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Shaun will NOT bow down to the Democrats demands! PLUS, Dr. Nick and Leah Wilson, authors of the upcoming book Reclaim Vitality: A Guide to Exit Conventional Medicine and Live Naturally, tells Shaun about the whole genome sequencing program the NIH is rolling out to collect every baby's entire genome sequence, funneling kids into biotech therapies, and their fight to shape public health policies so people can stand for their own health freedoms. And The Heritage Foundation's Dr. EJ Antoni discusses the possible implications of BlackRock owning both the meat packing and pharmaceutical industries, Obamacare subsidies, and Trump's meeting with NYC mayor-elect Zohran Mamdani. See omnystudio.com/listener for privacy information.
Send us a textA vaccine built for a virus might be whispering a powerful message to cancer care. We dig into a new Nature paper suggesting that mRNA COVID shots could enhance the effectiveness of checkpoint inhibitor immunotherapy—especially in non‑small cell lung cancer and melanoma—by acting as an immune alarm that sharpens anti‑tumor responses. The data is retrospective, not causal, so we break down why the signal is exciting, where confounders can hide, and what the next generation of trials must test: timing, vaccine type, biomarkers, and who stands to benefit most.From there, we switch gears to the first weeks of a dog's life. A small but detailed study of Australian breeders maps nine practical socialization steps—novel objects, varied surfaces, calibrated sound exposure, hands‑on handling, human visitors, other animals, off‑site trips, car rides, and rotating environments—that build confident, adaptable companions. We compare three rearing strategies, from uniform protocols to individual puppy plans, and connect these choices to fewer fear issues, better training outcomes, and smoother vet and grooming visits down the line.Journalist and author Melanie Kaplan joins us to share Hammy's story—a beagle rescued from a research lab—and the deeper reporting behind her book, Lab Dog: A Beagle and His Human Investigate the Surprising World of Animal Research. We talk about why beagles became the default lab dog, the emotional toll and resilience of retired animals, and the promising rise of non‑animal alternatives like organs‑on‑chips, human cell models, and computational toxicology. With FDA and NIH signaling support for methods that are more humane and more predictive, there's a real path to better science with less harm.If this conversation moved you or made you think, follow the show, share it with a friend who loves science and animals, and leave a quick review to help others find us.Links to Melanie's Book and SocialsHere is the link to all our socials and stuff!!!Support the showFor Science, Empathy, and Cuteness!Being Kind is a Superpower. All our social links are here!
Full Show Notes: https://bengreenfieldlife.com/drandrew Dr. Andrew Koutnik is a research scientist whose career bridges cutting-edge science, elite performance, and personal experience living with type 1 diabetes for over 17 years. His work focuses on how nutrition, metabolism, and lifestyle can be leveraged to maximize human health, performance, and resilience across diverse conditions—from chronic disease to extreme environments. Dr. Andrew Koutnik earned his Ph.D. in Medical Sciences (Molecular Pharmacology and Physiology) from the University of South Florida Morsani College of Medicine. Prior to joining FSU, Dr. Andrew Koutnik served as a Faculty/Principal Investigator at Sansum Diabetes Research Institute and Florida Institute for Human and Machine Cognition. His research has spanned over $70,000,000 in research funding, including NASA missions, U.S. Special Operations Command, Defense Advanced Research Projects, Office of Naval Research, Department of Defense, and NIH-funded clinical trials Episode Sponsors: LVLUP Health: I trust and recommend LVLUP Health for your peptide needs as they third-party test every single batch of their peptides to ensure you’re getting exactly what you pay for and the results you’re after! Head over to lvluphealth.com/BGL and use code BEN15 for a special discount on their game-changing range of products. Ketone-IQ: Ketones are a uniquely powerful macronutrient that can cross the blood-brain barrier and increase brain energy and efficiency. With a daily dose of Ketone-IQ, you'll notice a radical boost in focus, endurance, and performance. Save 30% off your first subscription order of Ketone-IQ at Ketone.com/BENG. CAROL Bike: The science is clear—CAROL Bike is your ticket to a healthier, more vibrant life. And for a limited time, you can get $100 off yours with the code BEN. Don't wait any longer, join over 25,000 riders and visit carolbike.com/ben today. Sunlighten: Sunlighten's patented infrared sauna technology delivers the highest quality near, mid, and far infrared wavelengths to reduce inflammation, boost mitochondrial function, enhance detox pathways, and optimize recovery—backed by 25+ years of clinically proven, non-toxic innovation. Save up to $1,400 at Sunlighten.com/BEN with code BEN. Gameday Men’s Health: Gameday Men's Health offers science-backed, physician-led men's health optimization with personalized protocols for testosterone, peptide therapy, ED treatment, and more—helping you perform at your best whether you're training hard or keeping up with life. Visit gamedaymenshealth.com/bengreenfield for a free testosterone test and consultation at a clinic near you. Boundless Bar: If you’re ready to fuel workouts, sharpen your focus, and support whole-body vitality, grab your Boundless Bars now at boundlessbar.com —and save 10% when you sign up for a Boundless Bar subscription.See omnystudio.com/listener for privacy information.
Dr. Rachel Gatlin entered neuroscience with curiosity and optimism. Then came chaos. She started her PhD at the University of Utah in March 2020—right as the world shut down. Her lab barely existed. Her advisor was on leave. Her project focused on isolation stress in mice, and then every human on earth became her control group. Rachel fought through supply shortages, grant freezes, and the brutal postdoc job market that treats scientists like disposable parts. When her first offer vanished under a hiring freeze, she doubled down, rewrote her plan, and won her own NIH training grant. Her story is about survival in the most literal sense—how to keep your brain intact when the system built to train you keeps collapsing.RELATED LINKS• Dr. Rachel Gatlin on LinkedIn• Dr. Gatlin's Paper Preprint• Dr. Eric Nestler on Wikipedia• News Coverage: Class of 2025 – PhD Students Redefine PrioritiesFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship email podcasts@matthewzachary.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
When David Fajgenbaum nearly died of Castleman disease for the fifth time, he decided to take fate into his own hands. Using his medical training, he searched for an existing drug that might save his life—and found one. Now his organization, Every Cure, is scaling the same approach to uncover hidden treatments for other diseases with no known cure. David and Claudia discussed: How Every Cure is using AI to test 75 million possible disease-drug combinations The perverse incentives that keep generic drug repurposing in the shadowsWhy the hardest part of innovation isn't discovery, it's getting proven treatments into clinical practiceRepurposing existing drugs makes so much sense. But as David points out, there's no market for it:“Once a drug is generic.. the price is going to plummet… And even if you were to double the sales of your drug because you found a new disease area, now you've gone from 1% to 2% of what you got before… So there's no incentive whatsoever for our system to find a new use for a generic drug. Zero incentive.”Relevant LinksLearn more about Every CureRead David's book Chasing My Cure: A Doctor's Race to Turn Hope Into ActionWatch David's TEDTalk Listen to David's Podcast interview with Adam GrantGet info on the Dada2 FoundationWatch a video on Matt Might's story About Our GuestDavid Fajgenbaum, MD, MBA, MSc, is co-Founder & President of Every Cure and a physician-scientist at the University of Pennsylvania, where he is one of the youngest faculty members ever to receive tenure at Penn Medicine. He is also the national bestselling author of Chasing My Cure: A Doctor's Race to Turn Hope Into Action, which is being adapted into a film by Forrest Gump producer Wendy Finerman. During medical school, Fajgenbaum discovered a treatment that saved his own life and founded the Castleman Disease Collaborative Network. He has advanced 13 more repurposed treatments for cancers and rare diseases and co-founded Every Cure to unlock more hidden cures from existing medicines which has received over $100M from ARPA-H and TED's Audacious Project. He also serves on the Board of Directors for the Reagan-Udall Foundation for the FDA. One of the youngest recipients of multiple top NIH and FDA grants, Fajgenbaum has authored over 100 scientific papers in leading journals, including The New England Journal of...
Cancer is a disease caused by the uncontrolled growth of cells that escape the body's natural defenses. One way cancer protects itself is by taking advantage of certain immune cells called regulatory T cells, or Tregs. Normally, Tregs help prevent autoimmune diseases by controlling the immune system. But inside tumors, they behave differently. Instead of defending the body, they suppress the immune cells that could attack the cancer. Many cancer treatments aim to activate the immune system to fight tumors more effectively. However, the presence of Tregs within the tumor makes this difficult. These cells act like bodyguards for the cancer, blocking the immune response that might otherwise slow or stop tumor growth. Researchers have tried to eliminate Tregs by targeting a protein called CD25, found on their surface. However, earlier efforts often failed because these treatments also interfere with interleukin-2 (IL-2), a molecule that is essential for other immune cells to function. Blocking IL-2 weakens the entire immune response, limiting the treatment's effectiveness. To overcome this challenge, scientists recently developed a new antibody called 2B010. This study, titled “A novel anti-human CD25 mAb with preferential reactivity to activated T regulatory cells depletes them from the tumor microenvironment,” was published in Oncotarget (Volume 16). Full blog - https://www.oncotarget.org/2025/11/19/new-antibody-removes-tregs-to-boost-immune-response-against-cancer/ Paper DOI - https://doi.org/10.18632/oncotarget.28752 Correspondence to - Ethan M. Shevach - eshevach@Niaid.NIH.gov Abstract video - https://www.youtube.com/watch?v=2NJcGsI7WXA Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28752 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, Treg, CD25, TME, mAb, GVHD To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM
The city Finance Committee voted down Mayor Johnson's revenue plan, dealing a significant blow to his 2026 budget. Crain's politics reporter Justin Laurence discusses with host Amy Guth.Plus: Hines eyes Boeing's West Loop tower after scuttled Sterling Bay deal, Big Ten's $2.4 billion deal talks extended after pushback, FTC drops fight for injunction blocking GTCR's Surmodics deal and a study finds NIH grant cuts leave hundreds of clinical trials, 74,000 patients in limbo. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Prenatal substance use is often misunderstood, oversimplified, and met with stigma instead of support. In this conversation, Christina Dent and Meghann Perry explore the complex realities facing mothers who use substances during pregnancy—from trauma and addiction to healthcare barriers and the fear of criminalization. Together, they reflect on the importance of compassionate care, the power of bonding and attachment, and what it looks like to invest in families so both moms and babies can thrive. This episode invites us to move beyond judgment and toward curiosity, connection, and systems that heal rather than harm. About Meghann: Meghann Perry, CARC, RCPF, is an award-winning keynote speaker, storyteller, theatre educator, curriculum developer, harm reductionist and addiction recovery coach. She creates innovative learning experiences blending Theatre, Storytelling, and Coaching and is an international educator of the behavioral health workforce. Meghann is the author of two groundbreaking programs, Recovery Storytelling and Embodied Storytelling, and a global keynote speaker and presenter on peer support, storytelling, and stigma for organizations like NIH, NAADAC, FAVOR, PRCoE, HRSA, Hazelden, and the recent Lisbon Addictions Conference. Meghann is a person who used drugs who passionately supports people in prevention, harm reduction and recovery and leads a team of dedicated facilitators redefining education and intervention in the substance and mental health field. Links: Meghann's paper in Health Affairs: www.healthaffairs.org/doi/10.1377/hlthaff.2025.00647 Meghann Perry Group website: www.meghannperry.com Keywords: prenatal substance use, maternal health, addiction, recovery, healthcare, bonding, criminalization, compassionate care, systemic issues, early childhood trauma.
Medsider Radio: Learn from Medical Device and Medtech Thought Leaders
In this episode of Medsider Radio, we sat down with Kaitlin Maier, co-founder and CEO of Reia. Reia has developed a self-managed pessary — a collapsible device that empowers women to treat pelvic organ prolapse comfortably and independently. A mechanical engineering graduate of Dartmouth, Kaitlin previously worked at Sherpa Technology Group, developing patent strategies for leading life science and technology firms. In this conversation, Kaitlin shares how she and her co-founders turned a student project into an FDA-cleared product using resource constraints as a design advantage. She explains how to turn FDA feedback into forward momentum, why running an NIH-funded randomized controlled trial (RCT) strengthened both credibility and confidence, and how non-dilutive funding can buy the time and control founders need to build on their own terms.Before we dive into the discussion, I wanted to mention a few things:First, if you're into learning from medical device and health technology founders and CEOs, and want to know when new interviews are live, head over to Medsider.com and sign up for our free newsletter.Second, if you want to peek behind the curtain of the world's most successful startups, you should consider a Medsider premium membership. You'll learn the strategies and tactics that founders and CEOs use to build and grow companies like Silk Road Medical, AliveCor, Shockwave Medical, and hundreds more!We recently introduced some fantastic additions exclusively for Medsider premium members, including playbooks, which are curated collections of our top Medsider interviews on key topics like capital fundraising and risk mitigation, and 3 packages that will help you make use of our database of 750+ life science investors more efficiently for your fundraise and help you discover your next medical device or health technology investor!In addition to the entire back catalog of Medsider interviews over the past decade, premium members also get a copy of every volume of Medsider Mentors at no additional cost, including the latest Medsider Mentors Volume VII. If you're interested, go to medsider.com/subscribe to learn more.Lastly, if you'd rather read than listen, here's a link to the full interview with Kaitlin Maier.
storically tumultuous year for federal employees didn't dim the public's pre-shutdown view of government services, according to a new survey that largely credited tech adoption for the positive perceptions. The 2025 American Customer Satisfaction Index Federal Government Study, released Tuesday, found citizen satisfaction with federal government services at a 19-year high with a score of 70.4 on a 0-to-100 scale, a 1% jump from 2024. The survey of 6,914 randomly chosen respondents was conducted before the longest government shutdown in U.S. history, but ACSI's director of research emeritus emphasized that the results still “reflect real momentum in improving how citizens experience federal services.” Forrest Morgeson, an associate professor of marketing at Michigan State in addition to his role at ACSI, said that the introduction of AI is making a large impact, and such advancement “signal a future where government services can be more responsive and accessible to all.” Many of the highest-ranking federal agencies in customer satisfaction were lauded for their implementation of technologies, including USDA, the State Department and the Small Business Administration. The National Institutes of Health didn't ensure that the entity housing personal health information of over 1 million people — including biosamples — implemented proper cybersecurity protocols, according to an internal watchdog. In a report publicly released Friday, the Department of Health and Human Services' Office of Inspector General made five recommendations for the security of the All of Us program — a database of diverse health information from 1 million participants that's meant to aid research — after finding weaknesses. According to the report, while the award recipient operating the program's Data and Research Center implemented some cybersecurity measures, NIH failed to ensure other controls were addressed. The report found that NIH didn't ensure that the awardee, which wasn't identified, appropriately limited access to the program's data and didn't communicate national security concerns related to maintaining genomic data — or data relating to DNA. It also failed to ensure that weaknesses in security and privacy were fixed within a timeline outlined in federal requirements. The audit was initially conducted by the inspector general due to the threats that cyberattacks and the potential exposure of sensitive information can pose to the agency's programs. The watchdog's objective was to scrutinize the access, security and privacy controls of the program. Also in this episode: HPE Networking Chief AI Officer Bob Friday joins SNG host Wyatt Kash in a sponsored podcast discussion on how agencies can leverage cloud and AI to build more automated, secure and mission-ready networks. This segment was sponsored by HPE.
Who is MD Gov Moore targeting with his new political slate? The legality of creating an 8-0 Democratic advantage in the Congressional District map in Maryland. Regional grid operator members vote on new rules for adding. Half of NIH institutes have short two-week director searches open. And more. Music by Kara Levchenko.
A new JAMA Internal Medicine study reveals that Trump's NIH funding cuts have abruptly halted nearly 400 clinical trials, leaving more than 74,000 patients — especially those in underserved communities — without essential care and research options. Subscribe to our newsletter to stay informed with the latest news from a leading Black-owned & controlled media company: https://aurn.com/newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
In this on-site conversation from the AAO-HNSF 2025 Annual Meeting & OTO EXPO in Indianapolis, host Rahul K. Shah, MD, MBA, AAO-HNS/F EVP and CEO, sits down with Gregory J. Basura, MD, PhD, Chair of the AAO-HNSF Humanitarian Efforts Committee. They explore the intersection of neuroscience, clinical innovation, and global humanitarian outreach—from Dr. Basura's NIH-funded research in tinnitus neuroimaging to his transformative fellowship and capacity-building work across Africa and beyond. Listeners will hear how early mentorship inspired his lifelong commitment to global otolaryngology, how partnerships in Ghana and Cape Town evolved into the creation of the African Otological Society, and how this collaborative model is now expanding into South America. The episode is both a scientific deep-dive and a call to service, highlighting the power of sustainable global training and mentorship in our specialty
BrainStorm wants to hear from you! Send us a text.The quest to speed up clinical trials is personal for John Dwyer, CEO of the Global Alzheimer's Platform (GAP). A long-time UsA2 advocate, he's been motivated by the generations of family members lost to Alzheimer's and Parkinson's disease. Dwyer shares with BrainStorm host Meryl Comer the critical challenges of NIH funding cuts by the Trump Administration, forcing many trial sites to shut down at a time of new FDA-cleared blood tests for early diagnosis. Dwyer highlights GAP's innovations in improving the participant experience through streamlining visits, personalized feedback, and bringing mobile trials directly to small communities. This must listen episode reinforces clinical trial participation as a valuable care option while advancing research for millions affected by Alzheimer's and related dementias. This episode of BrainStorm is sponsored by Johnson & JohnsonSupport the show
Send us a textGood morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world. Today, we delve into a host of transformative events reshaping the landscape, from strategic acquisitions and funding infusions to regulatory maneuvers and scientific breakthroughs.Johnson & Johnson has taken a decisive step in its oncology strategy with the $3 billion acquisition of Halda's cell death technology. This acquisition, focusing on the "hold and kill" bifunctional small molecule platform, is poised to enhance J&J's prostate cancer pipeline significantly. It underscores J&J's commitment to expanding its oncology portfolio through innovative platforms designed to improve therapeutic outcomes. The move highlights a broader industry trend toward personalized medicine and targeted cancer therapies, which are becoming pivotal in improving patient care.In another domain of cancer treatment, Nuvalent has unveiled promising Phase 1/2 data for its candidate neladalkib, which could position the company as a formidable competitor to Pfizer's established lung cancer drug, Lorbrena. The promising data might expedite regulatory discussions with the FDA, potentially leading to an accelerated approval process. This development illustrates the competitive landscape in oncology, where firms strive to introduce novel therapies with improved efficacy and safety profiles.The field of antibody-drug conjugates (ADCs) is also experiencing significant advancements. A San Diego-based biotech has secured $120 million in funding to develop a best-in-class ADC formula, with support from Merck & Co. This initiative aims to refine the precision and efficacy of ADCs by delivering cytotoxic agents directly to cancer cells while minimizing collateral damage to healthy tissues. Such innovations are crucial as they represent a new frontier in targeted cancer therapy.In terms of financial activities, Artios Pharma's successful $115 million Series D funding round is set to bolster its clinical efforts in exploring DNA damage response inhibitors for cancer treatment. These inhibitors target cancer cells' ability to repair DNA damage, holding potential for more effective therapies against resistant cancer types. Meanwhile, Sofinnova Partners' €650 million raise for biotech and medtech investments amid a volatile economic environment underscores continued investor confidence in life sciences despite market uncertainties.Bayer is making strategic moves in China by opening an incubator in Beijing. This facility will host local biopharma companies such as Suzhou Puhe Biopharma and Beijing Youngen Technology, fostering innovation and collaboration within China's burgeoning biotech landscape. Such initiatives reflect global efforts to leverage regional strengths and foster cross-border collaborations.On the operational side, Nxera Pharma is restructuring its workforce by laying off 15% of its staff as part of a strategic pivot towards profitability. This decision mirrors broader industry trends where companies refocus resources on core projects to streamline operations and enhance financial stability.A recent study has highlighted the impact of NIH grant cuts on clinical trials across the United States. Over 383 trials involving more than 74,000 patients have been disrupted due to funding terminations under the current administration. This situation raises concerns about the sustainability of clinical research funding and its implications for ongoing medical advancements.Jazz Pharmaceuticals has reported practice-changing Phase 3 results for its HER2-targeted drug Ziihera for gastroesophageal adenocarcinoma. These findings reaffirm Jazz's confidence in positioning Ziihera as a preferred first-line treatment option for HER2-positive cancers, poSupport the show
Bare sju prosent av topptrenerne i norsk idrett er kvinner. Hva skyldes det, hvilke utfordringer møter kvinnelige topptrenere – og hva må til for å få flere kvinner inn i trenerrollen? Du møter Julia Mehre Ystgaard, som gikk rett fra master på NIH til å bli hovedtrener for Canadas langrennslandslag som hun jakter OL-medaljer til vinteren med. Hun er gjest sammen med Marte Bentzen, som har forska på dette ved Institutt for idrett og samfunnsvitenskap ved NIH. Forskeren foreslår tiltak som kan gjøre treneryrket til et mer bærekraftig yrke med bedre balanse mellom jobb og fritid– som også flere yngre mannlige trenere etterlyser. Samtalen handler om hvordan det er å være ung kvinnelig trener på toppnivå, om motstand, forventninger og likestilling – men også om drivkraft, mestring og håp for framtiden. Programledere: Christina Gjestvang og Gjermund Erikstein-Midtbø Redigering: Egilie Jafer Ali
What happens when a powerhouse research enterprise, a statewide health system, and a relentless push for access all meet at the same table? Our conversation with Dr. David Miller, CEO of Michigan Medicine, opens the door to a candid look at how precision care, digital tools, and financial reality collide—and how smart leadership turns that collision into progress.We dig into the new map of Michigan Medicine: the academic medical center in Ann Arbor, integrated hospitals in Lansing and West Michigan, and partnerships that extend specialty expertise across the state. Then we follow the research-to-care pipeline, from NIH-backed labs to clinical trials to real-world therapies. You'll hear how next-generation sequencing is making targeted cancer treatments more accessible, and why histotripsy—a noninvasive, ultrasound-based approach to treating liver tumors—is a model for bringing breakthroughs from engineering benches to exam rooms.Technology is more than a buzzword here. Dr. Miller explains how generative AI is cutting documentation time with ambient notes, speeding routine approvals, and supporting clinical decisions, all while keeping a human in the loop. We talk training the next wave of physicians to be technology fluent, and how virtual visits and remote monitoring expand access without trading away empathy. On payment and policy, we confront the hard parts: Medicaid churn, prior authorization friction, and the need for value-based insurance design that lowers barriers to high-value care. The throughline is simple and urgent—make it easier for patients to get the right care at the right time, and align incentives so innovation actually reaches people.If you care about healthcare that is precise, humane, and actually reachable, this conversation will give you a practical, hopeful blueprint. Subscribe, share with a friend who's navigating care, and leave a review to help more listeners find the show. Your feedback keeps this community sharp—and pushes the system toward what works.Support the showEngage the conversation on Substack at The Common Bridge!
The NIH has cut billions of dollars in research projects under the Trump administration. The AP's Jennifer King reports.
Piše Andraž Stevanovski, bereta Aleksander Golja in Eva Longyka Marušič. Nika Prusnik Kardum se v zbirki Ob reki mmmm bliža tistemu, kar so v teoriji jezika iskali poststrukturalisti – odprtosti pomena in gibljivosti subjekta. V njeni liriki je ta dinamični subjekt izjavljanja močno prisoten. Julia Kristeva je v Revoluciji pesniškega jezika opredelila subjekt v procesu, na točki, ko se iz razpoke rojeva pomen, ki hkrati razpada in se vzpostavlja. S predjezikovnim – z impulzi, zvočnostjo, ritmi in afekti, ki se pojavijo pred artikuliranim govorom – pesnica seka tisto, kar je Lacan označil za simbolno, in odpira prostor, kjer pomen še ni vklenjen v besedo. To zaznavajo tudi avtorji spremnih besed: Miklavž Komelj piše, da se »zbirka glasi«, saj da »pravi nosilec teh verzov ni papir, ampak glas, njen magični glas, ki prihaja tako globoko iz telesa«. Milan Dekleva je spremno besedo naslovil Liturgija dihanja v divjini sveta, Boris A. Novak pa piše, da »je bilo [ob uglasbitvi pesmi] mogoče slišati vsak zven in pomen, besedo, zlog,« ter nadaljuje: »in vsi smo čutili, da posluša tudi Prva Duša, skriti Bog …« Zbirko Ob reki mmmm sestavlja sedemnajst pesmi. V njih je veliko medmetov in glasov – v pesmi Sinjebradec sta to denimo dve kitici A-jev. Zbirka se odpira skozi mistiko in ezoteriko, kar najlepše prikaže mantrično ponavljanje v pesmi Zora/Volkovi: »Volkovi, volkovi, / tečem z volkovi. / Volkovi, volkovi, sanjam z volkovi. / Volkovi, volkovi, / plešem z volkovi. / Volkovi, volkovi / igram se z volkovi. / Volkovi, volkovi, / novi rodovi. / Volkovi, volkovi./ čas je za – auuuuuuu.« Zbirka je močno povezana z Naravo: v njej se pojavljajo sintagme, kot so »pradavna moč«, »pradavno srce«, »z naravo smo vsi sestre in brati«, v pesmi Zimska pa se lirska subjektinja z Naravo popolnoma izenači: »Nimam veliko, imam pa vse. / Vsa polja so moja, reke in gozdovi, / puščave in morja, zasneženi vrhovi.« Čeprav je naravna govorica ena izmed najbolj avtentičnih potez zbirke, se mestoma ponavlja v podobnih vzorcih, kar rahlo oslabi učinek presenečenja. Vzpostavi tudi odnos z Bogom, vendar v čezteološkem smislu. V pesmi Biblijo berem pride do sklepa, s katerim povzame duhovno jedro zbirke: »Bog ni ideja, Bog je občutek, odnos.« To povezavo – med mistiko, vero in naravo – lahko razume le nekdo, ki je z naravo povezan in je hkrati Narava sama. Tega svojega položaja večnosti in naravne pravilnosti se lirska subjektinja zaveda; v pesmi Molitev k temi pravi: »grem, kadar bi morala ostati, in ostanem, kadar bi morala iti.« Kljub izenačenju z Naravo in odnosu, ko je z Bogom že kar na ti, v lirski subjektinji ni napuha, temveč ponižnost. V pesmi Molitev domov pravi: »Ponižna sem pred tvojo veličino, / ponižna sem pred nevidnim / micelijem, ki ga ustvarjaš.« A kako ne bi bila ponižna, če se je, kot piše v uvodni pesmi, z umiranjem že rokovala. S tem pooseblja zavest o minljivosti, ki jo sodobni kapitalistični svet pogosto izgublja. Le Narava lahko ne glede na vse ostaja prvinska, svoja. V pesmi Zora/Volkovi se tega zaveda in pravi: »Hoteli so me pridobiti, / spreminjati, vzgojiti. / Ne, ni šlo, ni šlo, ni šlo, ni šlo.« Nika Prusnik Kardum mojstrsko uporablja ponavljanje in ustvarja organsko polisemijo: enake besede v različnih kontekstih pri njej pridobivajo nove pomene, kar je v poeziji, nasičeni z istimi izrazi, redko. Na primer: »Bele breze nam rožljajo, / bele čaplje se smehljajo, / bele gore, beli breg, / bele planike, belo sonce.« Lirska subjektinja očitno občuti svojo predjezikovnost, ki je po Kristevi materinska. Tako v pesmi Sinjebradec poje iz maternice, ob tem pa mesto vstane od mrtvih. Ona ni le pevka pesmi, je subjekt, ki razpada in se vzpostavlja; ali, kot pravi v pesmi, ni pevka te pesmi – je pesem, ki jo pojo. V nekaterih pesmih se zdi, da lirska subjektinja nadaljuje miselni lok, ki ga je odprl Kosovel v pesmi Kons 5 – eksistenci v gnoju in esenci v zlatu – dodaja še tretje, Sveto, Duhovno v Bogu. Pesem Belo, rdeče, črno namreč konča takole: »brez gnoja ni zlata / brez gnoja ni Boga.« Lirska subjektinja je morda ob uvodnih besedah prve pesmi ena izmed žensk, katerih intuitivno, svobodno naravo duši sodobna kultura. A skozi zbirko sprejema lastno senco, sledi intuiciji, se ritualno povezuje z Naravo, ustvarja in zaupa življenjskemu ciklu in se tako ob koncu zbirke izkristalizira kot ženska, ki teče z volkovi. Zbirka Nika Prusnik Kardum Ob reki mmmm je izjemno subtilna, čuteča in prav ničejansko prikimava svoj sveti DA dobremu in zlemu: »To noč sem si obljubila, da bom vse ljubila – / kar je bilo, kar je in kar bo. / Nihče ni kriv za rane sveta, naj jaz bom ta, / kjer te rane se končajo.« Zbirka je zasnovana kot zvočna in telesna izkušnja, ki bralca ne nagovarja neposredno, temveč ga vabi k poslušanju in ponovnemu branju. Kljub temu pa ima tudi nekaj pomanjkljivosti: včasih so verzi neenakomerno dolgi, kar z vidika berljivosti mestoma zmoti tok branja. Zaslužila bi tudi nekoliko boljšo lekturo, saj branje motijo manjše zatipkanine in slovnične pomanjkljivosti. Poenostavitev jezika je ponekod tvegana, npr. verz »Nimam veliko, imam pa vse,« je sprav močan, a v literarnem kontekstu lahko hitro zdrsne iz poetike v geslo. Zbirka se bere tekoče, a občasno ji rahlo zmanjka napetosti, kontrasta in suspenza. Poetika notranjega miru namreč ponekod preglasi konflikt, iz katerega bi lahko vzniknila močnejša napetost. Kljub temu pa zbirka prinaša svežino, saj se iz nje oglasi glas, ki je tako utelešen, da se vrača k naturni oralnosti. Uvaja naravo, ki ni več metafora notranjosti, ampak sogovornica. Pesem, podobno kot pri Zajcu ali Strniši, znova prevzema ritualno funkcijo, ki jo Nika Prusnik Kardum udejanja kot obred stika med Človekom, Duhovnostjo in Naravo. Zbirka Ob reki mmmm je tako močna, kot je ranljiva. Morda ni popolna, je pa ena izmed tistih, ki so žive.
A former NIH director discusses the urgent need to put public health above party lines. Then, a pancreatic cancer survivor reflects on his diagnosis and the complex Whipple procedure that saved his life.
Do the many clinical trials into high-dose vitamin C prove it can actually treat the common cold and cancer, rather than just boost the immune system? Why is there ongoing scepticism? Why are multifactorial chronic diseases so hard to study in clinical trials? What is the right dosage to get the best results from vitamin C?In this episode we have the often misunderstood topic of Vitamin C as an antioxidant to get clear on, particular the high-dose approach and particularly delivered intravenously. Despite a very clear consensus that Vitamin C is a great booster to immune function, research that shows that it helps fight the common cold or flu have been dismissed by doctors and medical researchers; as well as claims that higher doses can increase its efficacy. Other claims that Vitamin C can help fight cardio-vascular disease and even cancer have been with even greater scepticism. So what exactly can vitamin C do to assist our immune function to fight disease, and why is there so much confusion about the answer given the high quantity of clinical trials data?Fortunately today's guest has exactly the right skill set and research knowledge to separate the science from the here-say, medical doctor and orthomolecular medicine researcher, Dr. Richard Z Cheng. Dr. Cheng has a PhD in biochemistry and molecular biology; he's served as a doctor in the US military; he has consulted for the National Cancer Institute, and presented at the National Institute of Health (NIH); he has conducted clinical trials; He is the editor in Chief of the Orthmolecular Medicine New Service; He is also a fellow of the American Academy of Anti- Aging medicine; and has run anti-aging and regenerative medicine clinics in both China and the US for over 20 years.What we discuss:00:00 Intro05:15 Most animals produce Vitamin C in the body, but not primates.06:00 Oxidation & Redox: Giving or receiving an electron.11:00 After reducing oxidation the body recycles it back into vitamin C.14:00 Teamwork: sharing electrons between nutrients and vitamins.18:20 Conventional consensus: good for prevention but not treatment.21:00 Over 80K papers on Vit C on Pub Med!21:30 Linus Pauling Intravenous Vitamin C for cancer and heart disease.27:00 Shortening of common cold and lowering of symptoms - Harri Hemila.29:00 Low dose studies dilute the data on the efficacy of the high dose studies.31:00 Intravenous treatment allows much higher doses safely.33:00 Differences in absorption between IV and oral application.35:20 Pro-oxidant effect only possible at IV high dose.36:30 IV clinical trials.39:20 Cytokine storm cascades in acute respiratory distress.44:00 High Dose IV Vitamin C saved lives in China during Covid 19.50:00 Attacks following Richard's NIH presentation on Vitamin C during covid.57:00 Cardio vascular disease - Vit. C research history.01:01:00 Collagen Synthesis for vascular walls & Vitamin C deficiency.01:07:20 Is the taboo for life style medicine lifting?01:09:30 Issues of gold standard RCT trials not working for multifactorial integrative interventions.01:16:00 Recommendations for preventative use of Vitamin C for listeners. References:E Cameron & Linus Pauling - 'Supplemental ascorbate in the supportive treatment of cancer: Prolongation of survival times in terminal human cancer', 1976E.T. Creagan, 'Failure of high-dose vitamin C (ascorbic acid) therapy to benefit patients with advanced cancer', 1979Harri Hemilä - over 200 meta-analyses and clinical trialsPing Chen et al. 'Pharmacokinetic Evaluation of Intravenous Vitamin C'Richard Z Cheng, ‘Can early and high intravenous dose of vitamin C prevent and treat coronavirus disease 2019 (COVID-19)?'KU Cancer Center researchers announce study of high-dose intravenous vitamin C to treat muscle-invasive bladder cancer, 2024National Cancer Institute overview of IV Vitamin C cancer research.
Natasha is joined by Dr. Lisa Diamond and Dr. Scout on this episode of the Natasha Helfer Podcast. This is a powerful episode as, in Lisa's words: "Scout and I have witnessed the entire birth and now destruction of the field of queer and trans mental and physical health (Scout is 60, I'm 54), so we have lived through this whole weird arc of seeing lgbtq health become a legitimate profession, and now it's being threatened—it's both personally and professionally devastating for both of us to witness this happening. "It is astounding that at a time when we recently survived a global pandemic that left so many people feeling isolated in ways that has profoundly affected our mental and physical health… and at a time when we have very clear data on the risk of suicide and lessened wellbeing for the LGBTQI+ community due to societal discrimination… that the government is choosing to dismantle and destroy so many departments/entities meant to support the health, science and data collection of ALL Americans." Dr. Diamond and Dr. Scout have created a survey for anyone affected by the current administration. Please consider filling it out. "We launched the study with zero funding, it's driven by pure love and panic, and it's affecting EVERYONE who loves or works with queer or trans people, including family members, friends, social workers, physicians, school, teachers, therapist, educators, EVERYONE. All of us are going through something, and we are going through this at the same time that the federal government has CEASED all data collection on our health. So Scout and I figured "OK, you don't wanna do this? We're just gonna have to do it ourselves." Go here to fill out the survey: https://csbsutah.co1.qualtrics.com/jfe/form/SV_9WyKRPONJuL67Yy?fbclid=IwY2xjawOEdthleHRuA2FlbQIxMABicmlkETFoOW43aDJMdnNGb1kwSThZc3J0YwZhcHBfaWQQMjIyMDM5MTc4ODIwMDg5MgABHkWvMqhUx7OYFY_0kbvt2yVu911j1Ch5DAnsBloLDDgUw1CHSZ3BRNwBhq3A_aem_2e27bX8Xk_kP7utbPv482g Also, if you're an organization that would like to partner with this project reach out to: research@cancer-network.com From Natasha: I loved Lisa's reminder that we survive oppression and destruction through connection. This is a small thing we can do to make a difference and that in of itself is healing and empowering. Please take the 20-25 minutes to fill out this survey. And please forward it to anyone you know who is impacted. Scout, PhD (they/he) is the Executive Director of the National LGBTQI+ Cancer Network and the principal investigator of both the CDC-funded LGBTQI+ tobacco-related cancer disparity network and Out: The National Cancer Survey. They spend much of their time providing technical assistance for tobacco and cancer focusing agencies expanding their reach and engagement with LGBTQI+ populations. Scout has a long history in health policy analysis and a particular interest in ensuring research and surveillance activities include LGBTQI+ people. They have faculty appointments at Dartmouth Cancer Center and Boston University's school of public health. They are a member of FDA's Tobacco Products Scientific Advisory Committee, on the Advisory Panel for NIH's All of Us initiative, and a former member of NIH Council of Councils as well as former Co-Chair of the NIH Sexual and Gender Minority Research Office Work Group. Their work has won them recognition from the U.S. House of Representatives, two state governments, and many city governments. Scout is an openly nonbinary and trans father of three, an avid hiker, and is currently training for the aptly named Dopey Challenge races at Disney. Lisa M. Diamond, Ph.D., is a Distinguished Professor of Psychology and Gender Studies at the University of Utah and a past president of the International Academy for Sex Research. For nearly 30 years, she has studied gender and sexuality across the lifespan, with current work centered on social safety and its impact on the health and well-being of LGBTQ+ individuals. Dr. Diamond is internationally recognized for her pioneering research on sexual fluidity, including her award-winning book Sexual Fluidity (Harvard University Press). She co-edited the first APA Handbook of Sexuality and Psychology, is a fellow of two APA divisions, and has published over 150 scholarly works. Her research has been supported by major national foundations, and she has delivered more than 200 invited talks worldwide, including a TED Talk with over 700,000 views. — Join Natasha February 11-17th 2026 on a cruise leaving out of Tampa, Florida. You can grab a package and work with Natasha on the ship. Sign up before January 1st and you get the early bird special: Natasha packages: $750 per couple $675 per couple - early bird (before January 1st) Payment plans are available. For further questions, email Mimi at unleashedvacations@gmail.com. Book now to make sure you don't miss out! See you on board. — To help keep this podcast going, please consider donating at natashahelfer.com and share this episode. To watch the video of this podcast, you can subscribe to Natasha's channel on Youtube and follow her professional Facebook page at natashahelfer LCMFT, CST-S. You can find all her cool resources at natashahelfer.com. The information shared on this program is informational and should not be considered therapy. This podcast addresses many topics around mental health and sexuality and may not be suitable for minors. Some topics may elicit a trigger or emotional response so please care for yourself accordingly. The views, thoughts and opinions expressed by our guests are their own and do not necessarily reflect the views or feelings of Natasha Helfer or the Natasha Helfer Podcast. We provide a platform for open and diverse discussions, and it is important to recognize that different perspectives may be shared. We encourage our listeners to engage in critical thinking and form their own opinions. The intro and outro music for these episodes is by Otter Creek. Thank you for listening. And remember: Symmetry is now offering Ketamine services. To find out more, go to symcounseling.com/ketamine-services. There are also several upcoming workshops. Visit natashahelfer.com or symcounseling.com to find out more.
What if the biggest threat to our survival isn't the next virus, but our failure to learn from the last one? In this episode, Dr. Michael Osterholm, Regents Professor and Director of the Center for Infectious Disease Research and Policy (CIDRAP) at the University of Minnesota, explains why America's public health system is dangerously underprepared for the next major outbreak. He shares how misinformation and political interference have eroded confidence in science, leaving critical institutions like the CDC and NIH struggling to fulfill their missions. Dr. Osterholm discusses lessons from COVID-19 and why failing to apply them could cost millions of lives in the future. He also explores the promise of universal vaccines, the need for sustained investment in pandemic defense, and how rebuilding public trust starts with humility, transparency, and truth-telling. Tune in to hear what it will really take to prepare for “the big one. Resources Connect with and follow Dr. Michael Osterholm on LinkedIn. Follow the University of Minnesota on LinkedIn! Follow the Center for Infectious Disease Research and Policy (CIDRAP) on LinkedIn and visit their website! Learn more about the Vaccine Integrity Project here! Pick up any of Dr. Osterholm's books here! Check out the Osterholm Update podcast! Learn more about your ad choices. Visit megaphone.fm/adchoices
Welcome to the NeurologyLive® Mind Moments® podcast. Tune in to hear leaders in neurology sound off on topics that impact your clinical practice. In this episode, "NEALS 2025: Takeaways That Matter for ALS Care," ALS experts Jinsy Andrews, MD, MSc, and James Berry, MD, MPH, reflect on key themes from the 2025 NEALS Annual Meeting, now reintroduced as the Network of Excellence for ALS. They discuss format changes that elevated lightning science, the expanding gene therapy pipeline, and a growing slate of NEALS-affiliated trials. The conversation highlights updates from the HEALEY Platform Trial, the MY-MATCH biomarker-guided precision trial, SOD1 program data, and new antisense and viral vector therapies aimed at sporadic ALS. They also explore the impact of Act for ALS on trial access, the ALL ALS biospecimen repository, and NIH-supported expanded access cohorts. The discussion closes with insights on combination therapy strategies, genetic subtypes, presymptomatic enrollment, and how new collaborations, digital endpoints, and infrastructure advances are shaping momentum heading into 2026. Looking for more Neuromuscular discussion? Check out the NeurologyLive® Neuromuscular clinical focus page. Episode Breakdown: 1:05 – Reflections on meeting highlights and NEALS rebranding into a global network 5:00 – Notable NEALS-affiliated trials and promising new mechanisms in ALS care 12:45 – Combination therapy strategies and future approaches in ALS research 15:20 – Neurology News Minute 18:00 – Expanding clinical trial access for rare and genetic ALS subtypes 22:10 – Building momentum and expectations for the 2026 NEALS Annual Meeting The stories featured in this week's Neurology News Minute, which will give you quick updates on the following developments in neurology, are further detailed here: FDA Approves Doxecitine and Doxribtimine Combination Therapy as First Treatment for Thymidine Kinase 2 Deficiency Supplemental New Drug Application Submitted for AXS-05 as Treatment for Alzheimer Disease Agitation BTK Inhibitor Fenebrutinib Meets Primary End Points in Phase 3 Trials for Both Relapsing and Primary Progressive MS Thanks for listening to the NeurologyLive® Mind Moments® podcast. To support the show, be sure to rate, review, and subscribe wherever you listen to podcasts. For more neurology news and expert-driven content, visit neurologylive.com.
What if blockbuster weight-loss drugs and a broken food system are two sides of the same story? We sit down with Dr. David Harlan—physician, researcher, and former NIH diabetes branch chief—to trace the unlikely path from the “incretin effect” to GLP-1 therapies that are transforming care for type 2 diabetes and obesity. Along the way, we ask harder questions about incentives, access, and why lifestyle still matters even when the medicine is powerful.Dr. Harlan breaks down how GLP-1 receptor agonists amplify insulin release, quiet cravings, and drive meaningful weight loss—often alongside better blood pressure, improved A1C, and fewer heart events. He explains the Gila monster connection, why weekly injections replaced multiple daily shots, and what the latest safety data actually shows. We get candid about what happens when people stop these drugs, why genetics complicate the “just try harder” narrative, and how brain chemistry shapes appetite, compulsion, and energy.Then we zoom out to the policy level: the rise of food deserts, cheap ultra-processed calories, and the paradox of publicly funding both the problem and the fix. We explore practical steps that work in the real world—SKU-controlled health savings accounts, everyday movement campaigns, healthier default options in public spaces, and community gardens and sidewalks that make active living normal again. The throughline is simple and human: use the science to help people now, and rebuild the environment so fewer need the medicine later.If you care about diabetes, obesity, prevention, or the economics shaping our plates and prescriptions, this conversation offers clarity and a path forward. Support the show by subscribing, sharing with a friend, and leaving a review with the one insight you'll apply this week.Support the showEngage the conversation on Substack at The Common Bridge!
About this episode: Between lawsuits, layoffs, and lags in funding, NIH has undergone significant changes in how it reviews and approves grant proposals for critical research. In this episode: Jeremy Berg, a former NIH leader, talks about what's changed and what's to come for indirect cost reimbursements, funding approvals, and the scientific research ecosystem as a whole. Guests: Jeremy M. Berg, PhD, is a professor of computational and systems biology at the University of Pittsburgh, where he is also the Associate Senior Vice Chancellor of Science Strategy and Planning. He previously served as the Director of the National Institute for General Medical Sciences at NIH. Host: Lindsay Smith Rogers, MA, is the producer of the Public Health On Call podcast, an editor for Expert Insights, and the director of content strategy for the Johns Hopkins Bloomberg School of Public Health. Show links and related content: Appeals court judges seem skeptical of Trump administration's defense of capping NIH overhead payments—STAT Trump order gives political appointees vast powers over research grants—Nature Life-saving medicines begin in the basic research DOGE wants to stop funding—Pittsburgh Post-Gazette Transcript information: Looking for episode transcripts? Open our podcast on the Apple Podcasts app (desktop or mobile) or the Spotify mobile app to access an auto-generated transcript of any episode. Closed captioning is also available for every episode on our YouTube channel. Contact us: Have a question about something you heard? Looking for a transcript? Want to suggest a topic or guest? Contact us via email or visit our website. Follow us: @PublicHealthPod on Bluesky @JohnsHopkinsSPH on Instagram @JohnsHopkinsSPH on Facebook @PublicHealthOnCall on YouTube Here's our RSS feed Note: These podcasts are a conversation between the participants, and do not represent the position of Johns Hopkins University.
Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comIn this fascinating episode, Dr. Gabrielle Lyon talks with neuroscientist Dr. Ben Rein, PhD (author of Why Brains Need Friends), about the science of social connection, emotion, and cognitive health. Dr. Rein, an expert in neurobiology and psychedelic research, reveals the cutting-edge studies that explain why loneliness is as damaging as smoking and how our digital world is affecting our brain's ability to connect.They discuss the neurochemistry of love, the controversial use of MDMA in therapy, and whether AI can ever truly replace human intimacy. This conversation provides an essential look at the biological drivers of happiness, performance, and long-term brain health.Chapter Markers:0:00 - MDMA (Molly): The History & Therapeutic Benefits 5:59 - The Legal Status of MDMA for PTSD 6:44 - The Safety and Effectiveness of MDMA in Clinical Trials 8:29 - PTSD (The Amygdala Alarm) 9:41 - How MDMA Soothes the Amygdala to Access Memory 11:42 - Is There an Alternative to MDMA? (Ketamine's Mechanism) 13:16 - Ketamine and Neuroplasticity for Depression 15:48 - Botox and Empathy: 18:12 - The Problem of Volume: How Screens Depersonalize Interaction 19:48 - The Virtual Disengagement Hypothesis Explained 25:00 - Defining Cognitive and Emotional Empathy 29:43 - MDMA's Link to Serotonin & Social Reward 31:04 - Do SSRIs Have Pro-Social Effects? 36:10 - The Science of Likability and "Easy to Read" Faces 40:10 - Top 3 Ways to Be More Likable49:49 - The Likability Gap: Why You Underestimate How Well-Liked You Are 56:59 - The Neurobiology of Oxytocin, Dopamine, and Serotonin1:09:23 - The Goldilocks Zone of Empathy 1:15:58 - Narcolepsy 1:18:16 - Alcohol: Why the Neurotoxin is Bad for Brain Health 1:21:47 - Exercise and Neurogenesis1:22:27 - Sex, Orgasm, and Oxytocin Release 1:25:06 - Oxytocin During Childbirth Who is Ben Rein:Dr. Ben Rein is an award-winning neuroscientist and Chief Science Officer of the Mind Science Foundation, where he supports early-career researchers in neuroscience. He earned his PhD from SUNY Buffalo and completed postdoctoral training at Stanford University, publishing over 20 peer-reviewed papers on autism, empathy, MDMA, and digital behavior. Recognized by the NIH, the Society for Neuroscience, and Sigma Xi, he also serves as a scientific advisor to more than 20 organizations. With over one million followers and 75 million video views, Dr. Rein is celebrated for making neuroscience accessible to the public and has been featured by outlets such as Good Morning America, ABC News, and PopularMechanics.Thank you to our sponsors:BodyHealth: Use code LYON20 to get 20% off your first order https://www.bodyhealthaffiliates.com/73L4QL3/7XDN2/BON CHARGE Holiday Sale https://boncharge.com for 25% off Pique 20% off for life: https://Piquelife.com/DRLYONFind Ben Rein at: Website: https://www.benrein.com/Instagram: https://www.instagram.com/dr.benrein/#TikTok: https://www.tiktok.com/@dr.benrein?lang=enFacebook:
Behind every medical breakthrough for kids is usually a long history of research advances. Research is incremental, and new therapies exist, thanks to questions that are asked in science laboratories. Those investigators not only asked the hard questions but also found the funding to answer them. What happens when that funding starts to disappear? Research drives progress in pediatric medicine from vaccines to breakthrough treatments for rare diseases. That progress is currently at risk. Cuts and cancellations in key federal research programs, including CDC and NIH funding, threaten to stall discoveries and disproportionately impact pediatric investigators. In this episode, we dig into what's happening with child health research funding, why it matters for every pediatrician, and where the greatest opportunities for advocacy lie. For this episode, we are joined by two experts at the forefront of this conversation. Joe St. Geme, MD, is the Physician in Chief at the Children's Hospital of Philadelphia, as well as the President of the CHOP Practice Association. He is also a professor at the University of Pennsylvania Perelman School of Medicine. Zach Zaslow is the Vice President of Advocacy and Community Health at Children's Hospital Colorado. Some highlights from this episode include: The status of pediatric research funding How pediatric research directly impacts community pediatricians What current threats exist How providers can advocate for their patients and families For more information on Children's Colorado, visit: childrenscolorado.org.
Want to share your feedback? Send us a message!Dr. Shahriar SheikhBahaei, Assistant Professor of Neurobiology and Behavior at Stony Brook University, joins host Sara MacIntyre, M.A., CCC-SLP, to discuss emerging research exploring the cellular and neurobiological mechanisms underlying stuttering. Dr. SheikhBahaei shares his journey from lived experience with stuttering to leading a neuroscience research lab investigating how glial cells, particularly astrocytes, contribute to motor control and speech-related circuits.The conversation delves into several recent studies from his lab that utilize mouse models to uncover how alterations in astrocyte function and iron regulation may relate to the neural pathways involved in stuttering. Dr. SheikhBahaei walks listeners through the background, scientific rationale, and key findings of these studies, highlighting what they reveal about the non-vocal motor aspects of stuttering and how this basic science may inform future directions in understanding and treatment.The episode concludes with reflections on bridging laboratory research with the lived experiences of people who stutter and fostering collaboration among scientists, clinicians, and the stuttering community.Resources discussed:SheikhBahaei, S., et al. (2025). Non-vocal motor deficits in a transgenic mouse model linked to stuttering disorders. bioRxiv. https://www.biorxiv.org/content/10.1101/2025.08.08.669441v2SheikhBahaei, S., et al. (2025). Iron dysregulation in mice engineered with a mutation associated with stuttering. bioRxiv. https://www.biorxiv.org/content/10.1101/2025.07.30.667752v1SheikhBahaei, S., et al. (2024). Scientists, society, and stuttering: A multi-stakeholder approach. International Journal of Clinical Practice. https://onlinelibrary.wiley.com/doi/full/10.1111/ijcp.13678Shahriar SheikhBahaei, Ph.D., is a neuroscientist and faculty member at Stony Brook University. His research focuses on how the brain controls complex motor behaviors such as speech and breathing, particularly focusing on the role of astrocytes in neural circuits. Growing up with stuttering has influenced his lifelong pursuit to understand the neurobiology of speech and communication. He completed his Ph.D. in Neuroscience through a joint program at University College London and the National Institutes of Health (NIH). He later became one of the first Independent Research Scholars at NIH, where he established his own lab. At Stony Brook University, he continues to investigate the cellular and circuit foundations of speech disorders while also mentoring the next generation of scientists and advocating for more inclusive perspectives on communication.
Headlines shout certainty while the data whispers, and that gap can cost us wisdom. We dive into what real research looks like, how to separate signal from noise, and why the difference between correlation and causation matters for your health, your choices, and your credibility. From flashy anecdotes and AI-polished videos to the quiet rigor of controls, sample sizes, and replication, we walk through a practical, plain-language guide to spotting trustworthy studies without getting lost in jargon.We talk about the strengths and limits of meta-analyses, the importance of peer review, and why timeframes can make or break a claim—short-term happiness can look very different seven years later. Funding isn't neutral either, so we show you how incentives shape headlines and why early “breakthroughs” often fade when larger trials arrive. You'll hear how to use public resources like NIH repositories, when to lean on academic libraries, and how to ask better questions of your doctor or any expert you trust. Along the way, we call out common logical fallacies, the lure of echo chambers, and the subtle ways our pride and emotions tug us toward bad conclusions.Underneath it all is a deeper commitment: caring about truth is an act of stewardship. We want to make decisions with integrity, serve our neighbors with reliable information, and admit honestly when the evidence just isn't there yet. That blend of diligence and humility keeps us grounded—pursuing knowledge while recognizing our limits, weighing evidence without surrendering compassion, and trusting God when certainty runs out.If this conversation helps you think more clearly about research and real-world decisions, share it with a friend. Subscribe for more thoughtful episodes, and leave a review to tell us what question you want us to tackle next.Support the showThe ministry of Christian Life Resources promotes the sanctity of life and reaches hearts with the Gospel. We invite you to learn more about the work we're doing: https://christianliferesources.com/
Overview: In this episode, Dr Gina Brown and Dr Sahar Khalili draw on their expertise in HIV prevention to provide an overview of the current PrEP landscape in the United States. They highlight advancements in HIV prevention and emphasize the importance of targeted programs to address disparities in access and uptake across population groups and geographic regions. The views expressed are those of the panelist(s) and not necessarily Gilead Sciences, Inc. The information provided in this podcast is not intended to be and should not be understood to provide medical advice. Listeners should note that our discussions in this episode are relevant to the USA only and may not be appropriate for other regions. This episode was recorded in August 2025 and the content reflects the information available at that time. Guest: Gina Brown, MD; Sahar Khalili, PharmD For more information, please visit: https://www.pri-med.com/clinical-resources/curriculum/hiv-in-focus References ACOG. Preexposure prophylaxis for the prevention of human immunodeficiency virus. 2024. Available from: https://www.acog.org/clinical/clinical-guidance/practice-advisory/articles/2022/06/preexposure-prophylaxis-for-the-prevention-of-human-immunodeficiency-virus (Accessed June 25, 2025). ADAP Directory. About. 2024. Available from: https://adap.directory/about (Accessed June 25, 2025). Aidsmap. Condoms. 2023. Available from: https://www.aidsmap.com/about-hiv/condoms#toc-how-effective-are-condoms (Accessed June 25, 2025). AIDSVu. AIDSVu releases new PrEP data and launches PrEPVu.org, a new PrEP equity platform. 2024. Available from: https://aidsvu.org/news-updates/aidsvu-releases-new-prep-data-and-launches-prepvu-org-a-new-prep-equity-platform/ (Accessed June 25, 2025). AIDSVu.org was developed by the Rollins School of Public Health at Emory University in partnership with Gilead Sciences, Inc. AIDSVu. AIDSVu releases 2024 PrEP use data showing growing use across the U.S. 2025. Available from: https://aidsvu.org/news-updates/aidsvu-releases-2024-prep-use-data-showing-growing-use-across-the-u-s/ (Accessed July 18, 2025). AIDSVu.org was developed by the Rollins School of Public Health at Emory University in partnership with Gilead Sciences, Inc. AIDSVu. Location profiles: South. 2025. Available from: https://map.aidsvu.org/profiles/region/south/prevention-and-testing#1-2-PnR (Accessed July 31, 2025). AIDSVu.org was developed by the Rollins School of Public Health at Emory University in partnership with Gilead Sciences, Inc. AIDSVu. PrEP use significantly associated with decreasing new HIV diagnoses across U.S. states. 2025. Available from: https://aidsvu.org/news-updates/prep-use-significantly-associated-with-decreasing-new-hiv-diagnoses-across-u-s-states/ (Accessed June 25, 2025). AIDSVu.org was developed by the Rollins School of Public Health at Emory University in partnership with Gilead Sciences, Inc. Baeten J et al. Curr HIV/AIDS Rep 2013;10:142–51. 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Overview: In this episode, Dr Joel Gallant gives a history of antiretroviral therapy and HIV drug resistance, drawing on his personal and professional experience beginning in the early 1980s. The views expressed are those of the panelist and not necessarily Gilead Sciences, Inc. The information provided in this podcast is not intended to be and should not be understood to provide medical advice. Listeners should note that our discussions in this episode are relevant to the USA only and may not be appropriate for other regions. This episode was recorded in August 2023 and the content reflects the information available at that time. Guest: Joel Gallant, MD, MPH For more information, please visit: https://www.pri-med.com/clinical-resources/curriculum/hiv-in-focus References AIDSVu.org. New HIV diagnoses. 2023. 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Available from: https://doi.org/10.1056/NEJMoa035026 Landovitz RJ, Donnell D, Clement ME et al. Cabotegravir for HIV prevention in cisgender men and transgender women. N Engl J Med 2021;385:595–608. Available from: https://doi.org/10.1056/NEJMoa2101016 Larder BA, Darby G, Richman DD. HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy. Science 1989;243:1731–4. Available from: https://doi.org/10.1126/science.2467383 Lau B, Gange SJ, Moore RD. Risk of non-AIDS-related mortality may exceed risk of AIDS-related mortality among individuals enrolling into care with CD4+ counts greater than 200 cells/mm3. J Acquir Immune Defic Syndr 2007;44:179–87. Available from: https://doi.org/10.1097/01.qai.0000247229.68246.c5 Lucas C. The San Francisco model and the nurses of Ward 5B. Lancet HIV 2019;6:E819. Available from: https://doi.org/10.1016/S2352-3018(19)30267-X Madruga JV, Cahn P, Grinsztejn B et al. 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Clin Infect Dis 2023;76:1646–54. Available from: https://doi.org/10.1093/cid/ciad020 Pollak EB, Parmar M. Indinavir. In: StatPearls. Treasure Island (FL): StatPearls Publishing, 2023. Available from: https://www.ncbi.nlm.nih.gov/books/NBK554396/ (Accessed May 19, 2025) Richman DD, Fischl MA, Grieco MH et al. The toxicity of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial. N Engl J Med 1987;317:192–7. Available from: https://doi.org/10.1056/nejm198707233170402 Schmit JC, Ruiz L, Clotet B et al. Resistance-related mutations in the HIV-1 protease gene of patients treated for 1 year with the protease inhibitor ritonavir (ABT-538). AIDS 1996;10:995–9. Available from: https://doi.org/10.1097/00002030-199610090-00010 Siliciano JD, Kajdas J, Finzi D et al. Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells. Nat Med 2003;9:727–8. 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Overview: In this episode, Toyin Nwafor, MD, and Christian B Ramers, MD, draw on their experience in primary care, HIV and HIV prevention to highlight missed opportunities for HIV prevention and discuss strategies to help address gaps in the HIV care continuum. The views expressed are those of the panelist(s) and not necessarily Gilead Sciences, Inc. The information provided in this podcast is not intended to be and should not be understood to provide medical advice. Listeners should note that our discussions in this episode are relevant to the USA only and may not be appropriate for other regions. This episode was recorded in August 2025 and the content reflects the information available at that time. Guest: Toyin Nwafor, MD; Christian B Ramers, MD, MPH, FIDSA, AAHIVS For more information, please visit: https://www.pri-med.com/clinical-resources/curriculum/hiv-in-focus References AIDSVu.org. Prevalence in the United States. 2022. Available from: https://map.aidsvu.org/ (Accessed June 25, 2025). AIDSVu.org was developed by the Rollins School of Public Health at Emory University in partnership with Gilead Sciences, Inc. Baeten J et al. Curr HIV/AIDS Rep 2013;10:142–51. CDC. Clinical testing guidance for HIV. 2025. Available from: https://www.cdc.gov/hivnexus/hcp/diagnosis-testing/index.html (Accessed June 25, 2025). CDC. Discussing sexual health with your patients. 2025. Available from: https://www.cdc.gov/hivnexus/hcp/sexual-history/index.html (Accessed June 25, 2025). CDC.gov. HIV diagnoses, deaths, and prevalence. 2025. Available from: https://www.cdc.gov/hiv-data/nhss/hiv-diagnoses-deaths-prevalence.html (Accessed June 25, 2025). CDC. National HIV prevention and care objectives: 2025 update. 2025. Available from: https://www.cdc.gov/hiv-data/nhss/national-hiv-prevention-and-care-objectives-2025.html (Accessed June 25, 2025). CDC. Preexposure prophylaxis for the prevention of HIV infection in the United States – 2021 update: a clinical practice guideline. 2021. Available from: https://stacks.cdc.gov/view/cdc/112360 (Accessed June 25, 2025). Doblecki-Lewis S et al. J Int Assoc Provid AIDS Care 2019;18:2325958219848848. DHHS. Guidelines for the use of antiretroviral agents in adults and adolescents with HIV. 2024. Available from: https://clinicalinfo.hiv.gov/sites/default/files/guidelines/documents/adult-adolescent-arv/guidelines-adult-adolescent-arv.pdf (Accessed June 25, 2025). HIV.gov. Key EHE strategies. 2024. Available from: https://www.hiv.gov/federal-response/ending-the-hiv-epidemic/key-strategies (Accessed June 2, 2025). HIV.gov. HIV treatment as prevention. 2023. Available from: https://www.hiv.gov/tasp (Accessed June 25, 2025). HIV.gov. US statistics. 2025. Available from: https://www.hiv.gov/hiv-basics/overview/data-and-trends/statistics (Accessed May 21, 2025). HIV.gov. Viral suppression and undetectable viral load. 2025. Available from: https://www.hiv.gov/hiv-basics/staying-in-hiv-care/hiv-treatment/viral-suppression (Accessed July 18, 2025). HIV.gov. Who is at risk for HIV. 2025. Available from: https://www.hiv.gov/hiv-basics/overview/about-hiv-and-aids/who-is-at-risk-for-hiv (Accessed June 25, 2025). Johns Hopkins Bloomberg School of Public Health. What to know about PrEP. 2025. Available from: https://publichealth.jhu.edu/2025/who-needs-prep-for-hiv-prevention (Accessed June 25, 2025). Kamis KF et al. Open Forum Infect Dis 2019;6:ofz310. KFF. HIV testing in the United States. 2024. Available from: https://www.kff.org/hiv-aids/hiv-testing-in-the-united-states/ting in the United States | KFF (Accessed August 26, 2025). NIH. HIV and sexually transmitted infections (STIs). 2021. Available from: https://hivinfo.nih.gov/understanding-hiv/fact-sheets/hiv-and-sexually-transmitted-infections-stis (Accessed June 25, 2025). Ramchandani MS et al. Curr HIV/AIDS Rep 2019;16:244–56. Saag MS et al. JAMA 2018;320:379–96. Sweeney P et al. J Acquir Immune Defic Syndr 2019;82(Suppl 1):S1–5. The White House. National HIV/AIDS strategy for the United States 2022–2025. 2021. Available from: https://files.hiv.gov/s3fs-public/NHAS-2022-2025.pdf (Accessed June 25, 2025). UNAIDS.org. Recommended 2030 targets for HIV. 2025. Available from: https://www.unaids.org/en/recommended-2030-targets-for-hiv (Accessed August 26, 2025). United States Census Bureau. National population by characteristics: 2020-2024. 2024. Available from: https://www.census.gov/data/tables/time-series/demo/popest/2020s-national-detail.html (Accessed June 25, 2025). United States Census Bureau. United States Population Growth by Region. 2025. Available from: https://www.census.gov/popclock/ (Accessed June 25, 2025). Yumori C et al. Sex Transm Dis 2021;48:32–6.
Overview: In this episode, Dr Toyin Nwafor and Dr Andrew Zolopa provide an overview of the HIV treatment landscape both globally and in the United States. They highlight the current gaps in the HIV care continuum, emphasize the importance of rapid start and viral suppression in reducing HIV transmission through sex and describe initiatives and strategies aimed at closing these gaps to help end the HIV epidemic in the United States. The views expressed are those of the panelist(s) and not necessarily Gilead Sciences, Inc. The information provided in this podcast is not intended to be and should not be understood to provide medical advice. Listeners should note that our discussions in this episode are relevant to the USA only and may not be appropriate for other regions. This episode was recorded in August 2025 and the content reflects the information available at that time. Guest: Toyin Nwafor, MD; Andrew Zolopa, MD For more information, please visit: https://www.pri-med.com/clinical-resources/curriculum/hiv-in-focus References AETC. Rapid (immediate) ART initiation and restart: guide for clinicians. 2023. Available from: https://aidsetc.org/resource/rapid-immediate-art-initiation-restart-guide-clinicians (Accessed June 25, 2025). Baxter A et al. J Acquir Immune Defic Syndr 2025;99:47–54. CDC. About ending the HIV epidemic in the US. 2024. Available from: https://www.cdc.gov/ehe/php/about/index.html (Accessed June 25, 2025). CDC. Clinical testing guidance for HIV. 2025. Available from: https://www.cdc.gov/hivnexus/hcp/diagnosis-testing/index.html (Accessed June 25, 2025). CDC. Getting tested for HIV. 2025. Available from: https://www.cdc.gov/hiv/testing/index.html#cdc_testing_why_get_tested-why-get-tested (Accessed June 25, 2025). CDC. Laboratory testing for the diagnosis of HIV infection. 2014. Available from: https://stacks.cdc.gov/view/cdc/23446 (Accessed June 25, 2025). CDC. National HIV prevention and care objectives: 2025 update. 2025. Available from: https://www.cdc.gov/hiv-data/nhss/national-hiv-prevention-and-care-objectives-2025.html (Accessed June 25, 2025). Delaney KP et al. Am J Prev Med 2021;61(5 Suppl 1):S6–S15. DHHS. Guidelines for the use of antiretroviral agents in adults and adolescents living with HIV. 2024. Available from: https://clinicalinfo.hiv.gov/sites/default/files/guidelines/documents/adult-adolescent-arv/guidelines-adult-adolescent-arv.pdf (Accessed June 25, 2025). HIV.gov. EHE overview. 2025. Available from: https://www.hiv.gov/federal-response/ending-the-hiv-epidemic/overview (Accessed June 25, 2025). HIV.gov. Global statistics. 2025. Available from: https://www.hiv.gov/hiv-basics/overview/data-and-trends/global-statistics (Accessed June 25, 2025). HIV.gov. HIV Care Continuum. 2025. Available from: https://www.hiv.gov/federal-response/other-topics/hiv-aids-care-continuum (Accessed June 25, 2025). HIV.gov. Key EHE strategies. 2024. Available from: https://www.hiv.gov/federal-response/ending-the-hiv-epidemic/key-strategies (Accessed June 25, 2025). HIV.gov. US statistics. 2025. Available from: https://www.hiv.gov/hiv-basics/overview/data-and-trends/statistics (Accessed June 25, 2025). HIV.gov. Viral suppression and undetectable viral load. 2025. Available from: https://www.hiv.gov/hiv-basics/staying-in-hiv-care/hiv-treatment/viral-suppression (Accessed June 25, 2025). Mirzazadeh A et al. PLoS Med 2022;19:e1003940. NIH. HIV testing. 2025. Available from: https://hivinfo.nih.gov/understanding-hiv/fact-sheets/hiv-testing (Accessed June 25, 2025). Palacio-Vieira J et al. BMC Public Health 2021;21:1596. Saag MS et al. JAMA 2018;320:379–96. The White House. National HIV/AIDS strategy for the United States 2022–2025. 2021. Available from: https://files.hiv.gov/s3fs-public/NHAS-2022-2025.pdf (Accessed June 25, 2025). WHO. Supporting re-engagement in HIV treatment services: policy brief. 2024. Available from: https://www.who.int/publications/i/item/9789240097339 (Accessed June 25, 2025).
Lawrence M. Schell is a Distinguished Professor in the Department of Anthropology and the College of Integrated Health Sciences at the University at Albany, SUNY, with a joint appointment in the Department of Epidemiology and Biostatistics. His research explores the interrelationship between biology and culture, with a particular focus on how contemporary urban environments shape human health and development. Dr. Schell's early work examined noise as a form of urban stress, investigating its effects on prenatal and postnatal growth. He later expanded his research to include pollutants such as polychlorinated biphenyls (PCBs) and lead, situating these exposures within the broader context of urban adaptation and health disparities. The study of lead exposure in Albany, NY, examined its influence on child physical and cognitive development, with attention to maternal nutrition and other factors that affect the transfer of lead from mother to fetus. In partnership with the Akwesasne Mohawk Nation he has recently completed three major projects. The first examined how PCBs that were used in manufacturing affect physical and sexual development during adolescence. His second project followed up the adolescents in project 1 to learn how exposure had influenced their transition into adulthood. The third project, also conducted with the Akwesasne community, explored how environmental pollutants may impact reproductive health and fertility among women. Through this work, Dr. Schell highlights the urban environment as a critical frontier for human adaptation, emphasizing the challenges posed by pollution, stress, and other features of modern city life while recognizing that these challenges are inequitably distributed in society. In 2004 Schell established a research center at Albany with NIH support to grow research on health disparities. Continued NIH support culminated in an endowment grant that will support the center and the development of health disparities research for many years to come. ------------------------------ Contact the Sausage of Science Podcast and the Human Biology Association: Facebook: facebook.com/groups/humanbiologyassociation/, Website: humbio.org, Twitter: @HumBioAssoc Chris Lynn, Co-Host Website: cdlynn.people.ua.edu/, E-mail: cdlynn@ua.edu, Twitter:@Chris_Ly Courtney Manthey, Guest-Co-Host, Website: holylaetoli.com/ E-mail: cpierce4@uccs.edu, Twitter: @HolyLaetoli Anahi Ruderman, SoS Co-Producer, HBA Junior Fellow, E-mail: ruderman@cenpat-conicet.gob.ar
Listen to this powerful interview with Dr. David Fajgenbaum who has an incredible new memoir, "Chasing My Cure: A Doctor's Race to Turn Hope into Action". David's story is truly unique; it's a tale of learning to live, while dying: a universally relatable story about getting up and fighting back after life knocks you down.A former Georgetown quarterback nicknamed "The Beast," David Fajgenbaum was also a force in medical school, where he was known for his unmatched mental stamina. But things changed dramatically when he began suffering from inexplicable fatigue. In a matter of weeks, his organs were failing and he was read his last rites. Doctors were baffled over a condition they had yet to even diagnose; floating in and out of consciousness, Fajgenbaum prayed for the equivalent of a game day overtime: a second chance.Miraculously, Fajgenbaum survived, but only to endure repeated near-death relapses from what would eventually be identified as a form of Castleman disease—an extremely deadly and rare condition that acts like a cross between cancer and an autoimmune disorder. When he relapsed on the only drug in development and realized that the medical community was unlikely to make progress in time to save his life, Fajgenbaum turned his desperate hope for a cure into concrete action: between hospitalizations he studied his own charts and tested his own blood samples, looking for clues that could unlock a new treatment. With the help of family, friends and mentors, he also reached out to other Castleman disease patients and physicians, and eventually came up with an ambitious plan to crowdsource the most promising research questions and recruit world- class researchers to tackle them; instead of waiting for the scientific stars to align, he proposed to align them himself.More than five years later and now married to his college sweetheart, his hard work has paid off: a treatment that he identified has induced a tentative remission and his novel approach to collaborative scientific inquiry has become a blueprint for advancing rare disease research. His incredible story demonstrates the potency of hope, and what can happen when forces of determination, love, family, faith and serendipity collide.David Fajgenbaum, MD, MBA, MSc is one of the youngest individuals to be appointed to the faculty at Penn Medicine. Co- founder and executive director of the Castleman Disease Collaborative Network (CDCN) and an NIH-funded physician- scientist, he has dedicated his life to discovering new treatments and cures for deadly disorders like Castleman disease, which he was diagnosed with during medical school. He is in the top 1 percent youngest grant awardees of an R01, one of the most competitive and sought-after grants in all of biomedical research. Dr. Fajgenbaum has been recognized on the Forbes 30 Under 30 healthcare list, as a top healthcare leader by Becker's Hospital Review, and one of the youngest people ever elected as a Fellow of the College of Physicians of Philadelphia, the nation's oldest medical society. He was one of three recipients – including Vice President Joe Biden – of a 2016 Atlas Award from the World Affairs Council of Philadelphia. Order "Chasing My Cure" at bookstores nationwide or at http://www.chasingmycure.com/Business Leadership Series Intro and Outro music provided by Just Off Turner: https://music.apple.com/za/album/the-long-walk-back/268386576
Millions of dollars in federal grants have been terminated, throwing cutting-edge research at American universities into crisis. On this week's On the Media, meet the two men at the center of the fight over the future of academia.[0:00] Harvard president Alan Garber and National Institutes of Health director Jay Bhattacharya are at the heart of the national fight over the future of academia. Alan Garber has been cast as the defender of academic freedom and democracy; Jay Bhattacharya is Donald Trump's pick to lead the NIH, the agency withholding billions of dollars in research grants from Harvard. Oddly enough, the two men go way back: Garber was Bhattacharya's undergraduate thesis adviser and mentor in the late 1980s. This episode tells the story of how the two men found themselves adversaries — and what it means for the future of science. On the Media is supported by listeners like you. Support OTM by donating today (https://pledge.wnyc.org/support/otm). Follow our show on Instagram, Twitter and Facebook @onthemedia, and share your thoughts with us by emailing onthemedia@wnyc.org.
From STEM trailblazer to AI visionary, Dr. Tamara Nall shares her extraordinary journey of perseverance, innovation, and purpose-driven leadership, showing women what it truly means to build with legacy in mind.Growing up in Alabama and Georgia, Dr. Nall's parents instilled a belief that education is the one thing no one can take away. When an Emory University counselor told her that STEM “wasn't for women like her,” she didn't retreat, she rose higher, applying that very night to a dual-degree program with Georgia Tech. She went on to become the first business student to graduate from that demanding program, blending business acumen with computer science — a foundation that would power her future as a global entrepreneur and change-maker.That same determination has guided every step of her journey. From Harvard Business School to earning a doctorate in engineering and leading The Leading Niche, her award-winning systems integration firm serving agencies like the CDC, NIH, and VA. When told she'd lost a government contract for not having a PhD, Dr. Nall didn't internalize rejection; she transformed it into action, completing her doctorate during the pandemic while running her company full-time. Her story is one of relentless learning, courage, and redefining what's possible for women in technology and business.In our conversation, Dr. Nall opens up about scaling sustainably, leading with empathy, and why women-owned businesses must focus not only on passion but profitability. She shares insights on strategic networking, purpose-driven culture, and her bold ventures in AI, from her platform Reli AI to Human AI Nation, where she's exploring the evolving relationship between humans and technology. Through it all, her message is clear: innovation begins when you dare to claim the space others say you don't belong in.This episode is a masterclass in resilience, reinvention, and responsible leadership. Tune in to hear Dr. Tamara Nall's remarkable story and be inspired to build your own legacy of impact and innovation.Chapters
Why do we trust people who sound smart—even when they're not? Discover the psychology behind smooth talk and confident nonsense.This episode of An Ounce unpacks The Eloquence Illusion—how polished words and perfect delivery can disguise empty thinking. From corporate spin to “quantum detox,” we explore why we fall for what sounds right instead of what is right.Learn how to recognize verbal sleight-of-hand and keep your brain one step ahead of the charm.Like, subscribe, and share if this story surprised you.Related Episodes / Playlists:The Distasteful History of Toothpaste – how bad breath built a billion-dollar industry https://youtu.be/wq_H-8_pKKIWhy People Stopped Smiling in Photos – culture, cameras, and changing faces https://youtu.be/l3xddLnkqME
Priscilla Chan and Mark Zuckerberg join a16z's Ben Horowitz, Erik Torenberg, and Vineeta Agarwala to share how the Chan Zuckerberg Initiative is building the computational tools that will accelerate the cure, prevention, and management of all disease by century's end. They explain why basic science needs $100 million-scale projects that traditional NIH grants can't fund, how their Cell Atlas became biology's missing periodic table with millions of cells catalogued in open-source format, and why their new virtual cell models will let scientists test high-risk hypotheses in silico before investing in expensive wet lab work. Plus: the organizational shift unifying the Biohub under AI leadership, what happens when biologists and engineers sit side-by-side, and why modern biology labs are expanding compute instead of square footage. Timestamps:4:17 - Building tools to accelerate scientific discovery5:47 - The credible path to funding basic science7:21 - Biohub = Frontier Biology + Frontier AI9:05 - Challenges building on a 10-15 year timeline9:43 - How CZI chooses what to work on11:15 - Making sense of science with LLMs11:31 - Measuring success in the therapeutic realm13:32 - “Most diseases should be thought of as rare diseases”15:39 - Inspiration: building a periodic table for biology19:27 - Why virtual cells?21:17 - The Biohub Master Plan21:51 - How virtual cell models allow more risk taking28:15 - Bringing CZI & Biohub together30:32 - Why Biohub matters33:36 - The importance of interface design in democratizing scientific discovery35:34 - How Biohub encourages cross-functional collaboration40:38 - Looking ahead: the broader impact of AI on biotech Stay Updated: If you enjoyed this episode, be sure to like, subscribe, and share with your friends!Find a16z on X: https://x.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zListen to the a16z Podcast on Spotify: https://open.spotify.com/show/5bC65RDvs3oxnLyqqvkUYXListen to the a16z Podcast on Apple Podcasts: https://podcasts.apple.com/us/podcast/a16z-podcast/id842818711Follow our host: https://x.com/eriktorenbergPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Stay Updated:Find a16z on XFind a16z on LinkedInListen to the a16z Podcast on SpotifyListen to the a16z Podcast on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
On this episode of MaternalRx on the Pharmacy Podcast Network, host Dr. Danielle Raiman Plummer, PharmD, consulting pharmacist, sits down with Mary Kucek, PMP, and Dr. Devin Bustin, MD, co-founders of OvaryIt, creators of the PRISM EHR platform and the OvaryIt Foundation for survivors of domestic abuse and human trafficking. Mary shares her powerful and life-threatening experience with a telemedicine platform that failed to follow contraceptive safety guidelines, an event that changed the course of her career and mission. Together, Mary and Dr. Bustin explain how their NIH-funded research led to the creation of OvaryIt and PRISM: an innovative, pharmacist-centered platform that bridges the safety of in-person care with the accessibility of telehealth. Tune in to hear how retail pharmacists can now lead the next evolution in family planning access, overcoming the barriers to scaling these services, and how technology and policy can empower safer, more equitable reproductive care for all. “Prism will help retail pharmacies become public health access points for central health services.”
Administrative Law: May the NIH cap "indirect costs" paid from federal research grants? - Argued: Wed, 05 Nov 2025 11:28:9 EDT
In this inspiring episode of Moving Medicine Forward,Amanda King, Senior Clinical Scientist at CTI, discusses her remarkable journey from pediatric ICU nurse practitioner to leading-edge oncology researcher. Amanda shares how personal loss fueled her passion for patient-centered careand clinical research, and how her work at the NIH and CTI is shaping the future of medicine. From the complexities of oncology trials to the emotional weight of working with vulnerable patients, Amanda offers a candid look at thechallenges and triumphs of advancing therapeutic options. Whether you're in healthcare or simply curious about the human stories behind medical innovation, this episode is a must-listen.00:30 Meet Amanda King: her background and passionfor patient-centered care. 01:07 Amanda's clinical roots in pediatric ICU andtransition to research. 02:00 Pursuing a PhD and discovering a love forclinical trials at the NIH. 02:34 The motivation behind Amanda's shift toclinical research. 03:34 Why Amanda joined CTI and what drew her toindustry research. 05:10 Amanda's role as a Senior Clinical Scientistand her impact on trial safety. 06:35 Deep dive into Amanda's work at the NIH and theimportance of patient outcomes data. 09:21 Challenges in oncology trials: balancingsafety, complexity, and emotional toll. 11:39 The rewards of working in oncology and Amanda'spersonal connection to cancer research. 13:08 Advice for young people interested in clinicalresearch and the importance of mentorship. 15:14 Amanda's vision for the future of medicine:innovation meets compassion. 16:10 Closing thoughts and how to stay connected withCTI.
Two-time Emmy and three-time NAACP Image Award-winning television Executive Producer Rushion McDonald interviewed Dr. Schenta D. Randolph.
Two-time Emmy and three-time NAACP Image Award-winning television Executive Producer Rushion McDonald interviewed Dr. Schenta D. Randolph.
Two-time Emmy and three-time NAACP Image Award-winning television Executive Producer Rushion McDonald interviewed Dr. Schenta D. Randolph.
Milk has long been sold as the key to strong bones, but research challenges that claim: many people don't tolerate dairy, calcium needs are lower than advertised, and higher milk intake doesn't necessarily prevent fractures. Politics and industry marketing helped set “three glasses a day,” even though healthy bones depend more on overall diet and lifestyle—things like vitamin D, movement, and avoiding soda, excess sugar, and stress that drive calcium loss. Dairy may be helpful for some diets, but it can also trigger bloating, acne, congestion, or digestive issues. The good news is that strong bones and good nutrition are still very doable without cow's milk—think leafy greens, sardines, almonds, chia, and sunshine for vitamin D. In this episode, I discuss, along with Dr. David Ludwig and Dr. Elizabeth Boham why bone health depends more on diet, lifestyle, and nutrient balance than on dairy. David S. Ludwig, MD, PhD, is an endocrinologist and researcher at Boston Children's Hospital, Professor of Pediatrics at Harvard Medical School, and Professor of Nutrition at the Harvard T.H. Chan School of Public Health. He co-directs the New Balance Foundation Obesity Prevention Center and founded the Optimal Weight for Life (OWL) program, one of the nation's largest clinics for children with obesity. For over 25 years, Dr. Ludwig has studied how diet composition affects metabolism, body weight, and chronic disease risk, focusing on low glycemic index, low-carbohydrate, and ketogenic diets. Called an “obesity warrior” by Time Magazine, he has championed policy changes to improve the food environment. A Principal Investigator on numerous NIH and philanthropic grants, Dr. Ludwig has published over 200 scientific articles and three books for the public, including the #1 New York Times bestseller Always, Hungry? Dr. Elizabeth Boham is Board Certified in Family Medicine from Albany Medical School, and she is an Institute for Functional Medicine Certified Practitioner and the Medical Director of The UltraWellness Center. Dr. Boham lectures on a variety of topics, including Women's Health and Breast Cancer Prevention, insulin resistance, heart health, weight control and allergies. She is on the faculty for the Institute for Functional Medicine. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN to save 15%. Full-length episodes can be found here:Why Most Everything We Were Told About Dairy Is Wrong Is It Okay To Eat Cheese And What Types Of Dairy Should You Avoid? Is Lactose Intolerance Causing Your Gut Issues?
“I couldn't agree with Dr. Drew more!” writes FL Surgeon General Dr. Joseph Ladapo. “Many countries don't have vaccine mandates at all, but through education achieve comparable vaccination rates.” Dr. Ladapo is pushing to end all vaccine mandates for children, calling them unethical and a violation of parents' rights. In an interview with BlazeTV's Sara Gonzales, Ladapo argued that the government should not control what goes into a person's body, describing the issue as both moral and constitutional. He says the state's goal is to restore parents' freedom to make medical decisions for their children. Dr. Joseph A. Ladapo is the Surgeon General of Florida and Professor of Medicine at the University of Florida. His research focuses on behavioral economic strategies to reduce cardiovascular risk among disadvantaged populations and has been supported by the NIH and the Robert Wood Johnson Foundation. He is a Harvard-trained physician and health policy expert. Follow at https://x.com/FLSurgeonGen⠀Dr. Scott Jensen is a family physician, former Minnesota State Senator, and currently a candidate for Minnesota Governor. He advocates for health freedom and patient choice. Learn more at https://drscottjensen.com⠀Jay Pea is the president of Save Standard Time, a nonprofit advocating for better health and safety through alignment of clocks with the sun. He has testified in two dozen capitals and written op-eds in major outlets like The Hill. Learn more at https://savestandardtime.com 「 SUPPORT OUR SPONSORS 」 Find out more about the brands that make this show possible and get special discounts on Dr. Drew's favorite products at https://drdrew.com/sponsors • FATTY15 – The future of essential fatty acids is here! Strengthen your cells against age-related breakdown with Fatty15. Get 15% off a 90-day Starter Kit Subscription at https://drdrew.com/fatty15 • PALEOVALLEY - "Paleovalley has a wide variety of extraordinary products that are both healthful and delicious,” says Dr. Drew. "I am a huge fan of this brand and know you'll love it too!” Get 15% off your first order at https://drdrew.com/paleovalley • VSHREDMD – Formulated by Dr. Drew: The Science of Cellular Health + World-Class Training Programs, Premium Content, and 1-1 Training with Certified V Shred Coaches! More at https://drdrew.com/vshredmd • THE WELLNESS COMPANY - Counteract harmful spike proteins with TWC's Signature Series Spike Support Formula containing nattokinase and selenium. Learn more about TWC's supplements at https://twc.health/drew 「 MEDICAL NOTE 」 Portions of this program may examine countervailing views on important medical issues. Always consult your physician before making any decisions about your health. 「 ABOUT THE SHOW 」 Ask Dr. Drew is produced by Kaleb Nation (https://kalebnation.com) and Susan Pinsky (https://twitter.com/firstladyoflove). This show is for entertainment and/or informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment. Executive Producers • Kaleb Nation - https://kalebnation.com • Susan Pinsky - https://x.com/firstladyoflove Content Producer & Booking • Emily Barsh - https://x.com/emilytvproducer Hosted By • Dr. Drew Pinsky - https://x.com/drdrew Learn more about your ad choices. Visit megaphone.fm/adchoices
The Harvard Plan - our collaboration with the Boston Globe, is back! In episode one, we hear what unfolded at Harvard from Donald Trump's inauguration to convocation 2025. Three main characters, inside Harvard, tell the story from their perspective: politics professor Ryan Enos, genetics professor and cancer researcher Kamila Naxerova and campus conservative Kit Parker, lieutenant colonel in the United States Army Reserve and Professor of Bioengineering and Applied Physics at Harvard. The personal perspectives of our three guides are interwoven with the dramatic timeline and unfolding news. On the Media is supported by listeners like you. Support OTM by donating today (https://pledge.wnyc.org/support/otm). Follow our show on Instagram, Twitter and Facebook @onthemedia, and share your thoughts with us by emailing onthemedia@wnyc.org.