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Send us a textDarius Shapre is a returning guest on our show! Be sure to check out his first appearance on episode 636 of Boundless Body Radio! Darius Sharpe has an extensive 22-year career in healthcare, including 3 years as an EMT, 13 years as a paramedic, and 6 years as an ER nurse. He is a dedicated fitness and health enthusiast, regularly participating in endurance events such as Spartan Races and marathons.Despite maintaining good health, he was diagnosed as pre-diabetic some years ago and discovered a CAC score of 44 at the age of 39 in the summer of 2023. Since then, he has devoted significant effort to understanding the reasons behind these health issues and determining the appropriate course of action.Darius has become increasingly dissatisfied with the current medical system and has questioned why doctors do not prescribe nutrition and exercise plans to patients instead of solely relying on medication. Drawing on his medical background, Darius has delved deeply into the realms of nutrition, metabolic illness, diabetes, cardiac disease, and autoimmunity.He continues to educate himself daily and has been amazed to discover in the literature how many of these conditions can be prevented, reversed, or improved through simple dietary changes.Find Darius at-IG- @murse_dariusTW- @MurseDariusFB- Darius Sharpehttps://cosci.org/Find Boundless Body at- myboundlessbody.com Book a session with us here!
Discover the spiritual and physical keys to overcoming obesity, chronic illness, and sugar addiction. Dr. Jean Guy reveals how detoxing your body in alignment with God's design can restore health and freedom. Purchase Kathy's book Healed at Last – Overcome Sickness to Receive your Physical Healing on Amazon https://a.co/d/6a6mt8w or at: https://www.kathydegrawministries.org/healed-at-last/ Purchase Anointing Oil with a prayer cloth that Kathy has personally mixed and prayed over on Kathy's Website or Amazon. Order anointing oil by Kathy on Amazon look for her brand here https://amzn.to/3PC6l3R or Kathy DeGraw Ministries https://www.kathydegrawministries.org/product-category/oils/ Training, Mentorship and Deliverance! Personal coaching, deliverance, e-courses, training for ministry, and mentorships! https://www.kathydegrawministries.org/training/# In this powerful and eye-opening episode, Dr. Jean Guy uncovers the spiritual and biological roots of obesity and chronic disease—revealing why detoxification is a critical step toward reclaiming vibrant health. With over 25 years of experience in nutrition and chiropractic care, he explains how hidden sugars, toxic buildup, and processed foods silently sabotage your health—even under the label of “healthy.” You'll learn how toxins stored in fat cells contribute to weight gain and how your liver, gut, and gallbladder must be supported for true transformation. This is not just about losing weight—it's about breaking the spiritual bondage that comes from unhealthy patterns and learning how to hear the Holy Spirit in your health decisions. Dr. Jean Guy lays out a practical roadmap that includes clean hydration, infrared sauna use, green juicing, and identifying what your unique body truly needs. Most importantly, you'll be empowered by the truth that God desires for His people to walk in wholeness—spirit, soul, and body. If you're tired of worldly health trends and are ready to embrace a Kingdom approach to healing, this conversation will ignite your journey. #detox #obesity #christianhealth #sugaraddiction #healingjourney **Connect with Dr. Jean at https://www.gileadhealingcenter.com/ **Connect with Us** - Website: https://www.kathydegrawministries.org/ - Facebook: https://www.facebook.com/kathydegraw/ - Instagram: https://www.instagram.com/kathydegraw/ Podcast - Subscribe to our YouTube channel and listen to Kathy's Podcast called Prophetic Spiritual Warfare, or on Spotify at https://open.spotify.com/show/3mYPPkP28xqcTzdeoucJZu or Apple podcasts at https://podcasts.apple.com/us/podcast/prophetic-spiritual-warfare/id1474710499 **Recommended Resources:** - Receive a free prayer pdf on Warfare Prayer Declarations at https://kathydegrawministries.org/declarations-download - Kathy's training, mentoring and e-courses on Spiritual Warfare, Deliverance and the Prophetic: https://training.kathydegrawministries.org/ - Healed At Last ~ Overcome Sickness and Receive your Physical Healing: https://www.kathydegrawministries.org/healed-at-last/ - Mind Battles – Root Out Mental Triggers to Release Peace!: https://www.kathydegrawministries.org/product/mind-battles-pre-order-available-january-2023/ -Kathy has several books available on Amazon or kathydegrawministries.org **Support Kathy DeGraw Ministries:** - Give a one-time love offering or consider partnering with us for $15, $35, $75 or any amount! Every dollar helps us help others! - Website: https://www.kathydegrawministries.org/donate/ - CashApp $KDMGLORY - Venmo @KD-Ministries - Paypal.me/KDeGrawMinistries or donate to email admin@degrawministries.org - Mail a check to: Kathy DeGraw Ministries ~ PO Box 65 ~ Grandville MI 49468
Today we're talking about obesity medication. Did you know that over 200 illnesses are linked to unhealthy weight gain? It's no surprise that combatting obesity has become a major focus of modern medical research. In recent years, this research has led to a new generation of weight-loss medications that are delivering dramatic results. But are these drugs truly revolutionary or just too good to be true? One thing is certain - people have a lot of questions. Today, I'm joined by Dr. Lou Aronne to help us separate the hype from the hard facts.
TakeawaysThe study examines the overlap between clinical and anthropometric obesity.Anthropometric measures include waist circumference, waist-to-hip ratio, and BMI.Challenges exist in applying the Lancet Commission's definitions in clinical practice.Metabolically healthy obesity is a debated topic in obesity research.The study highlights the importance of data from the All of Us Research Program.There is a significant prevalence of preclinical obesity in individuals with normal BMI.The classification of obesity may need to shift focus towards overweight individuals.The study's findings suggest a need for more nuanced definitions of obesity-related diseases.Future research will explore the transition from preclinical to clinical obesity.The conversation emphasizes the importance of real-world data in understanding obesity.Click here to see the studyFollow Dr. Yao on X hereFollow Dr. Blaha on X here Click here to join Dr. Spencer's online clinic
Dr. Hoffman continues his conversation with Dr. Nina Teicholz, a PhD nutritionist, founder of the Nutrition Coalition, and author of "The Big Fat Surprise".
The Protein Paradigm: Redefining Dietary Guidelines with Dr. Nina Teicholz, a PhD nutritionist, founder of the Nutrition Coalition, and author of "The Big Fat Surprise". The discussion focuses on controversies around dietary guidelines, particularly the misrepresentation of low-fat diets and the critical role of protein in optimal health. Dr. Teicholz addresses the flaws in the US Dietary Guidelines, highlights the impact of institutionalized groupthink on nutrition science, and argues for the reassessment of protein recommendations and the demonization of saturated fats. She also examines the challenges and influence of food industry conflicts on public health policies and shares insights on the potential for meaningful reform under the current administration.
In this episode, we talk about one of the most popular medications on the market right now - GLP1 receptor agonists - with Dr. Greg Gatchell, a physician boarded in Family Medicine, Lifestyle Medicine, and Obesity as well as a certified health coach. We unpack the real science of weight gain, hormones, and the role of hormones like insulin and GLP-1. We break down how GLP-1 medications work, who they're best suited for, and the common myths surrounding these drugs. Together, we explore why weight loss is about more than willpower alone, the importance of lifestyle support even when using medications, and how to make informed choices about long-term obesity management. Whether you're considering a GLP-1 prescription, supporting a loved one, or simply curious about how modern medicine tackles obesity, this episode will give you practical, compassionate insights you can use today!Connect with Dr. Greg Gatchell, DO:LinkedInConnect with Dr. Jonar, MD: Book Your Free Health Coaching Consult with Dr. Jonar4 Truth Health CoachingInstagramFacebookLinkedin ThreadsDr. Jonar Website HOW CAN I SUPPORT THIS PODCAST?Download, Listen, Subscribe, Rate & Review: Glass Half Healthy on Apple Podcast Glass Half Healthy on SpotifyTell Your Family & Friends! And Share Online!Thanks to Dan Olfato for production help and to StockSounds for the music. And to YOU! Thank you for listening!Disclaimer:This podcast is intended for educational purposes only and isn't medical advice so please talk to your primary physician for that. In addition, the views and opinions expressed by me are my own and not that of my former, current or future employer. This also applies to my guests. Finally, we do our best to make every effort to relay correct information, but don't guarantee its accuracy. Thank you for listening.
In this episode, Therese Markow interviews Dr. Shaina Stacy about her studies on cancer risks in children depending upon the body mass index (BMI) of their mothers before and during pregnancy. Dr. Stacy explains how she obtained a sample of nearly 2 million mother-child pairs in the state of Pennsylvania, the largest sample size ever for such a study. They discuss how children of women with a BMI of over 30 when pregnant had a significantly higher risk of cancers compared to children of lean mothers. This was notable for leukemia in children under 5, especially acute lymphoblastic leukemia (ALL). The mechanism underlying the increased risk is not yet known. Key Takeaways: Maternal obesity before and during pregnancy increases the risk of cancers in children under 5 years of age. The risk of leukemia, especially acute lymphoblastic leukemia or ALL, is the greatest. Children of white, educated women, if obese during pregnancy, have the highest risk. Transgenerational effects of obesity are becoming more apparent. "We found that children born to mothers in our highest BMI category had over 30% higher risk of developing any type of childhood cancer." — Dr. Shaina Stacy Connect with Dr. Shaina Stacy: Scientific American Blog Post: Cancer Prevention Should Start before Birth - https://blogs.scientificamerican.com/observations/cancer-prevention-should-start-before-birth/ LinkedIn: https://www.linkedin.com/in/shaina-stacy-0664962b/ Connect with Therese: Website: www.criticallyspeaking.net Threads: @critically_speaking Email: theresemarkow@criticallyspeaking.net Audio production by Turnkey Podcast Productions. You're the expert. Your podcast will prove it.
Want to know how fasting can boost your health, change how you think about food, and reset your body? In this episode of Mark Bell's Power Project Podcast, Mark Bell, Nsima Inyang, and guest Joseph Everett dive deep into the health benefits of fasting and share why it's more than just skipping meals.Learn how fasting lowers IGF-1 levels, improves brain health, and even changes hunger patterns over time. They break down the connection between fasting, physical endurance, and how your food choices impact digestion, inflammation, and long-term energy. Plus, hear thoughts on the carnivore diet, lab-grown meat, and biohacking methods that could redefine your fitness goals.Follow Joseph on IG: https://www.instagram.com/josepheverett.wilSpecial perks for our listeners below!
This week on Fat Science, Dr. Emily Cooper, Andrea Taylor, and Mark Wright break down the essentials of a true metabolic workup. This episode moves beyond social media diet trends and digs into the science behind comprehensive lab panels, what they measure, and why they matter for your whole-body health. Dr. Cooper explains how to interpret common and advanced metabolic markers—like blood sugar, insulin, cholesterol, hormone levels, and more—while Andrea and Mark share personal insights into the power of understanding your metabolic baseline. If you're concerned about weight, diabetes, or just want to know your numbers, this episode gives you the knowledge to talk confidently with your healthcare provider.Key Takeaways:A whole-body metabolic approach goes beyond just weight or blood pressure—comprehensive lab work (plus family history) is essential to uncover risks or dysfunction early.Standard blood panels provide useful clues (glucose, cholesterol, liver, kidney, blood pressure), but advanced tests (A1C, lipid particles, hormone levels, inflammation markers) round out the picture.Metabolic dysfunction is driven by factors far deeper than calories in/out—dieting and under-fueling can actually weaken metabolism over time.Medication for metabolic health is not a failure; it's a science-backed intervention. Early and accurate testing allows for better, evidence-based treatment.Don't ignore “borderline” results—addressing issues early is easier and more effective than trying to reverse advanced dysfunction later.Personal Stories & Practical Advice:Andrea recounts her life-changing journey from endless dieting to real answers through complete metabolic testing and individualized treatment.Mark highlights the need for patients to advocate for themselves and ask for more than just the standard panel at annual exams.References:Diet Failure Rate• Mann, T., et al. (2007). "Medicare's search for effective obesity treatments: diets are not the answer." American Psychologist, 62(3), 220-233• Anderson, J. W., et al. (2001). "Long-term weight-loss maintenance: a meta-analysis of US studies." American Journal of Clinical Nutrition, 74(5), 579-584Persistent Metabolic Adaptation• Fothergill, E., et al. (2016). "Persistent metabolic adaptation 6 years after 'The Biggest Loser' competition." Obesity, 24(8), 1612-1619• Rosenbaum, M., & Leibel, R. L. (2010). "Adaptive thermogenesis in humans." International Journal of Obesity, 34(S1), S47-S55Long-Term Hormonal Disruption • Sumithran, P., et al. (2011). "Long-term persistence of hormonal adaptations to weight loss." New England Journal of Medicine, 365(17), 1597-1604• Rosenbaum, M., et al. (2005). "Low-dose leptin reverses skeletal muscle, autonomic, and neuroendocrine adaptations to maintenance of reduced weight." Journal of Clinical Investigation, 115, 3579-3586Weight Cycling Cardiovascular Risks• Montani, J. P., et al. (2006). "Weight cycling during growth and beyond as a risk factor for later cardiovascular diseases: the 'repeated overshoot' theory." International Journal of Obesity, 30(S4), S58-S66Resources:Connect with Dr. Emily Cooper on LinkedInConnect with Mark Wright on LinkedInConnect with Andrea Taylor on InstagramFat Science is a podcast on a mission to explain where our fat really comes from and why it won't go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn't a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.If you have a question for Dr. Cooper, a show idea, feedback, or just want to connect, email us at info@diabesityinstitute.org or dr.c@fatsciencepodcast.comScience is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org
We've reached a point where complaining about obesity gets you applause, not advice.Say “I'm struggling to lose weight”?
Send us a textChris Spath is a living example of what diet and lifestyle can do to impact health and disease.His spouse, Laura Spath, is a multiple guest on our show, so be sure to check out her appearances on episodes 169 and 308 of Boundless Body Radio!When a serious health scare inspired Chris to take ownership of his health, he decided to try the carnivore diet, and soon after, Laura joined him. Laura and Chris ended up losing a combined 250 pounds due to their joint adoption of the carnivore diet!Today they share their inspirational story with us and let us know how they achieved such remarkable weight loss. Laura and Chris focus on feeding their kiddos high protein meals, and keeping grains, sugars, and seed oils out of their diet. He's spent almost a decade eating a carnivore diet, losing over 100 pounds, reversing type-2 diabetes and numerous other health ailments. Chris is a stay-at-home dad, who spends his days homeschooling his 2 children and supporting Laura with her social media channels spreading the message of carnivore.At 50 years old, Chris trains BJJ along with his kids, hits the gym daily, and maintains an active lifestyle.Find Chris at-IG- @chrisjspathFind Laura at- IG- lauraespath YT- Laura Spath The Cutting Against The Grain PodcastFind Boundless Body at- myboundlessbody.com Book a session with us here!
Happy Friday! Here's a quick look at our top local stories for Friday, June 27. Have a great day and weekened. Thanks for listening and reading local!
Jamaal Bowman blames heart disease, diabetes and Obesity on racism, and the panel doesn't know how to react to that statement. Visit the Howie Carr Radio Network website to access columns, podcasts, and other exclusive content.
Fixing obesity with a Fitbit. To advertise on our podcast, please reach out to sales@advertisecast.com or visit https://www.advertisecast.com/TheJeffWardShow
What's really causing America's obesity epidemic? In this special debate episode of The Metabolic Link, two leading voices in metabolic health square off: Dr. Richard Johnson, renowned for his research on fructose metabolism, and Dr. Layne Norton, a PhD in nutritional sciences and expert on the energy balance model. Moderated by host Dr. Dominic D'Agostino, the discussion dives deep into the biological roots of obesity, the relevance of sugar-sweetened beverages, the role of leptin and uric acid, and whether it's fructose or calories that are driving the crisis. Despite their differing perspectives, both experts agree on one critical point—our modern food environment is fueling metabolic dysfunction on a massive scale. This is one of the most nuanced and constructive conversations you'll hear on the topic of obesity science.References submitted by both guests can be found here!For more exclusive interviews and presentations with Dr. Johnson and Dr. Norton along with 100s of other videos on metabolic health and therapy, ad-free private episodes of The Metabolic Link, and to earn CMEs visit our member medical education platform: https://membership.metabolicinitiative.comSpecial thanks to the sponsors of this episode:✅ Genova Connect – Get 15% off any test kit with code METABOLICLINK here✅ iRestore – Get a huge discount when you use the code METABOLICLINK here✅ Fatty15 – Get 15% off a 90-day Starter Kit with code METABOLICLINK hereLearn more about Dr. Layne NortonLearn more about Dr. Richard JohnsonIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.
What if you built a billion-dollar fitness empire — and then had the courage to tear it down for something better?In this powerful episode of The Big Silence, Karena Dawn sits down with Carl Daikeler, founder of Beachbody (now known as BODi), the man behind household names like P90X, Insanity, Shakeology, and Morning Meltdown 100. But this isn't just a story of success — it's a brutally honest look at motivation, body image, entrepreneurship, and the daily mental work it takes to keep going when things get hard.From growing up backstage in a Pennsylvania theater to running a global health brand with over a million users, Carl shares the emotional, mental, and spiritual tools that have kept him moving forward. You'll hear about the behind-the-scenes challenges of rebranding from Beachbody to BODi, the surprising role Broadway played in his journey, and his no-BS take on fitness fads, GLP-1s, and tech obsession.Are We Measuring Fitness Wrong?Carl and Karena unpack the myths of the wellness industry — including why the best fitness “tech” is already inside you.(00:01:50) The Birth of Beachbody: A Brand Built for People Who Hate Working OutCarl created Beachbody to help impatient, goal-oriented people get consistent without loving fitness.Success didn't come from being a guru — it came from being a relatable customer.“Day one to day done”: Programs need structure, not endless motivation.Community was always the secret sauce: message boards before social media.(00:09:30) From Infomercials to Shakeology to MLM: Lessons in IterationP90X's breakout success during the 2008 recession changed the game.Word-of-mouth became the strategy behind the multi-level model.“The customer who solves their lifestyle problem deserves the reward.”Carl defends the ethics and intent behind Beachbody's direct sales shift — and why it had to evolve.(00:15:43) GLP-1s, Obesity, and What the Industry Is Getting WrongCarl's stance: These meds are tools — but not solutions without resistance training and nutrition.“Lifestyle change is so hard… but if you can monetize your consistency? That's powerful.”The secret pill culture from the ‘90s is back — but smarter wellness demands a full-picture approach.Fitness tech is great — until it overrides your intuition.(00:18:46) Carl's Morning Routine: Cold Plunges, Kefir & Spinach ShakesWake-up time: ~5–6 AM, no alarm.Lemon water + ginger + olive oil + kefir shot = ritual jumpstart.3.5-minute cold plunge followed by a 45-min workout.Weekend DIY meal prep keeps him on track — and surprisingly, he hates vegetables.(00:24:00) The Power of Persistence: What's Made Him Relentless“It's about the objective — even if it's just influencing one person.”Reads company case studies and biographies to stay grounded.Avoids victim mindset: “Self-pity invites fear, and fear kills creativity.”Expansion, not perfection, keeps him engaged after 27 years.(00:28:34) Why He Changed “Beachbody” to “BODi” — And Faced the BacklashBeachbody = outdated ideals; BODi = well-being and “health esteem.Carl wanted his kids to grow up with a healthier message around body image.Despite board resistance, he pushed the rebrand through for long-term values.“Do I want to be known for six-pack abs… or for helping people love themselves enough to take care of themselves?” (00:33:32) Where Fitness Needs to Go: Simple, Sustainable, and...
Robert F. Kennedy Jr. testified in front of the House Committee on Energy and Commerce Tuesday, where Democrats confronted the health secretary on hot button issues ranging from his recent overhaul over the CDC's Advisory Committee on Immunization Practices (ACIP) committee, Kennedy's recently published—and error-ridden—MAHA report, and his threat to ban government scientists from publishing in certain medical journals. Meanwhile, at the FDA, the mass exodus of senior leadership continues. On Monday, Jacqueline Corrigan-Curay, acting head of the Center for Drug Evaluation and Research (CDER), announced her retirement as of July. This follows the ouster of Nicole Verdun—the wildly popular director of the FDA's Office of Therapeutic Products—and her deputy, Rachael Anatol. Their involuntary departure sent shock waves through the biopharma industry, as Verdun had been considered a stabilizing force at the rapidly reshaping agency. Speaking of the revamped ACIP, the new panel will meet for the first time Wednesday and Thursday to discuss COVID-19 vaccine safety, maternal and pediatric RSV vaccines and more, as experts question the experience and anti-vaccine views of some of Kennedy's recently appointed members and others express concern about the potential politicization of the committee. On the clinical front, Eli Lilly, Novo Nordisk and others presented new data from their next-generation obesity programs at the American Diabetes Association's 85th Scientific Congress. After failing to impress investors—and meet its own high expectations—with CagriSema, Novo sought to reassure investors by touting a safety profile “in line with the GLP1-RA class,” and Eli Lilly reported that bimagrumab, when used alongside Novo's Wegovy, led to additional weight loss while also preserving muscle mass. Finally, we recap BIO2025, where Jef Akst, Lori Ellis and Heather McKenzie moderated panels on cell and gene therapy, cybersecurity and AI, and accelerating market entry for rare disease treatments. Relevant to the latter discussion, congressional Republicans dropped the Orphan Cures Act from their version of President Donald Trump's “One Big Beautiful Bill Act,” and congresspeople, including Rep. Gus Bilirakis (R-Fla.) at Tuesday's hearing asked Kennedy to commit to supporting the priority review program for rare pediatric diseases, which expired at the end of last year.
In this episode, Therese Markow and Dr. Cheryl Hawkes discuss the increasing scientific evidence that maternal obesity affects the developing fetal brain. While many of the effects manifest early, in infant temperament and childhood cognitive (IQ) decrements, other effects do not show up until years later, in adult psychiatric and neurodegenerative problems. The physical bases for these changes in fetal brains are also clearly evidenced in laboratory model systems, such as mice, where the maternal diets can be controlled, and the offspring not only can be given behavioral tests, but their brains can be dissected to reveal the changes in the blood vessels caused by obese mothers. Key Takeaways: Children born to obese mothers have lower IQs and poorer motor, spatial, and verbal skills. Mice and rodents have similar brain development to humans, which is why rodent study models are so beneficial to science. Brain maturation takes many years. Your brain is fully formed at birth, but continues to mature and change into your mid-twenties. "Because of the rise in obesity globally, a lot of people have started to look, rather than looking at famine…, to now shift our attention to looking at the long-term effects of obesity because 30% of women around the world, over the age of 18, are now considered to be obese." — Dr. Cheryl Hawkes Connect with Dr. Cheryl Hawkes: Lancaster University Profile: Dr. Cheryl Hawkes Connect with Therese: Website: www.criticallyspeaking.net Threads: @critically_speaking Email: theresemarkow@criticallyspeaking.net Audio production by Turnkey Podcast Productions. You're the expert. Your podcast will prove it.
Listen in as Joseph Kim, MD, MPH, MBA; Manish Shah, MD; Martha Grugel, MA, discuss how they manage the prior authorization process for antiobesity agents to improve the quality of their care delivery, including:The information to collect during patient visitsThe available resources to help you submit prior authorizationsThe supporting documents that are often necessary to accompany prior authorizationsHow to address denials and appealsWhen to access manufacturer-based or foundation-based financial assistancePresentersJoseph Kim, MD, MPH, MBAPresidentQ Synthesis, LLCNewtown, PennsylvaniaManish Shah, MDClinical Associate Faculty MS1 PreceptorUniversity of Florida College of MedicineGainesville, FloridaMartha Grugel, MAMedical AssistantWesley Chapel, FloridaLink to full program: https://bit.ly/45P0v8z
Food manufacturers cave to RFK Jr. agenda to eliminate artificial dyes; Diet, exercise ameliorate tinnitus symptoms in overweight seniors; Long work hours may foster deleterious brain changes; Blood in urine—why is it such a big deal? Suggestions for a dog with panic attacks ahead of weather fronts; Diets high in fruits and vegetables counter disordered sleep.
In this conversation, Dr. Stephan J. Guyenet joins Dr. Buck Joffrey to discuss the complex mechanisms of body fat regulation, focusing on the role of the lipostat and leptin. He explains how the body regulates fatness through hormonal signals and the implications of leptin resistance in obesity. The discussion also covers practical strategies for weight management, the impact of stress and sleep on leptin levels, and critiques of the carbohydrate insulin model of obesity. Learn more about Dr. Stephan J. Guyenet: https://www.stephanguyenet.com/ - Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://ru01tne2.pages.infusionsoft.net/?affiliate=0 Book a FREE longevity coaching consultation with Dr. Buck Joffrey: https://coaching.longevityroadmap.com/
Anthony is an award winning film producer, multifaceted entrepreneur, author and is seen as a visionary in shaping the future of both wellness and entertainment. His personal transformation—from “fat Lolli” to “six-pack Lolli”—inspired millions, and his journey is the centrepiece of his acclaimed documentary From Fat Lolli to 6 Pack Lolli. This 7 time nominated, 4 time award winning viral documentary gained Anthony over 1.4 million followers on Instagram But Anthony's influence extends beyond personal transformation. As the founder of Lolli Brands Entertainment, he produces ground-breaking films like The Guru, which highlights innovative health and wellness topics. His latest project, the highly anticipated five-part documentary Biohack Yourself, places him at the forefront of the longevity and wellness movement. The documentary has featured some of the podcast favourites past guests such as Dr Amen, Dr Steven Gundry and Ben Greenfield, to name a few. Here are some of the things we talked about in today's podcast. Takeaways · Anthony's journey began with a realisation of the impact of obesity on his family. · He treated his weight loss like a business, hiring professionals for support. · The importance of a strong 'why' can drive significant change. · Transformation is about more than just losing weight; it's about identity. · Building a supportive community can enhance motivation and accountability. · Understanding body composition is key to maintaining weight loss. · There are societal prejudices within the weight loss community that need addressing. Transparency in sharing personal struggles resonates with audiences. · Loose skin is a common concern for those losing weight. · Identity plays a crucial role in maintaining weight loss. · Biohacking can enhance mental clarity and decision-making. · Awareness of environmental toxins is essential for health. · Grounding and red light therapy are effective biohacks. · Education and knowledge are key to making informed health choices. · Community support is vital for long-term weight maintenance. · The journey of transformation is ongoing and requires continuous effort. Today's podcast is sponsored by my Keane Edge Group Coaching Program: https://briankeanefitness.com/the-keane-edge-program (Website) Lolli Brands Entertainment | documentary production (Instagram) https:// www.instagram.com/anthonylolli/ (Youtube) Anthony Lolli - YouTube (Twitter) https://twitter.com/Anthony_Lolli
Social media is flooded with advertisements for popular obesity medications. But how do consumers avoid being scammed into purchasing knockoff versions that may not be effective or even safe? Recently, the U.S. Food and Drug Administration decided to prohibit mass compounding of some weight loss medications, but it could confuse people more than ever about their options. Dr. Andrew Wong of Hartford HealthCare Medical Group Primary Care gave us clarity on this. Image Credit; Getty Images
Screen for ADHD in patients with obesity, particularly if treatment response is poor or disordered eating behaviours Assess family members when ADHD is diagnosed, as it often runs in families Recognise that stimulants may unmask undiagnosed ADHD, offer short-term benefits while awaiting specialist care ADHD diagnosis can greatly improve functioning, eating habits, and self-awareness Reframe ADHD and obesity as neurobiological conditions, not failures of willpower, to reduce stigma and support patient engagement Host: Dr David Lim | Total Time: 33 mins Experts: Dr Catherine Bacus, Bariatric General Practitioner Register for our fortnightly FREE WEBCASTSEvery second Tuesday | 7:00pm-9:00pm AEST Click here to register for the next oneSee omnystudio.com/listener for privacy information.
Episode 2660: Vinnie Tortorich and Chris Shaffer talk to callers about how consistency makes a difference even when life gets overwhelming, and more. https://vinnietortorich.com/2025/06/consistency-makes-a-difference-episode-2660 PLEASE SUPPORT OUR SPONSORS YOU CAN WATCH ALL THE PODCAST EPISODES ON YOUTUBE - Consistency Makes a Difference No one wakes up wanting to be fat. Fat-shaming is not acceptable; however, there are indicators in society that demonstrate the health of the country is declining. (5:00) Obesity is less about genetics than we tend to think. Even the Pixar movie WALL-E sends a nod to this trend. The Callers Dave has a question about rowing on the Concept 2; he gives a bit of backstory on how he discovered Vinnie and Anna Vocino. (17:45) He had weight loss with NSNG, but life happened over the years, and he fell into bad habits. (22:00) He was then diagnosed with cancer and dialed back into NSNG®. He's trying to dial in his Concept 2 routine. There is no such thing as permanent weight loss. Weight loss only works when you are eating right. (26:00) It only works as long as you are willing to work it! Vinnie gives Dave suggestions about using the Concept 2 and getting into Zone 2 and other challenges. (27:00) Charles is next: (39:30) He has been going through a slow process after knee replacement surgery; Vinnie gives some suggestions and encouragement. He lost approximately 40 pounds before the surgery and feels ahead of the game, despite healing being a slower process. Nina chats about how she went off plan and how she is struggling to get back to where she was. (50:00) Life will ALWAYS get in the way, so you cannot let that derail you. Nina has a summer reading list of books from Vinnie's Amazon Book Club: , , and Josh's daughter has health issues that require a lot of hospital stays. (58:00) His schedule challenges his ability to be consistently active. (1:05:00) Josh's approach and level of gratitude despite his challenges are inspiring. (1:11:00) Consistency will always make a difference in how you eat and exercise. More News If you are interested in the NSNG® VIP group, it's closed for registration, but you can get on the wait list - Don't forget to check out Serena Scott Thomas on Days of Our Lives on the Peacock channel. “Dirty Keto” is available on Amazon! You can purchase or rent it . Make sure you watch, rate, and review it! Eat Happy Italian, Anna's next cookbook, is available! You can go to You can order it from . Anna's recipes are in her cookbooks, website, and Substack–they will spice up your day! Don't forget you can invest in Anna's Eat Happy Kitchen through StartEngine. Details are at Eat Happy Kitchen. There's a new NSNG® Foods promo code you can use! The promo code ONLY works on the NSNG® Foods website, NOT on Amazon. https://nsngfoods.com/ PURCHASE DIRTY KETO (2024) The documentary launched in August 2024! Order it TODAY! This is Vinnie's fourth documentary in just over five years. Visit my new Documentaries HQ to find my films everywhere: Then, please share my fact-based, health-focused documentary series with your friends and family. Additionally, the more views, the better it ranks, so please watch it again with a new friend! REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! PURCHASE BEYOND IMPOSSIBLE (2022) Visit my new Documentaries HQ to find my films everywhere: REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! FAT: A DOCUMENTARY 2 (2021) Visit my new Documentaries HQ to find my films everywhere: FAT: A DOCUMENTARY (2019) Visit my new Documentaries HQ to find my films everywhere:
Interest and grave concern have been mounting over the impact of agriculture and the food choices we all make on the environment, particularly on climate change. With natural weather disasters occurring much more frequently and serious threats from warming of the atmosphere in general, it's natural to look for places to make change. One person who has thought a lot about this is our guest today, Dr. William Dietz of George Washington University. He's been a prominent voice in this space. Bill, you're one of the people in the field I respect most because our relationship goes back many years. Bill is professor and director of research and policy at the Global Food Institute at George Washington University. But especially pertinent to our discussion today is that Dr. Dietz was co-chair of the Lancet Commission on the global syndemic of obesity, under nutrition and climate change. Today, we'll focus on part of that discussion on beef in particular. Interview Summary Bill, let's start out with a basic question. What in the heck is a syndemic? A syndemic is a word that reflects the interaction of these three pandemics that we're facing. And those are obesity, under nutrition, and we've also called climate change a syndemic insofar as it affects human health. These three pandemics interact at both the biologic and social levels and have a synergistic adverse impact on each other. And they're driven by large scale social forces, which foster clustering and have a disparate impact on marginalized populations. Both in the developed and equally important, in the developing world. Here are a couple of examples of syndemics. So, increased greenhouse gases from high income countries reduce crop yields in the micronutrient content of crops, which in turn contribute to food insecurity and undernutrition in low and middle income countries. And eventually the reduction in crop yields and the micronutrient content of crops is going to affect high income countries. Beef production is a really important driver of the climate change, and we're a major contributor in terms of the US' contribution. And beef production drives both methane and nitrous oxide emissions, and in turn, the consumption of red and processed meat causes obesity, diabetes, colon cancer, and cardiovascular disease. And finally, obesity, stunting and nutrition insecurity occur in the same children and in the same population in low- and middle-income countries. Okay, so we'll come back to beef in a moment, but first, help us understand the importance of agriculture overall and our food choices in changing climate. Well, so I think we have to go back to where this, the increase in mean global surface temperatures began, in about 1950. Those temperatures have climbed in a linear fashion since then. And we're now approaching a key level of increase of 1.5 degrees centigrade. The increase in mean surface temperature is driven by increased greenhouse gases, and the US is particularly culpable in this respect. We're it's second only to China in terms of our greenhouse gas emissions. And on a per capita basis, we're in the top four with China, India, and Brazil and now the US. And in the US, agriculture contributes about 10% of greenhouse gas emissions, and about 30% of fossil fuels are responsible for greenhouse gas emissions. But when you look at the actual contribution of car use among the fossil fuel use, it's pretty close to the contribution of greenhouse gases from agriculture. The important point here is each one degree increase centigrade in air temperatures associated with a 7% increase in water vapor. And this is responsible for the major adverse weather events that we're seeing today in terms of increased frequency and severity of hurricanes, the droughts. And I learned a new term from the New York Times a couple of days ago from the science section, which is atmospheric thirst. I had trouble understanding how climate change would contribute to drought, but that same effect in terms of absorbing moisture that occurs and drives the adverse weather events also dries out the land. So increasingly there's increased need for water use, which is driven by atmospheric thirst. But that increase in air temperature and the increase in water vapor, is what really drives these storms. Because in the Pacific and in the Atlantic and the Gulf of Mexico, this increase in air temperature is associated with an increase in water temperature, which further drives the increase in the severity of these storms. Thanks for that background. Now let's get to beef. You and I were not long ago at the Healthy Eating Research conference. And you gave what I thought was a very compelling talk on beef. We'll talk in a minute about how much beef figures into this overall picture, but first, tell us how beef production affects both climate and health. And you mentioned nitrous oxide and methane, but how does this all work? Cattle production is a big driver of the release of methane. And methane comes from cow burps. The important thing to understand about methane is that it's 80 times more powerful than CO2 in terms of its greenhouse gas emission. And that's because it has a very long half-life when it gets up into the atmosphere? Well, actually it's interesting because the half-life of methane is shorter than the half-life of nitrous oxide. So, it's an appropriate target for reduction. And the reduction has to occur by virtue of reduced beef consumption, which would reduce beef production. The other piece of this is that nitrous oxide is derived from fertilizer that's not absorbed by plants. And the application of fertilizer is a very wasteful process and a huge percent of fertilizer that's applied to crops is not absorbed by those plants. And it washes into the Mississippi River and down to the Gulf of Mexico. But also, increases the genesis of nitrous oxide. And nitrous oxide is an even more powerful greenhouse gas than methane. About 260 times more powerful than CO2 with a very, very long half-life. So, as a target, we really ought to be focused on methane, and if we're going to focus on methane, we need to focus on beef. You could imagine people who are opposed to these views on climate change making fun of cows burping. I mean, are there enough cows, burping enough where the methane that's coming out is a problem? Yes. Maybe a better term that we can use is enteric fermentation, which is in effect cow burps. But enteric fermentation is the major source of methane. And nitrous oxide, the same thing. The agricultural system which supports cattle production, like the feedlot fattening from corn and wheat. The genesis of nitrous oxide is a product of fertilizer use and fertilizer use is a real important source of nitrous oxide because of the amount of fertilizer which is not absorbed by plants. But which washes into the Mississippi River and causes the dead zone in the Gulf, but also generates an enormous amount of nitrous oxide. So, between those two, the enteric fermentation and the origin of nitrous oxide from fertilizer use, are a lethal combination in terms of increasing greenhouse gas emissions. And it's important to know that those greenhouse gas emissions are associated with important declines in crop yields. Crop yields have declined by about 5% for maize for wheat, for soybeans, and somewhat less for rice. These crop yields have yet to affect the US but are clearly a problem in the Global South. In your talk, you cited a paper by Scarborough and colleagues that was published in the Journal Nature Food that modeled the environmental impact of various diets. Could you please explain what they found? This was a really nice study of four diets in the United Kingdom. Actually it was five diets. They looked at vegans, vegetarians, low meat eaters, medium meat eaters and high meat eaters. And looked at the contribution of these diets to the genesis of methane, nitrous oxide, and also importantly, land use and water use. And the most expensive, and the most detrimental environmental impact of these diets, were the among the high meat eaters. These were substantially greater than than the genesis of for example, methane by vegans. For example, high meat eaters generated about 65 kilograms per day of methane compared to vegans, which generated only four kilograms per day of methane. And when you reduce beef, and there were two lower categories, these measures come much more into line with what we'd like to have. The low meat eaters generate about half of methane that the high meat eaters generate. This is also true for their genesis of nitrous oxide. And importantly, the land use among vegans and vegetarians is about a third of the land use required for the production of beef. And water use by meat production is about twice that generated by the water use by the production of plant-based diets. I think these are important data because they, they really reflect the importance of a lower meat consumption and higher plant-based diet. Not just in terms of greenhouse gases, but also in terms of land use and water use. Not to mention health. Not to mention health. Yes. I think it's important to continue to remind ourselves that beef consumption is associated with a variety of chronic diseases like obesity, like diabetes, like colon cancer and like cardiovascular disease. So, there's this double whammy from beef consumption, not only on the climate but also on human health. In your talk that I heard it was interesting to see how you interpreted this information because you weren't arguing for no beef consumption. Because you were saying there could be tremendous benefit from people going from the high beef consumption category to a lower category. If you could take all the people who are consuming beef and drop them down a category, it sounds like there would be tremendous benefits. People could still have their beef but just not have it as often. Right. I think that's an important observation that we're not talking about the elimination of beef. We're talking about the reduction in beef. And the Eat Lancet Commission pointed out that protein consumption in the US was six times what it should be in terms of human needs. And a lot of that protein comes from beef. And there's this belief, widespread, popular belief that beef is the most important source of protein. But comparisons of plant-based diets and plant-based proteins have an equivalent impact and equivalent absorption pattern like beef and are equally nourishing. That's a really important thing to make prominent because people are thinking more and more about protein and it's nice to know there are various healthier ways to get protein than from a traditional meat diet. Well, one of the, one of the important reports from the dietary guidelines advisory committee was to reclassify lentils, beans and peas as proteins rather than vegetables. And I think that's a, something which has not been widely appreciated, but it gives us a real important area to point to as an alternative protein to beef. Bill, on this calculus, how important is the way the cattle are raised? So, you know, you have big cattle farms that might have a hundred thousand cattle in a single place being raised in very close quarters. And it's industrial agriculture, the kind of the epitome of industrial agriculture. But more and more people are beginning to study or experiment with or actually implement regenerative agriculture methods. How much would that help the environment? That's kind of a complicated question. If we just start with beef production, we know that grass fed beef has a healthier fatty acid profile than feedlot fat and beef. But the total generation of greenhouse gases among grass fed beef is greater because they're fostered on land for a longer period of time than those cattle which are committed to feedlots. My understanding is that most of the cattle that go to feedlots are first raised on grass and then moved to feedlots where they're fed these commodity products of corn and wheat and, and maybe not soy. But that feedlot fattening is a critical step in beef production and is associated with overcrowding, antibiotic use, the generation of toxic dust really. An enormous amount of fecal material that needs to be adequately disposed of. It's the feedlot fattening of beef is what adds the adverse fatty acid content, and also contributes to the local environment and the damage to the local environment as a consequence of the cattle that are being raised. Appreciate you weighing in on that. Let's talk about what might be done. So how do we go about increasing awareness, and the action, for that matter, in response to the contributions of beef production to climate change? It begins with understanding about the contribution of beef production to climate change. This is not a well understood problem. For example, there was a study of 10 major news sources a couple of years ago which asked what the major contributions were of climate change. And they surveyed a hundred articles in each of 10 sources of information, which were popular press like New York Times, Washington Post, etc. And, at the top of that list, they characterize climate change as a consequence of fossil fuels. Whereas a recognition of the contribution of the agricultural system was at the bottom of that list and poorly covered. It's no surprise that people don't understand this and that's where we have to start. We have to improve people's perception of the contribution of beef. The other thing is that I don't think we can expect any kind of progress at the federal level. But in order to build the critical mass, a critical focus, we need to look at what we can personally change. First in our own behavior and then engaging family, peers and organizational networks to build the political will to begin to generate federal response. Now, this brings up a really critical point that I'm not sure we have the time to do this. I don't think we are facing the whole issue of climate change with the kind of emphasis and concern that it deserves. I mentioned at the outset that the mean surface temperature is increasing rapidly. And the expectation was, and the goal was to achieve no greater than a 1.5 degrees centigrade increase by 2050. Well, in 2024, there was already a report that the mean surface temperature had already increased in some places by 1.5 degrees centigrade. So there has to be an urgency to this that I don't think people, are aware of. Youth understand this and youth feel betrayed and hopeless. And I think one of the important characteristics of what we can personally change, in engaging our family and peers, is a way of beginning to generate hope that change can occur. Because we can see it if it's our family and if it's our peers. Another important and critical strategy at the institution and state level is procurement policies. These, I think, are the most powerful tool that we have to change production at the municipal or local level, or at the state level. And we were part of an effort to get the HHS to change their procurement policy for their agencies. And although at the very last minute in the Biden administration, they agreed to do this, that's been superseded now by the changes that Trump has instituted. Nonetheless, this can be a local issue and that's where local change has to occur if we're going to build political will from the ground up. Bill, tell me a little bit more about procurement because a lot of people don't even think about that term. But it turns out that the federal government and local and state governments buy lots of food. How is it that they buy lots of food and how they could have sway over the food environment just by their purchasing decisions? So, let's take schools. Schools are a logical place. They have large contracts with vendors and if they set standards for what those vendors were supplying, like insisted on alternative proteins in at least some of their meal services that would have a big impact on reducing greenhouse gas emissions from school meals. And would have a positive impact on the health of students in those schools. This is known as value-based purchasing. Purchasing of products related to values that have to do with not only greenhouse gases, but also animal husbandry and fair workers' rights, and strategies like that. These are possible. They should be beginning in our universities. And this is an effort that we have underway here at George Washington University. But there are even better examples where universities have used plants as a default option in their cafeterias, which has, shown that when you do that and when you make the plant-based option the only visible choice, people choose it. And, in three universities, Lehigh, Rensselaer at Polytech, and Tulane, when they made plant-based options the only visible option, although you could ask for the alternative, the choices went up to 50 to almost 60 to 80% when the plant-based option was offered. And these were things like a lentil olive and mushroom spaghetti, which has a very low greenhouse gas emission. In fact, the net effect of these choices was a 24% reduction in greenhouse gases on days when the default was offered. These are practical types of initiatives. We need to increase the demand for these options as an alternative to beef. Bill, I like how you're approaching this from kind of the big top level down, but also from the ground up. Because you talk about things that the federal government could do, for example, but also how important individual choices are. And how people can work with their families and friends and have an inspirational effect by changing their own behavior. Those sorts of things make me hopeful. But let me ask, how hopeful are you? Because I'm hearing from you this sort of dire picture that we might be too late, and that the climate change is happening so rapidly and that the social change needed to overcome that is painfully slow. But on the other hand, you're speaking some optimistic things. So how do you feel overall about where this is going? I'm moderately hopeful. And moderately hopeful because I think young people are engaged. And we need to address the hopelessness that many of them feel. They feel betrayed by us. They feel like the adults in this country have let them down and have not focused enough. That's understandable. Particularly now given the distractions of the new administration. And I think we're in a real crisis and things all of a sudden are very fluid in terms of national initiatives. They've been dominated by the Trump administration, but I think that's changing. And I think that the kind of despotism that led to the station of troops in California, in Los Angeles, is a case in point of overreach of the government. The kind of ICE activities really deserve resistance. And all of that, I think, plays into this notion that we're in a fluid time. This is not a time that people are necessarily going to focus on beef consumption. But the fact that all of these climate changes, clearly a major issue at least for those who admit it, means that we need to begin and continue to build the political will for changes in beef consumption as well as changes in transportation policy. I think that actually beef consumption is an easier target then changes in transportation policy, which is driven by the way our communities are constructed. And in many cases, the only way to get from one place to another is by car, which means that we're going to have a continued dependence on fossil fuels. I don't think we can say the same thing about beef consumption because if we institute reductions in beef consumption, I think we can have a very immediate and longer-term impact on greenhouse gas emissions and therefore on climate change. Bio William (Bill) Dietz is the Director of Research and Policy for the Global Food Institute and a Professor in the Department of Exercise and Nutritional Sciences. Dietz is a member of the National Academy of Medicine (formerly the Institute of Medicine) and serves as a consultant to the Roundtable on Obesity Solutions. He also is the Director of the STOP Obesity Alliance at The George Washington University. He served as Director of the The Sumner M. Redstone Global Center for Prevention & Wellness until June 30, 2024. He is Co-Chair of the Washington, DC Department of Health's Diabesity Committee, a Commissioner on the Washington, DC Office of the State Superintendent of Education's Healthy Youth & Schools Commission, and Chair of its Subcommittee on Physical Activity. Dietz is also Co-Chair of The Lancet Commission on Obesity.
What happens when a doctor realizes that pills weren't healing her patients—but plants were? You have the makings of a wonderful interview with triple board-certified physician Dr. Regina Ragasa.As a specialist in obesity and lifestyle medicine, Regina opens up about her transformation from a conventional doctor (aka - “drug dealer”) to a fierce advocate for whole food, plant-based nutrition.You'll hear how a single conversation with a colleague sparked her interest in reversing chronic illness through diet—ultimately leading to a life-changing shift in how she practices medicine.Dr. Ragasa breaks down her three core rules for sustainable weight loss and optimal health:Remove all animal productsEliminate ultra-processed foodsCook without oilEach rule is backed by science and real-life success stories—including the inspiring case of her “patient zero” who reversed diabetes without medication.Rip and Dr. Regasa dive deep into the challenges and misconceptions surrounding obesity, GLP-1 medications, and food culture and, with honesty and hope, she urges us all to embrace food as medicine and rethink the way we define health and healing.Episode WebpageWatch the Episode on YouTubeSPECIAL Food Promo for Podcast Listeners Only!Use code: podcast10 to receive 10% off food orders at plantstrong.com Upcoming Events:Join us for our 2025 Plantstrong Retreat in Black Mountain, NC - Nov 9-14, 2025: https://plantstrong.com/pages/black-mountain-retreat Let Us Help Your PLANTSTRONG JourneyUse Code: KALE20 for $20 off Annual Subscription at https://home.mealplanner.plantstrong.com/ COMPLEMENT: Use code PLANTSTRONG for 30% off at https://lovecomplement.com/pages/plantstrong-special-offer Leave Us a Voicemail QuestionLeave us a voicemail: https://www.speakpipe.com/plantstrong Follow PLANTSTRONG and Rip Esselstynhttps://plantstrongfoods.com/ https://www.facebook.com/GoPlantstrong https://www.instagram.com/goplantstrong/https://www.instagram.com/ripesselstyn/ Follow the PLANTSTRONG Podcast and Give the Show a 5-star RatingApple PodcastsSpotify
Obesity is far more complex than willpower. In this episode, we spoke with Robert F. Kushner, MD, renowned weight management expert, to explore how the medical community’s understanding of obesity has shifted – from a perceived lifestyle choice to a recognized chronic condition shaped by biology, genetics, and environment. Our guest expert breaks down modern diagnostic tools, new treatments like GLP-1 receptor agonists, and how to create stigma-free care. We also spoke to patient guest, Michele Tedder, RN, host of Dear Healthcare Provider, who shares her lifelong struggle with weight and related health issues, how GLP-1 medication helped her, and how obesity should be treated with the same compassion and seriousness as other chronic diseases. See omnystudio.com/listener for privacy information.
Send us a textWelcome back Rounds Table Listeners! Today we have another special episode— Trial Files turns two years old this June, and we're celebrating with an episode summarizing the Top 5 RCTs in the Trial Files catalogue to date. Dr. Mike Fralick takes us through five trials in 15 minutes. Here we go!1. Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes (0:00 - 3:08)2. Restrictive or Liberal Transfusion Strategy in Myocardial Infarction and Anemia (3:09 - 5:37)3. Once-Weekly Semaglutide in Persons with Obesity and Knee Osteoarthritis (5:38 - 8:33)4. Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections (8:34 - 11:22)5. Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction (11:23 - 13:23)Happy 2nd Birthday, Trial Files!A free monthly newsletter on practice-changing trials, delivered straight to your inbox-- sign up at https://trialfiles.substack.com/ (13:24 - 14:19)Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods
Maximizing Fitness, Fat Loss & Running Through Perimenopause
Ever feel like you're trying to learn everything you can about best health, nutrition, and fitness methods to feel, look, and perform your best but you're still not seeing great results? In this refreshingly honest episode, Louise, one of the world's leading health, fitness, and performance experts, unpacks the idea of mental obesity, which is consuming too much information without taking meaningful action. If you're an active, health-conscious woman trying hard to navigate perimenopause advice, this episode will speak right to you!Louise shares real-life stories from women overwhelmed by podcasts, leading expert advice, books, social media influencers, and conflicting methods. She reveals how this mental overload keeps us stuck, stressed, and second-guessing our every move. Through her award-winning Academy education and methods, Louise shares how trimming the mental fat leads to more energy, badass hormone balance, a leaner physique, peak performance, and refreshing peace of mind.If you're constantly researching and trying all the things, but still not feeling better, it's time to rethink your approach. This week, join us in selecting fewer expert opinions, trusting the process, and giving your body (and brain) a break.Link to check out our free nutrition guide and join other fierce active ladies taking charge of their holistic health and fitness in our award-winning Badass Breakthrough Academy to thrive through perimenopause with less stress: https://www.breakingthroughwellness.com/ Take advantage of our podcast listener discount and save 20% off all of Kion's science-backed clean products: https://www.getkion.com/pages/maximizing Link to our FullScript where you can see our curated best supplement picks & save 20%: https://us.fullscript.com/welcome/breakingthroughwellness/store-startEpisode Highlights:(0:00) Intro(2:57) What is mental obesity?(3:43) The perimenopause information overload(6:11) The smart woman's struggle to start(7:25) Too many experts, too little clarity(9:07) The power of shared community support(10:49) Real progress through real-life tweaks(12:49) Why one-size diets no longer work(15:45) You don't need more voices(19:04) The problem with not giving things a chance(20:13) Are you taking action, or just learning?(24:38) Knowing your unique physiological stress point(28:08) Choose fewer experts, trust the right ones(32:24) Final reflection: Trim the fat, trust yourself(40:45) OutroTune in weekly to "Maximizing Fitness, Physique, and Running Through Perimenopause" for a simple female-specific science-based revolution. Let's unlock our best with less stress!I'd love to connect!Instagram
⚠️ Warning: Listening to this episode may cause spontaneous inspiration, side effects include rethinking innovation, falling in love with Denmark, and Googling “intelligent bricks.” Meet Anne C. Fleischer — engineer, innovator, former LEO Pharma exec, and now leading Consumer Engagement & New Business Models for Obesity at Novo Nordisk. She grew up in a village so small that your soccer team was whoever showed up to class that day. She wanted to be a helicopter pilot or a doctor, but got motion sickness and couldn't get into med school...... So she built a new path- literally - constructing heart pump mannequins, NFC-enabled pavement tiles, and eventually digital health products that helped millions.
Today we do a round-up of some of the recent semaglutide trials. Does semaglutide ever miss? But what about tirzepatide, which causes even more weight loss?We also review two new critical care trials, FLUID and the UK-ROX, new platelet transfusion guidelines, and a new retrospective study of apixaban vs rivaroxaban vs warfarin. Oral Semaglutide for Diabetes with Cardiovascular Disease or CKD (SOUL)Semaglutide for Peripheral Artery Disease (STRIDE)Semaglutide for MASH (ESSENCE)Semaglutide vs Tirzepatide for Obesity (SURMOUNT-5)Normal Saline vs Lactated Ringers (FLUID)Conservative Oxygen Targets in Mechanically Ventilated Patients (UK-ROX)Platelet Transfusion GuidelinesApixaban vs Rivaroxaban vs Warfarin Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R
Legendary powerlifter and IFBB Pro bodybuilder Stan Efferding is also one of the most thoughtful practitioners of evidence based nutrition and training. Stan joins for a pure masterclass in:-Why we have an obesity and metabolic health crisis -How much of the benefit of healthy lifestyle is directly attributable to fat loss-Why the classic “eat less/move more” advice is truthful but not helpful -What is Stan's Vertical Diet and how has it helped his clients become healthier-Why diets fail?-The role of food environments -Sorting the facts from the fiction about Blue Zones-The power of walking after meals-Notes on better sleep-LDL cholesterol risks-And a ton more wisdom that will help you01:30 The Obesity and Metabolic Health Crisis04:47 The Role of Ultra-Processed Foods05:18 The Impact of Appetite Hormones22:34 The Vertical Diet: A Comprehensive Approach30:23 Understanding FODMAPs and Dietary Sensitivities35:17 Debunking Diet Myths and Misconceptions46:45 Questioning Longevity Studies47:41 Healthy User Bias in Meat Consumption48:28 Processed Meat and Cancer Risk50:39 Alcohol and Health Myths51:47 Mediterranean Diet and Lifestyle53:11 Vertical Diet: Bulking vs. Cutting58:33 Appetite Regulation and Food Swaps01:08:20 Meal Prep and Dietary Adherence01:17:08 Exercise and Sustainable FitnessI've been putting a lot of time and effort into making these new episodes valuable for you. You can help me get these great guests and their knowledge in front of more people by:-Subscribing and checking out more episodes-Sharing on your social media (please tag me - I promise I'll respond)-Sharing with the friend you think of who needs this episodeFollow Andrew Coates:Instagram:@andrewcoatesfitnessJoin My Email List:www.andrewcoatesfitness.comGet the RP App at www.rpstrength.com/coates - use the code COATESRPUse Code ANDREWCOATESFITNESS to save 10% off at https://justbitememeals.com/Use MacrosFirst for tracking nutrition https://www.macrosfirst.com/Go to www.knkg.com/Andrew59676 for 15% off your KNKG bag.Join my Forever Strength 13 week women's online strength program www.foreverstrength.ca and use the code: liftfree to save 10%Get 13 weeks of progressive full body strength workouts. Choose between 2 to 4 workouts each week, workout at your schedule. And have me to coach and support when you need it. You also get access to my Facebook community, full of other supportive members. Join today to secure your spot, they're limited to 125 total. Starts Monday June 30th
Summary:In this episode of Trainer's Bullpen, host Chris Butler speaks with Dr. Geoffrey Desmoulin about the critical research on prone restraint techniques in law enforcement.They discuss the conflicting views on the safety of these techniques, the physiological risks involved, and the implications of the Bronstein case, which serves as a cautionary tale for law enforcement practices. The conversation emphasizes the importance of understanding the biomechanics and physiology behind restraint techniques, particularly the role of CO2 buildup in medicalrisks. In this conversation, Dr. Desmoulin discusses eight critical risk factors for sudden death in prone restraint cases. The discussion also highlights the importance of understanding the physiological responses duringrestraint and offers strategies for law enforcement to mitigate risks associated with respiratory compromise.Takeaways:• Physiological effects of prone restraint can lead to serious medical risks.• The recent Bronstein case highlights the dangers of prolonged prone restraint.• Communication of medical risks is crucial for law enforcement training.• The urgency of repositioning subjects in restraint is critical.• Biomechanics play a significant role in understanding restraint techniques.• Training should incorporate findings from recent research on restraint risks. Obesity increases pressure on lungs and reduces tidal volume.• Drugs like meth and opioids disrupt carbon dioxide regulation.• Anxiety can lead to hyperventilation and increased airway resistance.• Downward force during restraint can compress thoracic vessels.• Time is a critical factor in managing respiratory risks.• Reducing the duration of struggles can minimize health risks.• Research should focus on dynamic immobilization scenarios.Listeners should check out the online courses available at GTD Scientific https://gtdscientific.com/
If you've been feeling off in your 30s, 40s, or 50s—tired, bloated, gaining weight despite healthy habits—you're not imagining it. These are common signs that your metabolism, hormones, and overall biochemistry are shifting. But here's the problem: most advice still treats women like we're all the same.In this episode of Sofia Unfiltered, we talk with Dr. Onikepe “Onyx” Adegbola, a physician-scientist and expert in lifestyle, menopause, and obesity medicine. She's also the founder of Casa de Sante, a health tech company using AI and personalized diagnostics to transform how adults approach their health.Together, we explore:What's actually changing in your body during midlifeWhy generic weight loss or “just eat less” advice failsHow AI and advanced testing are reshaping personalized careSimple, science-backed changes you can start todayIf you're ready to stop guessing and start getting real answers about your health, hormones, and energy, this is your starting point.
If you're stuck in a cycle of food restriction and calorie counting but can't seem to shift the weight and keep it off, you could be doing it all wrong!In this eye-opening episode, I sit down with Yalda Alaoui, a certified health coach and founder of Eat Burn Sleep, to debunk the common misconception that calorie counting is the key to weight loss. Featured in Forbes, Vogue, and The Times, Yalda shares her personal journey of battling two autoimmune conditions and how it led to her revolutionary approach to wellness. We discuss the flawed nature of calorie counting, the importance of gut health, and sustainable alternatives that can improve both mental and physical well-being. This episode is a must-watch for anyone who has ever struggled with guilt over food choices or felt trapped by obsessive dieting. Learn how true health involves more than just numbers on a scale, and why emotional and mental well-being are crucial elements of a balanced lifestyle.While you watch this episode, it's important to remind yourself that you are more than your weight and our bodies are just a vessel to help us enjoy life to its full potential
Have you ever felt addicted to ultra-processed foods---like you knew they were bad for you, but you couldn't stop indulging? This happened to our guest today who at age 15 weighed over 300 lbs. And she didn't know who she was anymore. Today, Penelope Popken is 19 and she's overcome her addictive behavior. During this revealing interview, mother and daughter discuss what led to Penelope's struggles with weight, the drugs she took, the (mostly unhelpful) therapists' recommendations and more. They go over how most weight loss drugs (including Ozempic) and other quick fixes (like gastric bypass surgeries) have dire consequences. And they cover what it took to turn things around for Penelope. By the way, her healing path included not just returning to real nourishing food but addressing dysfunctional family patterns that contributed to unhealthy behavior. Since both Helene and Penelope have had to overcome their individual struggles with unhealthy eating and obesity, they have started the Step it UP program to help other women in just their position. After failed attempts at diets, injections, and pills, they are on a mission to help everyone learn how to nourish themselves more deeply and to thrive. Visit Helene and Penelope's websites: Step it UP and Step It UP Accountability Group Register for the Wise Traditions conference at wisetraditions.org Check out our sponsors: Optimal Carnivore and Alive Waters
Why don't medical schools teach doctors about nutrition? New study adds to evidence that glyphosate can cause cancer; Former FDA chief calls for low-carb dietary guidelines; 2024 analysis shows saturated fat and cholesterol restriction ineffective for heart disease prevention; Natural support for the pain of vertebral compression fractures; Are “fruit and veggie” pills really as effective as they claim? Facial and neck massage facilitate brain's natural waste disposal, offering hope for neurodegenerative disorders.
The tragic death of a second non-ambulatory DMD patient treated with Sarepta's Elevidys gene therapy marks a turning point for the field and should drive all stakeholders to come together to figure out how to safely treat patients with this new modality. On the latest BioCentury This Week podcast, BioCentury's analysts discuss the opportunity FDA, companies and patient advocates have to share data and identify a safe path forward for the gene therapy field, both in DMD and beyond.The analysts also review promising early data for amylin agonists to treat obesity from Metsera and Eli Lilly, and discuss the vision for FDA's future laid out by Commissioner Marty Makary and CBER director Vinay Prasad. This episode of BioCentury This Week was sponsored by ICON Biotech.View full story: https://www.biocentury.com/article/656214#biotech #biopharma #pharma #lifescience #obesity #FDA #DMD00:01 - Sponsor Message: ICON Biotech01:19 - Gene Therapy Safety11:55 - Amylin in Obesity18:17 - FDA's FutureTo submit a question to BioCentury's editors, email the BioCentury This Week team at podcasts@biocentury.com.Reach us by sending a text
Did you know that one 20-ounce soda can pack more sugar than five donuts—and still leave you hungry? In this episode, I unpacked the deceptively sweet world of sugar-sweetened beverages from sodas and sweet teas to fruit juices and even those “healthy” smoothies. I busted eight common myths that might be sabotaging your wellness journey without you even realizing it. We talked about how liquid calories sneak past your hunger cues, spike blood sugar, fuel cravings, and trigger fat storage. I broke down why fruit juice isn't the same as whole fruit, why diet sodas and energy drinks aren't a free pass, and why even your favorite boba tea might be more dessert than drink. So whether you're sipping flavored coffee or reaching for coconut water, it's time to start reading those labels. My challenge to you? Swap one sugary drink a day for water or an unsweetened alternative, your body will thank you for it. Ready to take control of your cravings, boost your energy, and finally see results on the scale? Tune in now to uncover the hidden truths about sweetened drinks and start making smarter choices that truly support your health goals! Episode Highlights: The hidden impact of sugar-sweetened beverages on weight gain and metabolic health Why liquid calories don't satisfy hunger and often lead to overeating Eight common myths about sweet drinks—busted with science The truth about fruit juice, diet sodas, smoothies, and boba tea How sweet drinks spike blood sugar, insulin, and fat storage Smarter alternatives to hydrate without sabotaging your health Practical tips to reduce sweet drink intake and improve energy, mood, and weight loss Connect with Dr. Alicia Shelly: Website | drshellymd.com Facebook | www.facebook.com/drshellymd Instagram | @drshellymd Linked In | www.linkedin.com/in/drshellymd Twitter | @drshellymd About Dr. Alicia Shelly Dr. Alicia Shelly was raised in Atlanta, GA. She received her Doctorate of Medicine from Case Western Reserve University School of Medicine in Cleveland, OH. Dr. Shelly has been practicing Primary Care and Obesity medicine since 2014. In 2017, she became a Diplomat of the American Board of Obesity Medicine. She is the lead physician at the Wellstar Medical Center Douglasville. She started a weekly podcast & Youtube channel entitled Back on Track: Achieving Healthy Weight loss, where she discusses how to get on track and stay on track with your weight loss journey. She has spoken for numerous local and national organizations, including the Obesity Medicine Association, and the Georgia Chapter of the American Society of Metabolic and Bariatric Surgeons. She has been featured on CNN, Fox 5 News, Bruce St. James Radio show, Upscale magazine, and Shape.com. She was named an honoree of the 2021 Atlanta Business Chronicle's 40 under 40 award. She also is a collaborating author for the, “Made for More: Physician Entrepreneurs who Live Life and Practice Medicine on their own terms''. Resources: FREE! Discover the 5 Reasons Your Weight-Loss Journey Has Gotten Derailed (And How To Get Back On Track!)
Brad Marshall joins David Gornoski to talk about how fattening is about oxygen, why Oxygen is "happier" in CO2, the cellular origin of obesity, subclinical Torpor, how we handle hypoxia, and more. Follow Brad Marshall on X here. Follow David Gornoski on X here. Visit aneighborschoice.com for more
Menopausal hormonal therapy should not be a blanket recommendation for everyone going through menopauseWeight management in women is influenced by hormonal changes throughout life stages.Retrospective analyses can provide insights but have limitations.The wellness industry often oversimplifies complex medical issues.Hormonal replacement therapy may have subtle benefits for weight management.Confounding factors like SSRIs can complicate weight loss efforts.A holistic approach is essential for managing women's health during menopause.Education and awareness are crucial for women navigating menopause.Future research should focus on randomized controlled trials for better clarity.Understanding individual patient experiences is key to effective treatment.Click here to see her studyClick here to follow Dr. Tchang on XClick here to join Dr. Spencer's clinic Vineyard
This week, Bunnie brings on her personal doctor and friend, Dr. Leah Cordovez - a calm, no-BS physician who blends science and nature to actually know her patients. They talk about Dr. C's wild journey from Panama to private practice, what it's like treating Bunnie's weekly “emergencies,” and why the bond between doctor and patient matters more than we think. Dr. C also answers your questions about sleep, endometriosis, weight, poop (yes, really), and how to actually feel better without shame, shortcuts, or guesswork.Dr. Cordovez: Be Well Watch Full Episodes & More:www.dumbblondeunrated.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
A review of the carbohydrate insulin model of obesity and the related proposal that low carbohydrate diets are superior to traditional low fat diets. I begin with a discussion of the theory behind the carbohydrate insulin model, and then assess its plausibility using relevant evidence from rodent studies, dietary studies, ahd controlled feeding experiments. I argue that the scientific evidence does not support the alleged benefits of low carb diets for weight loss in otherwise healthy adults. Recommended pre-listening is Episode 151: Diet and Nutrition, and Episode 152: Obesity, Diabetes, and Hypertension. If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter. https://www.patreon.com/jamesfodor https://www.paypal.me/ScienceofEverything
How One Man Lost Over 300 Pounds Without Any Cardio with Jamie Selzler Lessons learned. (2:02) What episode got him hooked? (3:23) His highest recorded weight. (4:30) Obesity is a disease. (6:21) Food became overpowering. (10:17) The moment he feared for his life. (11:58) Keeping promises to yourself. (16:01) How did the process change his relationship with himself? (19:53) Having the foot on the gas. (21:56) Consistency and discipline TRUMP motivation. (23:26) His #1 message to coaches and trainers. (27:38) The importance of having a team. (30:34) EVERYONE deserves love, respect, compassion, and empathy, NO MATTER their size. (32:48) Celebrate every win and success. (34:04) What would Mom have done? (40:27) Input goals ONLY, not output goals. (42:05) His GLP-1 experience. (48:02) A HUGE opportunity for trainers and coaches. (59:10) The importance of having a support system. (1:01:48) A parting message for those in his shoes. (1:10:46) Related Links/Products Mentioned Visit Legion Athletics for the exclusive offer for Mind Pump listeners! ** Code MINDPUMP for 20% off your first order (new customers) and double rewards points for existing customers. ** June Special: Shredded Summer Bundle or Bikini Bundle 50% off! ** Code JUNE50 at checkout ** Listener Live Podcast with Jamie – Mind Pump # 2574 – Question #4 Aspire Fitness KY DMAIC - The 5 Phases of Lean Six Sigma Mind Pump Podcast – YouTube Mind Pump Free Resources Featured Guest/People Mentioned Jamie Selzler (@jselzler) Instagram Jamie Selzler (@jamselz) TikTok Coach Josh Bowen (@buffgandhi) Instagram Mike Matthews (@muscleforlifefitness) Instagram Dr. William Seeds (@williamseedsmd) Instagram