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“My most powerful content is when I lead with my voice as a mom because I have the same concerns about keeping my kids safe as my audience does. It's a powerful and effective way to find common ground with people,” says Dr. Jess Steier, a popular public health scientist and science communicator seeking to bridge divides and foster trust through empathetic, evidence-based communication. Dr. Steier has several platforms from which to do this work, including Unbiased Science -- a communication hub that uses multiple social media platforms and other communications channels to share validated health and science information -- and as executive director of the Science Literacy Lab, a nonprofit organization dedicated to reaching a diverse audience seeking clarity and reliable information on scientific topics. “The science is less than half the battle,” she explains. “It's about how to communicate with empathy.”Join Raise the Line host Lindsey Smith for a valuable conversation that explores:What sources Dr. Steier relies on to validate informationHow she uses “escape room” exercises to train clinicians on empathetic communicationWhy tailored, story-driven messages reach audiences more effectively than facts.Mentioned in this episode:Unbiased Science If you like this podcast, please share it on your social channels. You can also subscribe to the series and check out all of our episodes at www.osmosis.org/podcast
This week on Faisel and Friends, we are discussing Reclaiming the Human Interaction in The Age of AI. Faisel and Dan are talking with Dr. Steven Waldren & Dr. Jay Lee.Our conversation explores empowering clinicians with technology, optimizing team collaboration with AI, and reclaiming the narrative around primary care physicians as trusted voices of wellness.This episode was recorded live at FMX, the AAFP's premier Family Medicine conference! Learn more about FMX here: https://www.aafp.org/events/fmx/2026.html
This week, we look at new research on potassium optimization in patients with defibrillators, reducing antihypertensive therapy in nursing homes, an mRNA influenza vaccine, and belzutifan for rare neuroendocrine tumors. We review long QT syndrome and present a case of abnormal behavior and seizures in a young man. We also explore perspectives on primary care reform, tobacco cessation in HIV and tuberculosis care, corporate control in health care, and the simple power of compassion with ice cream.
Doctors Lisa and Sara talk to Consultant Nephrologist Dr Darren Green about patients with Type 2 Diabetes who also have Chronic Kidney Disease and Heart Failure. We go through a hypothetical case to illustrate some of the finer points of management that can commonly get missed or might not be appreciated. A really detailed talk full of useful practice enhancing tips for this complex group of patients. Disclaimer: This episode was supported by Greater Manchester NHS who received support from Boehringer. You can use these podcasts as part of your CPD - we don't do certificates but they still count :) Resources: Dr Kevin Fernando counselling diabetic patients starting an SGLT2 Inhibitors like Dapagliflozin or Empagliflozin: https://www.youtube.com/watch?v=pc99SdtlsyU Diabetes UK counselling sheets on SGLT2 inhibitors: https://www.diabetes.org.uk/about-diabetes/looking-after-diabetes/treatments/tablets-and-medication/sglt2-inhibitors Kidney Care UK Patient Booklets: https://kidneycareuk.org/get-support/free-resources/patient-information-booklets/ Pumping Marvellous Heart Failure Charity with patient resources: https://pumpingmarvellous.org/ International Society for Nephrology Toolkit for Initiating or Changing RAASi - Renin Angiotensin Aldosterone System Inhibitors (like ACEis such as Lisinopril or Ramipril, or ARBs like Candesartan on Losartan): https://www.theisn.org/initiatives/toolkits/raasi-toolkit/ Royal College of General Practitioners Acute Renal Failure Toolkit: https://elearning.rcgp.org.uk/course/info.php?id=899 CONFIDENCE trial: Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes | New England Journal of Medicine: https://www.nejm.org/doi/full/10.1056/NEJMoa2410659 ATLAS trial: Efficacy and safety of high-dose lisinopril in chronic heart failure patients at high cardiovascular risk, including those with diabetes mellitus: https://pubmed.ncbi.nlm.nih.gov/11071803/ Metformin lactic acidosis Metformin in Patients With Type 2 Diabetes and Kidney Disease: A Systematic Review: https://jamanetwork.com/journals/jama/article-abstract/2084896 UK AKI Summit report UKKA AKI Summit Report + Recommendations: https://share.google/7uw1GPQ5sV2riJtiV RCGP AKI follow up post discharge recommendations: https://bjgpopen.org/content/early/2020/06/15/bjgpopen20X101054/tab-figures-data?versioned=true ___ We really want to make these episodes relevant and helpful: if you have any questions or want any particular areas covered then contact us on Twitter @PCKBpodcast, or leave a comment on our quick anonymous survey here: https://pckb.org/feedback Email us at: primarycarepodcasts@gmail.com ___ This podcast has been made with the support of GP Excellence and Greater Manchester Integrated Care Board. Given that it is recorded with Greater Manchester clinicians, the information discussed may not be applicable elsewhere and it is important to consult local guidelines before making any treatment decisions. The information presented is the personal opinion of the healthcare professional interviewed and might not be representative to all clinicians. It is based on their interpretation of current best practice and guidelines when the episode was recorded. Guidelines can change; To the best of our knowledge the information in this episode is up to date as of it's release but it is the listeners responsibility to review the information and make sure it is still up to date when they listen. Dr Lisa Adams, Dr Sara MacDermott and their interviewees are not liable for any advice, investigations, course of treatment, diagnosis or any other information, services or products listeners might pursue as a result of listening to this podcast - it is the clinicians responsibility to appraise the information given and review local and national guidelines before making treatment decisions. Reliance on information provided in this podcast is solely at the listeners risk. The podcast is designed to be used by trained healthcare professionals for education only. We do not recommend these for patients or the general public and they are not to be used as a method of diagnosis, opinion, treatment or medical advice for the general public. Do not delay seeking medical advice based on the information contained in this podcast. If you have questions regarding your health or feel you may have a medical condition then promptly seek the opinion of a trained healthcare professional.
Maine Family Planning clinics treat STDs, bronchitis and tick bites. Because they also provide abortions, they've been hit by a new federal law that cuts them out of Medicaid. Now, they're cutting back on services to try to survive.For sponsor-free episodes of Consider This, sign up for Consider This+ via Apple Podcasts or at plus.npr.org. Email us at considerthis@npr.org.This episode was produced by Connor Donevan and Ava Berger, with audio engineering by Jimmy Keeley. It was edited by Diane Webber and Courtney Dorning. Our executive producer is Sami Yenigun.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy
If you've ever been told to "just eat less and move more," or struggled with weight despite doing everything "right," this episode will validate your experience and challenge the harmful myths that still exist—even in medicine. In this deeply personal episode, I will share what happened when a colleague dismissed obesity as "lifestyle driven" rather than a chronic disease. Her response is a powerful reminder that this condition is far more complex than willpower. I will also open up about my own decades-long journey—including training for two full Ironmans and seven marathons—and why even with extreme dedication, I never reached a "normal" BMI. My story, combined with my clinical expertise, will reveal the biological, genetic, environmental, and social factors that make obesity a chronic disease affecting millions. Episode Highlights: Why 40-70% of obesity cases are driven by genetics, not lifestyle choices The real struggles patients face: severe calorie restriction, exercising 6-7 days a week, and still not losing weight Medical conditions and medications that cause weight gain—from PCOS to antidepressants How food deserts, safety concerns, and financial barriers create obstacles beyond personal control Four practical ways to show compassion to someone living with obesity Connect with Dr. Alicia Shelly: Website | drshellymd.com Facebook | www.facebook.com/drshellymd Instagram | @drshellymd Linked In | www.linkedin.com/in/drshellymd Twitter | @drshellymd About Dr. Alicia Shelly Dr. Alicia Shelly was raised in Atlanta, GA. She received her Doctorate of Medicine from Case Western Reserve University School of Medicine in Cleveland, OH. Dr. Shelly has been practicing Primary Care and Obesity medicine since 2014. In 2017, she became a Diplomat of the American Board of Obesity Medicine. She is the lead physician at the Wellstar Medical Center Douglasville. She started a weekly podcast & Youtube channel entitled Back on Track: Achieving Healthy Weight loss, where she discusses how to get on track and stay on track with your weight loss journey. She has spoken for numerous local and national organizations, including the Obesity Medicine Association, and the Georgia Chapter of the American Society of Metabolic and Bariatric Surgeons. She has been featured on CNN, Fox 5 News, Bruce St. James Radio show, Upscale magazine, and Shape.com. She was named an honoree of the 2021 Atlanta Business Chronicle's 40 under 40 award. She also is a collaborating author for the, "Made for More: Physician Entrepreneurs who Live Life and Practice Medicine on their own terms''. Resources: FREE! Discover the 5 Reasons Your Weight-Loss Journey Has Gotten Derailed (And How To Get Back On Track!)
In this episode, we tackle the challenge of separating allergy fact from fiction in an age of rampant online misinformation. Dr. Zachary Rubin, a double board-certified pediatrician and allergist, shares insights on common allergy myths circulating on social media. We explore misconceptions about food allergies vs. intolerances, respiratory allergies, eczema management, anaphylaxis treatment, and allergy testing interpretation. Learn how to navigate patient conversations about gluten sensitivity, pet allergies, and "natural" allergy cures. This episode provides primary care clinicians with practical strategies to address patient concerns rooted in online misinformation and optimize allergy diagnosis and management in clinical practice.
(REWIND) Season 1, Episode 14: Dr. Chiti Parikh is an author and integrative medicine physician at New York Presbyterian – Weill Cornell Medical Center. Listen to Chiti talk about the definition of integrative medicine, the types of patients who seek out integrative care and the importance of addressing spirituality during patient visits.Check out Dr. Parikh's book Intentional Health here.
“I realized that rather than talking one-to-one with patients in the exam room, you could talk one-to-many on social media,” says Dr. Kevin Pho, explaining the origins of KevinMD, the highly influential information sharing site he created for physicians, medical students and patients twenty years ago. Since then, KevinMD has become a valuable space for clinicians and patients to share stories and perspectives on topics from burnout and moral injury to technology and trust. In this conversation with Raise the Line host Michael Carrese, Dr. Pho reflects on the dual paths that have defined his career: as a practicing internal medicine physician and as one of healthcare's most trusted online voices. And despite the challenges of doing so, Dr. Pho encourages other medical providers to follow his lead. “Patients are going online, and if physicians are not there, they're going to get information that's perhaps politically-driven or simply inaccurate.”This thoughtful conversation also explores: How social media has reshaped health communicationThe risks and rewards for clinicians of having an online presence Why medical schools should teach negotiating skillsMentioned in this episode:KevinMDEstablishing, Managing and Protecting Your Online Reputation If you like this podcast, please share it on your social channels. You can also subscribe to the series and check out all of our episodes at www.osmosis.org/podcast
PeerView Family Medicine & General Practice CME/CNE/CPE Video Podcast
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/APA/IPCE information, and to apply for credit, please visit us at PeerView.com/SMZ865. CME/MOC/NCPD/CPE/AAPA/APA/IPCE credit will be available until November 5, 2026.Brain Health Morning Report: Adapting Primary Care Practice and Workflows to Meet the Needs of an Aging Population In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/APA/IPCE information, and to apply for credit, please visit us at PeerView.com/SMZ865. CME/MOC/NCPD/CPE/AAPA/APA/IPCE credit will be available until November 5, 2026.Brain Health Morning Report: Adapting Primary Care Practice and Workflows to Meet the Needs of an Aging Population In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.
PeerView Neuroscience & Psychiatry CME/CNE/CPE Audio Podcast
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/APA/IPCE information, and to apply for credit, please visit us at PeerView.com/SMZ865. CME/MOC/NCPD/CPE/AAPA/APA/IPCE credit will be available until November 5, 2026.Brain Health Morning Report: Adapting Primary Care Practice and Workflows to Meet the Needs of an Aging Population In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.
PeerView Neuroscience & Psychiatry CME/CNE/CPE Video Podcast
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/APA/IPCE information, and to apply for credit, please visit us at PeerView.com/SMZ865. CME/MOC/NCPD/CPE/AAPA/APA/IPCE credit will be available until November 5, 2026.Brain Health Morning Report: Adapting Primary Care Practice and Workflows to Meet the Needs of an Aging Population In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/APA/IPCE information, and to apply for credit, please visit us at PeerView.com/SMZ865. CME/MOC/NCPD/CPE/AAPA/APA/IPCE credit will be available until November 5, 2026.Brain Health Morning Report: Adapting Primary Care Practice and Workflows to Meet the Needs of an Aging Population In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/APA/IPCE information, and to apply for credit, please visit us at PeerView.com/SMZ865. CME/MOC/NCPD/CPE/AAPA/APA/IPCE credit will be available until November 5, 2026.Brain Health Morning Report: Adapting Primary Care Practice and Workflows to Meet the Needs of an Aging Population In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.
PeerView Family Medicine & General Practice CME/CNE/CPE Audio Podcast
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/APA/IPCE information, and to apply for credit, please visit us at PeerView.com/SMZ865. CME/MOC/NCPD/CPE/AAPA/APA/IPCE credit will be available until November 5, 2026.Brain Health Morning Report: Adapting Primary Care Practice and Workflows to Meet the Needs of an Aging Population In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/APA/IPCE information, and to apply for credit, please visit us at PeerView.com/SMZ865. CME/MOC/NCPD/CPE/AAPA/APA/IPCE credit will be available until November 5, 2026.Brain Health Morning Report: Adapting Primary Care Practice and Workflows to Meet the Needs of an Aging Population In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.
https://gptriage.com/ In this episode of The Medics Money Podcast, Dr. Tommy Perkins discuss the emerging role of artificial intelligence in primary care. The conversation explores the benefits of GP Triage, an autonomous triage and booking solution designed to improve patient access and streamline operations in GP practices. Key topics covered include the system's customization options, funding strategies, language accessibility, digital inclusion, and the future of AI in healthcare. The guests provide insights into how GP Triage was developed, its impact on practice efficiency, and its potential to enhance patient care and satisfaction. The episode concludes with predictions on the future transformation of primary care by AI technologies. 00:00 Introduction to Medics Money Podcast 00:51 Challenges in Primary Care 01:57 Meet the Guests 03:04 What is GP Triage? 04:57 How GP Triage Works 06:37 Customization and Benefits of GP Triage 08:41 Funding and ROI for GP Triage 15:34 Addressing Digital Exclusion 19:02 Future of AI in Healthcare 25:44 Getting Started with GP Triage
In this episode, we look at new trials on deferring arterial catheterization in shock, beta-blocker use after myocardial infarction, and a treatment for triple-negative breast cancer. We review acromegaly. A case describes a man with dyspnea, edema, and pacemaker lead displacement. We explore perspectives on the burdens of primary care, the erosion of harm reduction, child health policy, and the meaning of hospice.
Joshua Barocas is an associate professor of medicine at the University of Colorado Anschutz Medical Campus. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. J.A. Barocas. The Erosion of Harm Reduction. N Engl J Med 2025;393:1865-1867. B.A. Barsky, A. Caplan-Bricker, and C. Robertson. Religious Liberty as a Shield for Public Health — The Case of Overdose-Prevention Centers. N Engl J Med 2025;393:1867-1869.
“We've created this ecosystem where the vast majority of information on social media, particularly in nutrition science, is inaccurate or misleading,” says Dr. Jessica Knurick, a registered dietitian and Ph.D. in nutrition science specializing in chronic disease prevention. As you'll learn on this episode of Raise the Line with host Lindsey Smith, countering that trend has become Dr. Knurick's focus in the past several years, and her talent for translating complex scientific information into practical guidance has attracted a large following on social media. Beyond equipping her audience with the tools to think critically and make informed choices for themselves, she also wants them to make the connection between the generally poor health status of most Americans with public policies on food and health and advocate for more beneficial approaches. “We can create systems that put the most people in the position to succeed versus putting the most people in the position to fail.” Tune in to learn from this trusted voice on nutrition, food policy, and public health as she shares her perspectives on: Strategies for risk reduction and behavior changeWhat can rebuild trust in medical information How you can cut through the noise and spot misinformation onlineMentioned in this episode:Dr. Knurick's WebsiteTikTok ChannelInstagram FeedFacebook Page If you like this podcast, please share it on your social channels. You can also subscribe to the series and check out all of our episodes at www.osmosis.org/podcast
Is aging itself a treatable condition? How can we mindfully approach the longevity, aesthetics, and wellness industries? In this episode, we connect with Dr. Sofia Din to see what it means to live longer, healthier, and more beautifully using proven integrative treatments… Dr. Din is a board-certified anti-aging expert, integrative medicine physician, and MD specializing in Primary Care, Geriatrics, and Aesthetic Anti-Aging Practices. Based in New York with more than 15 years of experience, her work focuses on helping men and women extend their vitality, productivity, and confidence. Join the conversation to learn about: The science behind "aging syndrome" and how to prevent or reverse its symptoms. Non-pharmaceutical treatments and lifestyle strategies to promote longevity and radiance. The link between metabolic health, beauty, and emotional well-being. Dr. Din offers a wide range of solutions, including skincare therapies, customized weight loss programs, IV-vitamin infusions, hormone optimization, and medical treatments such as medical marijuana and addiction therapy. Her book, Do We Really Need Botox? – A Handbook of Anti-Aging, explores her progressive theory that aging is a disease syndrome with both physical and psychological dimensions, some of which often manifest in conditions like heart disease, dementia, cancer, and osteoporosis. In addition to her medical practice, Dr. Din founded the Juvanni Foundation for Single Mothers, a nonprofit dedicated to improving the lives of single mothers and their children through economic, physical, and emotional support. So stay up-to-date with Dr. Din and her work, visit www.sofiadinmd.com!
In this powerful episode, I will break down one of the biggest developments in obesity and diabetes treatment in U.S. history. Two major pharmaceutical companies - Eli Lilly and Novo Nordisk - have reached a groundbreaking agreement with the administration that will drastically reduce the prices of popular medications like Wegovy, Ozempic, and Zepbound. This pricing model could transform how obesity medications are covered, distributed, and accessed across Medicare, Medicaid, and direct-to-consumer platforms. Tune in to learn what this new deal means for patients, healthcare providers, and public health overall—and why it's being called a game changer for people struggling with obesity and related health conditions. Episode Highlights: Major price cuts announced for Wegovy, Ozempic, and Zepbound under a new federal deal Medicare to cover obesity drugs for the first time through a five-year pilot program Medicaid given the option to join discounted pricing starting 2026 Team Rx launches a direct-to-consumer model cutting out costly middlemen Lower cash prices for GLP-1 medications and upcoming oral versions Eli Lilly and Novo Nordisk to invest billions in U.S. manufacturing Program expected to improve access, affordability, and supply of obesity and diabetes meds Ongoing push for the Treat and Reduce Obesity Act to expand national coverage Connect with Dr. Alicia Shelly: Website | drshellymd.com Facebook | www.facebook.com/drshellymd Instagram | @drshellymd Linked In | www.linkedin.com/in/drshellymd Twitter | @drshellymd About Dr. Alicia Shelly Dr. Alicia Shelly was raised in Atlanta, GA. She received her Doctorate of Medicine from Case Western Reserve University School of Medicine in Cleveland, OH. Dr. Shelly has been practicing Primary Care and Obesity medicine since 2014. In 2017, she became a Diplomat of the American Board of Obesity Medicine. She is the lead physician at the Wellstar Medical Center Douglasville. She started a weekly podcast & Youtube channel entitled Back on Track: Achieving Healthy Weight loss, where she discusses how to get on track and stay on track with your weight loss journey. She has spoken for numerous local and national organizations, including the Obesity Medicine Association, and the Georgia Chapter of the American Society of Metabolic and Bariatric Surgeons. She has been featured on CNN, Fox 5 News, Bruce St. James Radio show, Upscale magazine, and Shape.com. She was named an honoree of the 2021 Atlanta Business Chronicle's 40 under 40 award. She also is a collaborating author for the, "Made for More: Physician Entrepreneurs who Live Life and Practice Medicine on their own terms''. Resources: FREE! Discover the 5 Reasons Your Weight-Loss Journey Has Gotten Derailed (And How To Get Back On Track!)
Reporter, Aisling Kenny discusses new HSE figures which show that in August this year there were children in Dublin waiting 13 years to be seen by a primary care psychologist.
Discover why establishing a relationship with a primary care doctor is one of the most important investments in your long-term health. From preventative screenings to managing chronic conditions, we break down what a PCP really does for you.For more, visit https://amanacareclinic.com/ Amana Care Clinic City: Davenport Address: 2162 W Kimberly Rd, Website: https://amanacareclinic.com/
Could studying the DNA of extinct animals – or even bringing them back to life – help us save today's endangered species and inform modern medicine? That may sound like the premise for a Hollywood movie, but it's work that our Raise the Line guest, Dr. Beth Shapiro, is actually engaged in as Chief Science Officer at Colossal Biosciences, which describes itself as the world's first and only de-extinction company. “It's not just about learning about the past. It's learning about the past so we have more validated scientific information that we can use to predict what we can do to better influence the future,” she tells host Michael Carrese. An internationally-renowned evolutionary molecular biologist and paleogeneticist, Dr. Shapiro is a pioneer in ancient DNA research and has successfully sequenced genomes, like that of the dodo, to study evolution and the impact on humans. At Colossal Biosciences, she leads teams working to bring back traits of extinct species such as the mammoth, not for spectacle, but to restore ecological balance. “When species become extinct, you lose really fundamental interactions between species that existed in that ecosystem. By taking a species that's alive today and editing its DNA so that it resembles those extinct species, we can functionally replace those missing ecological interactions.” Tune into this utterly fascinating conversation to hear about what Jurassic Park got wrong, the positive ecological impact of reintroducing giant tortoises to Mauritius, and the ethics of using gene editing and other biotechnologies. Mentioned in this episode:Colossal Biosciences If you like this podcast, please share it on your social channels. You can also subscribe to the series and check out all of our episodes at www.osmosis.org/podcast
We're discussing Empowering Patients to Make the Best Decisions! Faisel and Dan are joined by Dr. Alex McDonald: Family and Sports Medicine Physician, AAFP Vaccine Science Fellow, and Immediate Past President of the California Academy of Family Physicians.Our conversation revolves around exploring vaccination options with patients, building a movement from an online immunization community, and prescribing lifestyle medicine.
Even though PC is the only component of healthcare shown to increase life expectancy and is crucial to achieving healthcare equity, outcomes, quality and value PC remains on life support. For example, an August National Academy of Medicine report concluded, “despite PC's essential value for the health of the nation, more than 100 million people across rural and urban communities in the US are experiencing a calamitous lack of access to primary care.” Among numerous problems: PC accounts for less than 5% of total healthcare spending; there are too few primary care clinicians and too many, at 7,501, HRSA PC shortage areas; PC clinicians are inadequately reimbursed and maldistributed. Consequently, PC struggles to adequately address prevention, the social determinants of health, integrate care particularly behavioral health services and ultimately achieve optimal value. In “Wonderful and Broken,” Prof. Brennan discusses how PC care can be improved and organizations that are at least on the path toward stable and effective PC delivery. (Listeners may recall I interviewed Prof. Brennan in October 2024 regarding his just published previous work, “The Transformation of American Health Insurance” & that this is at least my 5th PC discussion dating back to 2013.)Information on Prof Brennan's book is found at: https://www.press.jhu.edu/books/title/54051/wonderful-and-broken?srsltid=AfmBOor4SJMCBvCYWck_6Aobdxk-ZUJgusnceOxxT-eghoU8CkPc3kMl. This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.thehealthcarepolicypodcast.com
A new report says health systems want to expand their primary care footprint. David W. Johnson and Julie Murchinson discuss health systems' motivations and whether patients will benefit from those expansion plans on, “More Primary Care, Please,” the new episode of the 4sight Health Roundup podcast, moderated by David Burda.
In this episode, we discuss long-term outcomes after chest-wall irradiation for breast cancer, new treatments for psoriasis and obesity, and early results on a vaccine for Lassa fever. We review opioid deprescribing and a clinical case describes spiraling into a distant past. Perspectives examine the corporatization of health care, the health effects of new energy legislation, and Medicaid cuts affecting U.S. children.
Yashaswini Singh is an assistant professor of health services, policy, and practice at Brown University. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. Y. Singh. The Antitrust Antidote to Hospital and Nursing Home Corporatization — Promises and Pitfalls. N Engl J Med 2025;393:1761-1764.
Doctors Sara and Lisa speak to Dr Chris Nortcliff who is a GP and Chief Clinical Information Officer for Greater Manchester Primary Care Provider Board. The discussion is focussed around all things digital in primary care. We start with an overview of how the digital environment is set up within Greater Manchester. We then spend some time talking about digital inclusion - covering how to find people, how to help upskill them to be more digitally literate, and how to support better access to digital services. We also explore what is available in the digital space to help in primary care, and touch on AI and large language models. You can use these podcasts as part of your CPD - we don't do certificates but they still count :) Resources: Greater Manchester Care Record: https://gmwearebettertogether.com/ Health Innovation Manchester: https://healthinnovationmanchester.com/ Greater Manchester Digital First Primary Care: https://healthinnovationmanchester.com/our-work/gm-digital-first-primary-care/ Digital Skills Map: https://greatermanchester-ca.gov.uk/what-we-do/digital/get-online-greater-manchester/greater-manchester-wide-support/get-online-greater-manchester-digital-skills-map/ National Databank: https://www.goodthingsfoundation.org/our-services/national-databank The Good Things Foundation: https://www.goodthingsfoundation.org/ NHS App: https://www.nhs.uk/nhs-app/ Digital Facilitator Team: https://gmpcb.org.uk/general-practice/digital-transformation/dfpc-programme-explained/meet-the-team/ Greater Manchester Primary Care Provider Board Website: https://gmpcb.org.uk/general-practice/digital-transformation/ Clinical safety standards - DCB 0129: https://digital.nhs.uk/data-and-information/information-standards/governance/latest-activity/standards-and-collections/dcb0129-clinical-risk-management-its-application-in-the-manufacture-of-health-it-systems/ Clinical safety standards - DCB0160: https://digital.nhs.uk/data-and-information/information-standards/governance/latest-activity/standards-and-collections/dcb0160-clinical-risk-management-its-application-in-the-deployment-and-use-of-health-it-systems/ Digital Inclusion Framework by NHS England: https://www.england.nhs.uk/long-read/inclusive-digital-healthcare-a-framework-for-nhs-action-on-digital-inclusion/ Digital Inclusion Heat Map: https://www.thrivebydesign.org.uk/digital-exclusion-heatmap ___ We really want to make these episodes relevant and helpful: if you have any questions or want any particular areas covered then contact us on Twitter @PCKBpodcast, or leave a comment on our quick anonymous survey here: https://pckb.org/feedback Email us at: primarycarepodcasts@gmail.com ___ This podcast has been made with the support of GP Excellence and Greater Manchester Integrated Care Board. Given that it is recorded with Greater Manchester clinicians, the information discussed may not be applicable elsewhere and it is important to consult local guidelines before making any treatment decisions. The information presented is the personal opinion of the healthcare professional interviewed and might not be representative to all clinicians. It is based on their interpretation of current best practice and guidelines when the episode was recorded. Guidelines can change; To the best of our knowledge the information in this episode is up to date as of it's release but it is the listeners responsibility to review the information and make sure it is still up to date when they listen. Dr Lisa Adams, Dr Sara MacDermott and their interviewees are not liable for any advice, investigations, course of treatment, diagnosis or any other information, services or products listeners might pursue as a result of listening to this podcast - it is the clinicians responsibility to appraise the information given and review local and national guidelines before making treatment decisions. Reliance on information provided in this podcast is solely at the listeners risk. The podcast is designed to be used by trained healthcare professionals for education only. We do not recommend these for patients or the general public and they are not to be used as a method of diagnosis, opinion, treatment or medical advice for the general public. Do not delay seeking medical advice based on the information contained in this podcast. If you have questions regarding your health or feel you may have a medical condition then promptly seek the opinion of a trained healthcare professional.
According to the Bloomberg School of Public Health at Johns Hopkins University, women make up 70% of the global healthcare workforce but hold only about 25% of leadership positions. Our guest today on Raise the Line, Dr. Roopa Dhatt, has been a leading voice in the movement to correct that imbalance through co-founding an organization called Women in Global Health (WGH), which has established chapters in over 60 countries since it started a decade ago. Dr. Dhatt is also pursuing that agenda and addressing other pressing issues in healthcare as a Young Global Leader at the World Economic Forum. “We're changing the equation so women delivering health are also viewed and valued as leaders,” says the internal medicine physician and assistant professor at Georgetown University School of Medicine. Beyond leadership equity, Dr. Dhatt is also seeking to address systemic pay inequities and high levels of violence and harassment experienced by women in the health sector, issues that were highlighted in research conducted by WGH. Although WGH has seen high-level success influencing policy at the World Health Organization and United Nations, Dr. Dhatt says the heart of its success is local. “Women community health workers have begun to see themselves as leaders and the heroines of health in their communities. That's profound change.” Join host Michael Carrese for a probing conversation that identifies the structural barriers blocking advancement for women and that explains why the health of communities and the planet depend on inclusive leadership.Mentioned in this episode:Women in Global HealthWHO Report: Delivered By Women, Led By MenDr. Roopa Dhatt on LinkedIn If you like this podcast, please share it on your social channels. You can also subscribe to the series and check out all of our episodes at www.osmosis.org/podcast
The challenges facing American healthcare are substantial, but Dr. Troy Brennan, who teaches at the Harvard T.H. Chan School of Public Health, says they all stem from long-simmering issues in primary care.See omnystudio.com/listener for privacy information.
Today we are talking to a primary care doc who has become a multimillionaire and is now essentially financially independent. Their financial success has allowed her career military spouse to retire. She said she loves her career and despite their financial situation she has no desire to quit working. They live in a high cost of living area and are a great example that if you do the right, boring, consistent thing over time - you will reach your financial goals. After the interview we are talking about financial independence for Finance 101. Goodman Capital is a premier real estate credit investment firm specializing in senior-secured, low loan-to-value lending on Class A properties in prime markets across the greater New York metro area. Founded on a family legacy dating back to 1987, Goodman has closed more than $850 million+ across 95+ loans with a track record of zero principal loss. Their flagship private mortgage REIT, Liquid Credit Strategy Fund I, delivered a steady 9% net dividend yield since inception at a very conservative sub-50% LTV. Invest in tax-efficient, high-yield, risk-adjusted debt investment strategies with Goodman Capital at https://www.whitecoatinvestor.com/goodman The White Coat Investor has been helping doctors, dentists, and other high-income professionals with their money since 2011. Our free personal finance resource covers an array of topics including how to use your retirement accounts, getting a doctor mortgage loan, how to manage your student loans, buying physician disability and malpractice insurance, asset allocation & asset location, how to invest in real estate, and so much more. We will help you learn how to manage your finances like a pro so you can stop worrying about money and start living your best life. If you're a high-income professional and ready to get a "fair shake" on Wall Street, The White Coat Investor is for you! Have you achieved a Milestone? You can be on the Milestones to Millionaire Podcast too! Apply here: https://whitecoatinvestor.com/milestones Find 1000's of written articles on the blog: https://www.whitecoatinvestor.com Our YouTube channel if you prefer watching videos to learn: https://www.whitecoatinvestor.com/youtube Student Loan Advice for all your student loan needs: https://studentloanadvice.com Join the community on Facebook: https://www.facebook.com/thewhitecoatinvestor Join the community on Twitter: https://twitter.com/WCInvestor Join the community on Instagram: https://www.instagram.com/thewhitecoatinvestor Join the community on Reddit: https://www.reddit.com/r/whitecoatinvestor Learn faster with our Online Courses: https://whitecoatinvestor.teachable.com Sign up for our Newsletter here: https://www.whitecoatinvestor.com/free-monthly-newsletter 00:00 MtoM Podcast #247 02:18 Primary Care Doc Becomes Multimillionaire and Retires Her Husband 11:56 Advice For Others 18:17 Financial Independence
“They say it takes a village to raise a child. I really think it takes a village to treat a patient,” says Dr. Lanae Mullane, a naturopathic doctor and clinical strategist who has spent years at the forefront of bridging functional medicine, nutraceutical development, and digital health. In this episode of Raise the Line, host Lindsey Smith explores Dr. Mullane's view that naturopathic medicine complements conventional care by expanding -- not replacing -- the clinical toolkit, and that collaboration should be the future of medicine. “At the end of the day, collaboration and connection create the best outcomes for the people we serve,” she says. Their in-depth conversation also spans the shifting landscape of women's hormone health, including the perimenopausal transition and long-overdue calls for research equity. “We're not just smaller versions of men. We need to have dedicated research for us.” Tune in to learn about the importance of grounding health in sustainable habits, rethinking midlife care for women, and how to help patients take ownership of their health.Mentioned in this episode:Joi + BlokesSuppCoDr. Mullane's Clinical Website If you like this podcast, please share it on your social channels. You can also subscribe to the series and check out all of our episodes at www.osmosis.org/podcast
This week, we look at new findings from the European prostate cancer screening study, advances in lung cancer therapy, physical therapy for meniscal tear, and a promising vaccine for Salmonella Paratyphi A. We review noninvasive liver fibrosis assessment and a complex clinical case, and explore perspectives on concierge care, kidney disease equity, WIC enrollment, community health, FDA regulation, and standing with colleagues in Gaza.
How do we fill the gaps in Arizona's primary care? Dr. Joshua Kaer, President of Midwestern University joined Arizona's Morning News to discuss what they are doing to help fill the gaps and explains what the residency program is.
In this episode of Quality Talks with Peggy O'Kane, Peggy welcomes Dr. Troyen Brennan, adjunct professor at the Harvard School of Public Health, former Chief Medical Officer at CVS Health and Aetna, and author of Wonderful and Broken.With decades of experience spanning academic medicine, hospital administration and retail health care, Troy brings candor and clarity to the challenges facing American health care and the promise of primary care reform.Troy's insights are both sobering and hopeful, pointing to a future where coordinated, data-driven primary care can finally fulfill its promise.Highlights:·Diagnosing a System Under Pressure: The limits of fee-for-service payment and why employer-sponsored insurance is reaching a breaking point.Building the Foundation for Better Care: The critical role of primary care in medicine's value-based future.Spotlighting Innovation Across the Map: Real-world examples of successful primary care transformation, including Catalyst Health in Texas and Southcentral Foundation in Alaska.Reimagining Accreditation for Modern Needs: Reflections on NCQA's Patient-Centered Medical Home and future redesigns.Clearing the Policy Bottleneck: Observations on policy inertia and how policymakers can accelerate change.This episode is a timely and thought-provoking update for healthcare executives, policymakers and clinicians committed to building a more sustainable, efficient health care system.Key Quote:The only way you can see a health care system that works in the future is if it's value based—that it's prospective payment and risk on the providers for the elaboration of care provided.If we believe what most people write about these things, we've got 25 to 30% waste as a result of the fee-for-service system.If we move to a value-based approach, that's money that's going to fund the system, that extra third that we can put back into real health care. So you need a value-based approach.-- Troy Brennan, MDTime Stamps:(3:12) Employment-Based Health Care is Unsustainable (7:29) The Value-Based Future and Primary Care(10:00) Payment Disparities and Policy Inertia(22:00) Technology and Data Analytics in Advanced Primary Care(28:18) Peggy's ReflectionLinks:Connect with Troyen Brennan Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
This episode features Thomas A. Shaffrey, MD, Primary Care and Hospitalist at Steward Medical Group, sharing his insights on the No Surprises Act, the importance of strong contracting for practices, and the challenges facing U.S. hospitals and physicians. Dr. Shaffrey emphasizes the value of physician involvement in business and policy to ensure healthcare sustainability and patient access.
“It's kind of a miracle, frankly,” says Dr. John Buse, a distinguished professor at the University of North Carolina School of Medicine, referring to the effectiveness of GLP-1 receptor agonist medications such as Ozempic in treating type 2 diabetes, promoting significant weight loss, and reducing cardiovascular risk. As a physician scientist for the last three decades at UNC, Dr. Buse has played a key role in ushering in this new era of diabetes care, leading or participating in over 200 clinical studies on this class of drugs and others. “Nothing has impacted diabetes care like the GLP-1 receptor agonists. I have lots of patients whose diabetes was never well controlled who have seen all their metabolic problems essentially resolved.” In this fascinating conversation with Raise the Line host Lindsey Smith, Dr. Buse not only explains how these drugs work, but also provides a clear-eyed look at side effects, and addresses issues of cost and access. Join us for the remarkable story – including the role played by Gila monsters -- behind one of the biggest developments in medicine over the past several years from a world renowned diabetes researcher and clinician. Mentioned in this episode:UNC School of Medicine If you like this podcast, please share it on your social channels. You can also subscribe to the series and check out all of our episodes at www.osmosis.org/podcast
Riverside Healthcare Director of Population Health Liberty Erfe discusses the differences between the emergency room, immediate care, and primary care, and shares where to go when.
Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-456 Overview: Experiences of significant pain and anxiety during intrauterine device (IUD) insertion may lead patients to forgo this effective contraceptive option. Listen in as we discuss how to reduce procedural pain, address anxiety, and foster trust using updated guidelines and shared decision-making to improve patient satisfaction and support informed contraceptive choices. Episode resource links: Charles, D. N., Nagarsheth, M., & Oshman, L. (2025). Pain Management for IUD Insertion in Primary Care. American Family Physician, 111(4), 299-301. Dempsey, A., Aucoin, C., Stallings, W., Kulangara, A., & Sundstrom, B. (2025). Beyond pain medication: striving toward more patient-centered placement of intrauterine devices. Contraception, 110944. Estevez, E., Hem-Lee-Forsyth, S., Viechweg, N. D., John, S., & Menor, S. P. (2024). Advancing pain management protocols for intrauterine device insertion: integrating evidence-based strategies into clinical practice. Cureus, 16(6). Hoover, K., & Riley, K. (2025). Pain Management for In-Office Uterine and Cervical Procedures. Guest: Mariyan L. Montaque, DNP, FNP-BC Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com
Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-456 Overview: Experiences of significant pain and anxiety during intrauterine device (IUD) insertion may lead patients to forgo this effective contraceptive option. Listen in as we discuss how to reduce procedural pain, address anxiety, and foster trust using updated guidelines and shared decision-making to improve patient satisfaction and support informed contraceptive choices. Episode resource links: Charles, D. N., Nagarsheth, M., & Oshman, L. (2025). Pain Management for IUD Insertion in Primary Care. American Family Physician, 111(4), 299-301. Dempsey, A., Aucoin, C., Stallings, W., Kulangara, A., & Sundstrom, B. (2025). Beyond pain medication: striving toward more patient-centered placement of intrauterine devices. Contraception, 110944. Estevez, E., Hem-Lee-Forsyth, S., Viechweg, N. D., John, S., & Menor, S. P. (2024). Advancing pain management protocols for intrauterine device insertion: integrating evidence-based strategies into clinical practice. Cureus, 16(6). Hoover, K., & Riley, K. (2025). Pain Management for In-Office Uterine and Cervical Procedures. Guest: Mariyan L. Montaque, DNP, FNP-BC Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com
Seen TikTok videos about taking "just a little bit" of Ozempic or counting pen clicks instead of using the prescribed dose? That's microdosing, and it's showing up everywhere—from social media to patient discussions. In this episode, I will cut through the hype to explain what microdosing GLP-1 medications really means, why people are trying it (spoiler: cost and side effects), and what the research actually says. I will discuss the concept of "super responders" who seem to do well on lower doses, the lack of scientific backing for DIY microdosing, and the real risks of using compounded or diluted versions of these medications. Tune in to learn why working with your healthcare provider is essential for safe, effective dosing—and discover legitimate ways to manage side effects and costs without compromising your results. Episode Highlights: What microdosing GLP-1s actually means The difference between super responders and unsafe microdosing Why professional organizations don't endorse microdosing Hidden risks of compounded and diluted medications Safe alternatives for managing side effects and medication costs Connect with Dr. Alicia Shelly: Website | drshellymd.com Facebook | www.facebook.com/drshellymd Instagram | @drshellymd Linked In | www.linkedin.com/in/drshellymd Twitter | @drshellymd About Dr. Alicia Shelly Dr. Alicia Shelly was raised in Atlanta, GA. She received her Doctorate of Medicine from Case Western Reserve University School of Medicine in Cleveland, OH. Dr. Shelly has been practicing Primary Care and Obesity medicine since 2014. In 2017, she became a Diplomat of the American Board of Obesity Medicine. She is the lead physician at the Wellstar Medical Center Douglasville. She started a weekly podcast & Youtube channel entitled Back on Track: Achieving Healthy Weight loss, where she discusses how to get on track and stay on track with your weight loss journey. She has spoken for numerous local and national organizations, including the Obesity Medicine Association, and the Georgia Chapter of the American Society of Metabolic and Bariatric Surgeons. She has been featured on CNN, Fox 5 News, Bruce St. James Radio show, Upscale magazine, and Shape.com. She was named an honoree of the 2021 Atlanta Business Chronicle's 40 under 40 award. She also is a collaborating author for the, “Made for More: Physician Entrepreneurs who Live Life and Practice Medicine on their own terms''. Resources: FREE! Discover the 5 Reasons Your Weight-Loss Journey Has Gotten Derailed (And How To Get Back On Track!)
“It wasn't a profession, it was a way of life,” observes internationally respected psychiatrist Dr. Nasser Loza, reflecting on a century-long family legacy in mental health care that began when his grandfather founded The Behman Hospital in Cairo. In this candid Raise the Line conversation with host Michael Carrese, Dr. Loza traces the transformation of psychiatry he's witnessed in his long career as increases in classifications, payment bureaucracy, reliance on pharmaceuticals, and technological disruption have each left their mark. The cumulative costs associated with these changes have, he laments, pushed care out of reach for many and hindered the human connection that is key to the discipline. He describes his prescription for countering these trends as a focus on effective and modest aims. “Rather than saying, come and see me in therapy for five years and I will make a better person out of you, I think focusing on symptom-targeted help is going to be what is needed.” In this wide-ranging interview, you'll also learn about progress on advancing the rights of mental health patients and lowering stigmas, how to manage the rise of online therapy and use of AI chatbots, and the importance of empathy and transparency in mental health counseling. Don't miss this valuable perspective on a critically important dimension of healthcare that's informed by decades of experience as a clinician, government official and global advocate. Mentioned in this episode:The Behman HospitalMaadi Psychology Center If you like this podcast, please share it on your social channels. You can also subscribe to the series and check out all of our episodes at www.osmosis.org/podcast
We're discussing Raising the Bar in Value Based Primary Care Payment! Faisel and Dan are joined by Purva Rawal, PhD, Former Chief Strategy Officer, CMS Innovation Center at Centers for Medicare & Medicaid Services.Our conversation revolves around navigating changing healthcare policies, unlearning fee for service as the default, and leveraging community relationships within alternative care models.
In this episode, we look at new research on mucoactive therapy for bronchiectasis, aspirin use in anticoagulated patients with coronary disease, and sotatercept for early pulmonary arterial hypertension. We explore the genetics behind misdiagnosed common diseases and review uncertainty in medical training. We also share a case of woman with abdominal distention, edema, and pleural effusions and Perspectives on sickle cell disease, fetal personhood, and living with a genetic diagnosis.
LOOKING FOR AFFORDABLE HEALTHCARE? We are hearing a lot about how Obamacare subsidies are going away and that people won't be able to afford health insurance, but there are options! I've had Travis Bockenstedt from Pinnacle Advanced Primary Care on the show many times, but today he is joined by CEO Lisa Fagan from Smith Medical Direct Specialty Care to talk about how direct services can save you big. If you're losing your subsidy you want to pay attention to this! If you self insure, you want to pay attention to this! Find out more about Pinnacle here, or Smith Medical here.
Podcast host Lisa Rosenbaum talks with Steven Lin, a Stanford PCP and AI implementation expert, about the promise and perils of AI and its limits as a solution to the forever crisis of primary care. A full transcript of this episode is available at https://www.nejm.org/doi/full/10.1056/NEJMp2514233.