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In this episode of Longevity by Design, host Dr. Gil Blander sits down with Dr. Emeran Mayer, Executive Director at the UCLA Center for Neurobiology of Stress and Resilience and founder of Mayer Interconnected. They explore the science behind the gut-brain connection and its role in shaping health and longevity.Emeran explains how signals flow between the brain, gut, and microbiome, influencing everything from digestion to emotions. He breaks down how modern diets, especially ultra-processed foods, disrupt the natural balance between humans and gut microbes—a relationship refined over thousands of years. The conversation highlights why early life exposure to antibiotics can have lasting effects on microbiome resilience, and how lifestyle choices like diet and exercise remain powerful tools for supporting gut-brain health at any age.The discussion closes with a look toward the future of gut-brain science, including engineered probiotics and the promise of more targeted therapies. Emeran shares practical habits for better gut-brain health and cautions against quick-fix “biohacking,” encouraging a return to whole foods, movement, and mindful living.Guest-at-a-Glance
Welcome back to our weekend Cabral HouseCall shows! This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track! Check out today's questions: Amy: Hi Dr. Cabral. I appreciate everything that you do for the community! My question is about heart palpitations for someone in perimenopause. I notice them only slightly during the day but it seems they really ramp up in the evening. In addition, my energy plummets and I feel incredibly tired and foggy headed. I've had my hormone levels checked and everything seems fine, so I'm wondering if you have any thoughts on what I should check next. My gut tells me maybe I should look into cortisol, but I also know it could be one or multiple other factors. I appreciate your thoughts. Whitney: Curious about your perspective on various medspa type aesthetic treatments like collagen tightening (usually via radio frequency/ heating deeper layers of tissue), lasers for skin dark spots or resurfacing, PRP micro needling, or at home micro needling? Wondering if these will have other damaging side effects etc? Thanks !! Whitney: What are your thoughts on tattoo removal ? I was thinking about getting some tattoos removed but wasn't sure if I could detox my way out of all the harmful side effects since I guess my body would have to do something with that ink that is removed ? Or is it just as harmful as is it now in my skin ? Thanks ! Jodi: Hello, I am scheduled to have an MRI with a gadolinium based contrast this Friday. The reason for it is two-fold. 1) They want to look at my pancreas. My recent blood work shows I have very high Lipase at 232 U/L and High Amylase at 118 U/L. I don't have any symptoms indicating pancreas issues. My Lipase was also high in blood work 6 months previously and has continued to climb. 2) Follow up scan for polycystic liver disease (well over 100 cysts on my liver) as well as a solid lesion on my liver which was believed to be benign when it was discovered about 7 years ago. Now I am beginning to panic as I have read that the metal from the dye cannot fully be detoxed. Is there another option for the dye? have more to say but not enough characters in this email. Rebecca: Hi Dr Cabral I had an allergic reaction to an antibiotic that caused me to loose consciousness probably at least 30 times or more and in between losing consciousness I would yell in pain because my whole body went into spasms. My brain was starving for oxygen so it started taking the oxygen from the muscles because my body started shutting down. I have had brain fog really bad since it happened 2 months ago. Is there anything I can do about the brain fog? Thank you Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions! - - - Show Notes and Resources: StephenCabral.com/3585 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!
Join Dr. Pinkston and special guest Dr. Lesser from Magna Pharmaceuticals as they discuss the connection between the immune system, the common cold, and allergies (Upper Respiratory Symptoms, or URIs). In this highly relevant episode, Dr. Lesser delves into: Myths and Facts surrounding the common cold, including debunking old wives' tales. The Four Stages of the common cold, from incubation to recovery. The profound ways that colds and allergies can impair cognitive function, sleep, mood, and relationships. The critical role of a strong immune system and the importance of being proactive with prevention and treatment. Preventative measures like hygiene, exercise (myokines), and the impact of sleep on immune restoration. Identifying the difference between cold and allergy symptoms, including the significance of mucus color. Appropriate treatments for symptoms, emphasizing when to use decongestants, mucolytics, and when antibiotics are not the answer. Tune in to learn how an integrative approach, combining holistic health and contemporary medical information, can help you and your family navigate the cold and allergy season for a better life!See omnystudio.com/listener for privacy information.
Earlier this month I saw several news stories about new antibiotics, some even developed with AI. Miracle medical breakthrough, or not? Why not ask infectious diseases physician and overall medtech nerd Dr Trent Yarwood.In this episode Trent and I talk about antimicrobial resistance, the new antibiotics including premethylenomycin C lactone, nafithromycin, and a couple developed using AI, a potential cure for HIV, the problem with relying on electronic health records, and the word “moist”.Full podcast details and credits at:https://the9pmedict.com/edict/00257/Please consider supporting the podcast by pledging to our seasonal crowdfunding campaign by 10 December 2025.https://the9pmedict.com/summer2025If you miss that deadline then please go toLhttps://the9pmedict.com/tip/https://skank.com.au/subscribe/
Listen in as experts Thomas P. Lodise, PharmD, PhD, and George Sakoulas, MD, FIDSA, explore tailored antibiotic strategies for diverse patients with acute bacterial skin and skin structure infections (ABSSSIs). Their insightful discussion focuses on antibiotic developments that followed publication of the IDSA practice guidelines in 2014 and the challenges unique to ABSSSIs, including a lack of determined bacterial etiology for many cases. PresentersThomas P. Lodise, PharmD, PhDProfessorAlbany College of Pharmacy and Health SciencesInfectious Diseases Clinical Pharmacy SpecialistStratton VA Medical CenterAlbany, New YorkGeorge Sakoulas, MD, FIDSAChief, Infectious DiseasesSharp Rees-Stealy Medical GroupAdjunct Professor of PediatricsUniversity of California San Diego School of MedicineSan Diego, CaliforniaLink to full program:https://bit.ly/4oIKwzsGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Andy’s Brave New World: Part 1 Ranger Andy survives, the apocalypse in Yosemite. Based on a post by the hospital. Listen to the Podcast at Explicit Novels. Day 1, Yosemite National Park The park was busy with spring visitors when the first reports came in. Tourists coughing in the visitor center, a family requesting medical assistance at Upper Pines campground. Andy helped coordinate with the park's small medical team, radioing updates to other rangers. Standard protocol for illness in the park, nothing too concerning yet. That evening, things took a turn, with the news reporting an alarming spread of similar outbreaks across California, and the world. Possibly a new avian flu, they said. Day 2 Everything accelerated. Half the ranger staff called in sick. The small park clinic was overwhelmed. Andy helped organize an evacuation point at the visitor center, trying to get sick tourists to hospitals in Fresno or Modesto. His training kicked in, calm, professional, reassuring visitors even as his colleague Declan started coughing blood next to him. The ill began dying in droves. The park superintendent ordered all non-essential personnel to evacuate. Andy stayed, helping the remaining medical staff set up an impromptu care center in the lodge. By the evening, Andy felt a fever rise and was soon sweating through his clothes and coughing up a lung. He weakly barricaded himself in his cabin and prepared to die like the others. Day 3 The next morning, Andy woke to fine himself still alive, surprised to feel slightly better than the night before. He pulled himself out of his cabin and began his duties. The radio channels went quiet one by one. No response from Fresno hospitals. The lodge had become a morgue. He spent the morning doing rounds, checking campsites, finding mostly bodies or critically ill visitors who died within hours. By evening, he was the only ranger still moving around. He did his best to care for the sick and dying. Andy wasn't entirely sure if this was all just an awful dream. Day 4, Morning The cough remained in his chest that morning, but Andy forced himself to continue his rounds. The ranger truck's tires crunched over broken glass in the parking lot as he checked North Pines Campground. Most sites were abandoned, their occupants having fled days ago. Others contained what he couldn't let himself think about yet. His fevered brain kept switching between ranger protocol and survival instinct. Check each site. Document. Radio in-- no, the radio was silent now. Just static and occasional distant screams that were becoming less frequent. That's when he saw it, an expensive ultralight tent in millennial pink and gray, surrounded by matching gear that looked straight out of an R E I catalog. Too pristine, barely used. A small solar charger lay futilely pointed at the clouded sky. "Hello?" His voice was rough from coughing. "Ranger service. Anyone alive in there?" "Define 'alive,'" came a strained but steady voice, followed by a cough. Andy approached cautiously, unsnapping his holster out of habit though he knew he wouldn't need it. Inside, a young woman sat cross-legged in the tent entrance, her expensive Lululemon sports bra and high-waisted hiking shorts soaked through with fever sweat. Despite everything, the death, the horror, his own fever, Andy couldn't help noticing how the wet fabric clung to her curves. Her figure was exactly the type that dominated outdoor Instagram, slim waist, toned stomach, curved hips, the sports bra struggling to contain what was clearly meant to be shown off just enough to stay within platform guidelines. He tried to push the thoughts away and focus, but his eyes kept betraying him. She looked up at him with clear eyes, fever-bright but alert. Mixed Asian-white features that hit that perfect social media sweet spot, even through the fever, high cheekbones, full lips, almond-shaped hazel eyes. Her carefully highlighted hair was plastered to her neck, mascara smudged but intact, like she'd been maintaining her appearance out of sheer habit until the fever hit. A few light freckles stood out against her flushed skin. "I'm guessing the 'shelter in place' order isn't working out great for everyone else either?" "I'm Ranger Rhee. Andy," he said, noting how her hands trembled slightly as she reached for her water bottle. "You're sick, but; not like the others." "Sarah Chen-Mitchell," she managed between sips. "And yeah, I noticed. Been listening to people cough and die all night while I just sat here with what feels like a really bad flu. Not exactly the wilderness experience I was going for." Her attempt at humor was undercut by the raw edge in her voice. Andy saw her Instagram-ready camp setup, the coordinated cookware still in its packaging, the expensive camera carefully wrapped in a rain cover, the rose gold water bottle. "We need to get you somewhere safer. Can you walk?" "Yeah, just;" She stood unsteadily, unconsciously adjusting her sports bra, a reflexive gesture that seemed absurd given the circumstances. "My car's blocked in. I tried to leave but;" She gestured at the chaos of abandoned vehicles hemming in her pristine Subaru, many with now-deceased occupants. "Look, I've got medicine and supplies back at my ranger unit," Andy said. "Pack whatever clothes and valuables you need. Leave the camping gear, we can always come back for it if;" he trailed off, not sure how to end that sentence. "Right," Sarah said, still shivering slightly in her wet athletic wear. "I should probably change too." "Do you need help?" Andy asked, then immediately regretted how that might sound. "I mean, with packing. You seem pretty weak." "No, I've got it," Sarah said quickly, pulling herself more upright. "Just; give me a few minutes?" Despite everything, there was still a hint of self-consciousness in her voice. Andy nodded and stepped away from the tent. "Take your time. We're not exactly on a schedule anymore." He heard the tent zip closed, followed by the sounds of her moving around inside. The rustle of fabric as she changed. Multiple bags being opened and closed, more than strictly necessary for just grabbing essentials, he thought. A few quiet muttered comments to herself about what to take. The distinct sound of what had to be a hairbrush being used. Even now, even here, some habits die hard. Or maybe it was just her way of holding onto normalcy for a few more minutes. Andy stood guard, trying not to listen too closely to her movements, scanning the eerily quiet campground. A crow called somewhere nearby. The mountain air was cool and clean, carrying no hint of the devastation it had helped deliver. "Ready," Sarah called softly. The tent zipper opened and she emerged with a large designer backpack, now dressed in a black Alo Yoga tube top that showcased her toned shoulders and pushed up her cleavage, paired with high-waisted leggings that clung to every curve. Her face was scrubbed clean of makeup, but her dark hair was neatly brushed, falling in waves around her shoulders. The fever flush in her cheeks only enhanced her natural beauty, that calculated mix of exotic and approachable that had probably earned her thousands of followers. She caught Andy's gaze traveling over her body and gave a small, knowing shrug, arching her back slightly. "I know, I know. Not exactly survival wear. But it's what I brought for my Instagram hiking content, so;" She did a little pose, definitely more displaying than mocking now, the movement emphasizing her curves. Andy found himself watching much longer than he should, and her slight smile suggested that was exactly the response she'd wanted. "We can probably find you something more practical at the gear store," he managed, forcing his eyes back to her face. "Heavy duty pants, boots, proper rain gear." "Perfect," she smiled, her voice dropping slightly despite her obvious exhaustion. "Though I did bring some actually useful stuff." She knelt by her bag, the movement making Andy struggle to keep his eyes up. "Latest gen military water filter, my dad's company makes them for the marines. Handles way more volume than those little Life Straws. Satellite uplink that'll work even if the normal networks are down. And this;" She pulled out a sleek black device. "GoPro 12 with infrared. Not even on the market yet, I was supposed to demo it next month." Clean water for a larger group. Communications. Night operations. He tried not to sound too eager. "That; could all come in really handy." As they walked to his truck, both carefully kept their eyes forward, ignoring the abandoned cars and what lay inside them. Andy carried her bag despite her token protest, noticing how she stayed close to his side. "So," Sarah said once they were in the truck, adjusting the AC vent toward her flushed face. "How long have you been a ranger here?" The question seemed deliberately normal, almost absurdly so given the circumstances. "Three years here. Before that, two years at Joshua Tree." "Oh, I was just at Joshua Tree! That Hidden Valley trail at sunset, it was so beautiful." She spoke wistfully, her enthusiasm fading as the weight of everything they had experienced in the past three days settled back. Andy gestured at her bag. "Tell me about that gear, you said there was a satellite uplink?" "Right." Sarah dug through her bag, pulling out sleek boxes with military-style lettering. She started reading, her voice growing more confident as she went. "Okay, so this is a 'Starlink Tactical Ground Array', it's got four encrypted receiver units that can talk to each other from anywhere on Earth. Says here it can maintain 4G speeds even without ground infrastructure." She looked up. "Guess Dad's company wasn't just being paranoid with all this survivalist tech." "Wait, you mean that little thing has internet access? I don't see a satellite dish anywhere." "Yeah I think so. I think the array can mimic the behavior of a dish without actually needing one." "That's huge. We really need more information about what's going on." Andy said, feeling hopeful about something for the first time in days. She nodded and moved on to the water system. "This one's cool, processes up to 25 gallons per hour, removes everything down to 0.0001 microns. Works on chemical and biological agents too. If we can get some acid and lye we can keep reusing it forever." "And the camera?" Andy asked. "Let's see; Military-grade infrared imaging, 4K resolution in complete darkness, range up to;" she squinted at the manual. "Thermal detection at 200 meters." "Could probably rig that into a decent night sight," Andy mused, then caught himself. Sarah glanced at his holstered pistol, then out at the empty park road. After a long pause, she cleared her throat and went back to the manual, her voice quieter. "It's got some kind of A I field-of-view system too;" Day 4, Evening After getting Sarah settled at his unit, Andy continued searching for survivors and checking on the dying. Near the clinic, he found Miguel Martinez slumped against a supply cabinet, still in his blood-stained uniform but maintaining his ramrod-straight Marine posture even now. The room around him showed signs of his final efforts, organized medical supplies, careful notes on symptoms, a log of those he'd tried to help. He looked up weakly from his notebook when Andy arrived. "Rhee." Miguel's voice was barely a whisper. "You made it. Figured you might. Always had the look." "Miguel," Andy started, but the older ranger cut him off with a weak wave. "Save it. Listen. Daniela's following protocol at home. She got sick two days ago. But she's stronger. Already sounding better on the radio this morning. She must be immune, like you, alaba al Señor". Immune. Were they immune? The idea hit Andy like a truck. Andy knew Daniela, had helped train her on basic ranger procedures, watched her grow up these past three years. Though only fourteen, her prepper father had subject her to a rigorous marine-style training regimen that made her an extremely competent survivalist. She'd always seemed almost comically over-prepared, showing up to basic first aid training with a full combat medical kit. If there was anyone left to laugh, they wouldn't be now. "Her isolation ends tomorrow morning," Miguel continued. "She knows what to do, but;" Another coughing fit wracked him, blood spattering his arm. "She'll need;" He grabbed Andy's wrist with surprising strength. "You take care of her. After. Promise me." "If it comes to that. I swear." Andy attempted a smile. "Although, she might be the one taking care of me in the end." Miguel chuckled softly. Andy tried to help Miguel up, but the older ranger shook his head. "Too late for me. Already tried everything here. Nothing helps. Just;" He pulled himself straighter. "Just let me finish my notes. Document everything. Might help someone." Andy nodded, throat tight. He gripped Miguel's hand one more time, and they looked each other in the eyes. He gave Miguel a solemn nod, and headed to the Martinez cabin. Through a small clear section in the sealed window, he could see Daniela's silhouette moving around inside, her survival supplies arranged with precision. Just like her father had taught her. "Daniela?" he called softly. She approached the window, and even through the plastic he could see the fever flush in her cheeks. But her voice was strong, clear. "Ranger Rhee. Status report: began showing symptoms approximately 36 hours ago. Fever peaked at 101.2 last night. Currently maintaining isolation." A pause. "Dad mentioned you were coming." "Seems you're also OK, like me. I found another survivor too." Daniela nodded, processing. "Isolation ends at 0600 tomorrow. That's when Dad's supposed to come get me, " Her voice caught. "Is; is dad;? I haven't asked, but; he sounds really weak right now." "We'll see. He's not looking great to be honest, Daniela. I'm sorry." The poor girl tried to maintain composure but Andy could see her eyes well up. She turned away briefly, then turned back. When she spoke again, her voice was wavered slightly. "I'll maintain quarantine until morning." "Are you sure you don't want to go see him? You seem OK, I don't think it would hurt." She shook her head "No. I'll talk to him on the radio. Protocol is protocol." "OK. I'll come get you at six." Andy headed back to his cabin, to Sarah, the weight of Miguel's last watch at the clinic and his daughter's words falling on his shoulders. Tomorrow morning would come too soon, and not soon enough. Day 4, Late Night The commissary had been eerily quiet, its automatic doors frozen half-open. Andy had gathered what he could, protein bars, dried fruit, bottles of water. The walk back to his cabin felt longer than usual, each shadow holding the potential for another body, another victim. He saw the Starlink array before he reached his door, a sleek black apparatus that looked more like a piece of modern art than military hardware. Sarah had positioned the nodes in a complex nested arrangement. Andy was mildly impressed, it looked precisely done. The cabin door creaked slightly as he pushed it open. "Sarah, I got some-" He stopped short. She was curled up in his bed, wrapped in her sleeping bag despite the warmth of the evening. Her face was peaceful in sleep, the fever flush finally fading from her cheeks. Her dark hair spilled across his pillow, and he noticed she'd changed into a pale pink Alo Yoga tank top that looked brand-new. The transformation from her carefully curated daytime appearance was striking. She looked younger, more vulnerable. Andy set the supplies down as quietly as he could and backed out of the cabin. She needed the rest more than she needed food right now. Outside, his phone buzzed, the first notification he'd received in days. The Starlink array hummed softly, its status light steady green. He pulled out his phone with slightly trembling hands and watched as notifications began flooding in. Email. Twitter. News alerts. The world outside the park still existed apparently, somehow. He sat heavily in one of the wooden chairs on his small porch, opened his laptop, and began downloading the prepper manuals Miguel had mentioned so many times, "Emergency Protocols for Systemic Collapse", "Catastrophic Event Recovery, Reference Encyclopedia" and "Technology Bootstrapping, How to Restart Industrial Society". The download started immediately, the normalcy of a digital download almost shocking after days of internet silence. Then he opened Twitter, and his breath caught in his throat. The feed was sparse but active. Scattered voices calling out from around the world, trying to find others. A woman in Seattle reporting that her entire family had survived. A doctor in Mumbai documenting recovery rates. A thread from the CDC, last updated two days ago, describing it as an avian flu with aerosol human-human and human-bird transmission, confirming what Miguel had alluded to, some people got deathly ill, a tiny fraction just got sick and recovered, and there seemed to be no pattern to it. Someone, a software engineer in Morocco, according to the about page, had anticipated the grid's imminent collapse and created a simplified Twitter clone called Beacon. It apparently ran on a solar-powered home server farm with redundant battery backups, designed specifically to operate via Starlink. The site was bare-bones but functional: just a global chronological feed, basic search, hashtags, geotags, and posts limited to 280 characters. One tweet from a virologist caught his eye: "Preliminary data suggests roughly a point 8% survival rate globally. Fascinating gender disparity, female survivors outnumbering male 7 to 1. Genetic factor? Hormonal? Need more data." Andy scrolled through location tags, trying to piece together the scale of it. The posts from major cities painted a chaotic picture, hundreds of survivors in New York, Los Angeles, Shanghai, but all isolated, scattered across vast urban landscapes. No real organization yet, just desperate attempts to connect. "Anyone alive near Brooklyn Heights?" "S O S from Miracle Mile L A, have supplies, need medical." "Twenty survivors at Pudong Hospital Shanghai, seeking others." The shock was still fresh, the posts raw with grief and disbelief. Nobody was talking about rebuilding yet. They were still counting their losses. The manuals finished downloading, and Andy forced himself to close Twitter. He needed to focus on what he could control, keeping Sarah and Daniela alive, gathering supplies, and getting out of Yosemite to a more major population center. The wider world would still be there tomorrow, whatever was left of it. He looked up at Half Dome, now silvered by moonlight. The ancient granite face was unchanged, indifferent to the apocalypse that had just played out beneath it. Somewhere in the darkness, coyotes began to howl, a sound that had always made the park feel wild and untamed. Now it felt like a reminder: nature was already moving on, reclaiming what had briefly been borrowed. Andy opened the survival manual's PDF, finding the section on "Social Collapse and Communication Strategies." The manual laid out different strategies based on mortality rates, 30%, 50%, 70%, 90%, 99%. With a grimace, he scrolled to the 99% section. "In the immediate aftermath of a >99% mortality event, social structures will be broadly erased and surviving population density will be too low for the immediate formation of antagonistic groups. Unlike smaller-scale disasters where existing social structures remain partially intact, catastrophic collapse temporarily eliminates the organizational capacity for coordinated action, hostile or otherwise. Survivors in the first weeks will be focused on immediate personal survival. During this brief window, other survivors can generally be trusted to be cooperative and helpful, as the shared experience of massive loss promotes prosocial behavior." The manual continued, further down: "Warning: This cooperative phase is temporary. As basic survival needs are met, humans will inevitably begin forming new social groups, 'tribes,' and power structures to replace those lost. Competition for resources will resume once excess pre-collapse supplies have been exhausted. Early contact and alliance formation during the cooperative phase is essential for long-term survival." Upon reading this, Andy elected to make the following post on twitter: "Ranger Andy Rhee, Yosemite National Park. Three possibly immune, North Pines/Ranger housing. Food plentiful, limited medical. Starlink operational. Main roads clear, helicopter landing sites available. Will monitor channel here & @Beacon." He followed it up with a post linking the survival manuals. He then switched to Beacon, created an account, and made the same posts. A slight rustling from inside the cabin drew his attention back to their immediate situation. He quietly stepped inside, retrieving the digital thermometer from his first aid kit. Sarah stirred slightly as he approached but didn't wake when he gently pressed the thermometer to her temple. 99 point 1, much better than this morning. He checked his own temperature next: 98 point 9. Their mild cases seemed to be resolving as quickly as they'd come on. He set his phone alarm for 5:30AM, enough time to get to Daniela's cabin by six as promised. The couch wasn't particularly comfortable, but he'd slept in far worse places. As he settled in with a spare blanket, his ranger training kicked in, categorizing the night sounds filtering through the cabin walls. Crickets. An owl. The distant yip of coyotes. Normal sounds. Safe sounds. The last thing he saw before drifting off was the green status light of the Starlink array through the window, blinking steadily like a new kind of star. The group assesses their situation, plans to leave Yosemite. Day 5, Pre-Dawn The alarm's buzz jolted Andy awake, but another sensation immediately registered, the rich aroma of fresh coffee. Sarah was curled up in his reading chair, scrolling through her phone, but as soon as she heard him stir, she immediately switched it off and turned her full attention to him. She'd changed into a new Alo Yoga set, a lavender sports bra under a white cropped tank, paired with high-waisted leggings in a matching shade. Her hair was pulled back in a messy-but-somehow-perfect bun, showing off her neck and shoulders. The fever flush was completely gone, replaced by her natural warm complexion. "Morning," she said warmly, uncurling from the chair with a practiced, fluid grace. "Made coffee. The fancy pour-over kind I found in your kitchen. Hope that's okay." Her hazel eyes met his, lingering just a moment too long as she took in his rumpled ranger uniform. "Sorry about commandeering your bed. I just meant to take a quick nap." She gave him an apologetic smile. Andy accepted the steaming mug she offered, trying not to notice how the morning light played across her toned body. "No problem. I'm used to sleeping rough. Comes with the job." Sarah tucked her legs under her on the couch next to him. The expensive fabric of her leggings caught the light as she moved, and she settled slightly closer than necessary, her knee just barely brushing his thigh. "I need to head out in about thirty minutes," Andy said, checking his phone. "There's another survivor at the park. A ranger's daughter. Her quarantine period ends at six." Sarah's eyes lit up. "Wait, really? Someone else made it?" She sat straight. "Yes. Daniela. She's fourteen, Miguel's daughter, one of our senior rangers. He;" Andy paused, remembering Miguel's final words. "He's not gonna make it." He took a deep breath. "Miguel was a big prepper. He made sure Daniela would be ready for anything. Kid's probably better prepared for this than me, honestly. He was ex-Marine, trained her in everything, survival skills, firearms, emergency medicine. I've seen her take apart and reassemble a rifle blindfolded." Sarah's eyebrows rose. "Fourteen? God." Her expression softened. "Must have been intense, growing up like that. Learning survival stuff instead of just; being a kid." "Miguel was," Andy searched for the right words. "He was paranoid I guess. We used to joke about his 'disaster preparedness' lectures." He snorted gently, irony in his voice. "And her mom?" "Passed away years ago, while Daniela was a child. Aneurysm." Andy took another sip of coffee. "Miguel basically raised her alone." Sarah held her coffee mug, pulling her legs toward her and wrapping her arms around them. "Damn, she's been through a lot already, huh? I hope she's alright." She glanced down at her designer workout wear and gave a small, self-aware smile. "Well, we should probably get ready to meet our teenage survival expert. Think she'll judge my completely impractical apocalypse wardrobe?" Andy couldn't help but smile. "Probably." He paused, then added, "Have you found Beacon yet? The Twitter alternative?" "Yeah, I was just reading through it earlier," Sarah leaned forward, coffee forgotten. "There's a virologist who's been collecting data. Says survival seems almost completely random, except for this weird seven-to-one female-to-male ratio and a slight correlation with genetic relatedness,, like if your sister survived, you had maybe a tiny bit higher chance. But besides that;" She shook her head. "No pattern. Not health status, not location or exposure level, or ethnicity, not even age. Just random genetic lottery. Either your b-cells already make the right antibodies, or they don't. I'd guess there's actually some correlation with age like there is with any disease, old immune people might still die from the mild flu symptoms we had. But; well," she sighed. "I doubt enough people are surviving in the first place right now to get that kind of data." Andy raised an eyebrow. She caught his look and shrugged, waving her hand casually. "I'm a biology major. Molecular cell biology. We learned some of this stuff last year." She continued, "Anyway, other than that it was mostly random people and groups asking for help, or offering help. It seems like all our old governments, systems, whatever, they're all gone." "Yeah. It's a whole new world out there." Andy said. "Have you thought about posting anything?" "I wasn't sure if it would be safe," Sarah admitted. "Announcing our location." "Actually," Andy said, "I already made a post last night. I was able to download survival manuals last night and they had an interesting take on it, right after something this catastrophic, people are still in shock, focused on basic survival. They don't have the resources or organization yet to be really dangerous. It's actually the best time to make contact, before people start forming new power structures and competing for resources and territory." "I see," Sarah said, working through the implications. "So what did you post?" "Just the basics. That there were survivors at Yosemite, that we have Starlink, medical supplies. That the roads are clear if anyone needs to reach us. Links to the same survival manuals." He took another sip of coffee. "Figured we should make connections while people are still helping each other." Sarah's lips curved slightly into a soft grin. "So, if you'd found me a few weeks from now, you wouldn't have been so friendly?" "Hey, don't ask me," Andy raised his hands in mock defense. "The manual knows best. Apparently I'm destined to become dangerous and territorial any day now." "Guess I met you at just the right time then," she said softly, her eyes meeting his for a moment before looking away. A quiet moment passed between them, the morning sun slowly brightening the cabin. "Where are you studying?" Andy asked, then caught himself. "Or; were you studying?" Sarah's face flickered with something complicated. "Was. Am? I;" She took a breath. "Biology at UCLA. Second year." Her voice grew quiet. "I kept searching Beacon for anyone from campus, but; nothing yet." Day 5, Morning Daniela was already sitting outside on a bench by the cabin when they arrived, military-surplus backpack at her feet, a shotgun slung over her shoulder, dressed in practical outdoor wear that made Sarah look especially out of place. She stood as they approached. Her dark hair was pulled back in a tight, no-nonsense braid, and she sat with straight-backed posture, almost too straight, like she was holding herself together through sheer will. "Ranger Rhee," she said crisply, standing as they approached. She let her eyes drift to Sarah, taking in the expensive athleisure wear and aggressively feminine curves with a quick, assessing glance that held equal parts teenage girl's envy and survival expert's dismissal. "Daniela, this is Sarah," Andy said. "She's another survivor, immune like us." Daniela gave a short nod, then launched into what felt like a rehearsed speech. "Status report: fever peaked at 101.2 three days ago, now normal temperature for 48 hours. No remaining symptoms." She gestured to her pack, her words coming slightly too fast. "I've assembled primary survival gear, in case we need to leave in a hurry. Secondary cache inside includes a hand-crank radio set, four topographical maps of Yosemite and surrounding regions, California road atlas with marked backup routes, water filtration system, three weeks of MRE, six hundred feet of para-cord in various thickness, four heavy-duty tarps." She took a quick breath, her rehearsed rhythm barely faltering. "We also have a weapons cache. One Remington 700 bolt-action with scope and 1000 rounds, one Mossberg 500 shotgun with 1000 shells, four Glock 19s with 1000 rounds of 9mm, two semi-automatic AR-15s with 5000 total rounds. RPG-7 with eight rockets. Two cases each of fragmentation grenades and flashbangs. Ten pounds of C4 with detonators. A dozen anti-personnel and anti-vehicle mines." Andy's eyes widened at the arsenal, and Sarah let out a quiet "wow." Daniela continued at top speed without acknowledging their reactions. "Two sets of Level IV body armor with trauma plates. Four tactical vests. Medical supplies organized by emergency type. Dad's old paper survival guides and field manuals. Solar oven. Basic vegetable seed packets. Shortwave radio. Antibiotics." She paused. "And a sewing machine. Manual one. For repairs." That last item seemed to crack her professional veneer slightly. She looked at Andy, her carefully maintained composure slipping. "Have you; have you seen my dad since;? He; he hasn't been responding." Andy's expression told her everything before he could speak. "Not since the clinic," he said softly. Daniela's chin trembled once, but she snapped back into her military bearing so quickly it was painful to watch, like a child playing soldier to keep the monsters away. Her voice was smaller but desperately steady when she spoke again. "What's our next move, sir?" Andy stroked his chin, considering his words carefully. "I've only got the broad strokes of a plan right now. We've got internet at my cabin, Sarah brought a military-grade Starlink array." He gave Daniela a quick overview of what they'd learned: the devastating global death toll, the seemingly random pattern of who lived and died. He mentioned the scattered posts they'd seen on Beacon, survivors in major cities trying to connect, the complete collapse of traditional infrastructure. "Here's what I'm thinking," he continued, in an attempted measured tone. "We can't stay in Yosemite. Winter's going to be tough up here, isolated, we could probably survive if we stay indoors and eat canned food or whatever we can hunt the whole time but what would that get us? We wouldn't be any closer to setting up a long term settlement, even with your father's preparations;" He paused, careful with his words. "We need to find more people. We need to probably get to a major population center. More people means more survivors means more knowledge, more resources, better chances of rebuilding something sustainable." Daniela nodded, her expression suggesting she'd already run similar calculations. "I'd say we take a day or two here first," Andy added. "Sweep the park a few more times for survivors. Gather whatever useful supplies we can find from the stores, visitor centers, other ranger stations." "Ok, that makes sense. Where's my dad?" Daniela said quietly. Andy didn't hesitate. "He's at the clinic. East wing, near the supply cabinets. Do you want us to come with you?" She shook her head. "I'll go by myself." She was already turning to leave. Andy watched her go, knowing that splitting up wasn't ideal but reasoning that the park was likely empty now except for them, and with her confident shotgun slung over her shoulder, she could probably take care of herself. "Meet us back at my cabin later," he called after her. "And keep an eye out for any large trucks or gas canisters while you're out. We'll be checking the valley store," he added. "See what we can salvage." Sarah spoke up. "I'm really glad to meet you, Daniela. It's; it's good to have another girl alive." She gave a small self-deprecating smile. "I'm obviously not as prepared as you, but; I'll do my best to not be a burden." Daniela merely nodded, wearing a worried, distant expression, and headed off toward the clinic, her stride purposeful but tense. Day 5, Morning The morning air was crisp as they headed toward the valley store, Half Dome looming above them in the clear sky. Sarah walked close to Andy's side, her earlier morning quietness replaced by an almost nervous energy. "She's so; composed," Sarah said, shaking her head in wonder. "I mean, she's cataloging military-grade weapons like she's reading a shopping list." She adjusted her designer backpack, suddenly self-conscious. "Did you see how she looked at me? I swear I could hear her mentally calculating how quickly I'd die in the wilderness." The path narrowed between some fallen trees and Sarah stepped ahead, her juicy curves swaying hypnotically as she walked. Andy gave in and let himself watch, taking in how her expensive leggings showcased her plump rear and hips rolling side to side with each step. Her ass was built for likes more than functionality but no less captivating for it. "You know, she's not actually hating on you," he said, forcing his attention back to their conversation. "She just processes everything as tactical information, it's how Miguel trained her. Analyzing strengths, weaknesses, capabilities." Sarah tucked a strand of highlighted hair behind her ear. "An RPG though? Like, an actual bazooka? Does he expect to fight a freaking tank?" "Maybe. I wouldn't put it past him." Andy replied with a shrug. "But explosives actually have a lot of use besides tanks you know. If you need to blow up a wall or car someone is hiding behind for example. In war, you're often running out of RPGs before you run out of bullets." Sarah paused, considering. "Where does a park ranger even get that kind of stuff anyway?" "Miguel had connections from his Marine days. Never talked about them much." "God, poor kid." Sarah's voice softened. "All that training, and she still lost him anyway." She was quiet for a moment, then added, "At least she knows what to do now. I'm totally useless here." Andy glanced at her. "Hey, you brought the Starlink. And the filtration system. That's not nothing." "Yeah, but I wasn't even planning to use them." She gave a small, self-deprecating laugh. "I didn't even know how they worked until yesterday. I was just supposed to make them look good in pictures." They rounded a bend in the path, the store's entrance coming into view. Sarah slowed slightly, her voice more thoughtful. "You know when Daniela was listing all that gear, there was something about the sewing machine. Do you think it was her mom's?" Andy nodded. "It was just;" She trailed off, searching for words. "Like for a second the whole soldier act dropped, and she was just a kid who lost her parents." Andy nodded, remembering the slight tremor in Daniela's voice at that moment. They reached the store's entrance, its glass doors standing partially open. Sarah instinctively moved closer to Andy's side as they faced the quiet and empty building. The morning light streamed through the store's high windows and skylights, illuminating neat aisles of outdoor gear and camping supplies. Everything was still in its place, the pandemic had moved too quickly for panic buying or looting. The store felt frozen in time, like its staff had simply stepped out for lunch and never returned. "Boots and outdoor gear are in the back left," Andy said, gesturing. "Look for something waterproof, with good ankle support. And grab some proper hiking pants, the kind with zip-off legs and plenty of pockets. I'm going to check our food supplies in the storage room." Sarah nodded, already moving toward the clothing section. "I'll try to channel my inner Daniela. No more Instagram fashion choices." Andy headed to the back of the store, past rows of camping equipment and climbing gear. The storage room door was locked, but a few solid swings with the fire axe he'd retrieved from its wall mount made short work of the deadbolt. Inside, he swept his gaze across rows of shelves stacked with boxes and crates. His shoulders relaxed as he took inventory, hundreds of cans of chili, soup, and vegetables. Sealed packages of dried fruits and trail mix. Energy bars by the case. Enough preserved food to feed a small group for months, maybe longer if they rationed carefully. Way more than they could possibly take with them. Returning to the main area, Andy methodically selected gear from the high-end section, a rugged Carhartt jacket, some water-resistant hiking pants, and a pair of well-reviewed Merrell boots to supplement his ranger gear. He grabbed a Leatherman Wave+ multi-tool, a pair of Vortex binoculars, and several high-end headlamps and lanterns with spare batteries. Making his way to the women's section, he found Sarah studying her reflection in a full-length mirror. She'd changed into a pair of olive-green tactical pants that, despite their utilitarian design, hugged her curves perfectly where they cinched at her waist. A cropped camo compression top showed off her toned midriff while providing actual support and protection. Black Salomon hiking boots replaced her pristine Nikes, and an Arc'teryx jacket in sleek black completed the ensemble. She'd managed to find gear that was both practical and flattering, the pants especially seemed designed to enhance rather than hide her natural assets. She turned slightly, checking the fit from different angles. "What do you think?" she asked, adjusting the jacket. "The pants are actually really comfortable. And this top breathes really well." She moved through a few stretches, testing the range of motion, the gear moving naturally with her body, causing her ample bust to jiggle pleasantly. Andy tried not to stare. "Those boots are perfect," Andy said, nodding approvingly. "Salomon makes some of the best. They'll last for years if you take care of them." Sarah bent down to grab another small pile of clothes from the floor. "I grabbed some things for Daniela too." "Good idea. How do you know what size she is?" Andy asked, eyeing the stack of clothing. Sarah laughed, a glint in her eyes. "Trust me, I can tell. It's a girl thing." She folded the clothes with efficiency, tucking them into a rugged canvas duffel bag and her new backpack. "Plus, everything I picked has adjustable waists and drawstrings. She'll be able to make it work." Day 5, Evening The crackling of the campfire filled the silence between them as they sat in front of Andy's cabin, the flames casting flickering shadows across their faces. Steam rose from their bowls of rehydrated beef stew. Daniela sat cross-legged on a log, her new pants and boots looking almost too perfect, still creased from their packaging. Her dark hair was pulled back in a fresh braid, but a few strands had escaped during the day's labor, clinging to her neck. Her spoon moved mechanically from bowl to mouth, her expression distant and detached. The blisters on her hands from digging the grave were hidden beneath fingerless gloves. Sarah sat on a camp chair, somehow making even that look graceful. She'd changed into black leggings and an oversized ranger station sweatshirt she'd found, her hair pulled up in a messy bun. Her eyes kept flicking to Daniela. Each time she caught herself watching too long, she'd look away quickly, taking small, careful bites of her stew. Andy was hunched over his phone, the light illuminating his face as he scrolled through Beacon posts. The Starlink array hummed softly behind them, its status lights reflecting off the cabin windows. "More reports coming in from the Bay Area," he said finally, breaking the silence. "Sounds like they're organizing some kind of central meeting point in San Francisco. Using the Presidio as a base camp." Sarah nodded, seizing the conversation attempt. "Makes sense. I've been there before. It's really pretty." Daniela continued eating mechanically, showing no response. The fire popped loudly, sending up a shower of sparks. Daniela's hand dropped down to her holster before she realized what she was doing, then went back to her food. Her face remained carefully blank, but her knuckles whitened around her spoon. Sarah's eyes met Andy's over the fire. She opened her mouth as if to say something, then closed it again, turning her attention back to her own bowl. Andy set his phone down, choosing his words carefully. "We should probably talk about where we're heading. We've got some options to consider." Sarah chimed in again. "Yeah, like you said, the Bay Area seems to be organizing faster than anywhere else," she offered. "And my parents live in Palo Alto." She let the thought hang unfinished. "L A is an option, too;" Andy said, for now trying to brush past thoughts of Sarah's lost loved ones, and by extension his own as well. "More spread out, might be easier to find supplies. And Sarah you know the area pretty well I assume?" She nodded. He continued, thoughtful. "The Central Valley has farming potential, but no real organization showing up yet. Portland and Seattle are possibilities, but that's a long trek north. If we want to go south, Vegas and Phoenix also exist." The logo of Fallout New Vegas appeared in his mind's eye. "South is out," Daniela spoke suddenly, her voice flat. "Can't farm without major irrigation infrastructure. Nobody's maintaining those systems anymore." It was the most she'd said since returning from the clinic. Andy nodded. "True. We could probably gather enough fuel to make it across the country if we wanted to risk it, but;" "That's a lot of unknown territory to cover," Sarah finished. She pulled out her phone, scrolling through Beacon posts. "Though from what I'm seeing, the East Coast isn't doing any better than we are. Maybe worse, winter is coming." "The cold and snow would be a major disadvantage," Daniela said, her voice taking on the precise tone she used when reciting her father's lessons. "Increased resource consumption, limited farming windows, higher risk of mechanical failures in vehicles and equipment." She set her empty bowl aside. "California's the logical choice. Better climate, more stable growing seasons." "Agreed," Andy said. Daniela seemed to find stability in talking about this. "So that brings us back to L A versus the Bay." "The Bay Area is the only logical choice between the two." Daniela began ticking points off on her fingers, echoing discussions that had happened many times before. "The peninsula provides natural defensive positions. Multiple deep-water harbors for future maritime operations. Significantly more unpaved space for urban agriculture compared to the L A concrete sprawl." She continued briskly. "Plus, direct river access to the Central Valley farming regions around Stockton, where there's plenty of water for farming. From L A, you'd have to cross the Transverse Ranges to get to Bakersfield- that's a major liability for supply lines." Her voice took on an edge of disdain. "And farming that far south in the Valley isn't going to be viable anymore anyway, they're almost as reliant on irrigation as Phoenix or Las Vegas." She shook her head decisively. "The L A positioning is completely unsustainable. Anyone there should be evacuating to the Bay immediately." Andy nodded slowly, impressed but not surprised by the depth of analysis. He'd seen this level of preparation in everything Miguel and Daniela did. He glanced at Sarah, eyebrows raised in silent question. Sarah gave one of her small, self-deprecating smiles. "Don't look at me for expertise. The most strategic thinking I've ever done is planning photoshoots." She tucked a loose strand of hair behind her ear. "But Daniela's logic makes perfect sense. I mean, it's clearly been; thoroughly thought through." "The Bay it is then," Andy said, straightening up. "We should take two days to prepare; we can stock up on food, supplies, and then pick cars. There are plenty of abandoned vehicles in the valley, we'll need time to find the right ones and load them properly. It's not a long drive, but we should be thorough." He looked between them both. "We leave in three days." To be continued. Based on a post by the hospital, for Literotica.
Today, synthetic bacteriophages, a breakthrough vaccine for TB, and how unpicking the pathways used to make antibiotics are helping scientists to combat rising rates of antimicrobial resistance around the world... Like this podcast? Please help us by supporting the Naked Scientists
Join Marin H. Kollef, MD in the first of 3 podcasts from our live event, “The Plot (and Sputum) Thickens: Encountering Carbapenem Resistance in Critically Ill Patients” to learn how to optimize antimicrobial regimens and develop evidence-based antibiotic management plans for complex infections caused by carbapenem-resistant bacteria. Topics covered in this segment includeAntimicrobial resistance mechanismsDiagnostic strategies for identifying resistanceAntibiotic selection strategiesPreferred and alternative antibiotics according to guideline recommendationsPresenter:Marin H. Kollef, MDVirginia E. and Sam J. Golman Chair in Respiratory Intensive Care MedicineProfessor of MedicineDivision of Pulmonary & Critical Care MedicineDirector, Critical Care ResearchDirector, Respiratory Care ServicesWashington University School of MedicineSt Louis, MissouriLink to full program and downloadable slides:CCO: https://bit.ly/4omLRLBProCE: https://bit.ly/4pA1Xm4Get access to all of our new podcasts by subscribing to the Decera Clinical Education Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika VijayIt is the New SEASON 12, namely "YEAR END SPECIAL SEASON"In this episode, I will be covering all about Antibiotics ans AMR trends in 2025!Podcast is for all- doctor, pharmacologist, med student, pharmacist and laymen interested in science of Pharmacology, drugs and medicinesMy podcast is featured in "TOP 20 PHARMACOLOGY PODCASTS"- Check the link here:https://podcast.feedspot.com/pharmacology_podcasts/My podcast is featured in " 40 BEST INDIA EDUCATION PODCASTS"- Check the link here:https://podcast.feedspot.com/india_education_podcasts/My podcast is featured in "BEST SCIENCE PODCASTS"- Check the link here:https://podcasts.feedspot.com/india_science_podcasts/My podcast is featured in "BEST INDIAN MEDICAL PODCASTS". Check the link here:https://podcasts.feedspot.com/india_medical_podcasts/?feedid=5503395For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine."Pharmacology Further" E-Newsletter and Podcast:The links for these are at all my websites and specifically:Link for E-Newsletter: https://pharmacologyfurther.substack.com/Link for the E-Newsletter Podcast: https://www.pharmacologyfurther.comIt actually contains lot of updates about the medical sciences, drug information and my podcast updates also.You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!!Please leave Review on Apple podcasts!My E-Newsletter sign up at Substack!Connect on Twitter & Instagram!My books on Amazon & Goodreads!
When it comes to career advancement, putting in hours beyond the clinic day can make the biggest difference, says DEF Advisory Council member Andrea Nguyen, DMSc, MPAS, PA-C. Cooperation and support are also key, she says. And it's also important not to sweat the small stuff. Plus, Lisa Swanson, MD provides an update on oral therapy for acne.Like what you're hearing? Want to learn more about the Dermatology Education Foundation? Explore assets and resources on our website.
In this episode, Dr. Tony Ebel tackles one of the most concerning issues in pediatric healthcare: the unnecessary prescription of antibiotics to children. With 30% of antibiotics prescribed to kids being unnecessary (according to CDC research), Dr. Tony breaks down the real consequences this has on children's long-term health. He explains how antibiotics disrupt the gut microbiome, nervous system, and immune function, leading to increased risks of asthma, allergies, ADHD, and anxiety. Most importantly, he reveals that the majority of ear, sinus, and respiratory infections are viral—not bacterial—meaning antibiotics don't even help. Dr. Tony explores the root cause of these infections (poor nervous system function and drainage), and how Neurologically-Focused Chiropractic Care addresses the actual problem rather than masking symptoms.Key Topics & Timestamps[00:01:00] The shocking truth: 30% of antibiotics prescribed to kids are unnecessary[00:04:00] The pediatrician paradox: 85% agree on wait-and-see, but only 33% follow it[00:06:00] How antibiotics disrupt the gut-brain connection and microbiome[00:08:00] Understanding the vagus nerve: the most important nerve in the body[00:10:00] The root cause revealed: respiratory infections are really a "plumbing problem"[00:12:00] Dr. Tony's personal story: four kids, zero antibiotics, zero ear infections-- Register for the FREE 'Calming The Sensory Storm' Webinar HERE Follow us on Socials: Instagram: @pxdocs Facebook: Dr. Tony Ebel & The PX Docs Network Youtube: The PX Docs For more information, visit PXDocs.com to read informative articles about the power of Neurologically-Focused Chiropractic Care. Find a PX Doc Office near me: PX DOCS DirectoryTo watch Dr. Tony's 30 min Perfect Storm Webinar: Click Here
Antibiotics won't help if you have a cold or flu. Tuesday was European Antibiotic Awareness Day, and the Irish Pharmacy Union marked the occasion by urging us not to use them for viral infections, as they can cause more harm than good. It can mean they're less effective when you do need them, and can cause side effects like skin rashes, nausea, or diarrhoea. Alan Morrissey has been speaking about this with Feidhlim Hillery of Hillery's Pharmacy in Shannon town. Photo (c) Towfiqu Barbhuiya via Canva
Dr Jason Newland visits the studio as we consider antimicrobial medications and the stewardship programs aimed at saving them. Antibiotics emerged as miracle drugs in the early 20th Century. However, these life-saving treatments can lose their effectiveness if not used correctly. Tune in to learn more, including the role each of us can play in keeping them working!
Episode 12 - How to Restore the Microbiome After C-section and Antibiotics! Dr. Katri Korpela reveals what science says and how to support a healthy start. Disclaimer: Please note that all information and content on the UK Health Radio Network, all its radio broadcasts and podcasts are provided by the authors, producers, presenters and companies themselves and is only intended as additional information to your general knowledge. As a service to our listeners/readers our programs/content are for general information and entertainment only. The UK Health Radio Network does not recommend, endorse, or object to the views, products or topics expressed or discussed by show hosts or their guests, authors and interviewees. We suggest you always consult with your own professional – personal, medical, financial or legal advisor. So please do not delay or disregard any professional – personal, medical, financial or legal advice received due to something you have heard or read on the UK Health Radio Network.
We're marking World Antimicrobial Resistance (AMR) Awareness Week 2025 with an episode dedicated entirely to antibiotics, the medicines we rely on every day and the ones we need to protect. We're joined by Caroline Chen, a senior antimicrobial stewardship pharmacist and project officer at the Royal Melbourne Hospital, for a deep dive into all things antibiotics. Together, we walk through the ABCs of commonly used antibiotics, or more accurately the B through T, including beta-lactams, clindamycin, doxycycline, macrolides, metronidazole, nitrofurantoin, quinolones, rifampicin and trimethoprim. This episode highlights how these medicines work and when we use them and key counselling points. Antibiotics are a finite resource, and understanding them is one of the most powerful tools we have to preserve their effectiveness for the future.
Welcome to today's ICYMI, where we kick off the week with a quick game-changing tip from one of our guests that you might have missed.Flu season is upon us, so we're throwing it back to this helpful advice from Abbey Sharp on boosting your metabolism, and restoring your gut health after dysbiosis from antibiotics. Did you know 70% of our immune system is housed in our gut? We cover the surprising link between your gut microbiome and your immune system, mental health, skin, hormones, and more, and why fibre is the unsung hero of gut health and immunity.Abbey is a Registered Dietitian (RD), a cookbook author, a TV nutrition expert, a YouTuber, host of the podcast Bite Back, and the founder of Abbey's Kitchen. She dismantles diet culture with science and sass, and her core philosophy is that a pleasurable relationship with food, your body and your self is the fundamental secret to good health.Listen to our full episode with Abbey. Tune in every Monday for an expert dose of life advice in under 10 minutes.Follow Abbey:Abbey's KitchenAbbey's Podcast: Bite BackOn IG: @abbeyskitchen/ Sign up for our monthly adulting newsletter:teachmehowtoadult.ca/newsletter Follow us on the ‘gram:@teachmehowtoadultmedia@gillian.bernerFollow on TikTok: @teachmehowtoadultSubscribe on YouTube
Troy Kinne’s heart is in the right place. As in, it’s on the wrong side.
This episode kicks off Pharmacology November with a focused review of antibiotics that matter most for your boards and practice. I walk through the major drug classes you need to know breaking down their key uses, safety profiles, and those crucial exceptions that show up on exams. From understanding why Augmentin works when amoxicillin fails to knowing when doxycycline trumps all other options (even in pregnancy), this content review covers the practical decision-making you'll face daily. By the end, you'll have a clearer framework for choosing first-line treatments and knowing exactly when and why to reach for alternatives. Get full show notes, transcript, and more information here: https://blog.npreviews.com/antibiotics-classes/ Follow us on Instagram: instagram.com/smnpreviewsofficial
Longevity for modern women isn't about doing more—it's about choosing what matters. Today with Dr. Vincent Pedre — an integrative physician, gut-health expert, and author of The GutSMART Protocol. We connect meditation, mitochondria, and gut integrity into one aligned approach. You'll learn why "leaky gut" is nuanced (not clickbait), how microplastics quietly erode your defenses, when biohacking tips into cellular overdrive, and why breastfeeding + active detox don't belong in the same season. Expect calm clarity and practical shifts that respect female biology, nervous-system health, and real life. WE TALK ABOUT: 08:16 - How meditation changed a Type-A med student into "the Zen guy" and why calm doctors save lives 16:50 - Antibiotics, IBS, and the personal gut-health journey that shaped a career 19:35 - Food shifts that actually help: Organic eating, fermented foods, and L-glutamine to "seal and heal" 22:10 - "Leaky gut" clarified: Imperfect tests, useful clues, and what to measure 25:30 - Microplastics from hot coffee cups and takeout: how they damage the gut's mucus layer 28:15 - Wellness without rigidity: The 80/20 that reduces stress 33:55 - Mitochondrial testing insights: When high-performers are actually over-driving their cells 40:10 - Building a truly low-toxin coffee and why micro-habits drive macro health 45:00 - Coffee enemas for migraines and detox: what the clinician actually sees 51:14 - Sauna for longevity and detox: Dose, frequency, and why infrared helps 58:00 - Breastfeeding + detox: Why mobilizing toxins is a no for now 1:03:55 - Why medicine should be gut-centric before anything "muscle-centric" SPONSORS: Join me in Costa Rica for Optimize Her, a 5-night luxury women's retreat in Costa Rica with yoga, healing rituals, and biohacking workshops—only 12 spots available. Feeling bloated, tired, or hormonally off? Try BiOptimizers — supplements that actually absorb and work for women's health. Get 15% off at bioptimizers.com/biohackingbrittany with code BIOHACKINGBRITTANY. RESOURCES: Trying to conceive? Join my Baby Steps Course to optimize your fertility with biohacking. Free gift: Download my hormone-balancing, fertility-boosting chocolate recipe. Explore my luxury retreats and wellness events for women. Shop my faves: Check out my Amazon storefront for wellness essentials. Dr. Vincent Pedre's website and Instagram LET'S CONNECT: Instagram, TikTok, Facebook Shop my favorite health products Listen on Spotify, Apple Podcasts, YouTube Music
Do you routinely order prophylactic antibiotics at time ofsecond-degree laceration repair? Is there data for that? While the use of prophylacticantibiotics “is reasonable” (per ACOG PB 198) for OASIS lacerations, what doesthe data look like for second degree lacs? Well, the answer is both supportiveAND non-supportive of that practice! In this episode, we will cover a brand newpublication (RCT) from BMJ on this very issue, and also highlight a meta-analysisfrom Plos One (May 2025) that also examined this question. Listen in fordetails!1. ACOG PB 1982. Armstrong H, Whitehurst J, Morris RK, HodgettsMorton V, Man R; CHAPTER group. Antibiotic prophylaxis for childbirth-relatedperineal trauma: A systematic review and meta-analysis. PLoS One. 2025 May9;20(5):e0323267. doi: 10.1371/journal.pone.0323267. PMID: 40344566; PMCID:PMC12064200.3. Risk of infection and wound dehiscence after useof prophylactic antibiotics in episiotomy or second degree tear (REPAIR study):single centre, double blind, placebo controlled randomised trial. BMJ 2025; 391doi: https://doi.org/10.1136/bmj-2025-084312 (Published 29 October 2025): BMJ2025;391:e084312
Send us a textWelcome back Rounds Table Listeners! We are back today with a Classic Rapid Fire episode. This week, Drs. Mike and John Fralick discuss two recent papers: the effects of spironolactone on heart failure and cardiovascular death in patients undergoing maintenance dialysis, and antibiotic prophylaxis in patients with cirrhosis and upper gastrointestinal bleeding. Two papers, here we go!Spironolactone versus placebo in patients undergoing maintenance dialysis (ACHIEVE): an international, parallel-group, randomised controlled trial (0:00 – 7:19)Prophylactic Antibiotics for Upper Gastrointestinal Bleeding in Patients With Cirrhosis: A Systematic Review and Bayesian Meta-Analysis (7:20 – 15:08)And for the Good Stuff (15:09 – 17:51):The $500m slugger who helped Canada get to the World SeriesClinical practice guidelines one-pagers coming soon to Trial Files: https://trialfiles.substack.com/Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods
Each year, 4.95 million deaths worldwide are linked to antimicrobial resistance, making drug-resistant infections one of the greatest threats to health Research shows that taking common painkillers like ibuprofen or acetaminophen while on antibiotics speeds up bacterial mutations that make infections harder to treat Resistance levels in E. coli jumped as much as 64-fold when exposed to both antibiotics and over-the-counter painkillers, and the resistance spread to multiple antibiotic classes Older adults in long-term care facilities face the highest risk because they often take multiple medications daily, creating the perfect environment for resistant bacteria to thrive Choosing natural pain relief options and limiting unnecessary antibiotic use are simple steps to protect yourself from fueling dangerous superbugs
Lost dog, happy ending. Counting to sleep. Melatonin risk. Do you need to rinse your dishes? Food expiration. Mushrooms or meat? Texas A&M Athletics. Antibiotics.
TSW—Topical Steroid Withdrawal—when you're hooked on steroid creams for a skin condition and can't get off; Can diet, supplements, or Traditional Chinese Medicine help eczema? Strange bedfellows—when your hospital assigns you a homicidal roommate; Every step you take may reduce your risk of dying; Vitamin D and Omega-3 supplements reduce risk of autoimmune conditions; How long to curtail fish oil before a medical procedure or surgery? Supplements for neuropathy.
In this follow-up to his deep dive on protein, Darin exposes the other side of the protein story: where your food comes from, what's really in it, and how the system itself affects your health, the planet, and the animals. From factory farm contamination to antibiotic resistance, industry lobbying, and why plants still win on every level — Darin breaks down the research, ethics, and environmental data so you can make conscious choices that fuel a truly SuperLife. What You'll Learn [00:00] Welcome + sponsor message: plastic waste, conscious products, and Bite Toothpaste [02:47] Introduction — the real protein conversation continues [03:00] The source of your food matters more than macros [03:10] Contamination, ethics, and the reality of factory farming [03:30] Stewardship vs. dominion — a call for responsibility [04:01] EPA data: confined animal operations and environmental chaos [05:00] Foodborne illness: salmonella, E. coli, and what contamination really means [05:57] Antibiotics, resistance, and hormones in animal agriculture [06:42] Persistent pollutants (PFOAs) showing up in food and milk [07:10] How animal feed (soy and corn) drives ecological damage [07:57] USDA marketing boards + industry lobbying against plant alternatives [08:38] Darin's 17 years vegan — data and lived experience [09:00] The numbers: amino acids, LDL, fat swaps, and longevity [09:47] Common plant-based protein myths answered [12:59] Patreon message — upgrade your operating system and join the tribe [14:03] The cancer connection: processed and red meat research [14:47] Iron, B12, and what vegans actually need to know [15:37] Soy, testosterone, and thyroid myths debunked [16:08] Protein quality: why mixing plant foods covers all bases [16:31] Feeling better on moderate meat? Understanding the trade-offs [17:18] Substitution data: even small swaps improve health outcomes [17:57] Processed vs. ultra-processed: why Beyond Meat isn't the enemy [18:09] Environmental impact: why beef's footprint dwarfs plant protein [19:05] Food miles myth — what you eat matters more than distance [19:29] Cost and accessibility: the cheapest protein sources are plants [20:08] Contamination and antibiotic resistance rising annually [21:03] Anti-nutrients and the myth of plant dangers [21:47] Real-world evidence: fiber, polyphenols, and legume-based longevity [22:00] Final recap — all essential amino acids come from plants [22:17] Strongest evidence: plant protein wins ethically, environmentally, and scientifically Thank You to Our Sponsors: SuperLife Patreon: Go towww.patreon.com/DarinOlien and sign up to start changing your life today Bite Toothpaste: Go to trybite.com/DARIN20 or use code DARIN20 for 20% off your first order. Connect with Darin Olien: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences Platform & Products: superlife.com Key Takeaway "All plants contain all essential amino acids. The more you swap red meat for plants, the longer, stronger, and cleaner your life becomes."
TODAY ON THE ROBERT SCOTT BELL SHOW: Texas Sues Tylenol, Acetaminophen Risky Behavior, Airlines Pesticides, SNAP Crisis, Phellandrium Aquaticum, RFK Astroturf Exposed, Farmers Urge USDA Reform, RFK Ultra-Processed Foods, EPA Ignores MAHA Moms, Parasites, Antibiotics, and MORE! https://robertscottbell.com/texas-sues-tylenol-over-pregnancy-risk-acetaminophen-induces-risky-behavior-airlines-spray-pesticides-in-cabin-welfare-check-crisis-phellandrium-aquaticum-rfk-astroturf-exposed-farmers-urge-usda/ https://boxcast.tv/view/texas-sues-tylenol-acetaminophen-risky-behavior-airlines-pesticides-snap-crisis-rfk-astroturf-exposed---the-rsb-show-10-29-25-mq8qvl37hqnnxaannuau Purpose and Character The use of copyrighted material on the website is for non-commercial, educational purposes, and is intended to provide benefit to the public through information, critique, teaching, scholarship, or research. Nature of Copyrighted Material Weensure that the copyrighted material used is for supplementary and illustrative purposes and that it contributes significantly to the user's understanding of the content in a non-detrimental way to the commercial value of the original content. Amount and Substantiality Our website uses only the necessary amount of copyrighted material to achieve the intended purpose and does not substitute for the original market of the copyrighted works. Effect on Market Value The use of copyrighted material on our website does not in any way diminish or affect the market value of the original work. We believe that our use constitutes a 'fair use' of any such copyrighted material as provided for in section 107 of the U.S. Copyright Law. If you believe that any content on the website violates your copyright, please contact us providing the necessary information, and we will take appropriate action to address your concern.
Antibiotics are very often overprescribed... And new research shows they may actually worsen outcomes during the flu. On today's episode, we dive into studies revealing how antibiotics disrupt your gut microbiome, weaken your immune system, and may increase complications from influenza. We also explore the critical connection between gut health, inflammation, and immune function and why a balanced microbiome is key for your overall wellness. So join me on today's Cabral Concept 3553, where we explore why antibiotics taken for influenza may lead to increased deaths and what you can do instead to support your health naturally. Enjoy the show! - - - For Everything Mentioned In Today's Show: StephenCabral.com/3553 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!
Dr. Hoffman continues his conversation with Dr. Alexandra Shustina, NYC's and Miami's premier Integrative board-certified Gastroenterologist and gut health specialist, an expert in the gut microbiome and its role in health and wellness.
In this episode of the Intelligent Medicine podcast, Dr. Ronald Hoffman is joined by Dr. Alexandra Shustina, a distinguished integrative gastroenterologist based in New York City and Miami. They delve into Dr. Shustina's journey from conventional to integrative medicine, the importance of addressing the microbiome, and holistic approaches to treating gastrointestinal ailments like IBS, Crohn's disease, and ulcerative colitis. Dr. Shustina shares her insights on diet, the impact of stress, and the role of supplements and herbal remedies. She discusses the significance of personalized care, visceral manipulation, and mind-body techniques in promoting gut health. The episode also touches on the rising incidence of gastrointestinal cancers in young people and the potential benefits of proactive, integrative healthcare approaches.
Ep.102- Supporting The Gut Through Antibiotics, Candida Overgrowth by Erin Kenney, MS, RD, LDN, HCP
On this episode of Vitality Radio, Jared tackles a topic that affects nearly half of adults over 50 — diverticulosis and diverticulitis. What starts as small “colon pouches” can lead to serious inflammation and infection, yet conventional medicine often reaches for antibiotics, painkillers, or surgery instead of true healing. Jared explains how to naturally support the colon before problems arise, calm inflammation during a flare, and rebuild long-term gut health. You'll learn how specific natural compounds—like aloe vera, Boswellia, and spore-based probiotics—help cool and restore the intestinal lining. Jared also shares a comprehensive natural protocol featuring Back On Tract, Aloe, and soothing botanicals designed to bring lasting comfort and resilience to the gut. If you or someone you love struggles with digestive flare-ups or wants to prevent them, this episode offers practical, real-world steps to strengthen and protect your gut naturally.Products:Back on TractAloe Life Stomach Plus FormulaSolaray Peppermint Oil Capsules with Rosemary and Thyme OilBosMed Intestinal Bowel SupportVitality Nutrition Nano-SilverSolaray Oil of OreganoSolaray Slippery ElmSolaray Marshmallow RootMagnesium BisglycinateMagnesium CitrateYerba Prima Daily Fiber CapsRegulari-TLifeSeasons Leg Veins Tone‑R™ (Vitality Radio POW! Product of the Week Over 40% off with PROMO CODE: POW14)Visit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.
What if the key to healing your body—and your mind—starts in your gut?Could anxiety, low energy, and inflammation all trace back to the same place?And what if the secret to balance isn’t adding more, but restoring what’s already within you? In this episode of A Really Good Cry, Radhi sits down with microbiologist and gut health expert Kiran Krishnan for a fascinating, eye-opening conversation on how our gut influences everything—from digestion and mood to immunity and mental clarity. Kiran breaks down complex science into simple truths about how the body really works. He shares why our gut is like a living rainforest, how stress and antibiotics disrupt its balance, and what it actually takes to rebuild harmony within your system. Together, Radhi and Kiran explore how small daily habits—like eating slowly, adding bitters, and embracing probiotics—can shift not just your digestion, but your entire sense of well-being. This isn’t just a conversation about gut health. It’s about reconnecting with the natural intelligence of your body and remembering that healing doesn’t have to be complicated—it just has to be conscious. In this episode, you’ll learn: Why 99.9% of microbes in your body are helping, not harming you How stress directly impacts your digestion and mental health What antibiotics really do to your microbiome—and how to recover Why slow eating and digestive bitters can transform how you feel The connection between gut health, mood, and better sleep How to create a daily routine that supports balance from the inside out If you’ve been feeling tired, foggy, or disconnected from your body, this episode is your reminder: healing doesn’t start in the mind—it starts in the gut. Follow Kiran:https://www.instagram.com/kiranbiome/https://justthrivehealth.com/https://www.instagram.com/justthrivehealth/ Follow Radhi:https://www.instagram.com/radhidevlukia/https://www.youtube.com/channel/UCxWe9A4kMf9V_AHOXkGhCzQhttps://www.facebook.com/radhidevlukia1/https://www.tiktok.com/@radhidevlukiaSee omnystudio.com/listener for privacy information.
The Elective Rotation: A Critical Care Hospital Pharmacy Podcast
Show notes at pharmacyjoe.com/episode1071. In this episode, I'll discuss whether a nasal MRSA screen is useful for choosing antibiotics in critically ill patients with an intraabdominal infection. The post 1071: Can a nasal MRSA screen be useful for choosing antibiotics in critically ill patients with an intra abdominal infection? appeared first on Pharmacy Joe.
Something new is emerging in the world of digital dating. Chatfishing is a new word coined for when a person uses AI-generated messages to disguise or enhance their appeal on dating apps, only to show up with a completely different persona in real life! To get into the impact of it, Jennifer is joined by international relationship coach Hunt Etheridge and psychologist Noha El Khatib. One in six bacterial infections worldwide is now resistant to common antibiotics according to a new data released by the WHO. Dr Howard Podolsky, CEO of Johns Hopkins Aramco Healthcare, explains what it means for all of us. Two women are on a mission to rethink what a truly an inclusive workplace culture actually looks like in a country and multicultural as the UAE, and we turn to Haus & Haus for all your property questions. See omnystudio.com/listener for privacy information.
Matters Microbial #112: Bacterial Size, Stress, and Antibiotic Resistance October 17, 2025 Today Dr. Petra Levin, the George and Irene Freiberg Professor of Biology at Washington University in St. Louis joins the #QualityQuorum to discuss her work with bacterial cell size, environmental stress on bacteria, and antibiotic resistance. Host: Mark O. Martin Guest: Petra Levin Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An overview of the periplasm, found in Gram negative bacteria. An overview of beta-lactam antibiotics. The field of quantitative microbiology. An overview of B. subtilis. An overview of E. coli. An overview of Klebsiella. The biography of Barbara McClintock, “A Feeling for the Organism.” A video explanation of the lac operon of E. coli. The LTEE program (Long Term Evolution Experiment) founded by Dr. Rich Lenski. The nomenclature of monoderm and diderm bacteria. A video explanation of peptidoglycan in bacteria. Penicillin binding proteins (PBP) and antibiotic resistance. A video about cell division in E. coli. A famous article coauthored by Dr. Elio Schaechter that describes cell growth and cell size in bacteria. A related article by Dr. Levin and colleagues. An overview of ESKAPE bacteria. An article from Dr. Levin's research group describing the relationship between pH and antibiotic resistance. An article about persister cells and their relevance to antibiotic resistance. Dr. Levin's faculty website. Dr. Levin's very interesting laboratory website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
Jim Collins, Termeer Professor at MIT, unveils his AI-powered project that has discovered several new antibiotics, effective against resistant strains and often employing entirely new mechanisms of action. He details how their refined multi-step AI process, even with small datasets and modest compute, can efficiently screen vast chemical spaces to identify promising drug candidates. This breakthrough offers a realistic and affordable path to tackling the staggering antibiotic resistance crisis, which currently claims over a million lives annually. Collins argues this practical application of AI represents a transformative win for humanity, often overlooked amidst the focus on AGI. Sponsors: AssemblyAI: AssemblyAI is the speech-to-text API for building reliable Voice AI apps, offering high accuracy, low latency, and scalable infrastructure. Start building today with $50 in free credits at https://assemblyai.com/cognitive Claude: Claude is the AI collaborator that understands your entire workflow and thinks with you to tackle complex problems like coding and business strategy. Sign up and get 50% off your first 3 months of Claude Pro at https://claude.ai/tcr Linear: Linear is the system for modern product development. Nearly every AI company you've heard of is using Linear to build products. Get 6 months of Linear Business for free at: https://linear.app/tcr AGNTCY: AGNTCY is dropping code, specs, and services. Visit AGNTCY.org. Visit Outshift Internet of Agents Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive PRODUCED BY: https://aipodcast.ing CHAPTERS: (00:00) About the Episode (04:30) Introducing Jim Collins (05:26) Antibiotic Resistance Primer (14:04) The Antibiotic Market Failure (18:45) AI Discovers Halicin (Part 1) (18:51) Sponsors: AssemblyAI Ad 1 | Claude (22:11) AI Discovers Halicin (Part 2) (30:58) The Economics of Discovery (39:10) Inside the AI Architecture (Part 1) (39:17) Sponsors: Linear | AGNTCY | Shopify (43:47) Inside the AI Architecture (Part 2) (01:00:13) Human-in-the-Loop Discovery (01:12:12) Novel Mechanisms & Properties (01:19:02) Future Applications & Risks (01:27:01) A Call to Action (01:28:04) Outro
This year's Nobel Prize in Physiology or Medicine went to three people whose combined discoveries outlined the role of the peripheral immune system—how the immune system knows to attack just foreign invaders and not its own tissues and organs. But when the phone rang for Shimone Sakaguchi, Mary E. Brunkow, and Fred Ramsdell, only two of them picked up.Host Ira Flatow talks with Nobel Prize winner Fred Ramsdell, co-founder and scientific advisor at Sonoma Biotherapeutics.Plus, Ira talks with bioengineering professor César de la Fuente, who looks for solutions to the antibiotic resistance crisis in unexpected places. Now, he's used AI to help identify promising antibiotic candidates lurking in ancient archaea, small organisms that can survive some of the most extreme conditions in the world.Guests:Dr. Fred Ramsdell is the co-founder and scientific advisor at Sonoma Biotherapeutics.Dr. César de la Fuente is an associate professor of bioengineering at the University of Pennsylvania.Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
Your genetics influence which fungi grow in your gut, and these fungi directly affect your risk for chronic conditions like heart disease Researchers discovered 148 genetic variants linked to nine groups of gut fungi, proving that your DNA helps shape your gut health Antibiotics kill bacteria but leave fungi untouched, allowing harmful fungal strains to overgrow and increase disease risk Two people eating the same foods can have very different health outcomes because genetic differences decide which fungi thrive in their gut Gut microbiome patterns, including fungi and bacteria, are strong predictors of cardiovascular disease risk, yet most clinics still ignore this critical factor
Did you know the trillions of microbes in your gut might shape everything from your immune system to your mental health—and even how you recover after an infection?
Podcast summary of articles from the August 2025 edition of the Journal of Emergency Medicine from the American Academy of Emergency Medicine. Topics include pediatric sedation, trauma triage, SVT medications, antibiotics in surgery, levothyroxine overdose, and animal bites. Guest speaker is Dr. Cory Ohradzansky.
Dr. Hoffman continues his conversation with Jane Jansen, a natural and holistic practitioner from the Tree of Life Wellness Center in Massachusetts, on the importance of the microbiome, particularly the role of probiotics, in maintaining health.
Jane Jansen, a natural and holistic practitioner from the Tree of Life Wellness Center in Massachusetts, focuses on the importance of the microbiome, particularly the role of probiotics, in maintaining health at all life stages. They explore the benefits of specific probiotic strains, the impact of prebiotics and postbiotics, and the use of Dr. Ohhira's Probiotics. Topics also include the relationship between the microbiome and mental health, the implications of commonly used medications like Tylenol on gut health, and practical advice for maintaining a healthy gut during travel and holiday seasons.
In this episode of The Birth Lounge Podcast, HeHe sits down with Dr. Brian Thornburg, a board-certified pediatrician, to tackle one of the most overwhelming parts of early parenthood: newborn procedures and vaccine decisions. From the very first hours after birth, parents are presented with a whirlwind of choices—Vitamin K, Hep B, eye ointment, vaccine schedules—and it can feel impossible to sort fact from fear. Dr. Thornburg breaks down what's truly evidence-based, what questions to ask your care team, and how to advocate for your baby with confidence. Together, they explore: How your newborn's immune system really works (and mom's role in it!) The ins and outs of Vitamin K, Hep B, and erythromycin at birth How antibiotics during labor may impact your baby's gut health Alternative vaccine schedules and what research actually says Hot-button topics like vaccine shedding, autoimmunity, and long-term impacts This conversation is about informed consent—not scare tactics. You'll walk away empowered to make decisions that feel right for your family while knowing exactly how to navigate conversations with your providers. 05:09 – Meet Dr. Thornburg: advocacy in pediatrics 08:50 – Newborn immune system + maternal impact 18:49 – Vaccinations in pregnancy: risks + research gaps 34:41 – Newborn procedures explained (Vitamin K, Hep B, erythromycin) 53:11 – Antibiotics, Group B Strep, and gut health 01:00:43 – Gut microbiome, leaky gut, and autoimmunity 01:04:28 – Navigating vaccine schedules + global perspectives 01:19:15 – Making vaccine choices: categories, delays, and risks 01:28:29 – Adverse reactions, VAERS, and herd immunity 01:39:08 – Vaccine shedding + payment myths 01:44:57 – Finding a vaccine-friendly pediatrician Guest Bio: Dr. Thornburg Wellness focuses on educating families on health and wellness through the generations by the birth of their babies and raising of their children. INSTAGRAM: Connect with HeHe on IG Connect with HeHe on YouTube BIRTH EDUCATION: Join The Birth Lounge here for judgment-free childbirth education that prepares you for an informed birth and how to confidently navigate hospital policy to have a trauma-free labor experience! Download The Birth Lounge App for birth & postpartum prep delivered straight to your phone! LINKS MENTIONED: www.drthornburg.com
The Elective Rotation: A Critical Care Hospital Pharmacy Podcast
Show notes at pharmacyjoe.com/episode1065. In this episode, I’ll discuss inhaled antibiotics to prevent VAP. The post 1065: Do Inhaled Antibiotics Prevent VAP? appeared first on Pharmacy Joe.
Thank you for joining us for our 2nd Cabral HouseCall of the weekend! I'm looking forward to sharing with you some of our community's questions that have come in over the past few weeks… Dan: my daughter 11 years old now has had for some time very large dense and hard bowel movements. our family doctor had her taking miralax at smaller doses but no solutions for long term. we have tried making sure she gets enough fiber and water but do not know what is causing this or where to start. i literally have to break up her BMs to flush the toilet . thanks for your help Charlene: hello and thank you for all your help. my wife and i have been on a body transformation journey for about two years now. we have not reached our goals, our goal is overall health but are trying to build muscle and eventually lower our body fat percentages to a healthy number. we have been on a high protein diet about a gram per pound of body weight . i know this is not great for long term. how long is too long to be on this sort of diet and how should we best go about cycling our diet for best results. trying to get down to the 20 - 30 % body fat from 40 -50%. we also strength train regularly Dan: my teenage son has alot of acne. nothing seems to do any good for it and its much worse under his shirt sleeves. our doctor wanted him to take an antibiotic di something or other. we have tried a couple or topical treatments but nothing seems to work how do we get to the bottom of this? Jean: I wake up too many days now with brain fog, extreme fatigue, no energy and headaches. Different parts of my body have discomfort. Thank you for answering my question. Sheena: Hi Dr. C! Hope you and your team are well. (This is the third time I've written in regarding this question). My liquid vitamin D says 1 drop equals 1000iu. . I was wondering if I can trust that? Because it seems soo little compared to a tablet. I end up consuming more drops then I need to, just in case. Thx in advance for answering! Thank you for tuning into this weekend's Cabral HouseCalls and be sure to check back tomorrow for our Mindset & Motivation Monday show to get your week started off right! - - - Show Notes and Resources: StephenCabral.com/3523 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!
Do not get gallbladder removal surgery unless you have to! Learn more about gallbladder stones, gallbladder function, and the side effects of gallbladder removal. Find out why gallbladder removal isn't the only solution! 0:00 Introduction: Do not get your gallbladder removed!0:15 Gallbladder surgery 0:53 Gallbladder function 3:12 Gallbladder stones 3:56 Gallbladder removal lies6:25 Problems from gallbladder removal8:30 What causes gallstones?10:58 How to increase bile and prevent gallbladder stones DATA:https://lifewithnogallbladder.org/https://surgeonadamharris.com/understanding-the-long-term-side-effects-of-gallbladder-removalSupport a healthy gallbladder with Healthy Keto® and intermittent fasting. This FREE guide shows you how: https://drbrg.co/470t2J6The gallbladder is a small sac that sits below the liver with the following important functions:•Bile storage and concentration•Regulation of bile release •Cholesterol regulation•Antimicrobial functions•Hunger and blood sugar control•Detox support •Helps trigger the antioxidant glutathione Bile is vital for the breakdown of fats, so you can absorb fat-soluble vitamins A, E, D, K1, K2, and omega-3 fatty acids. Bile can also help thyroid hormones work more efficiently. Gallbladder removal surgery is often the result of gallbladder stones. Gallstones come from a lack of bile. People are often told the following lies and convinced into gallbladder removal surgery:•There are no other options.•A diseased gallbladder causes gallstones.•You can't prevent gallstones with diet.•Gallbladder removal does not cause complications.•Post-cholecystectomy is controversial.•Gallstones that result from pregnancy require gallbladder removal surgery. Gallstones can be caused by high levels of estrogen, being overweight, and diabetes, but one of the biggest gallbladder stone causes is high insulin!Insulin resistance resulting from chronically high insulin levels can prevent the liver from producing adequate bile and weaken the gallbladder. A low-carb diet and intermittent fasting are the best solutions for gallbladder stones. Your microbes also produce bile, so anything that destroys them can affect bile. Antibiotics and low-fat, low-cholesterol diets increase the risk for gallstones.Fatty fish has the most potent effect on bile production. You can also increase bile with cholesterol foods such as butter, eggs, shellfish, seafood, and liver. Egg yolks and liver are high in choline, a key nutrient vital for bile production. Bitter greens, arugula, radish, celery, and sauerkraut can help make additional bile salts.Dr. Eric Berg DC Bio:Dr. Berg, age 60, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the Director of Dr. Berg Nutritionals and author of the best-selling book The Healthy Keto Plan. He no longer practices, but focuses on health education through social media.Disclaimer: Dr. Eric Berg received his Doctor of Chiropractic degree from Palmer College of Chiropractic in 1988. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Berg is a licensed chiropractor in Virginia, California, and Louisiana, but he no longer practices chiropractic in any state and does not see patients, so he can focus on educating people as a full-time activity, yet he maintains an active license. This video is for general informational purposes only. It should not be used to self-diagnose, and it is not a substitute for a medical exam, cure, treatment, diagnosis, prescription, or recommendation. It does not create a doctor-patient relationship between Dr. Berg and you. You should not make any change in your health regimen or diet before first consulting a physician and obtaining a medical exam, diagnosis, and recommendation. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition.
Antibiotics can save lives… but they can also wipe out your gut. In this episode, I walk you through a functional medicine roadmap for recovery: the first steps to take after antibiotics, how to rebuild your microbiome with probiotics, prebiotics, and fermented foods, and the nutrients that strengthen your gut lining. You'll also learn what to do if diarrhea lingers, and how to set realistic expectations for recovery. It's common for gut healing to take six months to a year. This episode is your guide to restoring balance and resilience after antibiotics. Recovering from antibiotics supplement protocol (20% off at signup): http://healthfulpursuit.com/fullscript Hosted by Leanne Vogel. Coaching and other supports available at: https://shop.healthfulpursuit.com/ Podcast Sponsors, links and offers available at: https://www.healthfulpursuit.com/podcast/ Bioactive Peptides: https://www.healthfulpursuit.com/make
Why are we still treating acute uncomplicated diverticulitis with antibiotics? There is plenty of evidence from several randomized controlled trials demonstrating that symptomatic management alone yields similar results. If we should continue prescribing antibiotics for acute uncomplicated diverticulitis, which patients should undergo treatment and when? Join Drs. Jared Hendren, Elissa Dabaghi, Joseph Trunzo, Ajaratu Keshinro, and David Rosen as they discuss the management of uncomplicated diverticulitis while reviewing groundbreaking literature. Hosts: -Jared Hendren, MD Institution: Department of General Surgery, Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, Ohio - Elissa Dabaghi, MD Institution: Department of General Surgery, Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, Ohio - Joseph Trunzo, MD Institution: Department of Colon and Rectal Surgery, Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, Ohio Social Media Handle: X/Twitter @joseph_trunzo - Ajaratu Keshinro, MD Institution: Department of Colon and Rectal Surgery, Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, Ohio Social Media Handle: X/Twitter- @AJKesh - David Rosen, MD Institution: Department of Colon and Rectal Surgery, Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, Ohio Social Media Handle: X/Twitter- @davidrrosenmd Learning Objectives: By the end of this episode, listeners will be able to: 1. Identify criteria for managing acute uncomplicated diverticulitis without antibiotics based on recent literature 2. Define uncomplicated and complicated diverticulitis 3. Discuss nuanced management decisions of patients with uncomplicated diverticulitis to determine when antibiotics may be appropriate for management References: 1. Azhar, N., Aref, H., Brorsson, A., Lydrup, M.‑L., Jörgren, F., Schultz, J. K., & Buchwald, P. (2022). Management of acute uncomplicated diverticulitis without antibiotics: Compliance and outcomes – a retrospective cohort study. BMC Emergency Medicine, 22(1), Article 28. https://doi.org/10.1186/s12873‑022‑00584‑X 2. Mora‑López, L., Ruiz‑Edo, N., Estrada‑Ferrer, O., Piñana‑Campón, M. L., Labró‑Ciurans, M., Escuder‑Perez, J., Sales‑Mallafré, R., Rebasa‑Cladera, P., Navarro‑Soto, S., Serra‑Aracil, X., & DINAMO‑study Group. (2021). Efficacy and safety of nonantibiotic outpatient treatment in mild acute diverticulitis (DINAMO‑study): A multicentre, randomised, open‑label, noninferiority trial. Annals of Surgery, 274(5), e435–e442. https://doi.org/10.1097/SLA.0000000000005031 3. Daniels, L., Ünlü, Ç., de Korte, N., van Dieren, S., Stockmann, H. B., Vrouenraets, B. C., Consten, E. C., van der Hoeven, J. A., Eijsbouts, Q. A., Faneyte, I. F., Bemelman, W. A., Dijkgraaf, M. G., & Boermeester, M. A. (2017). Randomized clinical trial of observational versus antibiotic treatment for a first episode of CT‑proven uncomplicated acute diverticulitis. British Journal of Surgery, 104(1), 52‑61. https://doi.org/10.1002/bjs.10309 4. Chabok, A., Påhlman, L., Hjern, F., Haapaniemi, S., & Smedh, K.; AVOD Study Group. (2012). Randomized clinical trial of antibiotics in acute uncomplicated diverticulitis. British Journal of Surgery, 99(4), 532–539. https://doi.org/10.1002/bjs.8688 Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more. If you liked this episode, check out our recent episodes here: https://behindtheknife.org/listen Behind the Knife Premium: General Surgery Oral Board Review Course: https://behindtheknife.org/premium/general-surgery-oral-board-review Trauma Surgery Video Atlas: https://behindtheknife.org/premium/trauma-surgery-video-atlas Dominate Surgery: A High-Yield Guide to Your Surgery Clerkship: https://behindtheknife.org/premium/dominate-surgery-a-high-yield-guide-to-your-surgery-clerkship Dominate Surgery for APPs: A High-Yield Guide to Your Surgery Rotation: https://behindtheknife.org/premium/dominate-surgery-for-apps-a-high-yield-guide-to-your-surgery-rotation Vascular Surgery Oral Board Review Course: https://behindtheknife.org/premium/vascular-surgery-oral-board-audio-review Colorectal Surgery Oral Board Review Course: https://behindtheknife.org/premium/colorectal-surgery-oral-board-audio-review Surgical Oncology Oral Board Review Course: https://behindtheknife.org/premium/surgical-oncology-oral-board-audio-review Cardiothoracic Oral Board Review Course: https://behindtheknife.org/premium/cardiothoracic-surgery-oral-board-audio-review Download our App: Apple App Store: https://apps.apple.com/us/app/behind-the-knife/id1672420049 Android/Google Play: https://play.google.com/store/apps/details?id=com.btk.app&hl=en_US
Donate (no account necessary) | Subscribe (account required) Join Bryan Dean Wright, former CIA Operations Officer, as he dives into today's top stories shaping America and the world. In this episode of The Wright Report, we cover the shocking assassination of Charlie Kirk, Russian drones breaching NATO airspace, Trump's war on Venezuela's cartels, Mexico's tariff fight with China, a pharmaceutical victory in Tennessee, and new revelations in the 9/11 families' lawsuit against Saudi Arabia. From political violence at home to dangerous escalations abroad, today's brief carries heavy news on a day of prayer and remembrance. Charlie Kirk Assassinated in Utah: The 31-year-old Turning Point USA founder was gunned down while speaking at Utah Valley University. President Trump called him “a martyr for truth and freedom” and ordered flags at half-staff. Video shows a sniper shot to the neck from a rooftop as Kirk addressed thousands of students. MSNBC sparked outrage with coverage that suggested Kirk's “awful words” made his death inevitable. Bryan warns, “The seal has now been broken: if you make those arguments or say those words, you're fair game too.” Russian Drones Violate Polish Airspace: NATO confirms 19 Russian drones flew over 150 miles into Poland, with several shot down by Dutch and Polish jets. Bryan cautions that even an accident could spark a “Gulf of Tonkin–like incident” dragging NATO into direct war with Moscow. Trump Escalates War on Venezuela's Cartels: After U.S. forces sank a drug boat killing 11, critics accuse Trump of overstepping presidential authority. War Secretary Pete Hegseth countered: “This strike sent a clear message: If you traffic drugs toward our shores, the United States military will stop you cold.” Mexico Tariffs Chinese Imports: President Claudia Sheinbaum hikes tariffs on Chinese cars and textiles to 50 percent, aiming to shield Mexican workers and appease Trump's demands to close tariff loopholes. Bryan notes this could undercut Beijing's backdoor into U.S. markets. Saving U.S. Antibiotics in Tennessee: Trump brokers a deal forcing Walmart and McKesson to buy amoxicillin from Bristol, Tennessee, rescuing America's last antibiotic factory from collapse. “Don't bet against America,” Bryan says, “because with leadership that actually loves this country, we will win.” 9/11 Families' Lawsuit Against Saudi Arabia Advances: A New York judge allows families to pursue claims that Saudi intel officers Omar al-Bayoumi and Fahad al-Thumairy aided hijackers. ProPublica reports al-Bayoumi was a Saudi intel asset in the U.S. coordinating with the GIP. Bryan calls for Trump to declassify CIA files: “It's time for some sunlight on what did or didn't happen that horrific day.” "And you shall know the truth, and the truth shall make you free." - John 8:32 Take your personal data back with Incogni! Get 60% off an annual plan at incogni.com/TWR and use code TWR at checkout. Keywords: Charlie Kirk assassination Utah, Trump martyr for truth, MSNBC Charlie Kirk coverage, Russian drones Poland NATO, Trump Venezuela drug cartels strike, Pete Hegseth drug cartels al Qaeda, Mexico tariffs Chinese imports Sheinbaum, Trump tariff war China backdoor, U.S. antibiotics Bristol Tennessee amoxicillin, Walmart McKesson Trump drug deal, 9/11 families lawsuit Saudi Arabia, Omar al-Bayoumi Saudi intel, Fahad al-Thumairy Saudi cleric, CIA Saudi 9/11 declassification