UC San Diego (Audio)

Danielle K. Glorioso, LCSW, explores the complex nature of grief, emphasizing that it is a lifelong, evolving response to loss rather than something to “get over.” She explains the differences between acute grief, integrated grief, and prolonged grief disorder, highlighting how factors like attachment, personal history, and circumstances of death can influence the grieving process. Glorioso outlines how prolonged grief can impair daily functioning and discusses effective treatments, including a structured therapy program that facilitates adaptation. She also examines resilience as a skill that can be strengthened through emotion regulation, cognitive flexibility, social support, and meaning-making. Drawing on both professional expertise and personal loss, Glorioso offers practical strategies for coping, supporting others, and finding hope while honoring the memory of loved ones. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40332]

How do you find hope in a deeply fractured and polarized world? In this timely and powerful conversation, Pulitzer Prize–winning journalist Nicholas Kristof pulls from decades of reporting from global conflict zones and overlooked American communities to bring a deeply human perspective to today's most urgent moral and civic challenges. In an era marked by division and misinformation, this program explores how truth, empathy and ethical courage can shape a more just and compassionate world. This program is presented by the Burke Lectureship on Religion and Society, and moderated by The World's Marco Werman and UC San Diego Theater professor Allan Havis. Series: "Burke Lectureship on Religion and Society" [Public Affairs] [Show ID: 40914]

Stanley Chodorow, Emeritus Professor of History at UC San Diego, traces the evolution of food preservation, preparation, and production from ancient times to the modern era. He explores early methods such as drying, salting, and ice cellars, advances like iceboxes, refrigeration, and flash freezing, and innovations in cooking technology from open fires to gas and electric stoves. Chodorow examines the domestication of animals, the development of agriculture, and transformative tools like the wheeled plow and horse harness. He highlights the rise of industrialized food, refrigerated transport, and global trade in products such as sugar, chocolate, and processed foods. Concluding with the health impacts of dietary changes since the shift from hunter-gatherer to agricultural societies, he offers a sweeping view of how technology has shaped what—and how—we eat. Series: "Osher UC San Diego Distinguished Lecture Series" [Health and Medicine] [Science] [Show ID: 40966]

Sean Morrison, Ph.D., from the Children's Medical Center Research Institute at UT Southwestern, investigates how stem cells function, regenerate, and interact with their surrounding environment in the bone marrow. His research reveals how leptin receptor-positive cells—key components of the bone marrow niche—regulate hematopoietic stem cell maintenance and regeneration, influence platelet production, and respond to physiological stress like pregnancy. Morrison uncovers a reciprocal relationship between these niche cells and peripheral nerves, showing that disrupting nerve signals impairs bone marrow recovery after chemotherapy or radiation. His work also links retrotransposon activation during pregnancy to increased red blood cell production, with implications for maternal health and transplant medicine. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40449]

Deepak Srivastava, MD, explores how cellular reprogramming offers new hope for treating heart disease. He highlights innovative strategies to regenerate damaged heart tissue by stimulating adult cardiomyocytes to divide and converting fibroblasts into heart-like cells. His team develops a nonviral delivery system using lipid nanoparticles and investigates the role of specific gene regulators in restoring heart function in animal models. Srivastava also discusses a potential oral therapy for aortic valve disease, driven by insights into cellular fate changes caused by NOTCH1 mutations and telomere shortening. Additionally, he reveals how trisomy 21 may trigger congenital heart defects by altering the identity of specialized heart cells. Through pioneering research in genetics and regenerative medicine, Srivastava demonstrates how understanding developmental biology can lead to transformative clinical advances. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40447]

Kimberly Peters, a stage four uterine cancer patient at UC San Diego Health, urges government leaders not to cut science funding. She warns that reduced federal support risks delaying vital research and life-saving cures. [Health and Medicine] [Show ID: 41071]

Asteroids, often called “fossils of the solar system,” are remnants from its formation that offer clues about planetary origins and the potential beginnings of life. Dr. Neil Farber, Solar System Ambassador for NASA's Jet Propulsion Laboratory, explains that some, known as near-Earth objects, pose impact risks—though large, dangerous collisions are rare—and NASA's Near-Earth Object Surveyor mission aims to detect and track them to inform planetary defense strategies. Asteroids may also hold resources, such as metals or water, that could one day support space exploration, though current technology limits mining feasibility. Recent missions like OSIRIS-REx, Lucy, and Psyche are expanding our understanding of asteroid composition, history, and diversity, with findings including evidence of past water, amino acids, and nucleotide bases—key building blocks of life—raising intriguing questions about whether asteroids helped seed life on Earth. Series: "Osher UC San Diego Distinguished Lecture Series" [Science] [Show ID: 40964]

Hear about cutting-edge advances in regenerative medicine, from lab breakthroughs to patient impact. Catriona Jamieson, MD, PhD, introduces efforts at the Sanford Stem Cell Institute to develop therapies that enhance the body's ability to heal itself. Dan Kaufman, MD, PhD, shares progress in cancer immunotherapy using engineered natural killer cells derived from pluripotent stem cells. Karen Christman, PhD, explains how her team creates injectable hydrogels from pig heart tissue to support heart repair and regeneration after a heart attack. Tiffani Manolis highlights industry support for making cell and gene therapies more accessible. Patient advocate Justin Graves describes his life-changing experience receiving a stem cell-based therapy for epilepsy, underscoring the real-world promise of these innovations. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40705]

Ina Stelzer, Ph.D., explores how the maternal immune system adapts to support a healthy pregnancy and how disruptions can lead to complications like preterm birth. Her lab identifies early immune changes linked to spontaneous preterm birth and investigates the role of the maternal brain in regulating immune responses. Stelzer uses advanced technologies like mass cytometry and spatial proteomics to map immune and molecular changes in pregnancy, integrating these data with transcriptomics and mouse models. Her team studies how antidepressants affect immune signaling during pregnancy and examines the impact of social and behavioral factors. These insights may reveal biomarkers and therapeutic targets for improving maternal and fetal health. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40773]

Michael J. Wilkinson, M.D., F.A.C.C., F.N.L.A., explores the science and clinical evidence behind intermittent fasting and its role in promoting cardiometabolic health. He explains how aligning eating patterns with the body's natural circadian rhythms can improve weight, blood pressure, glucose regulation, and other risk factors, especially in individuals with metabolic syndrome or type 2 diabetes. Wilkinson highlights promising results from time-restricted eating studies conducted in collaboration with UC San Diego and the Salk Institute, where narrowing the daily eating window led to improved metabolic markers and potential benefits beyond weight loss. He also outlines practical tips for safely adopting this lifestyle approach and stresses the importance of ongoing research. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40319]

Amanda Lewis, Ph.D. investigates how glycan-degrading enzymes contribute to bacterial vaginosis (BV), a common condition linked to infertility, preterm birth, pelvic inflammatory disease, and increased cancer risk. Her research shows that BV-associated bacteria strip protective sugar coatings—glycans—from vaginal epithelial cells, disrupting normal function and increasing vulnerability to infection. Lewis and her team study specific enzymes, such as sialidases, that remove sialic acid from glycoproteins and mucins. Using clinical samples and imaging techniques, they identify how these changes in glycan composition correlate with disease severity. Their work reveals how glycan degradation contributes to persistent or recurrent BV and opens new pathways for understanding the microbiome's role in women's health. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40678]

AI and genetic medicine are converging to transform how we diagnose, treat, and prevent disease. Gene Yeo, Ph.D., unites RNA biology with artificial intelligence to speed the path from genome sequencing to personalized RNA therapeutics. Advances in sequencing have reduced costs dramatically, making interpretation and translation into treatments the real challenge. Using deep learning and large datasets of RNA-binding proteins, Yeo predicts disease vulnerabilities and identifies therapeutic targets, including in neurodegeneration and muscular diseases. Alexis Komor, Ph.D., focuses on DNA, explaining human genetic variation—particularly single-nucleotide variants—and how genome editing technologies like CRISPR can target them. She highlights strategies to correct harmful mutations and explores precise, programmable interventions. Together, their research drives discovery and enables more effective, personalized therapies. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40459]

Sarah Banks, Ph.D. explores why Alzheimer's disease affects women differently than men, emphasizing distinct patterns in tau pathology, cognitive testing bias, and treatment response. She explains how women tend to show a rapid buildup of tau during early cognitive decline, which may contribute to their higher prevalence of Alzheimer's. Banks also highlights how common diagnostic tools may overlook symptoms in women and how approved treatments may offer less benefit for them. Her research at UC San Diego investigates key sex-based differences in risk factors, including sleep apnea, diabetes, and exercise. One study reveals that over 70% of participating women had undiagnosed sleep apnea. Another focuses on Black women, using blood biomarkers to identify overlooked risks and improve care. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40768]

Louise Laurent, M.D., Ph.D., presents new insights into placental biology using cutting-edge molecular and imaging technologies. As part of the NIH-funded Human Biomolecular Atlas Program, her research focuses on mapping the structure and function of the placenta across gestation. By combining bulk RNA sequencing, single-cell analysis, spatial transcriptomics, and imaging mass cytometry, Laurent and collaborators identify key differences in cell types and gene expression associated with pregnancy stages and labor. Her team highlights how specific cells like syncytiotrophoblasts and extravillous trophoblasts evolve over time and interact with maternal tissue. This integrated approach offers an unprecedented view of placental development and lays the groundwork for understanding reproductive health and disease. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40670]

Marni Jacobs, Ph.D., M.P.H., presents the MOM Health Study, part of the NIH's Multi-Omics for Health and Disease (MOHD) Consortium, which investigates hypertensive disorders of pregnancy—such as preeclampsia—and their impact on postpartum health. The study aims to uncover the biological mechanisms linking these conditions to long-term maternal outcomes like stroke and heart disease. Unlike other disease sites, participants are enrolled before outcomes are known, allowing researchers to track 750 pregnancies through delivery and one year postpartum. Data collection includes surveys, biospecimens, placental tissue, and continuous blood pressure monitoring. By integrating clinical, environmental, and molecular data, the study supports early detection strategies and collaborative research to improve maternal health. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40671]

Lars Bode, Ph.D., presents the Human Milk Institute at UC San Diego, the world's first research center dedicated entirely to human milk. Established in 2022, the institute connects molecular research with clinical practice, community outreach, and public health. It unites multiple programs under one umbrella, including a milk bank for preterm infants, a biorepository, lactation education, and a rapid response team that helped inform WHO breastfeeding guidelines during COVID-19. The institute promotes collaboration across disciplines such as biology, engineering, social science, and public health. Through initiatives like the Human Milk Analytics Core, it advances maternal and infant health while highlighting the broader public health importance of breastfeeding. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40770]

Anthony Molina, Ph.D. highlights research and resources from the Stein Institute for Research on Aging that support healthy aging, with a focus on women's health. He describes the institute's work in training scientists, conducting clinical trials, and promoting community engagement. Key resources include a geroscience lab for biomarker discovery, new facilities for exposome and epigenetics research, and a clinical center for geriatric assessments. Molina also introduces the SAGE study—a 15-year prospective cohort project—and a “living lab” that enables real-world studies on technology and aging. The institute offers pilot funding for early-stage research and fosters intergenerational programs connecting older adults with medical students. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40767]

Science communication expert Lisa Warshaw and scientist Rob Signer, Ph.D., offer a practical guide to turning complex research into clear, memorable stories. They explain why strong openings, simple messages, vivid analogies, and visual storytelling are essential to making science resonate. The talk includes tips on avoiding jargon, using soundbites effectively, and preparing for high-stakes moments like media interviews and conference Q&As. Warshaw draws on her experience in global biotech and healthcare communications, while Signer shares real-world lessons from academic science and public engagement. Together, they highlight how clarity and creativity can elevate a researcher's voice, build trust with diverse audiences, and drive impact across fields. The session is filled with actionable insights for scientists aiming to connect their work with the world. Series: "Stem Cell Channel" [Humanities] [Science] [Show ID: 40460]

Jennifer Anger, M.D., M.P.H., Ph.D. investigates interstitial cystitis (IC), also known as painful bladder syndrome, with a focus on improving care through research on sex, gender, and health disparities. Using Veterans Affairs (VA) data, Anger challenges the outdated belief that IC predominantly affects women. She explores how comorbidities such as PTSD and depression, common among veterans, influence bladder pain, and examines how factors like exercisJennifer Anger, M.D., M.P.H., Ph.D. uses VA data to study interstitial cystitis.. She examines links between bladder pain, PTSD, depression, diet, and disparities to improve care across all gender identities.e, diet, and neighborhood deprivation impact symptoms. By including both cis and trans women as well as men, Anger seeks to advance more inclusive, data-driven understanding and treatment of IC across all populations. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40675]

Gladys (Sandy) Ramos, M.D. outlines the comprehensive maternal care services at UC San Diego, emphasizing clinical excellence, innovation, and community impact. She highlights programs in diabetes and pregnancy, high-risk obstetrics, postpartum and HIV care, and maternal mental health. Ramos describes cutting-edge capabilities in fetal and placental imaging, including expertise in placenta accreta and genetic counseling. A fetal surgery program is launching soon, expanding access to specialized care and research. The department's patient population closely reflects San Diego County's demographics, which informs both clinical care and research priorities. Ramos also details a collaborative structure with multidisciplinary conferences and welcomes partnerships in research related to maternal, placental, and fetal health. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40669]

UCLA's Avishek Adhikari, PhD, presents new research on the role of GABAergic neurons in the brain's periaqueductal gray (PAG) region. Previously studied for their involvement in fear and defensive behaviors, these neurons were found to promote food-seeking behavior when activated—even in fully fed mice. Using calcium imaging and optogenetics, Adhikari's team discovered that these neurons are active during food approach but suppressed during eating. The effect is stronger for high-value foods like chocolate or crickets and depends on the mouse's prior experience with that food. A key finding is that these neurons influence behavior through a specific projection to the zona incerta, a subthalamic region. Rather than signaling hunger, this pathway appears to drive food seeking based on reward value, highlighting a new motivational circuit in the brain. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40444]

Sheng Zhong, Ph.D. pioneers technologies that advance women's reproductive health. Zhong develops a minimally invasive method to analyze extracellular RNA secreted by embryos during IVF. By sequencing tiny samples of spent culture media, they generate comprehensive RNA profiles and use machine learning to identify biomarkers that predict embryo quality with accuracy comparable to traditional imaging. This breakthrough offers a gentler, data-driven alternative for assessing embryo viability, with the potential to improve live birth rates and support families navigating infertility. Zhong's research highlights the power of molecular innovation to transform fertility care and address critical challenges in women's health. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40676]

Antoni J. Duleba, M.D. outlines the broad scope of reproductive endocrinology and infertility, emphasizing care across a woman's lifespan—from adolescence through menopause. He explains common endocrine conditions like polycystic ovary syndrome (PCOS), endometriosis, and menstrual disorders, all of which can affect fertility and overall health. Duleba highlights advances in fertility preservation, especially for patients undergoing cancer treatment, and notes the rising need for such services as more women delay childbearing. He also addresses efforts to improve hormonal therapies, IVF outcomes, and treatments that target inflammation and the microbiome. In addition to medical innovation, he points to social and financial barriers that continue to limit access to reproductive care. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40672]

Join Fadel Zeidan, Ph.D. for a guided meditation. Follow along as he teaches simple breathing techniques and short practices designed to build focus and calm the nervous system. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40783]

Linda Brubaker, M.D. emphasizes the urgent need to advance women's health research beyond its traditional focus on reproduction, pregnancy, menopause, and breast cancer. She highlights the biological, social, and lifestyle factors that affect women across the lifespan and calls for greater inclusion of women in clinical research. Brubaker announces her leadership of a new JAMA initiative to centralize women's health content and promote rigorous scientific studies. She stresses that conditions like menopause and aging impact all areas of medicine and should be understood by all clinicians. Brubaker encourages collaboration, innovation, and resilience in pursuing high-quality science to support personalized care, healthy aging, and improved outcomes for all women. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40677]

Andrea Z. LaCroix, Ph.D. presents major public health trends affecting women across the lifespan, from rising maternal mortality and chronic disease risks linked to pregnancy complications to the ongoing need for improved menopause care. She highlights innovative research, including digital tools for menopause education, studies on cancer survivorship, and efforts to predict healthy aging using epigenetic clocks and physical activity data. LaCroix shows how decades of research continue to shape strategies for aging with preserved cognitive and physical function, aiming to help more women thrive into their 90s and beyond. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40766]

Emily Lukacz, M.D., M.A.S. presents research from two national networks focused on female pelvic floor disorders. One project studies bladder health in over 3,000 women to identify factors that support wellness rather than disease. Another conducts large-scale clinical trials, including a randomized study comparing two minimally invasive treatments for stress urinary incontinence. Additional trials include the TULIP study, which evaluates postpartum urinary symptom treatments using an app-based device, physical therapy, or educational materials, and a new study testing prescribed physical activity after pelvic surgery. These studies emphasize patient-centered outcomes and generate data available for further research and analysis. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40769]

Gretchen Bandoli, Ph.D., highlights four major research initiatives within her division focused on maternal and child health. The Center for Better Beginnings studies medication and vaccine safety during pregnancy and lactation through ongoing cohort studies. The Mommy's Milk Human Milk Research Biorepository collects breast milk samples to investigate postnatal exposures. The SOMI study links medical records and geolocated data for over 7 million California births to examine maternal-child health outcomes. Bandoli also leads a site for the Healthy Brain and Child Development Study, a national project following 7,500 mother-child pairs over the first ten years of life with neurodevelopmental assessments and biological sampling. All projects welcome collaboration and emphasize long-term outcomes. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40772]

In this Osher lecture, Kuiyi Shen, Professor or Art History, Theory and Criticism at UC San Diego, gives a historical overview of Japanese art during the zenith of court culture. Series: "Osher UC San Diego Distinguished Lecture Series" [Arts and Music] [Show ID: 40870]

The human body has traits that evolved at different times, from 1.5 billion to 2 million years ago, each bringing health benefits and risks. Multicellularity enabled organs and cancer. The immune system defends us but can cause inflammation. Breastfeeding supports infant health but relates to breast cancer risk. Menstruation and invasive placentas improved reproduction but led to pain and cancer risks. Human-specific traits like bipedalism and aging brought new issues like back pain and childbirth problems. Hair loss and sweat glands helped us stay cool but increased skin cancer risk. Our hunter-gatherer past shaped our microbiome and health, but also made us prone to modern diseases from lifestyle changes. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40702]

Humans have long been exposed to three main types of smoke: from early domestic fires, modern wildfires, and more recently, tobacco and fossil fuel pollution. All release tiny particles from partly burned plants, containing harmful chemicals like nitrogen oxides and carcinogens. These particles raise risks for lung cancer, dementia, and even childhood obesity. Studies show that air pollution can disrupt brain chemistry, increase Alzheimer's-related proteins, and activate stress-related genes (NFkB, Nrf2). A new drug (GSM-15606) shows promise in reducing brain damage from pollution in mice. People with the ApoE4 gene may be more vulnerable, while the ApoE3 gene, possibly evolved 200,000 years ago, may offer some protection. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40700]

What paradoxes arise when victims of related persecution tell their stories next to, and after, each other? This question is at the heart of Ari Joskowicz's highly acclaimed book “Rain of Ash,” which examines the unlikely entanglement of the histories of Jews and Romani people—the only two racialized groups the Nazis targeted for wholesale extermination. Joskowicz, professor of Jewish Studies at Vanderbilt University, explores the encounters between Jews and Romani people on the killing fields of Europe and seeks to understand how survivors and historians have discussed Romani and Jewish suffering during World War II in relational terms. Series: "Library Channel" [Humanities] [Show ID: 40533]

The human gut microbiome is tightly linked our health. Our analyses of diverse human populations from around the globe, ranging from hunter-gatherer to industrialized, show that the gut microbiome is profoundly influenced by lifestyle. With a large collaborative team, we conducted deep metagenomic sequencing of the gut microbiomes of Tsimane horticulturalists from Bolivia and compared them to those of Hadza hunter-gatherers from Tanzania. We are also investigating whether diet and microbial therapies can address deficiencies in the industrialized gut community. Molecular mechanisms of host-microbial interaction are pursued using an array of technologies and experimental approaches including gnotobiotic and conventional mouse models, quantitative imaging, and a metabolomics pipeline focused on investigating microbiota-dependent metabolites. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40698]

The human gut microbiome is tightly linked our health. Our analyses of diverse human populations from around the globe, ranging from hunter-gatherer to industrialized, show that the gut microbiome is profoundly influenced by lifestyle. With a large collaborative team, we conducted deep metagenomic sequencing of the gut microbiomes of Tsimane horticulturalists from Bolivia and compared them to those of Hadza hunter-gatherers from Tanzania. We are also investigating whether diet and microbial therapies can address deficiencies in the industrialized gut community. Molecular mechanisms of host-microbial interaction are pursued using an array of technologies and experimental approaches including gnotobiotic and conventional mouse models, quantitative imaging, and a metabolomics pipeline focused on investigating microbiota-dependent metabolites. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40698]

Frank Silva talks with writer and educator Eduardo Corvera about the power of reading, writing, and the humanities. They explore how stories help us understand ourselves and the world around us. Corvera shares insights on teaching, the writing process, and why being honest and curious is essential for young writers. It's a thoughtful and inspiring conversation about creativity, literature, and finding your own voice. Series: "Education Channel" [Humanities] [Education] [Show ID: 40620]

The essence of Being Human is the practice of Biocultural Reproduction (BCR). BCR is defined as the set of marriage and kinship based rules for extra-maternal cooperation in the production, feeding, and care of offspring. Human evolution theory needs to explain how people successfully combined a vastly extended period of offspring dependency and delayed reproduction with helpless newborns — with large heads and much body fat (even with problems giving birth) -- a short duration of breast-feeding, an adolescent growth spurt, and vigorous post-menopause valuable grandmothers. Are these characteristics a package or a mosaic? Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40697]

In this thoughtful presentation, Professor Emerita Laura Rendón, Ph.D., of the University of Texas - San Antonio, talks about her advocacy work in student preparation, access, and success. Her research has been published in education research journals and informed policies and practices within higher education that have transformed the lives of students. As the creator of the Validation Theory, she has helped redefine how we support and uplift students. Rendón is joined by Carolyn Sandoval, Ph.D., Senior Director of Instruction, UC San Diego, for a further discussion on how to advance student learning. [Education] [Show ID: 40679]

Musculoskeletal disorders are one of the most important challenges of modern medicine worldwide. They are often attributed to maladaptations of our body to our peculiar form of locomotion, upright bipedalism. This lecture will explore the evolutionary origin of major musculoskeletal disorders such as back problems and hip joint osteoarthritis. I will show that these problems represent a relatively recent phenomenon, occurring only during the last few decades, and thus are unrelated to our skeletal adaptations. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40696]

Phenotypic variation within the skeleton has biological, behavioral, and biomedical functional implications for individuals and species. Thus, it is critical to understand how genomic, environmental, and mediating regulatory factors combine and interact to drive skeletal trait development and evolution. One way to do this is by studying skeletal diseases that disrupt skeletal function — like osteoarthritis (OA) which is a chronic disorder characterized by the degradation of cartilage and underlying bone in joints and can lead to severe pain and mobility limitations. This talk will discuss what is known about OA in humans and other primates, as well as recent advances that are further informing these topics. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40695]

The rate of cancer and cancer malignancy differ greatly among mammalian species. The placental – maternal interface is also highly variable between placental mammals. This lecture will discuss recent advances that suggest that there is a causal connection between the evolution of placental biology and the biology and rate of cancer malignancy. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40694]

Experts discuss recent advances in how maternal health and immune function during pregnancy affect infant development and long-term outcomes. Research focuses on immune adaptations, complications like preterm birth, and neuroimmune pathways, using techniques such as mass cytometry, spatial proteomics, and chemogenetics to identify biomarkers and mechanisms that guide prevention and treatment strategies. Sandy Ramos, M.D. Clinical Landscape and OGRS Opportunities Louise Laurent, M.D.,Ph.D. Single-Cell and Spatial Multi-Omic Insights into the Human Placenta (HUBMAP) Marni Jacobs, Ph.D. The MOM-Health Study and the MOHD Consortium Lars Bode, Ph.D. Human Milk Institute (HMI) Gretchen Bandoli, Ph.D. MotherToBaby Ina Stelzer, Ph.D. Reproductive Immunology Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40666]

Explore key aspects of aging and menopause, focusing on women's health and how biological changes impact overall well-being. Experts discuss current research on healthy aging, including the role of physical activity, brain health, and hormone changes during menopause. They highlight how sex differences affect diseases like Alzheimer's and emphasize the importance of personalized approaches to treatment and prevention. The presentation also underscores ongoing studies and resources aimed at improving the quality of life for aging women through better understanding and support Linda Brubaker, M.D.,M.S. Clinical Landscape and OGRS Opportunities Amanda Lewis, Ph.D. Glycobiology (GLOW) Andrea LaCroix, Ph.D. Healthy Aging After Menopause Anthony Molina, Ph.D. Stein Institute for Research on Aging Sarah Banks, Ph.D. Alzheimer in Women Emily Lukacz, M.D.,M.A.S. Prevention of Lower Urinary Tract Symptoms (PLUS) Research Consortium and Pelvic Floor Disorders Network (PFDN) Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40668]