University of California Audio Podcasts (Audio)

Experts discuss recent advances in how maternal health and immune function during pregnancy affect infant development and long-term outcomes. Research focuses on immune adaptations, complications like preterm birth, and neuroimmune pathways, using techniques such as mass cytometry, spatial proteomics, and chemogenetics to identify biomarkers and mechanisms that guide prevention and treatment strategies. Sandy Ramos, M.D. Clinical Landscape and OGRS Opportunities Louise Laurent, M.D.,Ph.D. Single-Cell and Spatial Multi-Omic Insights into the Human Placenta (HUBMAP) Marni Jacobs, Ph.D. The MOM-Health Study and the MOHD Consortium Lars Bode, Ph.D. Human Milk Institute (HMI) Gretchen Bandoli, Ph.D. MotherToBaby Ina Stelzer, Ph.D. Reproductive Immunology Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40666]

As part of our Earth Serenade series, we present Earth Motets, a glorious feature-length movie made for BachFest, the annual gathering of musicians and fans in Bach's hometown of Leipzig, Germany. The music is performed by Solomon's Knot paired with images taken by astronauts Butch Wilmore, Don Pettit, Nicole Mann and Jeanette Epps aboard the International Space Station. Series: "Arts Channel " [Arts and Music] [Show ID: 40871]

Explore key aspects of aging and menopause, focusing on women's health and how biological changes impact overall well-being. Experts discuss current research on healthy aging, including the role of physical activity, brain health, and hormone changes during menopause. They highlight how sex differences affect diseases like Alzheimer's and emphasize the importance of personalized approaches to treatment and prevention. The presentation also underscores ongoing studies and resources aimed at improving the quality of life for aging women through better understanding and support Linda Brubaker, M.D.,M.S. Clinical Landscape and OGRS Opportunities Amanda Lewis, Ph.D. Glycobiology (GLOW) Andrea LaCroix, Ph.D. Healthy Aging After Menopause Anthony Molina, Ph.D. Stein Institute for Research on Aging Sarah Banks, Ph.D. Alzheimer in Women Emily Lukacz, M.D.,M.A.S. Prevention of Lower Urinary Tract Symptoms (PLUS) Research Consortium and Pelvic Floor Disorders Network (PFDN) Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40668]

The "energy transition" is actually a shift from relying on fossil fuels (like coal, oil, and gas) to using metals to generate energy. However, extracting metals has always been a significant environmental and political issue, especially for cities. This problem has been around for centuries, even ancient Roman writers wrote about it. In this program, Helen Thompson, Professor of Political Economy at Cambridge University, talks about the historic use of fossil fuels and its economic, social and environmental impacts to the transition today to extracting metals for energy, dominated by China. Thompson points out that extracting resources will always have environmental and social costs. To mitigate these risks, she says we need to find ways to reduce international competition and ecological damage. This requires acknowledging that the idea of endless progress, which was fueled by fossil fuels, has its limits. And she says we must prioritize sustainability and responsible resource management to create a better future. Series: "UC Berkeley Graduate Lectures" [Public Affairs] [Business] [Show ID: 40428]

Menstruation is the cyclical shedding of the endometrium triggered by falling progesterone levels. Menstruation is a rare trait found in less than 2% of mammals and likely evolved independently at least 4 times. Why do some mammals menstruate while most do not? The leading hypothesis is that menstruation occurs as a nonadaptive consequence of spontaneous decidualization of the endometrium, which evolved to increase biosensoring of embryo quality. While the trait of spontaneous decidualization (and as a byproduct, menstruation) was likely shaped by natural selection, menstruation also disposes women to conditions such as endometriosis, pre-menstrual syndrome, and bleeding disorders, especially in the contemporary context. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40693]

Filmmaker Adamu Chan joins UC Santa Barbara's Althea Wasow for a powerful conversation about "What These Walls Won't Hold", a documentary he created while incarcerated at San Quentin during the COVID-19 pandemic. The film, which aired nationally on PBS's "America ReFramed", captures the resilience and activism of incarcerated people and their communities in the face of crisis. Chan shares how filmmaking became a tool for resistance and healing, offering an inside look at life behind bars. This discussion explores the film's creative process, its social justice impact, and the importance of centering incarcerated voices. It's an inspiring program about storytelling, humanity, and the power of community—even in the most challenging circumstances. Series: "Carsey-Wolf Center" [Humanities] [Show ID: 40540]

In this program, Dr. Sean Spencer explores the healthy way in which carbohydrates are digested throughout the body. To understand this concept Dr. Spencer discusses the difference between digesting simple sugars and complex carbohydrates.   Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 40774]

William Lowry, Ph.D., discusses manipulating metabolic pathways in hair follicle stem cells to inhibit tumorigenesis. By blocking glycolysis and glutamine lysis simultaneously, they observed tumor regression, highlighting the complex interplay between metabolism and cancer. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39256]

As part of our Earth Serenade series, we present music by Dwayne Haggins & Friends to accompany these beautiful images of Earth taken by the crew of ISS 65. The song "I Get Sad" evokes honest emotions as we watch the dancing aurora and night clouds. “Where it Wants” follows rivers, mountains and a hurricane. Series: "Arts Channel " [Arts and Music] [Show ID: 40873]

Experts highlight innovative research and clinical advances in fertility and infertility. Speakers share new ways to improve IVF outcomes using liquid biopsy and RNA analysis, aiming to predict embryo quality without invasive tests. They also explore how imaging technologies can better detect and monitor reproductive cancers, helping tailor treatments for conditions like ovarian and cervical cancer. Throughout, there's a focus on addressing health disparities, improving care for all genders, and using big data and AI to personalize reproductive health solutions. Antoni Duleba, M.D. Clinical Landscape and OGRS Opportunities Rebecca Rakow Penner, M.D.,Ph.D. Imaging in Gynecologic Disorders Jennifer Anger, M.D.,M.P.H. Interstitial Cystitis/Bladder Pain Syndrome in Reproductive Age Women Sheng Zhong, Ph.D. Silverseq and Liquid Biopsy Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40667]

Pressures of life on Earth experienced by our ancestors – as multicellular beings, as hosts to parasites, and as home to microbes – shaped the evolved structure and function of our immune systems.  Some of the traits favored by natural selection have conferred resistance against infections while opening vulnerabilities to autoimmune diseases.  I will illustrate why analysis of the deep-time origins of mammalian immune systems reveals general principles of optimal defense and helps to explain why hosts are so profoundly variable in their susceptibility to infectious and inflammatory diseases. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40692]

Superradiance: Embodying Earth is a multiscreen video and sound installation by artists Memo Akten and Katie Peyton Hofstader that serves as a centerpiece of Embodied Pacific: Oceans Unseen. Learn how collaboration-inspired immersive displays engage us and shape our understanding and appreciation of the ocean's unseen mysteries. The Birch Aquarium hosts this Jeffery B. Graham Perspectives on Ocean Science Lecture Series for a conversation with the artists as they describe how they use art to engage us in science, evoking a visceral and intimate connection to our living planet! Series: "Jeffrey B. Graham Perspectives on Ocean Science Lecture Series" [Science] [Show ID: 40593]

The Carsey-Wolf Center welcomes Jeff Bridges and Amy Brenneman, the award-winning stars of The Old Man, for a conversation with director/writer/producer Brad Silberling. Bridges and Brenneman share their creative perspectives on the series' treatment of aging and discuss other aspects of their unique collaboration. Series: "Carsey-Wolf Center" [Humanities] [Show ID: 40544]

Curious about the secret to staying young? Rob Signer shares insights into how our bodies age, focusing on the role of stem cells and a critical protein called HSF1 that helps them cope with stress. Signer explores the delicate balance of keeping these cells healthy without increasing cancer risk and highlighted some promising progress in enhancing the cells' ability to manage waste. Series: "Excerpts" [Health and Medicine] [Show ID: 40775]

How arrogant of humans to think we make the only music! As we fly over the Pacific coast of California and Mexico, let's listen to the sounds of whales, dolphins, snapping shrimp and more, recorded in those same waters. The view from above comes from the astronauts of ISS 53. The sounds from below courtesy of the Laguna San Ignacio Ecosystem Science Program, Macaulay Library of Cornell University, Monterey Bay Aquarium Research Institute and Ocean Networks of Canada. Earth as one harmonious symphony of life! Series: "Earth Serenade" [Arts and Music] [Show ID: 40863]

Cancer is normal development spun out of control. It is the great plasticity and power of development, without the overarching controls that guide normal development toward an integrated adult form. Instead, whenever a newly developed kind of tissue acquires the ability to survive, grow, and resist control, there is nothing to stop it. That may be why normal adult cells are often terminally differentiated into a restricted cellular program. And it may be why wound healing, which releases the restricted cellular program and powerfully plastic tissue remodeling, is so tightly regulated and, when dysregulated, so often associates with cancer. With regard to evolutionary history, humans develop differently from their ape ancestors, and their lifestyle causes them to suffer different kinds of tissue damage. Those differences in development and wound healing likely led to new aspects of cancer disease over human history. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40691]

The human body has traits that evolved at different times, from 1.5 billion to 2 million years ago, each bringing health benefits and risks. Multicellularity enabled organs and cancer. The immune system defends us but can cause inflammation. Breastfeeding supports infant health but relates to breast cancer risk. Menstruation and invasive placentas improved reproduction but led to pain and cancer risks. Human-specific traits like bipedalism and aging brought new issues like back pain and childbirth problems. Hair loss and sweat glands helped us stay cool but increased skin cancer risk. Our hunter-gatherer past shaped our microbiome and health, but also made us prone to modern diseases from lifestyle changes. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40701]

As part of the 2025 Developmental Disabilities Conference, Dr. Adiaha Spinks-Franklin provides a brief overview of fetal alcohol spectrum disorder. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 40608]

In this excerpt, Dr. Natalie Marshall discusses the central importance of exercise to improve chromosomal and telomere health. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 40683]

The Moon and Back is the directorial debut of UCSB Film and Media Studies alumnus Leah Bleich. The Carsey-Wolf Center was proud to welcome Leah back to campus for a discussion of her film with UCSB moderator Ross Melnick. Series: "Carsey-Wolf Center" [Humanities] [Show ID: 40543]

Fadel Zeidan, Ph.D., discusses the science of mindfulness and how meditation can change the brain. He explains what happens in the brain during stress, how mindfulness helps us become more self-aware, and why it's important to pay attention on purpose. Zeidan shares easy ways to bring mindfulness into daily life, even in small moments. The video includes guided meditations led by Zeidan. Viewers can follow along as he teaches simple breathing techniques and short practices designed to build focus and calm the nervous system. Whether you're new to meditation or looking to deepen your practice, this program offers useful tools backed by science. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40267]

In our latest Earth Serenade, enjoy this orbital 6,000 mile journey at dawn from the Atlantic Ocean to the Bay of Bengal. We pass over Europe, Asia and India, to dusk over Bay of Bengal courtesy of the crew of the ISS 40. The beautiful music of Bach's Toccata and Fugue in F Major is performed by Laura Bottei in her official Master of Music Recital on the Fisk organ at Indiana University. Series: "Earth Serenade" [Arts and Music] [Show ID: 40787]

Yaron Singer, Vice President of AI and Security at Cisco, co-founded a company specializing in artificial intelligence solutions, which was acquired by Cisco in 2024. They developed a firewall for artificial intelligence, a tool designed to protect AI from making critical mistakes. No matter how sophisticated AI is, errors can still happen, and these errors can have far-reaching consequences. The product is designed to detect and fix such mistakes. This technology was developed long before ChatGPT and its competitors burst onto the scene, making it the hottest industry in tech investment. Join Singer as he sits down with UC San Diego professor Mikhail Belkin to discuss his work and the continued effort to make artificial intelligence secure. Series: "Data Science Channel" [Science] [Show ID: 40265]

As part of the 2025 Developmental Disabilities Conference, Sneha Dave talks about future healthcare as young adults with chronic and rare medical conditions grow older. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 40606]

As part of the 2025 Developmental Disabilities Conference, Season Goodpasture, Founder and Executive Director, Acorns to Oak Trees, talks about improving access and equity in tribal communities. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 40607]

Dr. Terence Friedlander reviews the various patient outcomes after hip fracture surgery. Series: "Excerpts" [Health and Medicine] [Show ID: 40752]

The risk for many chronic diseases is directly linked to metabolic changes in the body and loss of muscle mass often associated with aging. In this excerpt, Dr. Natalie Marshall focuses on the role that muscles play in the body. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 40685]

Imagine early civilizations - Roman, Greek, Egyptian and more – exploring the Mediterranean. How magical that we can see it all from orbit today in this perfectly timed flight path by astronaut and photographer Butch Wilmore from an extended stay on the ISS. Musician Randy Souviney created this timeless music with his electric guitar and wizardry in the recording studio as he watched this Earth flight. This movie is dedicated to America's first female astronaut Sally Ride. Series: "Earth Serenade" [Arts and Music] [Show ID: 40776]

As part of the 2025 Developmental Disabilities Conference, Amy Westling and Melissa Drake discuss the plan for developmental services from CalHHS and DDS. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 40605]

Dr. Terence Friedlander discusses common issues brought on by osteoporosis. Series: "Excerpts" [Health and Medicine] [Show ID: 40751]

Metamaterials are special structures made of tiny components that give them unique electromagnetic properties not found in nature. One key feature is a negative refractive index, which enables technologies like "superlenses" for ultra-detailed imaging and "invisibility cloaks." The concept began when Sir John Pendry theorized special rings (SRRs) that could manipulate electromagnetic waves. Later, Sheldon Schultz and David Smith proved this idea with real experiments. Since then, research on metamaterials has rapidly expanded, covering everything from microwaves to visible light. In this talk, Professors Pendry and Smith will share their experiences and discuss how metamaterials have shaped science and technology over the past 25 years. Series: "Kyoto Prize Symposium" [Science] [Show ID: 40534]

In collaboration with the Transnational Italian Studies Program, the Carsey-Wolf Center presents a discussion examining the long history of Black African life in Italy with filmmakers Daphne Di Cinto and Medhin Paolos and UCSB moderator Stephanie Malia Hom. They discuss the short films Il Moro and Asmarina. Series: "Carsey-Wolf Center" [Humanities] [Show ID: 40541]

Dr. Sean Spencer talks about the vast microbial world that lives within our guts — known as the gut microbiome — and how it supports our health. Dr. Spencer emphasizes the importance of a high-fiber diet in creating a healthy gut microbiome which increases overall health. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 40761]

As part of our Earth Serenade series, we honor French organist and Bach specialist Andre Isoir, who died in 2016. Working with Isoir's son, Daniel, we bring you this lovely and serene Fantasia and Fugue in C minor, by Carl Philipp Emmanual Bach, the son of Johann Sebastian Bach. Cinematography by astronauts on Expeditions 71 aboard the International Space Station in 2024. It's a magical journey and tribute to Andre Isoir. Series: "Earth Serenade" [Arts and Music] [Show ID: 40758]

As part of the 2025 Developmental Disabilities Conference, Aaron Carruthers, Executive Director of the California State Council on Developmental Disabilities, talks about the journey of moving forward after the COVID-19 pandemic. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 40604]

The 3rd Annual Global Astrobiotechnology Hub focuses on advancing the intersection of space exploration, biotechnology, and innovation. The program brings together scientists, researchers, and space professionals to discuss how space technologies can accelerate scientific breakthroughs, particularly in fields like personalized medicine and bioengineering. Key themes include the challenges of conducting real-time research in space, the need for specialized astronaut-scientists, and the potential of space for groundbreaking experiments, such as organoid growth and in-space manufacturing. Experts underscore the importance of public access to scientific data and highlight the role of new media in engaging the public with space research. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40389]

Screenwriter and playwright Phyllis Nagy joins moderator Patrice Petro for a discussion of Alfred Hitchcock's 1951 classic Strangers on a Train. Adapted from Patricia Highsmith's debut novel, the film follows tennis player Guy Haines (Farley Granger), who meets the charming but disturbed Bruno Anthony (Robert Walker) during a chance encounter on a train. Bruno proposes they “swap” murders—he'll kill Guy's wife, and Guy will kill Bruno's father—eliminating any obvious motive. When Bruno follows through, Guy finds himself caught in a dangerous game of blackmail and suspense. Known for its striking visual style and psychological complexity, Strangers on a Train is celebrated as one of Hitchcock's most influential thrillers, offering a masterclass in tension and moral ambiguity. Series: "Carsey-Wolf Center" [Humanities] [Show ID: 40542]

Scientists, leaders, and patients discuss the intersection of cutting-edge science and real-world impact. They explore the importance of patient perspectives in shaping medical advancements and how collaboration fuels groundbreaking research. Key scientific achievements in areas like regenerative medicine, cancer therapies, and space biology are highlighted. The group emphasizes the need for scientists to engage more with the public—through social media and media appearances—to help people understand and value the life-changing discoveries in science. Featuring: Catriona Jamieson, M.D., Ph.D. UC San Diego Sandra Dillon Patient Advocate Alexander Khalessi, M.D., M.B.A. UC San Diego Jana Stoudemire Celestial Strategy, LLC Alysson Muotri, Ph.D. UC San Diego Rebecca Moores Philanthropist and Patient Advocate Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40519]

A Parent's Guide to San Diego Schools is a valuable, research-driven resource that helps families navigate school choices with confidence. This year, the guide takes a deeper look at the powerful role Career Technical Education (CTE) plays in shaping student success beyond the classroom. In a discussion led by Morgan Appel of UC San Diego, Andrea Lopez-Villafaña and Jakob McWhinney of Voice of San Diego highlight how CTE programs provide early, hands-on learning that builds practical skills, boosts confidence, and creates direct pathways to meaningful careers. Taylor Dunne of the San Diego Regional Economic Development Corporation adds that when CTE offerings are matched with up-to-date labor market data, students are not just learning—they're preparing for real opportunities in San Diego's evolving job market. The panel agrees that while the guide offers important data and comparisons, there's no substitute for visiting schools and seeing where students truly thrive. Series: "Career Channel" [Business] [Education] [Show ID: 40597]

In our latest Earth Serenade, we bring you a meditative flight over the Sahara and an exploratory path over the Atlantic Ocean and Europe as we further explore Bach's Art of the Fugue. MDR Sinfonieorchester of Leipzig, Germany, brings us these two movements to accompany the visuals taken by ISS astronauts on Expeditions 67 and 69. Series: "Earth Serenade" [Arts and Music] [Show ID: 40754]

Nicholas Baer, author of Historical Turns: Weimar Cinema and the Crisis of Historicism, joins moderator and Carsey-Wolf Center Director Patrice Petro for a discussion of Sunrise: A Song of Two Humans. Series: "Carsey-Wolf Center" [Humanities] [Show ID: 40537]

As part of the 2025 Developmental Disabilities Conference, Amged Soliman from the National Council on Disability provides an update on health disparities. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 40603]