Podcasts about Multiple sclerosis

Pentagon plans widespread testosterone screening for troops; New study claims arthroscopic surgery for age-related degenerative changes of knees is worthless; Widely touted “precision” proton therapy doesn't outperform conventional radiation treatment for prostate cancer; Comparing the effectiveness of gummies and liquids vs. tablet or capsule forms of supplements; Supplements to lower LDL; Lithium orotate for Alzheimer's prevention; Novel ultrasound treatment may target inflammation in osteoarthritis; Researchers explore antiviral treatments for multiple sclerosis.  

Panelists: Josh Anderson, Belva Smith and Brian Norton ATFAQ205: Q1. Multiple Sclerosis and office work, Q2. Sensory tools for loud environments, Q3. Screen Mag and accessibility tools for the computer, Q4. TBI memory and organizational tools, Q5. Future of autonomous transportation

Send us Fan MailThis week on Just MS News, we examine new research that may help clarify how Epstein–Barr virus fits into the immune process behind multiple sclerosis.We also look at evidence supporting earlier high-efficacy treatment for pediatric-onset MS, the DOT-MS trial on stopping treatment after years of stable disease, virtual-reality rehabilitation for cognitive symptoms, and a Colorado community story about mobility, rehabilitation and assistive technology.This episode covers:• A more specific EBV-reactive T-cell response identified in people with untreated MS• Earlier high-efficacy treatment and long-term disability outcomes in pediatric MS• What happened when people with stable MS stopped certain disease-modifying therapies• Virtual-reality rehabilitation for cognition and mood• A bride with MS who prepared for a supported 68-foot aisle walkArticles and ResearchCD4+ T Cells Reactive to Epstein–Barr Virus Late Lytic Antigens Are Enriched in Individuals With Multiple SclerosisSource: Science Translational MedicineAuthors: Kjetil Bjornevik and colleaguesRead the studyEarly High-Efficacy Therapy May Reduce Disability in Pediatric MSSource: Neurology AdvisorBased on research published in NeurologyRead the articleDiscontinuation of Disease-Modifying Therapy in Patients With Stable Multiple Sclerosis—Clinical Trial of the YearSource: JAMA NeurologyAuthor: S. Andrew Josephson, MDRead the editorialDiscontinuation of First-Line Disease-Modifying Therapy in Patients With Stable Multiple Sclerosis: The DOT-MS Randomized Clinical TrialSource: JAMA NeurologyAuthors: Eline M. E. Coerver, Wing Hee Fung, Janet de Beukelaar and colleaguesRead the original trialEffects of Virtual Reality-Based Rehabilitation on Cognitive Function and Mood in Multiple Sclerosis: A Systematic Review and Meta-Analysis of Randomized Controlled TrialsSource: Multiple Sclerosis and Related DisordersAuthors: Jiongliang Zhang, Minmin Wu, Jinting Li, Wenjing Song, Xiaoguang Lin and Luwen ZhuRead the study on PubMedColorado Bride With MS Surprises Wedding Guests by Walking Down the AisleSource: 9NEWS ColoradoRead the storyVisit Just Multiple Sclerosis for the complete weekly digest:https://justmultiplesclerosis.comSubscribe for calm, clear and accessible weekly MS news without the information overload.#MultipleSclerosis #MSNews #JustMSNews #MSResearch #EpsteinBarrVirus #PediatricMS #MSRehabilitationThe Just MS (Multiple Sclerosis) Show, w host Justin Loizos, is a podcast that connects, educates and tries to uplift others living with multiple sclerosis. It provides real-life stories, interviews, and information about DMTs (disease modification therapies) and updates on research developments.www.justmultiplesclerosis.com

Where someone lives can profoundly influence their multiple sclerosis journey. While advances in diagnosis and treatment have transformed MS care in many parts of the world, millions of people still face significant barriers to diagnosis, specialist care and life-changing therapies. In this episode of the ECTRIMS Podcast, host Brett Drummond speaks with Dr. Fiifi Duodu and Prof. Alfredo Damasceno about the realities of managing MS patients in diverse healthcare settings and what can be done to improve equity worldwide. Together, they discuss:

Dr. David Chernoff, Chief Medical Officer of Setpoint Medical, discusses electrically driven vagus nerve stimulation (VNS) as a “neuroimmune modulation” approach to autoimmune and inflammatory disease. Chernoff explains the vagus nerve's sensory role in monitoring organs and signaling the brainstem and spleen to regulate immune responses, and how precise stimulation can reduce pro-inflammatory cytokines without immunosuppression. Setpoint's miniaturized, wireless, MRI-compatible implant is placed in an outpatient 45-minute neck procedure and delivers one minute of daily stimulation titrated to an upper comfort level; long-term safety is supported by prior surgical experience and a 242-patient blinded RA study with two-year data, leading to FDA approval for rheumatoid arthritis. The discussion covers add-on use with medications, potential steroid tapering, reimbursement, and research in Crohn's disease, relapsing MS (vision and remyelination), and other conditions, including psoriatic arthritis, lupus, and neurodegenerative diseases.

Dr. Hoffman continues his conversation with Dr. David Chernoff, Chief Medical Officer of Setpoint Medical.

Living with depression has been described as "like living under a wet, heavy blanket". It can stop someone from showing up at work, meeting up with friends, and even connecting with their family.  One out of every two people living with MS will experience depression at some point in their MS journey. The METS for MS study is focused on a novel approach to treating major depressive disorder among people with MS -- one that doesn't require another infusion, injection, or pill. This week, Dr. Robert Motl, principal investigator for the METS for MS study, joins us to explain what the study is about and what his team is learning.  And Kelly, who lives with progressive MS, joins us to share how her participation in the study became life-changing.  We'll also tell you about the $500,000 donation to MS research that Fernando Mendoza and his family just made. We're sharing the details about the CAR-NKT cell therapy for MS that's being developed at UCLA. You'll learn about the novel nanoparticle therapy for MS that's being developed by a team at Syracuse University's BioInspired Institute. And we're sharing the surprising results of a study that measured the effectiveness of Rituximab versus Ocrevus.  We have a lot to talk about! Are you ready for RealTalk MS??! This Week: A study focusing on a novel approach to treating MS-related depression  :22 Fernando Mendoza and his family donate $500,000 to MS research  1:18 UCLA research team receives a $7.49 million dollar grant to develop CAR-NKT therapy for MS  2:22 Syracuse University research team receives NIH grant to develop novel nanoparticle therapy for MS   6:22 Study results: Rituximab and Ocrevus were compared head-to-head and the results are surprising   9:43 Dr. Robert Motl explains the Mood and Exercise Training Study for Multiple Sclerosis, and Kelly explains how her participation in the study turned out to be life-changing  14:22 Share this episode  35:43 Next week  36:03 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/463 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes at www.RealTalkMS.com STUDY: Rituximab versus Ocrelizumab in Newly Diagnosed Relapsing Multiple Sclerosis https://www.nejm.org/doi/10.1056/NEJMoa2600993 PARTICIPATE: Mood and Exercise Training Study for Multiple Sclerosis (METS for MS) Email: METSforMS@uic.edu  Phone Ariel: (312) 355-1790 JOIN: The RealTalk MS Facebook Group https://facebook.com/groups/realtalkms REVIEW: Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on X, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 463 Guest: Dr. Robert Motl, Kelly Privacy Policy

Dr. Bill Andrews is the Founder and CEO of Sierra Sciences; a company focused on finding ways to extend human lifespan and health span. Bill has been featured in Popular Science, The Today Show, The Doctor's TV Show, and numerous documentaries on the topic of life extension. Bill co-stars with Dr. Aubrey de Grey in the documentary “The Immortalists” that made it to the “Top-10-List” to receive an Oscar in 2014Bill is also an ultramarathon runner with over 100 ultramarathons under his belt. Bill believes that consistent and fun endurance exercise is one of the best ways to reduce inflammation and slow aging.Speaking at the Cell Surgical Conference 2024Bill's areas of research have included Dwarfism, Cancer, CardiovascularDisease, Inflammation, Osteoporosis, Anemia, Multiple Sclerosis,Aging, and many others. Before founding Sierra Sciences Bill was aMedical Researcher at Armos Corporation, Codon Corporation, BerlexBiosciences, Geron Corporation, and EOS Biotech. Bill played key rolesin the discoveries and inventions of:Human Growth Hormone (hGH), Prorennin (Prochymosin), Tissue Plasminogen Activator(tPA), Osteo-Inductive Factor (OIF), Thrombomodulin, Erythropoietin (EPO), Beta-Seron, HTSite Specific Mutagenesis, Various Cancer Treatments (Rytelo, Telomelysin, GV1001, UV1,mutant hTR, and others), Telomerase, TRAPeze, TA-65, hTERT mRNA RT-PCR HTS,Telomerase Gene Therapy, C0314818 (TAM818), TeloSMRT, Isagenesis (Product B), Premere, Telo-Vital, Rytelo, and many more.In 1997 Bill was awarded 2nd Place as National Inventor of the Year for his cancer research. In the early-to-mid 1990s, while at Geron Corporation, Bill led the research to discover both the RNA and protein components of human telomerase, the enzyme responsible forpreventing telomeres from shortening in our reproductive cells. He has determined that the only real definite “hard-stop” to lifespan and health span, that is true for all humans, as well as non-human primates, cats, dogs, horses, sheep, pig, and deer, is “Telomere Shortening”. No matter what else we do to treat aging, aging will neverbe cured and/or reversed unless we also solve the telomere shortening problem.Presently, the primary focus of Sierra Sciences is to find ways toproduce telomerase and lengthen telomeres in all cells of the humanbody, not just our reproductive cells, and eliminate this key hard-stop tosuper-longevity. But Bill is aware that the war against aging is not goingto be won with just one battle.Contact Dr. Bill Andrews:website: https://sierrasci.com/https://www.facebook.com/telomere.bill.andrewshttps://www.facebook.com/profile.php?id=61551532301673linkedin.com/in/billandrewsphdhttps://www.youtube.com/@billandrewsphdhttps://www.youtube.com/@sierrasciences1625https://www.instagram.com/yonderssi/Dr. Kimberley LinertSpeaker, Author, Broadcaster, Mentor, Trainer, Behavioral OptometristEvent Planners- I am available to speak at your event. Here is my media kit: https://brucemerrinscelebrityspeakers.com/portfolio/dr-kimberley-linert/To book Dr. Linert on your podcast, television show, conference, corporate training or as an expert guest please email her at incrediblelifepodcast@gmail.com or Contact Bruce Merrin at Bruce Merrin's Celebrity Speakers at merrinpr@gmail.com702.256.9199Host of the Podcast Series: Incredible Life Creator PodcastAvailable on...Apple: https://podcasts.apple.com/us/podcast/incredible-life-creator-with-dr-kimberley-linert/id1472641267Spotify: https://open.spotify.com/show/6DZE3EoHfhgcmSkxY1CvKf?si=ebe71549e7474663 and on 9 other podcast platformsAuthor of Book: "Visualizing Happiness in Every Area of Your Life"Get on Amazon: https://amzn.to/4cmTOMwWebsite: https://linktr.ee/DrKimberleyLinertThe Great Discovery eLearning platform: https://thegreatdiscovery.com/kimberleyl

Send us Fan MailThis week on the Just MS Show, we look at five important multiple sclerosis stories.Researchers used artificial intelligence to identify gray matter lesions that can be difficult to see on standard MRI scans. We also examine a head-to-head trial comparing rituximab with Ocrevus in newly diagnosed relapsing MS.Other stories include the completion of enrollment in a nasal foralumab trial for non-active secondary progressive MS, early research into how myelin damage may affect brain activity during sleep, and a $500,000 gift supporting MS research from Las Vegas Raiders quarterback Fernando Mendoza and his family.The Just MS Show delivers calm, clear and accessible MS news without hype or information overload.Show NotesAI reveals previously hidden gray matter lesions in MSResearchers developed an artificial intelligence method that can identify cortical lesions that are often difficult to see on conventional MRI scans.Read the article from News-MedicalRituximab compares closely with Ocrevus in early relapsing MS trialThe OVERLORD-MS trial compared rituximab with Ocrevus in people with newly diagnosed relapsing MS and found rituximab was noninferior for preventing new or enlarging MRI lesions during the study period.Read the article from Conexiant NeurologyFinal participant begins treatment in nasal foralumab trial for non-active SPMSEnrollment is complete in the Phase 2 INFORM-MS trial studying intranasal foralumab in people with non-active secondary progressive MS. Full safety and effectiveness results have not yet been released.Read the article from NR TimesMyelin damage may alter brain rhythms during sleepEarly research suggests that damaged myelin may affect electrical brain activity during sleep. The strongest evidence currently comes from animal research, with further human studies still needed.Read the article from News-MedicalMendoza family presents $500,000 gift for MS researchLas Vegas Raiders quarterback Fernando Mendoza and his family formally presented a $500,000 gift supporting MS research at the University of Miami in honour of his mother, Elsa, who lives with MS.Read the article from 8 News NOWLinksJust MS News:https://www.justmultiplesclerosis.comPodcast page:https://www.justmultiplesclerosis.com/podcastWeekly news archive:https://www.justmultiplesclerosis.com/archiveThe Just MS (Multiple Sclerosis) Show, w host Justin Loizos, is a podcast that connects, educates and tries to uplift others living with multiple sclerosis. It provides real-life stories, interviews, and information about DMTs (disease modification therapies) and updates on research developments.www.justmultiplesclerosis.com

It's episode 174, Veronica & Laurie chat writing and publishing, share news and events, including Bernadette Eden telling us all about 'Queens of the Desert', this year's Romance Writer's Australia conference. Laurie shares her great feedback on Alan Baxter's Write the Fight Right Workshop, and we sneak a peak at next month's book giveaways. Plus Laurie has a fabulous with 'debut' romance author, Bride Blake.Book spotlights:1. Might Cry Later by Kay Kerr – rom com2. My Invisible Battle with Multiple Sclerosis by Shruti Ghate – memoir3. The Case of the Hydegild Sacrifice by David Cairns – historical mystery4. The Battle for Victoria Street by Gabiann Marin – middle grade5. The Truth About Love by Mark Worthington – non-fiction6. Midnight Angel by Kevin Klehr – urban fantasy7. Three Ghosts by Kevin Klehr – urban fantasyIntro - 0:57News - 08:34Book spotlights - 25:18Author interview - 44:38Post interview chat - 1:31:14Quotes - 1:33:17Support the showThanks for listening.Visit australianbooklovers.com to learn more.

Welcome to the NeurologyLive® Mind Moments® podcast. Tune in to hear leaders in neurology sound off on topics that impact your clinical practice.In this Mind Moments episode, Daniel Ontaneda, MD, PhD, professor of neurology at the Cleveland Clinic Mellen Center for Multiple Sclerosis, discusses a recently published study in Neurology evaluating the application of the 2024 McDonald Criteria in individuals with nonspecific neurologic symptoms or incidental MRI findings. Using data from the CAHPS-MS study, Ontaneda explains how the revised diagnostic criteria perform in these previously understudied patient populations and what the findings may mean for earlier identification of multiple sclerosis. The conversation explores the rationale behind expanding the 2024 McDonald Criteria, the role of central vein sign and cerebrospinal fluid oligoclonal bands in improving diagnostic confidence, and how clinicians should approach patients who fall into a diagnostic gray zone. Ontaneda also discusses the practical application of the updated criteria, the importance of longitudinal follow-up, and how emerging biomarkers may continue to refine MS diagnosis in the years ahead.  Looking for more Multiple sclerosis & demyelinating disorders discussion? Check out the NeurologyLive® Multiple sclerosis & demyelinating disorders clinical focus page.Episode Breakdown: 1:15 – Why the 2024 McDonald Criteria expanded diagnostic eligibility 4:30 – Applying the criteria in nonspecific symptom presentations 6:20 – Clinical relevance of symptom patterns and MRI findings 8:40 – Using biomarkers to improve diagnostic confidence 11:25 – Neurology News Minute  13:55– Interpreting dissemination in time with updated criteria 15:45 – Future validation of emerging MS diagnostic biomarkers The stories featured in this week's Neurology News Minute, which will give you quick updates on the following developments in neurology, are further detailed here: FDA Advisory Committee Schedules Meeting to Review Deramiocel's BLA in Duchenne Muscular Dystrophy FDA Clears PoNS Device for Stroke Rehabilitation, Expanding Neurostimulation Beyond MS Indication FDA Accepts Sarepta's sNDAs for Casimersen and Golodirsen for Duchenne Muscular Dystrophy Thanks for listening to the NeurologyLive® Mind Moments® podcast. To support the show, be sure to rate, review, and subscribe wherever you listen to podcasts. For more neurology news and expert-driven content, visit neurologylive.com.

Pointing to Edward's first symptom of Relapse–Remitting MS is tricky. From anxiety in his 20s, to poor sleep and numb hands, to back pain and difficulty walking, the road to diagnosis has been rocky. When he finally received confirmation—in the form of a terrifying MRI showing countless lesions on his brain and spine—Edward was a new father in his early 30s. Coming to terms with a lifelong condition that presents differently for everyone was a process that has slowly shifted his outlook on both his past and his future. In this episode, we speak with Edward about what his journey through symptoms and diagnosis looked like, and reflect on how facing down a debilitating illness can change your outlook on life if you let it. A musician from a young age, today Edward is exploring live performance with his solo project, Green Plastic Whistle, and facing an aversion to fame that derailed some previous opportunities. As he puts it, being told you have an unpredictable disease, that has the potential to impact anything from bladder function to your ability to see, really puts fear into perspective. With cautious optimism and a balanced take on the pros and cons of the medical system, Edward and Jesse delve into how you envision your future when you don't know what your health will hold. They explore the promising remyelination medications that have the MS community abuzz and what it's like to start a family in the midst of disease progression. Edward's experience with Multiple Sclerosis has given him a new perspective on how we prioritize our lives and what's possible when you begin to face the future without fear. Learn more about Edward's solo project, Green Plastic Whistle:  https://www.instagram.com/greenplasticwhistle/  Listen to Green Plastic Whistle on Spotify: https://open.spotify.com/user/0b6gv1y0qrwlp4bp3ztmusnsa?si=d557f3eb1a0947c2 https://www.youtube.com/watch?v=hV_reArTc7g Watch the episode on YouTube or Spotify, listen here on our website or on your favorite podcast platform. PODCAST LINKSWEBSITE: https://majorpainpodcast.comEMAIL: majorpainpodcast@gmail.comSUBSCRIBE: https://majorpainpodcast.com/subscribeSPOTIFY: https://open.spotify.com/show/5NDoD07WJmICdfdRKq0TyNAPPLE PODCASTS: https://podcasts.apple.com/us/podcast/major-pain/id1562947550?mt=2&ls=1 SOCIAL MEDIAINSTAGRAM: https://www.instagram.com/majorpainpodcastTIKTOK: https://www.tiktok.com/@majorpainpodcastYOUTUBE: https://www.youtube.com/@MajorPainPodcastFACEBOOK: https://www.facebook.com/majorpainpodcast AFFILIATE LINKSRARE PATIENT VOICE: https://rarepatientvoice.com/MajorPainPodcastAMAZON SHOP: https://www.amazon.com/shop/majorpainpodcastNEURAHEALTH: https://www.neurahealth.co/majorpain

Today, I am talking to Liz Bentley, psychotherapist, writer, comedian, poet and performer. Liz has recently released her brand NEW memoir; The Suicidal Therapist, Confessions of a Wounded Healer on Survivors Voices Press. This is her heartfelt and authentic story, diving into some of the aspects of mental health that we often don't talk about. Liz sought therapy in her early twenties, whilst dealing with problems with bulimia, intimate relationships, drugs, grief and being diagnosed with Multiple Sclerosis. She talks candidly about these subjects in her book. Liz has worked extensively for over thirty-four years as a psychotherapist, supervisor and facilitator in the NHS, Goldsmiths College, Lewisham College (in London) and private practice. Liz has performed with her comedy poetry at The Poetry Cafe, London Literature Festival, Leicester Square Theatre, Edinburgh Festival, The Ivy House and many other festivals and venues. In the episode today, Liz is going to dive into her life journey, taking us behind the scenes of her imperfect, complicated, persevering and vibrant path. It's an honest and frank conversation to inspire hope and encouragement to anyone who is struggling today. You can order a copy of Liz's book at Survivor's Press https://survivorsvoices.org/survivors-voices-press/ and also from Amazon https://www.amazon.co.uk/Suicidal-Therapist-Confessions-Wounded-Healer-ebook/dp/B0GC9LS63N Liz's website: https://lizbentley.co.uk/  

On this episode of the podcast, we are joined by BJJ Black Belt and UFC veteran Professor Alberto Crane. Professor Crane discusses his start in BJJ in 1994 and eventually transitioning to fighting in early MMA events starting at King of the Cage, old school training in the 1990's, the evolution of BJJ in MMA, the evolution of BJJ in sport jiu-jitsu, how to make sport BJJ more exciting, overcoming his early struggles in BJJ competition, how to transfer success in the gym to success in tournaments, training for longevity, how getting diagnosed with Multiple Sclerosis has impacted his life, and Professor Crane's book titled "All In." You can check out his book here: All In: Lessons On and Off The Mat Thanks to the podcast sponsors: Datsusara, head over to https://www.dsgear.com/ and use the code Chewjitsu10 to get 10% off of the highest quality hemp gear for BJJ. Check out "Athlethc" at https://athlethc.com/ and use the code Chewjitsu10 to get 10% off of your order of hemp-derived THC performance mints.  Charlotte's Web CBD. Head over to https://bit.ly/chewjitsu30 and use the promo code Chewjitsu30 to get 30% off of your total purchase. Epic Roll BJJ. Check out https://epicrollbjj.com/ and use the promo code Chewjitsu20 to get 20% off of your total purchase. Check out podcast exclusives including conversations with guests, Q&A sessions, and tons more at https://patreon.com/thechewjitsupodcast

Send us Fan MailThis week's Just MS News starts with two stories from the same MS brain-donor study, looking at why progression can differ so much from person to person. We also cover MS Copilot and digital disability monitoring, research into fat-filled immune cells called foamy microglia, an experimental brain implant for speech loss, and Spain's “Get Wet for MS” campaign supporting neurorehabilitation and research.As always, this update is designed to give the MS community one calm place to catch up on the week's most relevant news without hype or overload.Live article linksLarge multiple sclerosis brain cohort reveals biological differences linked to disease severity https://medicalxpress.com/news/2026-06-large-multiple-sclerosis-brain-cohort.htmlBrain Tissue Patterns and Genetics Drive MS Progression https://neurosciencenews.com/multiple-sclerosis-progression-genetics-30961/EAN 2026: MS Copilot shows promise in monitoring disability progression in MS https://www.clinicaltrialsarena.com/analyst-comment/ean-2026-ms-copilot-shows-promise-in-monitoring-disability-progression-in-ms/Fat-filled immune cells may help explain why some MS progresses faster https://www.diabetes.co.uk/news/2026/jul/fat-filled-immune-cells-may-help-explain-why-some-ms-progresses-faster.htmlNew brain implant could restore communication for people with speech loss https://www.news-medical.net/news/20260629/New-brain-implant-could-restore-communication-for-people-with-speech-loss.aspxPromote neurorehabilitation and research, challenges of “Mójate por la Esclerosis Múltiple” 2026 https://www.democrata.es/en/health/promote-neurorehabilitation-and-research-challenges-of-mojate-por-la-esclerosis-multiple-2026/The Just MS (Multiple Sclerosis) Show, w host Justin Loizos, is a podcast that connects, educates and tries to uplift others living with multiple sclerosis. It provides real-life stories, interviews, and information about DMTs (disease modification therapies) and updates on research developments.www.justmultiplesclerosis.com

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/PFX865. CME/MOC/AAPA/IPCE credit will be available until June 27, 2027.New Pathways, New Possibilities in Multiple Sclerosis: BTK Inhibition and the Future of Patient Care In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Genentech, a member of the Roche Group.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/PFX865. CME/MOC/AAPA/IPCE credit will be available until June 27, 2027.New Pathways, New Possibilities in Multiple Sclerosis: BTK Inhibition and the Future of Patient Care In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Genentech, a member of the Roche Group.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/PFX865. CME/MOC/AAPA/IPCE credit will be available until June 27, 2027.New Pathways, New Possibilities in Multiple Sclerosis: BTK Inhibition and the Future of Patient Care In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Genentech, a member of the Roche Group.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/PFX865. CME/MOC/AAPA/IPCE credit will be available until June 27, 2027.New Pathways, New Possibilities in Multiple Sclerosis: BTK Inhibition and the Future of Patient Care In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Genentech, a member of the Roche Group.Disclosure information is available at the beginning of the video presentation.

Jamie Lynn Sigler grew up in front of the world as Meadow Soprano, one of television's most iconic daughters. But while she was coming of age on screen, she was privately carrying a secret that almost nobody knew: at age 20, she was diagnosed with multiple sclerosis. For 14 years, she hid her diagnosis from Hollywood, her coworkers, and her friends out of fear and shame. Now, Jamie sits down with Hoda Kotb to pull back the curtain on a life no longer built on perfection, but on radical honesty. She opens up about her deeply moving memoir, And So It Is, which begins with a terrifying medical crisis involving her young son, Beau. Jamie shares how she broke through the paralyzing loop of childhood trauma through EMDR therapy, what it was like to finally confide in her late co star James Gandolfini, and how she found peace by letting go of the need to pretend she was always fine. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Sarah Thomas is a force of nature. As Strategic Partnerships and Programs Manager at The Venture Center in Little Rock, she helps entrepreneurs at every stage find their footing — from building a first website to navigating complex government contracts. But that's just one of her many hats. She's also a published author, a yoga instructor, president of Women in Tech Central Arkansas, and a woman living with Multiple Sclerosis who refuses to let any of it slow her down.In this episode, we cover:What The Venture Center is and how it supports entrepreneurs in Arkansas Their 12-week program for veteran-owned businesses, connecting vets with SBA resources, attorneys, marketing pros, and moreArkansas's emerging role as a lithium hub — what's happening in South Arkansas, who's involved (think Standard Lithium, Exxon, Tetra, and others), and what it could mean for jobs, schools, and communities statewideSarah's book, Chair Yoga for Multiple Sclerosis and Chronic Pain, available now at Barnes & Noble, Amazon, and WalmartHow her yoga mindset shows up in her work with entrepreneurs: breathe, get present, focus on what you can do todayWhat it's like being the only woman — and often the only woman of color and person with a disability — in high-level rooms, and how she handles itHer advice for women and girls interested in STEM: always be a student, find mentors, and then turn around and teachResources mentioned:The Venture Center: venturecenter.coWomen in Tech Central Arkansas (sponsored by Google and Walmart)National MS SocietySarah's mantra: Don't waste your breath on negativity. Use it for positivity. Be your own hero.

"Sometimes the best medical news isn't dramatic. Sometimes it's hearing one simple word: Stable." Continuing our previous conversation about Multiple Sclerosis progression and reclassification, we're back with the update we'd been hoping to share. After meeting with our neurologist, reviewing MRI results, and establishing care with a new primary care provider, we're reflecting on what stability really means after living with Multiple Sclerosis for decades and why "stable" can be one of the most encouraging words you'll ever hear. We also talk about rebuilding strength after setbacks, why physical therapy still matters, and the importance of finding healthcare providers who truly listen. In this episode, we discuss: The relief of hearing "no new lesions" after an MRI. Why rebuilding strength after surgery and deconditioning takes patience. How living with MS doesn't mean ignoring the rest of your health. Why finding healthcare providers who listen and partner with you makes all the difference. How physical therapy, exercise, and adaptive equipment continue to play important roles in our lives. Why we're choosing to move forward rather than living in fear as we continue aging with Multiple Sclerosis. We also explore why building strong relationships with your neurologist and primary care provider can make a tremendous difference throughout your MS journey. We'd love to hear from you What makes a great neurologist or healthcare provider in your experience? Have you ever changed doctors because you weren't being heard? Or have you found a physician who has made all the difference in your MS journey? Share your thoughts in the comments or connect with us through our website or Email Thank you for listening to A Couple Takes on MS. We're grateful you're moving forward with us one step, one roll, and one story at a time. *** Remember to rate, review, and subscribe to A Couple Takes on MS Podcast for two insightful perspectives on this one multifaceted disease.

Lina Nielsen is an Olympic sprinter and hurdler who has overcome incredible challenges to reach the top of her sport.Growing up in East London, Lina got the chance to be a kit carrier at the London 2012 Olympic Games. Seeing the world's greatest athletes up close made her dream of competing in the Olympics one day too. But when she was just 17, Lina was diagnosed with Multiple Sclerosis after the right side of her body became paralysed. She thought her Olympic dream was over. It wasn't. In our conversation, Lina shares how she defied the odds to achieve her dreams, what it took to get there and what she's aiming for next. In this episode, Lina shares:Her incredible journey to Olympic bronze Growing up without her dad and its impact on her relationshipsBeing diagnosed with MS at 17 The misconceptions about MS she's determined to break downLearning to accept her diagnosis without letting it define herLina's story is a powerful reminder that the labels we're given don't define what's possible.Lina Nielsen is Great Company.Lina will be competing in the Birmingham 2026 European Athletics Championships in August. You can buy tickets HERE! https://tickets.birmingham26.com/If you enjoyed the show, you can also follow us: Instagram- @greatcompanypodcastTikTok - @greatcompanypodcast Jamie - @jamielaingAnd if you've got thoughts, questions and comments, you can email us at: greatcompany@jampotproductions.co.ukTHE CREDITSProducers: Helen Burke & Dan KingAssistant Producer: Issy Weeks-HankinsVideo: Josh BennettSenior Social Media Manager: Laura CoughlanAudio: Rafi Amsili GeovannettiExecutive Producer: Ewan Newbigging-ListerGreat Company is an original podcast from JamPot. Hosted on Acast. See acast.com/privacy for more information.

Our guest this week is Jamie Bark, of New Ricchmond, WI, a fire fighter, former owner of Value Auto Glass, a widower and father of two daughters, including one with Spinal Muscular Atrophy.Jamie and his wife, Jackie, were married for 30 years, before she very sadly passed away in January of 2025 after a long battle with Multiple Sclerosis.  He is also the proud father of two daughters: Maddie (21) and Gabby (17) who has a type of Muscular Dystrophy known as Spinal Muscular Atrophy (SMA) level 2. Jamie reflects on his life as a firefighter and private business owner, the struggles of raising a child with SMA, losing his wife to a debilitating disease and becoming a sole parent as well as the role Cure SMA and MDA have played on behalf of his family. Jamie's story speaks volumes about his commitment to family, perseverence and reslience all on this episode of the sFN Dad To Dad Podcast. Show Notes - Phone – (715) 222-0369Email – valueglassco@gmail.comLinkedIn - https://www.linkedin.com/in/jamie-bark-74631022/MDA – https://www.mda.org/Cure SMA - https://www.curesma.org/SFN Audiobook 'On Losing A Child' - https://tinyurl.com/46jueh3s Special thanks to all those who supported the SFN U.S. Tour, a month-long, 50-state, 60+ stop tour that took place from May 21 to June 21, 2026: to strengthen and grow the Special Fathers Network and distribute 1,000 complimentary copies of our new book: Dads Raising Children With Special Needs & Disabilities: A Guide For 21st Century Dads. Special Fathers Network –SFN is a dad to dad mentoring program for fathers raising children with special needs. Many of the 800+ SFN Mentor Fathers, who are raising kids with special needs, have said: “I wish there was something like this when we first received our child's diagnosis. I felt so isolated.  There was no one within my family, at work, at church or within my friend group who understood or could relate to what I was going through.”SFN Mentor Fathers share their experiences with younger dads closer to the beginning of their journey raising a child with the same or similar special needs. The SFN Mentor Fathers do NOT offer legal or medical advice, that is what lawyers and doctors do. They simply share their experiences and how they have made the most of challenging situations.Check out the 21CD YouTube Channel with dozens of videos on topics relevant to dads raising children with special needs - https://www.youtube.com/channel/UCzDFCvQimWNEb158ll6Q4cA/videosPlease support the SFN. Click here to donate: https://21stcenturydads.org/donate/Special Fathers Network: https://21stcenturydads.org/  

As a country, we're living longer than ever before. The average life expectancy in the United States is now 79 years old, according to the Centers for Disease Control. But how are we doing when we get to our golden years? In Ohio, the answer is not necessarily the best, according to the latest America's Health Rankings Senior Report. This study from The United Health Foundation ranked Ohio 36th in the country in overall health for seniors. Some major concerns include suicide rates, drug related deaths, poverty and food insecurity concerns and levels of physical activity. When you add in concerns about mental function and emotional wellbeing, there's a lot to think about as we age. On Tuesday's edition of the "Sound of Ideas," we're looking at what we can do in our younger years to try to maintain our mental, emotional and physical health for as long as our bodies will let us. Guests: - Gary Grosel, M.D., Chief Medical Officer, UnitedHealthcare of Ohio - Lester Carney, age 92, Olympic athlete who won a silver medal in the 200-meter dash at the 1960 Summer Olympics in Rome, Italy - Robert Bermel, M.D., Staff Neurologist, Neurological Institute's Mellen Center for Multiple Sclerosis at Cleveland Clinic - Roopa Anmolsingh, M.D., Lead Geriatrician for Community Programs, Cleveland Clinic

Next week, Matt Knaggs and Colin Goodman will attempt to set a Guinness World Record for running the 350-mile length of Ireland with MS. This week, you'll meet Matt and Colin and learn why this undertaking is so important to each of them.  We're also sharing survey results that point to gaps in how we approach MS care from the day of diagnosis. We'll tell you what it really means when you read that the prevalence of MS is increasing. It isn't bad news at all! We'll provide you with all the details you need to register for ECTRIMS Patient Community Day. And, if you can spare 20 minutes, we'll tell you how you can participate in an MS research study from the comfort of your own home. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: We're hitting the open road in Ireland with Matt Knaggs and Colin Goodman  :22 Survey points to gaps in how we approach MS care from day one  2:48 What does the increase in MS prevalence really mean?  8:48 Register for ECTRIMS 2026 Patient Community Day  12:33 An opportunity for you to participate in MS research without leaving home   14:10 Matt Knaggs and Colin Goodman talk about their attempt to set a Guinness World Record for running the length of Ireland with MS  15:56 Share this episode  32:13 Next week  32:33 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/460 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes at www.RealTalkMS.com STUDY: Understanding the Unmet Needs of People with MS at Diagnosis and Throughout Their Care Journey: Insights from a Survey-Based Study https://link.springer.com/article/10.1007/s40120-026-00942-y STUDY: Drivers of Prevalence in Major Motor Neurodegenerative Diseases: Temporal Trends in Sweden and France (2003-2022) https://www.neurology.org/doi/10.1212/WNL.0000000000218072 REGISTER: ECTRIMS 2026 Patient Community Day https://www.ectrimspatientcommunity.eu PARTICPATE IN RESEARCH: Survey: Automatic and Reflective Determinants, Fatigue, and Physical Activity for People with Multiple Sclerosis https://purdue.ca1.qualtrics.com/jfe/form/SV_douenJftXAcGxVk JOIN: The RealTalk MS Facebook Group https://facebook.com/groups/realtalkms REVIEW: Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on X, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 460 Guest: Matt Knaggs, Colin Goodman Privacy Policy

Selena Freisens, Head of Global Medical Affairs at Merz Therapeutics, is focused on increasing access to tools to support neurological health. They have developed a digital app iFlexo, which is designed to provide at-home physiotherapy for stroke survivors.  The app has been tested in Nigeria and Sierra Leone in partnership with the World Stroke Organization and is designed to operate offline as well, to serve users in rural areas with limited internet connectivity. Selena explains, "Our company is family-owned and in its fifth generation, so we have a rather long-term legacy, and the newer part is Merz Therapeutics, and our focus in Merz Therapeutics is on neuroscience. So we practically cover the number of movement disorders such as Spasms, Dystonias. We also have a focus on Parkinson's and Multiple Sclerosis."   "We continuously work on building this awareness and knowledge. One example is Parkinson's disease. And when I started working with Parkinson's disease, most of the patients would have off episodes, which are exacerbations of their symptoms, but many of these off episodes are underdiagnosed, and they're not really treated optimally. So it's really a lot of attention is needed to educate not only HCPs and, of course, some other stakeholders, but particularly patients."   "So the time also matters for stroke survivors. So it's very important that they start as soon as possible all the therapies, but also the physiotherapy at the same time. What this digital tool does is give two options. One is education on the one side, and on the other hand, a guided exercise that will enable people and stroke survivors to exercise at home. And with that, obviously, the personalized goals have been worked out together with the experts and HCPs so that they can achieve those goals faster, while working from home." #MerzTherapeutics #StrokeRehab #DigitalHealth #NeuroRehab #AccessToHealth #WorldStrokeOrganization #Physiotherapy #HealthEquity #TeleRehab #HCPs #Africafirst #AccesstoHealth #EquitableAccess #PostStrokeRehabilitation #PatientDrivenInnovation Merztherapeutics.com Listen to the podcast here

Selena Freisens, Head of Global Medical Affairs at Merz Therapeutics, is focused on increasing access to tools to support neurological health. They have developed a digital app iFlexo, which is designed to provide at-home physiotherapy for stroke survivors.  The app has been tested in Nigeria and Sierra Leone in partnership with the World Stroke Organization and is designed to operate offline as well, to serve users in rural areas with limited internet connectivity. Selena explains, "Our company is family-owned and in its fifth generation, so we have a rather long-term legacy, and the newer part is Merz Therapeutics, and our focus in Merz Therapeutics is on neuroscience. So we practically cover the number of movement disorders such as Spasms, Dystonias. We also have a focus on Parkinson's and Multiple Sclerosis."   "We continuously work on building this awareness and knowledge. One example is Parkinson's disease. And when I started working with Parkinson's disease, most of the patients would have off episodes, which are exacerbations of their symptoms, but many of these off episodes are underdiagnosed, and they're not really treated optimally. So it's really a lot of attention is needed to educate not only HCPs and, of course, some other stakeholders, but particularly patients."   "So the time also matters for stroke survivors. So it's very important that they start as soon as possible all the therapies, but also the physiotherapy at the same time. What this digital tool does is give two options. One is education on the one side, and on the other hand, a guided exercise that will enable people and stroke survivors to exercise at home. And with that, obviously, the personalized goals have been worked out together with the experts and HCPs so that they can achieve those goals faster, while working from home." #MerzTherapeutics #StrokeRehab #DigitalHealth #NeuroRehab #AccessToHealth #WorldStrokeOrganization #Physiotherapy #HealthEquity #TeleRehab #HCPs #Africafirst #AccesstoHealth #EquitableAccess #PostStrokeRehabilitation #PatientDrivenInnovation Merztherapeutics.com Download the transcript here

Click to Subscribe: https://bit.ly/Youtube-Subscribe-SoapDirt Young and the Restless spoilers show that Diane Jenkins (Susan Walters) plots a daring escape to free herself from the clutches of Patty's (Andrea Evans) sinister doctor. Meanwhile, Nikki Newman (Melody Thomas Scott) faces a daunting diagnosis that leaves her terrified. Victor Newman (Eric Braeden) is blindsided by a secret revelation, while Jack Abbott (Peter Bergman), in his growing desperation to find his wife, takes some risky decisions.  Y&R spoilers reveal that Victor proposes that Claire Grace Newman (Hayley Erin) spearhead a new publishing division. Concurrently, Victoria Newman (Amelia Heinle) accompanies her mother, Nikki, to the doctor where they receive a distressing diagnosis - a mass on her optic nerve could lead to blindness if left untreated. Despite the risks associated with surgery and her Multiple Sclerosis, Nikki is advised to act promptly.  The Young and the Restless spoilers indicate that while Nikki grapples with her health crisis, Diane attempts to crack Patty's doctor's phone passcode. Frustrated by her confinement, she requests to join the doctor outdoors, only to be redirected to the gym downstairs. Diane's clever manipulation of the doctor hints at her impending escape. Y&R spoilers hint that Jack dealing with Patty's erratic behavior and threats to Diane's safety. In his desperation to locate Diane, Jack instructs his son, Kyle Abbott (Michael Mealor), to tail the doctor when he leaves.  More Young and the Restless weekly spoilers confirm that Nikki, fearful of losing her sight and not wanting Victor's pity, insists that Victoria keep her diagnosis a secret. However, her secret doesn't remain hidden for long as Victor uncovers something surprising about Nikki's diagnosis.  And, Y&R weekly spoilers show that the Abbott family makes a risky move to rescue Diane, while Stephanie Simmons (Vivica A. Fox) recruits Nate Hastings (Sean Dominic) for a special project.  This episode was hosted by Belynda Gates-Turner for the #1 Soap Opera Channel, Soap Dirt. Visit our Young and the Restless section of Soap Dirt: https://soapdirt.com/category/young-and-the-restless/ Listen to our Podcasts: https://soapdirt.podbean.com/ And Check out our always up-to-date Young and the Restless Spoilers page at: https://soapdirt.com/young-and-the-restless-spoilers/ Check Out our Social Media... Twitter: https://twitter.com/SoapDirtTV Facebook: https://www.facebook.com/SoapDirt Pinterest: https://www.pinterest.com/soapdirt/ TikTok: https://www.tiktok.com/@soapdirt Instagram: https://www.instagram.com/soapdirt/

Vitamin D and multiple sclerosis have been linked for decades, but how strong is the evidence – and what does it mean for clinical practice? In this episode of the ECTRIMS Podcast, host Brett Drummond speaks with Prof. Eric Thouvenot from University Hospital of Nimes and Dr. Deborah Mason from Christchurch Hospital about the evolving science behind vitamin D and MS. Together, they explore: Why vitamin D deficiency is associated with increased MS risk The influence of latitude, sunlight exposure and genetics How vitamin D affects immune regulation and inflammation Findings from recent vitamin D supplementation trials As researchers continue to investigate vitamin D's role in MS, this episode provides a balanced look at what we know, what remains uncertain, and what it means for patient care.

"We aren't looking for answers yet. We're learning how to sit with the questions." As we prepare for an upcoming appointment with our neurologist, a simple question from Jennifer sparked a conversation neither of us expected to have. What if Dan's MS has progressed? To be clear, nothing has changed. We haven't received any new diagnosis, and Dan has not been reclassified from relapsing-remitting MS to secondary progressive MS. But after nearly three decades of living with Multiple Sclerosis and noticeable changes in his gait and energy levels, it felt like an important conversation to have. In this episode, we talk openly about our fears, questions, and uncertainties that can come with long-term MS. We discuss: What prompted us to start talking about disease progression before our upcoming neurology appointment How physical therapy has revealed both strengths and challenges in Dan's mobility and endurance Jennifer's experience transitioning from relapsing-remitting MS to secondary progressive MS years ago The realities of caregiving, aging, and adapting to changes in ability over time Why community, conversation, and preparation matter when facing difficult questions about the future More than anything, this episode is about facing possibilities without letting them define us. Regardless of what happens at our next neurology appointment, we are still the same people we were before we walked into the office. We hope you'll join us for this conversation, especially if you've ever wondered what the future might hold for your MS or how to navigate the uncertainty that comes with living with a chronic illness. *** Remember to rate, review, and subscribe to A Couple Takes on MS Podcast for two insightful perspectives on this one multifaceted disease.

In this deeply healing episode of Mirror Talk: Soulful Conversations, Christine Ruch joins us to explore nervous system healing, body wisdom, chronic illness, emotional capacity, and the sacred journey of healing from within.Christine is a Holistic Transformation Guide who helps people reconnect with their body's innate intelligence and healing potential. After walking through her own 20-year healing journey with Multiple Sclerosis and chronic health challenges, she now supports others in restoring their nervous system, rebuilding self-trust, releasing stored trauma, and returning to deeper alignment in body, mind, soul, and spirit.This conversation is an invitation to stop fighting the body and begin listening to it. Christine reminds us that symptoms are not always enemies to silence. Sometimes, they are messengers guiding us toward truth, surrender, compassion, and inner restoration.In This Episode, We ExploreNervous system healing as a gateway to transformationHow chronic illness can become an invitation to listen more deeplyBuilding emotional capacity and resilienceWhy many people feel disconnected from their bodiesThe role of trauma, unresolved emotions, and stored pain in healingHow to release control and trust the body's intelligenceWhat aligned embodiment looks like in everyday lifeThe meaning of holding space without fixing or forcingHow personal healing contributes to collective healingA loving first step for anyone feeling tired, stuck, or discouragedKey TakeawaysYour body is not your enemy. It may be carrying messages that need compassion, attention, and deeper listening.Nervous system restoration can help create the inner safety needed for emotional release, trauma healing, and spiritual alignment.Healing is not only about symptom management. It is also about rebuilding trust with yourself and learning how to live from a calmer, more connected place.Emotions are not who you are. They can be witnessed, felt, and released without becoming your identity.The illusion of control can keep us disconnected from the deeper intelligence of the body. Surrender can open the door to liberation.Memorable Quotes“I love life.”“Your emotions are not who you are.”“She'd be really proud of me.”Chapters00:00 The Journey of Healing and Transformation07:44 Listening to the Body's Wisdom17:29 Trust, Surrender, and Self-Love22:01 The Illusion of Control25:10 Building Emotional Capacity27:53 Witnessing Emotions Without Judgment32:42 The Journey to a Calmer Nervous System36:29 Healing from Within38:03 Holding Space for Others42:51 Embarking on the Healing JourneyConnect with Christine RuchWebsite: https://www.christineruch.com/Substack: The Fresh LifeListen to This Episode If You Are AskingHow do I begin healing from within?Why does my body feel overwhelmed or unsafe?How can I rebuild trust with my body after illness?What does nervous system healing really mean?How can emotional capacity support trauma release and inner peace?Gentle NoteThis episode is shared for educational and inspirational purposes only. It is not medical advice. Please consult a qualified healthcare professional for medical diagnosis, treatment, or personal health decisions.If this conversation encouraged you, please share it with someone who is walking through a healing journey. Subscribe to Mirror Talk: Soulful Conversations, leave a review, and continue the journey with us as we explore healing, purpose, self-awareness, and transformation.Watch on YouTube: https://youtu.be/917B8Ex-SOc Try Aletheia today: https://aletheia.mirrortalkpodcast.com Ask what is on your heart. Mirror Talk will reflect back what may help you see more clearly. Try it here: https://mirrortalkpodcast.com/ask-mirror-talk/Could you support us by becoming a Patreon? Please consider subscribing to one or more of our offerings at http://patreon.com/MirrorTalk 

This week, our coverage of the Consortium of MS Centers annual meeting continues with my guest, Dr. Stephen Krieger. In a wide-ranging conversation, Dr. Krieger offers a very encouraging clinical trial update, shares his thoughts on what treating someone living with advanced MS ought to look like, and points out potential obstacles to implementing the updated criteria for diagnosing MS.  Dr. Krieger is a Professor of Neurology at the Icahn School of Medicine at Mount Sinai in New York, and a Multiple Sclerosis Specialist at the Corinne Coldsmith Dickinson Center for MS. We're also sharing results of a study that revealed some surprising connections between caffeine, alcohol, opioids, and MS symptoms. And if you're living with MS and you're the parent of a young child, we'll tell you about a book that belongs on your bookshelf. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: We're at the CMSC annual meeting with Dr. Stephen Krieger  :22 Study reveals the connection between caffeine, alcohol, and opioids and your MS symptoms    1:12 My Superhero with Wheels is the book you need if you're living with MS and have young children  5:15 Dr. Stephen Krieger discusses exciting clinical trial results, treating people with advanced MS, and potential challenges in implementing the updated criteria for diagnosing MS   8:39 Share this episode  30:22 Next week  30:41 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/458 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes at www.RealTalkMS.com STUDY: Daily Temporal Associations Between Psychoactive Substances and Fatigue, Pain, Stress, and Depressive Symptoms in People with Multiple Sclerosis https://archives-pmr.org/article/S0003-9993(26)00035-3/fulltext BOOK: My Superhero with Wheels https://amazon.com/My-Superhero-wheels-True-Story/dp/B0GWVGSWX5/ref=sr_1_1 JOIN: The RealTalk MS Facebook Group https://facebook.com/groups/realtalkms REVIEW: Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on X, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 458 Guest: Dr. Stephen Krieger Privacy Policy

In this episode of Brain Chat, I'm joined by MS advocate Nana Opong-Owusu and exercise physiologist Sheree Love for an honest and empowering conversation about movement and brain health.We talk about what it really looks like to stay active while living with Multiple Sclerosis—, rom navigating fatigue and fear of symptom flares to letting go of unrealistic expectations around exercise. This conversation is all about reframing movement as something that is accessible, adaptable, and supportive, not overwhelming.Together, we explore how intentional movement can positively impact cognition, mood, and overall nervous system health, and share practical ways to get started at your own pace.Whether you're newly diagnosed or further along in your journey, this episode offers real-life insight, encouragement, and tools to help you move in a way that works for you.

Montel Williams grew up in one of Baltimore's toughest neighborhoods. At 7 years old, a teacher tried to define him by the color of his skin. That day, he made a decision that shaped everything  no one else would ever own the definition of who he was.That mindset took him from the streets of Baltimore to the Naval Academy, from military intelligence to 17 years of daytime television with 100% creative control and through a diagnosis of Multiple Sclerosis he's been fighting for over 20 years.In this conversation, Moshe Popack sits down with Montel Williams to talk about discipline, faith, and what it really means to build a life on your own terms.Timestamp: 0:00 Growing Up in One of Baltimore's Toughest Neighborhoods3:30 The Belief He's Carried Since Childhood5:00 First African American to Graduate the Naval Academy Prep School7:00 How a Speaking Tour of 1.5M Kids Built a TV Empire9:00 100% Creative Control  Why the Show Lasted 17 Years10:00 The Real Reason Most People Never Know Who They Are11:30 What Fatherhood Actually Teaches You About Letting Go13:30 The MS Diagnosis and the Fight That Followed15:00 How to Reduce Inflammation and Take Control of Chronic Illness16:00 The Only Way Out Is Through  His New Project25:30 The Teacher Who Tried to Define Him in Second Grade27:00 What Montel Williams Wishes for the World

“For a long time, I assumed caregiving was simply what spouses do. Then hernia surgery showed me just how much family caregivers carry every day.” We have participated in Older Michiganians Day at the Michigan State Capitol for more than two decades, advocating for programs and policies that help people age and live independently in their own homes. What began as advocacy for Jennifer and the MI Choice Medicaid Waiver Program has evolved into something much broader: advocating for caregivers, aging in place, and the support systems that help people live with dignity in their own homes. In this episode, we reflect on a surprising realization that the young couple who first attended Older Michiganians Day more than 20 years ago (that's us!) now officially qualify as "older Michiganians" themselves. We discuss Dan's opportunity to speak on the Capitol lawn about family caregiving, the lessons learned during his recent hernia surgery recovery, and why support for unpaid family caregivers is becoming increasingly important as Michigan's population ages. In this episode, we get real about: Realizing we have become the "older Michiganians" we once joked about not being How the MI Choice Medicaid Waiver Program helps Jennifer remain at home The often-invisible work performed by unpaid family caregivers Proposed Michigan legislation supporting family caregivers Aging with Multiple Sclerosis while continuing to advocate for change We hope this conversation encourages you to learn more about caregiving, advocacy, and the importance of supporting those who support others. Here are the links that offer further insights into our conversation: This conversation serves as a companion to our recent Older Michiganians Day essay, where we share photos from the event, Dan's speech, and additional information about the caregiving advocacy efforts discussed in this episode. Learn more about the Michigan MI Choice Medicaid Waiver Program Explore Older Michiganians Day 2026 resources supporting family caregivers and aging in place Thank you for listening to A Couple Takes on MS. We are honored to be included among FeedSpot's 40 Best Multiple Sclerosis Podcasts. While rankings aren't why we do this work, we're grateful for the opportunity to share our experiences and connect with others navigating life with MS. *** Remember to rate, review, and subscribe to A Couple Takes on MS Podcast for two insightful perspectives on this one multifaceted disease.

Kim Curry was a radio broadcaster for 33 years in some of America's finest cities: Pueblo,Knoxville, San Antonio, Washington, D.C., Baltimore, and Miami. Curry was a DJ in differenttime slots and obtained the position of Program Director at two of America's legendary stations:KTSA-AM San Antonio and Power 96, Miami.The diagnosis of Multiple Sclerosis forced Curry to retire from broadcasting in 2005 resulting inrelocation, the search for doctors, therapists, and emotional family strain.. Eight years of rapidphysical decline was halted by the magic of modern medicine, chronicled in his memoir, “ComeGet Me Mother, I'm Through.”Curry has continued his writing journey, with two other published books. “The Death of Fairness”and “Bonnie's Law, The Return to Fairness" which was an “Amazon Number One Best Seller.”Tell Me What Happened features the music of Susan Salidor.More information about Susan Salidor can be found at her website Get Susan Salidor's One Little Act of Kindness Children's BookGet Susan Salidor's I've Got Peace in My Fingers Children's BookMore Information about our sponsor's 10 x 10 Blackhole Chess game can be found at www.blackholechess.com

Welcome to Episode 303 of the Spun Today Podcast—your home for honest conversations about writing, creativity, and the journeys that shape us. I'm your host, Tony Ortiz, and today we're releasing a truly special episode to honor World MS Day. In this heartfelt conversation, I sit down with my wife, Zoila Ortiz, to share her powerful story of living with multiple sclerosis. We dive deep into her first symptoms, the uncertainty of diagnosis, and the emotional and physical challenges that come with MS. Zoila walks us through her search for information, the importance—and dangers—of online self-diagnosis, and the strength found in community. Through candid discussion, Zoila offers an inside look at adapting to adversity, the rollercoaster of medications (Glatiramer by injection (Copaxone) and Fingolimod (Gilenya) to the current day infusion Rituximab which is a monoclonal antibody). We touched on clinical trials, and the vital role of support systems. She talks openly about how MS can impact confidence, independence, and daily routines—but also about how determination and a strong mindset can turn even the most daunting obstacles into new paths forward. We dig into the importance of raising awareness, supporting one another, and using our platforms to connect and inspire. Tune in for a conversation about resilience, empathy, and the healing power of storytelling—and learn how you, too, can advocate for others and yourself.   The Spun Today Podcast is a Podcast that is anchored in Writing, but unlimited in scope.  Give it a whirl.      Twitter: https://twitter.com/spuntoday  Instagram: https://www.instagram.com/spuntoday/  YouTube: https://www.youtube.com/@spuntoday   Website: http://www.spuntoday.com/home  Newsletter: http://www.spuntoday.com/subscribe    Links referenced in this episode:      Follow Zoila: @melodyrosa2083   What is Multiple Sclerosis video from ASAP Science: https://www.youtube.com/watch?v=Naecv3h868c   To donate for MS research or partake in activities like Bike MS, Walk MS, or just to learn more, check out the National MS Society: http://www.nationalmssociety.org/     Jpmetz YouTube Page: https://www.youtube.com/@jpmetz     Get your Podcast Started Today! https://signup.libsyn.com/?promo_code=SPUN (Use Promo code SPUN and get up to 2-months of free service!)   Check out all the Spun Today Merch, and other ways to help support this show! https://www.spuntoday.com/support     Check out my Books Make Way for You – Tips for getting out of your own way ÁBRЕТЕ CAMINO: CONSEJOS PARA DEJAR DE SER TU PROPIO OBSTÁCULO (Spanish Edition) FRACTAL – A Time Travel Tale Melted Cold – A Collection of Short Stories   http://www.spuntoday.com/books/ (e-Book, Paperback and Hardcover are now available)   Fill out my Spun Today Questionnaire if you're passionate about your craft.  I'll share your insight and motivation on the Podcast: http://www.spuntoday.com/questionnaire/     Shop on Amazon using this link, to support the Podcast: https://amzn.to/4km592l      Shop on iTunes using this link, to support the Podcast: https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewTop?genreId=38&id=27820&popId=42&uo=10   Shop at the Spun Today store for Mugs, Notebooks, T-Shirts and more: https://spuntoday-shop.fourthwall.com/   Music: https://www.purple-planet.com   Outro Background Music: https://www.bensound.com   Spun Today Logo by: https://www.naveendhanalak.com/   Sound effects are credited to: http://www.freesfx.co.uk   Listen on: ApplePodcasts | Spotify | Pocket Casts | YouTube | Website

What if the future of multiple sclerosis treatment could go beyond suppressing inflammation - and actually help protect the brain? In this episode of Rx for Biotech, host Chris Leidli sits down with Jason Tardio, President & COO of Immunic Therapeutics, to discuss the evolving future of treatment for Multiple Sclerosis (MS), one of the most complex autoimmune and neurodegenerative diseases affecting millions worldwide. Jason shares his deep experience leading major MS franchises at Biogen and Novartis, explains how MS attacks the brain and spinal cord, and breaks down why many current therapies focus primarily on inflammation but may not fully address the neurodegeneration driving long-term disability. The conversation also explores Immunic's lead investigational therapy, vidofludimus calcium, an oral once-daily treatment being studied in Phase 3 clinical trials for relapsing multiple sclerosis. The company believes the therapy may offer a unique dual approach by targeting both neuroinflammation and neurodegeneration. Topics discussed include: • What causes multiple sclerosis • Early symptoms and diagnosis of MS • How MRI imaging transformed MS care • Why MS remains difficult to treat • The difference between inflammation and neurodegeneration • Oral therapies vs infusions and injectables • Progressive multiple sclerosis and unmet patient needs • The future of neuroscience, immunotherapy, and personalized medicine For patients, caregivers, healthcare providers, and anyone interested in the future of neurology and autoimmune disease treatment, this episode offers an accessible and hopeful look at where MS care may be headed next.

A cure for neurodegenerative diseases might be frolicking through the mountains. New research from…

What happens when a high-achieving, in-charge leader faces a challenge that can't be solved by sheer determination? In this episode, we sit down with Melissa Borowicz — CEO and owner of The Utech Group, organizational development expert, and co-author of Cracking the Rich Code — to explore what it looks like to face uncertainty through the lens of an ENFJ personality type. Melissa shares how her Big Five profile (94th percentile in adventurousness, 6th percentile in stress quotient) shaped her instinct to "always find a way" — and how an unexpected Multiple Sclerosis diagnosis in 2023 forced her to reckon with the shadow side of that same strength. We explore her development as a leader inside a second-generation family business, the tension between her natural independence and the need to receive support, and what she's learned about setting boundaries when your identity is built around achievement. In this episode you'll hear about: - What ENFJs look like under pressure — and what "laser beam eyes" and task-mode mean in practice - The difference between Interaction Styles (In Charge) and Essential Motivators (Catalyst) and how they showed up in Melissa's leadership journey - How her MS diagnosis accelerated both personal growth and organizational change - The framework she used to navigate life's most uncertain chapter — and why she wrote a chapter about it - Why "just do something" might be the most powerful advice for anyone stuck in uncertainty Whether you're a personality nerd, a leader navigating change, or someone facing something you didn't ask for, this episode will leave you thinking differently about how you're wired — and what your wiring reveals when life gets hard. Connecting the Dots is hosted by Steve Utech (Founder, illumyx) and Ryan Gracyalny (Director of Training & Development, The Utech Group). About Melissa Borowicz Melissa Borowicz is the CEO and Owner of The Utech Group, a second-generation family business specializing in organizational development, change management, and leadership training based in Green Bay, Wisconsin. With a master's degree in marriage and family therapy, Melissa brings a uniquely human lens to the complex dynamics of business — especially in family-owned companies navigating transition. Melissa is a co-author of Cracking the Rich Code, where she shares her personal chapter on mastering uncertainty and finding strength during her own Multiple Sclerosis diagnosis.

Balancing disease control with pregnancy and neonatal considerations in people with neuroinflammatory disease throughout the family planning, pregnancy, and postpartum periods is crucial. Modern treatment paradigms enable women to safely become pregnant and breastfeed alongside effective disease management. Shared decision making is an important part of this process. In this episode, Kait Nevel, MD, speaks with Ruth Dobson, MD and Kerstin Hellwig, MD, authors of the article "Family Planning in Neuroinflammatory Disease" in the Continuum® April 2026 Multiple Sclerosis and Related Disorders issue. Dr. Nevel is a Continuum® Audio interviewer and a neurologist and neuro-oncologist at Indiana University School of Medicine in Indianapolis, Indiana. Dr. Dobson is a professor in the Centre for Preventive Neurology at the Wolfson Institute of Population Health, Queen Mary University of London, and a consultant neurologist in the Department of Neurology at the Royal London Hospital, Barts Health NHS Trust, in London, United Kingdom. Dr. Hellwig is a professor in the Department of Neurology at Katholisches Klinikum, Ruhr‑Universität Bochum, in Bochum, Germany. Additional Resources Read the article: Family Planning in Neuroinflammatory Disease Subscribe to Continuum®: shop.lww.com/Continuum Earn CME (available only to AAN members): continpub.com/AudioCME Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the American Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Host: @IUneurodocmom Guest: @drruthdobson Full episode transcript available here

Clement Manyathela speaks to Clinton Rambanapasi, the Roche Medical Partner for Neuroscience, about what causes multiple sclerosis ahead of World MS Day. You’re listening to The Clement Manyathela Show on 702. Clement Manyathela makes sense of the news of the day while sharing information to guide you through daily life. As your morning friend, he tackles both the serious and the light-hearted on your behalf. Thank you for listening. Listen live on Primedia+ weekdays from 9 am to 12 pm (South African time) on 702 https://buff.ly/gk3y0Kj For more from the show and catch-up podcasts, visit Primedia+ https://buff.ly/XijPLtJ Subscribe to the 702 Daily and Weekly Newsletters https://buff.ly/v5mfetc Keep the conversation going online: 702 on Facebook https://www.facebook.com/TalkRadio702 702 on TikTok https://www.tiktok.com/@talkradio702 702 on Instagram: https://www.instagram.com/talkradio702/ 702 on X: https://x.com/Radio702 702 on YouTube: https://www.youtube.com/@radio702 See omnystudio.com/listener for privacy information.

Got feedback about this episode? Send Carolyn a textI'm joined by Winnipeg runner Darolyn Walker for a powerful and perspective-shifting conversation about running, resilience, and redefining what success looks like.Darolyn's story spans more than two decades — from competing at a high level in her university and national track days, to navigating a multiple sclerosis diagnosis in her mid-20s, to raising three children while continuing to train, race, and adapt through unpredictable health challenges.We focus in particular on her remarkable performance at the Boston Marathon, where she ran 3:05:37 while living with MS — a result that sits at the intersection of high level performance and deep gratitude for simply being able to run.But this conversation isn't really about times or records. It's about identity, acceptance, letting go of old definitions of success, and finding meaning in movement through changing seasons of life.SPONSOR: Cure Hydration. Staying hydrated isn't just about water — you also need electrolytes. Real ingredients. Real hydration.Visit curehydration.com/INSPIREDSOLES for 20% off. Connect with Darolyn:Instagram: @darolynwalkerFacebook: @darolyn.walker.7Connect with Carolyn:Instagram: @inspiredsolescast or @carolyn.c.coffinYou can help spread the running love! The best way to SUPPORT Inspired Soles is to share your favourite episode(s) with friends, subscribe, or leave a rating and review on Apple Podcasts. Connect on Instagram @inspiredsolescast or email guest ideas to inspiredsolescast@gmail.com. 

May 30th is World MS Day! This year, the theme for World MS Day is "My MS Diagnosis," and I've been thinking about what happens right after that diagnosis. After an individual hears, "You have MS." This week, Dr. Nancy Sicotte joins me to discuss the things you should know, the things you should be thinking about, and the things you should be doing in the first 100 days following an MS diagnosis.  Dr. Sicotte is the Chair of Neurology and Director of Multiple Sclerosis and Neuroimmunology at Cedars-Sinai in Los Angeles, and she's the past Chair of the National MS Society's National Medical Advisory Committee.  We're also sharing results of a study that showed an exercise hormone protected neurons from inflammatory attack in a mouse model of MS. And we're sharing encouraging news about an experimental nasal spray that's been shown to delay disability progression and improve fatigue among people with non-active secondary progressive MS. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: World MS Day!  :22 Study reveals an exercise hormone has neuroprotective effects on a mouse model of MS    2:40 Tiziana shares evidence that Foralumab delays progression and improves fatigue in people with non-active secondary progressive MS  4:34 Dr. Nancy Sicotte looks at the first 100 days following an MS diagnosis  8:40 Share this episode  28:51 Next week  29:12 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/456 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes at www.RealTalkMS.com World MS Day Poster Maker https://worldmsday.org/poster-maker STUDY: The Exercise Hormone Irisin Has Neuroprotective Effects in a Mouse Model of Multiple Sclerosis https://www.nature.com/articles/s42255-026-01527-7 CLINICAL TRIAL: A Study of Nasal Foralumab in Non-Active Secondary Progressive Multiple Sclerosis Patients https://clinicaltrials.gov/study/NCT06292923 JOIN: The RealTalk MS Facebook Group https://facebook.com/groups/realtalkms REVIEW: Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on X, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 456 Guest: Dr. Nancy Sicotte Privacy Policy

Palliative care in multiple sclerosis spans the disease course, from early screening and support after diagnosis to symptom management and quality‑of‑life optimization in midstage disease, and end‑of‑life care in advanced MS. This episode outlines a staged approach to palliative care, highlights the roles of neurology and primary care teams, and discusses tools such as patient‑reported outcomes and symptom scales to support ongoing assessment of patients and care partners. In this episode, Katie Grouse, MD, FAAN, speaks with Penelope Smyth, MD, FRCPC and Janis M. Miyasaki, MD, MEd, FRCPC, coauthors of the article "Palliative Care in Multiple Sclerosis" in the Continuum® April 2026 Multiple Sclerosis and Related Disorders issue. Dr. Grouse is a Continuum® Audio interviewer and a clinical assistant professor at the University of California, San Francisco in San Francisco, California. Dr. Smyth is the director of the Division of Neurology in the Department of Medicine at the University of Alberta in Edmonton, Alberta, Canada. Dr. Miyasaki is a professor in the Division of Neurology in the Department of Medicine at the University of Alberta and the zone clinical department head for Clinical Neurosciences at Alberta Health Services in Edmonton, Alberta, Canada. Additional Resources Read the article: Palliative Care in Multiple Sclerosis Subscribe to Continuum®: shop.lww.com/Continuum Earn CME (available only to AAN members): continpub.com/AudioCME Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the American Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Full episode transcript available here Dr Grouse: With the new treatments for MS, people might be saying palliative care is not relevant at all. It's about giving up hope and hopelessness. But this article covers why palliative care is important for your patients and families throughout their illness trajectory. Dr Jones: This is Dr Lyell Jones, Editor-in-Chief of Continuum. Thank you for listening to Continuum Audio. Be sure to visit the links in the episode notes for information about earning CME, subscribing to the journal, and exclusive access to interviews not featured on the podcast.  Dr Grouse: This is Dr. Katie Grouse. Today, I'm interviewing Drs Penelope Smyth and Janis Miyasaki about their article on palliative care in multiple sclerosis, which appears in the April 2026 Continuum issue on multiple sclerosis. Welcome to the podcast, and please introduce yourselves to our audience.  Dr Smyth: Thank you, Katie. I'm Penny Smyth. I am a neurologist at the University of Alberta, a professor in neurology, and a clinical multiple sclerosis specialist.  Dr Miyasaki: Hi, Katie. Thanks for having us. I'm Janis Miyasaki. I am a movement disorder neurologist primarily who also provides neuropalliative care at the University of Alberta in Edmonton, Canada.  Dr Grouse: It's so great having you today to talk with us about your article. I thought this article was really a wonderful take on the topic. I learned a lot, and I'm really hoping all of our listeners will take advantage of this article and take advantage of all the learning they can get from reading about this topic. So, I wanted to start with a more general question, which is, what is the key message from this article that you're hoping your readers will take away?  Dr Smyth: In terms of key takeaways, I think it's our hope that neurologists will come away from reading this article with, really, an expanded understanding of what palliative care is and how that might be applicable to them in their care for their patients with MS along a continuum of treating people with MS, that there can be components of palliative care and strategies that can be integrated early after diagnosis in, really, anywhere along the continuum of caring for people with MS. We've called that kind of mid-stage. And then there are particular needs for people with MS and their care partners in late-stage or severe MS and end of life that might require different palliative care strategies. I think we kind of have maybe a bit of a bias sometimes in thinking of palliative care as more directed towards those that are near end-of-life. But in fact, it's a much expanded concept.  Dr Miyasaki: And I'll just add that we also discuss a palliative approach, that palliative care skills and philosophies can be used by generalists---in this case, neurologists who are providing care to people with MS---and that adopting certain skills and communication techniques can help us better address our patients' and their families' symptoms. And also to keep in mind that for most people with neurologic illness, the unit of care is not only the patient, but it's the patient and the family, however that family looks.  Dr Grouse: Now, Penny, I'm curious, how are early-stage and mid-stage multiple sclerosis palliative care strategies different from, say, a typical evaluation and counseling that a neurologist would give, say, an MS specialist or even a general neurologist?  Dr Smyth: Thank you, Katie. That's a great question, and something that actually I learned in writing this piece with Janice and from her as a neuropalliative care expert. I think in terms of early strategies around palliative care that can be helpful to the general neurologist in their office, palliative care is about holistic support for patients and their care providers spiritually, emotionally, physically. There are components of palliative care and symptom management and making sure that the patient is at the center of the care, as well as support for their care partners with their holistic approach of relief of suffering as well as offering hope. When I started this piece, I was thinking that many of us neurologists, I think, often informally utilize many of these components already when we're dealing with patients early on after diagnosis in terms of communication, counseling, and education; going through their fear of an uncertain future; spiritual well-being; and then connecting them with supports for adaptive coping strategies. And then as well in mid-stage, which is really around what we can do in symptom management and improving quality of life, with screening tools and patient-reported outcome measures. However, I have to say that there are many unmet needs for people with MS and their care partners that they identify that are clearly not being met by us neurologists in this day and age. So even though we may be incorporating some of these strategies, I don't think we're meeting the mark all the time and hitting the target, especially in our busy office practices, in various ways. Dr Grouse: Given that, at a high level, what are some important early-stage MS palliative care concepts that we should be keeping in mind when we are counseling patients in these stages of the disease? Dr Miyasaki: An important concept to keep in mind for neurologists dealing with early-stage MS patients is that for us, we feel successful that we have made a diagnosis. And yet for the patient, it is taking away that hope. Maybe it's not MS. Maybe I just have a numb hand and it's gonna go away. And for us to appreciate that while we make this diagnosis multiple times a week---or, for MS specialists multiple times a day---for this person, it is the first time, the first experience, and it shakes their entire foundation of who they are as a person, how they will perform all the tasks and roles that they have in society, in their professional lives, in their family structures, and in their close, intimate relationships. As physicians, we may be overwhelmed by acknowledging that. I feel that it's important for us to understand the needs that our patients have and to allow them to have their feelings. You know, feelings can feel messy and time-consuming, and yet when we fully see our patients, I feel that this is the best of medicine. And it certainly is, in terms of palliative care, the principle that we seek. We accept all of the patient, the joy and the sorrow, the anger and the frustration. We accept it all, and we try to determine what will serve this person who is suffering in front of us now.  Dr Smyth: There's another piece to this, which came up as Janice and I were writing together. We were talking about offering a prognosis to a patient as to how they would do, and this was something that I thought deeply about, because I said, we always communicate how uncertain the prognosis is and how we can't predict the future. And then she said to me, well, what about offering a roadmap to a person with MS soon after diagnosis as to how you're gonna determine how they do over the next couple of years? Which are really important years in terms of determining how patients are doing on their disease-modifying therapies, whether they're having progression or not, and things. It's a pivotal time. So, if you can offer a roadmap to a person with MS and say, look, this is when we will be following you up. This is how we will be following you with MRI and biomarkers if you have that available, and this is how we will determine how responsive you are and then how we move forward from there. Dr Grouse: Really important concepts. And the roadmap certainly makes a lot of sense to me and something that, apart from just being useful to the patient for so many reasons to help set expectations, you know, is useful for us to better partner with the patient so they understand this is sort of how we do things and everyone's sort of expectations are met. So, I think those sound like really great goals and things to keep in mind. Now, we talked about early-stage MS palliative care concepts. How does that change as you get into the mid-stage of the disease?  Dr Smyth: Yeah. So, this is reflecting the fact that the course of MS is so different and the experience of MS is so different person to person. And so, what do we do as neurologists when we follow these people long-term over years and decades of living with their MS as their needs evolve, as their symptoms evolve, and as their disability evolves? Well, really, this is about the time of getting into, what are the symptoms that they're struggling with, what are the causes of their suffering at various points? And then how do we identify that, maybe with use of patient-reported outcome measures, screening scales, things like that. And then how do we direct symptomatic management to the specific symptoms that are causing distress to the patient? As well as trying to improve their quality of life in various ways, treating their comorbidities, making sure to check on exercise, healthy living, and that kind of thing.  Dr Grouse: Now getting into, I think, topics that we're more used to thinking about when we think about palliative care: a lot of us, I think, are really unsure of the right time to discuss advanced care directives in the course of multiple sclerosis, and I think that's not helped by the fact that many of us are just, in general, not terribly comfortable talking about those types of things in general. What is your advice to questions like this?  Dr Smyth: And this is something that, again, Janice and I had to come together on, because there is no universal accepted time for when is the right time in multiple sclerosis to discuss advanced care directives and goals of care. And in fact, when they have looked at it in the literature, different things have come out. It has come out that neurologists can be uncomfortable discussing this. There's unique challenges to people with MS in that they have a diagnosis at a young age with an uncertain trajectory of how their course of disease is going to go. And many of these things lead care providers to be somewhat hesitant as to when is the right time, as well as, there were identified barriers within patients themselves as to when the right time might be to discuss. In that, you know, some of the coping strategies might be, as identified by some of the qualitative studies that have been done on this, around the fact that they would prefer to focus on the present rather than the future. In some studies expressed an ambivalence as to when they thought the right time might be, as well as some negative experiences that they might have had from providers trying to discuss these things in their previous experience. So, I went back to looking at the European guidelines for palliative care in MS, who suggested when a person might have severe MS---which they define as walking with bilateral aids for at least twenty meters or an EDSS of six or higher---or trigger-based, when there has been a change in the patient's status, when there's been a decline in some way or progression. Now, this is a little different, actually, than what we offer other people with neurologic diseases, and I don't know if that's the right answer. And this is where I'm going to turn it over to Janice, because I think we could learn something, as neurologists who treat people with MS, from our palliative care specialists.  Dr Miyasaki: I think of advanced care planning in a very different way. I think what a lot of the patients were expressing in the studies was that being asked about advanced care planning signaled to them in some way that they have reached this point in their illness where things aren't going so great and I anticipate that you may run into complications. Whereas in our movement disorder clinic, one of our fellows did a study looking at capacity for decision-making. And even in people who scored normally on the Montreal Cognitive Assessment, they had impairments in some of the domains of decision-making. And so, our philosophy in movement disorders at least---and some of our patients are quite young who have multiple system atrophy, they could be in their forties---we take the philosophy that everyone over the age of decision-making capacity, which is generally eighteen, should have some goals of care established. And how I introduce it in my clinic is, you know, for the young resident, you want the full-meal deal, because the likelihood of the resident surviving the ICU admission is very high. And then when we look at me, who… I am older, the likelihood of surviving an ICU admission is considerably lower. And so, the appropriate goals of care might be that I am willing to go to the ICU, and if things go well, then they can continue. But if things are not going well, they can have a discussion with my personal directive or power of attorney to talk about what the goals of care should be. And then the other aspect is sometimes having the conversation with family is really important because most of our families in hospital express an uncertainty. Am I doing the right thing? And they want to do the right thing for their loved ones. And most people actually say, if you ask them, I don't want to burden my family with making decisions that are going to tear at their hearts. So, then we can't actually make good informed decisions for our loved ones unless we have clear conversations. I think it does speak to our superstitious beliefs that if we talk about death, it's going to happen. But I hope the listeners will take my word for it, it really doesn't. And someone had a really good saying about the advanced directive. They're kind of like evening clothes. You should take them out every once in a while and make sure they still fit. And so, when you normalize it in this way, it helps people to just say, oh, yeah, it's once a year. Dr. Miyasaki is gonna ask me about how do I feel about those goals of care. And then it doesn't have this portent of, oh, I'm not doing well. Instead, it's just, this is what we should all be doing for our sake and for our family's sake.  Dr Smyth: Now, one thing that I have to add on to this is that it is important to try to establish advanced care directives before patients experience cognitive decline, because then that can make it a much more challenging conversation and brings nuances of challenge into the interactions, which, you know, are hard.  Dr Grouse: And Penny, I'm glad you brought that up, because I was really struck by that point too when reading this article, how easy it is to miss the subtle signs that cognitive changes are happening. I think it's just- it's a good kind of segue into that topic in general, but it is such an important link to, you know, making sure that you get those advanced directives at a time when the patient's really able to express and understand what they're talking to you about. Now, on the topic of the cognitive screenings, what's a good way to do this type of screening, and why is this type of screening so particularly important in the case of multiple sclerosis?  Dr Smyth: Yeah. Thank you, Katie. I think that it's important for our listeners to think about and recognize when we see our patients with MS because it is one of the invisible symptoms that people with MS can live with and may not be apparent on regular conversation in the office. So, it's important to deliberately ask about subjective challenges in cognition. Ask the partner about how they're doing in terms of their cognition in various ways. As well as asking them and exploring then, how are they doing in their professional roles if they're working or in their surroundings? How are they coping on a daily basis on a cognitive level in addition to a physical level? We know that cognitive issues are actually the biggest contributor for not working and are a huge driver of disability in MS in terms of functioning, even more than physical decline in many ways. So, it is important for us neurologists to keep top of mind and to think about and deliberately attend to. There are screening tests that we can do in the office. The easiest for us, which measures the verbal processing speed, is the SDMT test, which is a ninety-second test matching symbols and numbers. It's easy to do. You can train a MOA to do it before you see the patient and things like that, and it just gives you an idea as to where the patient is at. And usually they're having difficulties if they're greater than two standard deviations below the norm for their age, or if there's a significant drop of four or eight points, and that might signal to you that there might be more going on. You can explore it, and then if you do have this available, the ability to refer for neuropsychological testing if there's questions. But often we can't get it with the MoCA score, unfortunately.  Dr Grouse: Talking about all these concepts, I think they all sound great. I think a lot of us hearing this will naturally say, "Yes, these are absolutely things we should be incorporating in the care of these patients." What I wondered about was, certainly we're all very busy, it is really hard to find time for a lot of these things. We don't always have access to specialists who can help us with some of these conversations. How can we find time, and how can we work this into the care of our patients effectively and still make time for all the other things we have to talk about, and make sure that we're seeing all of our other patients and staying on time and all of those things?  Dr Miyasaki: Yes. I think that's the challenges of dealing with people who actually, over time, their care needs increase, is huge in neurology. I can't think of a single subspecialty where care actually gets easier. It's constantly getting harder. You know, having come from private practice, I completely understand my colleagues' challenges in the community. Some of the ways that other groups have managed this when they don't have government or university support in their center is actually to look at not-for-profits. There are a lot of not-for-profits that can help in terms of wayfinding for social services, explaining to the patients and the family what is available to them. And in fact, some of them can also provide some cognitive supports, as well as point them in the way of day programs. And many of them have very established caregiver support groups, as well as patient support groups for various stages of their illness. So, I think it requires for the individual or small or even a large group practice to be inventive, to look in your community and see what resources are available and free for your patients in order to establish that loose team without boundaries to help your patients. Of course, for those in academic centers, I know that times are tight for all of us, and if you haven't established a team, it is a challenge; and then learning how to write a business plan or a briefing note for your institution and to learn how to speak the love language of administrators, is really key to putting forward the needs of our patients. Which, compared to heart attack patients or hips and knees, they are very rare, and yet our patients can result in significant cost to the healthcare system. So, we do have an opportunity to make the case that putting a little bit of investment in the ambulatory setting can result in significant cost savings to the system when it comes to acute care hospitalization.  Dr Smyth: So, I was thinking, Janis, as you were talking about that, when you were talking about not-for-profit groups, it's really the MS societies in various countries that are very active in this and have a lot of resources available, especially for care partners.  Dr Grouse: Those are really great tips. Thank you for bringing those up as potential other resources we can take advantage of. I wanted to ask specifically about physician-assisted death and assisted suicide, which certainly does come up, especially in later-stage parts of the disease. How can palliative care specialists be helpful when patients do express interest in these types of interventions?  Dr Miyasaki: As you know, Katie, in Canada, we've had a legislative right to access to what we call medical assistance in dying. When the legislation passed, one of my other colleagues and I felt that these were the only conversations we were having with our patients. In all this experience, I have sort of developed in my mind a framework of people who are what we call MAID-curious. They want to know what their rights are and how it would look, when they feel the time is close, for them to exercise that right. And then there are those who are fearful of future suffering. And some of them may have a very unrealistic view of what the future will look like. And this may be in particular for multiple sclerosis because many of the public's view is based on what treatment was like thirty years ago. It may not be informed by more recent treatment where patients actually do quite well, and the majority never get to progressive MS. And so, to explore and be open to that request is the first thing that is important. And then if the person has unresolved symptoms that, traditionally, we can't care for, the palliative care specialist can be very helpful because they just have inventive ways of looking at things. They look at it outside the box, and they have a different toolkit available to them. I would not want all neurologists to just send all these patients requesting physician-assisted death to their palliative care colleagues. But I think for those who are having unaddressed symptoms, it can be very helpful. Certainly, if there is an acute event in the hospital, then this is a time of crisis. And often hospitals will have an in-hospital palliative care team who can come and speak to the patient about what is going on and address some of their needs. And I would also like to emphasize the importance of spiritual care, because for many of our patients, they are not just having the physical suffering, they are also having the spiritual suffering of hopelessness or of feeling that they are a burden or that they just are not seen because a lot of the symptoms in MS are invisible. To have that understanding by a spiritual care counselor is really helpful for the people to feel understood and to reduce some of that suffering.  Dr Grouse: That's a really great point, I think, to end on, and I think it really ties in a lot of the themes that we've been talking about today. Thank you so much for coming to talk with us today. It's been such a pleasure having you both here. Dr Smyth: Thank you. Dr Miyasaki: Thank you, Katie. Dr Grouse: Again, today I've been interviewing Drs Penelope Smyth and Janis Miyasaki about their article on palliative care in multiple sclerosis, which appears in the April 2026 Continuum issue on multiple sclerosis. Be sure to check out Continuum Audio episodes from this and other issues, and thank you to our listeners for joining today.  Dr Monteith: This is Dr. Teshamae Monteith, Associate Editor of Continuum Audio. If you've enjoyed this episode, you'll love the journal, which is full of in-depth and clinically relevant information important for neurology practitioners. Use the link in the episode notes to learn more and subscribe. AAN members, you can get CME for listening to this interview by completing the evaluation at continpub.com/audioCME. Thank you for listening to Continuum Audio.

When we talk about managing Multiple Sclerosis, our conversations naturally focus on things like disease-modifying therapies, mobility, MRI scans, and symptom management. But in this week's episode, we're shining a light on a critical aspect of MS wellness that doesn't get nearly enough attention: your oral health. Living with MS can introduce a whole host of unexpected challenges to maintaining a healthy mouth. And beyond preventing tooth decay and gum disease, emerging research suggests that chronic oral inflammation, like periodontal disease, can trigger systemic inflammation throughout the body. Dr. Ann Spolarich joins us to break down the science, explain the risks, and offer practical suggestions for maintaining oral health for people living with MS and their care partners. We're also sharing study results that revealed 1,000 differences between immune cells in men and women. (And we're explaining why that's important) If you're a parent or caregiver for a child or teen with MS, we'll tell you everything you need to know about the FDA approval of Ocrevus for treating pediatric MS. We're sharing the details of an AI partnership designed to shorten the time to an MS diagnosis and track progression in real time. We're sharing the details of another AI partnership designed to test a pill that will ease MS-related depression and fatigue. And we'll tell you about a way that you can participate in MS research from the comfort and convenience of your own home. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: The connection between your oral health and MS  :22 Study reveals 1,000 differences between men's and women's immune cells    1:30 FDA approves Ocrevus for children over the age of 10 with relapsing remitting MS  3:28 An AI partnership designed to shorten the time to an MS diagnosis and track progression in real time  5:43 An AI partnership to test a pill that will ease MS-related depression and fatigue  9:24 An opportunity to participate in MS research from the comfort and convenience of your own home  13:16 Dr. Ann Spolarich discusses the connection between your oral health and MS  13:16 Share this episode  29:45 Next week  30:05 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/455 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes at www.RealTalkMS.com STUDY: The Impact of Sex on the Immune System Explored at the Single-Cell Level https://www.cell.com/ajhg/fulltext/S0002-9297(26)00153-9 ONLINE SURVEY: Bladder-Related Fall Risk in People with MS https://www.nationalmssociety.org/how-you-can-help/get-involved/participate-in-research-studies/rs-bladder-fall-risk JOIN: The RealTalk MS Facebook Group https://facebook.com/groups/realtalkms REVIEW: Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on X, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 455 Guest: Dr. Ann Spolarich Privacy Policy

What if all the mistakes you've made, the shame you've carried and the terrible way you have treated yourself, are all part of the journey back to who you truly are. My ex-husband always used to say, "Sometimes we have to go to the wrong place to get to the right place” and he was right. And no, the irony is not lost on me ;)  The newest episode of Heal with Kelly is near and dear to my heart because I sit down with my beautiful friend Jamie Lynn Sigler — beloved for her role as Meadow Soprano in HBO's The Soprano's.  We dive into her powerful new book out this week called  And So It Is... A Memoir of Acceptance and Hope. Jamie is incredibly brave and raw in her writing.  She shares with radical honesty and humility and her story rocked me to my core while lighting me up with hope and compassion.  Jamie has lived with Multiple Sclerosis (and Lyme) for 25 years. For most of that time, she hid it — from directors, from co-stars, from the world. Before her diagnosis, she hid an eating disorder and a suffocating shame that wasn't even hers.  She shares what those years of silence cost her, and how finally telling the truth, the most courageous act one can do, actually set her free.  I cried so many times reading Jamie's new book. I saw myself in so much of her story and her journey is truly gripping, heartbreaking, and full of miracles. I could not recommend this book more.   In this episode we go deep on the inner voice that intends to protect us but turns out to be far more harmful than any external enemy. We discuss the way shame cripples our sense of worth and what it actually looks like to stop performing and start living. Jamie opens up about her son Beau's near-death experience — and the message he brought back that became her lighthouse. She shares the moment she fell to her knees in a hospital hallway and felt, for the first time, that she was not alone. And she talks about what it means to finally walk into a room and say: this is how I move. This is who I am.   This conversation is about surrender and breakthrough, plant medicine and prayer, generational healing and the stories we carry in our bodies. It's a reminder that healing is never about fixing what's broken — it's about remembering who you are beneath everything you've been told to hide. Key Moments You'll Love ✨ :

Sign up for the ultimate book club here! --------Thank you for listening! Your support of Joni and Friends helps make this show possible. Joni and Friends envisions a world where every person with a disability finds hope, dignity, and their place in the body of Christ. Become part of the global movement today at www.joniandfriends.org. Find more encouragement on Instagram, TikTok, Facebook, and YouTube.

Have you ever wondered how truly powerful your mind is? We all hear different stories about the “Power of the Mind” but have you experienced that in your own life? Personally, I used my “mind” to heal from a stroke and heart failure, all of which happened in a single year, 2020. And, as I was healing I was searching Youtube for inspirational videos and stories. I had never even taken so much as a prescription until my ordeals and I was wondering and searching for, “How do I heal myself beyond what modern medicine says I can do? I came across a video by a man named Bob Cafaro and it was titled, “The Psychology Of Beating An Incurable Disease.” The title sucked me in immediately and the video did not disappoint. As a far of matter, it was the single most impactful video that I watched. Bob healed himself from an incurable disease, Multiple Sclerosis. You read that right. He headed himself 100% using the power of his mind. I'm ecstatic because I'm visiting with Bob in this episode and he shares the specific activities that healed him. Before I talked to him, I was blown away because as we were talking, he shared how he “did the impossible,” literally. So, how does the interview apply to you and help you live a better life? Easy, if you're in any way physically ill listening to this podcast episode can do one of the most important things you ever do and if you've never been in such circumstances, Bob demonstrates the power of doing the impossible.