Podcasts about tmbp

A rare live TMBP broadcast (recording) during the 2024 NBA All Star Game. We didn't make it to the third quarter. Oof.

On this weeks episode of TMBP, Dan is finally accepted into the Jamaican community, the Other Dan has no respect for Bradley Cooper, and both Dan's wonder if this is the time where PTA Anderson finally loses the thread in their fashionably late review of PHANTOM THREAD starring Daniel Day Lewis as a completely normal, well adjusted man, I really don't see what the problem here was

Lou Reid returns to the show after long last to talk about the Mink Car tune "Hovering Sombrero." We examine the confusing jumble of demo versions, a wacky ABC's one, some live takes and various awesome covers including one from TMBP favorites We Are Number Three.

Eve Gasse visits TMBP from that Frenchie part of Canada to bump the ranking of "Renew My Subscription" way up the TMBW song charts (be prepared to go score it on the wiki, for real). The song started as an exclusive from The Spine and then got a physical release on Venue Songs, but still has been relegated to deep cut status. Together we show you how impeccable the songwriting is, and how wild the lyrics are.    

Santa came a little late to TMBP this year, so Stephanie Cummings visited to talk about "Santa's Beard" from Lincoln. We check out the Dial-a-Song, the live debut, and try to figure out exactly what's going on with the relationship portrayed in the song. 

Merry Christmas, Happy Holidays! Ana, Ceci & Lizzie talk about their love of Christmas, boybands and why Boyband Christmas music is the ultimate Christmas music. We discuss our favorite boyband and non-boyband Christmas albums, songs and memories. We end with a recap of 2022 and the pop music that it gave us and which boybands we said a (hopefully temporary) goodbye to. TMBP's Boyband Christmas Spotify Playlist: https://open.spotify.com/playlist/7EGDNPUKsuUd1S6Hy6anTC?si=dc58d7d8cdbb445c --- Support this podcast: https://anchor.fm/boybandpod/support

It's a crossover! Optometrist and podcaster Andrew May is on the show to talk about "Dr. Sy Fly" from The Escape Team to coincide with my appearance on Andrew's Daily Five where we talk about my top ten bands of all time throughout this week. Here on TMBP we manage to get into lots of TMBG-related lists before we break down this little Linnell ditty, and hear a parody cover from Andrew himself.    To hear the first episode of my appearance on Andrew's Daily Five click here! To hear Andrew's cover parody of the song, check it out on Apple Music and Spotify!

Glory McElheny makes her TMBP debut to talk about the undisputed banger "Metal Detector" off of Factory Showroom. We talk about the book Buried Treasure of Casco Bay which inspired the song, actual metal detectors, and moog synthesizers. We also found a wide range of live versions of the song and we attempt to narrow down our choices of covers. 

*Listen to the pre-episode introduction for a special "get well soon" message from the TMBP listeners.* OG fan Stanley Allen makes his first appearance on the show to remind Greg of the greatness of Rowboat Mayor, another My Murdered Remains track. They discuss music of all types that informed their fandoms of TMBG and ponder young Flansburgh's own fandoms of punk and post punk bands that could have steered the rowboat of his tastes, even so much later on in life  when writing a song like this. We also hear two great custom covers, now also featured on the Covers by Order compilation to benefit the NAACP Legal Defense Fund. Go to our bandcamp to purchase and donate. This episode edited and mixed by Avren Keating of the Waves Breaking podcast. Thanks Avren!  

This week on TMBP we try a cold open where we just say nice things to each other, one Dan has a videogame meltdown, and both Dan's are put to the test by having to potentially admit that M. Night didn't completely f&*k something up.

Merry Christmas from TMBP! Joe of OK Glass joins us to talk about this unreleased fan favorite from deep in the Giants' secret vault. We talk about the many different possible influences on this weird sad Christmas number, managing to keep spirits both holly and jolly!

It's Horn Month here at TMBP and first up is frequent TMBG trombonist and multi-intrumentalist Dan Levine to talk about Electric Car off of Here Comes Science. Dan arranged the winds in this song, and there is a lot to discuss! Much band nerdery ensues.

Strap it in for the longest TMBP weekly episode to date! A double-dose episode with one of the weirdest of the weird stories in TMBG lore. My guest is professional opera singer Steve Pence, who has worked with John Williams. No kidding. Just give this monster a listen, it might take you a few days. Amazing covers, amazing revelations, and an amazing conversation.

Nearly two years ago, TMBP had our first live episode about Don't Let's Start. We don't do covers sections on a live episode, but there are so many great covers of this epic song! Two members of that roundtable rejoin me, Dana Williamson and Scott Currie, to find those great covers. Listen to some of TMBG's talented fans take on this tricky song in many different styles.

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I promised my amazing Patreon subscriber friends that when I reached a certain amount of subscriptions I would throw a PARTY via video call for all of us Patrons to shoot the breeze with each other about anything TMBG. On this 3rd party we've got Becca Ganey of Boston and two international Patreon subscribers, Coleman Hegarty of Ireland and Maciej Taubert of Poland. TMBP 'round the world, baby! Listen in to the VIPs as we talk about the success of TMBG at preserving a fanbase through generations and how they have attained one of the broadest age range of any rock bands' fanbase.

We all know TMBG have happy sounding songs about SAD things. But what TMBG songs are straight-up EMO? Tara Trate and Elizabeth Siegel join TMBP for the first time alongside the triumphant return of my wife Cara Kinnally to link TMBG to some of our favorite emo bands including Thursday, Elliott Smith, Bright Eyes, Front Bottoms and more. This is a simultaneously fun and SAD one...lol... so emo!

Greg appeared recently on Sadie Hawkins Pod to talk about Relient K's cover of Doctor Worm. To complete the crossover, here's Jess and Daniel Leary joining Greg on TMBP to talk about the early b-side For Science, a favorite of Daniel's. Strap it in folks, this is a long one with many funny tangents but a big payoff at the end... Let's get those missiles ready to destroy the pod-u-verse!

We’re doing cross-posting y’all! As the other half of the Giants Confirmed crossover, Trevor and Matt join Greg to talk about the Factory Showroom b-side, written for the Mighty Morphin’ Power Rangers movie soundtrack, and things get… nutty. Featuring an appearance by Greg’s baby, and a special twist ending!Check out TMBP on Twitter, Patreon and Apple Podcasts!

Giants Confirmed is an album-by-album They Might Be Giants podcast. Listen as Greg guests on their Factory Showroom episode, talking to hosts Matt Rebeiro and Trevor Ikrath about EVERY song on that album. This is a companion episode to the coming-in-twelve-hours episode of TMBP for Sensurround, a b-side to Factory Showroom, and a song on the Mighty Morphin Power Rangers movie soundtrack. Crossover tiiiime!

Greg was asked to be on the parenting podcast Parents Just Don't Understand when host Kurt Schiller found out about TMBP, figuring I knew a lot about TMBG's kids albums. I told him I did know them well, and also I'm an elementary music teacher! So we were off to the races and had a great evening talking about our childhood music, what our own kids are listening to, and what we think is good for kids to jam on from our point of view as parents. TMBG kids songs are the focus, so give it a listen, y'all!

Last Saturday, Greg and friends converged on Bloomington, IN, in the southern half of the state and home to Indiana University, to record our third live episode at The Bishop Bar. With a roundtable made up of TMBP newcomer and regional comedian extraordinaire Jon Hancuff alongside TMBP veterans Cari Hearn, Dana Williamson and Scott Currie, listen to Greg attempt to wrangle the rowdy crew as we discuss They'll Need A Crane in great detail with hysterical moments along the way. The episode ends with a live cover of the song, with only minimal mistakes. Awesome!

The 2019-2020 NBA season is two weeks away and we couldn't be more hyped! And since most of our fantasies revolve around basketball here at TMBP, we decided to follow that through to it's natural conclusion: FANTASY BASKETBALL! We've invited our friends Seth Adams, Julie Parr (tacet), and Justin Sechrist to join our league for this season. Check out our draft on this episode and be sure to tune in for regular updates throughout the season.

Virginia musician Matt Monta visits TMBP again to talk about Rabid Child. As you might expect with this song, things get weird.

It's still Polish Week here on TMBP and on this second episode with Warsaw's Maciej Taubert, we cover the new-ish TMBG song The Communists Have The Music. This song won the Twitter poll for most requested song for me to do an episode on, so it's jumped the queue just for you all! Now the question is... is Maciej a Commie? Listen to find out!

It's Polish Week here on TMBP! On this first episode with Warsaw's Maciej Taubert, we cover the classic Lincoln track I've Got a Match.

Mike Park, owner of Asian Man Records and member of Skankin Pickle, Ogikubo Station and more, drops by TMBP to talk about the first song on the first TMBG album, Everything Right Is Wrong Again. They delve into the song's multiple demos, listen to a couple covers and Mike even does his own cover live on the episode!

Even more content for y’all! I guested on an episode of Barenaked ABCs, the song-by-song Barenaked Ladies podcast, to talk about their song Daydreaming’. It’s a great podcast and a fun crew that welcomed me with open arms and we had a ball. They’ll be guesting on two later episode of TMBP as well to talk about the Giants! Enjoy, and find their full feed of episodes on iTunes and SoundCloud.

T cells directed against brain antigens are generally held to play a crucial role in the initiation of multiple sclerosis (MS). This was deduced from experimental autoimmune encephalomyelitis (EAE). In this model for MS, T cells reactive for myelin antigens induced a severe paralytic disease upon transfer to healthy syngeneic recipients. Intriguingly, the disease does not start immediately upon transfer of the pathogenic effector T cells. Instead, as earlier studies have shown, the effector T cells attack their target organ only after having migrated in the periphery through secondary lymphoid organs. The aim of the project was to characterize the functional properties of these migrating encephalitogenic T cells during the course of EAE and to identify biological pathways which determine their migratory behaviour and pathogenic potential. To this end, average linkage hierarchical clustering, pathway and gene ontology (GO) analyses of transcriptomes from cultured and ex vivo-isolated myelin basic protein-reactive T cells (TMBP cells) were performed. At the time of transfer, encephalitogenic T cells in vitro are maximally activated, i.e. they exhibit a prominent upregulation of cell cycle genes such as cyclin A2 (CCNA2) and cyclin B2 (CCNB2) among others. In contrast, T cells isolated from spleen 3 days post transfer, downregulated activation markers such as interleukin 2 receptor (IL2R) and interferon γ (IFNγ), and at the same time upregulated migration specific genes such as CC-chemokine receptor 1 (CCR1), CC-chemokine receptor 2 (CCR2) and CC-chemokine receptor 5 (CCR5). Hierarchical cluster analysis revealed that several transcription regulators known for inhibiting cell cycle progression such as krüppel-like factor 4 (KLF4), B-cell translocation gene 2 (BTG2) and transducer of ERBB2, 1 (TOB1) were clustered together with cell cycle and migration genes. Overexpression of KLF4 in T cells not only inhibited G1/S phase progression of the cell cycle but additionally induced upregulation of CCR2 and CCR5. A novel tetraspan membrane protein called epithelial membrane protein (EMP1), was found to be up regulated in ex vivo-isolated effector T cells. Overexpression of EMP1 in encephalitogenic T cells influenced the migratory behaviour of effector T cells both in vitro and in vivo. EMP1 enhanced T cell motility within the extracellular matrix milieu in vitro and promoted T cell migration from the connective tissue to lymph nodes in vivo resulting in an accelerated onset of EAE. In conclusion, gene expression profiling of encephalitogenic T cells revealed interesting genome wide transcriptomic changes and established a correlation between cell cycle progression and cell migration. As a result, in silico analysis put forth several interesting candidate genes that hold promise as potential targets for therapeutic intervention.