Podcast appearances and mentions of victor nizet

Antibiotic resistant bacteria are threatening modern society by making antibiotics obsolete. Dr. Nizet is a Professor and Vice Chair in the Department of Pediatrics at UCSD, as well as the faculty lead for the UCSD Collaborative to Halt Antibiotic-Resistant Microbes (CHARM). His laboratory studies how the human immune system interacts with microbial pathogens, with particular focus on antibiotic resistant bacteria and how to treat them. Dr. Nizet discusses how his training as a physician helps drive the research in his laboratory, how repurposing therapeutic drugs could help fight antimicrobial resistance, how taking advantage of host immune responses can enhance the treatment of infectious diseases, how the success of modern medicine is training some bacteria to become pathogenic, how nanobots made from algae can be used to treat difficult infections, and how the environment at UC San Diego contributed to the success of his lab. This episode was supported by the do-it-yourself mail-order Gram stain kit.* Participants: Karl Klose, Ph.D. (UTSA) Victor Nizet, M.D. (UC San Diego) Venus Stanton (UTSA) Jesus Romo, Ph.D. (UTSA) * "Ads" heard on microTalk are for parody purposes only, there are no actual products for sale.

SpaceX Explosion Damages Environment Around Launch Site Last Thursday, SpaceX's South Texas facility was awash in noise and fire, as crowds gathered in South Padre Island and Port Isabel to watch Starship's first orbital launch. It was the largest and most powerful rocket ever made, standing at around 400 feet tall. Four minutes into the launch, SpaceX detonated the rocket after the SuperHeavy booster failed to separate from the Starship as planned. The launch destroyed the company's launch pad, spreading concrete up to three quarters of a mile away. Cameras left by YouTubers were either knocked down or destroyed in the rumble, along with some of the fence surrounding the launch pad's road-facing property. To read the rest, visit sciencefriday.com.   The Private Space Race Takes A Toll On Planet Earth After the SpaceX explosion last month, debris wasn't the only thing on the minds of Science Friday listeners. The following messages arrived in our inbox after we reported on 3-D printed rockets in March. It was interesting to hear you discuss 7 space launches in 5 days, and then just moments later the fact that we're not on track to reduce carbon emissions. My understanding is that rocket launches release huge amounts of carbon and other greenhouse gases. Story idea?—@RevBobIerien, Twitter Also regarding the 3-D rockets there wasn't any concern made for space pollution was there? I may have tuned out unhappily before the end. —Juanita H, email How much carbon do rockets contribute to global warming? —Robert C, email Very disappointing to hear the report of new “cheaper” 3D-printed rockets are available so that, like fast food pods and big gulps, we can now drop even more cheap **** into the ocean. And, *immediately* following a story about the new report on climate change, what exactly is the carbon footprint resulting from the ability of more people to more cheaply fire rockets into space? —David M, email Carbon isn't the big pollutant that comes from spaceflight, says Dr. Eloise Marais, associate professor in physical geography at University College London. Instead, black carbon or soot particles are generated and released directly into the atmosphere, alongside reactive nitrogen and nitrogen oxides. Dr. Marais joins Ira to talk about how much of an impact increased rocket launches could have on the atmosphere, and how that compares to the auto industry.    How To Combat The Antibiotic Resistance Crisis For years scientists have been ringing alarm bells about a global antibiotic resistance crisis. Now hospitals and healthcare facilities face the consequences: In the United States, there are 2.8 million antimicrobial-resistant infections every year, and more than 35,000 people die from these infections. Bacteria naturally try to outsmart the drugs designed to kill them, which causes treatments to become ineffective over time. While new antibiotics are made to respond to these resistant strains, the bacteria continue to evolve—creating a constant, and costly, cycle. There's a number of added factors driving the crisis, including antibiotic use in livestock and the general overprescription of antibiotics. About 1 in 3 antibiotic prescriptions in outpatient settings like urgent care or emergency departments are unnecessary. Scientists are struggling to keep up with the need to replace antibiotics that no longer work. It's a never ending game of catch up. Ira discusses some of the possible solutions to this vexing problem and takes listener questions with Dr. Victor Nizet, faculty lead of the Collaborative to Halt Antibiotic-Resistant Microbes at the University of California San Diego and Dr. Eddie Stenehjem, executive vice chair of medicine at the University of Colorado.   Are Phages A New Page In Medicine? One of the many possible solutions to the global antibiotic resistance crisis is an old idea that's new again—bacteriophages, or phages for short. Phages are viruses that exist solely to kill bacteria and are abundant in nature. While scientists first discovered phages' ability to treat bacterial infections about a century ago, there's been little interest in turning them into a treatment for patients with antibiotic resistant infections—until recently. Ira talks with Dr. Graham Hatfull, professor of biotechnology at the University of Pittsburgh about the latest in phage science.   Transcripts for each segment will be available the week after the show airs on sciencefriday.com.

In this episode, Kellen interviews Dr. Victor Nizet, a distinguished professor of pediatrics and pharmaceutical sciences at UCSD and the vice chair of basic research in the department of pediatrics at UCSD. Kellen and Victor discuss one of the Nizet lab's recent publications (led by Josh Sun, Pharm.D. Ph.D.) identifying novel treatment strategies for Staph aureus-induced sepsis. Kellen and Victor also talk about Victor's career path and scientific philosophies. S. aureus-induced sepsis paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9121309/ Nizet lab website: http://nizetlab.ucsd.edu/ Victor's Twitter handle: @victornizet Thank you to our sponsors, NCI & CCMI! Please take a few minutes to write us a review wherever you listened to this podcast—it will help us communicate great science. Finally, we would love to hear from you. Please send any questions or comments to @KellenCavagnero on Twitter.

The rise in antibiotic resistance poses one of the greatest challenges to public health and modern medicine. The roots of the dilemma are many - overzealous use of antibiotics clinical and agricultural settings, the departure of major pharmaceutical companies from antibiotic development ,and simple Darwinian evolution of microbes. Can we lift ourselves out of the hole that we have dug? Many ethical dilemmas must be acknowledged and confronted, such as balancing restrictions on individual liberty for the protection of the public health and the well being of future generations. We must also consider just and sustainable use of this precious resource tailored to the markedly differing economic and epidemiological situations across the globe with diverse health systems and variable antibiotic markets. Victor Nizet, MD describes the current challenges and potential paths forward. Series: "Exploring Ethics" [Health and Medicine] [Show ID: 36634]

The rise in antibiotic resistance poses one of the greatest challenges to public health and modern medicine. The roots of the dilemma are many - overzealous use of antibiotics clinical and agricultural settings, the departure of major pharmaceutical companies from antibiotic development ,and simple Darwinian evolution of microbes. Can we lift ourselves out of the hole that we have dug? Many ethical dilemmas must be acknowledged and confronted, such as balancing restrictions on individual liberty for the protection of the public health and the well being of future generations. We must also consider just and sustainable use of this precious resource tailored to the markedly differing economic and epidemiological situations across the globe with diverse health systems and variable antibiotic markets. Victor Nizet, MD describes the current challenges and potential paths forward. Series: "Exploring Ethics" [Health and Medicine] [Show ID: 36634]

The rise in antibiotic resistance poses one of the greatest challenges to public health and modern medicine. The roots of the dilemma are many - overzealous use of antibiotics clinical and agricultural settings, the departure of major pharmaceutical companies from antibiotic development ,and simple Darwinian evolution of microbes. Can we lift ourselves out of the hole that we have dug? Many ethical dilemmas must be acknowledged and confronted, such as balancing restrictions on individual liberty for the protection of the public health and the well being of future generations. We must also consider just and sustainable use of this precious resource tailored to the markedly differing economic and epidemiological situations across the globe with diverse health systems and variable antibiotic markets. Victor Nizet, MD describes the current challenges and potential paths forward. Series: "Exploring Ethics" [Health and Medicine] [Show ID: 36634]

The rise in antibiotic resistance poses one of the greatest challenges to public health and modern medicine. The roots of the dilemma are many - overzealous use of antibiotics clinical and agricultural settings, the departure of major pharmaceutical companies from antibiotic development ,and simple Darwinian evolution of microbes. Can we lift ourselves out of the hole that we have dug? Many ethical dilemmas must be acknowledged and confronted, such as balancing restrictions on individual liberty for the protection of the public health and the well being of future generations. We must also consider just and sustainable use of this precious resource tailored to the markedly differing economic and epidemiological situations across the globe with diverse health systems and variable antibiotic markets. Victor Nizet, MD describes the current challenges and potential paths forward. Series: "Exploring Ethics" [Health and Medicine] [Show ID: 36634]

The rise in antibiotic resistance poses one of the greatest challenges to public health and modern medicine. The roots of the dilemma are many - overzealous use of antibiotics clinical and agricultural settings, the departure of major pharmaceutical companies from antibiotic development ,and simple Darwinian evolution of microbes. Can we lift ourselves out of the hole that we have dug? Many ethical dilemmas must be acknowledged and confronted, such as balancing restrictions on individual liberty for the protection of the public health and the well being of future generations. We must also consider just and sustainable use of this precious resource tailored to the markedly differing economic and epidemiological situations across the globe with diverse health systems and variable antibiotic markets. Victor Nizet, MD describes the current challenges and potential paths forward. Series: "Exploring Ethics" [Health and Medicine] [Show ID: 36634]

The rise in antibiotic resistance poses one of the greatest challenges to public health and modern medicine. The roots of the dilemma are many - overzealous use of antibiotics clinical and agricultural settings, the departure of major pharmaceutical companies from antibiotic development ,and simple Darwinian evolution of microbes. Can we lift ourselves out of the hole that we have dug? Many ethical dilemmas must be acknowledged and confronted, such as balancing restrictions on individual liberty for the protection of the public health and the well being of future generations. We must also consider just and sustainable use of this precious resource tailored to the markedly differing economic and epidemiological situations across the globe with diverse health systems and variable antibiotic markets. Victor Nizet, MD describes the current challenges and potential paths forward. Series: "Exploring Ethics" [Health and Medicine] [Show ID: 36634]

The rise in antibiotic resistance poses one of the greatest challenges to public health and modern medicine. The roots of the dilemma are many - overzealous use of antibiotics clinical and agricultural settings, the departure of major pharmaceutical companies from antibiotic development ,and simple Darwinian evolution of microbes. Can we lift ourselves out of the hole that we have dug? Many ethical dilemmas must be acknowledged and confronted, such as balancing restrictions on individual liberty for the protection of the public health and the well being of future generations. We must also consider just and sustainable use of this precious resource tailored to the markedly differing economic and epidemiological situations across the globe with diverse health systems and variable antibiotic markets. Victor Nizet, MD describes the current challenges and potential paths forward. Series: "Exploring Ethics" [Health and Medicine] [Show ID: 36634]

The rise in antibiotic resistance poses one of the greatest challenges to public health and modern medicine. The roots of the dilemma are many - overzealous use of antibiotics clinical and agricultural settings, the departure of major pharmaceutical companies from antibiotic development ,and simple Darwinian evolution of microbes. Can we lift ourselves out of the hole that we have dug? Many ethical dilemmas must be acknowledged and confronted, such as balancing restrictions on individual liberty for the protection of the public health and the well being of future generations. We must also consider just and sustainable use of this precious resource tailored to the markedly differing economic and epidemiological situations across the globe with diverse health systems and variable antibiotic markets. Victor Nizet, MD describes the current challenges and potential paths forward. Series: "Exploring Ethics" [Health and Medicine] [Show ID: 36634]

Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence viaa multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the humanhost populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35844]

Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence viaa multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the humanhost populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35844]

Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence viaa multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the humanhost populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35844]

Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence viaa multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the humanhost populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35844]

Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence viaa multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the humanhost populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35844]

Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence viaa multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the humanhost populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35844]

Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence viaa multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the humanhost populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35844]

Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence viaa multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the humanhost populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35844]

Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence viaa multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the humanhost populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35844]

Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence viaa multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the humanhost populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35844]

Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence viaa multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the humanhost populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35844]

Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence viaa multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the humanhost populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35844]

Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence viaa multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the humanhost populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35844]

Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence viaa multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the humanhost populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35844]

Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence viaa multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the humanhost populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35844]

Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence viaa multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the humanhost populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35844]

Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence viaa multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the humanhost populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35844]

Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence viaa multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the humanhost populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35844]

Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence viaa multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the humanhost populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35844]

Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence viaa multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the humanhost populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35844]

Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence viaa multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the humanhost populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35844]

Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence viaa multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the humanhost populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35844]

On our current trajectory, 300 million excess deaths will occur due to antibiotic resistance to by 2050. What can be done change our path and stop superbugs in their tracks? Victor Nizet, MD discusses the roots and scope of the problem as well as novel solutions. Series: "Exploring Ethics" [Health and Medicine] [Show ID: 31545]

On our current trajectory, 300 million excess deaths will occur due to antibiotic resistance to by 2050. What can be done change our path and stop superbugs in their tracks? Victor Nizet, MD discusses the roots and scope of the problem as well as novel solutions. Series: "Exploring Ethics" [Health and Medicine] [Show ID: 31545]

On our current trajectory, 300 million excess deaths will occur due to antibiotic resistance to by 2050. What can be done change our path and stop superbugs in their tracks? Victor Nizet, MD discusses the roots and scope of the problem as well as novel solutions. Series: "Exploring Ethics" [Health and Medicine] [Show ID: 31545]

On our current trajectory, 300 million excess deaths will occur due to antibiotic resistance to by 2050. What can be done change our path and stop superbugs in their tracks? Victor Nizet, MD discusses the roots and scope of the problem as well as novel solutions. Series: "Exploring Ethics" [Health and Medicine] [Show ID: 31545]