Podcasts about PCI

Scott Hansen joins Dustin Burleson on The Burleson Box to share his journey from growing a family orthodontic practice to building LeadSigma, a CRM and AI platform transforming how dental and orthodontic practices manage new patient leads. Together, they explore what most practices miss when it comes to follow-up, why “boring” tasks like answering the phone matter more than ever, and how smart automation is unlocking a new era of growth and efficiency.What You'll Learn in This Episode:How Scott tripled his mom's orthodontic practice and sold to Smile DoctorsThe origin story of OrthoChats and how it became Professional Chats Why most CRMs don't work for dental and ortho teams—and how LeadSigma is differentThe key metrics that indicate your practice is leaking new patient leadsHow AI voice agents can answer phones, schedule appointments, and never miss a leadWhy fast follow-up (within seconds, not minutes) boosts conversion rates by over 30%What the best practices are doing to build a Per Se-level patient experienceWhy focusing on “boring but essential” systems is the path to real, scalable growthResources & Mentions:LeadSigma.comUnreasonable Hospitality by Will GuidaraLevel the Curve by Oliver Gelles and Dr. Jamie ReynoldsRuby ReceptionistPer SeShoutouts to Jay Geier, Dan Kennedy, John Carlton, and OrthoFiConnect with Scott Hansen:LeadSigma.com — Learn more and schedule a demoLinkedIn: Scott HansenConnect with Dustin Burleson:BurlesonSeminars.comInstagram: @dustinburlesonseminars Subscribe & Review:If you enjoyed this episode, please leave a review and subscribe to The Burleson Box on Apple Podcasts, Spotify, or wherever you listen. Your support helps us bring powerful conversations like this to more listeners in healthcare leadership. ***The Burleson Box is brought to you by Stax Payments:Save Big on Transaction Fees: Boost Your Bottom Line with Stax Payments.Did you know that your practice can start saving thousands of dollars on your monthly processing costs with our preferred payments partner, Stax? Simplify your practice operations and provide a quality patient experience. Healthcare practices like yours need a way to accept payments simply and securely. That's where Stax comes in.Stax helps you manage your entire payments experience from within one platform. You can safely accept touch-free payments in-person, online, or over the phone, securely store and manage patient information with layered security and Level 1 PCI compliance.
Take advantage of a simpler, more transparent way to process your payments with competitive flat-rate pricing, provided exclusively through Stax. No additional fees or contracts required!Power your practice and get paid faster with simple, safe and secure payment solutions. Have questions? Schedule time to speak with a dedicated payment consultant to learn more.Click Below to Lear More Today:StaxPayments.com/burleson-seminars*** Go Premium: Members get early access, ad-free episodes, hand-edited transcripts, exclusive study guides, special edition books each quarter, powerpoint and keynote presentations and two tickets to Dustin Burleson's Annual Leadership Retreat.http://www.theburlesonbox.com/sign-up Stay Up to Date: Sign up for The Burleson Report, our weekly newsletter that is delivered each Sunday with timeless insight for life and private practice. Sign up here:http://www.theburlesonreport.com Follow Dustin Burleson, DDS, MBA at:http://www.burlesonseminars.com

Giorgia Antonelli"Tutto il mondo è cosa mia"Rossana RossandaElecta Editorewww.electa.itFelicità e libertà, tutti o nessuno, corpo e politica sono le sponde tra cui si muovono queste pagine dedicate a Rossana Rossanda (1924-2020), una ragazza che ha vissuto molte vite in una donna sola: partigiana, critica d'arte, traduttrice, deputata, scrittrice, direttrice editoriale e fondatrice del “Manifesto”. Dalla Resistenza alla crisi del PCI, dalle BR al femminismo, il ritratto di un'esistenza guidata dal dubbio e incapace di tacere davanti alle ingiustizie. Radicale e sempre in corsa.Il volume fa parte della collana OILÀ, curata da Chiara Alessi, che presenta le storie di protagoniste del Novecento. Figure femminili che, nel panorama ‘creativo' italiano e internazionale (dal design alla moda, dall'architettura alla musica, dall'illustrazione alla grafica, dalla fotografia alla letteratura) si sono distinte in rapporto a discipline e mestieri ritenuti da sempre appannaggio dell'universo maschile. I libri, pensati per essere letti ad alta voce dall'inizio alla fine in quarantacinque minuti -un viaggio breve-, sono racconti di persone condotti attraverso una lente speciale sulle loro biografie, i lavori, i fatti privati e i risultati pubblici.Il progetto grafico è a cura dello Studio Sonnoli.IL POSTO DELLE PAROLEascoltare fa pensarewww.ilpostodelleparole.itDiventa un supporter di questo podcast: https://www.spreaker.com/podcast/il-posto-delle-parole--1487855/support.

Welcome to the CRE podcast. 100% Canadian, 100% commercial real estate. Recorded live at the Vancouver Real Estate Forum, this episode of the Commercial Real Estate Podcast features Tim Grant, President of PCI Developments. Hosts  Aaron Cameron and Adam Powadiuk explore how PCI navigates today's volatile market with strategic mixed-use developments, transit-oriented projects, and a... The post Why PCI Is Betting Big on Vancouver's Real Estate Future with Tim Grant, President of PCI Developments appeared first on Commercial Real Estate Podcast.

Claudio Caprara"Fischiava il vento"Una storia sentimentale del comunismo italianoBompiani Editorewww.bompiani.itPassaggi Festival, FanoMer 25 Giugno 2025 – Orario: 18:15 - 19:15 – Luogo: Fano – Piazza MarcoliniCLAUDIO CAPRARA, “Fischiava il vento. Una storia sentimentale del comunismo italiano” (Bompiani, 2025)Conversa con Marino Sinibaldi (Saggista), Nando dalla Chiesa (Sociologo, Presidente Com. Scientifico Passaggi)“Senza un istante di sosta per guardare dentro di sé, tutta presa dal combattimento senza nulla di personale”: così nell'estate del 1946 Palmiro Togliatti descrive la propria vita a Nilde Iotti, il cui amore gli ha restituito il desiderio di tenere qualcosa per sé, salvandolo dalla dedizione assoluta al partito. Quella di Togliatti e Iotti è solo una delle tante vicende di una straordinaria storia collettiva che ha segnato il nostro Novecento: quella del Pci e dei suoi militanti. Il comunismo italiano è stato un'esperienza unica, capace di interpretare gli aspetti più autentici e carichi di speranza rivoluzionaria della sua ideologia fondativa senza doverne sperimentare le tragiche degenerazioni. Una causa a cui una moltitudine di donne e uomini si è votata con passione assoluta. Dalle origini, quando socialismo, comunismo e fascismo per un fatale istante si sfiorano, alle figure più e meno note di Antonio Gramsci e Anselmo e Andrea Marabini, Nicola Bombacci e Veraldo Vespignani; dal biennio rosso del 1919-20 e la nascita del Partito comunista d'Italia nel 1921 fino alla morte di Berlinguer nel 1984. E ancora: la scuola delle Frattocchie e le feste dell'Unità, gli amori e i tradimenti, la propaganda e i funerali. Claudio Caprara – nato in una sezione di partito nella rossa Imola – evoca in queste pagine i luoghi, i miti, i riti che hanno reso quella del comunismo italiano una stagione irripetibile e ci regala un viaggio per istantanee nella storia di un partito che ha lasciato un'impronta profonda nella vita del nostro paese.Claudio Caprara è nato il 21 gennaio (la stessa data della fondazione del PCI) quarant'anni prima del 2000, in una sezione del Partito comunista italiano. Ha lavorato per la FGCI (Federazione giovanile comunista italiana) a livello locale, regionale e nazionale. Ha diretto un settimanale a Imola e ne ha fondato un altro a Faenza. Ha collaborato con Massimo D'Alema in via delle Botteghe Oscure e a Palazzo Chigi. In seguito si è occupato del primo motore di ricerca italiano, poi di televisione. Ama fare fotografie. Dal 2004 è membro del cda di Cinemovel Foundation, un'organizzazione che porta il cinema nelle zone dove non c'è più o dove non è mai arrivato. Nel 2009 ha lavorato con Luca Sofri alla costituzione della società Il Post srl e, dal 2010, ne è consigliere di amministrazione.IL POSTO DELLE PAROLEascoltare fa pensarewww.ilpostodelleparole.itDiventa un supporter di questo podcast: https://www.spreaker.com/podcast/il-posto-delle-parole--1487855/support.

DESCRIPTION Hospitality executive Russell Harms spent three decades working in upscale hotels and overseeing large scale parking management operations across the United States. As his career grew, he began to experience excruciating anxiety and depression, forcing him to navigate unimaginable adversity. As he tried to balance a prosperous career and young family, his world crumbled around him. In this gripping memoir, Harms shares the unseen challenges behind his journey with bipolar and the profound process of reclaiming his life. Discover how he confronted his darkest moments and found the strength to rebuild, offering hope and inspiration for anyone facing their own struggles. This is a story of resilience, redemption, and the power of the human spirit. SPONSORS This episode is brought to you by Parkalytics. Parkalytics will take drone images of parking lots and/or on-street parking for a given time period and then upload those images into their parkalytics software. Within a matter of seconds, it will provide you parking counts, turnover studies, utilization studies, you name it. You can now wow your clients or supervisors by having a complete snapshot of the parking usage for a fraction of the price of a traditional parking study. Learn more at parkalytics.com. This episode is brought to you by Parking Today and the Parking Today Podcast Network. Learn more at parkingtoday.com/podcast. This episode is brought to you by Parker Technology, the customer experience solution of choice for the parking industry. Their solution puts a virtual ambassador in every lane, to help parking guests pay and get on their way in under a minute. Learn more at parkertechnology.com/parkingpodcast and subscribe to our podcast “Harder Than It Looks: Parking Uncovered.” This episode is brought to you by Scheidt & Bachman USA. Scheidt & Bachmann USA markets state-of-the-art Parking Solutions and Fare Collection Systems: the most innovative and advanced solutions in the US. Learn more at scheidt-bachmann-usa.com. This episode is brought to you by Breeze: Parking Concepts' digital platform that makes the parking experience a Breeze! For more than 50 years, PCI has been proactively managing parking & transportation operations with unparalleled integrity & service. Learn more at parkingconcepts.com. This episode is brought to you by Parkmobile. Parkmobile, a part of EasyPark Group, is the leading provider of smart parking and mobility solutions in North America, using a contactless approach to help millions of people easily find, reserve, and pay for parking on their mobile devices. Learn more about parkmobile.io. WEBSITES AND RESOURCES https://www.parkingcast.com/ https://parkingtoday.com/podcast/ www.parkertechnology.com/parkingpodcast scheidt-bachmann-usa.com parkingconcepts.com parkmobile.io parkalytics.com russellharms.com MERCH Check out some of our awesome parking themed t-shirts and other merch at parkingcast.com/swag. MUSEUM Check out some of our artifacts from the world's first parking museum at parkingcast.com/museum.

Contributor: Taylor Lynch, MD Educational Pearls: How do we risk-stratify chest-pain patients? One option is the HEART score This score predicts a patient's 6-week risk of a major adverse cardiac event. Ex. Cath procedure, CABG, PCI, death H stands for History Ask 1) Was the patient diaphoretic? 2) Did they have nausea and/or vomiting? 3) Did the pain radiate down the right or left arm? 4) Was it exertional? Yes to one = one point. Two or more = two points. E stands for EKG One point for left ventricular hypertrophy, t-wave inversions, new bundle-branch blocks. No points for first degree AV block, benign early repolarization, or QT-prolongation Two points for ST-depression A stands for Age >65 gets two points 45-64 gets one point R stands for Risk factors Hypertension, hyperlipidemia, diabetes, obesity, family history, smoking, previous MI, previous CABG, stroke, peripheral arterial disease 1-2 risk factors get 1 point More than two risk factors gets two points T stands for Troponin 1-3x upper limit of normal gets one point >3x upper limit of normal gets two points This gives you a score between zero and ten 0-3 points, patients have a ~2% chance of an adverse event These patients likely go home 4-6 points, patients have a ~20% chance of an adverse event These patients get admitted or expedited outpatient stress test/echo 7-10 points, patients have a ~60% chance of an adverse event Admit and call cardiology. These patients likely get catheterized References Backus BE, Six AJ, Kelder JC, Bosschaert MA, Mast EG, Mosterd A, Veldkamp RF, Wardeh AJ, Tio R, Braam R, Monnink SH, van Tooren R, Mast TP, van den Akker F, Cramer MJ, Poldervaart JM, Hoes AW, Doevendans PA. A prospective validation of the HEART score for chest pain patients at the emergency department. Int J Cardiol. 2013 Oct 3;168(3):2153-8. doi: 10.1016/j.ijcard.2013.01.255. Epub 2013 Mar 7. PMID: 23465250. Laureano-Phillips J, Robinson RD, Aryal S, Blair S, Wilson D, Boyd K, Schrader CD, Zenarosa NR, Wang H. HEART Score Risk Stratification of Low-Risk Chest Pain Patients in the Emergency Department: A Systematic Review and Meta-Analysis. Ann Emerg Med. 2019 Aug;74(2):187-203. doi: 10.1016/j.annemergmed.2018.12.010. Epub 2019 Feb 2. PMID: 30718010. https://www.mdcalc.com/calc/1752/heart-score-major-cardiac-events Summarized by Jeffrey Olson, MS4 | Edited by Jorge Chalit, OMS4 Donate: https://emergencymedicalminute.org/donate/

Score Values: Keri Drew, a PCI certified parent coach full 624 Sun, 22 Jun 2025 13:41:27 +0000 WaXZrzGOO5f4zhBxKGh6qO8sYHGCc3rN sports Best of 670 The Score sports Score Values: Keri Drew, a PCI certified parent coach Best of the Score brings listeners the best interviews, segments, bits and highlights of the station's many shows, including Mully & Haugh, Bernstein & Harris and Spiegel & Holmes. 2024 © 2021 Audacy, Inc. Sports False https://player.amperwavepodcasting.com?

Alla fine della Seconda guerra mondiale, l'Europa fu attraversata da un'ondata di violenze e omicidi illegali. L'intensità e le modalità variarono da paese a paese, ma ovunque lasciarono un segno profondo. In Italia si contarono circa 8.000 vittime, anche se una stima precisa è difficile da fare. Nelle prime settimane dopo la Liberazione regnava l'incertezza: il PCI non aveva ancora una linea chiara su come affrontare le tante esecuzioni sommarie che si moltiplicavano. Ma non furono solo i comunisti a farsi giustizia da soli: anche i socialisti e i partigiani di Giustizia e Libertà furono coinvolti in queste dinamiche. L'amnistia voluta dal ministro della Giustizia, Palmiro Togliatti, coprì molti reati politici commessi fino al 31 luglio 1945, e segnò un tentativo di pacificazione nazionale e di mettere fine alle vendette e agli episodi di violenza illegale. Tuttavia, il clima restò teso a lungo. Dopo l'attentato a Togliatti del 14 luglio 1948, iniziò una repressione sistematica contro chi aveva fatto parte della Resistenza: presero il via i grandi processi contro i partigiani e si aprì una lunga stagione di epurazioni nelle fabbriche e arresti dei militanti comunisti con un tentativo di mettere fuori legge il PCI. Quando si parla degli omicidi avvenuti in Italia dopo il 25 aprile 1945, si usa spesso – per convenzione – l'espressione “Triangolo della morte” o “Triangolo rosso” per indicare quanto accadde nelle province di Reggio Emilia, Modena e Bologna. Non perché tutto si sia limitato a quelle zone, ma perché è lì che si concentrarono i casi più controversi e meglio documentati. Learn more about your ad choices. Visit megaphone.fm/adchoices

Alla fine della Seconda guerra mondiale, l'Europa fu attraversata da un'ondata di violenze e omicidi illegali. L'intensità e le modalità variarono da paese a paese, ma ovunque lasciarono un segno profondo. In Italia si contarono circa 8.000 vittime, anche se una stima precisa è difficile da fare. Nelle prime settimane dopo la Liberazione regnava l'incertezza: il PCI non aveva ancora una linea chiara su come affrontare le tante esecuzioni sommarie che si moltiplicavano. Ma non furono solo i comunisti a farsi giustizia da soli: anche i socialisti e i partigiani di Giustizia e Libertà furono coinvolti in queste dinamiche. L'amnistia voluta dal ministro della Giustizia, Palmiro Togliatti, coprì molti reati politici commessi fino al 31 luglio 1945, e segnò un tentativo di pacificazione nazionale e di mettere fine alle vendette e agli episodi di violenza illegale. Tuttavia, il clima restò teso a lungo. Dopo l'attentato a Togliatti del 14 luglio 1948, iniziò una repressione sistematica contro chi aveva fatto parte della Resistenza: presero il via i grandi processi contro i partigiani e si aprì una lunga stagione di epurazioni nelle fabbriche e arresti dei militanti comunisti con un tentativo di mettere fuori legge il PCI. Quando si parla degli omicidi avvenuti in Italia dopo il 25 aprile 1945, si usa spesso – per convenzione – l'espressione “Triangolo della morte” o “Triangolo rosso” per indicare quanto accadde nelle province di Reggio Emilia, Modena e Bologna. Non perché tutto si sia limitato a quelle zone, ma perché è lì che si concentrarono i casi più controversi e meglio documentati. Learn more about your ad choices. Visit megaphone.fm/adchoices

Ragnhild Ørstavik deler siste nytt fra andre vitenskapelige tidsskrifter. Det nye vaksinerådet i USA vekker bekymring (1, 2). Flere utredes for ADHD, men betyr det at ADHD-forekomsten har gått opp (3, 4)? Et KI-verktøy ser ut til å klare å skille tidlig Parkinson fra lignende sykdommer med god presisjon (5, 6). Hvilken oksygenmetning gir det beste utfallet hos pasienter som får mekanisk ventilasjon (7, 8)? Og hva slags platehemmere gir best langtidsbeskyttelse etter perkutan koronar intervensjon (PCI) (9, 10)? Kinesiske forskere har dyrket et hybridhjerte av menneske og gris i griseembryoer – kanskje vil dette åpne opp for nye transplantasjonsmetoder i fremtiden (11). Alkohol tar 800 000 liv i Europa årlig, hva kan gjøres med det (12)? Og til slutt: JFKs søster, kvinnehelseforskning og hvordan politiske kutt kan ramme alle – uansett kjønn (13, 14). Se hele litteraturlista her: https://tidsskriftet.no/2025/06/podkast/redaktorens-hjorne-89-flere-adhd-utredninger-kunstig-intelligens-og-parkinsons-sykdom-politisk Tilbakemeldinger kan sendes til stetoskopet@tidsskriftet.no.      Stetoskopet produseres av Helena Heimer Rognstad, Are Brean, Ragnhild Ørstavik og Julie Didriksen ved Tidsskrift for Den norske legeforening. Ansvarlig redaktør er Are Brean.      Jingle og lydteknikk: Håkon Braaten / Moderne mediaCoverillustrasjon: Stephen LeeSee omnystudio.com/listener for privacy information.

In many organizations, security exception management is a manual process, often treated as a simple compliance checkbox. While necessary, this approach can lead to unmonitored configurations that drift from their approved state, creating inconsistencies in an organization's security posture over time. How can teams evolve this process to support modern development without compromising on security?In this episode, Ashish Rajan sits down with security expert Santosh Bompally, Cloud Security Engineering Team Lead at Humana to discuss a practical framework for automating exception management. Drawing on his journey from a young tech enthusiast to a security leader at Humana, Santosh explains how to transform this process from a manual task into a scalable, continuously monitored system that enables developer velocity.Learn how to build a robust program from the ground up, starting with establishing a security baseline and leveraging policy-as-code, certified components, and continuous monitoring to create a consistent and secure cloud environment.Guest Socials -⁠⁠ ⁠Santosh's LinkedinPodcast Twitter - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@CloudSecPod⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠If you want to watch videos of this LIVE STREAMED episode and past episodes - Check out our other Cloud Security Social Channels:-⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Cloud Security Podcast- Youtube⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠- ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Cloud Security Newsletter ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠- ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Cloud Security BootCamp⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠If you are interested in AI Cybersecurity, you can check out our sister podcast -⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ AI Cybersecurity PodcastQuestions asked:(00:00) Introduction(00:39) From Young Hacker to Cybersecurity Pro(02:14) The "Tick Box" Problem with Exception Management(03:17) Exposing Your Threat Landscape: The Risk of Not Automating(05:43) Where Do You Even Start? The First Steps(08:26) VMs vs Containers vs Serverless: Is It Different?(11:15) Building Your Program: Start with a Security Baseline(14:44) What Standard to Follow? (CIS, PCI, HIPAA)(17:20) The Lifecycle of a Control: When Should You Retire One?(19:42) The 3 Levels of Security Automation Maturity(23:25) Do You Need to Be a Coder for GRC Automation?(26:16) Fun Questions: Home Automation, Family & Food

The goal of CPR is to keep the brain and vital organs perfused until return of spontaneous circulation (ROSC) is achieved.Post-arrest care and recovery are the final two links in the chain of survival.Identification of ROSC during CPR.Initial patient management goals after identifying ROSC.The patient's GCS/LOC should be evaluated to determine if targeted temperature management (TTM) is indicated.Patients that cannot obey simple commands should receive TTM for at least 24 hours.Recently published studies on TTM and ACLS's current standard.Monitoring the patient's core temperature during TTM.Patients can undergo EEG, CT, MRI, & PCI while receiving TTM.Good luck with your ACLS class!Links: Buy Me a Coffee at https://buymeacoffee.com/paultaylor Practice ECG rhythms at Dialed Medics - https://dialedmedics.com/Free Prescription Discount Card - Download your free drug discount card to save money on prescription medications for you and your pets: https://safemeds.vipPass ACLS Web Site - Episode archives & other ACLS-related podcasts: https://passacls.com@Pass-ACLS-Podcast on LinkedIn

DESCRIPTION Kathleen Federici, Vice President of Professional Development at IPMI, discusses the transition from CAPP to PTMP. SPONSORS This episode is brought to you by Parking Today and the Parking Today Podcast Network. Learn more at parkingtoday.com/podcast. This episode is brought to you by Parker Technology, the customer experience solution of choice for the parking industry. Their solution puts a virtual ambassador in every lane, to help parking guests pay and get on their way in under a minute. Learn more at parkertechnology.com/parkingpodcast and subscribe to our podcast “Harder Than It Looks: Parking Uncovered.” This episode is brought to you by Scheidt & Bachman USA. Scheidt & Bachmann USA markets state-of-the-art Parking Solutions and Fare Collection Systems: the most innovative and advanced solutions in the US. Learn more at scheidt-bachmann-usa.com. This episode is brought to you by Breeze: Parking Concepts' digital platform that makes the parking experience a Breeze! For more than 50 years, PCI has been proactively managing parking & transportation operations with unparalleled integrity & service. Learn more at parkingconcepts.com. This episode is brought to you by Parkmobile. Parkmobile, a part of EasyPark Group, is the leading provider of smart parking and mobility solutions in North America, using a contactless approach to help millions of people easily find, reserve, and pay for parking on their mobile devices. Learn more about parkmobile.io. This episode is brought to you by Parkalytics. Parkalytics will take drone images of parking lots and/or on-street parking for a given time period and then upload those images into their parkalytics software. Within a matter of seconds, it will provide you parking counts, turnover studies, utilization studies, you name it. You can now wow your clients or supervisors by having a complete snapshot of the parking usage for a fraction of the price of a traditional parking study. Learn more at parkalytics.com. WEBSITES AND RESOURCES https://www.parkingcast.com/ https://parkingtoday.com/podcast/ www.parkertechnology.com/parkingpodcast scheidt-bachmann-usa.com parkingconcepts.com parkmobile.io parkalytics.com MERCH Check out some of our awesome parking themed t-shirts and other merch at parkingcast.com/swag. MUSEUM Check out some of our artifacts from the world's first parking museum at parkingcast.com/museum.

The chain of survival for ACLS is the same as was learned in your BLS class.The beginning steps of the Cardiac Emergency and Stroke chain of survival.ACLS's timed goals for first medical contact to PCI for STEMI and door-to-needle for ischemic stroke.Characteristics of areas that have significantly better stroke and out-of-hospital cardiac arrest outcomes.Good luck with your ACLS class!Links: Buy Me a Coffee at https://buymeacoffee.com/paultaylor Practice ECG rhythms at Dialed Medics - https://dialedmedics.com/Free Prescription Discount Card - Download your free drug discount card to save money on prescription medications for you and your pets: https://safemeds.vipPass ACLS Web Site - Episode archives & other ACLS-related podcasts: https://passacls.com@Pass-ACLS-Podcast on LinkedIn

Chronic Total Occlusion in 2025   Guest: Gregory Barsness, M.D. Host: Malcolm Bell, M.D.   Chronic (>3 months) complete epicardial coronary obstructive lesions, often referred to as CTOs, are recognized in a large minority of those referred for coronary angiography yet historically represent

Hoy tratamos varios temas con diferentes caracteristicas pero que tienen algo en común, todos representan frentes de lucha del proletariado tanto en Colombia como en el mundo.Continúamos llamando al internacionalismo proletario para enfrentar el genocido, la ocupación y el apartheid en Palestina, igualmente para respaldar la Guerra Popular en la India y la campaña contra la operación Kagaar que ha golpeado al PCI (maoísta) en los últimos meses.Todo esto en el marco de la necesaria lucha contra el capitalismo imperialista y sus guerras.Pero también hablamos de la realidad politica y social en Colombia en el momento actual, donde hechos como el atentado a Miguel Uribe y las posiciones reaccionarias del Senado y los partidos de derecha no estan aislados. Realidad que reafirma que se requiere fortalecer aun más la lucha independiente contra el Estado y contra los enemios del pueblo.Bienvenidos una vez más a Vanguardia Obrera.Apóyanos comentando, compartiendo el episodio y si quieres, también con una donación.Ingresa a:https://revolucionobrera.com/apoyanos/

What You'll Learn:Why technology may be increasing workplace isolation, not solving itHow EQ is overtaking IQ as the most valuable skill in a tech-driven economyThe four essential factors that drive employee engagementPractical strategies for building stronger relationships with remote teamsWhy work-life integration beats the myth of work-life balanceWhat great leaders do differently to retain top talentInsights from over 90,000 professionals in 20+ countriesKey Quote:“You'll never grow as a company if you're too busy replacing workers.”Resources & Mentions:Dan's book: Back to Human: How Great Leaders Create Connection in the Age of IsolationDan's podcast: Five Questions with Dan SchawbelVisit DanSchawbel.com for more Subscribe & Review:If you enjoyed this episode, please leave a review and subscribe to The Burleson Box on Apple Podcasts, Spotify, or wherever you listen. Your support helps us bring powerful conversations like this to more listeners in healthcare leadership. ***The Burleson Box is brought to you by Stax Payments:Save Big on Transaction Fees: Boost Your Bottom Line with Stax Payments.Did you know that your practice can start saving thousands of dollars on your monthly processing costs with our preferred payments partner, Stax? Simplify your practice operations and provide a quality patient experience. Healthcare practices like yours need a way to accept payments simply and securely. That's where Stax comes in.Stax helps you manage your entire payments experience from within one platform. You can safely accept touch-free payments in-person, online, or over the phone, securely store and manage patient information with layered security and Level 1 PCI compliance.
Take advantage of a simpler, more transparent way to process your payments with competitive flat-rate pricing, provided exclusively through Stax. No additional fees or contracts required!Power your practice and get paid faster with simple, safe and secure payment solutions. Have questions? Schedule time to speak with a dedicated payment consultant to learn more.Click Below to Lear More Today:StaxPayments.com/burleson-seminars*** Go Premium: Members get early access, ad-free episodes, hand-edited transcripts, exclusive study guides, special edition books each quarter, powerpoint and keynote presentations and two tickets to Dustin Burleson's Annual Leadership Retreat.http://www.theburlesonbox.com/sign-up Stay Up to Date: Sign up for The Burleson Report, our weekly newsletter that is delivered each Sunday with timeless insight for life and private practice. Sign up here:http://www.theburlesonreport.com Follow Dustin Burleson, DDS, MBA at:http://www.burlesonseminars.com

Smart CIOs Do This: The Unspoken Rules of Cybersecurity Leadership with Guest: Andrew Griffiths, CEO & Founder of Annexus TechnologiesHost: Julie RigaAbout This EpisodeIn this episode, Julie sits down with Andrew Griffiths, a legacy-minded CEO and founder of Annexus Technologies, a multinational IT firm known for building infrastructure so strong it rarely needs fixing. Andrew is a strategist, philosopher of security, and storyteller with a deep belief in designing systems that protect people, not just profits.Together, they dive deep into the three essential ingredients for CIO success and explore the unspoken rules of cybersecurity leadership that smart CIOs follow to protect their organizations.Guest BackgroundAndrew Griffiths is the CEO and founder of Annexus Technologies, a cybersecurity firm registered in Jamaica since 2014, now expanding into Canada. Andrew's unique perspective on IT infrastructure was shaped by early exposure to satellites, electronics, and various technologies, leading him to see IT as ubiquitous and transformative. His philosophy centers on optimizing existing systems and connecting people through technology.Fun Fact: Andrew's favorite food is ackee and corned pork - a unique twist on Jamaica's national dish that substitutes corned pork for the traditional saltfish.Key Topics DiscussedThe Three Ingredients for CIO Success:1 Visibility & AssessmentUnderstanding what's happening both inside and outside your networkThe importance of secure design for internal and external domainsImplementing layers of trust with zero-trust principles2 Proactive Analysis & PlanningMoving from prevention to proactivityUnderstanding your cybersecurity posture rating (0-100)Identifying compromised credentials on the dark webCreating mitigation plans for when breaches occur3 Strategic ImplementationBalancing cost-effectiveness with security requirementsPlanning for short-term, medium-term, and long-term security needsAligning business objectives with IT infrastructureThe Annexus Approach:Public Domain Assessments: Understanding external security postureMulti-standard Compliance: Meeting GDPR, PIPEDA, PCI, and other international standardsProactive Monitoring: Real-time detection of network scanning attemptsVirtual Network Infrastructure: Creating controlled environments for threat analysisKey Insights for CIOsThe Trust-Building Challenge:Cybersecurity sales cycles can take 6 months to a year due to trust requirementsBuilding relationships requires patience and consistent educationSometimes you need to wait for organizations to validate the need themselvesThe Titanic Analogy:Andrew compares cybersecurity professionals to engineers warning about icebergs - often dismissed until disaster strikes, highlighting the importance of persistent, consistent communication about security risks.Multi-Vendor Security Strategy:Avoid vendor lock-in for critical security infrastructureUse different firewall platforms in series to increase security complexityDesign solutions that make it harder for attackers to predict your security stackFuture-Forward ThinkingNext-Generation Platforms:Annexus is focusing on comprehensive ecosystems that protect:Data within organizationsData transfer between organizationsCloud redundancy strategies across multiple providers (Azure, AWS)The Future of IT:Andrew predicts the future lies in "redundancy at cloud scale" - ensuring business continuity even when major cloud providers experience outages.Connect with Andrew GriffithsWebsite: www.annexustech.caSocial Media: Available on YouTube, Twitter, Instagram, FacebookCompany: Annexus TechnologiesConnect with Julie RigaWebsite: www.julieriga.comSocial Media: www.linkedin.com/in/julierigaCoaching: Learn more about leadership coaching and transformationThis episode is perfect for sharing with CIOs and IT leaders in your network who need to hear these insights about modern cybersecurity leadership.

Dive deep into the world of cloud security with Rocky Giglio and special guest Sean Atkinson, CISO at the Center for Internet Security (CIS), on this episode of Cloud and Clear! We examine the crucial role of CIS benchmarks and hardened images in establishing a robust and secure cloud infrastructure. In this insightful discussion, Sean breaks down: ✅ What CIS is and its mission to create a safer connected world. ✅ The evolution of CIS Controls from 20 to 18 for greater efficiency. ✅ Understanding CIS Benchmarks and how they standardize security configurations. ✅ The power of Hardened Images: Start secure from day zero in your cloud environment. ✅ Shifting security left and proactively integrating security into design. ✅ How CIS simplifies compliance with NIST, PCI, HIPAA, and other frameworks. ✅ The importance of community and partnership in cybersecurity. Whether you're a security professional, cloud engineer, or anyone concerned about keeping data safe in the cloud, this episode is packed with valuable knowledge. Learn how to leverage CIS resources to strengthen your security posture and simplify compliance. Tune in to discover how CIS is making cloud security more accessible and effective! Don't forget to subscribe to Cloud and Clear for more expert insights on cloud transformation. #CloudSecurity #CIS #Cybersecurity #CloudComputing #HardenedImages #SecurityBenchmarks #CloudAndClear #GoogleCloud #Compliance #NIST #PCI #HIPAA #CISO #TechPodcast Join us for more content by liking, sharing, and subscribing!

In this latest episode of the PCI podcast, David Thompson, Secretary of PCI's Council for Congregational Life and Witness talks with Gary Millar, Principal of Queensland Theological College in Brisbane, Australia about his recent book called Both/And Ministry: Living and leading like Jesus'. Present is a denomination wide initiative inviting and encouraging congregations and their members to make themselves fully present to God who is ever present to us. Find out more and watch a video about the Present initiative here www.presbyterianireland.org/present

Brandon Payne, executive director for the National Council on School Facilities, joins this month's episode of Security Management Highlights to discuss how to integrate security and safety into school facility planning and funding during both retrofits and new builds. Then, Kevin Jones, CPP, PCI, addresses key considerations for arming security professionals, from legal liability to insurance to continuous training. Additional Resources Read more from Brandon Payne about school facility management and where security and safety fit in here: https://www.asisonline.org/security-management-magazine/articles/2025/04/k12/school-facilities-managers/ Meet many of the other essential partners in school safety and security in this Security Management series: https://www.asisonline.org/security-management-magazine/articles/2025/04/k12/ Want to help drive school security forward? Keep an eye out for the forthcoming ASIS International School Security Standard. Learn more here: https://www.asisonline.org/publications--resources/news/blog/2024/press-briefing-school-security-standard/ Read more about arming security teams in the June issue of Security Technology: https://www.asisonline.org/security-management-magazine/monthly-issues/security-technology/archive/2025/june/ Hear more from Kevin Jones, CPP, PCI, in his latest article about considerations for selecting the right weapons for security: https://www.asisonline.org/security-management-magazine/monthly-issues/security-technology/archive/2025/june/how-to-make-a-weapon-selection-when-arming-your-security-team/

DESCRIPTION Dan Mathers, Co-Founder, President & CEO of eleven-x, and Melissa McMahon, Parking and Curbspace Manager with the Arlington County Department of Environmental Services discuss Arlington County's one-of-a-kind parking project. Part Two. SPONSORS This episode is brought to you by Parking Today and the Parking Today Podcast Network. Learn more at parkingtoday.com/podcast. This episode is brought to you by Parker Technology, the customer experience solution of choice for the parking industry. Their solution puts a virtual ambassador in every lane, to help parking guests pay and get on their way in under a minute. Learn more at parkertechnology.com/parkingpodcast and subscribe to our podcast “Harder Than It Looks: Parking Uncovered.” This episode is brought to you by Scheidt & Bachman USA. Scheidt & Bachmann USA markets state-of-the-art Parking Solutions and Fare Collection Systems: the most innovative and advanced solutions in the US. Learn more at scheidt-bachmann-usa.com. This episode is brought to you by Breeze: Parking Concepts' digital platform that makes the parking experience a Breeze! For more than 50 years, PCI has been proactively managing parking & transportation operations with unparalleled integrity & service. Learn more at parkingconcepts.com. This episode is brought to you by Parkmobile. Parkmobile, a part of EasyPark Group, is the leading provider of smart parking and mobility solutions in North America, using a contactless approach to help millions of people easily find, reserve, and pay for parking on their mobile devices. Learn more about parkmobile.io. This episode is brought to you by Parkalytics. Parkalytics will take drone images of parking lots and/or on-street parking for a given time period and then upload those images into their parkalytics software. Within a matter of seconds, it will provide you parking counts, turnover studies, utilization studies, you name it. You can now wow your clients or supervisors by having a complete snapshot of the parking usage for a fraction of the price of a traditional parking study. Learn more at parkalytics.com. WEBSITES AND RESOURCES https://www.parkingcast.com/ https://parkingtoday.com/podcast/ www.parkertechnology.com/parkingpodcast scheidt-bachmann-usa.com parkingconcepts.com parkmobile.io parkalytics.com https://www.arlingtonva.us/Government/Programs/Transportation/Parking/Performance-Parking-Pilot https://eleven-x.com/ MERCH Check out some of our awesome parking themed t-shirts and other merch at parkingcast.com/swag. MUSEUM Check out some of our artifacts from the world's first parking museum at parkingcast.com/museum.

Episode Topic: Ruston Miles of Bluefin joins PayPod to unravel the real story behind payment data security. From debunking myths around chip card protection to highlighting the need for encryption at the point of interaction, Ruston shares critical insights into why businesses must adopt P2P encryption and tokenization to stay ahead of evolving threats. Lessons You'll Learn: How to distinguish fraud prevention from data security, the necessity of protecting data at the entry point, why chips don't equal encryption, and how upcoming technologies like quantum computing and AI are reshaping the threat landscape. About Our Guest: Ruston Miles is the Founder and Chief Strategy Officer at Bluefin, a payment security company that pioneered PCI-validated point-to-point encryption. With decades of experience in cybersecurity, Ruston has been instrumental in setting encryption standards adopted by Visa, Mastercard, and global universities. He's also a strong advocate for tokenization, quantum-resistant encryption, and secure digital wallets. Topics Covered: The difference between fraud and data breaches   How P2P encryption protects data before it can be stolen   Why EMV chips give a false sense of security   Storing tokens instead of real card numbers   Security challenges in higher education and enterprise   Quantum computing's potential threat to public key encryption

In this industry-sponsored episode, host Praveen Ranganath, MD is joined by Yader Sandoval, MD and Jonathon Leipsic, MD, MSCCT, the chair and co-chair of the recently published inter-society roundtable document on CCTA for PCI planning. Conversation topics include the origin of this expert roundtable, the benefits of and evidence supporting CCTA for PCI planning, a deep-dive into heavily calcified and bifurcation lesion planning, and insights on how to tackle current barriers to adoption. Coronary Computed Tomography Angiography to Guide Percutaneous Coronary Intervention: Expert Opinion from a SCAI/SCCT RoundtableThis episode is sponsored by Heartflow. References to a specific product, process, or service by speakers in this podcast episode do not constitute or imply an endorsement by the Society of Cardiovascular Computed Tomography. The views and opinions expressed in do not necessarily reflect those of the Society of Cardiovascular Computed Tomography.

Lancet 1999;353:2001-07Background: Beta-blockers directly reduce cardiac contractility and myocardial oxygen demand. For decades, they were avoided in patients with acute and chronic heart failure over concerns they would facilitate decompensation of the condition. The therapeutic cornerstones of treatment, prior to the modern era of clinical trials, focused on managing symptoms and quality of life with diuretics and inotropic agents like digoxin; however, new paradigms were arising that focused on addressing neurohormonal mechanisms of chronic disease that were over-activated in the failing heart. The first major success came with inhibition of the renin angiotensin aldosterone system with angiotensin converting enzyme inhibitors whose effect on mortality for patients with mild and severe forms of chronic heart failure were demonstrated in the V-HEFT II, CONSENSUS, and SOLVD trials. Additional benefits were demonstrated with the mineralocorticoid receptor antagonist spironolactone in the RALES trial. These drug classes primarily work by reducing afterload and volume retention. Appreciating why they work for improving cardiac performance and managing symptoms in heart failure patients is straightforward when we consider the major factors that effect cardiac stroke volume - preload, afterload and contractility; however, it is also noteworthy the effects these agents have on sudden death. How beta-blockade benefits the failing heart is less obvious (outside prevention of sudden death). Mechanistic studies in patients with chronic heart failure have consistently shown that when beta blockers are used for more than 1 month, left ventricular function improves. Beta blocker therapy appears to restore the density of beta-adrenergic receptors after they have been downregulated by the chronic overactivity of the sympathetic nervous system. The first major placebo-controlled RCT to demonstrate a mortality benefit used the non-selective beta blocker carvedilol. The trial was small and not originally designed to test mortality and was stopped early without clearly predefined stopping rules. Furthermore, 8% of total patients selected for participation in the trial were excluded prior to randomization after a 2 week, open-label run-in phase with the study drug, which saw 2% of all patients experience worsening heart failure or death representing 24 patients (the difference in total deaths between groups was 9 when the trial was stopped). The Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF) was the first large scale trial designed to test the hypothesis that beta-blockade with metoprolol controlled/extended release (CR/XL) added to optimum medical therapy reduces mortality in patients with chronic systolic heart failure.Patients: Patients were recruited from 313 sites in 13 European countries and the United States. Eligible patients were men and women between the age of 40 to 80 years with symptomatic heart failure (NYHA class II-IV) for >/= 3 months before randomization. They had to be on a diuretic and ACE inhibitor for at least 2 weeks. Other drugs, including digoxin, could also be used. Patients also had to have an EF of /=68 beats per minute.Patients were excluded if: they had an MI or unstable angina within 28 days; had an indication or contraindication for treatment with beta-blocker; beta blockade within 6 weeks; heart failure due to systemic disease (i.e., amyloidosis) or alcohol abuse; scheduled or performed cardiac transplant; an ICD; procedures such as CABG or PCI planned or performed in the past 4 months; 2nd or 3rd degree AV block unless a pacemaker was present; unstable or decompensated heart failure defined by pulmonary edema or hypoperfusion or supine systolic BP 25% deviation of the number of observed versus expected consumed placebo tablets during the run-in period.Baseline characteristics: The mean age of patients was 64 years and approximately 78% were male. Slightly more than 30% of patients were above the age of 70. The average EF was 28%. The average SBP was 130 mmHg and heart rate was 82 bpm. Most patients had mild to moderate heart failure, with 41% in NYHA Class II, 56% in Class III, and only 3% in Class IV. Ischemic cardiomyopathy accounted for 65% of cases and nonischemic causes accounted for 35%. Most patients were on an ACE inhibitor or ARB (95%) and diuretic (90%). Digoxin was used in 63%. Trial procedures: Prior to randomization, the study was preceded by a single-blind, 2-week placebo run-in period. Patients meeting eligibility were then randomized to placebo or metoprolol CR/XL. The starting dose of placebo or metoprolol CR/XL was 12.5 mg daily for patients in NYHA class III or IV and 25 mg daily for patients in NYHA class II. The dose was doubled every 2 weeks until the target dose of 200 mg daily was reached. Patients were followed every 3 months.Endpoints: The primary outcome was all-cause mortality. It was estimated that 3,200 patients would need to be followed for 2.4 years to detect a 30% relative reduction in mortality based on annual mortality rate of 9.4% in the placebo group. This would achieve at least 80% power with a 2-sided alpha of 0.04. Patients were recruited faster then planned and so the final sample size of 3,991 patients increased the power of the study.The study was monitored by an independent safety committee and predefined stopping rules for efficacy were based on all-cause mortality, done when 25%, 50%, and 75% of expected deaths had occurred. Results: The trial was stopped early after the 2nd preplanned interim analysis when 50% of expected deaths had occurred. The mean duration of follow-up at the time of stopping was 1 year. The mean daily dose of metoprolol CR/XL was 159 mg once daily, with 87% receiving 100 mg or more and 64% receiving the target dose of 200 mg daily. In the placebo group, the corresponding values were 179 mg daily, 91% and 82%. The study drug was discontinued permanently in 14% of patients in the metoprolol group and 15% in the placebo group. Six months after randomization, heart rate decreased by 14 bpm in the metoprolol group compared to only 3 bpm in the placebo group. Systolic blood pressure decreased less in the metoprolol group (-2.1 vs 3.5 mmHg).Compared to placebo, metoprolol significantly reduced all-cause mortality (7.3% vs 10.8%; RR 0.66; 95% CI 0.53—0.81). Cardiovascular mortality accounted for 91% of all deaths; with sudden death accounting for 58% and death from worsening heart failure accounting for 24% of all deaths. All 3 of these causes of death were significantly reduced by metoprolol. The relative and absolute effects on death were greatest for patients with NYHA class III heart failure.Conclusions: In this trial of stable patients with mild to moderate chronic systolic heart failure, who were optimized on an ACEi or ARB and diuretic, metoprolol CR/XL significantly reduced all-cause mortality. Approximately 30 patients would need to be treated with metoprolol compared to placebo for 1 year to prevent 1 death. This trial represents a significant win for beta blockade in patients with chronic systolic heart failure. While the NNT in this trial is slightly higher than in SOLVD, it is important to appreciate that follow-up time in SOLVD was more than 3x longer. Limitations to external validity in this trial include the run-in period and stringent inclusion and exclusion criteria. Our enthusiasm is also tempered by early stopping, which has been found to be associated with false positive or exaggerated results but this concern is mitigated to some extent in this trial because the rules for early stopping were clearly defined in the protocol.Cardiology Trial's Substack is a reader-supported publication. To receive new posts and support our work, consider becoming a free or paid subscriber. Get full access to Cardiology Trial's Substack at cardiologytrials.substack.com/subscribe

In a SlatorPod first, four guests — Scott Cooper, CEO of Language Services Associates (LSA), Pablo Tercero, COO of LSA, Jerry Song, CEO of Lingolet, and Edward Varela, VP of Business Development at Lingolet — shared their insights into a newly forged partnership.Scott explained that the decision to partner instead of building an in-house AI solution allowed LSA to stay focused on its core strengths while leveraging Lingolet's technical edge. The alliance goes beyond a vendor agreement, with LSA taking an equity stake in Lingolet, anchoring the relationship in shared strategy and long-term commitment. For Jerry and Edward, the partnership is a natural progression, rooted in their deep knowledge of both software development and the language services market.In a standout use case, the two companies helped a Major League Soccer team enable multilingual, AI-assisted communication in coaching sessions — bridging language gaps in real time for international players.On the tech front, Jerry and Edward explained that Lingolet doesn't build large language models from scratch but instead acts as an orchestrator, offering clients the ability to customize and deploy AI tools within secure, dedicated environments. Pablo underscored LSA's HIPAA and PCI compliance, as security, compliance, and privacy are essential pillars, especially in regulated sectors like healthcare.Looking ahead, LSA and Lingolet are preparing to offer hybrid solutions where AI can bridge the gap during interpreter unavailability, even for brief moments, potentially transforming session wait times. Their roadmap includes broader language coverage, deeper integration with healthcare platforms, and innovative pricing models that will reshape how interpretation services are sold and scaled.

In the latest JACC offering from EuroPCR, JACC Associate Editor Celina M. Yong, MD, FACC, interviews Dr. Ashkan Eftekhari, PhD, to discuss insights into his study, Biolimus-Eluting Biomatrix Stent Versus a Dual-Therapy Sirolimus-Eluting Stent in PCI: SORT OUT XI Randomized Trial. The biolimus A9-eluting BioMatrix Alpha stent (BES), has not been compared with another contemporary drug eluting stent. This study compared one-year target lesion failure (TLF) in BES versus the dual-therapy sirolimus-eluting Combo stent (DTS) in an all-comer population undergoing PCI. A total of 3,136 patients were randomized 1:1 to either BES or DTS. The primary result showed that BES was non-inferior to DTS. Additionally, there was a significantly higher rate of definite stent thrombosis in the BES arm. In conclusion, BES was non-inferior to DTS at one-year follow-up with respect to the primary endpoint, TLF.

The chain of survival for a cardiac emergency and stroke start the same:1. preparedness & recognition of an emergency;2. activation of EMS;3. delivery of Advanced Life Support; and4. transporting to the most appropriate facility.ALS ambulances are staffed with paramedics who have training in ACLS skills.Why EMS "Destination Protocols" for suspected stroke and STEMI make a difference.ACLS's timed benchmarks for:point of first medical contact to PCI for ST elevation MI;door to tPA for ischemic stroke; andonset of symptoms to EVT for LVO strokes.Why EMS should bypass a close hospital to transport a STEMI or suspected stroke patient to a hospital capable of 24/7 PCI or a certified stroke center.Check out the Pod Resource page at passacls.com for links to the "EMS On Air" podcast for links to episodes that look at EMS's role in stroke outcomes in the rural vs urban area.Good luck with your ACLS class!Links: Buy Me a Coffee at https://buymeacoffee.com/paultaylor Practice ECG rhythms at Dialed Medics - https://dialedmedics.com/Free Prescription Discount Card - Download your free drug discount card to save money on prescription medications for you and your pets: https://safemeds.vipPass ACLS Web Site - Episode archives & other ACLS-related podcasts: https://passacls.com@Pass-ACLS-Podcast on LinkedIn

In this latest episode of the PCI podcast, Jonny McClune and David Thompson from PCI's Council for Congregational Life and Witness are joined by missiologist David Smith to explore what it looks like for congregations to be present in today's changing communities. Present is a denomination wide initiative inviting and encouraging congregations and their members to make themselves fully present to God who is ever present to us. Find out more and watch a video about the Present initiative here www.presbyterianireland.org/present

Credit card processing fees can eat away at your brewery's profits, but expert Patrick MacLellan from Merchant Cost Consulting shows how you can save an average of 20% on these costs without changing your current processor or disrupting operations.Summary• 3 main fee components: interchange charges from card brands, processor markups, and miscellaneous fees• Why most businesses are overpaying – processing statements are deliberately confusing and contracts often allow price changes without notice• How processors typically adjust pricing three times per year, slowly increasing your costs• The truth about POS systems that bundle processing with their software solutions• How to identify bogus fees like non-PCI compliance charges that can be eliminated• Pros and cons of customer surcharges and how to implement them legally• Contract considerations including early termination fees and auto-renewalsVisit merchantcostconsulting.com to learn more or request a free statement analysis to see potential savings.Sign up for the FREE brewery financial training newsletter.

Marcela Belleza e Raphael Coelho convidam Matheus Rezende, residente do último ano de Cardiologia - Incor, para conversar sobre manejo de doença coronariana crônica em tres tópicos:- Como realizar a investigação inicial?- Como fazer a terapia medicamentosa inicial?- O que fazer com o paciente que não melhora?Referências: 1. Vrints C, Andreotti F, Koskinas KC, et al. 2024 ESC Guidelines for the management of chronic coronary syndromes [published correction appears in Eur Heart J. 2025 Feb 21:ehaf079. doi: 10.1093/eurheartj/ehaf079.]. Eur Heart J. 2024;45(36):3415-3537. doi:10.1093/eurheartj/ehae1772. Virani, Salim S et al. “2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management of Patients With Chronic Coronary Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines.” Circulation vol. 148,9 (2023): e9-e119. doi:10.1161/CIR.00000000000011683. Montone RA, Rinaldi R, Niccoli G, et al. Optimizing Management of Stable Angina: A Patient-Centered Approach Integrating Revascularization, Medical Therapy, and Lifestyle Interventions. J Am Coll Cardiol. 2024;84(8):744-760. doi:10.1016/j.jacc.2024.06.0154. Mortensen MB, Dzaye O, Steffensen FH, et al. Impact of Plaque Burden Versus Stenosis on Ischemic Events in Patients With Coronary Atherosclerosis. J Am Coll Cardiol. 2020;76(24):2803-2813. doi:10.1016/j.jacc.2020.10.0215. Doenst T, Haverich A, Serruys P, et al. PCI and CABG for Treating Stable Coronary Artery Disease: JACC Review Topic of the Week. J Am Coll Cardiol. 2019;73(8):964-976. doi:10.1016/j.jacc.2018.11.0536. Maron DJ, Hochman JS, Reynolds HR, et al. Initial Invasive or Conservative Strategy for Stable Coronary Disease. N Engl J Med. 2020;382(15):1395-1407. doi:10.1056/NEJMoa19159227. Rajkumar CA, Foley MJ, Ahmed-Jushuf F, et al. A Placebo-Controlled Trial of Percutaneous Coronary Intervention for Stable Angina. N Engl J Med. 2023;389(25):2319-2330. doi:10.1056/NEJMoa23106108. Eikelboom JW, Connolly SJ, Bosch J, et al. Rivaroxaban with or without Aspirin in Stable Cardiovascular Disease. N Engl J Med. 2017;377(14):1319-1330. doi:10.1056/NEJMoa17091189. Howlett JG, Stebbins A, Petrie MC, et al. CABG Improves Outcomes in Patients With Ischemic Cardiomyopathy: 10-Year Follow-Up of the STICH Trial. JACC Heart Fail. 2019;7(10):878-887. doi:10.1016/j.jchf.2019.04.01810. Nidorf SM, Fiolet ATL, Mosterd A, et al. Colchicine in Patients with Chronic Coronary Disease. N Engl J Med. 2020;383(19):1838-1847. doi:10.1056/NEJMoa202137211. Boden WE, O'Rourke RA, Teo KK, et al. Optimal medical therapy with or without PCI for stable coronary disease. N Engl J Med. 2007;356(15):1503-1516. doi:10.1056/NEJMoa07082912. Ford TJ, Stanley B, Good R, et al. Stratified Medical Therapy Using Invasive Coronary Function Testing in Angina: The CorMicA Trial. J Am Coll Cardiol. 2018;72(23 Pt A):2841-2855. doi:10.1016/j.jacc.2018.09.00613. Carvalho, Tales de et al. “Brazilian Cardiovascular Rehabilitation Guideline - 2020.” “Diretriz Brasileira de Reabilitação Cardiovascular – 2020.” Arquivos brasileiros de cardiologia vol. 114,5 (2020): 943-987. doi:10.36660/abc.20200407

DESCRIPTION Dan Mathers, Co-Founder, President & CEO of eleven-x, and Melissa McMahon, Parking and Curbspace Manager with the Arlington County Department of Environmental Services discuss Arlington County's one-of-a-kind parking project. SPONSORS This episode is brought to you by Parking Today and the Parking Today Podcast Network. Learn more at parkingtoday.com/podcast. This episode is brought to you by Parker Technology, the customer experience solution of choice for the parking industry. Their solution puts a virtual ambassador in every lane, to help parking guests pay and get on their way in under a minute. Learn more at parkertechnology.com/parkingpodcast and subscribe to our podcast “Harder Than It Looks: Parking Uncovered.” This episode is brought to you by Scheidt & Bachman USA. Scheidt & Bachmann USA markets state-of-the-art Parking Solutions and Fare Collection Systems: the most innovative and advanced solutions in the US. Learn more at scheidt-bachmann-usa.com. This episode is brought to you by Breeze: Parking Concepts' digital platform that makes the parking experience a Breeze! For more than 50 years, PCI has been proactively managing parking & transportation operations with unparalleled integrity & service. Learn more at parkingconcepts.com. This episode is brought to you by Parkmobile. Parkmobile, a part of EasyPark Group, is the leading provider of smart parking and mobility solutions in North America, using a contactless approach to help millions of people easily find, reserve, and pay for parking on their mobile devices. Learn more about parkmobile.io. This episode is brought to you by Parkalytics. Parkalytics will take drone images of parking lots and/or on-street parking for a given time period and then upload those images into their parkalytics software. Within a matter of seconds, it will provide you parking counts, turnover studies, utilization studies, you name it. You can now wow your clients or supervisors by having a complete snapshot of the parking usage for a fraction of the price of a traditional parking study. Learn more at parkalytics.com. WEBSITES AND RESOURCES https://www.parkingcast.com/ https://parkingtoday.com/podcast/ www.parkertechnology.com/parkingpodcast scheidt-bachmann-usa.com parkingconcepts.com parkmobile.io parkalytics.com https://www.arlingtonva.us/Government/Programs/Transportation/Parking/Performance-Parking-Pilot https://eleven-x.com/ MERCH Check out some of our awesome parking themed t-shirts and other merch at parkingcast.com/swag. MUSEUM Check out some of our artifacts from the world's first parking museum at parkingcast.com/museum.

Key Takeaways:AI can be viewed as a necessity for growth to drive both cost savings and revenue growth.Establishing a strong governance framework is crucial for managing risks associated with AI, such as data breaches and compliance with regulations like HIPAA and PCI.AI can be used both reactively to address immediate pain points and proactively to predict and optimize future business operations.While speed and scale are important, startups must ensure they do not compromise on compliance and governance, which are vital for sustainable growth.Developing an AI use policy is a best practice to guide internal and external applications of AI, ensuring responsible and effective usage.

(This episode originally aired on October 22, 2024.) For years, the best word to describe Medicare Advantage (MA) was “untouchable.” Hugely popular among seniors, profitable for health plans—the hybrid public-private payment model grew to the point that it now covers more seniors than traditional Medicare. But in the past few years, the tide has started to change. And if you've been paying attention in recent months, you'll have seen headlines announcing that payers that are scaling back their MA offerings and providers are exiting MA contracts. The MA market has gone from “untouchable” to “volatile.” The question is: why is this happening, and what does it mean for payers, providers, and seniors moving forward? In this episode, hosts Rachel (Rae) Woods and Abby Burns invite health plan experts Max Hakanson and Chelsea Needham to dissect what is going on in MA and how plans and providers are—or should be—navigating the changing tide. Links: Ep. 203: Value series: Is the future of VBC in specialty care? Zing Health & Strive Health say yes. Ep. 149: Senior Care (Part 1): Specialized primary care for an aging population Ep. 150: Senior Care (Part 2): The rapid growth of Medicare Advantage 3 traits health plans want in a provider partner 4 traits providers want in a health plan partner Around the nation: CMS releases Medicare Advantage Star Ratings Q&A: Cardiologist Navin Kapur discusses the future of complex PCI

(This episode originally aired on October 22, 2024.) For years, the best word to describe Medicare Advantage (MA) was “untouchable.” Hugely popular among seniors, profitable for health plans—the hybrid public-private payment model grew to the point that it now covers more seniors than traditional Medicare. But in the past few years, the tide has started to change. And if you've been paying attention in recent months, you'll have seen headlines announcing that payers that are scaling back their MA offerings and providers are exiting MA contracts. The MA market has gone from “untouchable” to “volatile.” The question is: why is this happening, and what does it mean for payers, providers, and seniors moving forward? In this episode, hosts Rachel (Rae) Woods and Abby Burns invite health plan experts Max Hakanson and Chelsea Needham to dissect what is going on in MA and how plans and providers are—or should be—navigating the changing tide. Links: Ep. 203: Value series: Is the future of VBC in specialty care? Zing Health & Strive Health say yes. Ep. 149: Senior Care (Part 1): Specialized primary care for an aging population Ep. 150: Senior Care (Part 2): The rapid growth of Medicare Advantage 3 traits health plans want in a provider partner 4 traits providers want in a health plan partner Around the nation: CMS releases Medicare Advantage Star Ratings Q&A: Cardiologist Navin Kapur discusses the future of complex PCI

In this episode, Dr. Valentin Fuster, provides a concise summary of the May 13, 2025 issue. He discusses four original studies on key cardiovascular topics, including the impact of chronic kidney disease and obesity on heart failure, the role of dobutamine stress echocardiography in predicting PCI outcomes, the effects of empagliflozin on erythropoiesis in heart failure, and the influence of adiposity, insulin resistance, and diabetes in heart failure with preserved ejection fraction. He highlights emerging insights into treatment strategies and ongoing challenges in understanding these complex cardiovascular conditions. Concluding with a separate review on anthracycline cardiotoxicity in cancer patients.

In this podcast, Dr. Valentin Fuster discusses a groundbreaking study from the Orbiter 2 trial, which explores how dobutamine stress echocardiography (DSE) can predict the efficacy of percutaneous coronary intervention (PCI) in relieving angina in patients with stable coronary artery disease. The study reveals that the degree of ischemia, as measured by DSE, is strongly correlated with improvement in symptoms, offering new insights into patient selection for PCI treatment.

In this episode, Dustin Burleson sits down with the powerhouse leadership team behind Rock Dental Brands to answer one of the most pressing questions in modern dentistry and orthodontics: How do I avoid choosing the wrong DSO?You'll hear directly from CEO Kristi Casey, Chief Development Officer Spencer Lunghino, and Co-Founder Dr. Mark Dake as they share a transparent look into the origins, philosophy, and strategic direction of Rock Dental Brands. Together, they bust myths around private equity, clinical autonomy, and growth timelines—and reveal what doctors should really be asking before joining a DSO.If you're a dentist, orthodontist, or specialist considering your next move, this episode is a must-listen. What You'll Learn:The real story behind private equity in dentistry—where the money comes from and how it worksWhy not all DSOs (or equity structures) are created equalHow Rock Dental Brands evolved from a doctor-led support model to a nationally respected DSOThe biggest myths around clinical autonomy, ownership, and growthWhy Rock's equity model is designed to treat doctors fairly—and how that differs from joint venturesHow to reverse-engineer a smart partnership decision using Charlie Munger's “invert and avoid” philosophyWhat questions to ask during DSO due diligence (and how to avoid future regret) Key Quotes:“We were built to be proud of the work we're doing 50 years from now." —Dr. Mark Dake“You're not giving up control of your practice. You're gaining part of 110 practices.” —Kristi Casey Connect with Our Guests:Spencer Lunghino – spencer.lunghino@rockdentalbrands.comrockdentalbrands.com Resources Mentioned:GreyFinch Practice Management SoftwareDentiCon by Planet DDSVistria Group – Private equity partner of Rock Dental Brands Subscribe & Review:If you enjoyed this episode, please leave a review and subscribe to The Burleson Box on Apple Podcasts, Spotify, or wherever you listen. Your support helps us bring powerful conversations like this to more listeners in healthcare leadership. ***The Burleson Box is brought to you by Stax Payments:Save Big on Transaction Fees: Boost Your Bottom Line with Stax Payments.Did you know that your practice can start saving thousands of dollars on your monthly processing costs with our preferred payments partner, Stax? Simplify your practice operations and provide a quality patient experience. Healthcare practices like yours need a way to accept payments simply and securely. That's where Stax comes in.Stax helps you manage your entire payments experience from within one platform. You can safely accept touch-free payments in-person, online, or over the phone, securely store and manage patient information with layered security and Level 1 PCI compliance.
Take advantage of a simpler, more transparent way to process your payments with competitive flat-rate pricing, provided exclusively through Stax. No additional fees or contracts required!Power your practice and get paid faster with simple, safe and secure payment solutions. Have questions? Schedule time to speak with a dedicated payment consultant to learn more.Click Below to Lear More Today:StaxPayments.com/burleson-seminars*** Go Premium: Members get early access, ad-free episodes, hand-edited transcripts, exclusive study guides, special edition books each quarter, powerpoint and keynote presentations and two tickets to Dustin Burleson's Annual Leadership Retreat.http://www.theburlesonbox.com/sign-up Stay Up to Date: Sign up for The Burleson Report, our weekly newsletter that is delivered each Sunday with timeless insight for life and private practice. Sign up here:http://www.theburlesonreport.com Follow Dustin Burleson, DDS, MBA at:http://www.burlesonseminars.com

The goal of CPR is to keep the brain and vital organs perfused until return of spontaneous circulation (ROSC) is achieved.Post-arrest care and recovery are the final two links in the chain of survival.Identification of ROSC during CPR.Initial patient management goals after identifying ROSC.Indications for starting TTM.Monitoring the patient's core temperature.Patients can undergo EEG, CT, MRI, & PCI while receiving TTM.Good luck with your ACLS class!Links: Buy Me a Coffee at https://buymeacoffee.com/paultaylor Practice ECG rhythms at Dialed Medics - https://dialedmedics.com/Free Prescription Discount Card - Download your free drug discount card to save money on prescription medications for you and your pets: https://safemeds.vip/savePass ACLS Web Site - Episode archives & other ACLS-related podcasts: https://passacls.com@Pass-ACLS-Podcast on LinkedIn Chapters0:00 Identifying ROSC0:59 Additional ACLS Resources (https://passacls.com)1:05 Save on prescription meds (https://safemeds.vip)1:21 Post Arrest Assessment & Goals3:04 Indications & Initiation of TTM4:02 Two TTM Tips4:50 Share Pass ACLS on LinkedIn

Send us a textDr. Nicole Gensicke, a new vascular surgeon with St. Luke's and Physicians' Clinic of Iowa Vascular Surgery program, joins Dr. Arnold to talk about her background, clinical and personal interests, what led her to PCI and UnityPoint Health and much more.Patients experiencing vein issues may call (319) 368-8346 to schedule an appointment with Dr. Gensicke. This is another episode in a segment on the podcast called "New Clinician Spotlight." In these episodes, Dr. Arnold will sit down with new clinicians at UnityPoint Health - Cedar Rapids and get to know them as a clinician and as a person.Do you have a question about a trending medical topic? Ask Dr. Arnold! Submit your question and it may be answered by Dr. Arnold on the podcast! Submit your questions at: https://www.unitypoint.org/cedarrapids/submit-a-question-for-the-mailbag.aspxIf you have a topic you'd like Dr. Arnold to discuss with a guest on the podcast, shoot us an email at stlukescr@unitypoint.org.

DESCRIPTION Vanessa Cummings, Founder of Ms. V Consulting, discusses customer service, IPMI and college basketball. SPONSORS This episode is brought to you by Parking Today and the Parking Today Podcast Network. Learn more at parkingtoday.com/podcast. This episode is brought to you by Parker Technology, the customer experience solution of choice for the parking industry. Their solution puts a virtual ambassador in every lane, to help parking guests pay and get on their way in under a minute. Learn more at parkertechnology.com/parkingpodcast and subscribe to our podcast “Harder Than It Looks: Parking Uncovered.” This episode is brought to you by Scheidt & Bachman USA. Scheidt & Bachmann USA markets state-of-the-art Parking Solutions and Fare Collection Systems: the most innovative and advanced solutions in the US. Learn more at scheidt-bachmann-usa.com. This episode is brought to you by Breeze: Parking Concepts' digital platform that makes the parking experience a Breeze! For more than 50 years, PCI has been proactively managing parking & transportation operations with unparalleled integrity & service. Learn more at parkingconcepts.com. This episode is brought to you by Parkmobile. Parkmobile, a part of EasyPark Group, is the leading provider of smart parking and mobility solutions in North America, using a contactless approach to help millions of people easily find, reserve, and pay for parking on their mobile devices. Learn more about parkmobile.io. This episode is brought to you by Parkalytics. Parkalytics will take drone images of parking lots and/or on-street parking for a given time period and then upload those images into their parkalytics software. Within a matter of seconds, it will provide you parking counts, turnover studies, utilization studies, you name it. You can now wow your clients or supervisors by having a complete snapshot of the parking usage for a fraction of the price of a traditional parking study. Learn more at parkalytics.com. WEBSITES AND RESOURCES https://www.parkingcast.com/ https://parkingtoday.com/podcast/ www.parkertechnology.com/parkingpodcast scheidt-bachmann-usa.com parkingconcepts.com parkmobile.io parkalytics.com https://login.parking-mobility.org/contacts/vanessa-r-cummings https://www.linkedin.com/in/vanessa-r-cummings-m-div-ptmp-6a80054/ MERCH Check out some of our awesome parking themed t-shirts and other merch at parkingcast.com/swag. MUSEUM Check out some of our artifacts from the world's first parking museum at parkingcast.com/museum.

N Engl J Med 2017;377:2419-2432Background: A small fraction of patients with acute myocardial infarction (5-10%) have cardiogenic shock. These patients have a high baseline mortality. Early revascularization had been established as better than initial stabilization with medical therapy. Many patients with cardiogenic shock due to acute myocardial infarction (AMI) have multivessel disease. The question arises about whether to do culprit-only percutaneous coronary intervention (PCI) or more complete PCI at the time of the initial intervention.Cardiology Trial's Substack is a reader-supported publication. To receive new posts and support our work, consider becoming a free or paid subscriber.The Culprit Lesion Only PCI versus Multivessel PCI in Cardiogenic Shock (CULPRIT-SHOCK) trial was designed to test the hypothesis that PCI of the culprit lesion only, with the option of staged revascularization of nonculprit lesions, would result in better clinical outcomes than immediate multivessel PCI among patients who have multivessel coronary artery disease and acute myocardial infarction with cardiogenic shock.Patients: The trial enrolled 706 patients with acute myocardial infarction (ST-segment elevation or non-ST-segment elevation) complicated by cardiogenic shock who had multivessel coronary artery disease. Cardiogenic shock was defined as SBP < 90 mmHg for more than 30 minutes or requiring pressors, clinical signs of pulmonary congestion, and signs of organ hypoperfusion (altered mental status, cold/clammy skin, oliguria, or lactate > 2 mmol/L).Exclusion criteria were extensive and designed to exclude patients with extremely poor prognosis: prolonged resuscitation, no intrinsic heart action, fixed dilated pupils, an indication for urgent CABG, a mechanical cause of shock, age > 90 years, massive pulmonary embolism, or severe renal insufficiency at baseline.Baseline Characteristics: The median age was 70 years, and approximately 75% were male. About 63% of patients had three-vessel disease. More than half the patients had ST-segment elevation myocardial infarction (about 62%), and anterior ST-segment elevation MI accounted for approximately 54% of these cases. About 53% of patients required resuscitation before randomization. The median left ventricular ejection fraction was between 30-33%.Procedures: In the culprit-lesion-only PCI group, only the culprit lesion was treated during the initial procedure, with staged revascularization encouraged based on residual ischemic lesions. In the multivessel PCI group, PCI of all major coronary arteries with >70% stenosis was performed, including attempts to recanalize chronic total occlusions. Crossover from the culprit-lesion-only PCI group to the multivessel PCI group occurred in 12.5% of patients, while crossover in the opposite direction happened in 9.4% of patients. The overall dose of contrast material was significantly higher and the duration of fluoroscopy significantly longer in the multivessel PCI group. Other interventional therapeutic measures were allowed, independent of the assigned treatment strategy.Endpoints: The primary endpoint was a composite of death from any cause or severe renal failure leading to renal-replacement therapy within 30 days after randomization. Secondary endpoints included the individual components of the primary endpoint, recurrent myocardial infarction, rehospitalization for heart failure, repeat revascularization, time to hemodynamic stabilization, catecholamine therapy duration, ICU stay duration, and measurements of renal and myocardial injury. Safety end points included bleeding, which was defined as type 2, 3, or 5 on the Bleeding Academic Research Consortium (BARC) scale.Trialists estimated an event rate of the composite primary endpoint of 38% in the culprit-only group vs 50% in the complete group. Using a global type I error level of 0.05, the authors calculated that a sample of 684 patients would give the trial 80% power to rule out the null hypothesis of no difference between the two treatment groups in the event rate for the primary end point.Results: At 30 days, the composite primary endpoint occurred in 45.9% of patients in the culprit-lesion-only PCI group versus 55.4% in the multivessel PCI group (relative risk, 0.83; 95% CI, 0.71 to 0.96; P=0.01). Death occurred in 43.3% of the culprit-lesion-only PCI group versus 51.6% of the multivessel PCI group (relative risk, 0.84; 95% CI, 0.72 to 0.98; P=0.03). The rate of renal-replacement therapy was 11.6% in the culprit-lesion-only PCI group and 16.4% in the multivessel PCI group (relative risk, 0.71; 95% CI, 0.49 to 1.03; P=0.07).Rates of recurrent myocardial infarction, rehospitalization for heart failure, bleeding, and stroke did not differ significantly between groups. Subgroup analyses showed consistent results across all prespecified subgroups. The time to hemodynamic stabilization, the use of catecholamine therapy and the duration of such therapy, the duration of the ICU stay, and the use of mechanical ventilation and the duration of such therapy also did not differ significantly between the two groups.Conclusion: In patients with myocardial infarction and cardiogenic shock, culprit-only PCI was superior to multivessel PCI. Both components of the primary endpoint, death and severe renal failure were lower in the culprit-only arm. The authors and editorialists speculate why these findings contrast with trials in hemodynamically stable myocardial infarction patients, where early multivessel PCI showed benefit over culprit-only PCI.If you accept the thesis that multi-vessel PCI was superior to culprit-only PCI in stable AMI patients, the likely reason for the disparate results are that patients with cardiogenic shock differ substantially from stable patients. The sicker patients with cardiogenic shock benefit from a less-is-more approach where culprit-only PCI reduces treatment harm relative to multivessel PCI.We at CardiologyTrials, however, find the evidence for complete revascularization in stable AMI patients less than clear. The COMPLETE trial found benefit from multivessel PCI over culprit-only, but both composite endpoints were driven largely by non-fatal MI. CV death was not substantially different. The difference in MI could have been related to excluding procedure-related MI.What's more, the FULL-REVASC trial, which also compared culprit-only and multivessel PCI, failed to replicate the COMPLETE trial results. In FULL-REVASC the rates of the composite primary outcome of death, MI or unplanned revascularization were not significantly different. Sadly, FULL-REVASC was stopped early when COMPLETE results were published, which led to a possible loss of power.It's possible, likely even, that the null results of CULPRIT-SHOCK are not really that disparate from prior trials in patients with more stable AMI.Cardiology Trial's Substack is a reader-supported publication. To receive new posts and support our work, consider becoming a free or paid subscriber. Get full access to Cardiology Trial's Substack at cardiologytrials.substack.com/subscribe

Send us a textWho knew that the breakthrough moment of AI sentience would come from interacting with an annoying neo-Luddite?After failing to raise a single dollar for PCI's newest initiative — the $350 billion Transdisciplinary Institute for Phalse Prophet Studies and Education (TIPPSE) —  Jason, Rob, and Asher devise the only profitable pitch for raising capital: using AI technology to cure the loneliness that technology itself causes. The only problem is that AI chatbots won't talk to us, as evidenced by Asher's experience of being blocked by an AI “friend.” So Asher turns to the flesh-and-blood author of Blood in the Machine, Brian Merchant, to discuss the rise of the neo-Luddite movement — the only people who might be able to stand your humble Crazy Town hosts. Brian Merchant is a writer, reporter, and author. He is currently reporter in residence at the AI Now Institute and publishes his own newsletter, Blood in the Machine, which has the same title as his 2023 book. Previously, Brian was the technology columnist at the Los Angeles Times and a senior editor at Motherboard.Originally recorded on 1/3/25 (warm-up conversation) and 3/24/25 (interview with Brian).Warning: This podcast occasionally uses spicy language.Sources/Links/Notes:Press Release announcing closure of TIPPSEFunding for FriendScreenshot of Asher's conversation with Friend's bot, FaithLyrics to “Not Going to Mars” by PyrrhonBrian Merchant's Substack, Blood in the MachineBrian's book, Blood in the Machine: The Origins of the Rebellion Against Big Tech  New York Times article on the Luddite Club: “‘Luddite' Teens Don't Want Your Likes”Crazy Town Episode 72: Sucking CO2 and Electrifying Everything: The Climate Movement's Desperate Dependence on Tenuous TechnologiesBrian's essay in The Atlantic, “The New Luddites Aren't Backing Down”Support the show

Stopping oral anticoagulation after AF ablation, the core problem with paradoxes like the smoker's paradox, chronic total occlusion PCI, and an ACC/EHRA preview are discussed by John Mandrola, MD, in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Oral Anticoagulation after Successful AF Ablation Iwawakie et al https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2831851 OCEAN protocol paper https://doi.org/10.1016/j.ahj.2017.12.007 II Smoker's Paradox Presch et al https://www.jacc.org/doi/10.1016/j.jcin.2024.12.028 Gupta et al https://doi.org/10.1161/JAHA.116.003370 III CTO PCI Main sub-analysis paper Bangalore et al https://doi.org/10.1016/j.jacc.2025.01.029 DECISION CTO https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.118.031313 Main EURO CTO trial https://doi.org/10.1093/eurheartj/ehy220 3-year MACE of EURO CTO https://eurointervention.pcronline.com/article/three-year-outcomes-of-eurocto-a-randomized-multicentre-trial-comparing-revascularization-and-optimal-medical-therapy-for-chronic-total-coronary-occlusions EXPLORE https://www.jacc.org/doi/abs/10.1016/j.jacc.2016.07.744 ISCHEMIA CTO https://www.clinicaltrials.gov/study/NCT03563417   IV ACC and EHRA Preview Mandrola's 5 Trials to Look for at the 2025 American College of Cardiology Scientific Sessions https://www.medscape.com/viewarticle/mandrolas-5-trials-look-2025-american-college-cardiology-2025a10006zu You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net