University of California Audio Podcasts (Audio)

In this excerpt, Dr. Natalie Marshall responds to a question about taking nutritional supplements. Dr. Marshall speaks on the importance of getting vitamins through natural foods. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 41185]

Public health often works behind the scenes—preventing illness, protecting communities, and generating research that too often stays hidden behind paywalls. In a world of eroding trust and rising falsehoods, Dr. Katelyn Jetelina, an epidemiologist and scientific communicator, explores how we can make the value of public health visible: by telling better stories with data, making science more accessible, and ensuring communities see themselves in the work before, during, and after crisis. Series: "UC Berkeley Graduate Lectures" [Health and Medicine] [Show ID: 41066]

Intermittent fasting isn't just about calories—it's about timing. Michael J. Wilkinson, M.D., F.A.C.C., F.N.L.A., explains how time-restricted eating aligns daily food intake with the body's natural circadian rhythms. He shares insights from animal studies, clinical trials, and UC San Diego research showing how consolidating meals into an 8–10 hour window can improve glucose control, blood pressure, and metabolic health. Wilkinson highlights why earlier eating windows may work best, what makes studies succeed or fail, and how these findings point to practical strategies for preventing cardiometabolic disease and supporting healthy aging. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41184]

A collaborative effort examines how organizations confront religious intolerance, focusing on antisemitism and Islamophobia. It maps an ecosystem of practices across individual, community, and structural levels. Using surveys, interviews, and existing research, the project documents what people and organizations do and why. Approaches include education and skills training; supports for healing and wellbeing; bridging divisions, leadership, coalitions, safer online spaces, and civic engagement; work on policy and law; research and evaluation that advance evidence-based programs; and storytelling that promotes inclusion while challenging hateful speech. Together, these efforts clarify how combined work builds belonging, trust, understanding, and accountability. Findings are shared to help communities adapt effective practices locally, including on campus and across the region. The goal is to support practical, adaptable strategies that cultivate safer, more inclusive environments. [Public Affairs] [Show ID: 40703]

Biological resilience underpins healthy aging, and Anthony Molina, Ph.D., investigates how people resist, adapt to, and recover from age-related stressors. Molina defines three domains of resilience linked to aging and studies “life course” resilience using the Rancho Bernardo Study, a longitudinal cohort that starts in 1972 and tracks cognitive, sensory, physical function and comorbidities. His group analyzes trajectory scores from tasks such as the trail-making test and examines thousands of blood molecules to identify patterns that distinguish exceptionally resilient participants. Laboratory experiments show how age-related molecular profiles relate to mitochondrial function and ATP production. Molina's team also tests behavioral and nutritional interventions in rigorously designed clinical studies, combining molecular biomarkers of biological age with measures of physical performance, cognition, sensory abilities, and mental well-being. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40958]

David Gokhman of the Weizmann Institute of Science explores how changes in gene regulation shaped recent human evolution. His team used massively parallel reporter assays in skeletal and neural cells to test 71,443 genetic variants that distinguish Neanderthals and Denisovans from modern humans, building a catalog that reveals hundreds of noncoding variants that alter gene expression. The work uncovers evolutionary trends and examples of convergent evolution, including an enhancer of KDM8, a gene involved in tumor progression, that was completely silenced in both archaic and modern human lineages through different mechanisms: motif disruption in Neanderthals and Denisovans, and hypermethylation in modern humans. Gokhman also introduces a way to reconstruct anatomical profiles from DNA sequence and methylation, using it to model Denisovan anatomy and scan the fossil record. The results suggest that the Harbin and Dali fossils were likely Denisovans, while Kabwe may have been related to the ancestor of Neanderthals and Denisovans, helping to clarify the regulatory changes underlying human evolution. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41195]

Peter Godfrey-Smith, Professor of History and Philosophy of Science at the University of Sydney, explores the evolutionary roots of consciousness by surveying animal evolution and the emergence of felt experience in several lineages. He examines two central philosophical questions: how such experience might arise gradually, existing in partial forms, and whether it represents a single unified feature with variations or instead a cluster of distinct traits. Author of "Darwinian Populations and Natural Selection," and "Living on Earth: Forests, Corals, Consciousness and the Making of the World," Godfrey-Smith brings his expertise in philosophy of biology and mind to illuminate how consciousness may have emerged and why its origins remain a profound puzzle. Series: "UC Berkeley Graduate Lectures" [Humanities] [Science] [Show ID: 41065]

The sequencing of genomes from archaic humans, such as Neanderthals and Denisovans, has transformed our understanding of human evolutionary history. These ancient genomes reveal that modern humans did not evolve in isolation but interbred with now-extinct groups, leaving lasting genetic legacies. To date, genomic sequences from 31 archaic human individuals, including four sequenced to high coverage, have provided unprecedented insights into the population structure, social organization, and adaptation of this now-extinct lineages, allowing us to reconstruct our own evolutionary history and the mechanisms that led to modern human success. Diyendo Massilani of Yale University School of Medicine reviews nearly three decades of research on archaic human DNA and what we have learned about how these groups lived, as well as how admixture between different lineages may have contributed both to the extinction of archaic humans and the thriving of modern humans. Ultimately, ancient genomes show that the success of our species was not predetermined but forged through encounters, exchanges, and adaptations, and that the legacies of archaic humans live on in our biology today, continuing to influence what it means to be human. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41193]

Alejandro Sánchez Alvarado, Ph.D., argues that real progress in understanding regeneration comes from studying whole organisms rather than cells grown under artificial conditions. Sánchez Alvarado shows how observations from intact animals reveal organizing rules that narrow laboratory systems can miss. He presents evidence that stem cells in a studied animal lack detectable junctions with neighboring cells and instead respond to signals that travel across tissues. Sánchez Alvarado links this communication to extracellular vesicles that carry RNA and to metabolic support involving creatine, highlighting how distant tissues influence repair. Using imaging and molecular analyses, he tracks how signals move through the body and how specific cell populations change state during recovery. Sánchez Alvarado concludes that broad, comparative research is essential for uncovering general principles that govern how adult tissues restore form and function. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40454]

Climate investor and philanthropist Tom Steyer, recipient of the 2025 Charles David Keeling Memorial Lecture, talks about the current and future state of energy. In a conversation with Scott Lewis of Voice of San Diego, Steyer argues that capitalism and policy must work together at scale, and highlights the marketplace rise of renewables like solar and EVs alongside challenges like slow fossil-plant retirement, grid constraints, and the need for longer-duration storage. He also discusses emerging options such as advanced geothermal and nuclear. The Keeling Memorial Lecure is given by a prominent member of the global change community able to speak on topics that reflect the legacy of Keeling's work. [Science] [Business] [Show ID: 41034]

Cris Liang, a UC San Diego alumnus trained in engineering, explains how a cross-border upbringing and family entrepreneurship guided his move from engineering to hospitality. He grew up between Mexico and the United States, spoke Cantonese and Spanish at home and in the community, and came to see food as a bridge that connects cultures and neighborhoods. His restaurants focus on community, offering welcoming places to share meals and friendships. Liang emphasizes relationships, resilience, and long-term purpose over quick wins. In this interview with Frank Silva, his practical creativity comes through as he reflects on identity, perseverance, and the power of hospitality to bring people together. Series: "Education Channel" [Business] [Education] [Show ID: 40974]

Michael J. Wilkinson, M.D., F.A.C.C., F.N.L.A., explains how aligning when we eat, sleep, and move with our body's natural circadian rhythms can profoundly affect metabolic health. Drawing on research from UC San Diego and the Salk Institute, he explores how disruptions in daily patterns—late-night eating, less movement, artificial light—contribute to obesity, diabetes, and fatty liver disease. Wilkinson shows why *when* we eat may be as important as *what* or *how much* we eat, and how time-restricted eating offers a practical, biology-based strategy for preventing cardiometabolic disease and promoting healthy aging. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41187]

In this excerpt, Dr. Natalie Marshall focuses on high intensity interval training, or HIIT. Dr. Marshall discusses the health benefits of HIIT which can be achieved in a short amount of time. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 41186]

The genome sequences of Neandertals and Denisovans have provided a wealth of new information about the origins, migrations, and interactions of ancient humans. These genomes have revealed that mixture between hominin groups was common: all modern humans outside Africa carry around 2% Neandertal DNA from a single major episode of Neandertal gene flow, while the ancestors of present-day Asians and Oceanians also met and mixed with multiple, genetically distinct Denisovan populations. Archaeological evidence suggests multiple dispersals of modern humans out of Africa, with early fossils identified in East and Southeast Asia over 50 thousand years ago. In contrast, genomic studies indicate that all present-day non-African populations descend primarily from a single dispersal after ~50 ka, though the migration routes of ancestral populations across Eurasia and Oceania remain unclear. Janet Kelso, professor at Max Planck Institute for Evolutionary Anthropology, shows how using the distribution of Neandertal and Denisovan ancestry in ancient and present-day modern humans can determine when, where and how often modern and archaic humans met and mixed. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41192]

A documentary film celebrating the work, wit and wisdom of internationally acclaimed glass paperweight artist Paul J. Stankard. [Arts and Music] [Show ID: 41122]

An in vivo brain organoid platform reveals how human neurons and glia interact across development, aging, and disease. Fred H. Gage, Ph.D., generates three dimensional organoids from induced pluripotent stem cells and examines their maturation, synapses, and network activity with two-photon imaging and single-cell profiling. Gage integrates human microglia and astrocytes to study immune signaling, injury responses, and support functions that shape circuit behavior. Transplantation enables vascularization, reduces cell death, and yields features consistent with a blood brain barrier. Analyses identify diverse astrocyte types and trajectories, while patterns of tau expression inform Alzheimer's disease modeling. Gage also converts adult fibroblasts into age retaining neurons that assemble into 3D spheroids, creating complementary models to connect genes, cells, and circuits with pathology and to guide strategies for prevention and therapy. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 41160]

It is well known that inside nearly every living cell on this planet, there are instructions powering the dynamics of everything in the cell, known as deoxyribonucleic acid (DNA). Enoch Yeung, Associate Professor of Mechanical Engineering at UC, Santa Barbara, explains how DNA is the genetic code that tells cells where to live, how to live, and how to adapt when things get tough. Editing DNA has unlocked new potential in biology, enabled new therapeutics, diagnostics, and modes of treating diseases. Since DNA is double-stranded, it literally maintains a backup copy of itself to proof-read and facilitate stability of code. The double-stranded nature of DNA also means it can sometimes encode two messages in a given length! In short, DNA is amazing. Series: "GRIT Talks" [Science] [Show ID: 41040]

Michael J. Wilkinson, M.D., F.A.C.C., F.N.L.A., responds to the question, "How long does it take to get used to Intermittent Fasting?" Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41183]

If you feel like there's more rudeness in the world, you're not alone. According to John O'Brien, psychologist and author of "Rudeness Rehab," there's a pandemic of incivility. O'Brien says we're seeing bad behavior everywhere, from the streets to the workplace to even the operating room. As part of our Osher Author Talk series, host Henry DeVries talks with O'Brien about the physical and mental toll of experiencing rudeness. O'Brien says we have the power to be our own superhero when dealing rude and difficult people. He calls his approach BAM, which stands for breathing, active listening and mindfulness. Series: "Osher UC San Diego Distinguished Lecture Series" [Health and Medicine] [Humanities] [Show ID: 40599]

Clinical trials turn scientific discoveries into real options for patients and volunteers, advancing care while safeguarding participants. Sheldon Morris, M.D., M.P.H., explains how independent oversight, core ethical principles, and stepwise phases evaluate safety and benefit, and clarifies participants' rights and responsibilities. Sandip Patel, M.D., F.A.S.C.O., highlights how carefully designed studies open access to promising cell and gene-based approaches while balancing risks and benefits. Robert A.J. Signer, Ph.D., underscores why participation—including consenting to share samples and data—helps researchers understand disease and accelerate better treatments. Morris, Patel, and Signer point audiences to practical ways to locate studies through registries and national databases, discuss what costs are typically covered, and advise asking questions about study design and safety. They also caution against unproven “stem cell tourism” and emphasize informed decisions. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40438]

Nature has been running chemistry experiments for over 4 billion years—yet today, much of modern organic chemistry still depends on wasteful, resource-heavy methods that rely on oil-based solvents. These solvents aren't recycled, and when burned, they release CO2, adding to climate change. But what if chemistry could be done differently? Bruce Lipshutz, Distinguished Professor of Chemistry at UC Santa Barbara, shows how it's possible to carry out organic reactions in water—nature's own solvent. His research demonstrates that chemistry in water isn't just more sustainable, it can also be faster, cheaper, and more effective than traditional approaches. Series: "GRIT Talks" [Science] [Show ID: 41029]

Writer R.F. Kuang has quickly become one of today's most daring and original voices in fiction, blending sharp social critique with rich storytelling. Her most recent novel, Katabasis, takes readers on a darkly witty descent into the underworld, where academia, ambition, and myth collide. Known for tackling power, politics, and the human cost of ambition, Kuang first captivated audiences with The Poppy War and later with the wildly successful Babel, both of which showcased her ability to fuse historical depth with page-turning drama. As part of the 30th anniversary of the Writer's Symposium by the Sea, Kuang joins host Dean Nelson for a delightful conversation at Point Loma Nazarene University. Series: "Writer's Symposium By The Sea" [Humanities] [Show ID: 40781]

Circadian timing shapes how we sleep, feel, and function each day. Satchidananda Panda, Ph.D., Salk Institute, explains that keeping daily light, meals, movement, and sleep in step with the body's internal clock supports alertness, metabolism, and recovery. Panda notes that evening light and late eating can make it harder to fall asleep and may work against healthy glucose control, while thoughtful timing of activity can improve energy and rest. He highlights that when we take medicines matters because the body's response changes across the day. Travel and shift work challenge these rhythms, but simple habits with light exposure, meal timing, and sleep can ease the strain. Panda also describes ongoing efforts testing practical routines, including limited daily eating windows paired with light and activity strategies. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40733]

Focused ultrasound (FUS), also called high-intensity focused ultrasound (HIFU), is a noninvasive treatment using sound waves to address essential tremor and tremor-dominant Parkinson's disease. Drs. Doris Wang and Leo Sugrue of UCSF explain how FUS and deep brain stimulation work to reduce tremor, outline which patients may benefit, and describe how the UCSF team individualizes treatment. Series: "UC San Francisco News" [Health and Medicine] [Show ID: 41035]

We're surrounded by digital devices—from phones and tablets to streaming platforms and social media. With so many options at our fingertips, each of us faces choices about when and how to use technology in ways that align with our goals and values. In this talk, Kristy Hamilton, Assistant Professor in the Department of Communication at UCSB, shares research on how digital media shapes the way we see ourselves and, in turn, influences our everyday technology use. Hamilton uses experimental methods to study the strengths and challenges of human memory and cognition in digital environments, with the aim of helping people become more effective thinkers in today's media landscape. Series: "GRIT Talks" [Science] [Show ID: 41030]

Language and the law is a field growing in size and importance. While some forensic linguistics applications -- e.g. authorship attribution -- have a wider tradition, this growth is particularly acute in the domain of legal interpretation, which is increasingly using corpus data and methods. Stefan Gries, Professor of Linguistics at UC Santa Barbara, discusses two recent applications. One is from recent work as an expert witness for a law firm; it is a more quantitative application and concerned with authorship attribution in an internet trolling case. The other is concerned with more quantitative and qualitative research for an amicus brief to the Supreme Court. Series: "GRIT Talks" [Public Affairs] [Show ID: 41041]

Danielle K. Glorioso, LCSW, examines resilience as a skill that can be strengthened. Glorioso explores the many health benefits of resilient behavior. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41123]

Campus-based mental health response matters everywhere, providing timely help that prevents crises and keeps students thriving. At UC San Diego, Triton CORE's mobile, trauma-informed clinicians meet students where they feel safest and connect them to least restrictive care. Series: "Education Channel" [Health and Medicine] [Education] [Show ID: 40955]

Founded in 1975, UCSF Fresno commemorates 50 remarkable years of training local doctors and improving healthcare in California's Central Valley in 2025. UCSF Fresno is a regional campus of UCSF's School of Medicine, located in the heart of California's San Joaquin Valley. By both serving and drawing strength from extraordinarily deep community roots, UCSF Fresno brings critical health care to families while to growing the next generation of health care providers and researchers. [Health and Medicine] [Show ID: 40987]

Batteries have become an essential component of our daily life. They power our smartphones, laptops, tablets, and many of the cars around us. They are also key to the renewable energy transition. Building better batteries requires the design of materials whose chemical composition and structure evolve drastically on charge and discharge, yet those changes must be perfectly reversible for the device to sustain hundreds or thousands of charge-discharge cycles. Raphaële Clément, Associate Professor of Materials Department at UC Santa Barbara, explains why this is a challenging task that necessitates an atomic-level understanding of the inner workings of battery materials. Clément is working to establish materials design rules and optimize materials processing approaches to advance electrochemical energy storage. Series: "GRIT Talks" [Science] [Show ID: 41031]

Urinary incontinence and sexual dysfunction are common side effects of prostate cancer treatment, but both are manageable. Dr. Lindsay Hampson explains the types of incontinence—stress, urge, mixed, and overflow—and how identifying the cause guides treatment. Management strategies include pelvic floor physical therapy, medications, and surgical options like slings or artificial urinary sphincters. For sexual dysfunction, approaches range from oral medications and vacuum devices to injections and implants. Dr. Michael Rabow also highlights the side effects of androgen deprivation therapy, including fatigue, depression, hot flashes, and cardiovascular risk. He outlines evidence-based strategies—like exercise, cognitive behavioral therapy, and medications—to help preserve well-being and quality of life during treatment. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 40869]

Peter Bolland, professor of philosophy and humanities at Southwestern College, explores the lasting influence of Augustine of Hippo. Born in North Africa in 354, Augustine—now known as Saint Augustine—is remembered as one of Christianity's most important thinkers. He shaped core beliefs like the doctrine of original sin and wrote The City of God, a work meant to comfort Christians after Rome fell to the Visigoths in 410. His words offered guidance in a moment of chaos and uncertainty. Closer to home, Augustine dedicated his life to persuading the people of Hippo to embrace Christianity, tirelessly working to share his vision of faith, community, and resilience. Series: "Osher UC San Diego Distinguished Lecture Series" [Humanities] [Show ID: 41056]

Psychological resilience in later life examines how older adults adapt after adversity and cultivate everyday practices that sustain well-being and purpose.Elizabeth W. Twamley, Ph.D., introduces and guides a discussion on mental health and resilience among older adults. Ellen E. Lee, M.D., characterizes resilience as dynamic learning oriented toward flourishing and urges a low threshold for seeking help when symptoms overwhelm daily routines. Sidney Zisook, M.D., presents grief as adaptation to loss, distinguishes acute from integrated grief, and explains how intense waves of emotion gradually become less frequent and more manageable; he views psychedelic therapies as promising but not ready for routine treatment. Marti E. Kranzberg shares practical approaches that include mindfulness, journaling, gratitude, movement, sleep, pain management, creative arts, time in nature, community, and purpose. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40963]

Danielle K. Glorioso, LCSW, explores the complex nature of grief, emphasizing that it is a lifelong, evolving response to loss rather than something to “get over.” She explains the differences between acute grief, integrated grief, and prolonged grief disorder. Drawing on both professional expertise and personal loss, Glorioso offers practical strategies for coping, supporting others, and finding hope while honoring the memory of loved ones. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41121]

Artist and filmmaker Tom Kalin joins moderator Bhaskar Sarkar (Film and Media Studies, UCSB) for a discussion of his 1992 film Swoon. Kalin discusses the historical background of the film (the famous 1924 Leopold and Loeb murder case), how he reimagined the case through the lens of queer desire, and how he conducted archival research into the central figures of the murder. Kalin also discusses how his background and training as a visual artist fed into his work in feature-length film making. Series: "Carsey-Wolf Center" [Humanities] [Show ID: 40927]

Cognitive resilience grows from small, consistent habits that keep the brain adaptable. Fadel Zeidan, Ph.D., frames mindfulness as mental training that improves attention, processing, and the way people relate to pain. Erin E. Sundermann, Ph.D., underscores modifiable pathways to healthier aging, highlighting movement, social connection, hearing support, and lifelong learning as mutually reinforcing drivers of brain health. Raenne C. Moore, Ph.D., centers practical strategies that translate into daily life, including routines, planned breaks, reducing distractions, and attending to anxiety or depression. Carolyn Dunmore, an older adult community Mmmber, exemplifies resilience through steady activity, purposeful community roles, faith, self-compassion, and the “use it or lose it” mindset. Together, Zeidan, Sundermann, Moore, and Dunmore point to a clear theme: everyday practices accumulate to support memory, attention, and well-being as people age. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40962]

Marisa Korody, Ph.D., leads groundbreaking work at the San Diego Zoo Wildlife Alliance's Beckman Center for Conservation Research, where scientists use advanced genetic and stem cell technologies to protect endangered species. Korody highlights efforts to save the critically endangered northern white rhino by developing induced pluripotent stem cells that can be transformed into egg and sperm precursors, offering a potential path to revive the species. This research is part of a broader conservation mission that includes global projects in genetics, reintroduction, and community engagement. By combining cutting-edge science with wildlife management, the San Diego Zoo Wildlife Alliance works to preserve biodiversity and ensure the survival of species threatened by habitat loss, poaching, and climate change, demonstrating the critical role of innovation in conservation. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40451]

Targeting the biology of aging offers a path to stronger resilience and longer health. John C. Newman, M.D., Ph.D., explains that aging arises from measurable cellular processes, often called hallmarks of aging, including changes involving mitochondria, stem cells, cellular senescence, inflammation, and protein quality control. Newman describes how basic science in model organisms reveals mechanisms that can be manipulated to extend healthy lifespan and guide therapies. Emerging approaches aim either to strengthen stress responses that make cells more resilient or to address downstream consequences. Many clinical studies across the country now test interventions that target aging, supported by national efforts to standardize methods and expand training. Newman also investigates ketone bodies as energy sources that influence inflammation, muscle preservation, and other processes relevant to frailty and recovery. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40961]

Advances in precision medicine and patient advocacy are transforming the way cancer is understood and treated. Nikoo McGoldrick shares her personal journey with metastatic breast cancer, emphasizing the importance of patients having a voice in their care. Sheldon Morris, M.D., M.P.H., explains how regenerative medicine progresses through stem cell therapies, gene therapies, CAR-T cell treatments, and small molecules, with clinical trials addressing cancer, autoimmune disorders, and neurological diseases. Sandip Patel, M.D., F.A.S.C.O., highlights cancer stem cells as key drivers of relapse and resistance, describing precision medicine approaches, novel CAR-T therapies, and the role of artificial intelligence in cancer detection and treatment. Rebecca Shatsky, M.D., focuses on breast cancer as a systemic disease linked to dormant cancer stem cells, underscoring the need for genomic and immune-based therapies, including innovative antibody treatments and targeted clinical trials. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40910]

Film producer Liz Yale Marsh and mustang wrangler West Taylor join moderator and co-producer Wendy Eley Jackson to discuss their work on the documentary Facing the Falls, which follows disability rights advocate Cara Elizabeth Yar Khan and her twelve-day expedition through the Grand Canyon. They explore how Yar Khan's muscle disease provided a unique challenge to navigating the Grand Canyon, as well as how Marsh and Jackson came onto the film in post-production and helped to finish the project. Series: "Carsey-Wolf Center" [Humanities] [Show ID: 40926]

Healthy aging starts with physical resilience, the body's ability to withstand and recover from stress. Maile Young Karris, M.D., defines the concept and sets the stage for practical strategies that match real-world needs. Ryan J. Moran, M.D., M.P.H., recommends simple routines such as wall push ups, posture alignment, and chin tucks, and he links posture and vision to fall prevention; social connection helps people stick with movement. Theodore Chan, M.D., F.A.C.E.P., F.A.A.E.M., explains that age alone is a poor predictor of outcomes in acute care and that functional resilience strongly influences decisions. Gail Levine emphasizes accountability, community, and balanced nutrition. Moran highlights protein needs of about 1 to 1.2 grams per kilogram plus calcium with possible vitamin D, and he favors plant focused eating with limited processed foods. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40960]

Dr. Rahul Aggarwal presents emerging treatments for advanced prostate cancer, highlighting rapid advances in drug development. He outlines therapies targeting cancer cell surface proteins beyond PSMA, including CD46, B7-H3, and DLL3, and explains how antibody-drug conjugates deliver potent chemotherapy directly to tumors. He also discusses bispecific T-cell engagers designed to trigger immune attacks on cancer cells, including promising results from agents like Talquetamab. Aggarwal explores new isotopes such as actinium-225 for radioligand therapy, which may offer stronger and more durable responses than current treatments. He emphasizes continued innovation in targeting the androgen receptor, with drugs that degrade the receptor or block androgen production more effectively than existing therapies. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 40813]