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En este episodio, profundizamos en uno de los fenómenos más devastadores pero menos comprendidos en neurorrehabilitación: la denervación muscular tras una lesión medular. A través de una revisión exhaustiva de la literatura científica y de la experiencia clínica, abordamos qué ocurre realmente con los músculos que han perdido su inervación, cómo se transforman con el tiempo y qué posibilidades tenemos para intervenir. Hablamos sobre neurofisiología, degeneración axonal, fases de la denervación, y cómo la estimulación eléctrica —especialmente con pulsos largos— puede modificar el curso degenerativo incluso años después de la lesión. Exploramos también el Proyecto RISE, los protocolos clínicos actuales y las implicaciones terapéuticas reales de aplicar electroestimulación en músculos completamente denervados. Si trabajas en neurorrehabilitación o te interesa la ciencia aplicada a la recuperación funcional, este episodio es para ti. Referencias del episodio: 1. Alberty, M., Mayr, W., & Bersch, I. (2023). Electrical Stimulation for Preventing Skin Injuries in Denervated Gluteal Muscles-Promising Perspectives from a Case Series and Narrative Review. Diagnostics (Basel, Switzerland), 13(2), 219. https://doi.org/10.3390/diagnostics13020219 (https://pubmed.ncbi.nlm.nih.gov/36673029/). 2. Beauparlant, J., van den Brand, R., Barraud, Q., Friedli, L., Musienko, P., Dietz, V., & Courtine, G. (2013). Undirected compensatory plasticity contributes to neuronal dysfunction after severe spinal cord injury. Brain : a journal of neurology, 136(Pt 11), 3347–3361. https://doi.org/10.1093/brain/awt204 (https://pubmed.ncbi.nlm.nih.gov/24080153/). 3. Bersch, I., & Fridén, J. (2021). Electrical stimulation alters muscle morphological properties in denervated upper limb muscles. EBioMedicine, 74, 103737. https://doi.org/10.1016/j.ebiom.2021.103737 (https://pubmed.ncbi.nlm.nih.gov/34896792/). 4. Bersch, I., & Mayr, W. (2023). Electrical stimulation in lower motoneuron lesions, from scientific evidence to clinical practice: a successful transition. European journal of translational myology, 33(2), 11230. https://doi.org/10.4081/ejtm.2023.11230 (https://pmc.ncbi.nlm.nih.gov/articles/PMC10388603/). 5. Burnham, R., Martin, T., Stein, R., Bell, G., MacLean, I., & Steadward, R. (1997). Skeletal muscle fibre type transformation following spinal cord injury. Spinal cord, 35(2), 86–91. https://doi.org/10.1038/sj.sc.3100364 (Burnham, R., Martin, T., Stein, R., Bell, G., MacLean, I., & Steadward, R. (1997). Skeletal muscle fibre type transformation following spinal cord injury. Spinal cord, 35(2), 86–91. https://doi.org/10.1038/sj.sc.3100364). 6. Carlson B. M. (2014). The Biology of Long-Term Denervated Skeletal Muscle. European journal of translational myology, 24(1), 3293. https://doi.org/10.4081/ejtm.2014.3293 (https://pubmed.ncbi.nlm.nih.gov/26913125/). 7. Carraro, U., Boncompagni, S., Gobbo, V., Rossini, K., Zampieri, S., Mosole, S., Ravara, B., Nori, A., Stramare, R., Ambrosio, F., Piccione, F., Masiero, S., Vindigni, V., Gargiulo, P., Protasi, F., Kern, H., Pond, A., & Marcante, A. (2015). Persistent Muscle Fiber Regeneration in Long Term Denervation. Past, Present, Future. European journal of translational myology, 25(2), 4832. https://doi.org/10.4081/ejtm.2015.4832 (https://pubmed.ncbi.nlm.nih.gov/26913148/). 8. Chandrasekaran, S., Davis, J., Bersch, I., Goldberg, G., & Gorgey, A. S. (2020). Electrical stimulation and denervated muscles after spinal cord injury. Neural regeneration research, 15(8), 1397–1407. https://doi.org/10.4103/1673-5374.274326 (https://pubmed.ncbi.nlm.nih.gov/31997798/). 9. Ding, Y., Kastin, A. J., & Pan, W. (2005). Neural plasticity after spinal cord injury. Current pharmaceutical design, 11(11), 1441–1450. https://doi.org/10.2174/1381612053507855 (https://pmc.ncbi.nlm.nih.gov/articles/PMC3562709/). 10. Dolbow, D. R., Bersch, I., Gorgey, A. S., & Davis, G. M. (2024). The Clinical Management of Electrical Stimulation Therapies in the Rehabilitation of Individuals with Spinal Cord Injuries. Journal of clinical medicine, 13(10), 2995. https://doi.org/10.3390/jcm13102995 (https://pubmed.ncbi.nlm.nih.gov/38792536/). 11. Hofer, C., Mayr, W., Stöhr, H., Unger, E., & Kern, H. (2002). A stimulator for functional activation of denervated muscles. Artificial organs, 26(3), 276–279. https://doi.org/10.1046/j.1525-1594.2002.06951.x (https://pubmed.ncbi.nlm.nih.gov/11940032/). 12. Kern, H., Hofer, C., Mödlin, M., Forstner, C., Raschka-Högler, D., Mayr, W., & Stöhr, H. (2002). Denervated muscles in humans: limitations and problems of currently used functional electrical stimulation training protocols. Artificial organs, 26(3), 216–218. https://doi.org/10.1046/j.1525-1594.2002.06933.x (https://pubmed.ncbi.nlm.nih.gov/11940016/). 13. Kern, H., Salmons, S., Mayr, W., Rossini, K., & Carraro, U. (2005). Recovery of long-term denervated human muscles induced by electrical stimulation. Muscle & nerve, 31(1), 98–101. https://doi.org/10.1002/mus.20149 (https://pubmed.ncbi.nlm.nih.gov/15389722/). 14. Kern, H., Rossini, K., Carraro, U., Mayr, W., Vogelauer, M., Hoellwarth, U., & Hofer, C. (2005). Muscle biopsies show that FES of denervated muscles reverses human muscle degeneration from permanent spinal motoneuron lesion. Journal of rehabilitation research and development, 42(3 Suppl 1), 43–53. https://doi.org/10.1682/jrrd.2004.05.0061 (https://pubmed.ncbi.nlm.nih.gov/16195962/). 15. Kern, H., Carraro, U., Adami, N., Hofer, C., Loefler, S., Vogelauer, M., Mayr, W., Rupp, R., & Zampieri, S. (2010). One year of home-based daily FES in complete lower motor neuron paraplegia: recovery of tetanic contractility drives the structural improvements of denervated muscle. Neurological research, 32(1), 5–12. https://doi.org/10.1179/174313209X385644 (https://pubmed.ncbi.nlm.nih.gov/20092690/). 16. Kern, H., & Carraro, U. (2014). Home-Based Functional Electrical Stimulation for Long-Term Denervated Human Muscle: History, Basics, Results and Perspectives of the Vienna Rehabilitation Strategy. European journal of translational myology, 24(1), 3296. https://doi.org/10.4081/ejtm.2014.3296 (https://pmc.ncbi.nlm.nih.gov/articles/PMC4749003/). 17. Kern, H., Hofer, C., Loefler, S., Zampieri, S., Gargiulo, P., Baba, A., Marcante, A., Piccione, F., Pond, A., & Carraro, U. (2017). Atrophy, ultra-structural disorders, severe atrophy and degeneration of denervated human muscle in SCI and Aging. Implications for their recovery by Functional Electrical Stimulation, updated 2017. Neurological research, 39(7), 660–666. https://doi.org/10.1080/01616412.2017.1314906 (https://pubmed.ncbi.nlm.nih.gov/28403681/). 18. Kern, H., & Carraro, U. (2020). Home-Based Functional Electrical Stimulation of Human Permanent Denervated Muscles: A Narrative Review on Diagnostics, Managements, Results and Byproducts Revisited 2020. Diagnostics (Basel, Switzerland), 10(8), 529. https://doi.org/10.3390/diagnostics10080529 (https://pubmed.ncbi.nlm.nih.gov/32751308/). 19. Ko H. Y. (2018). Revisit Spinal Shock: Pattern of Reflex Evolution during Spinal Shock. Korean journal of neurotrauma, 14(2), 47–54. https://doi.org/10.13004/kjnt.2018.14.2.47 (https://pubmed.ncbi.nlm.nih.gov/30402418/). 20. Mittal, P., Gupta, R., Mittal, A., & Mittal, K. (2016). MRI findings in a case of spinal cord Wallerian degeneration following trauma. Neurosciences (Riyadh, Saudi Arabia), 21(4), 372–373. https://doi.org/10.17712/nsj.2016.4.20160278 (https://pmc.ncbi.nlm.nih.gov/articles/PMC5224438/). 21. Pang, Q. M., Chen, S. Y., Xu, Q. J., Fu, S. P., Yang, Y. C., Zou, W. H., Zhang, M., Liu, J., Wan, W. H., Peng, J. C., & Zhang, T. (2021). Neuroinflammation and Scarring After Spinal Cord Injury: Therapeutic Roles of MSCs on Inflammation and Glial Scar. Frontiers in immunology, 12, 751021. https://doi.org/10.3389/fimmu.2021.751021 (https://pubmed.ncbi.nlm.nih.gov/34925326/). 22. Schick, T. (Ed.). (2022). Functional electrical stimulation in neurorehabilitation: Synergy effects of technology and therapy. Springer. https://doi.org/10.1007/978-3-030-90123-3 (https://link.springer.com/book/10.1007/978-3-030-90123-3). 23. Swain, I., Burridge, J., & Street, T. (Eds.). (2024). Techniques and technologies in electrical stimulation for neuromuscular rehabilitation. The Institution of Engineering and Technology. https://shop.theiet.org/techniques-and-technologies-in-electrical-stimulation-for-neuromuscular-rehabilitation 24. van der Scheer, J. W., Goosey-Tolfrey, V. L., Valentino, S. E., Davis, G. M., & Ho, C. H. (2021). Functional electrical stimulation cycling exercise after spinal cord injury: a systematic review of health and fitness-related outcomes. Journal of neuroengineering and rehabilitation, 18(1), 99. https://doi.org/10.1186/s12984-021-00882-8 (https://pubmed.ncbi.nlm.nih.gov/34118958/). 25. Xu, X., Talifu, Z., Zhang, C. J., Gao, F., Ke, H., Pan, Y. Z., Gong, H., Du, H. Y., Yu, Y., Jing, Y. L., Du, L. J., Li, J. J., & Yang, D. G. (2023). Mechanism of skeletal muscle atrophy after spinal cord injury: A narrative review. Frontiers in nutrition, 10, 1099143. https://doi.org/10.3389/fnut.2023.1099143 (https://pubmed.ncbi.nlm.nih.gov/36937344/). 26. Anatomical Concepts: https://www.anatomicalconcepts.com/articles
Tennessee representative Mark White tells Memphis Morning News' Ditch & Tim Van Horn modifications to his bill that could give an appointed oversight board the ability to veto MSCS actions in such things as the budget. The advisory board members would be from Shelby County. White also answered questions regarding his vote in favor of HB855 Support the show: https://www.newstalk989.com/personalities/memphis-morning-news/See omnystudio.com/listener for privacy information.
Continuing our celebration of Occupational Therapy Month, this week we chat with FOX Rehabilitation's Cristina Klymasz, MS, OTR/L, CBIS, RYT, CLT-LANA, MSCS, who talks about incorporating yoga into her occupational therapy sessions. Cristina details how a team morale event at a yoga studio made her realize how much it could benefit her patients. Being the go-getter she is, Cristina got her yoga license—not with dreams of opening her studio—but with the main intent of helping her patients. Cristina admits some patients are skeptical when the concept of yoga is brought up. Still, the results are turning doubters into believers, especially with its numerous benefits, including helping patients with their balance. Cristina also discusses how she will be spending Occupational Therapy Month and what kind of personality generally gravitates to being an OT.
Continuing our celebration of Occupational Therapy Month, this week we chat with FOX Rehabilitation's Cristina Klymasz, MS, OTR/L, CBIS, RYT, CLT-LANA, MSCS, who talks about incorporating yoga into her occupational therapy sessions. Cristina details how a team morale event at a yoga studio made her realize how much it could benefit her patients. Being the go-getter she is, Cristina got her yoga license—not with dreams of opening her studio—but with the main intent of helping her patients. Cristina admits some patients are skeptical when the concept of yoga is brought up. Still, the results are turning doubters into believers, especially with its numerous benefits, including helping patients with their balance. Cristina also discusses how she will be spending Occupational Therapy Month and what kind of personality generally gravitates to being an OT.
Continuing our celebration of Occupational Therapy Month, this week we chat with FOX Rehabilitation's Cristina Klymasz, MS, OTR/L, CBIS, RYT, CLT-LANA, MSCS, who talks about incorporating yoga into her occupational therapy sessions. Cristina details how a team morale event at a yoga studio made her realize how much it could benefit her patients. Being the go-getter she is, Cristina got her yoga license—not with dreams of opening her studio—but with the main intent of helping her patients. Cristina admits some patients are skeptical when the concept of yoga is brought up. Still, the results are turning doubters into believers, especially with its numerous benefits, including helping patients with their balance. Cristina also discusses how she will be spending Occupational Therapy Month and what kind of personality generally gravitates to being an OT.
MSCS board member, Towanna Murphy, issued an apology for threatening to deport a Hispanic woman who called her the 'b-word" and attacked her work on the school board. We break down everything revealed in the messages, and why this makes her and the MSCS look even worse. Also on the show, the stock market boomed after President Trump delayed tariffs on everyone except China. Now, China is playing tough and we react to what Mr. Wonderful's move would be if he were in charge. We also listen to today's Wheel of Weird story, "Waste of Space". See omnystudio.com/listener for privacy information.
The job to have these days is the interim superintendent role for MSCS, where Dr. Roderick Richmond could end up earning nearly half a million dollars for 18 months. The MSCS board will meet tomorrow to vote on it, but is that much money really necessary for a role that has no incentives to perform well? Also on the show, we react to Cory Booker nearly 24-hour ramble on the Senate floor, and we play two epic rounds of Impossible Memphis Trivia. See omnystudio.com/listener for privacy information.
As Memphis Shelby County Schools face a state intervention because of how they made decisions to remove the wildly popular superintendent, Dr. Marie Feagins, County Commissioner Mick Wright called in to Memphis Morning News to discuss creating an advisory group. Support the show: https://www.newstalk989.com/personalities/memphis-morning-news/See omnystudio.com/listener for privacy information.
Learn about the 3 hallmarks of aging here.https://www.alluremedical.com/the-3-hallmarks-of-aging/Dr. Charles Mok discusses the potential of stem cell therapy in strengthening joints and addressing arthritis without the need for joint replacement. He provides an in-depth exploration of mesenchymal stem cells (MSCs), naturally found in body tissues, and their regenerative properties.Originally developed for cancer treatment, stem cells have since been studied for various therapeutic applications. He explains the different types of stem cells, their mechanisms of action, and the techniques used to harvest them from the body. He also examines their role in treating chronic conditions, promoting longevity, and reducing inflammation associated with joint degeneration.Dr. Mok reviews clinical studies demonstrating the positive effects of stem cell therapy and also discusses the success rates and the best options for individuals considering this treatment.Tune in to the Inside The Cure Podcast — Get Stronger Joints with Stem Cell Therapy————————————————————————————————Subscribe to Inside the Cure on Apple Podcasts and leave a 5-star review! https://podcasts.apple.com/us/podcast/inside-the-cure-with-dr-charles-mok/id1495870043?uo=4Read the latest research and advice from Allure Medical: https://www.alluremedical.com/books/ Dr. Charles Mok received his medical degree from Chicago College of Osteopathic Medicine, Chicago, Illinois in 1989. He completed his medical residency at Mount Clemens General Hospital, Mt. Clemens, Michigan. He has worked with laser manufacturing companies to improve their technologies; he has performed clinical research studies and has taught physicians from numerous other states. His professionalism and personal attention to detail have contributed to the success of one of the first medical spas in Michigan.LinkedIn: https://www.linkedin.com/in/charles-mok-4a0432114/Instagram: https://www.instagram.com/alluremedicals/Website: https://www.alluremedical.com/YouTube: https://www.youtube.com/@AllureMedical Amazon Store: https://www.amazon.com/stores/Dr.-Charles-Mok/author/B0791M9FZQ?ref=ap_rdr&store_ref=ap_rdr&isDramIntegrated=true&shoppingPortalEnabled=true #StemCellTherapy #Arthritis #ArthritisTreatment #RegenerativeMedicine #JointHealth #LongLife #HealthyJoints #Longevity #StemCells #MedicalResearch #HealthPodcast
Episode Notes My guests include State Senator Raumesh Akbari. With so much on the table affecting both Memphis and Shelby County, this legislative session has faced intense focus. She joins me to discuss a state possible takeover of the MSCS Board, the threat to withhold state tax revenue to the tune of $75 million dollars if Memphis moves forward with gun control legislation and how a bill she is co-sponsoring could help fund a new jail. Next, we often hear about the role fathers play in a child's life. Antonio Harvey is the founder and Executive Director of Fathers First Memphis whose mission is to cultivate nurturing and engaged fathers who will enhance the well-being of children. He joins me to discuss its importance and a new partnership with MSCS. That and more, on air and online Monday nite on WYXR 91.7 FM. Also, the WYXR app, Tunein, Facebook Live, YouTube and wherever you get your podcasts.It's time to talk!
Episode Notes My guests include State Senator Raumesh Akbari. With so much on the table affecting both Memphis and Shelby County, this legislative session has faced intense focus. She joins me to discuss a state possible takeover of the MSCS Board, the threat to withhold state tax revenue to the tune of $75 million dollars if Memphis moves forward with gun control legislation and how a bill she is co-sponsoring could help fund a new jail. Next, we often hear about the role fathers play in a child's life. Antonio Harvey is the founder and Executive Director of Fathers First Memphis whose mission is to cultivate nurturing and engaged fathers who will enhance the well-being of children. He joins me to discuss its importance and a new partnership with MSCS. That and more, on air and online Monday nite on WYXR 91.7 FM. Also, the WYXR app, Tunein, Facebook Live, YouTube and wherever you get your podcasts. It's time to talk!
Episode Notes My guests include State Senator Raumesh Akbari. With so much on the table affecting both Memphis and Shelby County, this legislative session has faced intense focus. She joins me to discuss a state possible takeover of the MSCS Board, the threat to withhold state tax revenue to the tune of $75 million dollars if Memphis moves forward with gun control legislation and how a bill she is co-sponsoring could help fund a new jail. Next, we often hear about the role fathers play in a child's life. Antonio Harvey is the founder and Executive Director of Fathers First Memphis whose mission is to cultivate nurturing and engaged fathers who will enhance the well-being of children. He joins me to discuss its importance and a new partnership with MSCS. That and more, on air and online Monday nite on WYXR 91.7 FM. Also, the WYXR app, Tunein, Facebook Live, YouTube and wherever you get your podcasts. It's time to talk!
Shelby County Commissioners Mickell Lowery and Britney Thornton talked on “Behind The Headlines” about the political boundary between the commission and the MSCS board.
Episode Notes My guests include County Commissioner Mick Wright. He was one of many who disagreed with the MSCS school board in terminating Dr. Marie Feagins. He and a number of his fellow colleagues backed a resolution of no confidence in the board prior to the vote and now the stage is set for a state takeover. I ask him whether he is for or against the move. Next, the President has made it his mission to remove undocumented immigrants from this country for criminal behavior, but does it stop there? Andrew Rankin, ESQ is a local Immigration Atty who is working with many in the Mid South who are very concerned about their future and what might happen to themselves and their families. He explains the options. Lastly, are you familiar with the expression Mane Up? I speak with Racheal Shantal, Executive director of Mane UP Memphis. It's a non-profit organization that helps empower youth and families through mental health services and financial literacy programs. She tells me why programs like this are so vitally important for the future of our community. That and more on air and online Monday nite, 6 pm on 91.7 WYXR. Also, the WYXR app, Tunein, Facebook Live, YouTube and wherever you get your podcasts! It's time to talk.
Episode Notes My guests include County Commissioner Mick Wright. He was one of many who disagreed with the MSCS school board in terminating Dr. Marie Feagins. He and a number of his fellow colleagues backed a resolution of no confidence in the board prior to the vote and now the stage is set for a state takeover. I ask him whether he is for or against the move. Next, the President has made it his mission to remove undocumented immigrants from this country for criminal behavior, but does it stop there? Andrew Rankin, ESQ is a local Immigration Atty who is working with many in the Mid South who are very concerned about their future and what might happen to themselves and their families. He explains the options. Lastly, are you familiar with the expression Mane Up? I speak with Racheal Shantal, Executive director of Mane UP Memphis. It's a non-profit organization that helps empower youth and families through mental health services and financial literacy programs. She tells me why programs like this are so vitally important for the future of our community. That and more on air and online Monday nite, 6 pm on 91.7 WYXR. Also, the WYXR app, Tunein, Facebook Live, YouTube and wherever you get your podcasts! It's time to talk.
The “Behind The Headlines” reporters roundtable also reviewed the end of the Tennessee Legislature's special session and the change Regional One Health's new plans.
DEI has been the topic of discussion for good reason because the Trump administration put out an executive order for companies and organizations to get rid of DEI programs indefinitely. MSCS school board has a new superintendent but the State of TN still plans to take over, Tia Mowry had a change of heart with ex-husband Cory Hardict, Chiefs/Eagles Super Bowl, Cowboys hire a new coach and plenty more. #dei #trumpadministration #tiamowry #superbowl Checkout this episode's show on YouTube: https://youtube.com/live/OGuh-gM2ffQDon't forget to catch up on past episodes and run downs on our YouTube channel: https://www.youtube.com/@ThePrezExTVBe sure to SUBSCRIBE and LIKE the videos!Follow us on Instagram: https://www.instagram.com/theprezexLike us on Facebook: https://www.facebook.com/theprezexSend all requests and business inquiries via Email: theprezex@gmail.com
47 wasted no time for action after being inaugurated, Dave Chappelle with another classic on SNL and MSCS superintendent Dr. Feagins is potentially on the chopping block (again) from being terminated. And of course we have a rundown of quickies from the NFL playoffs to the woman who slept with 1,000 men in 12 hours. #theprezex #inauguration #snl Checkout this episode's show on YouTube: https://youtube.com/live/ogYXcWLzix8Don't forget to catch up on past episodes and run downs on our YouTube channel: https://www.youtube.com/@ThePrezExTVBe sure to SUBSCRIBE and LIKE the videos!Follow us on Instagram: https://www.instagram.com/theprezexLike us on Facebook: https://www.facebook.com/theprezexSend all requests and business inquiries via Email: theprezex@gmail.com
'This is the real reason MSCS fired Dr. Feagins': K. Durell Cowan
Lawsuits are looming all over the city as Dr. Feagins looks to take MSCS to court after getting fired, Speaker Cameron Sexton confirming the state could take over the MSCS board, and the board now threating to file a lawsuit if the state were to take over. It's a dumpster fire, and local lawyers are gonna eat good this year. Also on the show, we break down the deportations moves Trump made against Columbia over the weekend, and we react to the Kansas City Chiefs heading back to the Super Bowl. See omnystudio.com/listener for privacy information.
Speaker Sexton Says State WILL Takeover MSCS and Declare Board 'Null and Void'
The board has spoken. Following an emotional, contentious, and lengthy public school board meeting, Dr. Marie Feagins was fired as the superintendent of Memphis-Shelby County Schools on Tuesday night and we break it all down for you. Also on the show, we go over what our listeners would sign as executive orders like fines for not flushing the toilet at work and we try to find who has the highest mileage in their vehicles. Some were flirting with 500k!See omnystudio.com/listener for privacy information.
0:00 start/set the show6:00 Snow in odd places9:00 Finale of the MSCS Board meeting25:00 Grizzlies v. Hornets34:00 Jimmy Butler saga37:00 MLB Hall of Fame class of '2538:00 LeBron's triple-double43:00 DeAngelo Williams1:09:00 STORY TIME1:17:00 Baby Shower etiquette1:23:00 Dan Hurley gotta let 'em know1:27:00 ATL airport issues
It's the second day of Trump's term and during what was supposed to be a prayer ceremony for the President, it turned into an LGBTQ lecture from an activist bishop with a long history of TDS. Also on the show, Dr. Marie Feagins' future is decided tonight by the MSCS, and we play Impossible Tuesday Trivia and Jake got perhaps the most difficult card yet. See omnystudio.com/listener for privacy information.
Mesenchymal stem cells (MSCs) are multipotent adult stem cells which can differentiate into multiple cell types. MSCs can be isolated from the bone marrow, umbilical cord blood, adipose tissue, muscle, and dental pulp. However, the use of these MSCs involves a number of barriers. Human umbilical cord is limited to collection at birth. Bone marrow and fat biopsy are painful and requires general anesthesia. If only there was an easily obtainable method to collect these MSCs, like maybe even once a month, collectable in a little cup, without biopsy. WHAT… use menstrual blood you say?! Menstrual blood-derived mesenchymal stem cells (MenSCs) were first described by Meng et al. in 2007, as a novel source of MSCs. Most of the MenSC are produced by the endometrium. With the potential of multi-directional differentiation, this has spurred a list of preclinical and animal studies looking into the collection of menstrual blood for MSC processing. Men SCs have been investigated for use in Alzheimer's disease, Stroke, Spinal Cord Injury, Type I DM, wound healing, endometriosis therapy, infertility, and even Muscular Dystrophy. Is there a miracle med in menses? Listen in for details.
Three Shelby County commissioners who supported a no-confidence vote aimed at Memphis-Shelby County Schools board members talked on “Behind The Headlines” about the ongoing standoff between the school board and its superintendent.
BUFFALO, NY- January 14, 2025 – A new #research paper was #published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 22 on November 26, 2024, entitled “When do the pathological signs become evident? Study of human mesenchymal stem cells in MDPL syndrome.” Researchers from the University of Rome Tor Vergata, Fondazione Policlinico Tor Vergata, Roma Tre University, and Meyer Children's Hospital IRCCS have identified early cellular changes associated with Mandibular Hypoplasia, Deafness, Progeroid Features, and Lipodystrophy (MDPL) syndrome, a rare genetic aging disorder caused by a mutation in the POLD1 gene. MDPL leads to fat loss, distinct facial features, and metabolic disturbances. This study aimed to better understand how MDPL progresses at the cellular level. MDPL syndrome is extremely rare, with only a few documented cases worldwide, making it difficult to study. To investigate the disease, researchers Spitalieri Paola, Guerrieri Lara, Murdocca Michela, Di Cesare Silvia, Maccaroni Serena, Pecorari Rosalba, Nardone Anna Maria, Candi Eleonora, Colasuonno Fiorella, Gori Giulia, Traficante Giovanna, Novelli Giuseppe, and Sangiuolo Federica, converted skin cells from three female MDPL patients and two healthy donors into human induced pluripotent stem cells (hiPSCs). These hiPSCs were then transformed into mesenchymal stem cells (MSCs), cells that can form tissues like bone and fat, which are primarily affected in MDPL syndrome. The study revealed that MSCs from MDPL patients exhibited signs of premature aging much earlier than expected. The cells had irregular shapes, grew at a slower rate, and showed higher levels of cellular stress. “These cells differentiate with lower efficiency, proliferate more slowly and have abnormal mitochondrial activity with increased production of ROS. Furthermore, the telomeres show evident shortening.” All the findings suggest that aging-related changes may occur long before patients display visible symptoms of the disease. This highlights the need for early diagnosis and intervention, which could delay or even prevent the most debilitating effects of MDPL syndrome. In summary, this study offers new perspectives on the initial cellular impacts of MDPL, opening the door for the creation of novel treatments. The findings highlight the potential for personalized therapies and emphasize the critical role of lab-created hiPSCs in advancing research on rare genetic diseases and age-related conditions. DOI - https://doi.org/10.18632/aging.206159 Corresponding author - Sangiuolo Federica - sangiuolo@med.uniroma2.it Video short - https://www.youtube.com/watch?v=DLXD2ztPTm0 Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206159 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, MDPL syndrome, MSCs, hiPSCs, POLD1 gene About Aging-US The mission of the journal is to understand the mechanisms surrounding aging and age-related diseases, including cancer as the main cause of death in the modern aged population. The journal aims to promote 1) treatment of age-related diseases by slowing down aging, 2) validation of anti-aging drugs by treating age-related diseases, and 3) prevention of cancer by inhibiting aging. (Cancer and COVID-19 are age-related diseases.) Please visit our website at https://www.Aging-US.com and connect with us: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM
Episode Notes My guests include prominent employment attorney Alan Crone who is representing Dr. Marie Feagins in her case against being terminated by the MSCS board. He explains why he feels the case against her is not supported by fact. Next, MSCS Board Member Amber Huett-Garcia joins me to discuss the termination effort by some of her colleagues against the Superintendent. She disagrees with that and tells me about a proposal she has drafted that she hopes will turn down the temperature on both sides. Finally, many of you have noticed that several restaurants closed last year disappointing many patrons. Memphis Restaurant Association member Arturo Azcarate, owner of Curry N Jerk joins me to talk about the reasons and to tell us about some of the new spots we can expect to tickle our tastebuds. That and more both on air and online, Monday, 6pm on WYXR 91.7 FM. Also, WYXR.org, Tunein, Facebook Live, YouTube and wherever you get your podcasts. It's time to talk!
About Dr Adeel Khan, MD - CEO and Founder of Eterna Health Interventional Cell and GeneTherapy Specialist: Dr. Adeel Khan, MD, is a trailblazer in regenerative medicine, transforming how we think about health, longevity, and recovery. As a Canadian Board-Certified Physician, Dr. Khan has pioneered cutting-edge therapies using stem cells and peptides—modalities now making headlines around the globe. Recognized worldwide, Dr. Khan's impact resonates among healthcare professionals, elite athletes, and individuals from diverse walks of life. His groundbreaking treatments have earned him the trust of renowned figures, including celebrities, such as Chris Hemsworth, life coach Tony Robbins, Chris Bumstead (popularly known as “cbum,” a top fitness influencer), and Mohamed Alabbar, the visionary developer behind the iconic Burj Khalifa. Dr. Khan's work is being discussed across major media outlets, with a focus on the potential of stem cell therapies to redefine healthcare. His ability to deliver real results is changing the conversation on what's possible in modern medicine. Dr. Khan's unwavering dedication to understanding cellular physiology and the art of cellular repair has led to collaborations with scientists in Canada, the USA, Mexico, Dubai, Italy, and Japan. These partnerships have helped shape Eterna Health, a revolutionary concept in specialized healthcare offering unparalleled treatment options that stand out in the medical landscape. Connect with Dr. Khan: Website: Eterna Health Instagram: @dr.akhan YouTube: Doctor Adeel Episode Summary: In this episode, Dr. Cassie Smith hosts Dr. Adeel Khan, a Canadian board-certified physician specializing in regenerative medicine, to discuss stem cells. Dr. Khan explains the unique properties of stem cells, particularly mesenchymal stem cells (MSCs), and their potential to treat chronic diseases, aging, and cosmetic issues. The conversation covers the science behind stem cells, their therapeutic applications, and the limitations of conventional medicine. Dr. Khan also addresses ethical concerns, regulatory challenges, and the future of stem cell research, emphasizing the transformative potential of regenerative medicine. Show Highlights: (00:02:35) Frustration with Conventional Medicine (00:04:46) Understanding Stem Cells (00:05:49) The Role of Stem Cells in Healing (00:06:27) Stem Cells and Aging (00:11:34) Clinical Applications of Stem Cells (00:14:54) Common Uses for Stem Cell Treatments (00:16:13) Stem Cells are Transforming Cosmetic Procedures (00:18:36) Stem Cells are the Body's Super Repairman (00:19:00) Smart Stem Cells?? They're Amazing! (00:20:52) Unbelievable Patient Results with Stem Cells (00:24:39) Stem Cells for Healing Autoimmune Conditions (00:29:30) FDA Regulations on Stem Cells (00:39:02) Potential of Stem Cells in Healing (00:46:24) Can Stem Cells Render Transplants Obsolete? (00:52:04) Future of Medicine with Stem Cells Connect with Modern Endocrine: Check out the website Follow Cassie on Instagram Follow Cassie on Facebook Follow Cassie on YouTube Follow Cassie on TikTok Sign up for Modern Endocrine's newsletter Disclaimer
Send us a textIn the second part of our conversation with Andrea Gough, Senior Director for Advanced Instruments' Solentim Portfolio, we'll explore how AI and machine learning have, in recent years, begun to transform various aspects of biotechnology, including cell line development (CLD). Andrea shares insights into how these cutting-edge technologies are being applied to the early stages of clone selection.AI's capability to analyze images and classify clone viability is another breakthrough. Feeding thousands of images into AI systems allows for efficient and accurate decision-making, reducing the workload on scientists.Here are three key takeaways from our conversation:Leverage AI and Machine Learning: Integrate AI to streamline clone selection and optimize cell line development processes. AI can identify key phenotypic identifiers and predict the best clones, driving efficiency and productivity.Diversify Expression Systems: While CHO cells dominate the protein therapy space, exploring alternative systems like HEK cells, MSCs, IPSCs, and even insect cells can offer unique benefits and improve gene therapy productions.Maintain Comprehensive Documentation: Ensure rigorous tracking and documentation of all processes. From certificates of analysis to raw image data, having meticulous records will safeguard your development process and aid compliance with regulatory standards.Tune in to the full episode for more insights on overcoming challenges in cell line development and tips for setting up successful bioprocessing workflows!Connect with Andrea GoughLinkedIn: www.linkedin.com/in/andrea-gough-72915282Advanced Instruments: www.aicompanies.comNext Steps:Wondering how to develop cell and gene therapies with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessmentDevelop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at hello@bruehlmann-consulting.com
Donald Trump said on Tuesday that he would not rule out the use of military force to seize control of Greenland. Predictably, the media ran with the twist that Trump could invade Greenland and take it from the Danish. Also on the show, Dr. Marie Feagins has stood up to the MSCS board by declaring she will not resign her position. We also play Impossible Memphis Trivia, and boy was it impossible today. See omnystudio.com/listener for privacy information.
Violent crime and efforts to battle it were among the top stories of the year as discussed in a reporters' roundtable on “Behind The Headlines.” The show also included discussion of the effort by some MSCS board members to fire school superintendent Marie Feagins and the ouster attempt by state leaders against District Attorney General Steve Mulroy.
Superintendent Dr. Marie Feagins continues to be on the hot seat as the MSCS Board still want her out. Well Memphians were not happy with MSCS trying to kick her out, and they made sure they knew about their support for the Superintendent. Also on the show, we give you our thoughts on the Tigers winning their bowl game against West Virginia last night, and we talk about our favorite toys we got for Christmas and we take our listener's favorites as well. See omnystudio.com/listener for privacy information.
Dr. Herbert Karpatkin, PT, DSc, NCS, GCS, MSCS, joins J.J. Mowder-Tinney to share his expertise on improving mobility in patients with multiple sclerosis (MS). Herb discusses the common misconceptions about MS in physical therapy and offers practical strategies, including interval training and task-specific exercises, to enhance patient outcomes. Learning Objectives Interpret the evidence around how to improve mobility and exercise tolerance in people with MS Apply evidence-based, practical strategies to actionably address fatigue to increase exercise intensity for people with MS Solve patient case scenarios involving MS focusing on exercise, rest, and functional outcomes Timestamps (00:00:00) Welcome (00:00:58) Introduction to guest (00:03:33) Is there anything we should be questioning as clinicians in regard to people with MS? (00:08:05) What's the evidence and application? (00:16:50) Translating research into clinical practice (00:26:21) Fatigue measures and scales (00:36:21) Three actionable takeaways (00:45:00) Final words of wisdom Neuro Navigators is brought to you by Medbridge. If you'd like to earn continuing education credit for listening to this episode and access bonus takeaway handouts, log in to your Medbridge account and navigate to the course where you'll find accreditation details. If applicable, complete the post-course assessment and survey to be eligible for credit. The takeaway handout on Medbridge gives you the key points mentioned in this episode, along with additional resources you can implement into your practice right away. To hear more episodes of Neuro Navigators, visit https://www.medbridge.com/neuro-navigators If you'd like to subscribe to Medbridge, visit https://www.medbridge.com/pricing/
In this episode of Unreasonable Health, Regan Archibald dives deep into the power of rejuvenation therapy and how it can enhance vitality. He explains the importance of maintaining an optimal internal environment for MSCs to thrive, and discusses groundbreaking advances in stem cell rejuvenation. Regan shares personal experiences with this powerhouse alternative, offering insights on improving joint health, brain injuries, and reducing inflammation. Tune in to learn about optimizing your body's repair processes and take on this week's health challenge—eliminate alcohol to support stem cell function.
BUFFALO, NY - December 3, 2024 – A new #review was #published in Oncotarget's Volume 15 on November 22, 2024, entitled “Mesenchymal stem cells - the secret agents of cancer immunotherapy: Promises, challenges, and surprising twists." Authored by Theia Minev, Shani Balbuena, Jaya Mini Gill, Francesco M. Marincola, Santosh Kesari, and Feng Lin from CureScience Institute, Sonata Therapeutics, and Pacific Neuroscience Institute and Providence Saint John's Health Center, this review explores the potential role of mesenchymal stem cells (MSCs) in cancer treatment. These stem cells can naturally target tumors and deliver therapeutic agents directly to cancer cells, potentially improving treatment outcomes while reducing side effects commonly associated with traditional therapies like chemotherapy. However, the authors also note significant challenges, pointing out that under certain conditions, MSCs may unintentionally promote tumor growth, highlighting the need for careful therapeutic design. MSCs are cells that can develop in different types of tissues, such as bone, fat, or cartilage, and act as natural repair agents. What makes them particularly special is their ability to respond to biological signals, like inflammation, which is often present in cancer. This enables them to locate tumors, and once there, they can deliver cancer treatments directly to the affected area. Clinical trials are already investigating MSC-based treatments for cancers such as brain tumors, melanoma, and ovarian cancer. Some results are promising, showing that MSCs can effectively deliver treatments and boost the immune system's fight against cancer. However, other trials have also revealed the complexities of MSC behavior, including variability in their effects and the potential to create conditions that support tumor growth. “This variability may be due to the tumor immune microenvironment's effects, where immune cells are inhibited by various factors, creating a conducive environment for tumor growth.” The authors also suggest that “Developing personalized MSC therapies tailored to the specific characteristics of a patient's tumor and immune system could enhance the efficacy and safety of MSC-based treatments.” Achieving this requires a deeper understanding of how MSCs interact with cancer cells and their surrounding environment. In conclusion, this review highlights both the potential and challenges of (MSCs in cancer therapy. With ongoing research and technological advancements, MSCs could become a key component of personalized cancer treatments, offering new hope for patients worldwide. DOI - https://doi.org/10.18632/oncotarget.28672 Correspondence to - Feng Lin - flin@curescience.org Video short - https://www.youtube.com/watch?v=Wwc3zDDitlc Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ About Oncotarget Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science. Oncotarget is indexed and archived by PubMed/Medline, PubMed Central, Scopus, EMBASE, META (Chan Zuckerberg Initiative) (2018-2022), and Dimensions (Digital Science). To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM
In this episode of the Beautifully Broken podcast, host Freddie Kimmel speaks with Dr. Mattias Bernow, CEO of CellCollabs, about the potential of mesenchymal stem cells (MSCs) in regenerative medicine. They discuss how these cells combat chronic diseases, promote longevity, and why Good Manufacturing Practices (GMP) are crucial for safety and efficacy. Dr. Bernow shares insights into cardiovascular disease prevention trials, the importance of clinical research, and the decline in stem cell potency with age.The episode also examines the risks of medical tourism for stem cell treatments and highlights CellCollabs' mission to make therapies safer and more affordable globally. Dr. Bernow emphasizes the impact of lifestyle factors on health and the need to democratize access to quality stem cell treatments. With practical insights and key takeaways, this discussion sheds light on the future of healthcare and the value of investing in well-being.HIGHLIGHTSChapters00:00 Unlocking the Power of Stem Cells03:57 Understanding Stem Cells and Their Role in Healing10:01 The Science Behind Mesenchymal Stem Cells18:02 Safety and Efficacy of Stem Cell Therapies24:03 The Future of Stem Cell Therapy and Accessibility26:50 Innovations in Clinical Trials and Longevity Research30:28 The Role of Patient-Funded Trials in Advancing Medicine33:45 Lifestyle Factors Complementing Stem Cell Therapy37:58 The Importance of Community and Health Practices41:21 Understanding the Cost and Value of Stem Cell Treatments46:05 The Future of Health Investments and Corporate WellnessConnect with CellColabs: https://cellcolabs.comUPGRADE YOUR WELLNESSStemRegen: https://www.stemregen.co/products/stemregen?_ef_transaction_id=&oid=1&affid=52Code: beautifullybrokenLightPathLED https://lightpathled.pxf.io/c/3438432/2059835/25794Code: beautifullybrokenSilver Biotics Wound Healing Gel: https://bit.ly/3JnxyDDCode: BEAUTIFULLYBROKEN CONNECT WITH FREDDIE Check out my website and store: (http://www.beautifullybroken.world) Instagram: (https://www.instagram.com/beautifullybroken.world/) YouTube: (https://www.youtube.com/@BeautifullyBrokenWorld)
Have you heard some things about working with people with MS that make you question how to approach their care? Are they old school thoughts or based on science? Who can tell?! You'll know after listening to this episode! Hosts Erin Gallardo and Claire McLean had the privilege of speaking with Herb Karpatkin, PT, DSc, NCS, MSCS, a leading expert in physical therapy for individuals with multiple sclerosis (MS). Herb shared invaluable insights from his decades of clinical experience and research, providing guidance for physical therapists on how to actually support patients with this complex neurological condition so they improve. A key focus of Herb's research has been exploring ways to help MS patients overcome debilitating fatigue, which often limits their ability to participate in rehabilitation. He has found great success with intermittent training protocols, where patients alternate short bursts of activity with rest periods. Herb shares specific parameters from the research so you can use it now. Next you must recognize that a significant portion of disability in MS patients may be due to deconditioning, rather than the neurological disease process itself. By implementing targeted reconditioning programs, physical therapists can make a substantial impact on improving functional mobility, even in those with advanced disease. Herb's research has also demonstrated the benefits of high-intensity interval training for individuals with MS. Contrary to outdated beliefs, many MS patients are able to tolerate and thrive with aggressive exercise programs when implemented thoughtfully. Herb emphasizes the importance of gradually progressing patients to higher intensities, while closely monitoring for signs of fatigue. To further support the MS community, Herb is actively involved with the Degenerative Disease Special Interest Group of the American Physical Therapy Association. This group has created a Clinician Locator Map to help patients find physical therapists with expertise in treating degenerative conditions like MS. For your patients and clients with MS: MS Cooling Products Application Sign up for the clinician locator map: https://www.neuropt.org/special-interest-groups/degenerative-diseases/ddsig-clinician-locator-map Register for the free webinar on MS interventions you can apply immediately here! https://www.neurocollaborative.com/ms-webinar
Are more stem cells always better? This is the question I aim to answer in this week's episode of The Dr. Joy Kong Podcast.So many of you have asked me what I think about expanded stem cells and if they work better than native ones. Many patients come to me with a common misconception: More stem cells = Better results. However, that couldn't be farther from the truth.In fact, various studies have shown that culturing and expanding stem cells can lead to genetic alterations, reduced effectiveness, and even dangerous side effects.Listen in as I break all of this down for you and discuss the big differences between expanded and unexpanded stem cells and why I think you should always go with the latter if you can. Are you ready?Let's dive in. Key Takeaways:Introduction (00:00)Expanded cells vs unexpanded cells (01:18)How culturing reduces stem cells' potential (03:19)What happens when you expand MSCs (05:15)Why expanded stem cells are inferior (08:29)Why I use native cells (11:55)More is not always better (14:05)Additional Resources:✨ Learn more about how to live a long and pain-free life: www.drjoykong.com —Dr. Joy Kong is a regenerative medicine and anti-aging expert. Her podcast is part of her mission to reduce suffering and elevate happiness. Join us every week for the latest holistic health insights that will help you live a long and pain-free life.
MSCS superintendent Marie Feagins talked on “Behind The Headlines” about the look at closing some schools and the changes to the school system including eliminating 600 vacant positions and reassigning those in other positions.
In its final action, the former MSCS board tasked incoming members with creating a strategic plan and evaluation for Superintendent Marie Feagins.
To address the need to characterize long COVID in children and adolescents, the National Institutes of Health funded a pediatric program in the Researching COVID to Enhance Recovery (RECOVER) Initiative. Editorialist Suchitra Rao, MBBS, MSCS, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, discusses this and more with JAMA Senior Editor Tracy A. Lieu, MD, MPH. Related Content: Uncovering Long COVID in Children Characterizing Long COVID in Children and Adolescents
Send us a Text Message.It's not easy to grow a business and make it efficient. Many of us struggle to make it happen and it doesn't help that the trades are full of guys with lots of pride and stubbornness. We often times get the mindset that we have to do everything on our own and that because we know our trade well, that we know how to run our business well. Knowing your trade and knowing how to run a business are two separate skills though and we have to normalize this.Mike Somodean is the owner of MSCS Inc in Roswell Georgia. After moving from Romania in 2003, he started MSCS Inc in 2006 and hasn't looked back. Along the way he has gotten married, had a son, made the NWFA 40 under 40, and even won NWFA Floor of the Year. Mike is also a NWFA certified installer, sand and finisher, sales advisor, and regional instructor. All of these accolades help push his craft and business forward but along the way he realized he couldn't figure it all out himself and needed some help. Mike had to get out of his own way and let others step in with doing what they are best at.Listen in to this weeks episode of the Floor Academy podcast as Mike and I discuss why he hired a business coach to move his business beyond where he was at. What changes he had to make before coming to that decision, and how it has impacted his professional and personal life.Check out our sponsorsJohns ManvilleSchluter SystemsThe International Surfaces EventKronus SoftArdex AmericasTileTools.comCheck out our website and storeSupport the Show.
Explaining how the stem cells the guys got are DIFFERENT than the ones you can get in the United States. (3:04) Why are the U.S. regulators so slow? (9:09) Why he is so confident about the treatments he provides. (12:52) 1st vs. 2nd generation stem cells. (15:53) Where does he get his stem cells? (19:08) How does the average consumer know how to wean out the charlatans? (20:12) What are the Asian countries using stem cells for? (21:53) What do people typically notice when they do stem cell treatment for anti-aging/longevity? (23:11) More is better. (25:09) His belief on what stem cell therapy will do to us as a species. (26:20) Breaking down the stem cell treatments the guys got and the profound effects they've witnessed since. Adam. (28:21) Sal. (47:13) Justin. (56:12) What treatment has had the biggest impact on his patients? (59:39) In the future does he see these treatments to be affordable for the masses? (1:07:25) How does he balance his personal and professional life? (1:09:35) Wrestling with manufacturing adversity with his children. (1:16:56) Related Links/Products Mentioned Unlock Longevity event – February 24, 2024 in Austin, TX ** Promo Code MINDPUMP20 - Anyone who uses this promo code will get 20% off their ticket price. ** Special Launch: Mind Pump Fitness Coaching Course ** Promo code 200OFF at checkout for $200 off ** January Promotion: New Year's Resolutions Special Offers!! New to Weightlifting Bundle | Body Transformation Bundle | New Year Extreme Intensity Bundle Body | Transformation Bundle 2.0 Mesenchymal stem/stromal cells (MSCs): origin, immune regulation, and clinical applications How iPS cells changed the world | Nature Synthetic biology Mind Pump #1762: Tony Robbins – Life Transforming Breakthroughs In Precision Medicine Exosomal therapy—a new frontier in regenerative medicine Fecal Microbiota Transplantation: An Update on Clinical Practice Caroline GANOBIS | PhD | PhD | University of Guelph, Guelph Regenerative and Protective Actions of the GHK-Cu Peptide Sickening: How Big Pharma Broke American Health Care and How We Can Repair It – Book by John Abramson #263 - John Abramson: Big Pharma | Lex Fridman Podcast A review of vagus nerve stimulation as a therapeutic intervention The Roseto effect: a 50-year comparison of mortality rates. Mind Pump Podcast – YouTube Mind Pump Free Resources Featured Guest/People Mentioned Adeel Khan, MD (@dr.akhan) Instagram Tony Robbins (@tonyrobbins) Instagram Caroline Ganobis, PhD Matthew Wolff (@matthew_wolff5) Instagram John Abramson (@DrJohnAbramson) Twitter Lex Fridman (@lexfridman) Twitter Inky Johnson (@InkyJohnsonMotivate) Instagram Arthur Brooks (@arthurcbrooks) Instagram