Podcasts about on the frontlines of multiple sclerosis

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Andrew Chan, MD Increasing evidence indicates the involvement of B cells in the pathogenesis of multiple sclerosis (MS), but their exact role is unclear. Despite that uncertainty, B-cell depletion therapies have shown to ease symptoms, prevent relapses, and even slow the course of the disease. So how exactly do B-cell therapies work, and how do we know if they're right for our patients? Joining Dr. Charles Turck to talk about the role of b-cell therapies for our MS patients is Dr. Andrew Chan.

Host: Jennifer Caudle, DO Guest: Vikram V. Bhise, MD Pediatric multiple sclerosis (MS) occurs in more than 8,000 children in the United States alone, but there's little data regarding these patients' quality of life. That's why Dr. Vikram Bhise recently conducted research to gain a better understanding of pediatric MS patients' quality of life as they transition into adulthood. And now, Dr. Bhise joins Dr. Jennifer Caudle to share the results that were presented at the 2021 Consortium of Multiple Sclerosis Centers (CMSC) Annual Meeting.

Host: Jennifer Caudle, DO Guest: Vikram V. Bhise, MD Pediatric multiple sclerosis (MS) occurs in more than 8,000 children in the United States alone, but there's little data regarding these patients' quality of life. That's why Dr. Vikram Bhise recently conducted research to gain a better understanding of pediatric MS patients' quality of life as they transition into adulthood. And now, Dr. Bhise joins Dr. Jennifer Caudle to share the results that were presented at the 2021 Consortium of Multiple Sclerosis Centers (CMSC) Annual Meeting.

Guest: Patty Bobryk, MHS, PT, MSCS, ATP A multidisciplinary approach to multiple sclerosis (MS) is becoming more and more integral in practice as research continues to emerge on its significance. That's why physical therapist Ms. Patty Bobryk is here to debrief us on some highlights from the rehabilitation track at the 2021 Consortium of Multiple Sclerosis Centers (CMSC) that focused on collaborative care.

Guest: Patty Bobryk, MHS, PT, MSCS, ATP A multidisciplinary approach to multiple sclerosis (MS) is becoming more and more integral in practice as research continues to emerge on its significance. That's why physical therapist Ms. Patty Bobryk is here to debrief us on some highlights from the rehabilitation track at the 2021 Consortium of Multiple Sclerosis Centers (CMSC) that focused on collaborative care.

Guest: Ann D. Bass, MD Guest: Barry A. Singer, MD Multiple sclerosis is a chronic inflammatory and neurodegenerative disease with a highly variable clinical course.1,2 Most patients who have relapsing-remitting multiple sclerosis (RRMS) will eventually transition to a secondary progressive course (SPMS).3 Patients with SPMS may live with significant impairment in physical and cognitive functions.4 Early identification of disease progression is important.2 Join Dr. Barry Singer from the MS Center for Innovations in Care at the Missouri Baptist Medical Center in St Louis, Missouri as well as Dr. Ann Bass from the Neurology Center of San Antonio in San Antonio, Texas as they share their real-world clinical perspectives on the management of patients with more progressed RMS, including those with aSPMS, and MAYZENT as a treatment option. Together, they will explore the following decision points: How to actively identify first signs of RMS progression A therapy for progressing RMS, including active SPMS What to consider when getting patients started on MAYZENT, a disease-modifying treatment

Host: Jerome Lisk, MD Guest: Shivashankar Othy, DVM, PhD Despite the high prevalence of multiple sclerosis (MS), there's still a lot we don't know about this disease. One such area of uncertainty is in regard to how MS causes the immune system to become dysfunctional, but this knowledge is key as it could help us develop new treatment options. And now, we might be one step closer to discovering those treatments thanks to a recent study exploring specific T cells, and joining Dr. Jerome Lisk to discuss that study is Dr. Shiva Othy, a Project Scientist in the Department of Physiology and Biophysics at the University of California Irvine School of Medicine.

Host: David Weisman, MD Guest: Adil Javed, MD PhD How can providers help mitigate the symptoms of a disease as debilitating as multiple sclerosis? Dr. David Weisman examines management strategies for patients with multiple sclerosis with is Dr. Adil Javed, a board-certified neurologist and an Associate Professor of Neurology at the University of Chicago.

Host: Paul Doghramji, MD Guest: Pavle Repovic, MD, PhD There is no cure for relapsing multiple sclerosis (MS), a chronic and progressive disease in which disability accumulates over time, but available therapies may help modify the course by reducing disease activity. The MS specialist, Dr. Pavle Repovic, discusses KESIMPTA®, a treatment option offering adult RMS patients powerful efficacy with a demonstrated safety profile and flexible self-administration. 9/20 T-KSM-1393526

Host: Paul Doghramji, MD Guest: Pavle Repovic, MD, PhD There is no cure for relapsing multiple sclerosis (MS), a chronic and progressive disease in which disability accumulates over time, but available therapies may help modify the course by reducing disease activity. The MS specialist, Dr. Pavle Repovic, discusses KESIMPTA®, a treatment option offering adult RMS patients powerful efficacy with a demonstrated safety profile and flexible self-administration. 9/20 T-KSM-1393526

Guest: Timothy William West, MD Here to discuss staying ahead of progression in patients with relapsing multiple sclerosis (RMS) is Dr. Timothy William West. Dr. West walks us through pathophysiological changes in progressing RMS patients, a patient case demonstrating why patients may experience increasing disability, and key data on MAYZENT®(siponimod), the first and only oral disease-modifying therapy studied and proven to delay disability progression in a more progressed RMS patient population, including active SPMS. MAYZENT was evaluated in EXPAND—the largest Phase III study of secondary progressive MS (SPMS) patients to date (N=1651), which included a broad range of patients with moderate-to-advanced disability. Dr. West discusses clinical data from EXPAND including data of up to 5 years from a preplanned interim analysis of the EXPAND open-label extension study.

Guest: Timothy William West, MD Here to discuss staying ahead of progression in patients with relapsing multiple sclerosis (RMS) is Dr. Timothy William West. Dr. West walks us through pathophysiological changes in progressing RMS patients, a patient case demonstrating why patients may experience increasing disability, and key data on MAYZENT®(siponimod), the first and only oral disease-modifying therapy studied and proven to delay disability progression in a more progressed RMS patient population, including active SPMS. MAYZENT was evaluated in EXPAND—the largest Phase III study of secondary progressive MS (SPMS) patients to date (N=1651), which included a broad range of patients with moderate-to-advanced disability. Dr. West discusses clinical data from EXPAND including data of up to 5 years from a preplanned interim analysis of the EXPAND open-label extension study.

Guest: Timothy William West, MD Here to discuss staying ahead of progression in patients with relapsing multiple sclerosis (RMS) is Dr. Timothy William West. Dr. West walks us through pathophysiological changes in progressing RMS patients, a patient case demonstrating why patients may experience increasing disability, and key data on MAYZENT®(siponimod), the first and only oral disease-modifying therapy studied and proven to delay disability progression in a more progressed RMS patient population, including active SPMS. MAYZENT was evaluated in EXPAND—the largest Phase III study of secondary progressive MS (SPMS) patients to date (N=1651), which included a broad range of patients with moderate-to-advanced disability. Dr. West discusses clinical data from EXPAND including data of up to 5 years from a preplanned interim analysis of the EXPAND open-label extension study.

Host: Matt Birnholz, MD Guest: Maria K. Houtchens, MD Guest: Maria Lopes, MD Patients with multiple sclerosis (MS) are increasingly choosing to start families. It is incumbent on us as healthcare professionals to try to ensure their chances for healthy pregnancies while maintaining adequate disease control. In this program, Dr. Houtchens and Dr. Lopes discuss the importance of patient/healthcare provider partnerships in family planning. Specific points of focus include the role of effective contraception, key concepts regarding the use of disease modifying therapies, and important practical considerations related to patient care in the time before, during, and after pregnancy. EMD Serono is a business of Merck KGaA, Darmstadt, Germany. ©EMD Serono, Inc. All rights reserved. US/NPR/1019/0558a

Host: Matt Birnholz, MD Guest: Maria K. Houtchens, MD Guest: Maria Lopes, MD Patients with multiple sclerosis (MS) are increasingly choosing to start families. It is incumbent on us as healthcare professionals to try to ensure their chances for healthy pregnancies while maintaining adequate disease control. In this program, Dr. Houtchens and Dr. Lopes discuss the importance of patient/healthcare provider partnerships in family planning. Specific points of focus include the role of effective contraception, key concepts regarding the use of disease modifying therapies, and important practical considerations related to patient care in the time before, during, and after pregnancy. EMD Serono is a business of Merck KGaA, Darmstadt, Germany. ©EMD Serono, Inc. All rights reserved. US/NPR/1019/0558a

Host: Matt Birnholz, MD Guest: Maria K. Houtchens, MD Guest: Maria Lopes, MD Patients with multiple sclerosis (MS) are increasingly choosing to start families. It is incumbent on us as healthcare professionals to try to ensure their chances for healthy pregnancies while maintaining adequate disease control. In this program, Dr. Houtchens and Dr. Lopes discuss the importance of patient/healthcare provider partnerships in family planning. Specific points of focus include the role of effective contraception, key concepts regarding the use of disease modifying therapies, and important practical considerations related to patient care in the time before, during, and after pregnancy. EMD Serono is a business of Merck KGaA, Darmstadt, Germany. ©EMD Serono, Inc. All rights reserved. US/NPR/1019/0558a

Host: Matt Birnholz, MD Guest: Maria K. Houtchens, MD Guest: Maria Lopes, MD Patients with multiple sclerosis (MS) are increasingly choosing to start families. It is incumbent on us as healthcare professionals to try to ensure their chances for healthy pregnancies while maintaining adequate disease control. In this program, Dr. Houtchens and Dr. Lopes discuss the importance of patient/healthcare provider partnerships in family planning. Specific points of focus include the role of effective contraception, key concepts regarding the use of disease modifying therapies, and important practical considerations related to patient care in the time before, during, and after pregnancy. EMD Serono is a business of Merck KGaA, Darmstadt, Germany. ©EMD Serono, Inc. All rights reserved. US/NPR/1019/0558a

Host: Jennifer Caudle, DO Guest: Riley Bove, MD Guest: Bianca Weinstock-Guttman, MD The disease course of multiple sclerosis (MS) can take many paths based on numerous factors, including age at diagnosis, gender, and MS subtype. Layered upon the typical MS management challenges are those that can occur with the physical and physiological changes of the normal aging process. How might the care of a patient with MS need to be modified as they age? In this discussion, Dr. Bove and Dr. Weinstock-Guttman will review: The effects that aging may have on patients with MS The interplay between menopause and MS How aging may affect the approach to disease management EMD Serono is a business of Merck KGaA, Darmstadt, Germany. ©EMD Serono, Inc. All rights reserved. US/NPR/1019/0520B

Host: Jennifer Caudle, DO Guest: Riley Bove, MD Guest: Bianca Weinstock-Guttman, MD The disease course of multiple sclerosis (MS) can take many paths based on numerous factors, including age at diagnosis, gender, and MS subtype. Layered upon the typical MS management challenges are those that can occur with the physical and physiological changes of the normal aging process. How might the care of a patient with MS need to be modified as they age? In this discussion, Dr. Bove and Dr. Weinstock-Guttman will review: The effects that aging may have on patients with MS The interplay between menopause and MS How aging may affect the approach to disease management EMD Serono is a business of Merck KGaA, Darmstadt, Germany. ©EMD Serono, Inc. All rights reserved. US/NPR/1019/0520B

Host: Jennifer Caudle, DO Guest: Riley Bove, MD Guest: Bianca Weinstock-Guttman, MD The disease course of multiple sclerosis (MS) can take many paths based on numerous factors, including age at diagnosis, gender, and MS subtype. Layered upon the typical MS management challenges are those that can occur with the physical and physiological changes of the normal aging process. How might the care of a patient with MS need to be modified as they age? In this discussion, Dr. Bove and Dr. Weinstock-Guttman will review: The effects that aging may have on patients with MS The interplay between menopause and MS How aging may affect the approach to disease management EMD Serono is a business of Merck KGaA, Darmstadt, Germany. ©EMD Serono, Inc. All rights reserved. US/NPR/1019/0520B

Host: Jennifer Caudle, DO Guest: Catherine Apicella, MPT, PYT-C, PRPC With less and less primary care physicians partnering with physical therapists, it’s time we ask: are we doing ourselves—and our patients—a disservice by not taking advantage of this option? To find out, Dr. Jennifer Caudle sits down with physical therapist Catherine Apicella to discuss the often-overlooked benefits of physical therapy and how primary care physicians and physical therapists can work together to benefit their patients.

Host: Jennifer Caudle, DO Guest: Catherine Apicella, MPT, PYT-C, PRPC With less and less primary care physicians partnering with physical therapists, it’s time we ask: are we doing ourselves—and our patients—a disservice by not taking advantage of this option? To find out, Dr. Jennifer Caudle sits down with physical therapist Catherine Apicella to discuss the often-overlooked benefits of physical therapy and how primary care physicians and physical therapists can work together to benefit their patients.

Host: Jennifer Caudle, DO Guest: Catherine Apicella, MPT, PYT-C, PRPC With less and less primary care physicians partnering with physical therapists, it’s time we ask: are we doing ourselves—and our patients—a disservice by not taking advantage of this option? To find out, Dr. Jennifer Caudle sits down with physical therapist Catherine Apicella to discuss the often-overlooked benefits of physical therapy and how primary care physicians and physical therapists can work together to benefit their patients.

Host: Patricia K. Coyle, MD Guest: Clyde E. Markowitz, MD Please note: This activity is no longer available for continuing education credit. Multiple sclerosis (MS) is one of the leading causes of disability worldwide. As the treatment armamentarium continues to grow, patient involvement in the development of an effective treatment strategy is becoming increasingly important. In this Clinical ExchangesSM activity, leading MS specialists discuss issues of diagnosing MS, initiating treatment, and switching therapies, all in the context of practical shared decision-making techniques demonstrated by their own patients.

Host: Patricia K. Coyle, MD Guest: Clyde E. Markowitz, MD Please note: This activity is no longer available for continuing education credit. Multiple sclerosis (MS) is one of the leading causes of disability worldwide. As the treatment armamentarium continues to grow, patient involvement in the development of an effective treatment strategy is becoming increasingly important. In this Clinical ExchangesSM activity, leading MS specialists discuss issues of diagnosing MS, initiating treatment, and switching therapies, all in the context of practical shared decision-making techniques demonstrated by their own patients.

Host: Patricia K. Coyle, MD Guest: Clyde E. Markowitz, MD Please note: This activity is no longer available for continuing education credit. Multiple sclerosis (MS) is one of the leading causes of disability worldwide. As the treatment armamentarium continues to grow, patient involvement in the development of an effective treatment strategy is becoming increasingly important. In this Clinical ExchangesSM activity, leading MS specialists discuss issues of diagnosing MS, initiating treatment, and switching therapies, all in the context of practical shared decision-making techniques demonstrated by their own patients.

Host: Jennifer Caudle, DO Guest: Catherine Apicella, MPT, PYT-C, PRPC Guest: Crystal Gouldey Frustrating multiple sclerosis (MS) symptoms like urinary frequency and incontinence can be detrimental to a patient’s quality of life, but there are resources available to help. To explore the benefits of pelvic floor physical therapy for MS, Dr. Jennifer Caudle sits down with two special guests: physical therapist Catherine Apicella from CORE 3 Physical Therapy and her patient—and ReachMD’s very own employee—Crystal Gouldey.

Host: Jennifer Caudle, DO Guest: Catherine Apicella, MPT, PYT-C, PRPC Guest: Crystal Gouldey Frustrating multiple sclerosis (MS) symptoms like urinary frequency and incontinence can be detrimental to a patient’s quality of life, but there are resources available to help. To explore the benefits of pelvic floor physical therapy for MS, Dr. Jennifer Caudle sits down with two special guests: physical therapist Catherine Apicella from CORE 3 Physical Therapy and her patient—and ReachMD’s very own employee—Crystal Gouldey.

Host: Jennifer Caudle, DO Guest: Catherine Apicella, MPT, PYT-C, PRPC Guest: Crystal Gouldey Frustrating multiple sclerosis (MS) symptoms like urinary frequency and incontinence can be detrimental to a patient’s quality of life, but there are resources available to help. To explore the benefits of pelvic floor physical therapy for MS, Dr. Jennifer Caudle sits down with two special guests: physical therapist Catherine Apicella from CORE 3 Physical Therapy and her patient—and ReachMD’s very own employee—Crystal Gouldey.