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Latest episodes from Health and Medicine (Video)

Becoming a Perinatologist: One Doctor's Path

Play Episode Listen Later Sep 26, 2026 20:30


Gladys (Sandy) Ramos, M.D., is a UC San Diego Health perinatologist and professor who cares for patients with complex pregnancies, including those affected by diabetes. She explains how immigrating from Peru, learning from her grandmother and wanting to serve Spanish-speaking communities shaped her work. Ramos also describes feeling out of place in college and not getting into medical school on her first attempt. Research, mentors, supportive peers and a UC Irvine medical school preparation program helped her strengthen her skills and confidence. Today, she uses her bilingual skills and cultural knowledge to build trust, discuss nutrition and health beliefs, and help patients work toward safe pregnancies and healthy babies. Her experience also shapes the guidance she gives students pursuing medicine. Series: "Education Channel" [Health and Medicine] [Education] [Show ID: 41599]

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How Startups are Accelerating Innovation in Women's Health

Play Episode Listen Later Sep 26, 2026 46:40


Vaginal microbiome research may offer new ways to understand infections, fertility, preterm birth and other areas of women's health. Pita Navarro, co-founder and chief scientific officer of Evvy, joins Cynthia Gyamfi-Bannerman, M.D., M.S., of UC San Diego Health, to explain how patient-contributed samples and health information can support research and product development. Navarro describes Evvy's direct-to-consumer testing model, its work to build a large metagenomic data set and the importance of distinguishing established findings from emerging evidence. She also discusses clinical validation, patient trust, academic partnerships and the challenges of bringing scientific discoveries into everyday care. Their conversation shows why successful health startups need more than promising science: they must solve meaningful problems, fit real-world workflows and stay close to the patients they aim to serve. Series: "UC San Diego Women's Health Symposium" [Health and Medicine] [Show ID: 41657]

Transforming Brain Health

Play Episode Listen Later Sep 22, 2026 1:02


More than 7 million Americans are living with Alzheimer's, according to the Alzheimer's Association. UC Davis researcher Alyssa Weakley is working on I-Care, a new technology that's helping Alzheimer's patients live longer in their own homes. At UC Davis, our researchers are working to better understand the causes of dementia, including Alzheimer's, its most common form, while advancing understanding and improving care for those affected. Through innovative studies, we're paving the way for new treatments and strategies to slow, prevent and ultimately transform how we approach these complex neurological conditions. Series: "UC Davis News" [Health and Medicine] [Show ID: 41737]

Social Isolation is a Biological Risk Factor in Recovery after Maternal Birth Injury with Dr. Lindsey Burnett

Play Episode Listen Later Sep 19, 2026 10:40


Social isolation may influence how the body recovers from pelvic floor injury after childbirth. Lindsay Burnett, M.D., Ph.D., assistant professor and physician-scientist at UC San Diego, studies factors during pregnancy and postpartum that may affect pelvic floor muscle recovery, including medications, diet, exercise and social interaction. Her research grew from clinical observations connecting patients' perceptions of traumatic births with physical outcomes such as fecal incontinence. In a preclinical model, social support was associated with improved pelvic floor muscle regeneration and distinct metabolic changes. Burnett is investigating metabolites involved in wound healing and skeletal muscle regeneration, along with possible connections between social interaction, the gut microbiome and systemic metabolism. The research offers a biological perspective on why emotional and social support may matter during postpartum recovery. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41640]

Mechanosensory Control of Pregnancy and Parturition

Play Episode Listen Later Sep 15, 2026 14:53


Mechanical forces may help the body coordinate pregnancy and labor. Yunxiao Zhang, Ph.D., of Scripps Research Institute, examines how PIEZO1 and PIEZO2, proteins that open in response to stretch, contribute to uterine contractions and the timing of birth. Zhang finds PIEZO1 in uterine smooth muscle and PIEZO2 in sensory nerve fibers around the cervix. In mouse models, removing both channels weakens labor contractions, delays the start of delivery and increases the time between pups. The findings suggest that PIEZO1 helps prepare uterine muscle for stronger contractions, while PIEZO2 helps sensory nerves detect cervical stretch. Zhang also discusses how fats in cell membranes may change PIEZO1 sensitivity and why uterine cells and sensory nerves have connected roles. This research offers a new way to study how physical forces help regulate labor. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41642]

Funding Enables Life-Changing Prosthetics

Play Episode Listen Later Sep 14, 2026 1:11


David Brockman suffered a traumatic accident in 2019 that led to the amputation of his hand from the wrist down. Following his surgery at the UC Davis Medical Center, he was connected with engineering professor Jonathon Schofield, who collaborates with Ph.D. students on prosthetic technology. Through federally funded research projects, these students were able to design and provide Brockman with a custom myoelectric hand —a prosthetic he can control electronically. He emphasizes that without federal funding, schools and researchers wouldn't have the resources to develop these innovations. "My hand prosthetic would not have been available to me without funding.Without that money, these schools can't do that and give people a chance to see what is possible.” — David Brockman Series: "UC Davis News" [Public Affairs] [Health and Medicine] [Show ID: 41733]

Finding a Cure for Cats With Coronavirus

Play Episode Listen Later Sep 14, 2026 1:08


Feline infectious peritonitis, a form of coronavirus, is almost 100% deadly for cats. Through a federally funded trial, UC Davis researchers found a cure for FIP and the treatment for cats could be used in the future to treat humans with long COVID. Series: "UC Davis News" [Health and Medicine] [Show ID: 41740]

What is Valley Fever?

Play Episode Listen Later Sep 14, 2026 2:23


Valley fever, also known as coccidioidomycosis, is a fungal infection that is contracted when soil borne spores are disrupted and inhaled. The infections can cause symptoms similar to pneumonia or COVID-19, such as cough, headache, fever and, in more severe cases, meningitis. UC Davis Health patient Rex shares his journey with valley fever and how UC Davis doctors and researchers are advancing earlier diagnosis and better treatments through clinical care and laboratory science. Series: "UC Davis News" [Health and Medicine] [Science] [Agriculture] [Show ID: 41743]

Behind the Technology That Allowed a Man With ALS to 'Speak' Again

Play Episode Listen Later Sep 8, 2026 5:50


Chancellor May stops by the UC Davis Neuroprosthetics Lab to meet the researchers behind brain-computer interface technology. The technology helped a man with ALS communicate again with his family and used AI to mimic the sound of his own voice. Watch as Chancellor May tries out the technology himself in a lab simulation. Series: "UC Davis News" [Health and Medicine] [Science] [Show ID: 41741]

Creating the UC Menopause Collaborative: An Opportunity for Research and Clinical Collaboration

Play Episode Listen Later Sep 4, 2026 38:21


Menopause care is changing as more patients seek evidence-based guidance for symptoms, prevention, and long-term health. Kathryn Macaulay, M.D., M.S.C.P., F.A.C.O.G., UC San Diego Health, and Rajita Patil, M.D., M.S.C.P., F.A.C.O.G., UCLA Health, explain why many people still struggle to find trained care, even as menopause affects sleep, mood, work, genitourinary health, and cardiometabolic risk. They connect hormone therapy history with today's demand for reliable, individualized options, including non-hormonal approaches, and outline the UC Menopause Collaborative's work to expand training, standardize work flows, support flexible care models, and build research-ready data across UC health centers. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41634]

Multidisciplinary Care of Pregnant Women with Cardiovascular Disease with Dr. Laith Alshawabkeh

Play Episode Listen Later Aug 25, 2026 6:09


Cardiovascular disease is a major threat to maternal health during pregnancy and the peripartum period, particularly for women with preexisting heart conditions. A UC San Diego cardiologist describes the development of a multidisciplinary cardio-obstetrics initiative designed to coordinate care for patients with congenital heart disease, heart failure, arrhythmias and coronary artery disease. The program brings cardiology and maternal-fetal medicine together with other specialties to establish consistent protocols, improve maternal and fetal outcomes, advance research and train future clinicians. As more people born with congenital heart disease survive into adulthood and consider pregnancy, the need for this specialized care continues to grow. Longitudinal surveillance is also helping researchers study outcomes and identify opportunities for better monitoring. Coordinated cardio-obstetrics care can help manage complex cardiovascular risks throughout pregnancy and delivery. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41641]

Label-free AI-enabled Imaging Flow Cytometry for Discovery of Subpopulations of Extravillous Trophoblast from a Stem Cell-based Model of Trophoblast Differentiation

Play Episode Listen Later Aug 21, 2026 32:21


AI-powered cell imaging may help researchers identify biological differences that are difficult or impossible to see by eye. Yu-Hwa Lo, Ph.D., and Louise Laurent, M.D., Ph.D., describe a system that combines high-speed imaging, cell sorting, microfluidics, and artificial intelligence. The technology creates label-free images of cells, uses AI to classify them, and can isolate selected cells for deeper molecular analysis. Laurent explains how the team is applying the system to human trophoblast stem cells, which give rise to specialized placental cells involved in nutrient transport, hormone production, blood vessel remodeling, and immune regulation. Lo describes how AI can distinguish cell populations and identify features that may not be apparent to human observers. The researchers ultimately hope to connect imaging features with gene expression, proteins, and metabolism, allowing cell characteristics and behavior to be predicted from images alone. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41637]

DM in Pregnancy and AI - Ben Smarr Ph.D. and Sandy Ramos M.D.

Play Episode Listen Later Aug 18, 2026 29:00


Continuous glucose monitoring and wearable data are changing how researchers study pregnancy and women's health. Gladys (Sandy) Ramos, M.D., explains why glucose control is difficult during pregnancy and how CGM can reveal patterns that finger-stick testing may miss. She also describes research on CGM use in type 2 and gestational diabetes, labor, and behavior change. Ben Smarr, Ph.D., shows how wearable data can track changes in temperature, heart rate, activity, respiration, menstrual cycles, pregnancy, and aging. Together, the speakers discuss personalized care, participant engagement, patient-driven innovation, and access to these tools. The goal is to learn from continuous data while recognizing limits in evidence, interpretation, and equity. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41636]

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Hall of Famer David Justice on Prostate Cancer

Play Episode Listen Later Aug 14, 2026 31:59


For people diagnosed with cancer, patient advocacy can play a vital role throughout the treatment process. At UC San Diego's annual Prostate Cancer Patient Summit, keynote speaker and three-time MLB All-Star David Justice brought visibility and purpose to that message, underscoring the broad reach and lasting importance of speaking up for patients and families. [Health and Medicine] [Show ID: 41648]

Improving Early Alzheimers Detection in Women by Integrating Multimodal Data Into Clinical Decision Tools with Iris Broce-Diaz Ph.D.

Play Episode Listen Later Aug 6, 2026 13:36


Alzheimer's disease can begin developing years before memory and thinking problems become noticeable. Iris Broce-Diaz, Ph.D., of UC San Diego is developing accessible, noninvasive, and cost-effective tools to help primary care physicians and neurologists identify people at higher risk earlier. Her models combine information from cognitive assessments, brain imaging, genetics, and PET scans to estimate the likelihood that mild cognitive impairment will progress within five years. Combining multiple measures improves the models' ability to separate higher- and lower-risk patients. Broce-Diaz also plans to add women-specific factors, including menopause history, hormone therapy, reproductive history, endocrine markers, and symptoms. The goal is to support better referrals, guide monitoring, and help eligible patients consider treatment sooner. Earlier risk assessment could also strengthen clinical trials and make dementia care more useful across different health systems. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41632]

Development of a Non-Invasive Male Fertility Assay for Testicular Sperm Retrieval and Fertility Treatment with Kun Tan Ph.D.

Play Episode Listen Later Aug 3, 2026 9:45


Men with non-obstructive azoospermia may undergo microscopic testicular sperm extraction, or mTESE, without knowing whether sperm will be found. Kun Tan, Ph.D., of UC San Diego explains how molecular semen analysis could provide a noninvasive way to predict the procedure's outcome. The assay uses stage-specific germ cell markers identified through single-cell RNA sequencing, then measures those markers in semen with qPCR. Because semen contains germ cells from different stages of sperm development, their molecular signals may reflect what is happening inside the testes. Tan shows how the assay predicts whether sperm retrieval was successful and can identify where sperm development may be blocked. The research could help couples planning IVF or ICSI avoid unnecessary surgery, reduce financial and emotional burdens, and receive more detailed information about male infertility before treatment. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41630]

Motivating Movement: An Age-Friendly Approach to Pain Mood and Mobility

Play Episode Listen Later Jul 29, 2026 48:20


Chronic pain in older adults can affect mobility, mood, sleep, social connection, and independence. Una Makris, M.D., M.Sc., UC San Diego and VA San Diego Healthcare System, explains why musculoskeletal pain is common later in life and why medications or procedures alone may not meet the needs of many patients. Drawing on her work in rheumatology and geriatrics, Makris describes how pain and depression can reinforce each other, making it important to address both together. She highlights an age-friendly behavioral coaching approach that uses motivational interviewing, values-based goal setting, physical activity, and social support to help people reconnect with meaningful activities. By focusing on small, safe increases in movement, this research points to practical ways to support better function, quality of life, and healthy aging. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41172]

Accessible Theater: Disability Center Stage

Play Episode Listen Later Jul 28, 2026 40:12


As part of the 2026 Developmental Disabilities Conference, Corinne Melon, Managing Director, Phamaly Theatre Company, talks about accessible theater for people with disabilities. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 41468]

Pain Assessment and Management for Children and Adults with Developmental Disabilities

Play Episode Listen Later Jul 28, 2026 40:54


As part of the 2026 Developmental Disabilities Conference, Chantel Burkitt, Senior Clinical Scientist, and Todd Dalberg, Pediatrician and Palliative Medicine Physician, Gilette Children's Hospital, discuss how to assess and manage pain for people with developmental disabilities. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 41471]

The Rescue: Centering Autistic Voices in Film

Play Episode Listen Later Jul 25, 2026 36:22


Authentic autism representation begins with listening to autistic people and including them in stories about their lives. Seth Bakke, producer, writer and director of The Rescue, explains how his autistic cousin Aaron and a poem by autistic typer Peter Tran inspired the film. Bakke describes working with Aaron on screen, consulting the Tran family and adapting the set to support his needs. Autistic typers Otto Lana and Peter Tran, joined by Steven Tran, a postdoctoral researcher at UC San Diego, discuss where the film reflects their experiences, where it simplifies communication through typing and why creative freedom must remain grounded in lived experience. They address presuming competence, the difference between hearing and listening, and the need for autistic actors and advisers. Their participation challenges stereotypes and helps audiences see they should be full participants in their own stories. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Arts and Music] [Show ID: 41175]

Fostering Reproductive Resilience to Climate and Environmental Change

Play Episode Listen Later Jul 23, 2026 28:52


Climate and environmental change affect reproductive health and pregnancy in important ways. Dr. Marya Zlatnik explains how petrochemicals, climate change, and everyday chemical exposures can shape reproductive resilience and pregnancy outcomes. Zlatnik helps clarify how people can protect reproductive well-being in a changing climate with informed, resilience-building choices. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 41547]

Sleep in Children with Neurodevelopmental Differences

Play Episode Listen Later Jul 21, 2026 41:08


As part of the 2026 Developmental Disabilities Conference, Dr. Althea Robinson Shelton, Associate Professor of Neurology and Pediatrics, Vanderbilt University Medical Center, discusses sleep in children with neurodevelopmental differences. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 41466]

Serving Immigrant Clients: Family Perspectives on the Challenges and Solutions

Play Episode Listen Later Jul 21, 2026 27:34


As part of the 2026 Developmental Disabilities Conference, moderator Judy Mark and panelists Elizabeth Barrios Gomez, Mulugeta Tadele, Kyungshil Choi discuss the challenges and solutions for serving immigrant clients. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 41467]

Menopause and Healthy Aging

Play Episode Listen Later Jul 16, 2026 76:55


Menopause and healthy aging affect women's health and well-being in important ways. Dr. Tami Rowen explains how the best available evidence shapes menopausal management, with a focus on the data and safety around hormone therapy. Dr. Riley Bove examines brain, heart, gynecological, bone, and emotional health during the postmenopausal years, helping clarify how women can support health in this next phase of life. This work helps explain why evidence-based care matters and points toward practical strategies for healthy aging. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 41548]

Evidence-Based Approaches for Spasticity and Dystonia Management in People with Cerebral Palsy

Play Episode Listen Later Jul 14, 2026 39:37


As part of the 2026 Developmental Disabilities Conference, Dr. Bhooma Aravamuthan, Medical and Research Director, Cerebral Palsy and Mobility Center, Washington University in St. Louis, discusses evidence-based approaches for treating spasticity and dystonia management. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 41464]

Addressing Environmental Health for Children and Adolescents with Disabilities

Play Episode Listen Later Jul 14, 2026 39:55


As part of the 2026 Developmental Disabilities Conference, Jane Tobias, Associate Professor, Jefferson College of Nursing, discusses environmental health for children with disabilities. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 41465]

Resources in California for People with Developmental Disabilities Living with Aging Parents

Play Episode Listen Later Jul 9, 2026 41:49


As part of the 2026 Developmental Disabilities Conference, moderator Megan Cvitanovic leads a discussion with panelists Zorahida Preciado, Colette Patt, and Mechelle Johnson about resources for people with developmental disabilities who are living with aging parents. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 41460]

Early Roles of SYNGAP1 in Neurodevelopment: Insights from a Top Autism Risk Gene

Play Episode Listen Later Jul 5, 2026 28:48


Human brain organoids help researchers study neurodevelopmental disorders that are difficult to examine directly in developing brain tissue. Giorgia Quadrato, USC, uses cortical organoids derived from human pluripotent stem cells to examine SYNGAP1, an autism risk gene associated in the transcript with intellectual disability, epilepsy, and global developmental delay. Quadrato describes how SYNGAP1 appears in progenitor cells as well as neurons, and how SYNGAP1 haploinsufficiency is linked to disrupted radial glia organization, altered cell division, and faster maturation of cortical projection neurons. She also discusses newer work focused on enteric neurons, gastrointestinal symptoms, and gut motility. By connecting brain development, autism genetics, and the enteric nervous system, this research points to models that may help test therapies and better understand symptoms that affect families. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 41174]

Keeping the Promise: Healthcare Access for People with DD in California

Play Episode Listen Later Jul 2, 2026 39:45


As part of the 2026 Developmental Disabilities Conference, California State Senator Scott Wiener discusses healthcare access. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 41455]

Dementia in Down Syndrome: Is It Inevitable?

Play Episode Listen Later Jul 2, 2026 39:31


As part of the 2026 Developmental Disabilities Conference, Dr. Peter Bulova, Professor of General Internal Medicine, The University of Pittsburgh, discusses dementia in people with Down Syndrome. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 41458]

Heart Regeneration in Humans: Are We There Yet?

Play Episode Listen Later Jun 26, 2026 58:31


Heart regeneration faces two connected challenges: replacing lost muscle and keeping transplanted cells safe and accepted by the body. Charles Murry, M.D., Ph.D., of USC explains why the adult heart heals major cardiomyocyte loss with scar tissue rather than new muscle, leading to progressive heart failure. Murry describes how stem cell derived cardiomyocytes can be manufactured at scale, transplanted into injured hearts, and tested for function in animal models. He also examines major barriers, including graft related arrhythmias, calcium handling stress, immune rejection, and the need for practical immunosuppression or immune edited cells. By connecting cell manufacturing, electrophysiology, immunology, and clinical trial planning, this research shows why heart regeneration is difficult and why careful translation matters for patients with severe heart injury. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40853]

Fertility Optimization

Play Episode Listen Later Jun 24, 2026 81:30


Fertility health affects conception and reproductive planning in important ways. Jennifer Ashby, DAOM, and Maren Shapiro, MD, explain how East Asian medicine principles and daily habits shape fertility optimization. Ashby examines Jing, Blood, Qi, Yin/Yang balance, and stress, while Shapiro examines sleep, nutrition, exercise, supplements, timing intercourse, and when to seek additional support, helping clarify how the body can be supported before pregnancy. This work helps explain conception readiness and points toward practical strategies for reproductive health. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 41546]

Advances in Dental Care and Access to Care for People with Developmental Disabilities

Play Episode Listen Later Jun 22, 2026 45:24


As part of the 2026 Developmental Disabilities Conference, Dr. Paul Glassman, Professor and Associate Dean for Research and Community Engagement, College of Dental Medicine, California Northstate University, discusses dental care for people with developmental disabilities. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 41462]

Occupational Therapy Practice Guidelines for Autistic People Across the Lifespan

Play Episode Listen Later Jun 22, 2026 47:47


As part of the 2026 Developmental Disabilities Conference, Kavitha Murthi,Assistant Professor, Rutgers University, discusses occupational therapy for autistic people. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 41463]

Inflammatory Memory in Human Hematopoietic Stem Cells as a Driver of Clonal Selection in Aging and Cancer

Play Episode Listen Later Jun 19, 2026 58:55


Hematopoietic stem cells make blood across the lifespan, but they do not all behave the same way. Stephanie Xie, Ph.D., Scientist at Princess Margaret Cancer Centre, University of Toronto, examines how these rare cells self-renew, differentiate, and respond to inflammatory stress, asking whether differences in the stem cell pool help explain why aging affects people so differently. Xie identifies two hematopoietic stem cell subsets, including one that retains inflammatory memory after stress recovery, and connects this state to aging, clonal hematopoiesis, sickle cell disease, post-COVID recovery, and mortality risk markers in blood. Her research also raises questions about whether targeting the inflammatory environment, including through GLP-1 receptor agonists or metformin, could help mitigate clonal hematopoiesis. Understanding these patterns could clarify how inflammation shapes blood production, cancer risk, and immune health over time. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 41406]

Health in Adolescent Girls

Play Episode Listen Later Jun 17, 2026 76:31


Adolescent health affects the well-being of teen girls in important ways. Dr. Jenifer Matthews and Dr. David Becker explain how hormonal change and emerging technology shape physical and mental health. Matthews examines acne, PMS, and menstrual cycle irregularities, and offers integrative approaches to supporting teen hormonal balance, including key nutritional strategies and simple, safe herbal medicine options. Becker considers social media, AI companions, and integrative mental health care, helping clarify how teens can be supported through rapid change. This work helps explain common adolescent challenges and points toward practical, whole-person strategies. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 41545]

Health Policy Landscape for People with Developmental Disabilities

Play Episode Listen Later Jun 15, 2026 40:05


As part of the 2026 Developmental Disabilities Conference, Claudia Center, Legal Director, Disability Rights Education and Defense Fund talks about the health policy landscape. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 41453]

Aging (and Aging Caregivers) and Developmental Disabilities

Play Episode Listen Later Jun 15, 2026 41:04


As part of the 2026 Developmental Disabilities Conference, Tamar Heller, Director, Institute on Disability and Human Development, University of Illinois Chicago, discusses aging and aging caregivers. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 41459]

Gene Therapies and Rare Disease - Medicine Informing Novel Discoveries (MIND)

Play Episode Listen Later Jun 12, 2026 50:36


Rare disease research is creating new paths for diagnosis, treatment, and broader medical discovery. Gene therapy can repair or replace faulty genes, and work on cystinosis has led to a stem cell platform now being applied to Danon disease, Sanfilippo syndrome C, Friedreich's ataxia, and Alzheimer's research. Funding programs support gene therapy, clinical trials, and new platform approaches for rare diseases. CAR-T cell research is also advancing treatment possibilities for pediatric brain tumors, including early results in children with DIPG and diffuse midline glioma. A patient advocate shares her daughter's diagnostic odyssey and treatment for TUBB4A leukodystrophy. Together, these stories show why rare disease research matters beyond rarity. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 41402]

Prostate Cancer: Radiation Therapy for Local Recurrence

Play Episode Listen Later Jun 7, 2026 11:05


As part of the 2026 UCSF Patient Conference on Prostate Cancer, Dr. Steven Seyedin discusses radiation therapy. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 41558]

Stem-Cell Aging and Pathways to Precancer Evolution

Play Episode Listen Later Jun 5, 2026 22:04


Pre-cancer and cancer can begin when stressed blood-forming stem cells lose their normal controls. Catriona Jamieson, M.D., Ph.D., UC San Diego, explains how inflammation-linked editing enzymes, repetitive elements in the genome, and stem cell stress shape the progression from myeloproliferative neoplasms to acute myeloid leukemia. Jamison examines how spaceflight accelerates stem cell aging, how some astronauts mobilize a resilient regenerative stem cell population, and how tumor organoids in space help reveal drug responses by activating the enzyme ADAR1. This work helps explain how cancer starts, why it can return, and how space-based research may speed the development of therapies that stop malignant stem cells before disease advances. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 41473]

Prostate Cancer: PSMA PET and Functional Imaging

Play Episode Listen Later Jun 4, 2026 16:18


As part of the 2026 UCSF Patient Conference on Prostate Cancer, Dr. Spencer Behr discusses PSMA PET and functional imaging. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 41557]

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