and Risk of Lung Cancer Among Individuals Who Have Never Smoked 5.) Active Chest Tube Clearance Added to an Enhanced Recovery After Cardiac Surgery (ERAS) Program Improves Outcomes and Reduces Resource Utilization CTSNET Content Mentioned 1.) Single Incision Mitral Valve Repair and LIMA-to-LAD Bypass via a Left Anterior Minithoracotomy 2.) Repair of Post-Infarction Ventricular Septal Defect Using a Double Patch Sandwich Technique 3.) Reconstruction of the Left Trigone During the Commando Procedure for Invasive Prosthetic Aortic Valve Endocarditis Other Items Mentioned 1.) Guest Editor Series: Coronary Arterial Anomalies—Pediatric and Adult Congenital 2.) Cardiac Surgical Arrest—An International Conversation Series 3.) Career Center 4.) CTSNet Events Calendar Disclaimer The information and views presented on CTSNet.org represent the views of the authors and contributors of the material and not of CTSNet. Please review our full disclaimer page here.
As an American living in the UK, Matthew Sherwood unpacks what Independence Day really means from across the pond—and what it reveals about the growing divide between the US and UK. From political chaos to economic stagnation, he explores why the two nations feel increasingly out of sync.The episode also dives into the rise of political disruptors like Nigel Farage and Elon Musk, before teasing what's next for the podcast: bold new formats and fresh perspectives.Timestamps00:00 - Independence Day Reflections03:37 - The Diverging Paths of the US and UK07:49 - Political Landscape and Economic Realities09:21 - New Formats and Future Directions
Episode 73 - Intergalactic BFR with Luke Hughes, PhD Summary In this episode, Johnny Owens and Dr. Luke Hughes discuss the applications of Blood Flow Restriction (BFR) in space and its potential to mitigate deconditioning in astronauts. They explore the physiological changes that occur in microgravity, the importance of exercise countermeasures, and the innovative research being conducted to understand the mechanisms behind BFR's effectiveness. The conversation also touches on the implications of BFR for bone health, clinical applications, and future research directions. Takeaways BFR is a promising tool for mitigating muscle and bone deconditioning in space. Fluid shifts in microgravity can lead to significant health issues for astronauts. BFR can enhance the effectiveness of low-intensity aerobic exercise. Research is ongoing to understand the mechanisms behind BFR's benefits for bone health. BFR protocols need to be personalized for different patient populations. The use of BFR in clinical settings shows potential for improving recovery outcomes. BFR can help prevent amputations in patients with severe vascular issues. Understanding the impact of pressure on blood flow is crucial for optimizing BFR protocols. BFR can be integrated into rehabilitation programs for various conditions. Future research will focus on the long-term effects of BFR in both space and clinical settings. Chapters 00:00 Introduction and Overview of Blood Flow Restriction (BFR) 05:38 Bed Rest Studies and Their Importance in Space Research 12:45 Physiological Effects of Microgravity on Astronauts 18:41 Current Exercise Countermeasures in Space Missions 24:04 Future Directions and Innovations in Space Exercise 24:33 Innovations in Exercise Devices for Space Missions 26:41 The Role of Blood Flow Restriction (BFR) in Space Exercise 29:20 First Experiments with BFR in Microgravity 30:37 Collaboration with SpaceX for In-Orbit Research 31:59 Developing Space-Compatible Exercise Devices 33:53 BFR Exercise in Space: A Historic Milestone 35:06 Exercise Protocols and Adjustments for Space Conditions 37:45 Initial Findings from BFR Experiments in Space 40:47 Exploring Fluid Shifts and BFR's Impact 43:33 Combining Aerobic Exercise with BFR for Enhanced Benefits 48:51 Future Directions in BFR Research and Applications 53:07 Exploring Bone Adaptation Mechanisms 55:37 Methodological Framework for Bone Research 59:30 Innovations in Bone Blood Flow Measurement 01:02:31 BFR Applications in Rehabilitation and Pain Management 01:05:17 Future Directions in BFR Research and Space Applications Podcast Intro Attribution Song: Legendary Music by: CreatorMix.com Video: https://youtu.be/_oaZzkn0bW4 Podcast Outro Attribution Song: Smoke Rising Music by: CreatorMix.com Video: https://youtu.be/_oaZzkn0bW4
On this episode of Trending in Education, Mike Palmer is joined by Elliot Felix, a returning guest, to discuss his new book, The Connected College: Leadership Strategies for Student Success. The book, releasing July 22nd, focuses on how higher education can become more agile, connected, and break down silos. Elliot Felix shares his mission of student success, drawing on his experience consulting with over 120 colleges and universities to improve student experiences through transformations in physical spaces, support services, and technology systems. He explains that his new book aims to provide an evidence-based playbook for higher education professionals to collaborate better for student success. Key Takeaways: Addressing Disconnections in Higher Ed: Felix identifies five key disconnections the book addresses, including a lack of belonging among students (only 65% feel they belong), the disconnect between courses and careers, and the prevalence of siloed structures within institutions. He illustrates this with an example of a university having both a "writing lab" and a "writing center" performing similar functions due to historical and structural reasons. The Connected College Vision: Felix envisions a future where colleges and universities are better connected, leading to students feeling a stronger connection to their institution, their coursework linking to careers, and increased collaboration both internally and with external partners like corporations and community groups. Defining Student Success: The conversation delves into the multifaceted definition of student success, acknowledging that it can be viewed through metrics like retention and graduation rates, student engagement and belonging, or the individual student's perspective of success. Felix suggests common ground for student success includes students finding their community, their academic and career path, their place, and a sense of purpose. Silo Busting Strategies: Felix highlights that silos are common in organizations, particularly in higher education, which is designed for durability. He attributes this to a lack of clear strategy beyond broad, anodyne statements, and legacy structures that simply have new functions "bolted on" rather than integrated. Tactics for breaking down silos include sharing data to create a common understanding of students. Forward-Thinking Universities: Examples of innovative approaches include university-industry partnerships driving economic and workforce development, such as Carnegie Mellon's robotics innovation center and Rowan University's expansion into health and wellness and advanced manufacturing. Other examples include Imperial College London's enterprise lab, the University of South Florida's focus on entrepreneurship, and Arizona State's "Work Plus Learn" program. Don't miss Elliot's new book, The Connected College: Leadership Strategies for Student Success, available July 22nd wherever you get your books. Subscribe to Trending in Ed so you never miss a conversation about leading the future of education in these transformative times. 00:00 Introduction and Guest Welcome 01:07 Elliot Felix's Background and Mission 02:26 The Connected College: Themes and Issues 06:28 Book Structure and Innovator Profiles 07:54 Defining Student Success 13:23 Silo Busting in Higher Education 17:14 AI and Future Trends in Higher Ed 20:36 The Importance of Combining Skills in Higher Education 21:06 Collaborative Spirit in Developing AI Policies 22:26 Navigating Political and Technological Disruptions 31:15 The Role of Higher Education in Economic Development 31:43 Innovative University-Industry Partnerships 33:08 Spotlighting Success Stories in Higher Education 35:49 Concluding Thoughts and Future Directions
Fill out this short listener survey to help us improve the show: https://forms.gle/bbcRiPTRwKoG2tJx8In this episode, Simon Eskildsen, co-founder and CEO of TurboPuffer, lays out a compelling vision for how AI-native infrastructure needs to evolve in an era where every application wants to connect massive amounts of context to large language models. He breaks down why traditional databases and even large context windows fall short—especially at scale—and why object-storage-native search is the inevitable next step. Drawing on his experience from Shopify and Readwise, Simon introduces the SCRAP framework to explain the limits of context stuffing and makes a clear case for why cost, recall, performance, and access control drive the need for smarter retrieval systems. From practical lessons in building highly reliable infra to hard technical problems in vector indexing, this conversation distills the future of AI infra into first principles—with clarity and depth. [0:00] Intro[0:49] The Evolution of AI Context Windows[2:32] Challenges in AI Data Integration[3:56] SCRAP: Scale, Cost, Recall, ACLs, and Performance[9:21] The Rise of Object-Oriented Storage[16:47] Turbo Puffer Use Cases[22:32] Challenges in Vector Search[27:02] Challenges in Query Planning and Data Filtering[27:53] Focusing on Core Problems and Simplicity[28:28] Customer Feedback and Future Directions[29:11] Reliability and Simplicity in Design[30:39] Evaluating Embedding Models and Search Performance[32:17] The Role of Vectors in Search Engines[34:16] Balancing Focus and Expansion[35:57] AI Infrastructure and Market Trends[38:36] The Future of Memory in AI[43:01] Table Stakes for AI in SaaS Applications[45:55] Multimodal Data and Market Observations[46:57] Quickfire With your co-hosts: @jacobeffron - Partner at Redpoint, Former PM Flatiron Health @patrickachase - Partner at Redpoint, Former ML Engineer LinkedIn @ericabrescia - Former COO Github, Founder Bitnami (acq'd by VMWare) @jordan_segall - Partner at Redpoint
After nearly a decade of podcasting, Nick and Tyler hit record on a candid, unscripted conversation about burnout, direction, and the deeper purpose behind The Modern Craftsman. This episode pulls back the curtain on their evolving goals, the emotional toll of running a business, and the pressures of staying relevant in a saturated market. From questioning what growth really means to re-centering the show on meaningful conversations—not metrics—this is a raw, honest reset that long-time listeners won't want to miss. Show Notes: Pause and Reflection on the Podcast (0:00) Sponsor Acknowledgements and Podcast Content (1:59) Evaluating Podcast Content and Guest Selection (4:38) Exploring Broader Topics and Guest Insights (18:30) Balancing Personal and Professional Growth (20:47) Navigating Emotional and Business Challenges (24:34) Engaging with Listeners and Future Directions (1:04:36) Video Version: https://youtu.be/tISDDZMj6fU Partners: Andersen Windows Buildertrend Harnish Workwear Use code H1025 and get 10% off their H-label gear The Modern Craftsman: linktr.ee/moderncraftsmanpodcast Find Our Hosts: Nick Schiffer Tyler Grace Podcast Produced By: Motif Media
In this episode of the Boost Your Biology podcast, Lucas Aoun interviews Dr. Jonathann Kuo, an expert in longevity science and the founder of Extension Health. They discuss Dr. Kuo's journey into regenerative medicine, the shift in pain management practices, the significance of the vagus nerve, and innovative therapies such as plasmapheresis and hyperbaric therapy. The conversation also covers the role of peptides in health optimization, advancements in weight loss therapies, and the future of stem cell research. Dr. Kuo shares insights on the importance of personalized medicine and the exciting developments in the field of longevity.Relevant links:Dr Jonathan Kuo's IG: https://www.instagram.com/dr.kuo/ Check Out My Website For Coaching, Recommended Products and Much More:https://www.boostyourbiology.com/ Disclaimer:The information provided in this podcast episode is for entertainment purposes and is NOT MEDICAL ADVICE. The products presented and discussed in this podcast are explicitly only relevant to those who reside in the US. The statements and discussions held within this episode, are NOT approved by the TGA. If you have any questions about your health, contact a medical professional. This content is strictly the opinions of Lucas Aoun and is for informational and entertainment purposes only. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All viewers of this content are advised to consult with their doctors or qualified health professionals regarding specific health questions. Neither Lucas Aoun nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this content. All consumers of this content especially taking prescription or over-the-counter medications should consult their physician before beginning any nutritional, supplement or lifestyle program.Chapters00:00 Introduction to Longevity Science02:54 Journey into Regenerative Medicine05:50 The Shift in Pain Management08:51 Understanding the Vagus Nerve11:45 Neuro Reset Procedure Explained14:24 Peptides and Their Role in Health17:16 Advancements in Weight Loss Therapies20:05 The Future of Stem Cell Research22:53 Plasmapheresis and Its Benefits25:53 Hyperbaric Therapy Insights28:43 Innovations in Peptide Delivery31:32 The Role of AI in Medicine34:25 Future Directions for Extension Health Hosted on Acast. See acast.com/privacy for more information.
In this episode of A Shot in the Arm podcast, host Ben Plumley is joined by Professor Heidi Larson, co-founder of the Global Listening Project, and Dr. Nduku Kilonzo, managing director of Yemaya Health Advisory. Recorded in during IAS 2025 in Kigali, Rwanda, the discussion centers on the essential contributions of faith leaders to global health, particularly in engaging communities and influencing public health decisions. The episode explores findings from the Global Listening Project's studies in Kenya and Nigeria, highlighting the deep trust communities place in faith leaders and the necessity of including them in health initiatives. The conversation emphasizes the need for health professionals to rethink their engagement strategies with faith communities, the role of digital technologies, and the importance of co-creating health solutions with faith leaders. 00:00 Introduction and Welcome 00:17 Meet the Guests: Professor Heidi Larson and Dr. Nduku Kilonzo 00:35 The Role of Faith Leaders in Global Health 02:20 Insights from the Global Listening Project 03:54 Challenges and Opportunities in Engaging Faith Leaders 05:17 Deep Listening Techniques and Findings 07:49 Faith Leaders' Perspectives on Health Issues 09:53 The Importance of Trust and Engagement 19:11 Digital Technologies and Faith Communities 24:27 Future Directions and Final Thoughts 28:30 Closing Remarks and Thanks
SummaryIn this episode of the Upgrade America podcast, the hosts delve into various contemporary issues ranging from corporate scandals and workplace culture to the complexities of marriage and infidelity. They discuss the implications of automation and AI on employment, the rising costs of traditional lifestyles, and the challenges of education accessibility. The conversation also touches on Gen Z's movement towards off-grid living as a response to technology overload, highlighting the need for a more balanced approach to life in the modern world. This conversation explores the evolving dynamics of communication across generations, particularly focusing on the preferences of Generation Alpha for more personal interactions over digital communication. It delves into the impact of technology on social interactions, the mental health implications of isolation, and the importance of engaging in meaningful projects. The discussion also touches on the rise of AI and deep fakes, the racial dynamics in digital spaces, and the quest for black unity and land ownership. Additionally, it addresses the role of ICE in immigration and the potential for building alliances between black Americans and immigrant communities, particularly in southern states. Finally, the conversation wraps up with reflections on pop culture, including the upcoming Mortal Kombat movie and superhero films.Chapters00:00 Introduction to the Podcast and Themes01:00 Corporate Scandals and Workplace Culture04:55 Marriage Dynamics and Infidelity09:48 Work-Life Balance and Remote Work16:35 Financial Expectations in Relationships23:11 The Impact of Automation and AI on Jobs31:40 The Future of Governance and AI38:37 Education and Accessibility44:27 Gen Z and the Movement Towards Simplicity45:44 Generational Shifts in Communication48:25 The Impact of Technology on Social Interaction51:14 Isolation and Mental Health53:07 Finding Flow: Projects as a Cure for Depression54:08 The Rise of AI and Deep Fakes56:41 Navigating Social Media in a Post-Reality Era59:30 Digital Moderation and Racial Dynamics01:01:27 The Fear of Black Unity and Retaliation01:05:44 Building Community and Land Ownership01:08:42 The Role of ICE and Immigration Dynamics01:10:37 The Need for Solidarity Among Marginalized Groups01:12:05 Potential for Political Control in Southern States01:15:25 Cultural Representation in Media01:23:08 Anticipating Future Media Releases01:28:01 Final Thoughts and Future Directions
Are your current stroke interventions in line with the latest clinical data? Dr. Blaise Baxter, interventional radiologist at Sutter Health, and Dr. Jim Milburn, interventional neuroradiologist at the Ochsner Health, join host Dr. Michael Barraza to discuss the latest advancements in stroke interventions. --- This podcast is supported by: Imperative Carehttps://imperativecare.com/stroke/zoom-stroke-solution/ --- SYNPOSIS The episode begins with a discussion on the different pathways to becoming a neurointerventionalist, emphasizing why interventional radiologists are uniquely equipped for this transition. They dive into cutting-edge stroke interventions, sharing key takeaways from major trials on large core and medium vessel occlusions. Dr. Baxter and Dr. Milburn highlight the HERMES trial, which showed that endovascular thrombectomy led to beneficial effects on patients with anterior circulation occlusion. They then cover the BAOCHE trial, which showed better functional outcomes with thrombectomy over medical therapy. Milburn and Baxter also share their perspectives on the shifting role of perfusion imaging and why the field may be moving beyond it. To close the discussion, the doctors underscore the powerful impact of rehabilitation in driving patient recovery, and stress the ongoing need for innovation and improved training in the field of neurointerventional radiology. --- TIMESTAMPS 00:00 - Introduction06:18 - Training and Certification in Neurointervention13:11- Large Core Trials and Their Impact19:42 - CT Perfusion and Treatment Decisions29:45 - Understanding Stroke Scale Scores and ICAD30:31 - Thrombectomy Trials and Treatment Strategies34:48 - Challenges in Randomizing Patients for Trials44:25 - Advancements in Robotics and Stroke Treatment51:37 - Future Directions in Stroke Rehabilitation53:11 - Global Thrombectomy Adoption and Training --- RESOURCES Hermes trial: Goyal M, Menon BK, van Zwam WH, et al. Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials. Lancet. 2016;387(10029):1723-1731. doi:10.1016/S0140-6736(16)00163-X BAOCH trial: Jovin TG, Li C, Wu L, et al. Trial of Thrombectomy 6 to 24 Hours after Stroke Due to Basilar-Artery Occlusion. N Engl J Med. 2022;387(15):1373-1384. doi:10.1056/NEJMoa2207576
In this episode of the Diabetes Innovators Series, the conversation explores the evolution of diabetes treatment, the challenges faced in managing diabetes today, and the future of diabetes research. Zan, an endocrinologist and former FDA executive and Founder and executive chairman of Kinexum, shares insights from his career, including the historical context of diabetes management, the importance of A1C as a marker, and the potential of new treatments like GLP-1 agonists. The discussion also touches on the concept of meta-abesity, the shared root causes of chronic diseases, and the need for a focus on health span rather than just lifespan. Chapters 00:00 Introduction to Diabetes Innovation Series 03:06 Zan's Journey in Diabetes Research 06:05 Transforming Diabetes Treatment: A Historical Perspective 09:00 The Evolution of Diabetes Management Tools 11:42 Challenges in Diabetes Management Today 14:41 The Future of Diabetes Treatment: Aiming for a Cure 17:57 Understanding the Drug Approval Process 20:32 Meta-Abesity: A New Perspective on Chronic Diseases 23:48 Innovations in Longevity and Health Span 26:27 The Role of GLP-1 Agonists in Diabetes Management 29:29 Future Directions in Diabetes Research 32:29 Memorable Moments in Drug Proposals 35:37 Conclusion and Future Collaborations Resources: Kinexum Zan Fleming
In this episode, the hosts discuss 'Jump' the long-awaited comeback of BLACKPINK after three years! They dive into the visuals, production choices, the impact of AI in music videos and speculate on the future direction of BLACKPINK as they approach their 10-year anniversary. They also share Hit Replays From TWICE, BABYMONSTER & Yung Raja x Jay ParkJoin the Kpopcast Slack: https://join.slack.com/t/kpopcast/shared_invite/zt-93kzxcv6-YNej2QkyY6vaPnhEQJxk0AChip in for editing: https://ko-fi.com/thekpopcast HIT REPLAYS:BABYMONSTER - ‘HOT SAUCE' M/V https://youtu.be/xn8mQqz2xmM?si=kPledLm0LbCJBi98 Yung Raja x Jay Park ‘missed call' https://youtu.be/spDokk5zl-0?si=7XpjEOuYL5-S6E2v BATTITUDE (NAYEON, JEONGYEON, MOMO, MINA) https://youtu.be/TOic7n-CDd4?si=aTfzQTwPr0sMl19p Chapters00:00 Introduction to K-Pop Hits00:29 BABYMONSTER03:33 Jay Park x Young Raja05:56 TWICE's New Era and Attitude10:08 BLACKPINK Deep Dive11:49 Live Reaction to BLACKPINK's 'Jump'17:36 Comparative Discussion: 'Jump' vs. Previous Releases22:40 Audio Quality and Production Choices28:40 The Impact of AI on Authenticity34:20 Rushed Releases and Quality Concerns38:13 Future Directions for Blackpink Hosted on Acast. See acast.com/privacy for more information.
In this episode, we explore the intersection of ovarian health, menopause, and AI technology with Kiran, the founder of TimelessBioTech. The conversation delves into the importance of ovarian longevity for women's health, the predictive tools being developed to forecast menopause timing, and the various interventions that can support ovarian health. Kiran shares insights on hormonal balance, the role of lifestyle factors, and the future of personalized health strategies for women. The discussion emphasizes the need for targeted solutions and the potential for AI to revolutionize women's health care.Timeless Biotech WebsiteKiran's email for investors, clinics, and companies looking to invest in or work with Timeless: Kiiran@timelessbiotech.comThis episode is brought to you by OneSkin, the longevity scientists behind the first topical peptide scientifically proven to reverse skin aging—now bringing their expertise to your scalp. If you care about aging well, you can't ignore your hair. The health of your scalp directly impacts the strength, thickness, and lifespan of every strand. That's why OneSkin created their new OS-01 HAIR, the first scalp serum powered by a longevity peptide designed to optimize follicle health, balance the scalp, and extend the healthspan of your hair follicles. In their clinical study, OS-01 HAIR showed significant improvements in hair density, thickness, and overall scalp health—all by targeting follicle aging at the root. I've been using it myself and I'm genuinely impressed. It's lightweight, fragrance-free, and backed by science—not fluff. If you're serious about keeping your hair vibrant and resilient as you age, I highly recommend giving OneSkin's OS-01 HAIR a try. Head to oneskin.co/KAYLA for 15% off your order. About KiranKiran Kumar is the Founder & CEO of Timeless Biotech, an early-stage ovarian longevity company that has prototyped the first-ever time-to-menopause predictor and ovarian age clock. Kiran is a Biotechnology Bioengineer from UC San Diego, and has contributed to research in ML-powered diagnostics.Kiran has worked in numerous longevity and wellness startups such as FOXO Technologies, OneSkin, and Timeline where she authored. research-backed contentKiran's work sits at the intersection of Physiology, AI, and Longevity.Chapters00:00 Introduction to Ovarian Longevity and AI Solutions02:44 The Importance of Ovarian Health in Longevity05:38 Understanding Menopause and Ovarian Aging08:48 Predictive Tools for Menopause Timing11:32 Interventions for Ovarian Longevity14:31 The Role of Hormones in Ovarian Health17:25 Innovative Approaches to Hormonal Balance20:14 The Future of Ovarian Health Technologies22:58 Personalized Health Strategies for Women25:31 Conclusion and Future Directions
Send us a textIn this episode of Causes or Cures, Dr. Eeks chats with immunology expert Dr. Maziar “Maz” Divangahi about how a fiber found in mushrooms may help us beat the flu, and he introduces us to the concept of disease tolerance. What We'll CoverBeta-Glucan 101What it is: a natural fiber in the outer wall of fungi (think mushrooms).Why it matters: mounting evidence says it can help you fight off the flu by improving something called disease tolerance. Two Immune PlaybooksHost Resistance: the classic “seek and destroy” tactic.Disease Tolerance: a quieter, damage-control strategy our bodies use to stay functional even when a pathogen sticks around.Dr. Maz will unpack how beta-glucan may tilt the balance toward disease tolerance.From TB Labs to Flu ResearchInsights from Dr. Maz's tuberculosis studies that set the stage for his beta-glucan–flu work.Early data on how this fungal fiber might boost flu-specific disease tolerance.Should We Eat More Mushrooms or Supplement?Practical tips and caveats on dietary vs. supplemental beta-glucan.What the current evidence actually supports.Beyond Infections: Beta-Glucan in Cancer TrialsSnapshot of ongoing studies in breast and bladder cancer.Why disease tolerance is a hot oncology frontier.Future Directions & Take-Home PointsWhere Dr. Maz's research is headed next.Simple, science-backed actions listeners can try today.Listen If You've Ever Wondered…Why some people sail through the flu while others end up in the ER.Whether “disease tolerance” might rewrite how we tackle pandemics.If tossing extra shiitakes into your stir-fry can really make a difference.Dr. Maziar (Maz) Divangahi is a Professor of Medicine at McGill University. He is the Associate Director of the Meakins-Christie Laboratories and the Associate Director of the McGill Interna onal TB Centre. He is an internationally recognized pulmonary immunologist and the overarching focus of his research program is to inves gate the regulatory mechanisms involved in host resistance and disease tolerance against major pulmonary bacterial (Mycobacterium tuberculosis) and viral (influenza virus and SARS-CoV2) pathogens. He is currently inves ga ng how to harness the power of innate memory response (Trained Immunity) in vaccine development. Throughout his career, he has been a prolifera ve inves gator publishing in outstanding journals and received numerous awards, including a CIHR New Inves gator Award, FRQS Award, and the CIHR Founda on grant. His scholarly work has been recognized by elec on to the Royal Society of Canada. He is currently holding the Strauss Chair in Respiratory Diseases. You can contact Dr. Eeks at bloomingwellness.com.Follow Eeks on Instagram here.Or Facebook here.Or X.On Youtube.Or TikTok.SUBSCRIBE to her monthly newsletter here! (Now featuring interviews with top experts on health you care about!)Support the show
Shownotes Who is the ideal candidate for genicular artery embolization (GAE)? In this BackTable Brief, Dr. Osman Ahmed and Dr. Sid Padia share how they work up and select GAE patients. Dr. Padia and Dr. Ahmed discuss the challenges of patient selection in genicular artery embolization, specifically debating the necessity and utility of MRI with contrast. The discussion also explores the pros and cons of femoral vs. pedal access techniques, considering patient characteristics such as BMI and the practicality of these approaches in various clinical settings. Episode Outline 00:00 - Introduction 00:20 - Use of MRI with Contrast in Patient Selection 04:22 - Challenges and Future Directions of MRI in GAE 07:46 - Pros and Cons of Femoral vs. Pedal Access 10:00 - Practical Considerations Resources Dr. Venkatesh, “Kavi”, Krishnasamy, MD https://www.uab.edu/medicine/radiology/faculty/intervent-radiology/profile/krishnasamy Dr. Osman Ahmed, MD https://bucksbauminstitute.uchicago.edu/bio/osman-ahmed-md/ Dr. Siddarth, “Sid”, Padia, MD https://www.uclahealth.org/providers/siddharth-padia
On Episode #173 of the PricePlow Podcast, Mike and Ben dive deep into the world's most researched supplement with Mirko Holzmüller and Stefan Schweyer from Creapure, the premium creatine monohydrate brand manufactured by AlzChem in Germany. This comprehensive conversation explores everything from the unique German manufacturing process that delivers 99.99% purity to the expanding research showing creatine's benefits far beyond athletic performance. As creatine experiences a renaissance with growing interest from women, elderly populations, and health-conscious consumers, Mirko and Stefan provide insider insights into what sets Creapure apart from generic alternatives. From the coal-and-lime production process in Bavaria to the rigorous testing protocols that ensure every batch meets pharmaceutical-grade standards, this episode reveals why leading brands like Nutristat choose Creapure as their exclusive creatine source. The discussion covers optimal dosing strategies, debunks common myths about loading phases, and explores emerging research on post-viral fatigue, cognitive function, and healthy aging. Whether you're a supplement industry professional or someone curious about creatine's expanding applications, this conversation offers unprecedented access to the science and manufacturing expertise behind the world's most trusted creatine brand. https://blog.priceplow.com/podcast/creapure-173 Video: Inside Creapure - The Science of Premium Creatine Manufacturing https://www.youtube.com/watch?v=rJe2nesRtkw Detailed Show Notes: Creapure's Manufacturing Excellence and Scientific Leadership (0:00) – Introduction: Meeting the Creapure Team (5:00) – AlzChem's Foundation: More Than Just Creatine (10:00) – Creatine Fundamentals: Energy Currency for Body and Brain (15:00) – Personal Dosing Strategies: Beyond the Standard Five Grams (20:00) – Understanding Creatine's Unique Energy Profile (25:00) – Manufacturing Excellence: The German Advantage (30:00) – Purity Standards: 99.99% Excellence (35:00) – Quality Control and Contamination Prevention (40:00) – Market Trends and Consumer Education (45:00) – Research Partnerships and Scientific Leadership (50:00) – Creatine Forms and Research Evidence (55:00) – Practical Use and Dosing Strategies (60:00) – Product Forms and Delivery Methods (65:00) – Quality Assurance and Brand Protection (70:00) – Regulatory Compliance and Health Claims (75:00) – Future Directions and Consumer Access Where to Follow Creapure and Learn More Creapure Website: Creapure.com Instagram: @Creapure Email: info@creapure.com Mirko Holzmüller: LinkedIn Stefan Schweyer: LinkedIn Educational Resources: Creapure Manufacturing Process AlzChem Company Overview ... Read more on the PricePlow Blog
Send us a textChristian fiction is evolving—and so are its authors. In this episode, we explore current trends, predict where the genre is headed, and share how indie writers can innovate while staying true to their faith and message.Whether you're a seasoned indie author or just starting your writing journey, we'll equip you with insights, inspiration, and practical tips to stay ahead of the curve—without compromising your message or mission.Tune in as we explore how to write stories that reflect a living faith in a rapidly evolving literary world.
In this episode of the podcast, host Fabian Alefeld interviews Chris Holshouser, Deputy Program Director of Maritime Systems at BlueForge Alliance. They discuss the Navy's ambitious projects, focusing on advanced technologies like additive manufacturing, supply chain optimization, and workforce development. Chris elaborates on the challenges and goals associated with the Columbia and Virginia class submarines, the importance of enhancing the maritime industrial base, and the need for skilled labor in manufacturing. The conversation also touches on the establishment of the Additive Manufacturing Center of Excellence, partnerships with various organizations, and the long-term vision for modernization and technological integration in shipbuilding. More information on the Maritime Industrial Base Additive Manufacturing Excellence training available here. 01:23 Meet Chris and BlueForge Alliance 02:37 Mission and Impact of BlueForge Alliance 04:32 Understanding the US Navy's Triad and Submarine Classes 07:03 Challenges in Modernizing the Industrial Base 12:30 Role of Additive Manufacturing in the Navy 19:26 Understanding Metallurgy in Welding 19:40 Applications and Supply Chain Impact 21:22 Certification and Qualification Process 22:42 Additive Manufacturing in Practice 24:19 Challenges and Opportunities in Additive Manufacturing 28:17 Interdisciplinary Nature of Additive Manufacturing 30:18 Evaluating Parts for Additive Manufacturing 32:54 Advancements in Additive Manufacturing 37:01 Future Directions and Call to Action
Sensorimotor Dysfunction & the Cervical Spine: What Clinicians Miss After Concussion | Dr. Julia Treleaven Part I
Proudly sponsored by PyMC Labs, the Bayesian Consultancy. Book a call, or get in touch!Intro to Bayes Course (first 2 lessons free)Advanced Regression Course (first 2 lessons free)Our theme music is « Good Bayesian », by Baba Brinkman (feat MC Lars and Mega Ran). Check out his awesome work!Visit our Patreon page to unlock exclusive Bayesian swag ;)Takeaways:INLA is a fast, deterministic method for Bayesian inference.INLA is particularly useful for large datasets and complex models.The R INLA package is widely used for implementing INLA methodology.INLA has been applied in various fields, including epidemiology and air quality control.Computational challenges in INLA are minimal compared to MCMC methods.The Smart Gradient method enhances the efficiency of INLA.INLA can handle various likelihoods, not just Gaussian.SPDs allow for more efficient computations in spatial modeling.The new INLA methodology scales better for large datasets, especially in medical imaging.Priors in Bayesian models can significantly impact the results and should be chosen carefully.Penalized complexity priors (PC priors) help prevent overfitting in models.Understanding the underlying mathematics of priors is crucial for effective modeling.The integration of GPUs in computational methods is a key future direction for INLA.The development of new sparse solvers is essential for handling larger models efficiently.Chapters:06:06 Understanding INLA: A Comparison with MCMC08:46 Applications of INLA in Real-World Scenarios11:58 Latent Gaussian Models and Their Importance15:12 Impactful Applications of INLA in Health and Environment18:09 Computational Challenges and Solutions in INLA21:06 Stochastic Partial Differential Equations in Spatial Modeling23:55 Future Directions and Innovations in INLA39:51 Exploring Stochastic Differential Equations43:02 Advancements in INLA Methodology50:40 Getting Started with INLA56:25 Understanding Priors in Bayesian ModelsThank you to my Patrons for making this episode possible!Yusuke Saito, Avi Bryant, Ero Carrera, Giuliano Cruz, James Wade, Tradd Salvo, William Benton, James Ahloy, Robin Taylor,, Chad
In this episode of the Diabetes Innovators Series, Rob interviews Dr. Anath Shalev discussing the recent advancements in TIXiMed's TIX100, an oral therapy for type 1 diabetes. The conversation covers the successful completion of a phase one study, the implications of the results, and the potential impact of TIX100 on diabetes management. Dr. Shalev emphasizes the importance of addressing beta cell dysfunction and the exciting metabolic signals observed during the study. The discussion also touches on the future directions for TIX100 and its role in improving the lives of diabetes patients. Chapters Chapters 00:00 Introduction to TixiMed and TIX100 01:16 Phase One Study Results and Implications 05:22 Metabolic Signals and Future Studies 08:11 The Role of TIX100 in Diabetes Management 09:47 Future Directions and Patient Impact Resources: TIXiMED Dr. Anath Shalev
Featuring perspectives from Dr Anne Chiang, Ms Elizabeth Krueger, Ms Beth Sandy and Dr Erin Schenk, including the following topics: Introduction: Overview of Bispecific Antibodies (0:00) Biology of Small-Cell Lung Cancer (SCLC) and Review of Its Initial Management (13:37) Case: 63-year-old man — Ms Krueger (23:36) Current Role of Tarlatamab in Therapy for SCLC (33:40) Case: 70-year-old woman — Ms Sandy (43:41) Future Directions in the Management of SCLC (50:45) Case: 81-year-old man — Ms Krueger (1:01:24) Unique Considerations in SCLC Management (1:09:29) Case: 67-year-old woman — Ms Sandy (1:22:53) NCPD information and select publications
This week please join guest author Adam Griesemer and Associate Editor and Digital Strategies Editor Maryjane Farr as they discuss the Review Article "Cardiac Xenotransplantation: Current State and Future Directions." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250707.102697
This podcast discusses the evolution and importance of telemedicine in operational environments, particularly in military settings. It highlights case studies that demonstrate the need for telemedical support during prolonged field care, the challenges faced by medical teams, and the current solutions available. The conversation emphasizes the significance of training, effective communication, and the integration of technology to enhance patient care in remote and challenging environments.Listen to this podcast AD FREE with premium Membership on Spotify, Apple Podcast, and PatreonTakeawaysTelemedicine is rapidly evolving to support operational environments.Case studies illustrate the critical need for telemedical support.Challenges exist in current medical support systems, particularly in remote areas.Prolonged field care requires innovative solutions like telemedicine.Telemedicine is defined as remote evaluation and consultation using technology.Current telemedical solutions have limitations that need addressing.Future innovations in telemedicine may include AI and robotics.Training is essential for effective telemedical consultations.Asking for help through telemedicine is a sign of strength, not weakness.Technology must be reliable, convenient, and adaptable to various situations.Chapters00:00 Introduction to Telemedicine in Operational Environments02:43 Case Studies Highlighting Telemedical Support05:56 Challenges in Current Medical Support Systems08:35 The Need for Telemedicine in Prolonged Field Care11:53 Defining Telemedicine and Its Importance14:45 Current Telemedical Solutions and Their Limitations17:44 Future Directions and Innovations in Telemedicine20:35 Operational Telemedicine: Best Practices and Recommendations23:24 Q&A Session: Addressing Concerns and Future Growth26:35 Conclusion and Final Thoughts on TelemedicineThank you to Delta Development Team for in part, sponsoring this podcast.deltadevteam.comFor more content, go to www.prolongedfieldcare.orgConsider supporting us: patreon.com/ProlongedFieldCareCollective or www.lobocoffeeco.com/product-page/prolonged-field-care
This episode of the VJHemOnc podcast focuses on the treatment of elderly or unfit patients with acute myeloid leukemia (AML).... The post Treating elderly or unfit patients with AML: current approach and future directions appeared first on VJHemOnc.
In this episode of the PFC Podcast, Ramey Wilson discusses the evolving landscape of Global Health Engagement (GHE) and its critical role in military medicine. He emphasizes the importance of interoperability in crisis standards of care, sharing real-world examples of medical collaboration in operational settings. The conversation highlights the need for a framework that addresses crisis capability gaps and the psychological protection of medical personnel in challenging situations. Ramey also explores future directions for medical engagement and the importance of preparing for various operational contexts.TakeawaysGlobal Health Engagement is evolving and critical for military operations.Interoperability is essential for effective crisis response.Crisis standards of care must be established for operational readiness.Understanding partner capabilities is vital for effective medical support.Real-world examples illustrate the importance of collaboration in medical care.Psychological protection for medical personnel is crucial in crisis situations.Future medical engagement should focus on sustainable practices.Risk assessment is a key component of medical decision-making.Training must align with the operational context and partner capabilities.Crisis standards of care can enhance the effectiveness of medical operations.Chapters00:00 Introduction to Global Health Engagement02:38 Interoperability in Crisis Standards of Care05:42 The Role of Global Health Engagement09:02 Crisis Capability Gap and Medical Support11:51 Real-World Examples of Medical Collaboration14:41 Crisis Standards of Care and Ethical Considerations17:57 Framework for Crisis Standards of Care20:46 Future Directions in Global Health EngagementThank you to Delta Development Team for in part, sponsoring this podcast.deltadevteam.comFor more content, go to www.prolongedfieldcare.orgConsider supporting us: patreon.com/ProlongedFieldCareCollective or www.lobocoffeeco.com/product-page/prolonged-field-care
Mel is back! We are hear to discuss some things going on with the prolife movement. We discuss the significant impact of the Dobbs decision on the pro-life movement, reflecting on personal experiences and the cultural shifts surrounding motherhood and abortion. We explore the implications of state laws on abortion access, the Adriana Smith case, and the importance of community and collaboration in pro-life activism. The conversation also highlights insights from the Live Action Women's Summit, emphasizing the need for empathy in discussions about abortion and the future direction of the pro-life movement.Chapters00:00 Introduction and Catching Up04:15 Reflections on the Dobbs Decision06:58 Impact of Dobbs on Abortion Laws07:51 Personal Experiences in the Pro-Life Movement09:55 Challenges and Opportunities Post-Dobbs12:31 State Responses to Abortion Legislation15:13 Future Directions for the Pro-Life Movement27:59 Engaging with Local Pro-Life Communities30:50 The Power of Conversations in Pro-Life Advocacy34:18 Crossing Political Aisles for Pro-Life Progress37:39 The Case of Adriana Smith and Baby Chance50:53 Reflections from the Live Action SummitFollow on Instagram:TOG: @thoseothergirlspodcastMal: @malyourgalpal This is a Other Girls Media production.You are able to listen on Apple Podcasts, Spotify, iHeartRadio, Google Podcast, Amazon Music, Pandora PLUS YouTube.Join ourPatreonSponsors:COL 192:https://col1972.com/ "thoseothergirls1972"America Women Beauty:https://americanwomanbeauty.net/ "mal15"Garnuu:https://garnuu.com/ "othergirls10"The Pink Rose:https://shopthepinkrose.com/ "othergirls10"Want more TOG?Get theappCheck out ourwebsiteOrderMerchThose Other Girls Rumble ChannelThose Other Girls Youtube Channel
With BCG in short supply and recurrence rates still high, the race is on for better intravesical options. In this episode of BackTable Tumor Board, Dr. Lindsey Herrel, urologic oncologist at the University of Michigan, joins Dr. Ruchika Talwar to explore the evolving landscape of intravesical therapy for intermediate risk bladder cancer. --- This podcast is supported by an educational grant from UroGen Pharma. --- SYNPOSIS The doctors break down the nuances of defining this risk category and the clinical gray zones that complicate treatment decisions. Dr. Herrell shares her patient-centered approach to surveillance and therapy, and introduces promising new agents, including Anktiva, UGN-102, and the gemcitabine-releasing TAR-200 "pretzel" device. The discussion also highlights how advances in molecular profiling are reshaping care strategies.This episode underscores the urgent need for clearer guidelines and continued innovation to improve outcomes and quality of life for patients with this nuanced disease subtype. --- TIMESTAMPS 00:00 - Introduction02:03 - Defining Intermediate Risk Bladder Cancer06:12 - Intravesical Therapy Options08:47 - Quality of Life and Patient Counseling10:18 - New Treatments on the Horizon12:56 - Practical Tips for TURBT Recovery17:03 - In-Office Procedure Management21:38 - Managing Symptoms and Quality of Life31:50 - A Note on Smoking Cessation33:37 - Conclusion and Future Directions
Vaginal estrogen is not the enemy. Outdated data is. In this crossover episode of the BackTable Urology and OBGYN podcasts, Dr. Suzette Sutherland and Dr. Yahir Santiago-Lastra delve into the persistent challenges and ongoing advocacy efforts surrounding the FDA's black box warning on vaginal estrogen. --- SYNPOSIS They explore the historical context and far-reaching influence of the 1990s Women's Health Initiative (WHI) study, asserting that its misinterpretation continues to shape misconceptions and hinder effective menopause care. The discussion highlights recent data refuting the risks associated with vaginal estrogen therapies and underscores the urgent need for updated, evidence-based guidelines to support women throughout menopause. Dr. Santiago-Lastra also draws attention to gender-based inequities in hormone treatment, the robust evidence contradicting the current black box warning, and the multi-faceted advocacy required to bring about change. This episode is part of a broader series focused on various aspects of menopause. --- TIMESTAMPS 00:00 - Introduction02:01 - Menopause Series Overview03:55 - History of the Black Box Warning on Estrogen07:26 - Understanding the Black Box Warning12:11 - The Citizen's Petition and FDA Process18:11 - Gender Inequity in Medical Treatment22:45 - Factors Resulting in Gender Inequity29:02 - Genital Urinary Syndrome of Menopause (GSM)29:32 - Benefits of Vaginal Estrogen33:33 - Legislative Advocacy and Medicare34:43 - Professional and Patient Advocacy36:35 - Challenges and Progress in Label Change43:35 - Historical Context and Gender Equity45:07 - Recap and Future Directions
We break down Wittle Defender, Habby's latest departure from the mass market, blending deep meta, squad RPG mechanics, and a relentless gacha system. This is not another Survivor IO. It is a meta monster built for hardcore RPG fans, multi-layered progression, gear grind, rune systems, and dozens of monetization hooks. But is it too deep for global scale?What's inside:Meta Gone WildGacha and ProgressionMore Modes, More MonetizationDeep automation and idle mechanics Ad Revenue ShrinksUA and Creative: Focused on Asia, with heavy use of fake gameplay, static images, and Rush Royale or Top Heroes clones for Facebook and TikTok ads. Playable ads exist but are rare.Key Takeaway:Wittle Defender marks Habby's pivot away from broad hybrid monetization. The focus now is on deep spend, multi-layered progression, and gacha depth for a smaller, more hardcore player base. Ad revenue is down, IAP is up, and the US is no longer the top target.Get our MERCH NOW: 25gamers.com/shop--------------------------------------PVX Partners offers non-dilutive funding for game developers.Go to: https://pvxpartners.com/They can help you access the most effective form of growth capital once you have the metrics to back it.- Scale fast- Keep your shares- Drawdown only as needed- Have PvX take downside risk alongside you+ Work with a team entirely made up of ex-gaming operators and investors---------------------------------------Vibe. Vibe is the leading Streaming TV ad platform for small and medium-sized businesses looking for actionable advertising campaign performance.https://www.vibe.co/---------------------------------------For an ever-growing number of game developers, this means that now is the perfect time to invest in monetizing direct-to-consumer at scale.Our sponsor FastSpring:Has delivered D2C at scale for over 20 yearsThey power top mobile publishers around the worldLaunch a new webstore, replace an existing D2C vendor, or add a redundant D2C vendor at fastspring.gg.---------------------------------------This is no BS gaming podcast 2.5 gamers session. Sharing actionable insights, dropping knowledge from our day-to-day User Acquisition, Game Design, and Ad monetization jobs. We are definitely not discussing the latest industry news, but having so much fun! Let's not forget this is a 4 a.m. conference discussion vibe, so let's not take it too seriously.Panelists: Jakub Remiar, Felix Braberg, Matej LancaricYoutube: https://youtu.be/lg023xHkCUkJoin our slack channel here: https://join.slack.com/t/two-and-half-gamers/shared_invite/zt-2um8eguhf-c~H9idcxM271mnPzdWbipgChapters00:00 Introduction and Host Dynamics02:49 Sailing Adventures and Job Interviews04:06 Whittle Defender Game Overview07:19 Game Mechanics and Progression Systems11:22 Monetization Strategies and User Experience14:22 Gameplay Modes and Challenges18:17 Character Skills and Randomization Mechanics25:18 Final Thoughts and Game Depth25:42 Character Dynamics and Game Mechanics28:36 Game Depth and Player Engagement29:52 Market Positioning and Audience Targeting34:15 Revenue Insights and Market Performance40:15 Monetization Strategies and Future Directions44:06 Game Mechanics and Trends46:13 Marketing Strategies in Gaming51:18 Investment and Development in the Gaming Industry56:14 Future Directions for Game Studios---------------------------------------Matej LancaricUser Acquisition & Creatives Consultanthttps://lancaric.meFelix BrabergAd monetization consultanthttps://www.felixbraberg.comJakub RemiarGame design consultanthttps://www.linkedin.com/in/jakubremiarPlease share the podcast with your industry friends, dogs & cats. Especially cats! They love it!Hit the Subscribe button on YouTube, Spotify, and Apple!Please share feedback and comments - matej@lancaric.me
Text Dr. Lenz any feedback or questions This detailed podcast episode delves into the findings of a study on Chronic Fatigue Syndrome (CFS) using functional MRI and immune system analysis. The speaker explains the technology behind functional MRI and what it revealed about brain activity, specifically in the parietal temporal junction, which showed hypoactivity in CFS patients. The discussion extends to immune abnormalities, highlighting immune cell exhaustion, and hypothesizing links to persistent infections. The episode emphasizes the need for interdisciplinary, evidence-based approaches to treating these 'invisible' illnesses and calls for more integrated, patient-centric research. Other discussed topics include the limitations of current medical specialization and the need for generalist knowledge, the role of gut microbiome, and potential lessons from oncology on immune checkpoints.00:00 Introduction to Functional MRI01:48 Understanding Functional MRI Findings04:08 Immune System Insights04:54 Cancer Research and Immune Exhaustion09:01 Genetic Susceptibility and Long COVID10:33 Holistic Approach to Medicine13:34 Challenges in Treating CFS and Fibromyalgia15:38 Future Directions in Research22:40 Gut Microbiome and Immune Response25:41 Neurodivergence and Immune System29:25 Conclusion and Final Thoughts International Conference on ADHD in November 2025 where Dr. Lenz will be one of the speakers. Support the showWhen I started this podcast—and the book that came before it—I had my patients in mind. Office visits are short, but understanding complex, often misunderstood conditions like fibromyalgia takes time. That's why I created this space: to offer education, validation, and hope. If you've been told fibromyalgia “isn't real” or that it's “all in your head,” know this—I see you. I believe you. You're not alone. This podcast aims to affirm your experience and explain the science behind it. Whether you live with fibromyalgia, care for someone who does, or are a healthcare professional looking to better support patients, you'll find trusted, evidence-based insights here, drawn from my 28+ years as an MD. Please remember to talk with your doctor about your symptoms and care. This content doesn't replace personal medical advice.* ...
Counseling patients with intermediate-risk non-muscle invasive bladder cancer can be complex, with a wide range of treatment options and care pathways. In this episode of BackTable Urology, urologic oncologists Dr. Ruchika Talwar and Dr. Kelly Bree explore how to approach this challenge with clarity and compassion. --- This podcast is supported by an educational grant from UroGen Pharma. --- SYNPOSIS They emphasize a shift toward patient-centered, less aggressive treatment strategies, highlighting the importance of quality of life in clinical decision-making. The discussion includes risk stratification, the use of intravesical gemcitabine, and ongoing clinical trials. Dr. Bree also offers actionable tips for optimizing patient preparation and recovery. This episode underscores the growing importance of listening to patient voices to shape future standards of care. --- TIMESTAMPS 00:00 - Introduction and Overview02:09 - Risk Stratification and Treatment Approaches06:12 - Intravesical Therapy Options08:47 - Quality of Life and Patient Counseling12:56 - Practical Tips for TURBT Recovery17:03 - In-Office Procedures and Patient Management21:23 - Resources and Support for Patients24:13 - Future Directions and Final Thoughts --- RESOURCES Society of Urologic Oncologyhttps://suonet.org/home.aspx
In this conversation, Rob Craven, founder of Scale Passion, shares his journey of discovering personal purpose and how it intertwines with business success. He discusses the importance of intentionality in leadership, the evolution of his company, and the significance of writing and reflection in understanding one's purpose. The dialogue emphasizes the need for personal happiness in business and the concept of work-life synergy, advocating for a life where passion and work are seamlessly integrated. Rob also touches on the challenges of navigating liminal spaces in life and business, encouraging listeners to embrace change and growth. In this conversation, Gage and Rob Craven explore the significance of rest and reflection in personal and professional growth, emphasizing the importance of purpose-driven businesses in today's economy. They discuss the evolution of capitalism from a shareholder-focused model to a more inclusive stakeholder approach, highlighting the need for businesses to integrate purpose and impact into their operations. The dialogue also touches on the challenges faced by small businesses and the potential for a shift towards regenerative business models that prioritize community and environmental well-being. Rob shares insights from his book, 'Scale Passion,' and his vision for a better world where fulfillment and purpose drive positive change. Takeaways:Rob Craven is the founder of Scale Passion and author of a purpose-driven business blueprint.Personal purpose and business purpose should be connected for fulfillment.Rob's early life experiences shaped his values of being bold and making a difference.The journey to discovering purpose is often iterative and requires reflection.Personal happiness is crucial for business success; leaders must prioritize it.Work-life synergy is more beneficial than work-life balance.Writing helps clarify thoughts and solidify understanding of purpose.Intentional living involves making the unconscious conscious.Embracing fear can lead to meaningful growth and outcomes.Navigating liminal spaces can be challenging but is part of the journey. Rest and reflection are crucial for personal growth.Purpose-driven businesses can create significant impact.Capitalism is evolving towards a more inclusive model.3.0 businesses often outperform 2.0 businesses.The marketplace is shifting towards sustainability and purpose.Integrating impact with business growth is essential.Small businesses need support to thrive in today's economy.Provocative dialogue can lead to meaningful conversations.A better world is one where everyone is aligned with their purpose.Energy from purpose can transform communities and businesses. Sound Bites:"I exist to scale impact.""It's a continuous journey of becoming."“What's really fascinating is when you start getting very intentional and making the unconscious conscious, the decisions you make become glaring in whether they're aligned with purpose or not.""Go where the water wants to flow. Trust the Universe and your purpose.”“The scarier it is, the more the outcome will be meaningful.""Don't settle for a J-O-B.""I believe business is the hope for the world""You can do impact work and grow a business and have profit.”"How do we make this transition in a way that sets us up for growth, economic prosperity and impact? And so I just want to keep banging the drum that it doesn't have to be separate." Links:Rob Craven on LinkedIn - https://www.linkedin.com/in/robertucraven/ScalePassion - https://scalepassion.com/ScalePassion on LinkedIn - https://www.linkedin.com/company/scalepassion/ScalePassion Book - https://book.scalepassion.com/#orderRadiate Purpose Workbook - https://scalepassion.com/radiate-purpose…Brands for a Better World Episode Archive - http://brandsforabetterworld.com/Brands for a Better World on LinkedIn - https://www.linkedin.com/company/brand-for-a-better-world/Modern Species - https://modernspecies.com/Modern Species on LinkedIn - https://www.linkedin.com/company/modern-species/Gage Mitchell on LinkedIn - https://www.linkedin.com/in/gagemitchell/…Print Magazine Design Podcasts - https://www.printmag.com/categories/printcast/…Heritage Radio Network - https://heritageradionetwork.org/Heritage Radio Network on LinkedIn - https://www.linkedin.com/company/heritage-radio-network/posts/Heritage Radio Network on Facebook - https://www.facebook.com/HeritageRadioNetworkHeritage Radio Network on X - https://x.com/Heritage_RadioHeritage Radio Network on Instagram - https://www.instagram.com/heritage_radio/Heritage Radio Network on Youtube - https://www.youtube.com/@heritage_radioChapters:03:00 - Introduction to Purpose-Driven Business06:08 -Rob's Origin Story and Early Influences08:52 - The Evolution of Purpose and Leadership11:54 - Personal Happiness and Business Success15:00 - Work-Life Synergy vs. Balance17:49 - The Power of Writing and Reflection20:53 - Intentional Purpose and Business Planning23:57 - The Journey of Scale Passion26:59 - Embracing Change and Growth30:02 - Navigating the Liminal Space31:02 - The Importance of Rest and Reflection32:54 - Scaling Purpose Through Business35:07 - The Role of Purpose-Driven Businesses37:06 - Capitalism 2.0 vs. 3.039:00 - Defining Capitalism's Evolution43:06 - The Shift Towards Regenerative Business Models45:11 - Supporting Small Businesses and Startups49:07 - Personal Insights and Future Directions
This conversation focuses on the implementation of a cold blood protocol for military training, emphasizing the importance of whole blood transfusions in preventing deaths from hemorrhagic shock. The discussion covers the logistics of blood availability, the challenges of storage and transportation, and the establishment of a pilot program for blood donation. The speakers highlight the collaboration with blood banks and the regulatory hurdles faced, while also outlining future directions for expanding the program to enhance medical support during training events.TakeawaysHemorrhage is the leading cause of preventable death on the battlefield.Whole blood is recognized as the superior resuscitation fluid.Logistics and availability of blood during training are critical issues.Cold blood storage can be effectively implemented in training environments.A pilot program for blood donation has been established to support training needs.Collaboration with blood banks is essential for successful blood storage and use.Regulatory challenges complicate blood storage and transportation.Training medics to use cold stored blood is a priority.Future expansion of the program is necessary to meet training demands.Increased knowledge of blood protocols enhances medic preparedness.Chapters00:00 Introduction to Cold Blood Protocol03:02 Understanding Hemorrhagic Shock and Blood Transfusion06:07 Logistics of Blood Availability in Training08:55 Implementing Cold Blood Storage in Training Environments12:11 Pilot Program for Blood Donation and Storage14:50 Collaboration with Blood Banks and Regulatory Challenges18:14 Future Directions and Program Expansion20:58 Conclusion and Key TakeawaysThank you to Delta Development Team for in part, sponsoring this podcast.deltadevteam.comFor more content, go to www.prolongedfieldcare.orgConsider supporting us: patreon.com/ProlongedFieldCareCollective or www.lobocoffeeco.com/product-page/prolonged-field-care
In this conversation, the speakers explore the detrimental effects of busyness on spiritual connection and the importance of cultivating communion with God amidst a technology-driven world. They discuss practical steps to reduce distractions, the significance of experiencing God's presence, and the healing that comes from intimacy with Christ. The conversation emphasizes the need for quiet environments and the journey towards finding belovedness in a busy life. In this conversation, the speakers explore the importance of reconnecting with one's inner self, the journey of healing from father and mother wounds, and the significance of community in recovery. They discuss the need for a deeper union with God and the role of belovedness in overcoming sexual compulsions. The conversation emphasizes the necessity of slowing down in a fast-paced world and the healing power of love and connection in parenting and personal growth. Got a Question? It Could Be on the Podcast! Submit It Through This Form Find Out More About My DeepClean Recovery Program Here Get A Free Copy of The Last Relapse, A Blueprint For Recovery Watch Sathiya on Youtube For More Content Like This Download the app "One Minute Pause" 00:00 The Impact of Busyness on Spiritual Connection 03:00 Navigating Technology and Distraction 05:50 Cultivating Communion with God 09:01 Experiencing God's Presence 11:56 Healing Through Intimacy with Christ 14:57 The Role of Environment in Spiritual Practices 17:55 Finding Belovedness in a Busy World 29:08 Reconnecting with the Inner Self 32:04 Cultivating Union with God 33:13 The Journey of Writing and Healing 36:19 Understanding and Empathy in Spirituality 37:17 Healing from Father and Mother Wounds 39:15 The Role of Belovedness in Recovery 42:12 The Illusion of Quick Fixes 44:44 Navigating Father Wounds and Sexual Issues 49:07 Fatherhood and Healing Childhood Trauma 52:30 The Importance of Love in Parenting 53:00 Community and Connection for Men 56:34 Future Directions for Wild at Heart