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Lihi Segal joined us for a conversation moderated by VillageMD Chief Marketing Officer Ellen Donahue-Dalton to discuss her experiences leading both startups and large public enterprises, the inspiration and motivation behind founding DayTwo and advice for fellow entrepreneurs.Lihi founded DayTwo in 2015 to bring personalized health solutions based on the gut microbiome into the mainstream consumer market. Since then, the company has become a leader in precision nutrition with the world's largest and highest resolution microbiome discovery platform, offering a sustainable path to remission for metabolic disease.DayTwo's results set a new national benchmark for diabetes and metabolic disease care, with significant sustained clinical results in reducing A1C, improving Time in Range and reducing or eliminating prescription medications. Their scientific research is cited by the NIH as a foundational element in its 10 year, $150 million strategic plan for precision nutrition.The Tales from the Trenches series invites seasoned healthcare entrepreneurs to the MATTER stage to share their journeys — from how they got started to what they're trying to accomplish and what they've learned along the way. Tales from the Trenches is sponsored by VillageMD.Register for the more MATTER events here.
In 2014, Aneesh Chopra co-founded CareJourney: a digital health startup that provides clinically-relevant analytics for value-based networks, ultimately enabling its clients to coordinate better outcomes for their patients. Prior to founding CareJourney, Aneesh served as the first chief technology officer of the United States. Appointed by President Barack Obama in 2009, Aneesh spent his three-year service promoting technological innovation, leading initiatives and implementing programs focused on entrepreneurship, healthcare and more. In 2014, Aneesh published Innovative State: How New Technologies Can Transform Government, which details his public service and the need for better collaboration between the public and private sectors.Aneesh joins us in a conversation moderated by VillageMD Chief Technology Officer Mike Roberts to discuss his decades-long career in both the public and private sectors and the lessons he has learned along the way.The Tales from the Trenches series invites seasoned healthcare entrepreneurs to the MATTER stage to share their journeys — from how they got started to what they're trying to accomplish and what they've learned along the way. Tales from the Trenches is sponsored by VillageMD.Register for the next event in our series, featuring Lihi Segal of DayTwo, here.
Interview with Lihi Segal, CEO and co-founder of DayTwoDayTwo provides personalized nutrition and actionable insights that allow you to live healthier and maintain normal blood sugar levels. 01:00 Lihi shares the story of the fouding of DayTwo03:46 Tell us a little bit about what we know about the gut microbiome, why you're using that, and a little bit about how that became the product that is DayTwo?08:15 How does one become a customer of DayTwo?10:00 What do you see as the benefits of having a real coach versus a digital one?14:00 What are the things that you are implementing currently in order to increase adherence?17:45 The DayTwo business model and difference between a healthy person and a Type2 diabetic person.20:15 What have you learned when analyzing the data from your customers?24:15 The clinical and scientific journey behind DayTwo's technology 28:50 How did the COVID pandemic affect DayTwo?31:10 What are your expansion plans globally?32:15 Are you looking at additional therapeutic areas beyond Diabetes?33:00 Tell us a bit about the investors of DayTwo37:35 How do you balance your personal life with the demands of being the CEO of DayTwo?
What if you could take a simple stool test that accurately predicted what you should eat to manage your blood sugar? The Day Two test does this, and provides you with a personalized diet plan to keep your blood sugar under control. In today’s podcast, I met with Lihi Segal from Day Two, to learn more about the test, and how it can help you with diabetes, weight loss, performance, and even IBS. https://drruscio.com/day-two My book Healthy Gut, Healthy You is available at https://drruscio.com/getgutbook/ Looking for more? Check out https://drruscio.com/resources
Description: What if the “right” thing isn’t the right thing for you? In Episode 21 of the Big Bold Health Podcast, Lihi Segal of DayTwo talks with Dr. Jeff Bland and James Maskell about how you can harness the link between your gut and glycemic control and why personalizing nutrition could be the key to unlocking your health potential! Show Notes: Want to learn more about DayTwo’s food as medicine blood sugar approach? Check it out here: www.daytwo.com
Lihi Segal explains how microbiomes are the key to health! I first heard about heard Lihi Segal in a TED Talk about how our diets are unique to our bodies. It was so interesting. It's not about how much we eat, it's the precise mix of foods we consume. I reached out to Lihi and DayTwo, her research company that's developing this new approach, to see if they would share with us their research findings and what it might mean for each of us. The implications of this new understanding of nutrition are enormous. What if we all could be healthier and avoid disease if we better understood what's good and bad for our individual bodies? This is big. Listen in, learn and share this conversation! It could change your life. Perhaps it is time to think about not A DIET but YOUR DIET Lihi Segal is CEO and co-founder of DayTwo, a leader in the development of microbiome-based precision medicine, focusing on metabolic disease. For those of us who don't know, your gut microbiome is the collection of all the microbes (around 100 trillion) that exist in your digestive tract and help you digest food. Your microbiome is unique to you, and influences the way your body reacts to different foods. A new frontier in medicine A study conducted in 2015 at the Weizmann Institute of Science in Israel and published in Cell was the catalyst that got Lihi into the field of personalized, microbiome-based diet solutions. The study, which for one week continuously monitored blood sugar levels in over a thousand people, revealed that the bodily response to foods was highly individual. Called the Personalized Nutrition Project, the study was led by Professors Eran Segal of the Computer Science and Applied Mathematics Department and Eran Elinav of the Immunology Department. They decided to look at why diets fail and why one person can eat, say, bread and another person can't. Segal and Elinav decided that perhaps the whole approach is wrong and instead of looking at the food, we need to look at the person. This led them to develop an algorithm that collects a person's health data and then predicts which foods and meals would be good for them and which would be bad, with "good" being a meal that doesn't spike blood sugar levels after eating it. Prof. Segal said: “We chose to focus on blood sugar because elevated levels are a major risk factor for diabetes, obesity and metabolic syndrome. The huge differences in the rise of blood sugar levels among different people who consumed identical meals highlights why personalized eating choices are more likely than universal dietary advice to help people stay healthy.” It's all about your gut microbiome What caught Lihi's attention was the ability of Segal and Elinav's technology to customize low blood sugar level diets for each individual, something very new in the nutrition realm, so her company licensed it. If she could help people avoid disease, and death, Lihi was in. Researchers at DayTwo then built a mathematical predictive model app that tells you how your blood sugar is going to respond to any meal you eat. Based on that model, they now can create customized diets for their clients so they can successfully avoid high blood sugar levels that cause energy dips, excessive hunger, weight gain and increased risk of obesity and diabetes. As part of their program, they also provide suggested meals, snacks and the services of a dietician. Along these same lines, recent research has shown that your genetic background is not as influential in your microbiome as you might have thought. It is less genetics than a reflection of the people you live with, the foods, drugs and drinks you consume, and your lifestyle. That's why DayTwo's assessment methodology is so innovative—it helps you identify the right diet for your personal “gut.” Think about the implications of this approach Your health to a very large extent stems from how your body processes food. The trillions of bacteria that live in your gut, which differ greatly from person to person, are part of how you uniquely respond to food. Different people have different blood sugar responses to the same foods, which is why it is essential to understand what your particular body needs—and to eat accordingly. Wanting to bring this groundbreaking technology from Isreal to the U.S., Lihi and DayTwo helped the Mayo Clinic replicate the Weizmann Institute trial which got the same results. Heidi Nelson, M.D., director of the Mayo Clinic Center for Individualized Medicine Microbiome Program, explains: “We have long wondered why one diet works for one person, but not another. Now, we are beginning to understand that how a person processes food depends upon that individual’s gut microbiome, immune system and the community of bacteria in the gut. Given these multiple factors, we are exploring ways to develop customized diets that will maintain wellness and prevent the development of disease." Nelson adds: "Glucose levels are abnormally high in patients with diabetes, and traditional interventions to control glucose levels have had limited benefit for them. These study results highlight the important role that personalized diets can play in maintaining better control over blood glucose levels and overall health." How do you get started with DayTwo? As Lihi tells us in the podcast, just go to DayTwo's website and order your home testing kit online, which contains everything you need. In addition, over 200 clinics in the U.S. have signed up with her program. Better health is actually attainable for all of us. Some background on Lihi Lihi Segal has over 20 years of experience leading business and financial operations, spanning Interoperability and Health Information Exchange (HIE), Population Management, Electronic Health Records and Analytics. Before launching DayTwo, Lihi was COO and CFO of Sisense, a leading provider of business intelligence and analytics software, and CFO of dbMotion Ltd. where she was instrumental in growing the company up until its acquisition by Allscripts Healthcare, a leading U.S. EMR company. Prior to that, Lihi held senior roles in a number of businesses, from startups to large public enterprises. She is also a lawyer with an LLB from Tel-Aviv University and an MBA from Northwestern University. Additional resources: DayTwo website Watch a demo of the DayTwo app My book: "On the Brink: A Fresh Lens to Take Your Business to New Heights" Our website: Simon Associates Management Consultants Download the 1-page synopsis of my book, "On the Brink: A Fresh Lens to Take Your Business to New Heights" here
In this episode, we’re diving into the research, and a brand new solution, focused on the growing understanding of the human microbiome – the microorganisms that help protect us against germs, break down food, and produce vitamins. We discuss the work that is being done to enlist the microbiome in the fight against disease, and how we can leverage our understanding not just to preserve health but also to actually prevent or treat metabolic disease. Our guest is Lihi Segal, co-founder of Day Two. Day Two was started in 2015 to bring personalized health solutions based on the gut microbiome into the consumer mainstream. [...read more...] Get the full show notes here. --- This episode of Digital Health Today is made possible thanks to our sponsors. Thank you! --- Learn more about your ad choices. Visit megaphone.fm/adchoices
Lihi Segal is the CEO and co-founder of revolutionary microbiome-based health app, DayTwo, which uses big data and machine learning algorithms to create personalised nutrition plans. DayTwo is based on research conducted by Professor Eran Segal and Eran Elinav from the Weizmann Institute in Israel, which was used to create an algorithm that can predict a patient’s glucose response to foods based on their personal and microbiome data. The algorithm was shown to accurately predict blood glucose responses in 800 participants whose individual blood glucose was highly variable in response to the same meal. Since 2016, DayTwo has offered their accessible and personalised healthcare services throughout Israel and the United States, delivering evidence-based and personalised healthcare to consumers.
Lihi Segal is the CEO and co-founder of revolutionary microbiome-based health app, DayTwo, which uses big data and machine learning algorithms to create personalised nutrition plans. DayTwo is based on research conducted by Professor Eran Segal and Eran Elinav from the Weizmann Institute in Israel, which was used to create an algorithm that can predict a patient’s glucose response to foods based on their personal and microbiome data. The algorithm was shown to accurately predict blood glucose responses in 800 participants whose individual blood glucose was highly variable in response to the same meal. Since 2016, DayTwo has offered their accessible and personalised healthcare services throughout Israel and the United States, delivering evidence-based and personalised healthcare to consumers.
1. “Neither Hamas Nor Hezbollah Currently Pose Major Threats” The Chief-Of-Staff of the Israel Army Gadi Eisenkot conveyed to the Foreign Affairs and Defense Committee that neither Hamas nor Hezbollah pose major threat to the security of Israel. #Eisenkot #Hamas #Hezbollah ____________________ 2. Jewish Community Centers Targeted 69 Times Since Jan. 2017 In response to the latest wave of bomb threats leveled against Jewish community centers and institutions around the US, over 150 Congress men and women signed a letter calling for a sense of urgency in investigating the matter. #BombThreats #Jewry ____________________ 3. Major Jewish Organization Oppose Trump Policy On Refugees Hartman Institute Intellectual Yossi Klein Halevy told ILTV's Steve Lebowitz that the entire American Jewish community opposes the controversial Trump administration policies that restrict the entry of refugees and that American Jewry should be pleased that Trump has been fulfilling his campaign promises regarding the U.N. and Iran. #YossiKlein #Trump #SteveLeibowitz ____________________ 4. U.N. Voices Concern Over Israeli West Bank Demolition Plans The United Nations voices concern over the new announcement that several buildings in a West Bank Bedouin village near Jerusalem are going to be demolished. #UN #WestBank #Demolition ____________________ 5. Iron Dome Reportedly Gets An Upgrade The Israeli Iron Dome missile defense system has reportedly been given an upgrade. According to the Defense Ministry, the system passed all new tests. #IronDome #DefenseMinistry ____________________ 6. Netanyahu Continues Meetings With Australian Leaders Israeli Prime Minister Benjamin Netanyahu is continuing his meetings with leaders in Australia today in talks primarily focused on bolstering bilateral trade. #Netanyahu #Australia ____________________ 7. Israeli Minister Makes Impromptu Bid For ‘Siloam Inscription' Israeli Culture And Sport Minister Miri Regev offered two elephants to Turkey in exchange for a precious artifact "Siloam Inscription" that was removed by the Ottoman Empire. #MiriRegev #Turkey #Elephants ____________________ 8. What's Your Personalized Pro-Gut-Microbiome Diet? Lihi Segal, CEO & Co-Founder of DayTwo speaking at ILTV studio about Israeli company DayTwo that has created a novel way to boost the body's ability to treat itself. #LihiSegal #DayTwo ____________________ 9. Gaza's ‘Capital Mall' Opens; Attracts Crowds Of Curious Locals A new mall has opened in Gaza City but the long term outcome of shopping center uncertain amid poor economy. #Mall #Gaza ____________________ 10. Jerusalem Virtual Tour Takes Visitors Back 2,000 Years The “Western Wall Heritage Foundation” will now offer a 360-degree virtual tour taking the visitors back 2000 years based on comprehensive historic, archeological and religious research. #Jerusalem #Tour ____________________ 11. Hebrew Word Of The Day, TAYAR | תייר = TOURIST Learn a new Hebrew word every day. Today's word is "tayar" which means "tourist" #Learnhebrew #Hebrewwordofday #Iltvhebrewwordofday _____________________ 12. The Weather Forecast Tonight should be clear to partly cloudy with a low of forty-eight; or nine degrees Celsius. The temperatures are set to rise over the weekend as the high floats at around 70, or twenty-one degrees Celsius. #Israelweather #Israelforecast See omnystudio.com/listener for privacy information.
Is your glucose metabolism driven by your personal microbiome? Recent research reveals how the microbiome influences blood glucose, weight gain and weight loss. And how the new company, "Day Two", is using microbiome sequencing data to provide personalized nutrition recommendations. In this episode we discuss how personal your blood glucose response and regulation is. We look at how glucose metabolism can differ from one person to another, and how it differs based on typical measures, such as the hypoglycemic index. Most research studies try to understand what a diet or food does to an average person. But the question is whether ...