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Listener feedback on valvular heart disease, statins and frailty, left atrial posterior wall ablation fails again, interpreting medical tests and AI ECG reading are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Listener Feedback PREVUE-VALVE Study https://www.jacc.org/doi/10.1016/j.jacc.2026.02.5137 II Statins and Frailty Statin Initiation Tied to Lower Frailty Risk in Older Adults https://www.medscape.com/viewarticle/statin-initiation-tied-lower-frailty-risk-older-adults-2026a1000lec Statins and Survival Free of Incident Frailty https://doi.org/10.1093/eurheartj/ehag451 III LA Posterior Wall Isolation Fails Again CORNERSTONE Trial https://doi.org/10.1093/eurheartj/ehag486 CAPLA Trial https://jamanetwork.com/journals/jama/fullarticle/2800186 IV Does the Display of Test Results Improve Clinical Decisions? Interval Likelihood Ratios for Clinical Decsion-Making https://evidence.nejm.org/doi/full/10.1056/EVIDoa2500249 Making Sense of Health Statistics https://journals.sagepub.com/doi/full/10.1111/j.1539-6053.2008.00033.x V AI and the ECG and Saving Doctors Case Report — AI-Enhanced Diagnostics https://www.nature.com/articles/s41591-026-04454-y The New York Times article https://www.nytimes.com/2026/06/22/health/artificial-intelligence-heart-damage.html You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net
This episode is part of our comprehensive Decipher the Guidelines Series covering the 2025 ACC/AHA/ACEP/NAEMSP/SCAI Guideline for the Management of Patients With Acute Coronary Syndromes. The following question refers to Section 5.2.1 of the 2025 ACS Guidelines. The question is asked by Thomas Jefferson medical student and CardioNerds Academy Intern Dr. Grace Qiu, answered first by Henry Ford Interventional cardiology fellow and member of the CardioNerds Interventional Cardiology Council Dr. Li Pang, and then by expert faculty Dr. Michelle O'Donoghue. Dr. O'Donoghue is a cardiologist, senior investigator with the TIMI Study Group, and Associate Professor of Medicine at Harvard Medical School who holds the McGillycuddy-Logue Endowed Chair in Cardiology at Brigham and Women's Hospital. She was the Vice Chair of the Writing Committee for the 2025 ACS Guidelines. Question #2 A 63-year-old woman presented to the emergency room for chest pain. She described having exertional chest pain for the past two months and had an episode of severe pain after dinner 3 days ago. She went to bed and slept it off. She told her children today at a family gathering, and was immediately brought to the ED by her daughter. She has a history of hypertension and hyperlipidemia. She was asymptomatic and normotensive in the ED. Labs show a down-trending troponin and an elevated NT-proBNP but are otherwise unremarkable. Her ECG showed Q waves with ST elevation in V2-V4. She was treated with aspirin and heparin drip, and taken to the cath lab. Coronary angiogram showed complete proximal LAD occlusion with right-to-left collaterals, without significant residual disease elsewhere. She remains asymptomatic and is stable, both hemodynamically and electrically. What is the next best step with regard to reperfusion and anti-thrombotic management? A Proceed with primary PCI to LAD B Medical management with aspirin and enoxaparin C Medical management with aspirin and clopidogrel D Medical management with aspirin and ticagrelor Answer #2 Explanation The Correct answer is D In patients who are stable with STEMI and have a totally occluded infarct-related artery >24 hours after symptom onset and are without evidence of ongoing ischemia, acute severe HF, or life-threatening arrhythmia, PPCI should not be performed due to lack of benefit. (Class 3, LOE B-R) The benefit of PPCI begins to diminish after >12 hours from symptom onset, but there appears to be continued benefit through approximately 24 hours. In stable asymptomatic patients with an occluded artery >48 hours after symptom onset, routine PCI has not been shown to be beneficial in the absence of ongoing ischemia. The relative utility of routine PCI for asymptomatic patients with STEMI between 24 and 48 hours from symptom onset is less rigorously tested. PCI is not recommended for an occluded infarct-related artery if the patient is asymptomatic and has a completed infarct. MACE outcomes were similar in those with an occluded infarct-related artery who underwent medical therapy versus those who underwent PCI 3 to 28 days after an MI (Occluded Artery Trial [OAT]), and results were no different at 7-year follow-up. Similar findings were noted in the DECOPI (Desobstruction Coronaire en Post-Infarctus) trial, which enrolled patients with an occluded artery and Q waves on the ECG presenting 2 to 15 days after symptom onset. However, coronary revascularization should be considered for patients with late presentations with continued signs and symptoms of ischemia, including cardiogenic shock, acute severe HF, persistent angina, and life-threatening arrhythmias. Main Takeaway In patients who are stable with STEMI who have a totally occluded infarct-related artery >24 hours after symptom onset and are without evidence of ongoing ischemia, acute severe HF, or life-threatening arrhythmia, PPCI should not be performed due to lack of benefit. Guideline Loc. Section 5.2.1
What We CoveredWhat if your wearable could do more than track steps — and actually help detect cardiovascular risk before symptoms appear?In this episode, Joe talks with University of Pittsburgh's Pengfei Zhou & Matt de Lima Barbosa, along with Dell Technologies' Adrienne Garber, about how AI, edge computing, and wearable devices are shaping the future of heart monitoring.01 Why wearables are the next frontier for heart health: how real-time sensor data from everyday devices could detect cardiovascular risk before symptoms ever appear.02 What AIoT actually means in practice: how Pengfei's research combines AI and connected sensors to build deep learning models that go far beyond step counting.03The role of embedded IT in research speed: how Matt's team connects faculty to secure infrastructure and technical support so researchers can move faster and focus on the science.04 How Dell is partnering with higher ed researchers: why Adrienne's team invests in university innovation programs — and what that looks like when it reaches researchers working on real health problems.05 Why localized AI wins on speed, privacy, and personalization: the case for keeping AI processing at the edge instead of sending sensitive health data to the cloud.06 What the future of higher ed innovation actually requires: why the collaboration between researchers, IT, and technology partners like Dell is the ingredient most people overlook. FeaturingPengfei Zhou, Assistant Professor, University of Pittsburgh School of Computing and InformationMatt de Lima Barbosa, Director of Information Technology, University of Pittsburgh School of Computing and InformationAdrienne Garber, Chief Technology & Innovation Strategist, Higher Ed, Dell Technologies Timestamps(01:00) Inside Pitt's School of Computing and Information(02:45) Pengfei Zhou's teaching and research focus(03:53) AIoT, wearables, and heart monitoring(07:04) How Dell's higher ed innovation pilot reached Pitt(10:41) Why localized AI matters for health data(12:18) How embedded IT helps researchers move faster(13:41) Dell's role as connective tissue between researchers and IT(18:18) Combining PPG and ECG signals for better blood pressure monitoring(21:00) The “Who Not How” Moment: Helping researchers move faster(25:12) AI, deep learning, and solving real problemsListen now: YouTube x Apple x SpotifyWhenever you're ready, there are 3 ways you can connect with TechTables:1.
CardioNerds (Amit and Dan), Billy Joe Mullinax, and Saahil Jumkhawala discuss the long term management of pulmonary embolism with Dr. Soophia Naydenov. The episode focuses on the approach to patients who struggle with persistent symptoms like dyspnea and fatigue even after completing the acute phase of anticoagulation. This spectrum of disease, ranging from mild post-PE impairment to chronic thromboembolic pulmonary hypertension (CTEPH), requires a structured follow-up. The discussion covers the critical importance of identifying CTEPH early, the necessary timelines for follow-up, and the appropriate objective screening tools and invasive testing to guide patient care toward full functional recovery. Audio editing by CardioNerds academy intern, Grace Qiu. Dr. Dinu Balanescu and Dr. Billy-Joe Mullinax are Co-chairs for the CardioNerds PE Series, developed in collaboration with the PERT Consortium. Enjoy this Circulation 2022 Paths to Discovery article to learn about the CardioNerds story, mission, and values. CardioNerds Pulmonary Embolism PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Acronyms PE: Pulmonary Embolism PERT: Pulmonary Embolism Response Team CTEPH: Chronic Thromboembolic Pulmonary Hypertension QL: Quality of Life VTE: Venous Thromboembolism DASH: D-dimer, Age, Sex, History of non-provoked PE (a risk score) CPET: Cardiopulmonary Exercise Testing PFTs: Pulmonary Function Tests VQ Scan: Ventilation-Perfusion Scan DOACs: Direct Oral Anticoagulants TPA: Tissue Plasminogen Activator (Thrombolytics) ECMO: Extracorporeal Membrane Oxygenation Pearls: Post-PE “Syndrome” is a Spectrum: It is more accurately a spectrum of disease (sequelae of PE) rather than a single syndrome, ranging from mild fatigue/dyspnea to the most severe form, CTEPH. Structured Follow-up is Mandatory: All PE survivors need a structured follow-up, typically with checkpoints at 3, 6, 12, and 16–24 months, with the primary goal being to detect CTEPH, the deadliest, yet potentially curable, disease on the spectrum. Screening Should Be Objective and Practical: When screening for persistent symptoms, use objective assessment tools like the Post-VTE Functional Status (PVFS) scale or the Modified Medical Research Council (MMR-C) scale, as highly comprehensive but cumbersome tools (like the PE Quality of Life questionnaire) may not be practical for routine clinical use. Recurrence Risk Scores Aid in Anticoagulation Duration: Simple scores like the DASH score or the HERDO2 score (for women) can provide guidance when considering the continuation versus discontinuation of anticoagulation after the initial treatment phase. Invasive Testing for Persistent Symptoms: If a patient remains symptomatic at the 6-month mark despite normal non-invasive testing (chest X-ray, ECG, PFTs, six-minute walk, echo, VQ scan, CPET), consider invasive testing such as Right Heart Catheterization (RHC) at rest or with exercise, or an invasive CPET. Notes: Notes drafted by Saahil Jumkhawala. 1. The Spectrum of Post-PE Disease The term “post-PE syndrome” should be used with caution, as it refers to a spectrum of disease rather than a single entity. This spectrum includes symptoms (sequelae) that exist in a patient’s life following an incidental PE event that they did not have before. On one extreme is Chronic Thromboembolic Pulmonary Hypertension (CTEPH): The definition is clear, but it is the most deadly type, though thankfully rare (2% to 4%). It involves a residual clot and pulmonary hypertension identifiable at rest. In the middle is Chronic Thromboembolic Disease (CTED): Patients may have residual defects seen on a VQ or CT scan, but they do not have pulmonary hypertension. On the other side is a milder disease, which can include fatigue, dyspnea, or a patient’s perceived impairment, where the definitions of CTEPH and CTED are not met, but the patient remains symptomatic. 2. Structured Follow-up and Screening for Post-PE Symptoms Structured follow-up is key for all PE survivors, though the structure may vary based on available resources (PCP, Cardiology, Pulmonary, or multidisciplinary clinic). Recommended Timeline for Follow-up: Data from studies like ELOPE and FOCUS suggest checkpoints at 3, 6, 12, and up to 16 to 24 months. This timeline is designed to identify patients who may develop CTEPH. 88% of patients who develop CTEPH will be identified within about a year. A structured follow-up can reduce the delay in CTEPH diagnosis from 10–12 months to 4–6 months. Personal Practice Note: A quick 2–3 week/30-day check-in is recommended for severely ill patients (e.g., those who had TPA, profound shock, or ECMO support) to ensure medication compliance, manage symptoms, and identify red flags. Screening Tools (Objective Assessment): The first step is an inventory of patient symptoms, leaning toward objective rather than subjective assessment. Recommended Simple Tools: Modified Medical Research Council (MMR-C) for dyspnea evaluation. Post-VTE Functional Status (PVFS) scale. The Pulmonary Embolism Quality of Life (QL) questionnaire is comprehensive but long, making it tedious and better suited for research. Future Utility: Technology (AI/electronic tools) may assist in administering these questionnaires before the clinic visit, presenting the information as a “dashboard” for the provider. 3. Management of Persistent Symptoms and Further Testing Initial Non-Invasive Tests (Often done at 3 months): Echocardiogram VQ Scan Full PFTs Six-minute walk CPET Further Evaluation for Persistent Symptoms (e.g., at 6 months): If non-invasive tests (Chest X-ray, ECG, CPET) are normal but symptoms persist, more invasive testing should be considered as the patient has not returned to baseline. Repeat VQ scan or echocardiogram if symptoms have changed. Right Heart Catheterization (RHC) at rest or with exercise. Invasive CPET. PA gram (Pulmonary Angiogram) to assess vasculature. 4. Recurrence Risk and Anticoagulation Duration The decision to continue or discontinue anticoagulation depends on the patient’s risk factors, the situation of the PE (provoked or unprovoked), presence of active cancer, and patient preference. Recurrence Risk Scores: Simple scores are preferred for practicality. DASH Score. HERDO2 Score (particularly for women). The Vienna Score can be considered if the question is whether to restart anticoagulation after a disruption. Role of D-dimer in Abbreviation: While D-dimer can be used to guide the decision to restart anticoagulation after a planned pause (if D-dimer is high, resume), patient symptoms are preferable to guide management decisions like early abbreviation. 5. Prevention of Post-PE Syndrome Currently, there is no clear tool known to prevent the post-PE syndrome/spectrum of disease. Best Current Advice for Prevention/Recovery: Anticoagulation compliance. Pulmonary rehabilitation, which aids in faster recovery. General precautions, such as smoking cessation and body weight management. Future Research: Ongoing trials are investigating whether acute management strategies (e.g., using thrombolytics in intermediate-risk PE) can prevent long-term sequelae. (The PYTHO trial did not show a reduced rate of CTEPH in intermediate-risk PE patients who received thrombolytics). References: Khan, F., Tritschler, T., Kahn, S. R., & Rodger, M. A. “Venous Thromboembolism.” The Lancet, vol. 398, no. 10294, 2021, pp. 64-77. doi:10.1016/S0140-6736(20)32658-1. Kearon, C., & Kahn, S. R. “Long-Term Treatment of Venous Thromboembolism.” Blood, vol. 135, no. 5, 2020, pp. 317-325. doi:10.1182/blood.2019002364. Kahn, S. R., & de Wit, K. “Pulmonary Embolism.” The New England Journal of Medicine, vol. 387, no. 1, 2022, pp. 45-57. doi:10.1056/NEJMcp2116489. Di Nisio, M., van Es, N., & Büller, H. R. “Deep Vein Thrombosis and Pulmonary Embolism.” The Lancet, vol. 388, no. 10063, 2016, pp. 3060-3073. doi:10.1016/S0140-6736(16)30514-1. Chopard, R., Albertsen, I. E., & Piazza, G. “Diagnosis and Treatment of Lower Extremity Venous Thromboembolism: A Review.” JAMA, vol. 324, no. 17, 2020, pp. 1765-1776. doi:10.1001/jama.2020.17272.
On today's bonus episode of ECG, Pugs hopes to strike it big with Yu-Gi-Oh cards, and Ellie brings out the best gaming WYR question of all time. Hosted on Acast. See acast.com/privacy for more information.
In this episode, host Steve Prentice talks with Ant Allan, former VP Analyst at Gartner, to explore a future where identity is no longer a single moment at login, but a continuous, evolving signal. As AI agents begin acting on our behalf, and deepfakes challenge the very idea of “proof,” traditional authentication models are breaking down. Ant explains why biometrics, from device‑bound fingerprints to vein patterns and continuous ECG, are becoming essential evidence in the identity equation. He also reveals why friction still matters: not as an inconvenience, but as a psychological anchor that reassures users during high‑risk actions. If you want to understand where authentication is truly headed - beyond passwords, beyond factors, and into a world where trust never sleeps, this conversation is essential listening.
On this week's episode of ECG, Ellie buys some badges, Chris updates everyone on the bleed nipple issue and special guest James Pugsley shares a spine-tingling Bloodborne speech. Hosted on Acast. See acast.com/privacy for more information.
Rapido, sicuro e non invasivo, l'elettrocardiogramma (ECG) è uno degli esami più utilizzati per valutare la salute del cuore. Ma come funziona e quali informazioni può fornire? In questa puntata di “Un esame visto da vicino”, insieme al prof. Claudio Borghi, Professore di Medicina Interna all’Università di Bologna, scopriamo il valore diagnostico dell'ECG, il suo ruolo nella prevenzione cardiovascolare e le principali situazioni in cui viene prescritto.
Tim Mages is the CEO of ECG, expansion capital group, where he helps businesses secure customized financing solutions to support growth, operations, and long-term success. With extensive experience in commercial finance and equipment leasing, Tim works closely with companies across a variety of industries to structure funding solutions tailored to their specific needs. Under his leadership, ECG has built a strong reputation for providing flexible financing options and helping businesses navigate complex funding challenges efficiently. Tim brings a practical and relationship-driven perspective to business lending, capital access, and strategic financing. Tim's perspective would be especially valuable for conversations around commercial finance, equipment leasing, business growth strategies, and how companies can better position themselves to access capital in today's market. During the show we discuss: Why traditional banks reject so many small business owners (and what they're really looking for) How alternative lenders evaluate risk differently—and why that opens more doors The biggest mistakes entrepreneurs make when trying to secure funding How to position your business to get approved faster and for higher amounts Why speed and flexibility in funding can be a competitive advantage The truth about merchant cash advances, equipment financing, and other options—what's legit and what's misunderstood How lenders think about cash flow vs. credit scores What it really takes to scale using capital without putting your business at risk Resources: Website: https://www.ecg.com/ LinkedIn: https://www.linkedin.com/in/tim-m-1647775/
11 years ago I gave a TEDx talk that has now had nearly 9 million views. I haven't watched it back in years, so today I'm rewatching it live, sharing what still resonates, and telling you the parts I never spoke about on that stage. WE'LL TALK ABOUT... The live experiment I opened the talk with, and the man in the audience whose reason for volunteering stopped me in my tracks. Why what's going on in your head has more impact on your results than almost anything else. The period of my life where I went from optimistic go-getter to completely self-sabotaging, and what that actually felt like. The heart palpitations, the ECG machine, and what my body was trying to tell me before I finally listened. Why I packed my bags and flew to Australia looking for an epiphany. The E-Myth funeral exercise that changed everything for me. How I programmed my mind for success, and why I still use these exact tools today. I also share the things that didn't make it into the talk. Honestly, watching this back, I want to hug that version of myself for being brave enough to get up there. Because the biggest thing standing between you and where you want to be is almost always you. And the moment you have awareness on that, everything can shift. Let me know in the comments what landed most for you. Carrie xx
In this episode of Value Based Care Insights, host Daniel Marino is joined by ECG's Amanda Adams and Jessica Wells to discuss key themes and takeaways from the Becker's Healthcare 16th Annual Meeting in Chicago. Together, they explore how healthcare organizations are rethinking workforce development, physician leadership, and operational integration amid growing financial, regulatory, and staffing pressures.The conversation highlights the evolving role of academic health systems, the need to break down silos across clinical, research, and educational missions, and the importance of preparing a workforce ready for the future of care delivery. They also discuss leadership development, rural health challenges, artificial intelligence's growing influence on workforce strategy, and how healthcare provider organizations can create more sustainable, integrated care environments while improving engagement and performance across teams. Connect with AmandaConnect with Jessica
On this episode host Dan Marino is joined by ECG's Amanda Adams and Jessica Wells to discuss key themes and takeaways from the Becker's Healthcare 16th Annual Meeting in Chicago. Together, they explore how healthcare organizations are rethinking workforce development, physician leadership, and operational integration amid growing financial, regulatory, and staffing pressures. The conversation highlights the evolving role of academic health systems, the need to break down silos across clinical, research, and educational missions, and the importance of preparing a workforce ready for the future of care delivery. They also discuss leadership development, rural health challenges, artificial intelligence's growing influence on workforce strategy, and how healthcare provider organizations can create more sustainable, integrated care environments while improving engagement and performance across teams. To stream our Station live 24/7 visit www.HealthcareNOWRadio.com or ask your Smart Device to “….Play Healthcare NOW Radio”. Find all of our network podcasts on your favorite podcast platforms and be sure to subscribe and like us. Learn more at www.healthcarenowradio.com/listen
On today's bonus episode of ECG, the team discuss the real life possibility of post-launch software updates, and which updates they'd love for their own personal lives. Hosted on Acast. See acast.com/privacy for more information.
My cardiologist ran a full cardiac workup (MRI, stress test, ambulatory ECG, labs) and told me I was perfectly healthy. I was 40 lbs overweight, insulin-resistant, nutritionally deficient, and running on 2–4 hours of sleep. Everything was "normal." Nothing was fine. ▶ FREE email course: the exact steps I used to go from dysfunction toward resilient health (no cost, straight to your inbox): https://medgeeks.co/get-started/metabolic-health/ If you're a clinician, this one's for you. You read labs all day, but nobody is reading yours. And "normal" labs can hide a metabolism that's quietly drifting years before any diagnosis shows up. In this video, I break down the gap between what your bloodwork flags and what your body is actually doing; why conventional medicine is built to catch disease but not dysfunction, why the reference range fails you, and what it actually takes to move toward what I call resilient health. We cover insulin resistance, the reference range problem, cellular metabolism, an autoimmune marker (ANA) that turned negative once I fixed the underlying environment, and the full spectrum from dysfunction to disease-free to resilient health.
On this weeks episode of ECG, Chris revives the golden age of kiwi TV, Guy commits murder on a beloved New Zealand animal, and Ellie throws her back out picking up a sock. Hosted on Acast. See acast.com/privacy for more information.
Why are young Indians dying of cardiac arrest? Why are fit, healthy people in their 30s and 40s suddenly collapsing at the gym, at weddings, on stage, in their sleep — with no warning?In this episode of xMonks Drive, host Gaurav Arora sits down with Dr. Avinash Verma, Director of Cardiac Electrophysiology and Pacing at BLK-Max Super Speciality Hospital, New Delhi, for one of the most important conversations about heart health in India.Dr. Avinash Verma is one of India's leading cardiac electrophysiologists with over 15 years of experience, 2,400+ device implantations, and 1,300+ radiofrequency ablations. He is the only doctor in North India trained in laser-assisted lead extraction. In this episode, he explains why Indians get heart disease 10 years earlier than Western populations, what the difference is between a heart attack and a cardiac arrest, and why India's out-of-hospital cardiac arrest survival rate is just 2-3% compared to 50-60% in the world's best out-of-hospital cardiac arrest programs.Dr. Verma shares real patient stories including a 36-year-old woman who passed away from sudden cardiac death after refusing a life-saving device, a cardiology colleague who collapsed outside his own home just 1 kilometre from the hospital and could not be revived, and a 19-year-old whose brother had passed away at 17 from a genetic heart condition — who is now thriving after treatment. He also discusses the cases of Sidharth Shukla, Shefali Jariwala, KK, and Prateek Yadav, and explains what actually happens during these sudden cardiac events.Topics covered in this episode include sudden cardiac death in young Indians, hypertrophic cardiomyopathy, inherited heart conditions, genetic screening for heart disease, cardiac arrest vs heart attack, how CPR works and why it must be taught in Indian schools, pacemakers and ICDs, the danger of steroids and unregulated gym supplements, why vaping is illegal in India and what it does to the heart, why sugar may be as harmful as smoking, the link between sleep deprivation and heart disease, chronic stress and the heart's electrical system, sedentary lifestyle and cardiac risk, binge drinking and arrhythmia, the role of COVID and vaccines in myocarditis, the truth about pharma conspiracy theories, Ayurveda and evidence-based medicine, whether smartwatch ECG data is medically reliable, the genetic risk of same-community marriage, organ donation and heart transplant in India, and why selling miracle cures is illegal in India.If you or someone you love has a family history of cardiac arrest, heart disease, or sudden unexplained loss — this episode could save a life. Dr. Verma explains exactly what tests to get, what warning signs to watch for, and what to do if someone collapses near you.
The Advantage of Rapid Prototyping in Wearable MedTech DevelopmentModern cancer treatments are getting better at targeting specific forms of cancer. However, this improved effectiveness often introduces lethal side effects. Skribe Medical is developing wearable technologies to help oncologists monitor and manage these side effects and ultimately improve cancer survivability.In Episode 45 of the MedTech Speed to Data podcast, Key Tech's Andy Rogers has a conversation with Ryan Neely, Skribe Medical's CEO and co-founder, about the startup's approach to rapid prototyping, clinical trials, and wearable technology.Need to knowCancer treatment can be lethal — The most effective drugs often come with black box warnings of harmful and lethal side effects.600,000 US patients are at risk of cardiotoxicity — Toxic drugs damage the heart, leading to complications like arrhythmia and heart failure.Managing cardiotoxicity can delay cancer treatments — Oncologists must now schedule patients for third-party ECG testing, which takes time and delays treatment.The nitty-grittySkribe Medical is developing a wearable ultrasound sensor that detects cardiotoxicity signals for use in oncology clinics. “We have a patch that can be worn to detect cardiotoxicity and really streamline monitoring of heart health,” Neely says. “Rather than an oncologist sending a patient to get a cardiac ultrasound, which could take weeks, the patch can just be placed above the heart for about five minutes. We record a bunch of different signals, pass them through an AI model, and then we can give them either a thumbs up or a thumbs down.”Neely goes on to explain how the in-clinic wearable approach delivers benefits beyond better patient outcomes. “The first device that we're building is intended to be used in the clinic by a nurse or a medical assistant. By the time the doctor is there, you've got your answer.”Designing a wearable device rather than an implant created several advantages for Skribe Medical during its early development. “In a regulated industry like medical devices,” Neely explains, “it's like a little bit of a chicken and egg where people say, ‘we'd like to see some clinical validation' and you're thinking, ‘Well, I don't have a million dollars to fund that.' In a non-invasive device, any opportunity that you can have to test, even if it's this big, bulky thing, you can get some data.”Skribe Medical's technology can extend to other aspects of oncology, including peripartum cardiomyopathy, a rare form of heart failure arising towards the end of a pregnancy. Long-term, Neely envisions building the longitudinal training data needed for predictive monitoring. “What we'd like to do is be able to say, ‘two weeks from now there might be an issue' so you can do something today that prevents any drop [in injection fraction] at all.”Data that made the difference:Skribe Medical's three founders built first prototype at home. They used their home electronics and 3D printing labs to rapidly prototype the first functional sensors.Rapid wearable development delivered data quickly, first by testing themselves and then through clinical testing.Skribe Medical conducted the first clinical tests at an ECG lab where, with consent, the wearable collected patient data for comparison with the patient's ECG results.Having clinical data so early in the process encouraged investors. Last year's pre-seed round raised $1.6 million from angels and VCs to support the next phase of device development and trials.Listen to Andy's conversation with Neely to hear more about Skribe Medical's journey, development process, and the advantages of wearable medical technology.
In this episode, we sit down with Laurence Klein, Co-Founder and CEO of Nuvo, to explore how the FDA cleared INVU™ platform is reshaping maternal fetal surveillance and redefining the standard of care for pregnancy. Laurence traces the company's mission to replace episodic, clinic bound monitoring with continuous, medical grade prenatal care delivered at home or at work — and explains how that vision is now meeting a rapidly expanding commercial market. We cover: The Genesis of Nuvo — How a pregnancy wearable idea became a mission to decentralize prenatal care and put clinical-grade monitoring in the hands of expectant mothers wherever they are. The Biosensing Architecture — How INVU™'s passive array of ECG and PCG surface sensors, paired with cloud-based AI, achieves medical-grade fetal monitoring without active ultrasound — and what that means for accuracy, wearability, and scale. The Market Opportunity — Why the convergence of rural care gaps, urban lifestyle demands, and remote monitoring is creating a structural shift — not just a product category. Capital Strategy & What's Next — Deployment priorities following their Series A, the role of generative data pipelines in expanding clinical intelligence, and what institutional investors should be watching heading into the next growth round. Essential listening for anyone following the intersection of deeptech medical devices, digital health infrastructure, and AI-driven diagnostics.
On today's bonus episode of ECG the team discuss which historical moments would make for great video games, and Guy puts on his tinfoil hat. Hosted on Acast. See acast.com/privacy for more information.
On this week's episode of ECG, Guy uses a Beanie Baby to mop up vomit, Chris and Ellie argue over the Busch lobby and Producer JP shows off his MTG collection. Hosted on Acast. See acast.com/privacy for more information.
Navi Medical is an Australian medtech company with a very clear and compelling mission: to improve outcomes for some of the most vulnerable patients in our healthcare system—critically ill newborns and children. The company was founded on a simple but striking reality: many of the devices used in neonatal and paediatric care today are not designed for children at all, but adapted from adult medicine. In response, Navi has focused its efforts on developing purpose-built technologies for paediatric care, working closely with clinicians in neonatal and paediatric intensive care units to understand real-world challenges and design solutions that genuinely improve safety and outcomes. Navi's latest development is the Neonav device – an ECG tip-location system that improves umbilical monitoring for the most fragile neonatal patients. It achieved FDA registration in 2025.As CEO, Alex has led Navi from its early beginnings in Melbourne through to clinical development and commercialisation, building a multidisciplinary team spanning engineering, clinical care and business, all united by a shared goal: delivering brighter, healthier futures for children. Updated version 05/08/22
On today's bonus episode of ECG, the group attempt to discuss their favourite songs from video games without breaching copyright. Hosted on Acast. See acast.com/privacy for more information.
There's a new state law taking effect July 1st requiring all high school athletes to receive a heart screening before their first tryout. Sudden Cardiac Arrest is the number one killer of student-athletes and the leading cause of death on school campuses. Most students don't know whether they have a heart condition. We speak with Sara Goodrich, who oversees screenings for whoweplayfor.org to talk about why screenings are needed and where to find them in June. See omnystudio.com/listener for privacy information.
On this week's episode of ECG, Ellie “clears the air” around a nasty rumour that spread while she was away, Chris turns into a video game wedding planner, and Guy spills coffee on his new sweat shirt.This is a Frank Podcast Hosted on Acast. See acast.com/privacy for more information.
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Thank you and enjoy the episode!Links For The Occult Rejectshttps://linktr.ee/theoccultrejectsOccult Research Institutehttps://www.occultresearchinstitute.org/Cash Apphttps://cash.app/$theoccultrejectsVenmo@TheOccultRejectsBuy Me A Coffeebuymeacoffee.com/TheOccultRejectsPatreonhttps://www.patreon.com/TheOccultRejectsBibliographyThe Mechanics of Magick: Singing Bowls and the Ritual Physics of ResonanceCore Singing Bowl ResearchStanhope, Jessica, and Philip Weinstein. “The Human Health Effects of Singing Bowls: A Systematic Review.” Complementary Therapies in Medicine 51 (2020): 102412. Use for the honesty frame: promising findings around mental health and cardiovascular measures, but limited evidence and need for stronger study design.Cai, Yiqing, Guo-Yan Yang, Yibo Liu, Xiang-yun Zou, Heng Yin, Xinyan Jin, Xue-han Liu, Chenlu Wang, Nicola Robinson, and Jian-Ping Liu. “Therapeutic Effects of Singing Bowls: A Systematic Review of Clinical Studies.” Integrative Medicine Research 14, no. 2 (2025): 101144. Use for the newer clinical overview. Important correction: this appears as 101144, not 101176. Good for anxiety, depression, sleep quality, cognition, autistic behavior, and EEG-related outcomes while still keeping the evidence cautious.Lin, F. W., et al. “Effects of Tibetan Singing Bowl Intervention on Psychological and Physiological Health in Adults: A Systematic Review.” 2025. Useful as another recent review angle, especially for psychological health, physiological measures, HRV, and brainwave-related discussion. Keep it secondary behind Stanhope and Cai.Landry, Jayan Marie. “Physiological and Psychological Effects of a Himalayan Singing Bowl in Meditation Practice: A Quantitative Analysis.” American Journal of Health Promotion 28, no. 5 (2014): 306–309. Use for the controlled relaxation study: 51 participants, randomized crossover design, singing bowl exposure or silence before directed relaxation.Goldsby, Tamara L., Michael E. Goldsby, Mary McWalters, and Paul J. Mills. “Effects of Singing Bowl Sound Meditation on Mood, Tension, and Well-Being: An Observational Study.” Journal of Evidence-Based Complementary & Alternative Medicine 22, no. 3 (2017): 401–406. Use for reductions in tension, anger, fatigue, depressed mood, anxiety, and stress after singing bowl meditation. Good, but frame as observational, not definitive.Rio-Alamos, Cristina, et al. “Acute Relaxation Response Induced by Tibetan Singing Bowl Sounds: A Randomized Controlled Trial.” European Journal of Investigation in Health, Psychology and Education 13, no. 2 (2023): 317–328. Use for Tibetan singing bowl treatment compared with progressive muscle relaxation and a waiting-list control in anxious nonclinical adults.Walter, Nina, et al. “Neurophysiological Effects of a Singing Bowl Massage.” Medicina 58, no. 5 (2022): 594. Use for EEG, ECG, and respiration during singing bowl massage; the authors interpret the results as a shift toward a more mindful or meditative state.Goldsby, Tamara L., et al. “Mood, Emotional, and Spiritual Well-Being Interrelationships.” Religions 13, no. 2 (2022). Useful follow-up for spiritual well-being, emotional interpretation, and how people understand sound-healing experiences.Sound, Anxiety, HRV, and Brainwave CautionMallik, Adiel, and Frank A. Russo. “The Effects of Music & Auditory Beat Stimulation on Anxiety: A Randomized Clinical Trial.” PLOS ONE 17, no. 3 (2022): e0259312. Use this carefully for the broader point that sound-based treatments can reduce somatic and cognitive state anxiety. Do not use it as proof that singing bowls automatically entrain brainwaves.Ingendoh, Ruth Maria, Ella S. Posny, and Angela Heine. “Binaural Beats to Entrain the Brain? A Systematic Review of the Effects of Binaural Beat Stimulation on Brain Oscillatory Activity, and the Implications for Psychological Research and Intervention.” PLOS ONE 18, no. 5 (2023): e0286023. Very useful caution source. Use it when warning against overclaiming “brainwave entrainment” and frequency-healing claims.Vilímek, et al. 2022. Low-frequency sound / HRV / vibroacoustic-related research. Use cautiously if you want to discuss low-frequency vibration, body sensation, and autonomic response. I'd keep this as a secondary source unless you want a dedicated paragraph on vibroacoustics.Physics, Resonance, and CymaticsTerwagne, Denis, and John W. M. Bush. “Tibetan Singing Bowls.” Nonlinearity 24, no. 8 (2011): R51–R66. Use for the physics section: wall vibrations, water-surface waves, Faraday-wave effects, droplet motion, and the visible demonstration of resonance.Jenny, Hans. Cymatics: A Study of Wave Phenomena and Vibration. Newmarket, NH: MACROmedia, 2001. Use carefully for visual sound-pattern history. Good for imagery and occult imagination, but don't overuse it as clinical proof.Rossing, Thomas D. The Science of Sound. 3rd ed. San Francisco: Addison Wesley, 2002. Useful general acoustics source for resonance, overtones, vibration, sound waves, and instrument physics.Sound Baths, Wellness Culture, and Modern RitualSobo, Elisa J. “Sound Baths, Trauma Talk, and the Wellness Paradox in the USA.” Medical Anthropology 43, no. 5 (2024): 367–382. Excellent for the modern sound-bath/wellness-culture angle, especially trauma language, nervous-system talk, ritual performance, and how providers frame sound baths.Sobo, Elisa J. “A Beginner's Guide to Sound Baths — What They Are, How to Choose a Good One and What the Research Shows.” The Conversation (2024). Useful for accessible show-note language and ethical/practical framing.Sobo, Elisa J. “Healing Vibrations.” Anthropology News 64, no. 5 (2023): 28–32, 49. Good anthropology/public-facing source for sound healing and wellness culture.Tibetan Singing Bowls, History, and Cultural CommodificationGrimes, Samuel. “Where Did ‘Tibetan' Singing Bowls Really Come From?” Tricycle (2020). Use for the contested-history section. Strong source for questioning popular origin stories around “Tibetan” singing bowls.Joffe, Ben. “Anthropology and Tibetan Buddhism / Cultural Commodification / Tibetan Mystique.” 2015. Use for the larger argument about how Tibetan/Himalayan aura gets packaged in Western spiritual markets. Good support for the “Tibet as imagined storehouse of hidden wisdom” point.Scheidegger, Daniel A. “Tibetan Ritual Music.” Use for actual Tibetan Buddhist ritual sound: bells, cymbals, long horns, drums, chant, and liturgical soundscape. This helps separate real Tibetan ritual sound from overblown modern singing-bowl mythology.Lopez, Donald S. Prisoners of Shangri-La: Tibetan Buddhism and the West. Chicago: University of Chicago Press, 1998. Excellent support for Western romanticization of Tibet.Bishop, Peter. The Myth of Shangri-La: Tibet, Travel Writing, and the Western Creation of Sacred Landscape. Berkeley: University of California Press, 1989. Very useful for the “Tibet as fantasy geography” angle.Ritual, Sound, and Religious ExperienceEliade, Mircea. Shamanism: Archaic Techniques of Ecstasy. Princeton: Princeton University Press, 1964. Use carefully. Good for altered-state technologies and ritual sound/trance, but don't treat it as the final word on shamanism.Rouget, Gilbert. Music and Trance: A Theory of the Relations Between Music and Possession. Chicago: University of Chicago Press, 1985. Excellent for sound, music, trance, possession, rhythm, and ritual performance.Becker, Judith. Deep Listeners: Music, Emotion, and Trancing. Bloomington: Indiana University Press, 2004. Strong source for deep listening, music, emotion, trance, and the body.Husserl, Edmund. On the Phenomenology of the Consciousness of Internal Time. Useful if you want to get philosophical about tone, decay, waiting, and how sound reveals time.Ihde, Don. Listening and Voice: Phenomenologies of Sound. Albany: SUNY Press, 2007. Good for sound as experience, listening, voice, and embodied perception.Placebo, Meaning Response, and Healing RitualMoerman, Daniel E. Meaning, Medicine and the “Placebo Effect.” Cambridge: Cambridge University Press, 2002. Use for “meaning response” instead of treating placebo as “fake.”Benedetti, Fabrizio. Placebo Effects: Understanding the Mechanisms in Health and Disease. Oxford: Oxford University Press, 2009. Useful for placebo mechanisms, expectation, physiology, and therapeutic context.Kaptchuk, Ted J., and Franklin G. Miller. “Placebo Effects in Medicine.” New England Journal of Medicine 373 (2015): 8–9. Good short medical source for placebo effects as real psychobiological phenomena.Csordas, Thomas J. The Sacred Self: A Cultural Phenomenology of Charismatic Healing. Berkeley: University of California Press, 1994. Useful for healing, embodiment, ritual, and religious experience.Embodied Cognition, Extended Mind, and Ritual ToolsClAlso want to remind people about the website, if you're into reading we have tons of information by multiple contributors, and we got t-shirts up on the site if you're interested. Fun fact, the art is all based on the eyeball. A
Wat heb je aan een commerciële preventieve gezondheidscheck? De medische wereld is er kritisch over: zonder klachten testen levert volgens huisartsen en wetenschappers vooral ruis op, en de mensen die er het meeste baat bij zouden hebben, kunnen het vaak toch niet betalen. Toch poppen er steeds meer commerciële aanbieders van medische checks op in Nederland. Op de Amsterdamse Prinsengracht opende in maart Blue Health Intelligence, dat voor 299 euro tien medische testen in een uur aanbiedt. Is dit de toekomst van gezondheidspreventie? In deze aflevering van BNR Beter bespreekt Nina van den Dungen de opmars van commerciële preventieve gezondheidschecks. Te gast zijn Onno Huyghe, medeoprichter en co-CEO van Blue Health Intelligence, en Marco Blanker, hoogleraar huisartsgeneeskunde aan het UMCG en huisarts in Zwolle. Huyghe legt uit hoe Blue Health werkt: in een uur tijd doen klanten tien testen, waaronder bloedonderzoek, een 3D-bodyscan, een ECG, een echo van de halsslagader en een bloeddrukmeting. Daarna volgt een gesprek met een arts en een persoonlijk actieplan in een app. Bewust geen MRI, en daarmee een stuk goedkoper dan total bodyscans van rond 2.000 euro. Huyghe wil dat zo'n preventieve check over 40 tot 50 jaar standaard onderdeel is van het huisartsbezoek, en dat zorgverzekeraars het op termijn vergoeden. Blanker steunt het uitgangspunt dat Nederland meer aan preventie moet doen, maar plaatst stevige kanttekeningen bij de uitvoering. Een ECG of echo bij iemand zonder klachten heeft volgens hem geen aangetoonde meerwaarde boven kennis van de bekende risicofactoren als roken, gewicht, bloeddruk en cholesterol. Diagnostiek is ontwikkeld voor mensen met klachten; bij gezonde mensen kan dezelfde test andere uitkomsten opleveren. Hij wijst daarnaast op vals-positieve uitslagen die alsnog bij de huisarts terechtkomen, en op vals-negatieve uitslagen die juist schijnveiligheid geven. Een tweede knelpunt is de doelgroep. Volgens Blanker bereikt een commerciële aanbieder vooral mensen die al met hun gezondheid bezig zijn, terwijl de gezondheidswinst juist bij kwetsbaardere groepen valt te halen. Huyghe erkent dat Blue nu de 'voorlopers' aantrekt, maar gelooft dat de aanpak op termijn wel breder kan werken. Verder gaat het over de vraag of structurele maatregelen als een suikertaks of een leeftijdsgrens voor roken effectiever zijn dan losse health checks, en over hoe je leefstijlverandering daadwerkelijk in gang zet. Over deze podcast BNR Beter is het wekelijkse programma van BNR Nieuwsradio over een toekomstbestendige zorgsector. Elke week bespreekt presentator Nina van den Dungen met zorgprofessionals, ondernemers en beleidsmakers hoe de Nederlandse zorg met technologie, innovatie, regelgeving en wetenschap beter kan worden. BNR Beter is elke maandag om 15:30 op de radio te beluisteren bij BNR Nieuwsradio, en vanaf dat moment ook als podcast via deze feed. Over de makers Nina van den Dungen (1987) is freelance journalist en als radio- en podcastpresentator al ruim 15 jaar verbonden aan BNR. Zo is ze regelmatig te horen als presentator van de nieuwsprogramma's in de ochtend- en avondspits en daarnaast presenteert ze wekelijks de beleggingspodcast Doorgelicht en BNR Beter over de zorgsector. Stijn Goossens (1996) is de redacteur van BNR Beter en plaatsvervangend presentator. Bij BNR houdt Stijn zich bezig met onderwerpen over tech, wetenschap en innovatie. Hij presenteert ook de podcast Op de zaak en test elke vrijdag een nieuw techproduct in de Ochtendspits op BNR. Hiervoor was Stijn werkzaam voor NTR Wetenschap en techplatform Bright.See omnystudio.com/listener for privacy information.
V tomto podcaste sa pozrieme na štúdie, ktoré vyhodnocovali, nakoľko presne merajú smart hodinky rôzne biologické parametre. Zdroje Accuracy of VO2 max Estimates From Apple Watch Series 10 Validity of V̇O2max estimates from the forerunner 245 smartwatch in highly vs. moderately trained endurance athletes Comparative Validity of Smartwatch-Derived Heart Rate and Energy Expenditure During Endurance and Resistance Exercise Assessing the Accuracy of Smartwatch-Based Estimation of Maximum Oxygen Uptake Using the Apple Watch Series 7: Validation Study Investigating the accuracy of Apple Watch VO2 max measurements: A validation study Validity of V̇O2max estimates from the forerunner 245 smartwatch in highly vs. moderately trained endurance athletes Validity of Wrist-Worn Activity Trackers for Estimating VO2max and Energy Expenditure A guide to consumer-grade wearables in cardiovascular clinical care and population health for non-experts Validity of four low-cost smartwatches in estimating energy expenditure during cycling in Chinese untrained women Performance evaluation of smartwatches: Can they match clinical standards for ECG analysis? - ScienceDirect Image by Carlos Zuniga from Pixabay
A coronariografia veio normal. Mas o paciente continua com dor, teste isquêmico positivo e qualidade de vida no chão. O que você está deixando de investigar?Neste episódio, Mateus Prata e Raphael Rossi mergulham na fisiologia invasiva da microcirculação coronariana — o território que a angiografia simplesmente não enxerga. Falamos sobre INOCA, ANOCA, disfunção microvascular e espasmo coronariano: por que esses diagnósticos ainda escapam e como o teste fisiológico invasivo pode mudar o rumo clínico de forma concreta.
On today's bonus episode of ECG, the group tackle a topic sent in by a listener - What video game tropes would you add to your vehicle in real life? Hosted on Acast. See acast.com/privacy for more information.
On this week's episode of ECG, Guy's Pokemon card addiction reaches new heights, Chris is a shell of a human and Ellie invites the entire team to her future wedding. Hosted on Acast. See acast.com/privacy for more information.
On today's bonus episode of ECG, the group discuss nicknames and Guy wastes everyone's time failing at wordle. Hosted on Acast. See acast.com/privacy for more information.
On this weeks episode of ECG, Pugs changes the tone of the podcast, Guy makes some serious coin on Pokemon cards and Chris asks the big question; will they be invited to Ellie's wedding? Hosted on Acast. See acast.com/privacy for more information.
On today's bonus episode of ECG, Chris and Guy discuss their “ideal” gaming scenarios and things quickly get off topic. RIP Plum. Hosted on Acast. See acast.com/privacy for more information.
On this weeks episode of ECG, Ellie gets mistaken for a toddler, Guy reconnects with a childhood passion and Chris organises an incredibly stressful video game holiday. Hosted on Acast. See acast.com/privacy for more information.
From building a 100 kilowatt solar powered fish farm with greenhouses to understanding why most Ghanaian companies die with their founders, and why the brutal truth about entrepreneurship is that creating generational wealth means moving away from the one man show mentality where if you're not here the business cannot survive because knowledge and wisdom doesn't reside in only one person and you need to put structures in place that allow the company to thrive even when you're gone which is exactly what happened to great companies in Ghana set up by people from Makropom and other places where when the founder passed away the company died because maybe the structure wasn't great and somebody took over and said I'm not going to do this leaving workers jobless proving that without proper management and vision the business collapses with the founder, the entrepreneur who studied Japanese companies like Toyota Honda Suzuki Panasonic and Sony where one guy started it the structure was there his son became boss his grandson became boss and the family has interests but because the structure is solid the company survives for generations teaching that generational wealth creation is not just about making money but about building something that will take care of your wife your daughters your grandchildren and provide jobs for workers long after you're gone, the fish farmer who decided to breed fish in tanks under tunnels in greenhouses so workers can go in anytime even when it's raining and built his own hatchery for constant supply of fingerlings because selling raw fish makes some money but processing the fish drying it and packaging it with machines is where the margins are high, the businessman who brought in machines to dry and package fish but admits he made a mistake not securing offtakers before starting the project because he was not living in Ghana and didn't trust people to do the research for him and the industry is so fragmented with everybody claiming they're doing 1,000 catfish or 5,000 fish and there are so many lies on YouTube with people getting caught thinking if they buy 1,000 catfish they'll make this amount of money when it's not like that and unfortunately people are falling for such advice, the solar power advocate who saw that energy cost is very high in Ghana and in Asia where he worked in Japan electricity for industrial use is actually cheaper than electricity for households and Singapore is even cheaper but in Ghana it's not like that making it nearly impossible to grow industries with such high cost of power which is why he installed 100 kilowatt solar on his farm to power everything with ECG as backup and two generators as additional backups, the aquaponics dreamer who initially wanted fish water to flow through floating beds where you plant lettuce on styrofoam and the plants pick up the nitrates filtering the water so you don't waste a lot of water and only top up every three months while harvesting vegetables but decided Ghanaians don't eat vegetables so he converted everything into tanks and got stuck with waste water wondering what to do instead of flushing it into gutters like some people do, the innovator who built greenhouses and directed waste water into tanks to irrigate them now producing red and yellow bell peppers after doing tomatoes and cucumbers and buying three more greenhouses from a supplier that will be installed soon bringing the total to six greenhouses optimizing revenue by going back to competency and figuring out which vegetables to grow, the realization that an old friend told him something funny that a man going into retirement is more concerned about losing their money than their life and at this age how long is he going to live so what is he leaving behind for his wife his daughters his future grandchildren. Host: Derrick Abaitey
AI ECG for Valvular Disease and Diastolic Function Guest: Jae Oh, M.D. Host: Kyle Klarich, M.D. In this episode of “Interview With the Experts,” Dr. Kyle Klarich interviews Dr. Jae Oh on the use of AI ECG in his practice. ECG is widely available and standardized. AI ECG can be used for screening important left heart conditions and helpful in identifying asymptomatic patients with significant diastolic dysfunction or aortic stenosis. AI ECG can be a useful prognostic parameter when applied appropriately. Topics Discussed: How did you get involved in AI ECG for diastolic function and AS? How did you develop AI ECG algorithms? How does AI ECG perform for diastolic function and AS? What do you think is the optimal clinical application of AI ECG? Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode. Podcast episode transcript found here. Recorded on: 02-October-2025
In this episode of the DocPreneur Leadership Podcast, host Michael Tetreault sits down with Alex Muckerman, Senior Manager at ECG Management Consultants, for a candid, strategy-first conversation about how health systems are thinking about — and in some cases, finally acting on — concierge and membership-based medicine as a legitimate service line. Alex brings a rare combination of management consulting rigor and deep operational knowledge of the concierge medicine landscape. He's worked with health systems and medical groups across the country, designing and implementing customized concierge and direct primary care models that are built to last — not just to check a box. In this conversation, we cover: Why more health systems are taking concierge medicine seriously right now What a well-designed concierge medicine service line actually looks like How to align a concierge model with your organization's broader ambulatory strategy The common mistakes health systems make when entering this space What physicians inside large systems need to understand about this shift And what the evolving primary care market means for the future of relationship-based medicine Whether you're a physician entrepreneur, a practice leader, or a health system executive, this is a conversation worth your time. ABOUT ALEX MUCKERMAN Alex Muckerman is a Senior Manager at ECG Management Consultants, a national leader in healthcare business strategy and one of the most respected management consulting firms in the industry. Alex brings more than eight years of combined experience across ambulatory strategy, medical group operations, provider compensation, revenue cycle management, and concierge medicine practice model development. He specializes in conducting data-driven ambulatory enterprise performance evaluations and has led practice assessments and financial turnaround initiatives for organizations ranging from large, multispecialty health system–owned medical groups to small independent practices. He has extensive expertise in concierge medicine service line development and implementation, and is recognized for his ability to design customized concierge and direct primary care business models that meet patient demand while generating sustainable financial returns. Alex holds an MBA in Healthcare Management, Strategy, and Consulting from Washington University in St. Louis — Olin Business School, and previously served as a consultant at Booz Allen Hamilton, where he worked with the Veterans Health Administration on clinical and financial systems development. He is a thoughtful voice on how health systems can approach membership-based medicine not as a trend — but as a strategic imperative. CONNECT WITH ALEX MUCKERMAN & ECG
On today's Bonus Episode of ECG, Ellie uses video game references to brag about her upcoming trip to Europe! Hosted on Acast. See acast.com/privacy for more information.
On this week's episode of ECG, Ellie shows off her improv skills, Guy is a bit too fast and furious; and Chris activates hardcore mode in real life! Hosted on Acast. See acast.com/privacy for more information.
On today's bonus episode of ECG, listener Thomas sends through a word game for the gang to tackle. Hosted on Acast. See acast.com/privacy for more information.
LISTENER DISCRETION IS ADVISED. Sensitive themes. Language. References: Rautaharju PM, Park L, Rautaharju FS, Crow R. A standardized procedure for locating and documenting ECG chest electrode positions: consideration of the effect of breast tissue on ECG amplitudes in women. J Electrocardiol. 1998 Jan;31(1):17-29.
Mark Lindsey, Analyst and Engineer at ECG, spoke with Doug Green, Publisher of Technology Reseller News, during the Channel Partners Conference & Expo about how AI is transforming call intelligence and post-call workflows for businesses and MSPs. Lindsey described ECG's approach to capturing and analyzing conversations, turning voice interactions into structured data that can be immediately acted upon. By leveraging AI, ECG enables automatic transcription, summarization, and extraction of key action items from calls, helping organizations streamline follow-up and improve accountability. “We're turning conversations into actionable intelligence that can be shared and used instantly,” Lindsey said. The platform goes beyond simple transcription by organizing insights into clear outputs such as summaries, tasks, and next steps. This allows teams to quickly understand what happened during a call and what needs to happen next, reducing manual effort and improving operational efficiency. The discussion also highlighted how these capabilities benefit MSPs and channel partners by enhancing customer engagement and internal workflows. By automating routine tasks and providing clearer visibility into communications, organizations can improve productivity while delivering a better customer experience. As conversations at Channel Partners continue to focus on AI and automation, ECG is positioning its solution as a practical way to bring intelligence and structure to everyday business communications. Learn more about ECG: https://www.ecg.co/
Padrões de oclusão coronariana aguda no ECG by Cardiopapers
On this week's episode of ECG, Ellie has an unconventional idea to boost publicity, Chris prepares for a video game cyclone and Guy goes trick or treating. Hosted on Acast. See acast.com/privacy for more information.
Join host Melissa Middeldorp and her guests Marco Perez and Kristie Coleman for this installment of The Lead! This multicenter randomized controlled trial evaluated whether smartwatch-based rhythm monitoring improves detection of previously undiagnosed atrial fibrillation (AF) in cardiology outpatients aged ≥65 years with elevated stroke risk. A total of 437 participants were randomized to either 6-month monitoring with an Apple Watch integrating photoplethysmography-based irregular rhythm detection and single-lead ECG confirmation, supported by a telemonitoring adjudication pathway, or to standard care. The primary endpoint of new AF occurred significantly more often in the intervention group than in controls (9.6% vs 2.3%; HR 4.40), with many cases asymptomatic and detected earlier through wearable monitoring. All diagnosed patients were initiated on anticoagulation, and major adverse cardiovascular events were similar between groups. Overall, the study demonstrates that prolonged smartwatch-based screening embedded within a clinical workflow substantially increases AF detection in a high-risk population, highlighting the feasibility of wearable-enabled case finding while underscoring ongoing questions regarding clinical outcomes and optimal implementation. Learning Objectives Describe the design and key findings of a randomized trial evaluating smartwatch-based screening for atrial fibrillation in older patients at elevated stroke risk. Discuss the clinical implications, limitations, and broader evidence context of wearable-enabled atrial fibrillation detection within contemporary screening strategies. Article Authors Nicole J. van Steijn, Isabel S. Blommestijn, Sebastiaan Blok, Shari Pepplinkhuizen, Aernout Somsen, Reinoud E. Knops, Laura Breukel, Jan G.P. Tijssen, Igor I. Tulevski, Philip M. Croon, Michiel M. Winter Podcast Contributors Melissa E. Middeldorp, MPH, PhD Kristie Coleman, MPH, RN Marco Perez, MD Host and Contributor Disclosure(s): M. MiddeldorpNothing to disclose. K. Coleman •Honoraria/Speaking/Teaching/Consulting: Medtronic M. Perez •Honoraria/Teaching/Speaking/Consulting: Boston Scientific, Biontronik •Ownership/Partnership: QALY •Research: Apple, Inc.
On today's bonus episode of ECG, the gang discuss the best bug screen adaptations of video games, and vice versa. Hosted on Acast. See acast.com/privacy for more information.
On this week's episode of ECG, Chris opens a delicious video game restaurant, Ellie considers BBQing horses and Guy wears his anxiety cardigan. Hosted on Acast. See acast.com/privacy for more information.
Podcast family we've all heard the rumors that oursmartphones are “LISTENING TO US”. Well, some of that is actually true, and trust me I'm not a conspiracy theorist. Our smartphones are capable of remarkable things. A new publication from the Green journal (released ahead ofprint on 03/05/2026 ) is proposing that it may now be able to detect fetal movement, fetal breathing, and even fetal hiccups when placed over the abdomen! Yep, it's not science fiction... it's science innovation. While this is not ready for prime time just yet, the science is absolutely astounding. In this quicky episode we will briefly summarize a fascinating new innovative study which proposes that our iPhones may be able to be a fetal movement detector.1. Moise, Kenneth Jr MD; Gaither, Kelly PhD;Madden-Rusnak, Anna PhD; Lowry, Kathy RN, MSN; Hutson, Emily RN, MSN; Bruns, Danielle RDMS; Valero, Reinaldo MD, RDMS. Smartphone Detection of FetalMovements Using Artificial Intelligence. Obstetrics & Gynecology ():10.1097/AOG.0000000000006228, March 5, 2026. | DOI:10.1097/AOG.00000000000062282. Lai J, Woodward R, Alexandrov Y, et al Performanceof a Wearable Acoustic System for Fetal Movement Discrimination. PloS One. 2017. 3. Ashik AK, Gutierrez R, Ashraf F, et al. AMachine Learning Model for Assessing Fetal Health During Pregnancy. Frontiers in Bioengineering and Biotechnology. 2025. 4. Antepartum Fetal Surveillance: ACOG PracticeBulletin, Number 229. Obstetrics and Gynecology. 2021.5. Monitoring a Pregnancy at Home With a SmartphoneThis wearable device provides real-time ECG monitoring of a fetus: https://spectrum.ieee.org/pregnancy-heartbeat-monitor-smartphone
Real Life Pharmacology - Pharmacology Education for Health Care Professionals
In this episode, we are going to review antiarrhythmic drugs that clinicians may encounter in practice: Digoxin, Propafenone, Dofetilide, and a few others. While these drugs are commonly used in the management of atrial fibrillation and other rhythm disturbances, they each come with important pharmacology and safety considerations that pharmacists and healthcare providers need to recognize. Digoxin is a cardiac glycoside that increases contractility while also slowing AV node conduction through enhanced vagal tone, making it useful for rate control in atrial fibrillation, particularly in patients with heart failure. However, it has a narrow therapeutic index, and toxicity can occur if renal function declines or electrolyte abnormalities develop. Propafenone is a Class IC sodium channel blocker used primarily for rhythm control in atrial fibrillation. A key clinical pearl with this medication is that it should generally be avoided in patients with structural heart disease due to the risk of proarrhythmia. Dofetilide and sotalol are both Class III antiarrhythmics that work by blocking potassium channels and prolonging cardiac repolarization. Because of their ability to prolong the QT interval, both agents carry a risk of torsades de pointes and require careful monitoring. Dofetilide initiation typically requires hospitalization to monitor the QT interval and adjust dosing based on renal function. Sotalol also requires attention to renal function and ECG monitoring, and it has additional beta-blocking effects that can contribute to bradycardia and fatigue. Throughout this episode, we will break down the mechanisms, common clinical uses, and key safety pearls for these medications to help you better understand how they fit into arrhythmia management. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources! NAPLEX Study Materials BCPS Study Materials BCACP Study Materials BCGP Study Materials BCMTMS Study Materials Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101
Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Antiarrhythmic medications are some of the most complex and high-risk drugs pharmacists encounter in clinical practice. In this episode, we break down the most important concepts pharmacists need to understand about antiarrhythmics, including the major drug classes and the clinical situations where these medications are commonly used. A major focus of the discussion is medication safety. Many antiarrhythmics carry risks such as QT prolongation, proarrhythmia, and significant drug–drug interactions. Pharmacists play a critical role in identifying these risks, monitoring electrolytes and ECG changes, and recognizing situations where therapy adjustments are necessary. We also highlight why certain medications require inpatient initiation and careful monitoring. The episode also covers practical clinical pearls, including the unique toxicity profile and interaction potential of amiodarone, how to think about rate control versus rhythm control strategies in atrial fibrillation, and the most common medication-related problems pharmacists should watch for. Whether practicing in ambulatory care, hospital, or long-term care settings, understanding antiarrhythmics can help pharmacists prevent serious complications and improve patient outcomes. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources! NAPLEX Study Materials BCPS Study Materials BCACP Study Materials BCGP Study Materials BCMTMS Study Materials Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101