Podcasts about uc san diego

Send us Fan Mail In this episode of Your Child Is Normal, Dr. Jessica Hochman talks with pediatric sleep specialist Dr. Bhattacharjee, who leads the sleep program at Rady Children's Hospital, about why sleep is so important for children's physical health, mood, learning, attention, and athletic performance.They discuss why teenagers naturally want to stay up later, how early school schedules work against adolescent biology, and what parents can realistically do to help. Dr. Bhattacharjee shares practical advice about screens, phones in the bedroom, caffeine, weekend sleep schedules, bedtime routines, and figuring out how much sleep your individual child actually needs.They also discuss the connection between sleep deprivation and ADHD-like symptoms, whether sleep helps children grow, melatonin and other sleep aids, when excessive sleepiness deserves medical attention, and why consistency may be one of the most underrated sleep strategies.Learn more about Dr. Bhattacharjee: Dr. Bhattacharjee practices at UC San Diego and Rady Children's Hospital in San Diego and is an active member of the American Academy of Sleep Medicine. Make sure and Follow Your Child Is Normal  podcast for practical, evidence-based conversations designed to help parents learn more and worry less.Your Child is Normal is the trusted podcast for parents, pediatricians, and child health experts who want smart, nuanced conversations about raising healthy, resilient kids. Hosted by Dr. Jessica Hochman — a board-certified practicing pediatrician — the show combines evidence-based medicine, expert interviews, and real-world parenting advice to help listeners navigate everything from sleep struggles to mental health, nutrition, screen time, and more. Follow Dr Jessica Hochman:Instagram: @AskDrJessica and Tiktok @askdrjessicaYouTube: Ask Dr JessicaShop my favorite products for kids on Amazon hereIf you are interested in placing an ad on Your Child Is Normal click here or fill out our interest form.To test your child's microbiome and get recommendations, check out: Tiny Health using code: DRJESSICA The information presented in Ask Dr Jessica is for general educational purposes only.  She does not diagnose medical conditions or formulate treatment plans for specific individuals.  If you have a concern about your child's health, be sure to call your child's health care provider.

Hidden dynamics of anti-colonialism come to light when exploring the Syrian revolt of 1925 through a transnational lens. Associate Professor & Author Reem Bailony shares insights from her book, examining how the diaspora politics of the Syrian migrant community in the US connected to homeland politics and redefined identity during the French mandate. By centering on the often-overlooked diasporic story and the role of the Arabic press, the conversation unpacks the intense debate around the rebellion's virtues, goals, and shifting meanings. Ultimately, this episode reveals how exiled and migrant figures significantly shaped the international discourse surrounding the modern Middle East.   00:00 Introduction 00:52 Formative Academic Encounters with a Milestone Year 04:36 From Imperial Collapse to the Partitioning of a Region 07:30 Fragmented Visions & the Contested Landscape of Identity 10:08 Archival Discoveries & Cross-Generational Reflections 12:34 The Global Power of a Dispersed Press 16:13 The Mechanics of Petitioning an International Order 20:12 Ideological Divides in the Early Arabic Press 22:26 Mapping the Global Hubs of the Transnational Story 24:28 Borderland Crises & the Politics of Transnational Aid 28:32 The Realities of Local Support 33:35 De Facto Diplomacy & the Pen of an Exile 36:34 Petitions, Surveillance, & the Struggle to Define a Diaspora 46:44 Recommended Readings for Closer Investigation   Reem Bailony is an Associate Professor of History at Agnes Scott College. She is a historian of the modern Middle East with a focus on Middle East migrations and transnationalism. Her book, Syria's Transnational Rebellion: Diaspora Politics and the Revolt of 1925-1927 (Edinburgh University Press, 2025) explores the diasporic and transnational dimensions of the Syrian Revolt of 1925-1927, a watershed moment in anti-colonialism during the French Mandate era. Professor Bailony is also interested in the history of Syrian-Lebanese transnational family dynamics after World War I, and how migrant families parented their children in the diaspora. She holds a BA from UC San Diego and MA and PhD from UCLA.   Connect with Reem Bailony

The same mathematics that explains why a fridge magnet sticks to your refrigerator also explains why neural networks work when they have no right to. His group did the calculation. Nobody else had. Subscribe if you want science with evidence, not speculation. Goldenfeld is a Professor of Physics at UC San Diego, a Fellow of the Royal Society, and a Member of the National Academy of Sciences who spent 36 years at the University of Illinois applying condensed matter physics to problems everyone else had given up on: why the genetic code is optimal, why early life evolved impossibly fast, and why AI works despite being overparameterized beyond anything classical statistics can explain. The thread connecting all three is one idea: that what emerges from many things together is qualitatively different from the sum of its parts. That idea explains magnetism, AI, the origin of the genetic code, and why life may be inevitable wherever the laws of physics apply. He also argues that what is happening to science right now is not a disagreement about facts but a fracture in how people decide what is true, and that is a more dangerous problem. What you'll hear: -Why the same phase transition that explains magnetism also explains why AI works at all -Why Francis Crick concluded life must have come from outer space and what Goldenfeld found instead -What horizontal gene transfer has to do with how libraries work -Why Goldenfeld thinks Enceladus is a better bet for life than Europa -The purpose of life, stated as a thermodynamics problem -Why “different is more” is more useful than “more is different” “The impact you make is the ratio of what you do divided by what everybody else does. Minimize the denominator.” — Nigel Goldenfeld CHAPTERS 00:00 AI shouldn't work. It does. 00:56 What is a phase transition? 03:10 What the renormalization group does 08:54 Ising gave up. Wrong dimension. 13:32 Nigel almost met Ising. 40 minutes away. 26:38 AI is the best example of more is different 33:52 Bardeen won two Nobels. The transistor looked like chewing gum. 37:24 The three mysteries Crick couldn't solve 46:20 The genetic code can't evolve. And yet it did. 49:00 How early life evolved like a library 57:06 The purpose of life as a physics problem 01:00:04 Life is physics, not chemistry 01:05:56 Anti-science age. Not because of opinions. 01:13:00 20 seconds with your 20-year-old self 01:17:14 Different is more Get the transcript, fascinating bonus content, and my Monday M.A.G.I.C. Message: https://briankeating.com/yt Have a .edu email and live in the USA? You automatically win a meteorite: https://BrianKeating.com/edu Subscribe: https://www.youtube.com/DrBrianKeating?sub_confirmation=1 Support Into the Impossible on Patreon, get my weekly M.A.G.I.C. Message, unfiltered bonus content, and live monthly Office Hours with me: https://www.patreon.com/drbriankeating Join this channel for perks, monthly Office Hours, and your name in the Member Roster at the end of every episode: https://www.youtube.com/channel/UCmXH_moPhfkqCk6S3b9RWuw/join Featured Guest: Nigel Goldenfeld website: https://guava.physics.ucsd.edu/~nigel/ Lectures on Phase Transitions and the Renormalization Group: https://www.amazon.com/dp/0201554097?lv=shuf&channelId=500&plpRedirect=mhFallbackNigel Goldenfeld on Twitter/X: https://x.com/NigelGoldenfeld My books: Losing the Nobel Prize (memoir): http://amzn.to/2sa5UpA Think Like a Nobel Prize Winner: https://a.co/d/03ezQFu Focus Like a Nobel Prize Winner: https://a.co/d/hi50U9U Galileo's Dialogue (first-ever audiobook): https://a.co/d/iZPi9Un Twitter/X: https://x.com/BrianKeating Substack: https://briankeating.substack.com Blog: https://briankeating.com/blog Audio-only: https://briankeating.com/podcast #intotheimpossible #briankeating #NigelGoldenfeld #physics #AI #originoflife #condensedmatterphysics #podcast Learn more about your ad choices. Visit megaphone.fm/adchoices

Hot flashes, blood sugar swings, brain fog... is it menopause, diabetes, or both?In this episode of the TCOYD Podcast, Dr. Steve Edelman is joined by renowned menopause expert Dr. Cindy Stuenkel, endocrinologist and Professor Emerita at UC San Diego, for an insightful conversation about how menopause affects women living with diabetes. Together, they explain why menopause is much more than a normal stage of aging. It's a major metabolic transition that can influence blood sugar management, insulin resistance, heart health, sleep, mood, and overall quality of life. The conversation explores what actually happens during perimenopause, menopause, and postmenopause, why hormonal fluctuations can make glucose management more challenging, and how continuous glucose monitoring can help distinguish hot flashes from hypoglycemia. Dr. Edelman and Dr. Stuenkel also discuss the latest evidence on hormone replacement therapy, newer non-hormonal treatment options, the importance of protecting heart health, and practical strategies to help women navigate this stage of life with greater confidence. Whether you're living with type 1 or type 2 diabetes, approaching menopause, currently experiencing it, or supporting someone who is, this episode provides practical guidance and evidence-based information to help you feel more prepared. Key TopicsWhat is perimenopause, menopause, and postmenopause?How hormonal changes affect blood sugar and insulin resistanceWhy menopause can increase glucose variability in women with diabetesThe difference between hot flashes and hypoglycemiaHow continuous glucose monitoring can help during menopauseMetabolic changes that occur during the menopause transitionWhy cardiovascular risk increases after menopauseThe connection between menopause, weight gain, and abdominal fatGLP-1 medications and menopauseThe latest recommendations on hormone replacement therapyNew non-hormonal treatments for hot flashesSleep, mood, brain fog, and quality of life during menopauseHeart health strategies for women living with diabetesHow partners can better support someone going through menopauseTrusted menopause resources and when to seek medical care Subscribe for practical diabetes management tips, expert conversations, and the latest advances in diabetes care to help people living with diabetes live healthier, more confident lives. ★ Support this podcast ★

You've probably been told that anxiety is a reaction to what's happening in your life. But my guest today says that's not the whole story. Most of your anxiety isn't a reaction to what's actually happening — it's a reaction to what you're imagining might happen. You get an email that says "can we talk tomorrow?" and your mind writes an entire disaster. Your brain then releases the same stress hormones whether the threat is real or imagined. My guest is Dr. Cassandra Vieten, a licensed clinical psychologist and director of research at the Arthur C. Clarke Center for Human Imagination at UC San Diego. Her new book is Imagine That. Some of the things we discuss are: Why you're imagining far more than you think — and how your brain reacts as if what you're imagining is actually happening The Mark Twain quote about worry that will stop you in your tracks Why "just think positive" backfires — and what to do with your imagination instead Your imagination profile — why some people see vivid pictures, others hear narrated stories, and both are valid ways of imagining How to visit your future self — and the surprising question to ask when you get there How to tell the difference between rumination and imagination The dragon-in-the-village metaphor Dr. Vieten uses for addiction — and why a good story can reach truths your logical mind can't The Therapist's Take: My top three strategies for using your imagination to grow mentally stronger Related Episodes ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠318 — How to Turn Anxiety Into a Competitive Advantage With a 2-Minute Play That Tricks Your Brain ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠144 — 7 Surprising Strategies That Fix Anxiety (Even Though We Fear These Things Will Make Anxiety Worse) Links & Resources ⁠Imagine That Connect with the Show Buy a copy of⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠13 Things Mentally Strong People Don't Do⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Connect with Amy on Instagram —⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@AmyMorinAuthor⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Sign Up for My Newsletter —⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://amymorinlcsw.com/newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Sponsors Lola Blankets - Head to⁠⁠⁠ LolaBlankets.com⁠⁠⁠ and use code STRONGER to get 40% OFF your order. AirDoctor — Head to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠AirDoctorPro.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠and use promo code STRONGER to get UP TO $300 off today! One Skin — Go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠oneskin.co/STRONGER⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ and use code stronger to get up to 30% off your first 3 subscription orders Quince — Go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Quince.com/stronger⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for free shipping on your order and 365 day returns! Boll & Branch — Get 20% off sitewide at ⁠⁠⁠⁠⁠⁠⁠⁠BollAndBranch.com/stronger⁠⁠⁠⁠⁠⁠⁠⁠ with code stronger. Square — Get up to $200 off Square hardware at ⁠⁠⁠⁠⁠square.com/go/STRONGER⁠⁠⁠⁠⁠. Dupe — Go to⁠⁠⁠⁠⁠ Dupe.com ⁠⁠⁠⁠⁠to finally feel confident about what to buy. Subscribe to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Mentally Stronger Premium⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for exclusive content like weekly bonus episodes, mental strength challenges, and office hours with me. Learn more about your ad choices. Visit megaphone.fm/adchoices

Why do nearly half of IR residents consider leaving the specialty, and what can be done to change that? On this episode of the BackTable Podcast, Dr. Neil Jain interviews Dr. David Mittelstein, an integrated IR resident at UC San Diego and co-chair of the SIR RFS Recruitment Committee, about the findings of a national SIR survey on interventional radiology resident attrition. They discuss what drives uncertainty, from lifestyle and call burden to job market fears, and highlight the program features that encourage retention, such as structured training, high case volume, and a culture of camaraderie. --- Get the BackTable apphttps://www.backtable.com/app --- This podcast is supported by RADPAD® Radiation Protectionhttps://www.radpad.com/ --- Timestamps 00:00 - Introduction04:31 - From Biomedical Engineering to IR07:41 - Recruitment Committee Mission12:37 - Match Trends Warning Sign15:12 - Survey Design Demographics20:21 - What Factors Matter25:04 - Why Residents Consider Switching30:23 - Recommendation 1 IR Curriculum32:32 - Recommendation 2 More IR Rotation34:10 - Recommendation 3 Build Camaraderie38:30 - Advice for Residents Who Are Doubting41:00 - What's Next for RFS Recruitment43:20 - Wrap Up --- More about this episode The conversation explores free-response themes from the survey, where 78 percent of residents cited lifestyle concerns, 31 percent pointed to job market uncertainty, and 22 percent mentioned call experience as reasons for questioning IR. Retention was linked to structured training (38 percent), high case volume and procedural experience (35 percent), and program camaraderie (18 percent). Dr. Mittelstein and Dr. Jain review three concrete recommendations to improve retention, examine early changes at programs like Georgetown, and offer practical advice to residents who may be quietly doubting their path in IR. --- Resources Episode # 554 Optimizing the IR/DR Curriculum & Experience https://www.backtable.com/shows/vi/podcasts/554/optimizing-the-ir-dr-curriculum-experience --- BackTable Vascular & Interventional (VI) is the go-to podcast for interventional radiologists, vascular surgeons, and interventional cardiologists. Download the free BackTable app to get early access to new episodes, cases, and courses curated by physicians in your specialty. ► https://www.backtable.com/app

Cannabis is often discussed as either a miracle remedy or a dangerous drug, but the reality is far more nuanced. In this episode, Dr. Jen speaks with naturopathic doctor and cannabinoid researcher Dr. Michelle Sexton about the endocannabinoid system, medical cannabis, chronic pain, sleep, inflammation, menopause, and opioid reduction. They explore why dose, age, product quality, delivery method, and THC potency all matter, how cannabis differs from CBD, and why modern high-potency products are not the same as the cannabis used decades ago. Dr. Sexton also shares practical guidance on starting low, avoiding unnecessary exposure during brain development and pregnancy, and using cannabis as a carefully considered medical tool rather than a one-size-fits-all solution.Dr. Michelle Sexton, ND, is a licensed naturopathic doctor, researcher, author, and internationally recognized expert on cannabinoid pharmacology and the endocannabinoid system. She completed her naturopathic medical training at Bastyr University and an NIH-funded postdoctoral fellowship at the University of Washington, where she studied cannabis, immune function, neuroinflammation, and neurodegeneration. Dr. Sexton has also served as an Assistant Adjunct Professor in the Department of Anesthesiology at UC San Diego and has worked with patients through the university's Center for Integrative Medicine. Her work focuses on translating cannabinoid science into responsible, practical guidance for pain, sleep, inflammation, women's health, and opioid reduction. Website: https://www.msextonnd.com LinkedIn: https://www.linkedin.com/in/michelle-sexton-a40408b  Facebook: https://www.facebook.com/msextonnd  PODCAST: Thank you for listening please subscribe and share! Shop supplements: https://healthybydrjen.shop/CHECK OUT a list of my Favorite products here: https://www.healthybydrjen.com/drjenfavoritesFOLLOW ME:Instagram: https://www.instagram.com/integrativedrmom/Facebook:  https://www.facebook.com/integrativedrmomYouTube: https://www.youtube.com/@integrativedrmomFTC: Some links included in this description might be affiliate links. If you purchase a product through one of them, I will receive a commission (at no additional cost to you).  I truly appreciate your support of my channel. Thank you for watching! Video is not sponsored.DISCLAIMER: This podcast does not contain any medical or health related diagnosis or treatment advice. Content provided on this podcast is for informational purposes only.  For any medical or health related advice, please consult with a physician or other healthcare professionals. Further, information about specific products or treatments within this podcast are not to diagnose, treat, cure or prevent disease.

In this episode, author Dr. Cassandra Vieten explores the science and practice of imagination, its role in manifestation, creativity, and personal growth. Kimberly and Cassandra discuss how imagination can be cultivated, its connection to happiness, and its potential to solve complex problems.Chapters00:00 Introduction to the Power of Imagination00:01 Imagination as a Tool for ManifestationSponsor:BIRCH BEDS OFFER: Birch Organic Mattresses. Listeners now can go to birchliving.com/feelgood and receive 27% percent off any Mattress USE LINK: birchliving.com/feelgood and receive 27% percent off any Mattress Guest Resources:Book: Imagine That: Transform How You Think, Feel, and Live with the Science of ImaginationWebsite: cassandravieten.comBio: Cassandra Vieten, PhD, is a licensed clinical psychologist, clinical professor in the department of family medicine, and director of research at the Arthur C. Clarke Center for Human Imagination at the University of California, San Diego. She also directs the Center for Mindfulness at UC San Diego and serves as clinical psychology director at the Center for Psychedelic Research. She is senior advisor at the John W. Brick Mental Health Foundation and a senior fellow at the Institute of Noetic Sciences. Her research has focused on imagination, spirituality and health, transformative experiences and practices, the development of mindfulness-based interventions for emotional well-being, and development of media technologies to inspire awe. She has authored three books, is a three-time TEDx speaker, has published numerous articles in scientific journals, and is an internationally recognized keynote speaker and workshop leader.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Kathryn Schulmeister joins the podcast to talk about Imagining Hands, her debut solo album on Protomaterial Records. A bassist, improviser, composer, and University of Wisconsin faculty member, Kathryn brings together contemporary music, storytelling, extended technique, and deeply personal experience in a project shaped by her time at UC San Diego, her work with Mark Dresser, and the narrative world of Clarissa Pinkola Estés' Women Who Run With the Wolves. We dig into the album's connection to The Handless Maiden, the thread-and-tabletop bass techniques behind "Underground Forest," the prepared-bass sounds of "Harrowing," the role of injury and recovery in "Silver Hands," and how contemporary music can expand what bassists imagine is possible on the instrument. Kathryn also reflects on growing up in Hawaii, discovering contemporary improvisation at New England Conservatory, studying at McGill and UCSD, working with ELISION Ensemble in Australia, and why classical, experimental, and improvisational practices can strengthen each other. Enjoy, and follow Kathryn on her website and Instagram, and listen to Imagining Hands on Bandcamp, Spotify, and Apple Music! Thank you to our sponsor! Carnegie Mellon University Double Bass Studio – CMU is dedicated to helping each student achieve their goals as a musician. Every week each student receives private lessons and participates in a solo class with Micah Howard. Peter Guild, another member of the PSO, teaches Orchestral Literature and Repertoire weekly. They encourage students to reach out to the great bassists in their area for lessons and direction. Many of the bassists from all of the city's ensembles are more than willing to lend a hand. Every year members of the Symphony, the Opera and the Ballet give classes and offer our students individual attention. Click here to visit Micah's website and to sign up for a free online trial lesson.   Connect with DBHQ Join Our Newsletter Double Bass Resources Double Bass Sheet Music Double Bass Merch Gear used to record this podcast Zoom H6 studio 8-Track 32-Bit Float Handy Recorder Rode Podmic Sony Alpha 7 IV Full-frame Mirrorless Interchangeable Lens Camera Sony FE 16-35mm F2.8 GM Lens Sony FE 24-70mm F2.8 GM Lens   When you buy a product using a link on this page, we may receive a commission at no additional cost to you. Thank you for supporting DBHQ.   Theme music by Eric Hochberg

If you're living with MS and wondering whether pregnancy is still on the table for you… this episode is for you. Maybe you just saw two lines on a test and your first thought wasn't joy, it was "what do I do about my medication?" Maybe you're a year out from trying and you want to plan this right. Either way, you deserve real answers, not a shrug. In this episode, I'm joined by Dr. Christina Chambers, PhD, MPH, a perinatal epidemiologist and professor of pediatrics at UC San Diego. She has spent her career studying what medications and exposures actually do during pregnancy and breastfeeding, and she brought all of it to this conversation about multiple sclerosis (MS) and pregnancy. We covered the questions people with MS ask most, and a few they're often too nervous to ask out loud. Here's what we cover

Today, you are going to learn the science of manifestation, visualization, and imagination - and the steps you can take to start creating the life you want. In this powerful episode, Mel sits down with Dr. Cassandra Vieten, PhD, a clinical psychologist, professor at UC San Diego, and one of the world's leading researchers on imagination and consciousness. Dr. Vieten directs the Center for Human Imagination at UC San Diego, leads the Center for Mindfulness at UC San Diego's Centers for Integrative Health, and her research has been cited more than 5,000 times. Together, Mel and Dr. Vieten unpack the science behind changing your mindset in order to change your life. You'll discover how your mind shapes your reality and learn practical, research-backed techniques to shift your thinking and create new possibilities. In this episode, you'll learn: -The difference between manifestation and magical thinking -How your imagination shapes your decisions, identity, and future -How to stop reacting to life and start intentionally creating it -How to use visualization even if you do not naturally see pictures in your mind -Why imagining the worst case keeps your body stuck in stress -How to meet your future self and use that vision to make better decisions today -How to break out of a “reality tunnel” and see possibilities you have been missing Dr. Vieten's research is clear: Your imagination is not an escape from reality. It is one of the most powerful tools you have to change how you see your life, what you believe is possible, and what you do next. By the end of this episode, you will know how to get off autopilot, break free from the stories holding you back, and use imagination, visualization, and manifestation to start creating a more intentional and hopeful future. For more resources related to today's episode, click here for the podcast episode page.  If you liked this episode, listen to this one next: #1 Mindset Expert: Simple Mindset Shifts That Transform Your Body, Energy, & Life Mel wants to add:   Try the 23g protein shot I drink every single morning Join 2 million readers loving my weekly newsletter - full of tips, tools, and inspiration The Let Them Theory: read the book everyone's talking about Watch the episodes on YouTube Connect with me on Instagram Follow the show's Instagram for clips, behind the scenes, and more Find some daily positivity on my TikTok Want zero ads? Subscribe to SiriusXM Podcasts+ to listen to new episodes ad-free Disclaimer Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Topology offers a way to organize complex data by looking for shape, structure, and relationships. Yusu Wang, Ph.D., UC San Diego, and Gunnar E. Carlsson, Ph.D., Stanford University, discuss how ideas from algebraic topology move from pure mathematics into data science, machine learning, and AI. Carlsson explains why topological data analysis helps identify meaningful groups in large data sets, how examples and accessible tools can make abstract math useful, and why interpretability matters as AI systems grow more complex. The conversation connects collaboration across fields, customer-focused entrepreneurship, and the need to train mathematicians and AI researchers to help formulate real-world problems. Their exchange shows how mathematical thinking can make powerful technologies more understandable, usable, and accountable. Series: "Data Science Channel" [Science] [Show ID: 41487]

Topology offers a way to organize complex data by looking for shape, structure, and relationships. Yusu Wang, Ph.D., UC San Diego, and Gunnar E. Carlsson, Ph.D., Stanford University, discuss how ideas from algebraic topology move from pure mathematics into data science, machine learning, and AI. Carlsson explains why topological data analysis helps identify meaningful groups in large data sets, how examples and accessible tools can make abstract math useful, and why interpretability matters as AI systems grow more complex. The conversation connects collaboration across fields, customer-focused entrepreneurship, and the need to train mathematicians and AI researchers to help formulate real-world problems. Their exchange shows how mathematical thinking can make powerful technologies more understandable, usable, and accountable. Series: "Data Science Channel" [Science] [Show ID: 41487]

Topology offers a way to organize complex data by looking for shape, structure, and relationships. Yusu Wang, Ph.D., UC San Diego, and Gunnar E. Carlsson, Ph.D., Stanford University, discuss how ideas from algebraic topology move from pure mathematics into data science, machine learning, and AI. Carlsson explains why topological data analysis helps identify meaningful groups in large data sets, how examples and accessible tools can make abstract math useful, and why interpretability matters as AI systems grow more complex. The conversation connects collaboration across fields, customer-focused entrepreneurship, and the need to train mathematicians and AI researchers to help formulate real-world problems. Their exchange shows how mathematical thinking can make powerful technologies more understandable, usable, and accountable. Series: "Data Science Channel" [Science] [Show ID: 41487]

Topology offers a way to organize complex data by looking for shape, structure, and relationships. Yusu Wang, Ph.D., UC San Diego, and Gunnar E. Carlsson, Ph.D., Stanford University, discuss how ideas from algebraic topology move from pure mathematics into data science, machine learning, and AI. Carlsson explains why topological data analysis helps identify meaningful groups in large data sets, how examples and accessible tools can make abstract math useful, and why interpretability matters as AI systems grow more complex. The conversation connects collaboration across fields, customer-focused entrepreneurship, and the need to train mathematicians and AI researchers to help formulate real-world problems. Their exchange shows how mathematical thinking can make powerful technologies more understandable, usable, and accountable. Series: "Data Science Channel" [Science] [Show ID: 41487]

Audible Bleeding Editor and vascular surgery fellow Richa Kalsi (@KalsiMD) is joined by James Martinson,  practicing general surgeon with an interest in vascular surgery currently serving as the ship's surgeon for the USS Harry S Truman aircraft carrier and Langford Green (@langfordgreen_), research fellow at the Center for Vascular Research at the University of Maryland currently applying to medical school, JVS editor Dr. Audra Duncan (@ADuncanVasc), and JVS-VI editor Dr. Anahita Dua (@AnahitaDua) to discuss two great articles in the JVS family of journals. Articles: Part 1: Open bypass versus endovascular therapy in chronic limb-threatening ischemia patients with prior endovascular attempts (Hamouda & Malas) Part 2: Retrospective review of 3126 patients with chronic lower extremity wounds treated with intermittent topical oxygen therapy (Lohr & Dua) Show Guests  Dr. Mohammed Hamouda was a postdoctoral research fellow at UC San Diego, Division of Vascular & Endovascular Surgery, and an incoming integrated vascular surgery resident at the Houston Methodist Hospital (LinkedIn) Dr. Mahmoud Malas is the chief of vascular and endovascular surgery at UC San Diego, and the vice chair of surgery for clinical research at UC San Diego School of Medicine (@malas_mahmoud) Dr. JoAnn Lohr is a vascular surgeon with her own practice in Cincinnati, OH, and has also worked in the VA system of Columbia, SC (LinkedIn) Follow us @audiblebleeding Learn more about us at https://www.audiblebleeding.com/about-1/ and provide us with your feedback with our listener survey. *Gore is a financial sponsor of this podcast, which has been independently developed by the presenters and does not constitute medical advice from Gore. Always consult the Instructions for Use (IFU) prior to using any medical device.

Dave Ginsburg is joined by Marty Jencius and Jill McKinley to discuss a study showing Apple Vision Pro helping surgeons complete procedures faster, the latest iOS, iPadOS, macOS, and AirPods beta updates, and an important Mac screen-sharing security fix. They also cover MacBook Air shortages, the coming end of Rosetta 2, an iCloud Private Relay IP leak, CarPlay on pontoon boats, September iPhone rumors, higher Apple Trade In values, Ted Lasso's return, Madden NFL 27 on Apple Arcade, and more. The show notes are at InTouchwithiOS.com  Direct Link to Audio  Links to our Show Give us a review on Apple Podcasts! CLICK HERE we would really appreciate it! Click this link Buy me a Coffee to support the show we would really appreciate it. intouchwithios.com/coffee  Another way to support the show is to become a Patreon member patreon.com/intouchwithios Website: In Touch With iOS YouTube Channel In Touch with iOS Magazine on Flipboard Facebook Page BlueSky Mastodon X Instagram Threads Summary In this episode of In Touch With iOS, Dave Ginsburg, Marty Jencius, and Jill McKinley explore how Apple technology continues to expand into unexpected places. A peer-reviewed UC San Diego study found surgeons using Apple Vision Pro as their primary display during tear duct procedures completed operations about 19% faster than those using a traditional monitor, while maintaining successful outcomes. The panel also shares a fun Vision Pro encounter at Chicago O'Hare and considers how Apple's spatial computing platform is finding practical uses beyond entertainment. The discussion moves to Apple's latest software developments, including beta updates for AirPods, iOS, iPadOS, and macOS. New AirPods features include an updated interface, adaptive mode controls, custom EQ support, and translation capabilities, while iPadOS and iOS bring interface refinements, greater customization, and new Apple Intelligence photo tools. On the Mac, the panel highlights an important security update addressing a screen-sharing vulnerability, reports of significant MacBook Air supply constraints, and Apple's approaching sunset of Rosetta 2 support after macOS 27. They also examine reports that iCloud Private Relay can expose a user's real IP address under certain passkey-related circumstances. Other topics include CarPlay expanding to select pontoon boats, preparations and rumors surrounding Apple's September iPhone event, increased Apple Trade In values, the return of Ted Lasso, Madden NFL 27 joining Apple Arcade, new Apple Card travel benefits, the possibility of a free ad-supported Disney+ tier, and Leagues Cup 2026 coverage on Apple TV. Topics and Links In Touch With Vision Pro this week.  Apple Vision Pro Speeds Up Surgery by Almost 20% Cool VisionPro interaction with an old lady Beta this week.  iOS 27.0 Beta 4 continues 17 days since release Apple Releases New AirPods Beta Firmware With iOS 27 Features Set a Custom EQ for Your AirPods in iOS 27 iPadOS 27 adds two new iPad features I've been loving  iOS 27 adds four new ok ways to customize your iPhone's Lock Screen iOS 27's best new Messages feature is all about saving you time  all-new video from Cupertino to dive deeper into the biggest updates from WWDC26. In Touch With Mac this week Apple Releases macOS Tahoe 26.6.1 With Security Fixes Apple releases security updates to macOS Tahoe, Sequoia, and Sonoma Apple's latest macOS updates address a serious Screen Sharing vulnerability MacBook Air Experiencing 'Major' Shortage Despite $200 Price Increase Preparing for next year's Rosetta 2 demise Other Topics Apple's iCloud Private Relay is Leaking Users' Real IP Addresses CarPlay is Coming to Pontoon Boats Apple Starts Preparing for September iPhone Event Apple Raises Trade-In Values for iPhone, Mac, and More News Ted Lasso Season 4 Now Streaming on Apple TV Review: "Ted Lasso" returns, refreshed, to the pitch Madden NFL 27 Arcade Edition Now Available on Apple Arcade Apple Card Now Fast-Tracks Booking.com Perks With Just One Trip Disney+ Could Get a Free Ad-Supported Tier Leagues Cup 2026 Kicking Off on Apple TV This weeks "Things we found" Dave- QNAP TR-004 4 Bay USB Type-C Direct Attached Storage https://a.co/d/0hGa513m Dave Bonus Pick Tom Bihn Medium Cafe Bag https://www.tombihn.com/collections/all-tom-bihn-stuff/products/medium-cafe-bag Jill - Cricut 4 Maker Cricut 4 Maker - Sticker Kit  Marty - LiquidWorkSpace - https://apps.apple.com/us/app/liquidworkspace/id6775087546  Announcements Macstock X wrapped up for 2026 what a great event! Stay tuned for the Digital pass coming soon Digital Pass | Macstock Conference & Expo Our Host Dave Ginsburg is an IT professional supporting Mac, iOS and Windows users and shares his wealth of knowledge of iPhone, iPad, Apple Watch, Apple TV and related technologies. Visit the YouTube channel https://youtube.com/intouchwithios follow him on Mastodon @daveg65, , BlueSky @daveg65  and the show @intouchwithios   Our Co-Hosts Jeff Gamet is a podcaster, technology blogger, artist, and author. Previously, he was The Mac Observer's managing editor, and Smile's TextExpander Evangelist. You can find him on his blog Jeff Gamet - Mastadon @jgamet Pixelfed @jgamet@pixelfed.social and Bluesky @jgamet.bsky.social‬ Podcasts The Context Machine Podcast  Retro Rewatch Retro Rewatch His YouTube channel https://youtube.com/jgamet Buy his art! Jeff Gamet Art Marty Jencius, Ph.D., is a professor of counselor education at Kent State University, where he researches, writes, and trains about using technology in teaching and mental health practice. His podcasts include Vision Pro Files, The Tech Savvy Professor and Circular Firing Squad Podcast. Find him at jencius@mastodon.social  https://thepodtalk.net  Eric Bolden is into macOS, plants, sci-fi, food, and is a rural internet supporter. You can connect with him by email at eabolden@mac.com, on Mastodon at @eabolden@techhub.social, on his blog, Trending At Work, and as co-host on The Vision ProFiles podcast.   Jill McKinley works in enterprise software, server administration, and IT. A lifelong tech enthusiast, she started her career with Windows but is now an avid Apple fan. Beyond technology, she shares her insights on ai, nature, faith, and personal growth through her podcasts. Her content on YouTube at @smallstepswithai and follow her on X @NorthwoodsJill. Find all her work at http://jillfromthenorthwoods.com  Chuck Joiner is the host of MacVoices and hosts video podcasts with influential members of the Apple community. Make sure to visit macvoices.com and subscribe to his podcast. You can follow him on Twitter @chuckjoiner and join his MacVoices Facebook group.

Can your smartphone become part of your mental health treatment? Prescription digital therapeutics (PDTs) promise to do exactly that — but what are they, and do they actually work? In this episode, host Gabe Howard is joined by ADAA member experts John Torous, MD, MBI, a digital psychiatry expert, and Michelle A. Patriquin, PhD, ABPP, a clinical psychologist, to separate hype from reality. Together, they explain what PDTs are — and aren't — and how mental health apps fit into modern treatment. The conversation explores how apps can help bridge long wait times for therapy; reinforce skills learned in treatment; track mood, sleep, and behavior between appointments; and provide valuable insights that improve conversations with mental health clinicians. Listeners will learn: the difference between FDA-approved mental health apps and standard wellness apps why choosing the "best" mental health app is less important than finding one you'll actually use consistently how to avoid common misconceptions about digital mental health tools and make informed choices  If you've ever opened an app store looking for mental health support, this episode will help you separate marketing from evidence so you can make smarter, safer, and more informed decisions about incorporating technology into your mental health care. This episode has been sponsored by the Anxiety and Depression Association of America (ADAA). Our guest, Dr. Michelle Patriquin, is the John S. Dunn Distinguished Professor and Associate Professor in Psychiatry and Behavioral Sciences at McGovern Medical School at UTHealth Houston, and serves as Assistant Dean of Digital Health & Innovation in the UTHealth Houston School of Behavioral Sciences. She is also Co-Director of Research for the John S. Dunn Behavioral Sciences Center, the largest academic inpatient psychiatric hospital in the United States. She is a board-certified clinical psychologist and researcher focused on digital mental health: bringing data-driven, tech-enabled mental health care into real-world clinical setting - especially intensive and inpatient mental healthcare - to improve safety, recovery, and access. Her work is widely published and is supported by state, federal, and foundation funding.  Our guest, John Torous, MD, MBI, is director of the digital psychiatry division in the Department of Psychiatry at Beth Israel Deaconess Medical Center (BIDMC), a Harvard Medical School-affiliated teaching hospital, where he also serves as a staff psychiatrist and associate professor.  He has a background in electrical engineering and computer sciences and received an undergraduate degree in the field from UC Berkeley before attending medical school at UC San Diego. He completed his psychiatry residency, fellowship in clinical informatics, and master's degree in biomedical informatics at Harvard. Dr. Torous is active in investigating the potential of mobile mental health and AI technologies for psychiatry, and his team supports mindapps.org as the largest database of mental health apps, mindApps.ai for benchmarking AI chatbots,  mindLAMP technology platform for scalable digital phenotyping and interventions, and the Digital Navigator program to promote digital equity and access. Dr. Torous has published over 300 peer reviewed articles and 5 book chapters on the topic. He directs the Digital Psychiatry Clinic at BIDMC which seeks to improve access to and quality of mental health care through augmenting treatment with digital innovations. Dr. Torous serves as editor-in-chief for the journal JMIR Mental Health, web editor for JAMA Psychiatry, and a member of various American Psychiatric Association committees.

Alzheimer's disease can begin developing years before memory and thinking problems become noticeable. Iris Broce-Diaz, Ph.D., of UC San Diego is developing accessible, noninvasive, and cost-effective tools to help primary care physicians and neurologists identify people at higher risk earlier. Her models combine information from cognitive assessments, brain imaging, genetics, and PET scans to estimate the likelihood that mild cognitive impairment will progress within five years. Combining multiple measures improves the models' ability to separate higher- and lower-risk patients. Broce-Diaz also plans to add women-specific factors, including menopause history, hormone therapy, reproductive history, endocrine markers, and symptoms. The goal is to support better referrals, guide monitoring, and help eligible patients consider treatment sooner. Earlier risk assessment could also strengthen clinical trials and make dementia care more useful across different health systems. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41632]

Alzheimer's disease can begin developing years before memory and thinking problems become noticeable. Iris Broce-Diaz, Ph.D., of UC San Diego is developing accessible, noninvasive, and cost-effective tools to help primary care physicians and neurologists identify people at higher risk earlier. Her models combine information from cognitive assessments, brain imaging, genetics, and PET scans to estimate the likelihood that mild cognitive impairment will progress within five years. Combining multiple measures improves the models' ability to separate higher- and lower-risk patients. Broce-Diaz also plans to add women-specific factors, including menopause history, hormone therapy, reproductive history, endocrine markers, and symptoms. The goal is to support better referrals, guide monitoring, and help eligible patients consider treatment sooner. Earlier risk assessment could also strengthen clinical trials and make dementia care more useful across different health systems. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41632]

Alzheimer's disease can begin developing years before memory and thinking problems become noticeable. Iris Broce-Diaz, Ph.D., of UC San Diego is developing accessible, noninvasive, and cost-effective tools to help primary care physicians and neurologists identify people at higher risk earlier. Her models combine information from cognitive assessments, brain imaging, genetics, and PET scans to estimate the likelihood that mild cognitive impairment will progress within five years. Combining multiple measures improves the models' ability to separate higher- and lower-risk patients. Broce-Diaz also plans to add women-specific factors, including menopause history, hormone therapy, reproductive history, endocrine markers, and symptoms. The goal is to support better referrals, guide monitoring, and help eligible patients consider treatment sooner. Earlier risk assessment could also strengthen clinical trials and make dementia care more useful across different health systems. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41632]

Alzheimer's disease can begin developing years before memory and thinking problems become noticeable. Iris Broce-Diaz, Ph.D., of UC San Diego is developing accessible, noninvasive, and cost-effective tools to help primary care physicians and neurologists identify people at higher risk earlier. Her models combine information from cognitive assessments, brain imaging, genetics, and PET scans to estimate the likelihood that mild cognitive impairment will progress within five years. Combining multiple measures improves the models' ability to separate higher- and lower-risk patients. Broce-Diaz also plans to add women-specific factors, including menopause history, hormone therapy, reproductive history, endocrine markers, and symptoms. The goal is to support better referrals, guide monitoring, and help eligible patients consider treatment sooner. Earlier risk assessment could also strengthen clinical trials and make dementia care more useful across different health systems. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41632]

Alzheimer's disease can begin developing years before memory and thinking problems become noticeable. Iris Broce-Diaz, Ph.D., of UC San Diego is developing accessible, noninvasive, and cost-effective tools to help primary care physicians and neurologists identify people at higher risk earlier. Her models combine information from cognitive assessments, brain imaging, genetics, and PET scans to estimate the likelihood that mild cognitive impairment will progress within five years. Combining multiple measures improves the models' ability to separate higher- and lower-risk patients. Broce-Diaz also plans to add women-specific factors, including menopause history, hormone therapy, reproductive history, endocrine markers, and symptoms. The goal is to support better referrals, guide monitoring, and help eligible patients consider treatment sooner. Earlier risk assessment could also strengthen clinical trials and make dementia care more useful across different health systems. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41632]

Alzheimer's disease can begin developing years before memory and thinking problems become noticeable. Iris Broce-Diaz, Ph.D., of UC San Diego is developing accessible, noninvasive, and cost-effective tools to help primary care physicians and neurologists identify people at higher risk earlier. Her models combine information from cognitive assessments, brain imaging, genetics, and PET scans to estimate the likelihood that mild cognitive impairment will progress within five years. Combining multiple measures improves the models' ability to separate higher- and lower-risk patients. Broce-Diaz also plans to add women-specific factors, including menopause history, hormone therapy, reproductive history, endocrine markers, and symptoms. The goal is to support better referrals, guide monitoring, and help eligible patients consider treatment sooner. Earlier risk assessment could also strengthen clinical trials and make dementia care more useful across different health systems. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41632]

Alzheimer's disease can begin developing years before memory and thinking problems become noticeable. Iris Broce-Diaz, Ph.D., of UC San Diego is developing accessible, noninvasive, and cost-effective tools to help primary care physicians and neurologists identify people at higher risk earlier. Her models combine information from cognitive assessments, brain imaging, genetics, and PET scans to estimate the likelihood that mild cognitive impairment will progress within five years. Combining multiple measures improves the models' ability to separate higher- and lower-risk patients. Broce-Diaz also plans to add women-specific factors, including menopause history, hormone therapy, reproductive history, endocrine markers, and symptoms. The goal is to support better referrals, guide monitoring, and help eligible patients consider treatment sooner. Earlier risk assessment could also strengthen clinical trials and make dementia care more useful across different health systems. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41632]

Neal sits down with Adam Jacobs, President of Xzōm, a San Diego company developing a near-patient platform for isolating and analyzing exosomes from a small blood sample in under 30 minutes.Exosomes are tiny particles released by living cells that carry proteins and genetic material. Researchers believe these particles could provide useful signals about disease earlier or more dynamically than some existing biomarkers. Xzōm is working to turn that science into a compact testing platform, using a disposable cartridge and a mobile-device interface.The company's initial focus is early pancreatic-cancer detection. Adam also discusses how the underlying platform could potentially be adapted for other areas - including sepsis, preeclampsia, transplant monitoring, and neurological conditions - by changing the biomarkers targeted by each assay. Those applications would require their own development, clinical validation, and regulatory pathways.Adam shares his unusual route to biotech: Torrey Pines High School, Cornell baseball, professional ball in Australia, a clothing brand, a yoga studio, and a consulting firm. He also explains how technology originating at UC San Diego eventually came back into his life, Xzōm's partnership-led development model, and the role data analysis may play in interpreting complex biological signals.Plus, Adam and Neal bond over a shared appreciation for Roberto's on Carmel Valley Road.Key topics* Isolating and analyzing exosomes on one chip in 30 minutes* Why exosomes catch disease earlier than DNA - “stage zero”* A point-of-care lab that runs on a cell phone* The difference between a versatile platform and a validated diagnostic test* From pancreatic cancer to sepsis, preeclampsia, and brain injury* How Xzōm works with clinical and commercial partners* Adam's path from pro baseball to biotech* Why AI on the back end makes the whole thing work* Giving back: showing up, not just writing checksLinks & resources* Xzōm* A Morning Inside Xzōm's Lab Connect on LinkedIn* Neal Bloom * Adam Jacobs This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit risingtidepartners.substack.com/subscribe

Dr. Pradeep K. Khosla, Chancellor of UC San Diego, joins Dr. JP Novin to discuss how artificial intelligence is reshaping higher education and what it will take for institutions to remain competitive in a rapidly changing world. Together, they explore AI's impact on the workforce, the growing importance of balancing technological innovation with human-centered learning, and why the humanities remain essential in preparing adaptable graduates. Chancellor Khosla also shares insights into leading one of the nation's largest public research universities, managing unprecedented institutional growth, and navigating the financial and strategic challenges facing higher education.

Men with non-obstructive azoospermia may undergo microscopic testicular sperm extraction, or mTESE, without knowing whether sperm will be found. Kun Tan, Ph.D., of UC San Diego explains how molecular semen analysis could provide a noninvasive way to predict the procedure's outcome. The assay uses stage-specific germ cell markers identified through single-cell RNA sequencing, then measures those markers in semen with qPCR. Because semen contains germ cells from different stages of sperm development, their molecular signals may reflect what is happening inside the testes. Tan shows how the assay predicts whether sperm retrieval was successful and can identify where sperm development may be blocked. The research could help couples planning IVF or ICSI avoid unnecessary surgery, reduce financial and emotional burdens, and receive more detailed information about male infertility before treatment. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41630]

Men with non-obstructive azoospermia may undergo microscopic testicular sperm extraction, or mTESE, without knowing whether sperm will be found. Kun Tan, Ph.D., of UC San Diego explains how molecular semen analysis could provide a noninvasive way to predict the procedure's outcome. The assay uses stage-specific germ cell markers identified through single-cell RNA sequencing, then measures those markers in semen with qPCR. Because semen contains germ cells from different stages of sperm development, their molecular signals may reflect what is happening inside the testes. Tan shows how the assay predicts whether sperm retrieval was successful and can identify where sperm development may be blocked. The research could help couples planning IVF or ICSI avoid unnecessary surgery, reduce financial and emotional burdens, and receive more detailed information about male infertility before treatment. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41630]

Men with non-obstructive azoospermia may undergo microscopic testicular sperm extraction, or mTESE, without knowing whether sperm will be found. Kun Tan, Ph.D., of UC San Diego explains how molecular semen analysis could provide a noninvasive way to predict the procedure's outcome. The assay uses stage-specific germ cell markers identified through single-cell RNA sequencing, then measures those markers in semen with qPCR. Because semen contains germ cells from different stages of sperm development, their molecular signals may reflect what is happening inside the testes. Tan shows how the assay predicts whether sperm retrieval was successful and can identify where sperm development may be blocked. The research could help couples planning IVF or ICSI avoid unnecessary surgery, reduce financial and emotional burdens, and receive more detailed information about male infertility before treatment. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41630]

Men with non-obstructive azoospermia may undergo microscopic testicular sperm extraction, or mTESE, without knowing whether sperm will be found. Kun Tan, Ph.D., of UC San Diego explains how molecular semen analysis could provide a noninvasive way to predict the procedure's outcome. The assay uses stage-specific germ cell markers identified through single-cell RNA sequencing, then measures those markers in semen with qPCR. Because semen contains germ cells from different stages of sperm development, their molecular signals may reflect what is happening inside the testes. Tan shows how the assay predicts whether sperm retrieval was successful and can identify where sperm development may be blocked. The research could help couples planning IVF or ICSI avoid unnecessary surgery, reduce financial and emotional burdens, and receive more detailed information about male infertility before treatment. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41630]

Archaeology can help communities understand environmental change, protect cultural heritage, and prepare for an uncertain climate future. Isabel C. Rivera-Collazo, Ph.D., of UC San Diego studies relationships among people, oceans, coastal ecosystems, and climate in Puerto Rico and the Caribbean. She explains how Hurricane Maria shifted her research from identifying theoretical vulnerabilities to supporting communities facing immediate risks. Her work combines archaeology with ecology, biology, geology, local histories, and community knowledge. Research on plants, fishing traditions, coral reefs, and coastal sites has supported sand dune restoration, heritage protection, and the creation of a marine protected area. Rivera-Collazo emphasizes that residents are experts on their own landscapes and should guide research priorities. Recovering knowledge from the past can strengthen identity, support ecosystem restoration, and help communities shape more resilient futures. Series: "Mi Universidad " [Science] [Education] [Show ID: 41490]

Archaeology can help communities understand environmental change, protect cultural heritage, and prepare for an uncertain climate future. Isabel C. Rivera-Collazo, Ph.D., of UC San Diego studies relationships among people, oceans, coastal ecosystems, and climate in Puerto Rico and the Caribbean. She explains how Hurricane Maria shifted her research from identifying theoretical vulnerabilities to supporting communities facing immediate risks. Her work combines archaeology with ecology, biology, geology, local histories, and community knowledge. Research on plants, fishing traditions, coral reefs, and coastal sites has supported sand dune restoration, heritage protection, and the creation of a marine protected area. Rivera-Collazo emphasizes that residents are experts on their own landscapes and should guide research priorities. Recovering knowledge from the past can strengthen identity, support ecosystem restoration, and help communities shape more resilient futures. Series: "Mi Universidad " [Science] [Education] [Show ID: 41490]

Do you use your imagination enough? Most parents think of imagination as something for playtime — a "nice to have" that fades once kids get older and life gets "serious." But Dr. Cassandra Vieten, director of science programs at the Arthur C. Clarke Center for Human Imagination at UC San Diego, joins Dr. Aliza Pressman to make the case that imagination is a trainable skill with real developmental and psychological weight. They unpack the connection between imagination and anxiety, why kids naturally live closer to the "field of possibility" than adults do, and how something as simple as a car-ride question can open up conversations that "how was your day?" never will. What You'll Learn: The real, physiological link between imagination and anxiety How to use your child's favorite fandom as a doorway into connection Strategies to turn discipline moments into imagination-building thought experiments How to use screens and social media for connection instead of "slot machine" scrolling

E-bike crashes and injuries in California are increasing, a new study out of UC San Diego finds. And those injuries are not only more severe compared with conventional bikes, they'redisproportionately involving kids age 14 and younger. We'll hear how doctors, lawmakers andbiking advocates are responding to the risks posed by e-bikes – and by what some call emotorcycles – and we'll hear your takes about how we can make our roads safer for all. Guests: Azul Dahlstrom-Eckman, reporter, KQED Asha Weinstein Agrawal, professor and researcher, Mineta Transportation Institute at San Jose State University John Maa, governor and former president, American College of Surgeons; former trauma surgeon, MarinHealth Medical Center; co-author of the new study from UCSD, “An exponential increase in e-bike injuries in California” Learn more about your ad choices. Visit megaphone.fm/adchoices

Message Dan and MikeWe're back from our first San Diego Comic-Con with press credentials, and this episode kicks off a two-part recap of the entire experience. Part one covers our arrival, the scramble to find the convention center on San Diego's trolley system, and the reality check that comes with picking up press badges for the first time. We also take a detour to Seaport Village for tacos and a beer with a view of the harbor, then head north to UC San Diego for a surprise highlight of the trip: Shredding the Multiverse, a concert reimagining television and film scores from shows like Cobra Kai, Spider-Man, and The Penguin with a full orchestra and rock energy.From there we walk through preview night, our first real taste of the exhibit hall, complete with two-hour lines, an ocean of vendors, and a candid discussion about what press credentials do and don't actually get you at a con this size. We get into a few Comic-Con-brain moments (yes, we coin the term), some sibling bickering about San Diego weather, and a genuinely strange arcade cabinet encounter that turns into its own little subplot.The back half of the episode dives into two of our favorite panels from day one. First, a look at the upcoming Lucas Museum of Narrative Art, opening in Los Angeles this September, and why it's a celebration of storytelling and visual art far beyond just Star Wars. Then we sit in on Brad Bird's career retrospective panel, tracing his path from The Iron Giant and The Incredibles to Mission: Impossible – Ghost Protocol and his surprising, nearly two-hundred-episode history with The Simpsons. Bird also previews his new animated sci-fi noir series Ray Gun and drops a small but exciting update on the status of Incredibles 3.It's an exhausting, funny, occasionally chaotic first day, and we haven't even gotten to Hall H yet. That's coming in part two, along with days two and three of the convention. Thanks for riding along with us on our first Comic-Con as press, sore feet and all.Support the showOh Brother Podcast:Support the Show! (Be The First to Listen with Early Access)Listen on all podcast platformsSubscribe on YouTubeFollow us on Instagram

Editor's Choice:  Biomarker heterogeneity and efficacy of durvalumab plus carboplatin/paclitaxel followed by durvalumab with or without olaparib in patients with mismatch repair proficient endometrial cancer: exploratory analyses of the DUO-E/GOG-3041/ENGOT-EN10 trialEditorial: Hitting the mark—or missing it? The promise and peril of biomarkers in endometrial cancerHosted by: Amanda Nickles Fader, MD; Johns Hopkins Medicine Baltimore, MD, USAFeaturing: Kathleen Moore, MD; Gynecologic Cancer Clinic, Stephenson Cancer Center at the University of Oklahoma Medical Center, Oklahoma City, OK, USARamez N Eskander, MD;  Department of Obstetrics, Gynecology and Reproductive Sciences, Division of Gynecologic Oncology, UC San Diego, USACheck out more content on the journal's homepage  at https://www.gynecologiconcology-online.net

Chronic pain in older adults can affect mobility, mood, sleep, social connection, and independence. Una Makris, M.D., M.Sc., UC San Diego and VA San Diego Healthcare System, explains why musculoskeletal pain is common later in life and why medications or procedures alone may not meet the needs of many patients. Drawing on her work in rheumatology and geriatrics, Makris describes how pain and depression can reinforce each other, making it important to address both together. She highlights an age-friendly behavioral coaching approach that uses motivational interviewing, values-based goal setting, physical activity, and social support to help people reconnect with meaningful activities. By focusing on small, safe increases in movement, this research points to practical ways to support better function, quality of life, and healthy aging. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41172]

Chronic pain in older adults can affect mobility, mood, sleep, social connection, and independence. Una Makris, M.D., M.Sc., UC San Diego and VA San Diego Healthcare System, explains why musculoskeletal pain is common later in life and why medications or procedures alone may not meet the needs of many patients. Drawing on her work in rheumatology and geriatrics, Makris describes how pain and depression can reinforce each other, making it important to address both together. She highlights an age-friendly behavioral coaching approach that uses motivational interviewing, values-based goal setting, physical activity, and social support to help people reconnect with meaningful activities. By focusing on small, safe increases in movement, this research points to practical ways to support better function, quality of life, and healthy aging. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41172]

Chronic pain in older adults can affect mobility, mood, sleep, social connection, and independence. Una Makris, M.D., M.Sc., UC San Diego and VA San Diego Healthcare System, explains why musculoskeletal pain is common later in life and why medications or procedures alone may not meet the needs of many patients. Drawing on her work in rheumatology and geriatrics, Makris describes how pain and depression can reinforce each other, making it important to address both together. She highlights an age-friendly behavioral coaching approach that uses motivational interviewing, values-based goal setting, physical activity, and social support to help people reconnect with meaningful activities. By focusing on small, safe increases in movement, this research points to practical ways to support better function, quality of life, and healthy aging. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41172]

Chronic pain in older adults can affect mobility, mood, sleep, social connection, and independence. Una Makris, M.D., M.Sc., UC San Diego and VA San Diego Healthcare System, explains why musculoskeletal pain is common later in life and why medications or procedures alone may not meet the needs of many patients. Drawing on her work in rheumatology and geriatrics, Makris describes how pain and depression can reinforce each other, making it important to address both together. She highlights an age-friendly behavioral coaching approach that uses motivational interviewing, values-based goal setting, physical activity, and social support to help people reconnect with meaningful activities. By focusing on small, safe increases in movement, this research points to practical ways to support better function, quality of life, and healthy aging. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41172]

Chronic pain in older adults can affect mobility, mood, sleep, social connection, and independence. Una Makris, M.D., M.Sc., UC San Diego and VA San Diego Healthcare System, explains why musculoskeletal pain is common later in life and why medications or procedures alone may not meet the needs of many patients. Drawing on her work in rheumatology and geriatrics, Makris describes how pain and depression can reinforce each other, making it important to address both together. She highlights an age-friendly behavioral coaching approach that uses motivational interviewing, values-based goal setting, physical activity, and social support to help people reconnect with meaningful activities. By focusing on small, safe increases in movement, this research points to practical ways to support better function, quality of life, and healthy aging. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41172]

Authentic autism representation begins with listening to autistic people and including them in stories about their lives. Seth Bakke, producer, writer and director of The Rescue, explains how his autistic cousin Aaron and a poem by autistic typer Peter Tran inspired the film. Bakke describes working with Aaron on screen, consulting the Tran family and adapting the set to support his needs. Autistic typers Otto Lana and Peter Tran, joined by Steven Tran, a postdoctoral researcher at UC San Diego, discuss where the film reflects their experiences, where it simplifies communication through typing and why creative freedom must remain grounded in lived experience. They address presuming competence, the difference between hearing and listening, and the need for autistic actors and advisers. Their participation challenges stereotypes and helps audiences see they should be full participants in their own stories. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Arts and Music] [Show ID: 41175]

Authentic autism representation begins with listening to autistic people and including them in stories about their lives. Seth Bakke, producer, writer and director of The Rescue, explains how his autistic cousin Aaron and a poem by autistic typer Peter Tran inspired the film. Bakke describes working with Aaron on screen, consulting the Tran family and adapting the set to support his needs. Autistic typers Otto Lana and Peter Tran, joined by Steven Tran, a postdoctoral researcher at UC San Diego, discuss where the film reflects their experiences, where it simplifies communication through typing and why creative freedom must remain grounded in lived experience. They address presuming competence, the difference between hearing and listening, and the need for autistic actors and advisers. Their participation challenges stereotypes and helps audiences see they should be full participants in their own stories. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Arts and Music] [Show ID: 41175]

Scientific progress depends on curiosity, investment and the freedom to take risks. Nobel Laureate and UC San Diego alumnus Fred Ramsdell traces his path from community college to biotechnology and a discovery that reshaped understanding of immune regulation. He explains how decades of publicly funded research made that breakthrough possible and why failed experiments are essential steps toward discovery. Ramsdell discusses threats to federal research funding, the private sector's limited tolerance for risk and the need for scientists to communicate clearly. Rebuilding trust, he argues, starts with listening, finding shared values and explaining how basic research leads to new treatments, economic value and national security. Sustained support for science matters because no one can predict where the next major breakthrough will begin. Series: "Deep Look Public Speaker Series" [Science] [Show ID: 41113]

Hear from two experts in osteoporosis as they introduce the Osteoporosis Action Network—a volunteer coalition of osteoporosis leaders and industry partners focused on redefining the standard of care in osteoporosis, with a bold ambition of preventing 3 million fractures by 2033. Rita Roy, MD, CEO, National Spine Health Foundation will discuss the coalition's mission and vision, while Susan Bukata, MD, Professor and Chair, Department of Orthopaedics, UC San Diego, will discuss the motivation behind the creation of the coalition and share her experience with post-fracture care programs. Listeners will gain insights into action they can take to get post-fracture care programs off the ground and close care gaps. Dr. Roy and Dr. Bukata are paid consultants for Amgen. Initial support for Osteoporosis Action Network provided by Amgen.This episode is sponsored by Amgen.

First, the DOJ has accused UC San Diego of racial discrimination. Then, we'll tell you why a billion dollars in medicaid reimbursements is being withheld. Also, a request to raise SDG&E rates is being opposed by some. And, we'll tell you how you can be involved with Comic-Con without having a badge.

In this episode we speak with Alon Goren from UC San Diego about his work at the intersection of genomic technology development and chromatin biology. We discuss how his lab studies how the epigenome is regulated, how disruption of that regulation contributes to disease, and how technology can be improved to make results more robust and reproducible. We talk about his early interest in biology, how that developed through medical research training, and how a molecular biology lab shaped the direction of his career. He explains how curiosity about how cells and organisms work led him toward genomics and chromatin research. We then discuss several methods from his career, including early direct sequencing approaches for small amounts of DNA and RNA, ChIP-based methods for chromatin regulators, and work on improving ChIP-seq workflows. He explains why antibody choice matters, why monoclonal antibodies can improve reproducibility, and how automation helped scale the process. We also cover his work on spike-in normalization, including the risks of using exogenous chromatin incorrectly and the need for better safeguards in genome-wide comparisons. He describes a newer approach that uses two spike-ins to provide multiple checks on normalization. Finally, we discuss his work on short tandem repeats, zebrafish heart regeneration, and SIRT6-related polymerase pausing, as well as a newer platform that converts molecular interactions into sequencing-readable barcodes. He closes by stressing the importance of validation, careful protocol design, and methods that can be used reliably by multiple people. References Ram, O., Goren, A., Amit, I., Shoresh, N., Yosef, N., Ernst, J., Kellis, M., Gymrek, M., Issner, R., Coyne, M., Durham, T., Zhang, X., Donaghey, J., Epstein, C. B., Regev, A., & Bernstein, B. E. (2011). Combinatorial patterning of chromatin regulators uncovered by genome-wide location analysis in human cells. Cell, 147(7), 1628–1639. https://doi.org/10.1016/j.cell.2011.09.057 Busby, M., Xue, C., Li, C., Farjoun, Y., Gienger, E., Yofe, I., Gladden, A., Epstein, C. B., Cornett, E. M., Rothbart, S. B., Nusbaum, C., & Goren, A. (2016). Systematic comparison of monoclonal versus polyclonal antibodies for mapping histone modifications by ChIP-seq. Epigenetics & chromatin, 9, 49. https://doi.org/10.1186/s13072-016-0100-6 Patel, L. A., Cao, Y., Mendenhall, E. M., Benner, C., & Goren, A. (2024). The Wild West of spike-in normalization. Nature biotechnology, 42(9), 1343–1349. https://doi.org/10.1038/s41587-024-02377-y Ben-Yair, R., Butty, V. L., Busby, M., Qiu, Y., Levine, S. S., Goren, A., Boyer, L. A., Burns, C. G., & Burns, C. E. (2019). H3K27me3-mediated silencing of structural genes is required for zebrafish heart regeneration. Development (Cambridge, England), 146(19), dev178632. https://doi.org/10.1242/dev.178632 Patel, L., Cao, Y., Xu, T., Modolo, E., Dishon, T., Zhang, L., Mendenhall, E., Heinz, S., Simon, I., Benner, C., & Goren, A. (2025). Improved spike-in normalization clarifies the relationship between active histone modifications and transcription. Genomics. https://doi.org/10.1101/2025.11.25.690627 Xu, T., Wang, J., Shin, Y., Cao, Y., Zhang, L., Modolo, E., Dishon, T., Fisher, J., Norton, M., Fry, C. J., Farjoun, Y., Mendenhall, E., Heinz, S., Benner, C., & Goren, A. (2026). Multiplexed measurements of protein-protein interactions and protein abundance across cellular conditions using Prod&PQ-seq. Genomics. https://doi.org/10.64898/2026.01.01.697286 Related Episodes Taking ChIP from Yeast to ENCODE to Enable Genome-Wide Regulatory Protein Mapping (Peggy Farnham) Comparing CUT&Tag to ENCODE ChIP-Seq in Alzheimer's Disease Samples (Sarah Marzi) Chromatin Profiling: From ChIP to CUT&RUN, CUT&Tag and CUTAC (Steven Henikoff) Contact Epigenetics Podcast on Mastodon Epigenetics Podcast on Bluesky Dr. Stefan Dillinger on LinkedIn Active Motif on LinkedIn Active Motif on Bluesky Email: podcast@activemotif.com

A completed, unpublished Dr. Seuss manuscript was recently discovered in author Theodor Geisel's archives at UC San Diego. How was the book found, and what does it reveal about the author's creative process and complicated legacy? USA TODAY Books Reporter Clare Mulroy joins The Excerpt to share her reporting.Plus, watch "Sing the 50 United States" written by Dr. Seuss.Let us know what you think of this episode by sending an email to podcasts@usatoday.com. Episode transcript available here. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

From co-managing the Odwalla IPO at Van Kasper & Company to raising $100 million with Lehman Brothers for a Pacific Northwest workers comp captive when insurance was unavailable at any price, David Horwich shares why thinking like a buyer, understanding the three ways to grow a business, and building optionality matter more than chasing any specific exit. In this episode of the DealQuest Podcast, host Corey Kupfer sits down with David Horwich, the founder of Horwich Strategic Advisors (HSA) in Los Angeles. David spent 13 years at Van Kasper & Company before its 1999 sale, retired from banking in 2010, and spent nearly nine years at GHJ before spinning out his own firm about a year ago. Across his four decade career he has been exposed to somewhere between 5,000 and 5,500 companies. WHAT YOU'LL LEARN: Why running a market check with five investment banking firms and five private equity groups produces a real world valuation, how the three ways to grow apply to almost any company, and why selling new stuff to existing customers is by far the easiest path. David also shares how the workers comp captive he raised $100 million for is still operating today. DAVID'S JOURNEY: After economics at UC San Diego and an MBA at Berkeley, David spent five years at a transportation equipment leasing business in San Francisco. He then joined Bruce Emeluth as the first hire at Van Kasper & Company, where he stayed 13 years and chaired the firm's fairness opinion committee. Van Kasper was sold in 1999 to a bank out of Salt Lake City that Wells Fargo later acquired, making the group the first incarnation of Wells Fargo Securities in the fall of 2000. David left in 2003, retired from banking in 2010, spent nearly nine years at GHJ, and spun out Horwich Strategic Advisors about a year ago. KEY INSIGHTS: Not all revenue is created equal. Repeatable revenue beats one-off revenue. Higher margin beats lower margin. Revenue that requires no working capital beats revenue that ties it up. Most owners street fight for the next million dollars of revenue without asking whether it is good revenue or bad. There are three ways to grow a business and the second is easiest by far. Sell what you have to more customers. Sell new stuff to existing customers. Sell new stuff to new customers. David is emphatic that you should almost never attempt the third. Existing customers have already crossed the Rubicon with you, so every cost is lower. Build optionality before you build an exit plan. Before running any analysis for owners unsure what to do, David sends them to their investment advisor to get their financial goals clear first. Then he outlines every alternative. Keep it. Sell it. Recapitalize it. Gift some but not all. The toolkit is small, but choosing well requires clarity first. Perfect for privately held business owners who want to know what their company is actually worth, entrepreneurs weighing whether to buy or build, and leaders in a transition moment who need optionality before an exit. FOR MORE ON THIS EPISODE: https://www.coreykupfer.com/blog/davidhorwich FOR MORE ON DAVID HORWICH: Website: https://horwichadvisors.com LinkedIn: https://www.linkedin.com/in/david-horwich-9317b56/ FOR MORE ON COREY KUPFER https://www.linkedin.com/in/coreykupfer/ https://www.coreykupfer.com/ Corey Kupfer is an expert strategist, negotiator, and dealmaker. He has more than 35 years of professional deal-making and negotiating experience. Corey is a successful entrepreneur, attorney, consultant, author, and professional speaker. He is deeply passionate about deal-driven growth. He is also the creator and host of the DealQuest Podcast. Get deal-ready with the DealQuest Podcast with Corey Kupfer, where like-minded entrepreneurs and business leaders converge, share insights and challenges, and success stories. Equip yourself with the tools, resources, and support necessary to navigate the complex yet rewarding world of dealmaking. Dive into the world of deal-driven growth today! Episode Highlights with Timestamps [00:00:00] - Introduction and overview [00:02:42] - Chairman's bag carrier and the waste coal project in Hardin, Montana[00:06:22] - Joining Bruce Emeluth as first hire at Van Kasper & Company [00:11:52] - The Odwalla IPO at $8 a share and the E. coli tragedy [00:24:11] - Exposure to somewhere between 5,000 and 5,500 companies [00:35:26] - The market check and the four questions [00:48:00] - The $100 million workers comp captive with Lehman Brothers[00:50:41] - What freedom means to David Guest Bio David Horwich is the founder of Horwich Strategic Advisors (HSA), a Los Angeles based firm focused on maximizing the value of privately held businesses. He runs market checks that produce real world valuations, builds strategic growth plans, and helps owners think like buyers before any transaction. He has been exposed to somewhere between 5,000 and 5,500 companies across his four decade career. After economics at UC San Diego and an MBA at Berkeley, David spent five years at a transportation equipment leasing business in San Francisco before joining Bruce Emeluth as the first hire at Van Kasper & Company, where he stayed 13 years. Van Kasper was sold in 1999 and became the first incarnation of Wells Fargo Securities in the fall of 2000. David retired from banking in 2010, spent nearly nine years at GHJ, and spun out his own practice about a year ago. Host Bio Corey Kupfer is an expert strategist, negotiator, and dealmaker with more than 35 years of professional deal-making and negotiating experience. Corey is a successful entrepreneur, attorney, consultant, author, and professional speaker deeply passionate about deal-driven growth. He is the creator and host of the DealQuest Podcast. Show Description Do you want your business to grow faster? The DealQuest Podcast with Corey Kupfer reveals how successful entrepreneurs and business leaders use strategic deals to accelerate growth. From large mergers and acquisitions to capital raising, joint ventures, strategic alliances, real estate deals, and more, this show discusses the full spectrum of deal-driven growth strategies. Get the confidence to pursue deals that will help your company scale faster. Related Episodes Episode 330 - Pete Mohr: Building an exit-ready business and understanding what your company is actually worth Episode 332 - John Martinka: Exit with style, grace, and more money Episode 293 - Sunny Vanderbeck: Long horizon value creation and building businesses that deserve to last Episode 350 - Tom Dillon: Capital strategy, alternative funding sources, and when not to take venture money Social Media Follow DealQuest Podcast: LinkedIn: https://www.linkedin.com/in/coreykupfer/ Website: https://www.coreykupfer.com/ Follow David Horwich: Website: https://horwichadvisors.com LinkedIn: https://www.linkedin.com/in/david-horwich-9317b56/ Keywords/Tags investment banking, growth consulting, exit planning, market check, three ways to grow a business, think like a buyer, enterprise value, middle market M&A, Van Kasper & Company, Odwalla IPO, private equity, capital raising, business valuation, optionality, strategic growth planning, buy versus build, workers comp captive, privately held businesses, Los Angeles M&A advisor, deal-driven growth