Podcasts about ecg

This month we have three really clinically relevant papers that take us from a very common ED presentation, through an everyday diagnostic dilemma, and then right into a high-risk paediatric airway. We start with abdominal pain in older adults and ask whether the history and examination are giving us as much reassurance as we think. The paper looks at how CT use, diagnostic yield, admission and surgery change with age - and whether we should think of geriatric abdominal pain as a distinct high-risk presentation. Then move on to unexplained syncope and a large UK randomised trial of immediate 14-day ambulatory ECG monitoring. The didn't reduce recurrent syncope at one year, but it found substantially more clinically significant arrhythmias, found them earlier and led to more treatment. That leaves us with a really interesting question about the difference between diagnosing more disease and improving the outcome the patient actually experiences. What will it mean for our strategies moving forwards? Finally, we look at paediatric emergency intubation through recorded video laryngoscopy. Which technical errors occur most often, which ones cluster around failure, and what can the airway coach spot early enough to change the attempt? As ever, we will take you through what the teams did, what they found, and whether any of it should change practice on your next shift. Once again we'd love to hear any thoughts or feedback either on the website or via X @TheResusRoom! Simon & Rob

AliveCor built its name on a single-lead ECG that let ordinary people check their heart rhythm at home. In this episode, CEO Priya Abani explains how the company is now building a healthcare enterprise business around a newly cleared 12-lead device, a GE Healthcare integration and a Medicare program, while its consumer business keeps growing and its long legal fight with Apple continues. Key Takeaways The 12-lead expands the market rather than replacing the hospital cart. Cleared for 39 cardiac conditions, including heart attacks, the device goes where a $15,000 to $20,000 ECG cart never did: primary care, concierge medicine, urgent care, hospital at home and even dentist offices. Integration is the answer to the point-solution problem. AliveCor is building into GE Healthcare's Muse platform, which sits in 87% of large US hospital systems, and is choosing EHR partners carefully for new markets. The consumer business funds the enterprise push. Gross profit from direct-to-consumer sales is being reinvested in the healthcare enterprise, employer and payer, and biopharma channels instead of chasing profitability right now. Engagement comes from a path forward, not just a diagnosis. About 350,000 KardiaCare subscribers take roughly 30 ECGs a quarter, and that base became the testing ground for blood pressure and diabetes services. Medical grade is the dividing line. Priya argues the winners will be the companies that clearly separate wellness tech from FDA-cleared, clinically validated AI. Links and Resources Connect with Arundhati Parmar: aparmar@medcitynews.com Arundhati Parmar (@aparmarbb) on X: https://twitter.com/aparmarbb?lang=en MedCity News: https://medcitynews.com/ AliveCor research library (mentioned in the episode): alivecor.com/research Keywords AliveCor, Priya Abani, KardiaMobile, 12-lead ECG, portable ECG device, personal ECG, consumer wearables to enterprise, digital health business model, FDA-cleared ECG AI, GE Healthcare Muse integration, medical-grade AI, remote cardiac monitoring, atrial fibrillation detection, KardiaCare subscription, Kardia Access Medicare, cardiometabolic care, AliveCor Apple lawsuit, point-of-care ECG, MedCity Pivot podcast Episode Highlights [00:02:10 - 00:03:40] Priya runs the numbers: 400 million ECG recordings, 6.4 million patients, nearly 40 countries. [00:03:40 - 00:04:20] The 12-lead device is cleared for 39 cardiac conditions, including heart attacks. [00:05:15 - 00:06:00] A pocket-sized 12-lead opens up dentist offices, airplanes, cargo ships and schools. [00:10:40 - 00:11:45] How the GE Healthcare Muse integration answers the point-solution problem. [00:15:20 - 00:16:15] Why a 12-lead ECG that doesn't require disrobing matters for women around the world. [00:18:30 - 00:20:00] Priya on a 180-person company standing up to the largest corporation in the world. [00:23:30 - 00:24:30] Printing every customer review and highlighting what patients wanted next. [00:30:15 - 00:32:00] Clinical AI versus LLMs, and why Ask Kardia only talks about heart health.  

Recorded at Trauma 2030 at the Royal College of Surgeons in London in December 2025, this short St Emlyn's podcast looks at one of the most challenging situations in prehospital and emergency care: traumatic cardiac arrest. Iain is joined by Laura Kocierz, a Consultant with London's Air Ambulance and a Consultant in Critical Care Medicine and Anaesthesia in the Midlands. In this conversation, Laura and Iain explore how data can help us make better decisions about resuscitative thoracotomy. Traumatic cardiac arrest is not always a simple binary event. Patients may deteriorate through a profound low-output state before complete circulatory arrest, and recognising the underlying cause quickly is critical. Laura discusses how the surface location of a penetrating injury can help distinguish cardiac tamponade from exsanguination. A wound within the cardiac box or epigastrium carries a substantially higher likelihood of tamponade, making immediate thoracotomy an important consideration when an organised cardiac rhythm remains. The conversation also explores the ECG as a potential surrogate for time since traumatic cardiac arrest. Sinus rhythm, bradycardia, agonal complexes and asystole may represent progressive physiological deterioration and can add useful information when the reported timing of arrest is uncertain. This leads to an important challenge to the traditional “15-minute rule”. If the history suggests a prolonged arrest but the patient has a penetrating injury consistent with tamponade and still has an organised rhythm, Laura explains why the physiological evidence may be more useful than an uncertain reported time. The other key message is equally important: resuscitative thoracotomy is not a treatment for exsanguination. When major blood loss is the likely cause, priorities remain haemorrhage control, blood transfusion and rapid access to definitive care, while continuing to look actively for co-existing tamponade. In this podcast: Defining traumatic cardiac arrest as a clinical and physiological state Using wound location to estimate the likelihood of cardiac tamponade The significance of penetrating injury within the cardiac box and epigastrium Using ECG rhythm as a clue to the duration of circulatory arrest Why reported arrest times may be unreliable Rethinking the traditional 15-minute threshold for resuscitative thoracotomy Distinguishing tamponade from exsanguination Why thoracotomy should not distract from haemorrhage control and blood transfusion How data from London's Air Ambulance is helping make traumatic cardiac arrest care more targeted A short conversation with some important practical challenges to the way we think about traumatic cardiac arrest, particularly when deciding who may genuinely benefit from resuscitative thoracotomy. Learning from podcasts? If podcasts form part of your CPD, you can log your listening time across all podcasts on MedPod Learn — not just St Emlyn's — and generate structured reflection. The app is free to download, includes a one-month free trial, and offers globally adjusted pricing. Trauma 2030 TRAUMA 2030 united experts and innovators to shape the future of trauma care. Over two days, it explored breakthroughs in science, systems, and frontline practice, fostering collaboration across disciplines. The symposium aimed to inspire research, inform policy, and build a bold roadmap for trauma care worldwide.

Your heart has its own rhythm, but what happens when that rhythm becomes too fast, too slow or irregular? This Heart Awareness Month, we turn the focus to arrhythmias as heart rhythm disorders can sometimes go unnoticed. We unpack the signs to look out for, why atrial fibrillation can increase your risk of stroke, how an irregular heartbeat is diagnosed, and the treatment options available to help keep your heart on beat. Early Breakfast with Africa Melane is 702’s and CapeTalk’s early morning talk show. Experienced broadcaster Africa Melane brings you the early morning news, sports, business, and interviews politicians and analysts to help make sense of the world. He also enjoys chatting to guests in the lifestyle sphere and the Arts. All the interviews are podcasted for you to catch-up and listen. Thank you for listening to this podcast from Early Breakfast with Africa Melane For more about the show click https://buff.ly/XHry7eQ and find all the catch-up podcasts here https://buff.ly/XJ10LBU Listen live on weekdays between 04:00 and 06:00 (SA Time) to the Early Breakfast with Africa Melane broadcast on 702 https://buff.ly/gk3y0Kj and CapeTalk https://buff.ly/NnFM3N Subscribe to the 702 and CapeTalk daily and weekly newsletters https://buff.ly/v5mfetc Follow us on social media: 702 on Facebook: https://www.facebook.com/TalkRadio702 702 on TikTok: https://www.tiktok.com/@talkradio702 702 on Instagram: https://www.instagram.com/talkradio702/ 702 on X: https://x.com/Radio702 702 on YouTube: https://www.youtube.com/@radio702 CapeTalk on Facebook: https://www.facebook.com/CapeTalk CapeTalk on TikTok: https://www.tiktok.com/@capetalk CapeTalk on Instagram: https://www.instagram.com/ CapeTalk on X: https://x.com/CapeTalk CapeTalk on YouTube: https://www.youtube.com/@CapeTalk567 See omnystudio.com/listener for privacy information.

En este Manzanas Informadas repasamos varias historias que dejan bastante claro que una nueva generación de dispositivos no siempre consiste simplemente en añadir funciones.Hablamos de las primeras pruebas de refrigeración del iPhone 18 Pro Max y de cómo se comporta el A20 Pro cuando se lleva su sistema térmico al límite.También nos detenemos en el nuevo sensor cardiaco del Apple Watch Series 12, con las primeras pruebas independientes frente a una banda pectoral ECG y una pregunta importante: ¿realmente mide mejor que el Series 11 o la gran mejora está en poder medir mucho más a menudo durante todo el día?Y precisamente en el Apple Watch encontramos también una ausencia curiosa: una función que llevaba varios años entre nosotros ya no aparece disponible en los Series 12 y Ultra 4.Terminamos viajando hasta India, donde el llamado quick commerce ha conseguido algo bastante llamativo: que un iPhone recién lanzado pueda llegar a casa en apenas unos minutos.Además, este viernes 25 de septiembre llegaremos a una cifra muy especial: 1.000 programas de Manzanas Enfrentadas, sumando MI, ME-RO y ME.Fuentes del episodio• Refrigeración del iPhone 18 Pro Max y A20 Pro:https://wccftech.com/iphone-18-pro-max-vapor-chamber-cooling-matches-android-gaming-phones/• Prueba extrema del A20 Pro con nitrógeno líquido:https://wccftech.com/a20-pro-vapor-chamber-peak-performance-upgrade-liquid-nitrogen-cooling-test/• Primeras pruebas del nuevo sensor cardiaco del Apple Watch Series 12:https://9to5mac.com/2026/09/18/the-quantified-scientist-tests-the-apple-watch-series-12s-new-heart-rate-sensor/• Ausencia de la detección de lavado de manos en Series 12 y Ultra 4:https://9to5mac.com/2026/09/19/apple-watch-series-12-ultra-4-missing-one-health-feature/• iPhone entregados en pocos minutos en India:https://techcrunch.com/2026/09/18/in-india-the-new-iphone-can-arrive-faster-than-a-pizza/Síguenos y participaBluesky: @menfrentadas.bsky.socialX: @MEnfrentadasMastodon: @ManzanasEnfrentadas@mas.toThreads: @manzanasenfrentadasTikTok: @manzanasenfrentadasTelegram: @manzanasenfrentadasGracias, como siempre, a todos los que nos escucháis, compartís el programa y formáis parte de la comunidad de Manzanas Enfrentadas.Música: “Helado de Cereza Loop 1” — FiftySoundshttps://www.fiftysounds.com/

When does a raised troponin become a myocardial infarction? What has happened to “type 2 MI”? And how certain can we be about the diagnosis without imaging? Iain Beardsell introduces Professor Rick Body for a practical guide to the Fifth Universal Definition of Myocardial Infarction. Rick explains the changes in terminology, troponin interpretation and diagnostic criteria, focusing on what they mean for clinicians assessing patients in the emergency department. What Rick covers Primary, secondary and procedure-related MI. The new classification replaces the previous numbered types. Rick explains why primary MI now includes coronary dissection, vasospasm and embolism, alongside atherothrombosis. He also describes how the 30-day window after coronary intervention or bypass surgery defines procedure-related MI. Sex-specific troponin thresholds. The definition explicitly recommends sex-specific upper reference limits. Rick discusses why this matters and encourages clinicians to understand the thresholds used by their own laboratory, rather than assuming every troponin assay works in the same way. A likely diagnosis versus a confirmed diagnosis. Cardiac and coronary imaging take a more prominent role in confirming MI and identifying its cause. This is particularly relevant when considering secondary MI in patients with sepsis, tachyarrhythmia or gastrointestinal haemorrhage. A troponin rise alone does not establish myocardial infarction. Acute and chronic myocardial injury. Rick explores the causes of myocardial injury beyond infarction, including inflammation, haemodynamic stress, catecholamine effects, toxicity and trauma. He also challenges the habit of diagnosing chronic myocardial injury from two similar troponin results during an acute ED attendance, without establishing the patient's stable baseline or investigating the underlying cause. Making sense of the troponin delta. Absolute changes, percentage changes, the starting concentration, time from symptom onset and the interval between samples all influence interpretation. Rick explains why there is no single delta that works for every patient, and why sampling intervals must match the evidence supporting the thresholds being used. STEMI, NSTEMI and occlusive MI. The traditional terminology remains, but the definition recognises important ECG patterns beyond conventional ST elevation. Rick discusses the place of posterior MI, de Winter T waves, Wellens syndrome, the Aslanger pattern and Sgarbossa criteria within this evolving approach. The episode also considers the practical consequences of these changes. More investigation brings additional resource demands, and Rick highlights the uncertainty about whether a more extensive assessment of chronic myocardial injury will improve patient outcomes. More from the accompanying blog Professor Nick Mills, first author of the new definition, adds an important clarification: a working clinical diagnosis can guide initial treatment. Imaging helps identify the cause and improve diagnostic certainty, but unavailable or inappropriate angiography does not prevent a clinical diagnosis. In secondary MI, managing the presenting illness remains the immediate priority. Rick also notes that HEART, T-MACS, EDACS and MI-3 are not addressed in the document. He interprets this as being outside its scope, rather than a change to their use. The post includes Rick's video presentation and details of ADOPT-UDMI, an education, evaluation and research programme inviting clinicians from all specialties to help put the new classification into practice. Read the full post: The Fifth Universal Definition of Myocardial Infarction: What Emergency Clinicians Need to Know Learning from podcasts? If podcasts form part of your CPD, MedPod Learn brings together St Emlyn's and other medical podcasts. Browsing and listening are free. Premium adds listening-time tracking, MCQs, structured reflection prompts and an exportable learning record for CPD and appraisal, with globally adjusted pricing.

This episode is part of our comprehensive Decipher the Guidelines Series covering the 2025 ACC/AHA/ACEP/NAEMSP/SCAI Guideline for the Management of Patients With Acute Coronary Syndromes.  The following question refers to Section 3.2 of the 2025 ACS Guidelines. The question is asked by Thomas Jefferson medical student and CardioNerds Academy Intern Dr. Grace Qiu, answered first by Cleveland Clinic interventional and structural cardiology fellow and member of the CardioNerds Interventional Cardiology Council Dr. Eunice Dugan, and then by expert faculty Dr. Binita Shah. Dr. Binita Shah is an associate professor of medicine, interventional cardiologist, Director for research in Interventional Cardiology, and Director of the Department of Medicine Clinical Investigator Track at NYU. She is also an associate director of interventional cardiology and director of the transcatheter valve program at the VA New York Harbor Healthcare System. She was a member of the 2025 ACS Guidelines writing committee. Question #3 A 55-year-old woman is brought to the Emergency Department after an out-of-hospital cardiac arrest. She had a witnessed collapse with an initial shockable rhythm. Return of Spontaneous Circulation (ROSC) was achieved after 15 minutes of Advanced Cardiac Life Support (ACLS). Her post-resuscitation ECG shows diffuse ST-segment depression but no ST-segment elevation. She remains comatose. Which of the following is the most appropriate next step in her management regarding coronary angiography? A Immediate emergency coronary angiography (within 2 hours) should be performed. B Routine emergency coronary angiography is not recommended in the absence of ST-segment elevation or hemodynamic instability. C Coronary angiography should be delayed for at least 72 hours to allow for neurological recovery. D Fibrinolytic therapy should be administered immediately if the patient cannot reach a cath lab within 90 minutes. Answer #3 Explanation The correct answer is B. In resuscitated patients who are comatose after cardiac arrest, electrically and hemodynamically stable, and without evidence of STEMI, immediate angiography is not recommended due to lack of benefit (Class 3: No Benefit; LOE A) Patients who have been resuscitated after cardiac arrest and are noncomatose or who are comatose with favorable prognostic features and with evidence of STEMI, should undergo PPCI to improve survival. (Class 1; LOE B-NR). For patients such as this one, a delayed or selective approach should be taken once the patient is stabilized. Early angiography should not be denied solely based on a comatose state, but it should be deferred if there are clear non-cardiac causes for the arrest or if the patient’s overall prognosis is futile. A is incorrect because recent evidence shows no benefit to “emergency” PPCI for stable patients without ST-elevation. C is incorrect because while we wait for stability, we don’t necessarily have a fixed 72-hour “mandatory” delay for the heart if ischemia is suspected. D is incorrect, as fibrinolysis is generally not indicated for post-arrest patients without clear STEMI and carries risks in a post-CPR setting due to potential trauma. The MIRACLE2 Score is a tool for neuroprognostication. It helps clinicians estimate the likelihood of a poor neurological outcome at 6 months. A high score suggests that the benefit of an invasive procedure may be outweighed by the severity of the brain injury. Components of MIRACLE2: M – Missed (unwitnessed) arrest I – Initial non-shockable rhythm R – Reactive pupils at ROSC A – Age (points increase significantly at >60 and >80) C – Rhythm change (e.g., VF to PEA) L – Low pH (pH < 7.20) E – Epinephrine (any dose given) Clinical Threshold: A score of >5 indicates a high risk of poor neurological recovery, which may lead a Heart Team to favor stabilization over immediate emergency angiography in patients without ST-elevation. Early recognition of STEMI in resuscitated patients and direct transfer to a PCI-capable center is associated with improved survival. Survival-to-hospital discharge in the patient who is comatose with out-of-hospital cardiac arrest is

On this bonus episode of ECG, the team discuss whether you skip dialogue when playing video games, or whether you read every inch of lore. Hosted on Acast. See acast.com/privacy for more information.

On this weeks episode of ECG, Guy is away getting surgery so Pugs steps up to chat memory cards, Chris makes a one-handed pack lunch and Ellie considers buying a robot dog!This is a Frank Podcast. Hosted on Acast. See acast.com/privacy for more information.

Metade de todas as mortes cardiovasculares do mundo é morte súbita por arritmia ventricular. E boa parte delas começa com um achado que você recebe toda semana no consultório: uma extrassístole ventricular no Holter. A pergunta que separa o inofensivo do fatal não está na extrassístole, está no que você olha antes dela.Neste episódio, Diandro Mota e Fernanda Justo recebem o Dr. Hugo Bellotti, eletrofisiologista formado no Dante Pazzanese e no InCor e hoje responsável pelo setor de eletrofisiologia invasiva do Dante Pazzanese. Um dos maiores nomes brasileiros em ablação de taquicardia ventricular, ele constrói aqui o raciocínio completo, da anamnese ao teste genético, do beta-bloqueador à punção epicárdica, com foco na realidade brasileira, incluindo o paciente chagásico.O ponto que derruba um hábito consolidado: "via de saída de VD" não é sinônimo de extrassístole benigna. O Dr. Hugo é direto ao dizer que extrassístoles capazes de deflagrar fibrilação ventricular podem sair de qualquer lugar, inclusive de lá. E traz o caso de uma paciente com apenas 1% de densidade, todas isoladas, que evoluiu para morte súbita abortada e hoje vive com CDI. O que a condenava não era a quantidade: era o acoplamento ultracurto caindo sobre o pico da onda T. Densidade tranquiliza, morfologia decide.Para quem é esse episódio Cardiologistas, arritmologistas, residentes e estudantes que recebem laudos de Holter com extrassístoles ventriculares e precisam decidir entre observar, medicar ou encaminhar para ablação.⏱️ Capítulos00:00 — Abertura e quem é o Dr. Hugo Bellotti02:08 — MEV Global 2026: desconto para ouvintes do DozeCast04:01 — Metade das mortes cardiovasculares é súbita07:57 — Os três pilares diante de uma extrassístole11:53 — O eletro antes do Holter: V1, plano frontal e repolarização13:30 — Acoplamento curto, R sobre T e o caso da paciente com CDI17:57 — Localizando o foco pelo ECG e o mito da via de saída de VD21:21 — Quantificação: 10%, 21% e por que o Holter oscila25:21 — Eco, ressonância, ergométrico, PET e teste genético30:15 — Quando tratar: fármacos, magnésio e a eficácia real34:13 — Ablação: sucesso, complicações e decisão compartilhada40:41 — Cardiopatia estrutural: isquêmico x não isquêmico43:37 — Chagas e a técnica brasileira de punção epicárdica53:43 — Mapeamento eletroanatômico e o atraso tecnológico do SUS01:05:49 — Mensagens finais do Dr. Hugo 

Rood & Riddle Equine Hospital is entering an exciting new chapter through a strategic partnership with Equine Care Group (ECG), bringing together two veterinarian-led organizations with a shared commitment to advancing equine medicine worldwide. In this special episode of StallSide, Dr. Deborah Spike-Pierce, CEO/President of Rood & Riddle, and Dr. Tom Mariën, CEO/Founder of Equine Care Group, talk about what the partnership means for Rood & Riddle, its clients and the broader equine community. The conversation explores the vision behind joining forces, the opportunities for greater collaboration in clinical care, research and education and how the partnership will help expand access to expertise and innovation across an international network. Most importantly, Rood & Riddle will continue to operate with the local leadership, clinical autonomy and commitment to exceptional equine care that have defined the practice for decades. Together, Rood & Riddle and ECG are building on their respective strengths while creating new opportunities to advance equine veterinary medicine for horses, clients and veterinary professionals around the world. Watch episodes on YouTube @roodandriddle or visit us at www.rrvp.com

Is your company's wellness programme addressing what employees actually need? Liezel van der Westhuizen explores Healthi and Clinics on Cloud, a technology-enabled corporate health screening solution that can assess more than 60 health parameters and help identify broader workforce wellness trends. Discover how data-informed employee wellness strategies could help organisations better target concerns around stress, burnout, cardiovascular health, diabetes risk, physical activity, nutrition and overall workplace wellbeing. Companies spend time and money on workplace wellness, but what if the programme being offered isn't addressing what employees actually need? Healthi is bringing a more data-driven approach to corporate wellness through Clinics on Cloud, a technology-enabled health screening solution capable of assessing more than 60 health parameters. From blood pressure, glucose and cholesterol to ECG, body composition, lung function, vision, hearing and mental wellbeing screening, the aim is to create a clearer picture of employee health and identify potential areas requiring attention. Fitness presenter, burnout and mental fitness coach Liezel van der Westhuizen joins Africa Melane on CapeTalk and Talk Radio 702 to unpack how health screening data could help organisations move beyond generic wellness initiatives and build more targeted employee wellbeing programmesSee omnystudio.com/listener for privacy information.

durée : 00:14:46 - Entendez-vous l'éco ? - par : Aliette Hovine - A l'heure de la rentrée scolaire, et quelques mois après les propos polémiques de Philippe Aghion sur les programme de SES, le professeur Emmanuel Martin nous explique comment sont construites, débattues et enseignées les sciences économiques et sociales au lycée. - équipe : Tina Iung, Noé Mignard - invités : Emmanuel Martin Professeur d'économie en prépa ECG et au lycée Vous aimez ce podcast ? Pour écouter tous les épisodes sans limite, rendez-vous sur Radio France

durée : 00:59:41 - Entendez-vous l'éco ? - par : Aliette Hovine - A l'aune du décès d'Edouard Balladur et du contexte présidentiel, retour sur le tournant libéral de 1986, et notamment sur l'étape de la financiarisation. Une discussion suivie d'une immersion, avec le professeur Emmanuel Martin, dans les classes de sciences économiques et sociales au lycée. - équipe : Tina Iung, Noé Mignard - invités : Fabien Eloire professeur des universités en sociologie et co-directeur de l'Institut des sciences sociales à l'université de Lille, Emmanuel Martin Professeur d'économie en prépa ECG et au lycée Vous aimez ce podcast ? Pour écouter tous les épisodes sans limite, rendez-vous sur Radio France

A 'broken heart' can look just like a heart attack, and now a new blood test may tell the difference. A broken heart isn't just an expression. Extreme emotional or physical stress can sometimes cause a genuine heart condition that looks remarkably like a heart attack. It's called Takotsubo syndrome, or 'broken heart syndrome', and it overwhelmingly affects women after menopause. Someone experiencing it may suddenly develop severe chest pain, an abnormal ECG and blood tests showing signs of heart injury. Even the heart's pumping ability can be affected. The problem is that these are also classic signs of a heart attack. The important difference is what's happening inside the heart. A typical heart attack involves a problem with blood flow through a coronary artery. With broken heart syndrome, part of the heart muscle temporarily stops contracting normally. Why knowing the difference matters: Doctors can't simply look at a woman with chest pain and decide that stress caused it, and missing a genuine heart attack could be deadly. So currently, many patients with suspected Takotsubo undergo coronary angiography, an invasive procedure in which a catheter is passed through an artery, usually from the wrist or groin, and dye is used to look for blockages in the coronary arteries. It's often only after doctors find no culprit blockage that Takotsubo becomes clear. That matters particularly for older women as 86-91 percent of the Takotsubo patients were women over 50. The researchers behind this new study identified the lack of a reliable early non-invasive tests and published their study in the European Heart Journal. They studied 3,615 patients who had either acute coronary syndrome or Takotsubo syndrome taking blood samples when patients arrived at hospital. They measured a range of substances in the blood associated with heart-muscle stress, inflammation, cholesterol, blood-vessel damage and the body's stress response. They then used machine learning to identify which combination was best at distinguishing Takotsubo from a conventional heart attack. The result was a five-part scoring system called BioTAK which combines biological sex with four blood measurements. One marker called sLOX-1, associated with blood-vessel changes and plaque disruption, was much higher in acute coronary syndrome. Another called PAM, involved in sympathetic nervous-system activity and anxiety regulation, was higher in Takotsubo. While the two conditions that can look almost identical from the outside the study showed they leave very different chemical fingerprints in the blood. The researchers then tested BioTAK on another 1,792 patients and found that it was able to accurately place almost 90% of patients into either a high- or low-probability group for Takotsubo before they underwent invasive angiography. BioTak could eventually give doctors another piece of information much earlier in the process, potentially helping some women with Takotsubo avoid an invasive procedure they didn't ultimately need. LISTEN ABOVESee omnystudio.com/listener for privacy information.

Medical AI is already getting good at doing things doctors do. Dr. Ziad Obermeyer thinks the bigger opportunity is using AI to discover things medicine doesn't yet know.His work shows both sides of that future: algorithms can amplify bad assumptions when trained on the wrong targets, but they can also uncover signals in medical data that humans miss. Obermeyer argues that as more health data is collected outside the hospital, AI could turn it into a continuous picture of health rather than a series of isolated snapshots.Free course: Improve your metabolic healthGet our free email course on how glucose, nutrition, exercise, sleep, and measurement can help you build habits that support better energy and long-term health: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://levels.link/wnl⁠What We Cover:Why AI should learn from patients and outcomes, not just doctorsHow an ECG model found hidden risk of sudden cardiac deathWhy medical data access is still a major bottleneckHow more measurement could actually mean fewer unnecessary testsWhy healthcare may be entering a “mainframe to PC” transition

Guest: Bruno Batinica, MD Earlier recognition of ATTR-CM remains a challenge, but emerging applications of AI could offer a new way to raise clinical suspicion. Dr. Bruno Batinica, a Postdoctoral Associate at the Yale School of Medicine, explores how AI models could identify patterns in ECG and echocardiography that may help flag patients for further evaluation.

The U.S. launches new strikes on Iran,  Germany formally blames Russia for an explosives-laden drone found at Leipzig Airport, the U.K.'s Starmer resigns as MP, Canada's Liberals sweep three federal byelections, a Bank of America vice president is killed in a Times Square stabbing, Trump commits $4 million to support conservative media in Europe, a whistleblower alleges that the U.S. Postal Service's new mail ballot system is flawed and untested, China punishes 10 people for sharing Tibet flood misinformation, the U.K. records its hottest summer since 1884, and a new AI system can reportedly detect heart failure via an ECG in under two seconds. Sources: Verity.News

ECG rhythms aren't random squiggles—they're the story of an electrical relay race inside the heart. In this episode of Ten Minute Medic, you'll follow the baton from the SA node to the Purkinje fibers and finally understand why P waves, PR intervals, narrow complexes, wide complexes, and heart blocks look the way they do. We'll cover what happens when the runner slows down, drops the baton, takes the scenic route, or starts an entirely separate race—because apparently even cardiac cells can ignore the chain of command. Stop memorizing rhythm strips and start following the electricity. Cardiac Conduction Review Guide

Medical disclaimer: The information shared on this podcast is for educational and informational purposes only. It is not intended as medical advice and should not be used as a substitute for professional guidance from a qualified healthcare provider. If you have questions about your health or a medical condition, please consult a licensed clinician who knows you and your history. This week on This Week in Heart Rate Variability, we open a new themed month by looking at where heart rate variability is headed next. Six studies map the future of the field — from a unifying theory of cardiovascular instability built on Shannon entropy, to the regulatory and technical realities of validating consumer wearables, to a meta-analysis quantifying how far photoplethysmography still is from true electrocardiography-derived HRV, to a virtual reality study, a forest-based multimodal field study, and a deep dive into the asymmetric structure of the heartbeat itself. RESEARCH HIGHLIGHTS THIS WEEK 1. Shannon Entropy in Heart Rate Variability: A Unified Indicator of Electrical and Hemodynamic Cardiovascular Instability PUBLICATION: Medical Research Archives AUTHORS: Orazio Antonio Barra KEY FINDING: This systematic review pooled 22 published studies that applied Shannon entropy of RR intervals to atrial fibrillation and tilt-induced syncope. Entropy declined progressively across both conditions — roughly ten percent at baseline instability, fifteen to twenty percent approaching pre-crisis, and twenty-five to thirty percent as crisis became imminent — with entropy showing better specificity than other HRV indices while holding onto its sensitivity. SIGNIFICANCE: Entropy looks less like a metric tied to one specific condition and more like a general-purpose marker of autonomic complexity loss that shows up consistently whether the underlying instability is electrical or hemodynamic. This is a synthesis of existing studies rather than a new trial, so it should be read as a strong, well-supported hypothesis rather than a validated bedside tool. Read the full study: https://esmed.org/MRA/mra/article/view/7606 2. Validity, Reliability, and Regulatory Considerations for Consumer Devices in Clinical Research Data Collection PUBLICATION: Applied Clinical Trials Online AUTHORS: Lauren Crooks, Greta Marie van Schoor, Anthony Everhart, Bill Byrom, and Thijs Sondag KEY FINDING: This article maps the validity, reliability, and regulatory landscape for consumer wearables used in decentralized clinical trials. Heart rate accuracy can approach ECG-level concordance under favorable conditions, but motion artifacts, device-to-device variation, and demographic performance gaps can cause aggregate agreement statistics to mask large individual-level errors. Only an estimated 11% of devices on the market have been rigorously and publicly validated. SIGNIFICANCE: Regulators are converging on "fit-for-purpose" validation rather than universal accuracy claims — asking whether a specific device is accurate enough for a specific clinical question, not whether it's accurate for everything. That's a useful discipline for anyone using consumer devices outside a formal trial, too. Read the full study: https://www.appliedclinicaltrialsonline.com/view/validity-reliability-regulatory-considerations-consumer-devices-clinical-research-data-collection 3. Accuracy of Photoplethysmography-Derived Pulse Rate Variability Compared with Electrocardiography-Derived Heart Rate Variability: A Systematic R...

An approach to chest pain, featuring the main life threatening conditions we don't want to miss - including typical features in the history and physical exam, ECG and recommended further investigations. PDFs available here: https://rhesusmedicine.com/products/assessment-or-interpretationConsider subscribing on YouTube (if you found any of the info useful!): https://www.youtube.com/channel/UCRks8wB6vgz0E7buP0L_5RQ?sub_confirmation=1Patreon: https://www.patreon.com/rhesusmedicineBuy Us A Coffee!: https://www.buymeacoffee.com/rhesusmedicineTimestamps:0:00 Chest Pain Introduction0:40 Acute Coronary Syndrome3:17 Tension Pneumothorax4:03 Pulmonary Embolism5:14 Cardiac Tamponade6:30 Aortic Dissection7:43 Esophageal Rupture8:34 Cardiac vs Non Cardiac Chest Pain (Other Causes of Chest Pain) LINK TO SOCIAL MEDIA: https://www.instagram.com/rhesusmedicine/Please remember this podcast and all content from Rhesus Medicine is meant for educational purposes only and should not be used as a guide to diagnose or to treat. Please consult a healthcare professional for medical advice. ReferencesBMJ Best Practice (2026) Assessment of chest pain – Differential diagnosis of symptoms. BMJ Publishing Group.Farkas, J. (2025) Approach to chest pain. EMCrit Project. Published 15 January 2025.McGill Journal of Medicine (n.d.) Approach to: Chest pain. McGill Journal of Medicine.Kendall, J.M. and Hancock, I. (2019) Chest Pain Syndromes. RCEMLearning EMFP. Published 16 July 2019.

In this episode of the Heart podcast, Digital Media Editor, Professor James Rudd, is joined by Dr Nick van Osta from Maastricht University. They discuss a review paper on computational modelling in cardiovascular disease. They cover the use of AI for: ECG diagnosis automatic ejection fraction segmentation from echocardiography prediction of success in cardiac resynchronisation therapy If you enjoy the show, please leave us a positive review wherever you get your podcasts. It helps us to reach more people - thanks! Link to published paper: "Individual hearts: computational models for improved management of cardiovascular disease" - https://heart.bmj.com/content/112/11/589  

Contributor: Aaron Lessen, MD Educational Pearls: Big question in cardiac arrest: is the rhythm shockable? Shockable: ventricular fibrillation (VF) and pulseless ventricular tachycardia Non-shockable: asystole and pulseless electrical activity (PEA) Rhythm classification is typically based on ECG, but echocardiography can directly visualize myocardial fibrillation Occult VF: a rhythm that appears non-shockable on ECG but demonstrates VF on echocardiography A 2025 multicenter prospective study looked at 811 patients with out-of-hospital cardiac arrest 5.3% had occult VF detected by echocardiography Of the patients with occult VF:  81.4% had PEA on ECG 18.6% had asystole on ECG Patients with occult VF were less likely to receive defibrillation because their ECG suggested a nonshockable rhythm Clinical takeaway: echocardiography during cardiac arrest may reveal a potentially shockable rhythm hiding behind an apparently nonshockable ECG This identifies a subset of cardiac arrest patients who would otherwise be managed as PEA or asystole based on ECG   References Gaspari R, Adhikari S, Gleeson T, Kapoor M, Lindsay R, Noble V, Nomura JT, Weekes A, Theodoro D. Occult Ventricular Fibrillation Visualized by Echocardiogram During Cardiac Arrest: A Retrospective Observational Study From the Real-Time Evaluation and Assessment for Sonography-Outcomes Network (REASON). J Am Coll Emerg Physicians Open. 2025 Jan 13;6(1):100028. doi: 10.1016/j.acepjo.2024.100028. PMID: 40012664; PMCID: PMC11853361.   Summarized by Meg Joyce, MS3 | Edited by Meg Joyce & Ahmed Abdel-Hafiz, NREMT-P   Donate: https://emergencymedicalminute.org/donate/  

How much time do you spend looking at a screen when you'd rather be making eye contact with your patient? In this MedAxiom HeartTalk, R. Kannan Mutharasan, MD, MBA, FACC, FAHA, cardiologist at Northwestern Medicine, shares how AI is helping clinicians stay focused on patients and uncover insights that could lead to earlier diagnoses. As the technology advances, the real work of realizing AI's potential in everyday cardiovascular care is just beginning.

Point-of-care ultrasound (POCUS) is rapidly transforming emergency medical services, stepping up as the modern equivalent of the 12-lead ECG for today's paramedics, according to Dr. Ross Prager. While portable ultrasound technology was initially developed to miniaturize heavy hospital equipment for field use, widespread adoption faced friction due to complex training demands and accuracy drop-offs in fast-paced environments. AI integration directly tackles these scaling bottlenecks by guiding real-time image acquisition and providing high-level diagnostic interpretation.   By automatically identifying critical structures like the pleural line or organ interfaces, AI helps paramedics capture crisp, reliable views—even under chaotic field conditions with severe glare, heat, or noise. For trauma and undifferentiated dyspnea calls, prehospital ultrasound delivers vital objective data. Detecting free abdominal fluid or absent lung sliding allows EMS teams to notify receiving trauma centers immediately. This clinical head start mobilizes blood banks, surgical staff, and operating rooms before the ambulance even arrives, cutting down critical time to definitive care.

“We started using AI to enhance algorithms and software to better be able to understand the data that’s in each patient’s ECG. And our goal with that was to bring forward personalized medicine in arrhythmia therapy and improve patient outcomes,” Vektor Medical CEO Rob Krummen says while discussing vMap. In this episode of the Vanguards of Healthcare podcast, Krummen sits down with Bloomberg Intelligence analyst Matt Henriksson to discuss the expansion of the vMap system, which uses standard 12-lead electrocardiogram (ECG) readings to help physicians treat arrhythmia cases, including atrial fibrillation. He also covers the company’s strategy to democratize electrophysiology and get patients to ablation treatment as early as possible.See omnystudio.com/listener for privacy information.

Chris thinks the team should come up with a video game, similar to that of Teeto, in hopes a developer hears the bones of the game and decides to throw their wallet at ECG. Hosted on Acast. See acast.com/privacy for more information.

In 11,409 adults with CKD and no prior heart failure, three standard ECG features independently predicted new-onset HF hospitalization. The findings support routine ECG as a low-cost adjunct to existing HF risk assessment in CKD.

Picture this. You're standing over a patient whose monitor is showing one of the most frightening rhythms in cardiology. Someone says, "It's complete heart block," and suddenly everyone's focused on the ECG. But here's the question that separates a technician from a clinician: Do you actually understand why it's happening? In this episode of Ten Minute Medic, we're going beyond memorizing P waves, QRS complexes, and AV dissociation. Instead, we're going to pull back the curtain on the heart's electrical system and discover why third-degree heart block is actually one of the most logical rhythms in medicine. Once you understand the physiology, you'll never have to memorize this rhythm again—you'll be able to predict it, explain it, and, most importantly, recognize what it means for your patient. So, if you're ready to stop chasing rhythm strips and start understanding the story they're telling, let's jump in. Third Degree Heart Block Study Guide

On today's bonus episode of ECG, long time listener Shon poses the question; “what video game character would you NOT want to bump into on holiday? Hosted on Acast. See acast.com/privacy for more information.

On this week's episode of ECG, we share some exciting news about a new video game... featuring us! Well, our voices...Pugs is back and wants to know how you'd make a cocktail based off a video game character, and Chris delivers some hilarious anecdotes. Hosted on Acast. See acast.com/privacy for more information.

In this month's EM Quick Hits Podcast, Amna Karabegovic joins us for an EMC² case of pediatric altered LOA and neurocritical care, Anand Swaminathan simplifies the high-risk management of pulmonary hypertension and right ventricular failure, and Brit Long reviews how to recognize and treat Cytokine Release Syndrome. Plus, Andrew Tagg on whether uncomplicated pediatric distal radius fractures need reduction, Jesse McLaren on a systematic approach to ECG interpretation in the bradycardic patient, and Sara Gray and Katie Lin return for Part 2 of “Coaching the EM Mind,” with practical strategies for managing stress and optimizing psychological safety on shift… Please consider a donation to ensure EM Cases continues to be high quality Free Open Access Medical Education here: https://emergencymedicinecases.com/donation/

On Today's bonus episode of ECG, Ellie asks the question; "What are some old games you never played back in the day, but have played recently and are now like ohhhh I get it now" Hosted on Acast. See acast.com/privacy for more information.

On this week's episode of ECG, Ellie is amazed by her fiancé's latest Pokemon card purchase, Guy teases us with more DND planning, and Chris is fuming about the team's professionalism. Hosted on Acast. See acast.com/privacy for more information.

On today's bonus episode of ECG, the Gang bring more gaming-based "Would You Rather" questions, and discover something shocking about Guy... Hosted on Acast. See acast.com/privacy for more information.

June News You Can Use Healthcare 2026: Stranger Than Fiction, Funnier Than It Should Be The discussion includes the ADA inadvertently demonstrated the Streisand Effect by censoring its own published editorial, turning a minor issue into a major news story; Millions are losing ACA coverage, while legal loopholes allow some emergency rooms to refuse patients unable to pay upfront; AI-powered ECG analysis is uncovering hidden signs of heart disease, proving AI can augment, not replace clinicians; A high-profile dispute between OpenAI and OpenEvidence reminds us that even peer-reviewed research deserves critical scrutiny; And because healthcare is never boring, a French emergency department ended up calling the bomb squad over a World War I artillery shell in an unforgettable place. To stream our Station live 24/7 visit www.HealthcareNOWRadio.com or ask your Smart Device to “….Play Healthcare NOW Radio”. Find all of our network podcasts on your favorite podcast platforms and be sure to subscribe and like us. Learn more at www.healthcarenowradio.com/listen

On this weeks episode of ECG, Pugs is in and creates a grunge band using video game characters, Chris starts an argument with Guy around movie characters, and the team discuss Sony's move to get rid of physical media. Hosted on Acast. See acast.com/privacy for more information.

On today's bonus episode of ECG, the gang discuss gaming and dating, and discover one member of the team has an interesting kink… Hosted on Acast. See acast.com/privacy for more information.

On this week's episode of ECG, Pugs tags in for a sick Ellie and talks Croc, Guy allows himself to get excited for GTA6 and Chris asks whether the audience cares about Pokemon cards. Hosted on Acast. See acast.com/privacy for more information.

Welcome back to July's Papers of the Month. This month we've got three papers that tackle some of the biggest questions we face in emergency and critical care medicine. They're all very different studies, but each one looks at an intervention that many of us use, or at least think about, on a regular basis. First up, we look at ARISE FLUIDS, a major trial examining one of the longest-running debates in sepsis care. Should we be reaching for fluids or vasopressors first in septic shock? We've spent years worrying about giving too much fluid, and equally worrying about starting vasopressors too early. This study gives us some of the best evidence yet about what happens when we take a more restrictive fluid approach and start vasopressors earlier. Next, we move to cardiac arrest and the BIHCA trial, looking at sodium bicarbonate during in-hospital cardiac arrest. Despite guideline recommendations and a lack of convincing evidence, bicarbonate continues to be used in many arrests around the world. This study finally gives us some high-quality data on whether it's actually helping our patients. And finally, we head back to the ECG with a fascinating paper looking at the lead V5 T-wave to R-wave ratio as a marker of right ventricular dysfunction in pulmonary embolism. It won't change practice tomorrow, but it raises some interesting questions about what the ECG may still have to tell us about risk stratification in PE. So let's get into it! Once again we'd love to hear any thoughts or feedback either on the website or via X @TheResusRoom! Simon & Rob

Listener feedback on valvular heart disease, statins and frailty, left atrial posterior wall ablation fails again, interpreting medical tests and AI ECG reading are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Listener Feedback PREVUE-VALVE Study https://www.jacc.org/doi/10.1016/j.jacc.2026.02.5137 II Statins and Frailty Statin Initiation Tied to Lower Frailty Risk in Older Adults https://www.medscape.com/viewarticle/statin-initiation-tied-lower-frailty-risk-older-adults-2026a1000lec Statins and Survival Free of Incident Frailty  https://doi.org/10.1093/eurheartj/ehag451 III LA Posterior Wall Isolation Fails Again CORNERSTONE Trial https://doi.org/10.1093/eurheartj/ehag486 CAPLA Trial https://jamanetwork.com/journals/jama/fullarticle/2800186 IV Does the Display of Test Results Improve Clinical Decisions? Interval Likelihood Ratios for Clinical Decsion-Making https://evidence.nejm.org/doi/full/10.1056/EVIDoa2500249 Making Sense of Health Statistics https://journals.sagepub.com/doi/full/10.1111/j.1539-6053.2008.00033.x V AI and the ECG and Saving Doctors Case Report — AI-Enhanced Diagnostics https://www.nature.com/articles/s41591-026-04454-y The New York Times article https://www.nytimes.com/2026/06/22/health/artificial-intelligence-heart-damage.html You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net

This episode is part of our comprehensive Decipher the Guidelines Series covering the 2025 ACC/AHA/ACEP/NAEMSP/SCAI Guideline for the Management of Patients With Acute Coronary Syndromes.  The following question refers to Section 5.2.1 of the 2025 ACS Guidelines. The question is asked by Thomas Jefferson medical student and CardioNerds Academy Intern Dr. Grace Qiu, answered first by Henry Ford Interventional cardiology fellow and member of the CardioNerds Interventional Cardiology Council Dr. Li Pang, and then by expert faculty Dr. Michelle O'Donoghue. Dr. O'Donoghue is a cardiologist, senior investigator with the TIMI Study Group, and Associate Professor of Medicine at Harvard Medical School who holds the McGillycuddy-Logue Endowed Chair in Cardiology at Brigham and Women's Hospital. She was the Vice Chair of the Writing Committee for the 2025 ACS Guidelines. Question #2 A 63-year-old woman presented to the emergency room for chest pain. She described having exertional chest pain for the past two months and had an episode of severe pain after dinner 3 days ago. She went to bed and slept it off.  She told her children today at a family gathering, and was immediately brought to the ED by her daughter. She has a history of hypertension and hyperlipidemia. She was asymptomatic and normotensive in the ED. Labs show a down-trending troponin and an elevated NT-proBNP but are otherwise unremarkable. Her ECG showed Q waves with ST elevation in V2-V4. She was treated with aspirin and heparin drip, and taken to the cath lab. Coronary angiogram showed complete proximal LAD occlusion with right-to-left collaterals, without significant residual disease elsewhere. She remains asymptomatic and is stable, both hemodynamically and electrically. What is the next best step with regard to reperfusion and anti-thrombotic management? A Proceed with primary PCI to LAD  B Medical management with aspirin and enoxaparin  C Medical management with aspirin and clopidogrel D Medical management with aspirin and ticagrelor   Answer #2 Explanation  The Correct answer is D In patients who are stable with STEMI and have a totally occluded infarct-related artery >24 hours after symptom onset and are without evidence of ongoing ischemia, acute severe HF, or life-threatening arrhythmia, PPCI should not be performed due to lack of benefit. (Class 3, LOE B-R) The benefit of PPCI begins to diminish after >12 hours from symptom onset, but there appears to be continued benefit through approximately 24 hours.  In stable asymptomatic patients with an occluded artery >48 hours after symptom onset, routine PCI has not been shown to be beneficial in the absence of ongoing ischemia. The relative utility of routine PCI for asymptomatic patients with STEMI between 24 and 48 hours from symptom onset is less rigorously tested. PCI is not recommended for an occluded infarct-related artery if the patient is asymptomatic and has a completed infarct. MACE outcomes were similar in those with an occluded infarct-related artery who underwent medical therapy versus those who underwent PCI 3 to 28 days after an MI (Occluded Artery Trial [OAT]), and results were no different at 7-year follow-up. Similar findings were noted in the DECOPI (Desobstruction Coronaire en Post-Infarctus) trial, which enrolled patients with an occluded artery and Q waves on the ECG presenting 2 to 15 days after symptom onset. However, coronary revascularization should be considered for patients with late presentations with continued signs and symptoms of ischemia, including cardiogenic shock, acute severe HF, persistent angina, and life-threatening arrhythmias.  Main Takeaway In patients who are stable with STEMI who have a totally occluded infarct-related artery >24 hours after symptom onset and are without evidence of ongoing ischemia, acute severe HF, or life-threatening arrhythmia, PPCI should not be performed due to lack of benefit. Guideline Loc. Section 5.2.1 

#237: University of Pittsburgh & Dell Technologies: Can AI Wearables Predict a Heart Attack Before It Strikes?What if your wearable could do more than track steps - and actually help detect cardiovascular risk before symptoms appear?Heart disease is the deadliest disease on the planet. In the U.S. alone it killed close to 300,000 - more than cancer. And it's a quiet killer: by the time you feel a symptom, the damage is usually already done.Pengfei Zhou, Assistant Professor at the University of Pittsburgh's School of Computing and Information, is trying to catch it earlier - building AI-powered wearables that read your heart continuously instead of waiting for a checkup.That tracks with something deeper for me: my brother-in-law is a spinal surgeon, and a book called Outlive got him thinking about the “four horsemen” of disease. Heart disease topped the list. He's been mostly plant-based ever since.I sat down virtually with Pengfei, Matt de Lima Barbosa (Director of IT, Pitt's School of Computing and Information), and Adrienne Garber, Chief Technology & Innovation Strategist for Higher Education at Dell Technologies, to talk about their partnership. What emerged is a live case study in what happens when a researcher, an embedded IT team, and a technology partner actually commit to the same problem instead of working around each other.Welcome to episode 237!GuestsPengfei Zhou, Assistant Professor, University of Pittsburgh School of Computing and InformationMatt de Lima Barbosa, Director of Information Technology, University of Pittsburgh School of Computing and InformationAdrienne Garber, Chief Technology & Innovation Strategist, Higher Ed, Dell TechnologiesTimestamps(01:00) Inside Pitt's School of Computing and Information(02:45) Pengfei Zhou's teaching and research focus(03:53) AIoT, wearables, and heart monitoring(07:04) How Dell's higher ed innovation pilot reached Pitt(10:41) Why localized AI matters for health data(12:18) How embedded IT helps researchers move faster(13:41) Dell's role as connective tissue between researchers and IT(18:18) Combining PPG and ECG signals for better blood pressure monitoring(21:00) The “Who Not How” Moment: Helping researchers move faster(25:12) AI, deep learning, and solving real problemsListen now: YouTube x Apple x SpotifyWhenever you're ready, there are 3 ways you can connect with TechTables:1.

What We CoveredWhat if your wearable could do more than track steps — and actually help detect cardiovascular risk before symptoms appear?In this episode, Joe talks with University of Pittsburgh's Pengfei Zhou & Matt de Lima Barbosa, along with Dell Technologies' Adrienne Garber, about how AI, edge computing, and wearable devices are shaping the future of heart monitoring.01 Why wearables are the next frontier for heart health: how real-time sensor data from everyday devices could detect cardiovascular risk before symptoms ever appear.02 What AIoT actually means in practice: how Pengfei's research combines AI and connected sensors to build deep learning models that go far beyond step counting.03The role of embedded IT in research speed: how Matt's team connects faculty to secure infrastructure and technical support so researchers can move faster and focus on the science.04 How Dell is partnering with higher ed researchers: why Adrienne's team invests in university innovation programs — and what that looks like when it reaches researchers working on real health problems.05 Why localized AI wins on speed, privacy, and personalization: the case for keeping AI processing at the edge instead of sending sensitive health data to the cloud.06 What the future of higher ed innovation actually requires: why the collaboration between researchers, IT, and technology partners like Dell is the ingredient most people overlook. FeaturingPengfei Zhou, Assistant Professor, University of Pittsburgh School of Computing and InformationMatt de Lima Barbosa, Director of Information Technology, University of Pittsburgh School of Computing and InformationAdrienne Garber, Chief Technology & Innovation Strategist, Higher Ed, Dell Technologies Timestamps(01:00) Inside Pitt's School of Computing and Information(02:45) Pengfei Zhou's teaching and research focus(03:53) AIoT, wearables, and heart monitoring(07:04) How Dell's higher ed innovation pilot reached Pitt(10:41) Why localized AI matters for health data(12:18) How embedded IT helps researchers move faster(13:41) Dell's role as connective tissue between researchers and IT(18:18) Combining PPG and ECG signals for better blood pressure monitoring(21:00) The “Who Not How” Moment: Helping researchers move faster(25:12) AI, deep learning, and solving real problemsListen now: YouTube x Apple x SpotifyWhenever you're ready, there are 3 ways you can connect with TechTables:1.

CardioNerds (Amit and Dan), Billy Joe Mullinax, and Saahil Jumkhawala discuss the long term management of pulmonary embolism with Dr. Soophia Naydenov.  The episode focuses on the approach to patients who struggle with persistent symptoms like dyspnea and fatigue even after completing the acute phase of anticoagulation. This spectrum of disease, ranging from mild post-PE impairment to chronic thromboembolic pulmonary hypertension (CTEPH), requires a structured follow-up. The discussion covers the critical importance of identifying CTEPH early, the necessary timelines for follow-up, and the appropriate objective screening tools and invasive testing to guide patient care toward full functional recovery. Audio editing by CardioNerds academy intern, Grace Qiu. Dr. Dinu Balanescu and Dr. Billy-Joe Mullinax are Co-chairs for the CardioNerds PE Series, developed in collaboration with the PERT Consortium.   Enjoy this Circulation 2022 Paths to Discovery article to learn about the CardioNerds story, mission, and values. CardioNerds Pulmonary Embolism PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Acronyms PE: Pulmonary Embolism PERT: Pulmonary Embolism Response Team CTEPH: Chronic Thromboembolic Pulmonary Hypertension QL: Quality of Life VTE: Venous Thromboembolism DASH: D-dimer, Age, Sex, History of non-provoked PE (a risk score) CPET: Cardiopulmonary Exercise Testing PFTs: Pulmonary Function Tests VQ Scan: Ventilation-Perfusion Scan DOACs: Direct Oral Anticoagulants TPA: Tissue Plasminogen Activator (Thrombolytics) ECMO: Extracorporeal Membrane Oxygenation Pearls: Post-PE “Syndrome” is a Spectrum: It is more accurately a spectrum of disease (sequelae of PE) rather than a single syndrome, ranging from mild fatigue/dyspnea to the most severe form, CTEPH. Structured Follow-up is Mandatory: All PE survivors need a structured follow-up, typically with checkpoints at 3, 6, 12, and 16–24 months, with the primary goal being to detect CTEPH, the deadliest, yet potentially curable, disease on the spectrum. Screening Should Be Objective and Practical: When screening for persistent symptoms, use objective assessment tools like the Post-VTE Functional Status (PVFS) scale or the Modified Medical Research Council (MMR-C) scale, as highly comprehensive but cumbersome tools (like the PE Quality of Life questionnaire) may not be practical for routine clinical use. Recurrence Risk Scores Aid in Anticoagulation Duration: Simple scores like the DASH score or the HERDO2 score (for women) can provide guidance when considering the continuation versus discontinuation of anticoagulation after the initial treatment phase. Invasive Testing for Persistent Symptoms: If a patient remains symptomatic at the 6-month mark despite normal non-invasive testing (chest X-ray, ECG, PFTs, six-minute walk, echo, VQ scan, CPET), consider invasive testing such as Right Heart Catheterization (RHC) at rest or with exercise, or an invasive CPET. Notes: Notes drafted by Saahil Jumkhawala. 1. The Spectrum of Post-PE Disease The term “post-PE syndrome” should be used with caution, as it refers to a spectrum of disease rather than a single entity. This spectrum includes symptoms (sequelae) that exist in a patient’s life following an incidental PE event that they did not have before. On one extreme is Chronic Thromboembolic Pulmonary Hypertension (CTEPH): The definition is clear, but it is the most deadly type, though thankfully rare (2% to 4%). It involves a residual clot and pulmonary hypertension identifiable at rest. In the middle is Chronic Thromboembolic Disease (CTED): Patients may have residual defects seen on a VQ or CT scan, but they do not have pulmonary hypertension. On the other side is a milder disease, which can include fatigue, dyspnea, or a patient’s perceived impairment, where the definitions of CTEPH and CTED are not met, but the patient remains symptomatic. 2. Structured Follow-up and Screening for Post-PE Symptoms Structured follow-up is key for all PE survivors, though the structure may vary based on available resources (PCP, Cardiology, Pulmonary, or multidisciplinary clinic). Recommended Timeline for Follow-up: Data from studies like ELOPE and FOCUS suggest checkpoints at 3, 6, 12, and up to 16 to 24 months. This timeline is designed to identify patients who may develop CTEPH. 88% of patients who develop CTEPH will be identified within about a year. A structured follow-up can reduce the delay in CTEPH diagnosis from 10–12 months to 4–6 months. Personal Practice Note: A quick 2–3 week/30-day check-in is recommended for severely ill patients (e.g., those who had TPA, profound shock, or ECMO support) to ensure medication compliance, manage symptoms, and identify red flags. Screening Tools (Objective Assessment): The first step is an inventory of patient symptoms, leaning toward objective rather than subjective assessment. Recommended Simple Tools: Modified Medical Research Council (MMR-C) for dyspnea evaluation. Post-VTE Functional Status (PVFS) scale. The Pulmonary Embolism Quality of Life (QL) questionnaire is comprehensive but long, making it tedious and better suited for research. Future Utility: Technology (AI/electronic tools) may assist in administering these questionnaires before the clinic visit, presenting the information as a “dashboard” for the provider. 3. Management of Persistent Symptoms and Further Testing Initial Non-Invasive Tests (Often done at 3 months): Echocardiogram VQ Scan Full PFTs Six-minute walk CPET Further Evaluation for Persistent Symptoms (e.g., at 6 months): If non-invasive tests (Chest X-ray, ECG, CPET) are normal but symptoms persist, more invasive testing should be considered as the patient has not returned to baseline. Repeat VQ scan or echocardiogram if symptoms have changed. Right Heart Catheterization (RHC) at rest or with exercise. Invasive CPET. PA gram (Pulmonary Angiogram) to assess vasculature. 4. Recurrence Risk and Anticoagulation Duration The decision to continue or discontinue anticoagulation depends on the patient’s risk factors, the situation of the PE (provoked or unprovoked), presence of active cancer, and patient preference. Recurrence Risk Scores: Simple scores are preferred for practicality. DASH Score. HERDO2 Score (particularly for women). The Vienna Score can be considered if the question is whether to restart anticoagulation after a disruption. Role of D-dimer in Abbreviation: While D-dimer can be used to guide the decision to restart anticoagulation after a planned pause (if D-dimer is high, resume), patient symptoms are preferable to guide management decisions like early abbreviation. 5. Prevention of Post-PE Syndrome Currently, there is no clear tool known to prevent the post-PE syndrome/spectrum of disease. Best Current Advice for Prevention/Recovery: Anticoagulation compliance. Pulmonary rehabilitation, which aids in faster recovery. General precautions, such as smoking cessation and body weight management. Future Research: Ongoing trials are investigating whether acute management strategies (e.g., using thrombolytics in intermediate-risk PE) can prevent long-term sequelae. (The PYTHO trial did not show a reduced rate of CTEPH in intermediate-risk PE patients who received thrombolytics). References: Khan, F., Tritschler, T., Kahn, S. R., & Rodger, M. A. “Venous Thromboembolism.” The Lancet, vol. 398, no. 10294, 2021, pp. 64-77. doi:10.1016/S0140-6736(20)32658-1. Kearon, C., & Kahn, S. R. “Long-Term Treatment of Venous Thromboembolism.” Blood, vol. 135, no. 5, 2020, pp. 317-325. doi:10.1182/blood.2019002364. Kahn, S. R., & de Wit, K. “Pulmonary Embolism.” The New England Journal of Medicine, vol. 387, no. 1, 2022, pp. 45-57. doi:10.1056/NEJMcp2116489. Di Nisio, M., van Es, N., & Büller, H. R. “Deep Vein Thrombosis and Pulmonary Embolism.” The Lancet, vol. 388, no. 10063, 2016, pp. 3060-3073. doi:10.1016/S0140-6736(16)30514-1. Chopard, R., Albertsen, I. E., & Piazza, G. “Diagnosis and Treatment of Lower Extremity Venous Thromboembolism: A Review.” JAMA, vol. 324, no. 17, 2020, pp. 1765-1776. doi:10.1001/jama.2020.17272.

Tim Mages is the CEO of ECG, expansion capital group,  where he helps businesses secure customized financing solutions to support growth, operations, and long-term success. With extensive experience in commercial finance and equipment leasing, Tim works closely with companies across a variety of industries to structure funding solutions tailored to their specific needs. Under his leadership, ECG has built a strong reputation for providing flexible financing options and helping businesses navigate complex funding challenges efficiently. Tim brings a practical and relationship-driven perspective to business lending, capital access, and strategic financing. Tim's perspective would be especially valuable for conversations around commercial finance, equipment leasing, business growth strategies, and how companies can better position themselves to access capital in today's market. During the show we discuss: Why traditional banks reject so many small business owners (and what they're really looking for) How alternative lenders evaluate risk differently—and why that opens more doors The biggest mistakes entrepreneurs make when trying to secure funding How to position your business to get approved faster and for higher amounts Why speed and flexibility in funding can be a competitive advantage The truth about merchant cash advances, equipment financing, and other options—what's legit and what's misunderstood How lenders think about cash flow vs. credit scores What it really takes to scale using capital without putting your business at risk Resources: Website: https://www.ecg.com/ LinkedIn: https://www.linkedin.com/in/tim-m-1647775/

My cardiologist ran a full cardiac workup (MRI, stress test, ambulatory ECG, labs) and told me I was perfectly healthy. I was 40 lbs overweight, insulin-resistant, nutritionally deficient, and running on 2–4 hours of sleep. Everything was "normal." Nothing was fine. ▶ FREE email course: the exact steps I used to go from dysfunction toward resilient health (no cost, straight to your inbox): https://medgeeks.co/get-started/metabolic-health/ If you're a clinician, this one's for you. You read labs all day, but nobody is reading yours. And "normal" labs can hide a metabolism that's quietly drifting years before any diagnosis shows up. In this video, I break down the gap between what your bloodwork flags and what your body is actually doing; why conventional medicine is built to catch disease but not dysfunction, why the reference range fails you, and what it actually takes to move toward what I call resilient health. We cover insulin resistance, the reference range problem, cellular metabolism, an autoimmune marker (ANA) that turned negative once I fixed the underlying environment, and the full spectrum from dysfunction to disease-free to resilient health.