Podcasts about molecular

Videos: 1. The great recycling LIE (what really happens to plastic) (10:44) 2. Is It Game Over? New NASA Report (5:30) 2. You won't believe what Justin Trudeau's government just did | Redacted with Clayton Morris (13:26) 3. Neil Oliver – Who pulls the strings – Pandemic Treaty, Wealth & Power? (2:00) 4. He's EXPOSING the truth in Syria and they don't like it | Redacted conversation w/ Kevork Almassian (first 10:00) 5. Russian Ruble now best performing currency in the world this year… another example of how US sanctions have failed. 6. Vanessa Beeley and Eva Bartlett are smeared by the Guardian for reporting the truth (3:07) 7. Kim Iversen: Inside The SECRET Bilderberg Meetings Between Spies, War Hawks And World Leaders (9:28) 8. New Rule: The Misinformation Age | Real Time with Bill Maher (HBO) 9. https://theduran.locals.com/post/2311112/title  10. https://www.youtube.com/watch?v=3maIN4-ZJl8    Strawberry Compound Shown to Protect Against Alzheimer's, Memory Loss Salk Institute for Biological Studies, June 16, 2022  The thought of losing your mind is a frightening one, but one in three Americans die with Alzheimer's or some other form of dementia. Regardless how frightening the possibility is, the chances of it happening to you aren't exactly slim, which means prevention should be at the forefront of your mind. A recent study from the Salk Institute for Biological Studies indicates prevention could be as simple as a natural foods diet—rich in fruits (such as strawberries) and vegetables containing something called fisetin. Fisetin is a flavonol found in strawberries, mangoes, cucumbers, and other vegetables and fruits. Researchers with the Salk Institute found this simple compound can actually reduce the risk of Alzheimer's in mice, and could be effective in humans as well. Maher and her team have documented that fisetin has both anti-inflammatory and antioxidant properties in the brain. It is also able to turn on a cellular pathway related to memory function. The team looked to a type of mouse with mutated genes making them vulnerable to Alzheimer's. At three months old, the researchers began feeding the mice a diet enriched with fisetin. Mice who hadn't received the fisetin began struggling in the mazes at nine months of age, but the fisetin mice performed as well as normal (non-predisposed) mice at both nine and twelve months of age. Avocados may hold the answer to beating leukemia University of Waterloo (Canada), June 16, 2022 Rich, creamy, nutritious and now cancer fighting. New research reveals that molecules derived from avocados could be effective in treating a form of cancer. Professor Paul Spagnuolo from the University of Waterloo has discovered a lipid in avocados that combats acute myeloid leukemia (AML) by targeting the root of the disease – leukemia stem cells. Worldwide, there are few drug treatments available to patients that target leukemia stem cells. “The stem cell is really the cell that drives the disease,” said Professor Spagnuolo, in Waterloo's School of Pharmacy. “The stem cell is largely responsible for the disease developing and it's the reason why so many patients with leukemia relapse. We've performed many rounds of testing to determine how this new drug works at a molecular level and confirmed that it targets stem cells selectively, leaving healthy cells unharmed.” Inability to stand on one leg for 10 seconds in mid to later life linked to near doubling in risk of death Exercise Medicine Clinic-CLINIMEX (Brazil) and University of Eastern Finland, June 21, 2022 The inability to stand on one leg for 10 seconds in mid- to later life is linked to a near doubling in the risk of death from any cause within the next 10 years, finds research published online in the British Journal of Sports Medicine This simple and safe balance test could be included in routine health checks for older adults, say the researchers. The researchers wanted to find out whether a balance test might be a reliable indicator of a person's risk of death from any cause within the next decade, and, as such, might therefore merit inclusion in routine health checks in later life. Participants were asked to stand on one leg for 10 seconds without any additional support.  To improve standardization of the test, participants were asked to place the front of the free foot on the back of the opposite lower leg, while keeping their arms by their sides and their gaze fixed straight ahead. Up to three attempts on either foot were permitted. In all, around 1 in 5 (20.5%; 348) participants failed to pass the test. The inability to do so rose in tandem with age, more or less doubling at subsequent 5 year intervals from the age of 51-55 onwards.  The proportions of those unable to stand on one leg for 10 seconds were: nearly 5% among 51-55 year-olds; 8% among 56-60 year-olds; just under 18% among 61-65 year-olds; and just under 37% among 66-70 year-olds.  More than half (around 54%) of those aged 71-75 were unable to complete the test. In other words, people in this age group were more than 11 times as likely to fail the test as those just 20 years younger. During an average monitoring period of 7 years, 123 (7%) people died: cancer (32%); cardiovascular disease (30%); respiratory disease (9%); and COVID-19 complications (7%). The proportion of deaths among those who failed the test was significantly higher: 17.5% vs. 4.5%, reflecting an absolute difference of just under 13%. Anxious Children have Bigger “Fear Centers” in the Brain Stanford University School of Medicine, June 16, 2022 The amygdala is a key “fear center” in the brain. Alterations in the development of the amygdala during childhood may have an important influence on the development of anxiety problems, reports a new study in the current issue of Biological Psychiatry.

 Researchers at the Stanford University School of Medicine recruited 76 children, 7 to 9 years of age, a period when anxiety-related traits and symptoms can first be reliably identified.  The researchers found that children with high levels of anxiety had enlarged amygdala volume and increased connectivity with other brain regions responsible for attention, emotion perception, and regulation, compared to children with low levels of anxiety. They also developed an equation that reliably predicted the children's anxiety level from the MRI measurements of amygdala volume and amygdala functional connectivity.

The most affected region was the basolateral portion of the amygdala, a subregion of the amygdala implicated in fear learning and the processing of emotion-related information.

 Our study represents an important step in characterizing altered brain systems and developing predictive biomarkers in the identification for young children at risk for anxiety disorders,” Qin said.  New research: Olive oil compound destroys cancer cells in 30 minutes Rutgers University & Hunter College, June 12, 2022  Oleocanthal, a polyphenolic, therapeutic compound found in olive oil is the subject of a new anti-cancer study performed by nutritional science and cancer biology researchers with The School of Environmental and Biological Sciences at Rutgers and Hunter's College in New York City. Programmed cell death, known as apoptosis takes approximately 16-24 hours. Dynamic new research just published in the Journal of Molecular and Cellular Oncology blew scientists away – when exposed to oleocanthal, a polyphenol compound found in olive oil, cancerous cells died within 30 minutes to an hour. While researchers previously understood that compounds in olive oil were capable of killing cancer cells, until now, such short apoptosis had not been observed. Even more fascinating was when the team looked closely to surmise why apoptosis was occurring under such swift circumstances – they discovered that cancer cells were being killed by their own enzymes. And, not only one isolated type of cancerous cell, but all of the cancerous cells they were examining. Unlike chemotherapeutic pharmaceuticals that devastate healthy cellular activity, the therapeutic polyphenolic compound found in olive oil kills cancer while maintaining vitality among healthy cells. As Paul Breslin, one of the study's authors at Rutgers noted, while cancerous cells died, healthy cells were not harmed, but rather the oleocanthal “put them to sleep.” The lifecycle of healthy cells was only temporarily affected in this way, without any negative observations and in approximately 24 hours, the healthy cells resumed their life cycle.  Sports, not screens: The key to happier, healthier children University of South Australia, June 21, 2022 Whether it's sports practice, music lessons or a casual catch up with friends, when children are involved in after-school activities, they're more likely to feel happier and healthier than their counterparts who are glued to a screen. In a new study conducted by the University of South Australia, researchers found that children's well-being is heightened when they participate in extra-curricular activities, yet lowered when they spent time on social media or playing video games. Published in BMC Pediatrics, the study analyzed data from 61,759 school students in years 4 to 9, assessing the average number of days per week children participated in after-school activities (3–6pm), and measure these against well-being factors—happiness, sadness, worry, engagement, perseverance, optimism, emotion regulation, and life satisfaction. It found that most students watched TV about four days of the school week and spent time on social media about three days of the week. Our study highlights how some out-of-school activities can boost children's well-being, while others—particularly screens—can chip away at their mental and physical health. “Screens are a massive distraction for children of all ages. And whether children are gaming, watching TV or on social media, there's something about all screens that's damaging to their well-being. Students in lower socio-economic backgrounds who frequently played sports were 15% more likely to be optimistic, 14% more likely to be happy and satisfied with their life, and 10% more likely to be able to regulate their emotions. Conversely, children who played video games and used social media almost always had lower levels of well-being: up to 9% less likely to be happy, up to 8% to be less optimism and 11% to be more likely to give up on things.

Professor de Farmacologia da UFRGS e Coordenador do Laboratório de Câncer e Neurobiologia do Hospital de Clínicas, Rafael Roesler Biomédica, Mestre em Biologia Celular e Molecular e aluna de Doutorado em Biologia Celular e Molecular na UFRGS, Livia Fratini Oncologista e diretor do Instituto do Câncer Infantil, André Brunetto

Let the music do the talking for this episode. FSM from Dub Phizix, Logistics, Wilkinson, S.P.Y, Wingz, Submorphics, Kimyan Law, High Contrast, Winslow, Dr Meaker, A Sides & Aletta, Molecular, Alpha Rythm, Human Nature & Natus, DJ Hazard, Nami, Subwave, MAykors, Hybert Phillips, P&B and Lens.  One Love. 

Let the music do the talking for this episode. FSM from Dub Phizix, Logistics, Wilkinson, S.P.Y, Wingz, Submorphics, Kimyan Law, High Contrast, Winslow, Dr Meaker, A Sides & Aletta, Molecular, Alpha Rythm, Human Nature & Natus, DJ Hazard, Nami, Subwave, MAykors, Hybert Phillips, P&B and Lens.  One Love. 

In the past few decades, some female Muslim academics and activists have drawn on the Qur'an to argue for what they perceive should be a part of women's rights and the equality of women. The work of various individuals and organisations is broadly referred to as Islamic feminism. For a Muslim woman facing domestic violence, spiritual abuse, and financial exploitation within the Muslim community, it is easy to see why she would turn to Islamic feminist thinkers for support. The prejudice of white secular feminists doesn't appeal to her identity. In addition, she wants to gain knowledge and connect with Allah (ﷻ), but she doesn't feel welcome in some traditional Muslim spaces. Islamic feminist thinkers purport to root their opinions in the Islamic tradition, leading some to believe their views are automatically legitimate. Additionally, the egalitarian atmosphere fostered by Islamic feminist scholarship is seen as a safe space for Muslim women. “Islamic” feminist thinkers are filling a void. Is it not the case that only a handful of people champion Muslim women's issues? So when secular, articulate Muslim academics address the misogyny amongst Muslims, some are grateful and gravitate towards them. Islamic feminist thinkers gain traction often because modern Muslim societies in the East and West are not comprehensively delivering women the Islamic rights Allah (ﷻ) decreed them to have. But how can a layperson evaluate what Islamic feminist academics are saying is theologically sound? A Muslim who has not studied quranic hermeneutics or Islamic history will not have the skills or knowledge to assess their views, so women often trust them by virtue of their assertion as being pro-women. Rather than blindly accepting their assertions, we should evaluate them objectively. Just because they are women doesn't mean we unquestioningly embrace their arguments, just as we should with men. We should pause and question our motives foraloowing Islamic feminist scholars to influence our thinking. Do we agree with them because they articulate what we want to hear? Or is it a classic case of shopping around for an opinion that agrees with our sensibilities? Moreover, it is essential to assess whether these views align with the majority of scholarly mainstream Islamic opinions. InshaAllah, in this piece, my aim is to do precisely that. With my guest, Heraa Hashmi, I will be focussing on the following contemporary academics Dr. Amina Wadud, Dr. Asma Barlas, Dr. Kecia Ali, and Dr. Aysha Hidayatullah. They do not always agree, and some are more intellectually rigorous than others, but they share the objective of creating an egalitarian Islam, attempting to pursue equality and justice for women by “reforming” Islamic law. Heraa Hashmi is best known for her project, Muslims Condemn. She is a law student based in the US with a background in Molecular, Cellular, & Developmental Biology and Linguistics. Her interests include the Islamic sciences, cognitive linguistics, and bioethics. She writes for www.traversingtradition.com https://traversingtradition.com/ --- Send in a voice message: https://anchor.fm/farhatamin/message

ASCO: You're listening to a podcast from Cancer.Net. This cancer information website is produced by the American Society of Clinical Oncology, known as ASCO, the voice of the world's oncology professionals. The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guests' statements on this podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. Cancer research discussed in this podcast is ongoing, so data described here may change as research progresses. In this podcast, members of the Cancer.Net Editorial Board discuss new research in molecular testing, also known as biomarker testing or tumor marker testing, to help guide treatment for people with early-stage non-small cell lung cancer. This podcast is led by Dr. Ryan Gentzler, Dr. Xiuning Le, Dr. Brendan Stiles, and Dr. Vamsidhar Velcheti. Dr. Gentzler is the director of the Thoracic Oncology Clinical Research Program at the University of Virginia (UVA) and chairs the UVA Cancer Center's Lung Cancer Translational Research Team.  Dr. Le is an assistant professor in the Department of Thoracic/Head and Neck Medical Oncology in the Division of Internal Medicine at The University of Texas MD Anderson Cancer Center. Dr. Stiles is chief of thoracic surgery and surgical oncology at Montefiore and Albert Einstein College of Medicine. Dr. Velcheti is the director of thoracic medical oncology at New York University Langone's Perlmutter Cancer Center. View disclosures for Dr. Gentzler, Dr. Le, Dr. Stiles, and Dr. Velcheti on Cancer.Net. Dr. Gentzler: Thank you, everyone, for joining us. We've got a great group here today, and we're really going to focus on talking about molecular testing in lung cancer. This is a very hot topic. My name is Ryan Gentzler from the University of Virginia. I'm a thoracic medical oncologist. We have Drs. Le, Stiles, and Velcheti with us today. I'd like them to go ahead and introduce themselves, starting with Dr. Le. Dr. Le: My name is Xiuning Le. I'm an assistant professor. I'm at the MD Anderson Cancer Center here in Houston, Texas. I'm also a medical oncologist. Thank you, Ryan, for inviting us today. Dr. Stiles: Hey, everybody. I'm Brendan Stiles. I'm a thoracic surgeon. I'm chief of thoracic surgery at Albert Einstein College of Medicine in Montefiore Health System here in the Bronx in New York. Dr. Gentzler: All right, thanks for joining us. And Dr. Velcheti. Dr. Velcheti: Thank you, Ryan. I'm Vamsidhar Velcheti. I'm the director of the thoracic oncology program at NYU. Dr. Gentzler: All right, great. We hear a lot of terms thrown around about molecular testing, genomic testing, biomarkers, oncogenic drivers, and I thought it would be good to just define what exactly is molecular testing, so all of our listeners are aware of what we're talking about. Dr. Le, do you want to take this question? Dr. Le: Yeah. So we have many terms, as you described. In my eyes, there are 2 sets of testing, and then some of them also classify into actionable versus not actionable. So for clinical use, we usually ask the tumor to be tested for both the mutations as well as the immune marker. Usually, the panel of mutational testing is more than a field. Usually, it's depending on the platform we're using, oftentimes in the hundreds of things. And then the immune markers, usually, we refer to PD-L1 and the tumor mutational burden. Those are the 2 commonly used markers now in the clinic. Some of those markers, especially the hundreds in gene testing, not all of them can lead to a clinical decision because we're still in the phase of understanding the interactions of different genes. However, there is a subgroup of those mutations. Nowadays, we have targeted therapy for, we call those actionable mutations. So in the clinic, we push for testing for a panel of mutations as well as immune markers, hoping to look at the tumor comprehensively so that we can recommend a good treatment regimen precise to that particular tumor, precise to that particular patient. Dr. Gentzler: Yeah. Wonderful. This has also been termed precision medicine, where we really match a therapy to a specific genomic abnormality identified on these tests and maybe, Dr. Velcheti, if you could maybe elaborate on some of the different ways that these tests are performed and how we're using these in clinic today? Dr. Velcheti: Yeah, definitely. I think our understanding of the biology of lung cancer has evolved quite dramatically over the past several years and obviously it's led to a lot of advancements in terms of treatment opportunities for patients. Broadly, the way I look at biomarkers in lung cancer or, for that matter, any cancer, it's like you have biomarkers that actually kind of give us very deep insights into the biology of the cancer and giving us insights into how aggressive somebody's cancer is. Those are called prognostic biomarkers, kind of predicting outcome. And there are predictive biomarkers where there are certain biomarkers. If you do have some of these biomarkers in the tumor, then you could potentially use certain treatments that might work better for patients who have those biomarkers. So now we have a lot of different approaches in terms of how we kind of test for these biomarkers. Especially in lung cancer, now we have a lot of new therapeutics for certain genomically categorized types of lung cancer. And the challenge now is that we have so many different mutations we absolutely need that information to decide on treatment. So how do we test that? Until a few years ago, we've been doing a single gene testing. The problem with those approaches is that we have so many different genes we need to test and we kind of do sequential gene testing, a single gene testing, we won't get all the information we need to make the right decision for our patients. So the standard approach in most oncology practices, especially larger cancer centers and academic medical centers, is do comprehensive genomic profiling, and that's being widely accepted as a standard approach right now. Dr. Gentzler: Wonderful. And this has really been something that has fallen on the laps of thoracic medical oncologists as we've treated patients with advanced stage or stage 4 disease. And this is starting to become more and more important and relevant for surgeons. And Dr. Stiles, I just wanted to bring you into the conversation and see if this is something that, prior to some of the more recent data, which we'll discuss in a minute, is this something that as a surgeon, you've kept up with and think it's important in a surgical practice? Dr. Stiles: Yeah, definitely, Ryan. And I think now is probably the most exciting time for that, right? We used to just be sort of in the prognostic side, like Vamsi said, but now we really are in the predictive side in the early-stage disease. And I think that's why everybody is so excited. But that's why there's now this pressure about the timing of biomarker testing. What do you get? Do you get a whole panel? As we'll talk about some of the trials that have made their way into earlier stage disease, but it becomes inherent upon surgeons to really think about this and understand this, from the first time that they meet the patient I think, as we increasingly get better therapies in earlier stage disease. Dr. Gentzler: So as this has moved into earlier stage disease, a lot of this has been driven by some new data from clinical trials, and Dr. Velcheti, I thought maybe you could comment on the IMpower010 trial and its relevance and why molecular testing is important in the context of that trial. Dr. Velcheti: Yes, absolutely. I think the IMpower010 Trial is certainly a new shift in our approach to treating stage I, II curable non-small cell lung cancers. So we haven't had an approval in the adjuvant setting in a while. I mean, of course, we had approval with the osimertinib result of the ADAURA trial, but that's only for EGFR patients. Now we have approval for using immunotherapy in the postoperative adjuvant setting for patients with any level of PD-L1 expression. So this is a large randomized study looking at the role of adjuvant atezolizumab, which is a PD-L1 inhibitor in patients who have PD-L1 expression greater than 1%. Patients were randomized getting platinum doublet alone, which is a standard-of-care adjuvant assistant therapy for patients at stage I, II lung cancer. It is atezolizumab at a dose of 1,200 milligrams given every 3 weeks. Patients who received atezolizumab had significantly improved outcomes in disease-free survival. And the benefit was actually really striking for patients who had high PD-L1, patients with PD-L1 testing TPS score of greater than 50%. They had a really remarkable increase in terms of disease-free survival for those patients. So this is certainly very encouraging. And of course, we know it's now approved. We are still awaiting some overall survival results to mature. But given the extent of the benefits we're seeing with the disease-free survival, I think it's a very promising approach. Dr. Gentzler: Yeah, so obviously, immune therapy has had a tremendous benefit in the adjuvant setting from this trial and still some longer-term follow-up that's needed. But I think the important point here is that molecular testing may identify certain mutations that may make patients less likely to benefit or respond, or perhaps there's more appropriate treatments than immunotherapy within this group. And that brings us to the next trial that I think really shifted this discussion stage with the ADAURA trial. Maybe Dr. Le, if you could summarize this trial and give us your thoughts on why molecular testing is so important in the era of ADAURA. Dr. Le: Yeah. So ADAURA trial is also an adjuvant trial, meaning that the patient received additional treatment after the completion of surgery. So ADAURA trial looked at patients who have EGFR mutations. So it's a different biomarker. It's a gene biomarker, not the immune biomarker. So this is a large international trial, enrolled almost 700 patients and then randomized the patients after surgery, after standard chemo, the patient can go on to either receive 3 years of osimertinib, which is the standard-of-care therapy for EGFR mutant patients for metastatic setting, or the control group if the patient just received standard of care, which is to continue the monitoring. The trial actually showed that for people who had osimertinib before that prolonged time of 3 years, the risk of the disease coming back is almost 5 times lower than the patient who did not receive therapy. So based on that really striking benefit of after surgery, after chemotherapy, continue osimertinib in EGFR patients, FDA approved after the surgical resection and all the standard care patient can go on for osimertinib for a prolonged time, which we think currently the data is saying the disease is more likely not to come back. And hopefully, in the future, that result will translate into overall survival benefit. Dr. Gentzler: Okay, wonderful. And I think both of these trials, both the ADAURA and the IMpower010, are adjuvant trials. So these are trials that allow us adequate time to do molecular testing on a large surgical specimen, formulate our plans, and implement those plans up to a month or longer after surgery. Obviously, there's some new data that we've seen in a press release from the CheckMate 816 trial. This is a neoadjuvant trial of chemotherapy plus nivolumab. We've seen previous data from this trial showing some results, but this moves the conversation into the neoadjuvant space, and Dr. Stiles, I wonder if you could give us a summary of your thoughts on the CheckMate 816 and the relevance for molecular testing in that context of neoadjuvant therapy. Dr. Stiles: Yeah. Thanks, Ryan. I think, first of all, those are incredibly important adjuvant trials. I saw 2 patients each this week on adjuvant osimertinib and adjuvant atezo [atezolizumab], so it's real-life practice. Every day, it's going to benefit patients. But I think that's easy, like you said, these are big specimens that are taken out. You've got time to decide while the patient gets better. Now, we have to shift all this even earlier because CheckMate 816 really has some pretty impressive results. We, unfortunately, don't have the paper yet. I'm told it's going to be coming out soon, but the primary endpoint pathologic complete response 24% versus 2.2%. That's with chemo-nivo versus chemo alone. Obviously, people are questioning, does pathologic complete response correlate with outcomes? Certainly, we got a signal on a press release that the event-free survival is going to be the hazard ratio is 0.63, so it sounds like it does, and I think we'll see more data on that in the next couple of months. A difference in median event-free survival of 32 months versus 21 months in the report. So everybody is excited to see this. And I think it has some advantages over the adjuvant strategy. First of all, more patients are able to tolerate it. It's just 3 cycles, and so it's not given indeterminately for a year. And it worked across different subgroups. And we can talk about some of the nuances, but as where atezo [atezolizumab] was only looking good in the PD-L1-high. This sort of worked across different groups. The caveat to that is we don't really know what happens with these EGFR patients who are eligible and sort of, how do we then move that test? And all of a sudden, we've got to make a decision on neoadjuvant therapy. Now we need to know. It helps to know the PD-L1 maybe preoperatively, with the high PD-L1, maybe you could wait until adjuvant therapy, with the low to sort of medium PD-L1, maybe you want to give them their shot in the neoadjuvant space. But if they have an EGFR mutation, it's probably not the right thing. We don't really know the data on that and CheckMate 816 yet, but certainly, I'd be sort of hesitant to give them neoadjuvant chemoimmunotherapy. So then you have to teach surgeons all this too, and teach them to think about this and teach them to hold their horses on taking patients to the operating room while they wait for molecular testing. But that probably means we need to speed up the process somewhat either with sort of more rapid turnaround test, with consideration of liquid tests in some instances. It's just an incredibly fast-changing place that here we are speaking about a trial that hasn't even been published yet, so that tells you how fast things are happening. Dr. Gentzler: One last question. How can the results of these tests guide therapy after surgery? Do we incorporate a full NGS [next-generation sequencing] panel at the time of surgery? And we don't have data on adjuvant therapy for ALK or ROS1, or RET. Do we factor that into how we think about adjuvant chemotherapy, adjuvant immunotherapy, do we employ targeted therapies for some of these mutations? Any thoughts on that? Dr. Le: Ryan, I think you bring an important point in that EGFR is 1 of the 8 actionable mutations we have nowadays based on FDA and NCCN. The tumor biology between EGFR and ALK-fusion oncogenesis and potential response and benefits probably share some similarities. So we look forward to seeing trials reporting out the adjuvant setting with ALK inhibitors with ROS1. And the smaller target might require a multi-institutional or co-op group effort to really achieve the sample size for us to see. But as of now, we don't have the approval. We try to enroll patients to the oncogene trials, but I think currently we're practicing based on EGFR and PD-L1. Dr. Stiles: Yes, and I agree. I'm excited to see what comes out of some of those trials. They're slow to grow, but we'll eventually get some readouts. I think an interesting question sometimes is PD-L1. And we had an example recently where in the pre-op biopsy, the patient had a low PD-L1, and so not particularly enthusiastic. And the question sometimes arises, do you test that whole tumor to consider them as kind of an adjuvant to atezo [atezolizumab]and then the fully resected tumor, the PD-L1 was greater than 50%. And so I would sort of sound a caution that the small biopsy sample, they're incredibly helpful for many things, incredibly helpful for moleculars. It may not always be totally representative of the PD-L1 staining. Dr. Gentzler: And I think that's a good point. Even for molecular testing, sometimes if you have smaller biopsies, you may get a result that's negative, but it could be low levels of DNA and not sufficient to complete the full panel with high quality. So you really have to pay attention to the report and make sure that there's some confidence in the amount of DNA in some of these results. Well, I think that's all the time we have here, so I appreciate everyone's participation, and hopefully we're able to learn a little bit about genomic testing today. ASCO: Thank you, Dr. Gentzler, Dr. Le, Dr. Stiles, and Dr. Velcheti. Learn more about treating lung cancer at www.cancer.net/lung.  Cancer.Net Podcasts feature trusted, timely, and compassionate information for people with cancer, survivors, and their families and loved ones. Subscribe wherever you listen to podcasts for expert information and tips on coping with cancer, recaps of the latest research advances, and thoughtful discussions on cancer care. And check out other ASCO Podcasts to hear the latest interviews and insights from thought leaders, innovators, experts, and pioneers in oncology. Cancer.Net is supported by Conquer Cancer, the ASCO Foundation, which funds lifesaving research for every type of cancer, helping people with cancer everywhere. To help fund Cancer.Net and programs like it, donate at CONQUER.ORG/Donate.

Ryan was the attorney for Vitamin Water in its early days and was with the company all the way through it's sale to Coke for over $4 billion. We talk about the VitaminWater story along with others he's worked with in the CPG industry. Ryan's firms has worked with hundreds of other consumer product companies including Glaceau (creator of VitaminWater and SmartWater), Pirate's Booty, Pretzel Crisps, Vita Coco, Siggi's, WTRMLN WTR, Mamma Chia, Sir Kensington's, Hint, Califia Farms, Krave, HappyBaby, Chameleon Cold Brew, Essentia, Rhythm Superfoods, Peeled, Runa, Oatmega, Sugarfina, Juice Press and many more.  About Ryan Lewendon Ryan is a Partner at Giannuzzi Lewendon, a premier boutique law firm that focuses on the representation of privately-held, high-growth consumer products companies. Prior to joining Giannuzzi Lewendon in 2011, Ryan was an associate at Donovan & Giannuzzi LLP. Since 2007, Ryan has focused his practice on helping innovative consumer products entrepreneurs grow their companies by navigating both the day-to-day hurdles and the tent-pole obstacles and opportunities a consumer products company must navigate on its way towards an acquisition. Ryan has assisted hundreds of companies structure and negotiate their distributor, broker and supplier relationships, employee incentive programs and advisory networks, and celebrity/influencer endorsements and promotional partnerships. Ryan has advised clients through financing transactions at every stage of their growth cycle – from angel investments to rounds with institutional investors. He has recently assisted clients in exit transactions with acquirers such as Coke, Pepsi, General Mills, Boulder Brands, Group Danone, Bacardi, General Mills and others. Ryan grew up in Hamden, Connecticut. He received a M.S in Molecular and Cellular Biology from Tulane University and a J.D. from Brooklyn Law School, where he was a member of the Moot Court Honors Society's Sports Law team. When he isn't busy helping bring emerging brands to the mainstream, he is an avid runner, reader and raconteur. He resides in Manhattan, New York. Join over 17,000 others and sign up to receive bonus content with the EDGE's weekly newsletter.   It's free sign up here >>> EPISODE LINKS: Giannuzzi Lewendon PODCAST INFO: Apple Podcasts: EDGE on Apple Podcasts Spotify: EDGE on Spotify  RSS Feed: EDGE's RSS Feed Website: EDGE Podcast SUPPORT & CONNECT EDGE's Weekly NewsletterJoin over 17,000 others and sign up to receive bonus content. It's free sign up here >>> Please Support this Podcast by checking out our Sponsors: Mad River Botanicals 100% certified organic CBD products. The product is controlled from seed to end product by it's owners. Use code: EDGE22 to get 10% off all your orders. Shop here>>> A top podcast for entrepreneurs!

El monitoreo sanitario en la etapa de engorde puede ser muy desafiante en muchas ocasiones. El período en que los cerdos transitan ésta etapa es muy largo, y la pérdida económica puede ser mucha si no detectamos los problemas y actuamos a tiempo. La estrategia de monitoreo debe recolectar la mayor cantidad de información posible, y esa información debe ser correctamente analizada. Javier Sarradell nos cuenta desde su experiencia, cómo podemos hacer un correcto monitoreo de enfermedades en nuestros galpones de engorde y analizar la producción de una granja. Lo que vas a aprender: - Importancia del control sanitario en sitio 3 o engorde. - ¿Cómo armar el plan de monitoreo para obtener los datos sanitarios más importantes en el engorde? - ¿Cómo evaluar el retorno a la inversión (ROI) de la implementación de las vacunas? - Cómo desafiar el sistema al momento de evaluar la eficacia vacunal o hacer intervenciones de manejo o medicamentosas. Nuestro invitado: Javier Sarradell, es Médico Veterinario, egresado de la Universidad Nacional de Rosario en Argentina. Realizó su Doctorado en la Facultad de Veterinaria de la Universidad de Las Palmas de Gran Canaria, España, cuyo trabajo de tesis estuvo vinculado a la respuesta inmune relacionada con la infección por Mycoplasma hyopneumoniae en el pulmón de los porcinos. Trabajó durante un año con los patólogos del Grupo Porcino (“Swine Group”) de la Universidad de Minnesota. En la actualidad es Profesor Asociado de la Cátedra de Patología General y Especial Veterinarias de la Facultad de Ciencias Veterinarias - Universidad Nacional de Rosario. Allí, también desempeña tareas como Director de los Servicios de Diagnóstico Anátomo-Histopatológico de Especies Domésticas y de Asesoramiento Sanitario en Porcinos y de Biología Molecular. Actualmente también se desempeña como consultor independiente de empresas, dedicado al asesoramiento sanitario de granjas porcinas.

Andrei Iagaru director Stanford on Bombesin and more We chat with Andrei Iagaru about the complimentary radiotracer and theragnostic tracer bombesin. https://www.nuccast.com  Nuccast.com... This podcast is for nuclear medicine professionals and PET professionals This is one of the worlds longest running medical podcasts. Direct link to itunes itunes link Please email suggestions for topics, offers of interviews, bouquets and brickbats. nucmedpodcast@gmail.com

Carles Mesa charla "Mano a mano" con la periodista María Ramírez, autora del libro El periódico. 25 años de auge y catarsis del periodismo en internet (Ed. Debate).Y en el Podio de Olga Viza abrimos un nuevo capítulo de ciencia aplicada al deporte con el catedrático de Bioquímica y Biología Molecular de la Universidad de Murcia (UMU) José manuel López Nicolás. Escuchar audio

En "El Podio" de Olga Viza abrimos un nuevo capítulo de ciencia aplicada al deporte con el catedrático de Bioquímica y Biología Molecular de la Universidad de Murcia (UMU) José Manuel López Nicolás. Escuchar audio

You asked - we answer! For this Q&A episode we collected questions from our social media (links below) and cover these questions in detail: 01:06 What is molecular mimicry? 19:05 What type of exercise should you be doing while on a gut protocol or when experiencing gut issues? 46:41 What causes sugar cravings? Don't forget to check out the Instagram live we recorded as a continuation of this episode -> profiles are linked below! Our aim with this podcast is to educate you and provide you with tools to optimise your life by healing your gut. If you enjoyed todays episode, please share it with someone you think will benefit from it! Connect with us online, we'd love to hear from you on IG! Dave IG: https://my.captivate.fm/dashboard/podcast/7f4f56bb-c870-4c82-925a-3c9e916797ba/www.instagram.com/dave.o.brien/ (www.instagram.com/dave.o.brien/) Website: http://daveobrien.com.au/ (http://daveobrien.com.au) Jake IG: https://my.captivate.fm/dashboard/podcast/7f4f56bb-c870-4c82-925a-3c9e916797ba/www.instagram.com/coach_jakedoleschal/ (www.instagram.com/coach_jakedoleschal/) Website: https://my.captivate.fm/dashboard/podcast/7f4f56bb-c870-4c82-925a-3c9e916797ba/www.coachjakedoleschal.com (www.coachjakedoleschal.com) We'd be so thankful for a review on Apple Podcasts. Please let us know on Instagram which topic you'd like us to cover next. We look forward to hearing from you. None of the information provided in A Gut Feeling is intended to treat, diagnose, or give medical advice. Please consult a healthcare professional before making any changes to your lifestyle.

Nos pasamos la vida comiendo sin saber lo que engullimos, o al menos, a la mayoría nos pasa eso. Por otro lado, si decidimos bucear en las oscuras aguas de la nutrición y la seguridad alimentaria, nos encontraremos que, como amateurs que somos, habrá toneladas de paja por cada aguja de valor. Para comprender un poco mejor cómo funciona este mundo y el verdadero uso de los alimentos funcionales, hemos traído a José Manuel López Nicolás. López Nicolás, Licenciado en Ciencias Químicas y Premio Extraordinario de Doctorado. Actualmente es Catedrático de Bioquímica y Biología Molecular en el Departamento de Bioquímica y Biología Molecular-A de la Universidad de Murcia. Forma parte del Grupo de Excelencia Investigadora “Bioquímica y Biotecnología enzimática”. Imparte clases en los grados de Biotecnología, Bioquímica y Ciencia y Tecnología de los Alimentos y es profesor en el Máster de Biología Molecular y Biotecnología. Finalmente, ha realizado una intensa actividad de transferencia del conocimiento tanto a nivel industrial como a nivel de comunicación científica a la sociedad. Es autor de 4 libros de divulgación científica, siendo el último: La ciencia de los campeones.

Buy/Stream: https://overview.fanlink.to/OVR055-Waeys Everyone's favourite moustached producer and 2020 Best Newcomer winner Waeys returns to Overview for his first full release on the label since the immense 'Objection EP' The Dutch artist is not holding back, with a straight up club orientated 4 tracker in the form of 'The Rush EP' which also features big collaborations from fellow vibe makers Molecular & Levela. This is Waeys at his best, back on the label that helped start his journey to the top with a bang. Honks ahoy... Waeys https://www.facebook.com/waeyss https://soundcloud.com/waeys Overview Music https://overviewmusic.co.uk https://patreon.com/overview https://facebook.com/overviewuk https://instagram.com/overviewuk https://twitter.com/overviewuk https://soundcloud.com/overviewuk

My name is Harvey, and I am a rising junior at the University of Arizona. I am majoring in Molecular and Cellular Biology, and looking to add a minor in both Biochemistry and Fine Arts. I have been working in Dr. Lisa Nagy’s lab for almost a year and a half studying beetle segmentation regulation in Tribolium castaneum. Drosophila melanogaster has long been used as a model species, but segments differently from most other arthropods. By studying Tribolium castaneum, we will gain novel insight into how most arthropods are designed. In my spare time I enjoy hiking in the desert, creating art, and being on the UA Roller Derby team.

Welcome to episode three of a miniseries focusing on the zooarchaeology of various world regions. This episode is centered around American zooarchaeology, focusing on the natural history and anatomy of the most prominent wild and domesticated species found throughout North and South America. Tune in for beaver-pretenders, bison-cattle hybrids and even more moose/elk arguments! Interested in learning about how to use X-Rays and similar technology in archaeology? Check out the linked PaleoImaging course from James Elliot! Connect with James on Twitter: @paleoimaging Interested in sponsoring this show or podcast ads for your business? Zencastr makes it really easy! Click this message for more info. Start your own podcast with Zencastr and get 30% off your first three months with code ANIMALS. Click this message for more information. For rough transcripts of this episode go to https://www.archpodnet.com/animals/47 Links Anning, C. (2011) Inca success in Peruvian Andes 'thanks to llama dung'. BBC News. Crader, D. C. (1997). Prehistoric use of beaver in coastal Maine (USA). Anthropozoologica, 25(26), 225-236. - Halbert, N. et al. (2007). "Where the buffalo roam: The role of history and genetics in the conservation of bison on U.S. federal lands". Park Science. 24 (2): 22–29. Hirst, K.K. (2018) Llamas and Alpacas: The Domestication History of Camelids in South America. ThoughtCo. Hubbard, T. (2014). Buffalo Genocide in Nineteenth-Century North America. Colonial genocide in indigenous North America, 292-305. Petrigh, R. S., & Fugassa, M. H. (2013). Molecular identification of a Fuegian dog belonging to the Fagnano Regional Museum ethnographic collection, Tierra del Fuego. Quaternary International, 317, 14-18. Miller, G. R. (2003). Food for the dead, tools for the afterlife: Zooarchaeology at Machu Picchu. In Burger, R. L., and Salazar, L. C. (eds.), The 1912 Yale Peruvian Scientific Expedition Collections from Machu Picchu: Human and Animal Remains. Saunders, N. J. (1994). Predators of Culture: Jaguar Symbolism and Mesoamerican Elites. World Archaeology, 26(1), 104–117. Speller, C. F. et al. (2010). "Ancient mitochondrial DNA analysis reveals complexity of indigenous North American Canham domestication". Proceedings of the National Academy of Sciences. 107 (7): 2807–2812. Turner, B. L., and Armelagos, G. J. (2012). "Diet, residential origin, and pathology at Machu Picchu, Peru". American Journal of Physical Anthropology. 149 (1): 71–83. https://historicjamestowne.org/collections/artifacts/faunal-material/ https://blog.nature.org/science/2017/11/20/tracing-the-wild-origins-of-the-domestic-turkey/ Contact Alex FitzpatrickTwitter: @archaeologyfitz Simona FalangaTwitter: @CrazyBoneLady Alex's Blog: Animal Archaeology Music "Coconut - (dyalla remix)" https://www.youtube.com/watch?v=_2UiKoouqaY Affiliates Wildnote TeePublic Timeular Motion

Welcome to episode three of a miniseries focusing on the zooarchaeology of various world regions. This episode is centered around American zooarchaeology, focusing on the natural history and anatomy of the most prominent wild and domesticated species found throughout North and South America. Tune in for beaver-pretenders, bison-cattle hybrids and even more moose/elk arguments! Interested in learning about how to use X-Rays and similar technology in archaeology? Check out the linked PaleoImaging course from James Elliot! Connect with James on Twitter: @paleoimaging Interested in sponsoring this show or podcast ads for your business? Zencastr makes it really easy! Click this message for more info. Start your own podcast with Zencastr and get 30% off your first three months with code ANIMALS. Click this message for more information. For rough transcripts of this episode go to https://www.archpodnet.com/animals/47 Links Anning, C. (2011) Inca success in Peruvian Andes 'thanks to llama dung'. BBC News. Crader, D. C. (1997). Prehistoric use of beaver in coastal Maine (USA). Anthropozoologica, 25(26), 225-236. - Halbert, N. et al. (2007). "Where the buffalo roam: The role of history and genetics in the conservation of bison on U.S. federal lands". Park Science. 24 (2): 22–29. Hirst, K.K. (2018) Llamas and Alpacas: The Domestication History of Camelids in South America. ThoughtCo. Hubbard, T. (2014). Buffalo Genocide in Nineteenth-Century North America. Colonial genocide in indigenous North America, 292-305. Petrigh, R. S., & Fugassa, M. H. (2013). Molecular identification of a Fuegian dog belonging to the Fagnano Regional Museum ethnographic collection, Tierra del Fuego. Quaternary International, 317, 14-18. Miller, G. R. (2003). Food for the dead, tools for the afterlife: Zooarchaeology at Machu Picchu. In Burger, R. L., and Salazar, L. C. (eds.), The 1912 Yale Peruvian Scientific Expedition Collections from Machu Picchu: Human and Animal Remains. Saunders, N. J. (1994). Predators of Culture: Jaguar Symbolism and Mesoamerican Elites. World Archaeology, 26(1), 104–117. Speller, C. F. et al. (2010). "Ancient mitochondrial DNA analysis reveals complexity of indigenous North American Canham domestication". Proceedings of the National Academy of Sciences. 107 (7): 2807–2812. Turner, B. L., and Armelagos, G. J. (2012). "Diet, residential origin, and pathology at Machu Picchu, Peru". American Journal of Physical Anthropology. 149 (1): 71–83. https://historicjamestowne.org/collections/artifacts/faunal-material/ https://blog.nature.org/science/2017/11/20/tracing-the-wild-origins-of-the-domestic-turkey/ Contact Alex FitzpatrickTwitter: @archaeologyfitz Simona FalangaTwitter: @CrazyBoneLady Alex's Blog: Animal Archaeology Music "Coconut - (dyalla remix)" https://www.youtube.com/watch?v=_2UiKoouqaY Affiliates Wildnote TeePublic Timeular Motion

“Everyone just kind of accepts it like, ‘Yeah, I'm that way too. I can't relax on the weekends, I can't wind down. I can't let it go.' There's a cultural bravado behind that. I want to call bull on that.“ - Jill Farmer, Master Certified Coach & Lead Coach at DocWorking     When you're at work, you are in petal to the metal mode, and to be good at what you do, you need to be able to perform? Do you ever find it hard to turn off the intensity outside of work? In this episode, Lead DocWorking Master Certified Coach Jill Farmer and Jen Barna MD have a conversation about how to be mindful of where to apply the intensity within our lives. An intense physician mindset does not always yield successful results outside of work, and it's important to give yourself that restorative space to change gears and reset. As the Lead Coach of DocWorking, she examines how a strategy of unrelenting “petal to the metal” may be hindering you from achieving what you really value in your life.   Jen Barna MD is founder and CEO of DocWorking, a company that helps physicians and other healthcare professionals maximize meaning and purpose in life both in and outside of work, by combining expert coaching, peer support communities, and highly interactive courses that have maximum impact using minimal time. DocWorking also provides a concierge onboarding service for physicians and their significant others, to support them in making strong connections when relocating to a new community. Dr. Barna is the co-host of DocWorking: The Whole Physician Podcast, ranked as a top physician podcast. She is a board certified practicing radiologist, working in New York, and earned her MD and completed her Diagnostic Radiology residency at the University of Tennessee School of Medicine, a masters degree in Molecular and Cellular Biology from Washington University in St. Louis, and her undergraduate degree from Stony Brook University in New York. She is the mom of two successful young adults, both born while she was a medical student. She started DocWorking to help physicians stay in the driver's seat of their own lives.    Jill Farmer is the Lead Coach at DocWorking, a company focused on helping physicians and other healthcare professionals thrive. Jill's expertise has been featured everywhere from The Washington Post to Inc. Magazine. She travels the U.S. delivering keynotes and teaching her acclaimed programs at top healthcare organizations. Jill is the co-host of the top-rated podcast DocWorking: The Whole Physician Podcast with over 20,000 physician listeners. She was an Emmy Award winning TV journalist who is now a master certified time and stress management coach specializing in supporting physicians since 2010.  Jill Farmer is also the author of “There's Not Enough Time… and Other Lies We Tell Ourselves,” a time management bestseller and a favorite of many in medicine.    Find full transcripts of DocWorking: The Whole Physician Podcast episodes on the DocWorking Blog  The past few weeks have been busy at DocWorking! We have been working behind the scenes to add more CME credits to the THRIVE memberships. Let your CME budget help you prioritize your own wellness so you can get on with living your best life on your own terms, as defined by you, with DocWorking THRIVE.   You can take the first step today by taking our 2 Minute Balance to Burnout Quiz! Where are you on the Balance to Burnout Continuum? Take the quiz and find out today!   DocWorking empowers physicians and entire health care teams to get on the path to achieving their dreams, both in and outside of work, with programs designed to help you maximize life with minimal time.   Are you a physician who would like to tell your story? Please email Amanda Taran, our producer, at podcast@docworking.com to be considered.   And if you like our podcast and would like to subscribe and leave us a 5 star review, we would be extremely grateful!   We're everywhere you like to get your podcasts! Apple iTunes, Spotify, iHeart Radio, Google, Pandora, Stitcher, PlayerFM, ListenNotes, Amazon, YouTube, Podbean   You can also find us on Instagram, Facebook, LinkedIn and Twitter.    Some links in our blogs and show notes are affiliate links, and purchases made via those links may result in payments to DocWorking. These help toward our production costs. Thank you for supporting DocWorking: The Whole Physician Podcast!   Occasionally, we discuss financial and legal topics. We are not financial or legal professionals. Please consult a licensed professional for financial or legal advice regarding your specific situation.   Podcast produced by: Mara Heppard

This week we're diving into Facioscapulohumeral Muscular Dystrophy (FSHD) and highlighting the utilization of whole genome mapping in the diagnosis of FSHD. Joining us to explore these topics are June Kinoshita, Director of Research and Patient Engagement at the FSHD Society, and Rojan Kavosh, a genetic counselor by training who is currently a Genomic Testing Consultant at PerkinElmer Genomics.June Kinoshita joined the FSHD Society in 2012 and served as its Executive Director until September of 2017. Previously, June co-founded and served as Executive Editor of the Alzheimer Research Forum, the pre-eminent Web community for researchers in neurodegenerative disorders. June has worked closely with a variety of foundations to develop initiatives for multiple sclerosis, schizophrenia, amyotrophic lateral sclerosis, Parkinson's disease, and other disorders. She is also an entrepreneur, having co-founded N-of-One, Inc., a pioneering individualized clinical decision support oncology company. June graduated from Harvard College where she studied physics, and began her career as a science journalist, working as a writer and editor for Scientific American, Science, The New York Times Magazine, and many other national publications. Rojan Kavosh MS, CGC, is a licensed certified genetic counselor and Genomic Testing Consultant at PerkinElmer Genomics. Prior to joining PerkinElmer Genomics, she worked as a perinatal genetic counselor in the Fetal Center at Stanford Children's Hospital. Rojan graduated from UCLA with a degree in Molecular, Cell and Developmental Biology, and earned her Master's in Genetic Counseling from UC Irvine.On This Episode We Discuss:Facioscapulohumeral Muscular Dystrophy (FSHD)Types of FSHDCauses of FSHD Digenic inheritance patterns Genome optical mapping vs. whole genome sequencingThe genetic etiology of FSHD type 1 vs 2Benefits of ordering FSHD testing through PerkinElmer GenomicsClinical trials for FSHDWhen the FSHD Society predicts that treatments will be available for people with FSHDTo learn more about genetic testing for FSHD, visit PerkinElmer Genetics and the FSHD Society and be sure to follow the FSHD Society on Twitter, Facebook, LinkedIn, and Instagram. Stay tuned for the next new episode of DNA Today on June 10, 2022. New episodes are released on Fridays. In the meantime, you can binge over 185 other episodes on Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “DNA Today”. Episodes since 2021 are also recorded with video which you can watch on our YouTube channel. DNA Today is hosted and produced by Kira Dineen. Our social media lead is Corinne Merlino. Our video lead is Amanda Andreoli. See what else we are up to on Twitter, Instagram, Facebook, YouTube and our website, DNApodcast.com. Questions/inquiries can be sent to info@DNApodcast.com. HemoShear Therapeutics is a clinical stage company developing new treatments for patients with rare metabolic disorders. By partnering with fellow biopharma companies, HemoShear is accelerating their drug discovery and development programs in metabolic disorders, and also liver diseases and gout. HemoShear is currently conducting a clinical trial for a new therapy for propionic and methylmalonic Acidemia. Learn more about these conditions and the clinical trial in an upcoming episode of DNA Today! You can also visit hemoshear.com. (SPONSORED)

01. Aktive - Tell Me (Extended Mix) [Device] 02. Something Something, Tanyel - Second Sight 03. Fabric8 - Free Fall (Final Master)(Formation Dub) 04. Neonlight - Freedom 05. Artino, Chrissie Huntley - Insight 06. Neonlight, Holly Day - Corset 07. Mollie Collins, Marianna Ray, Shadow Sect, Dropset - Another Day 08. Neonlight - Bullhead 09. Freqax - Do That 10. Chaser & Malstrom - Faint 11. Neonlight - Vanity Fair 12. Skantia - Chatterbox 13. Fatloaf & Subminderz & Malstrom - Free Guy [Neuropunk Records] 14. Humanon feat. Diffe - Design (Bad Taste) 15. Neonlight - Tragedian 16. Slaine- Dogtooth (Dirtbox Dub) 17. Double Medley - Old Good Times(Paperfunk) 18. Dj Hidden - Evah Green (Pythius & Redpill Remix) 19. Skantia - Axis 20. Kleu - One Night Only (Serks Remix) 21. Dj Fresh, Vegas - Exorcist (Breakbeat Kaos) 22. Slaine- Bhx (Dirtbox Dub) 23. Filip Motovunski - Blood Overflow (Bad Taste) 24. Skantia, Nectax - Providence 25. Dopplershift Stokka - Motion Focus (feat. Leo Wood) 26. Slaine - Tremors (Dirtbox Dub) 27. Document One, Duskee - Technology 28. Fd - Shawn Kemp 29. Phonograph - Niceness (Hyperactivity Dub) 30. Command Strange Alibi - Welcome To The Future 31. Slaine- Killa Sound (Dirtbox Dub) 32. Art Twisted - Simulation Of Life 33. Mughte - Feeling You 34. Skantia - What Did You Think 35. Mughte - Whaaat(South Yard Dub) 36. Molecular, Arkaik - Break The Habit 37. Manifest - A No Way Out [Deception Dub] 38. Arxiva - Session 39. Arxiva - Cease 40. Dunk - Colossus 41. Beddy - 3Am 42. Arxiva - Samekh 43. M:Pathy - Vacillate 44. Høst - Say You Love Me 45. Gravit-E/Jay - Mirror Man 46. Jappa & Lupo - Darkest Night 47. Leks - Booty So Big 48. Midst - Ill Get You 49. Bennie, Ozone - Throw Down 50. Dunk, Dread Mc - Killa Dub 51. Classifyed - Little Something Like This 52. Mitekiss - Fromu (Hospital) 53. Derrick & Tonika - Space Diver 54. Høst - Nightlife (feat. Taurri) 55. Bru-C - Playground 56. Viewer - How It Feels 57. Mosaic-Jigsaw 58. Mosaic-Jigsaw 59. A-Audio - Who Are Ya Bros 60. Finnadrift - Sipping Away 61. Alpha Rhythm, Rezilient, Leo Wood - One Day At A Time 62. Msdos - Madness (Mathematica) 63. Dj Marky, Javeon - All 4 U 64. Alexvnder - Repose (Alpha Rhythm Remix) 65. Nelver Nic Zigzag - Ember Lights 66. Foor, Ellie Evans - See You In June (Clsm Remix)

01. Aktive - Tell Me (Extended Mix) [Device] 02. Something Something, Tanyel - Second Sight 03. Fabric8 - Free Fall (Final Master)(Formation Dub) 04. Neonlight - Freedom 05. Artino, Chrissie Huntley - Insight 06. Neonlight, Holly Day - Corset 07. Mollie Collins, Marianna Ray, Shadow Sect, Dropset - Another Day 08. Neonlight - Bullhead 09. Freqax - Do That 10. Chaser & Malstrom - Faint 11. Neonlight - Vanity Fair 12. Skantia - Chatterbox 13. Fatloaf & Subminderz & Malstrom - Free Guy [Neuropunk Records] 14. Humanon feat. Diffe - Design (Bad Taste) 15. Neonlight - Tragedian 16. Slaine- Dogtooth (Dirtbox Dub) 17. Double Medley - Old Good Times(Paperfunk) 18. Dj Hidden - Evah Green (Pythius & Redpill Remix) 19. Skantia - Axis 20. Kleu - One Night Only (Serks Remix) 21. Dj Fresh, Vegas - Exorcist (Breakbeat Kaos) 22. Slaine- Bhx (Dirtbox Dub) 23. Filip Motovunski - Blood Overflow (Bad Taste) 24. Skantia, Nectax - Providence 25. Dopplershift Stokka - Motion Focus (feat. Leo Wood) 26. Slaine - Tremors (Dirtbox Dub) 27. Document One, Duskee - Technology 28. Fd - Shawn Kemp 29. Phonograph - Niceness (Hyperactivity Dub) 30. Command Strange Alibi - Welcome To The Future 31. Slaine- Killa Sound (Dirtbox Dub) 32. Art Twisted - Simulation Of Life 33. Mughte - Feeling You 34. Skantia - What Did You Think 35. Mughte - Whaaat(South Yard Dub) 36. Molecular, Arkaik - Break The Habit 37. Manifest - A No Way Out [Deception Dub] 38. Arxiva - Session 39. Arxiva - Cease 40. Dunk - Colossus 41. Beddy - 3Am 42. Arxiva - Samekh 43. M:Pathy - Vacillate 44. Høst - Say You Love Me 45. Gravit-E/Jay - Mirror Man 46. Jappa & Lupo - Darkest Night 47. Leks - Booty So Big 48. Midst - Ill Get You 49. Bennie, Ozone - Throw Down 50. Dunk, Dread Mc - Killa Dub 51. Classifyed - Little Something Like This 52. Mitekiss - Fromu (Hospital) 53. Derrick & Tonika - Space Diver 54. Høst - Nightlife (feat. Taurri) 55. Bru-C - Playground 56. Viewer - How It Feels 57. Mosaic-Jigsaw 58. Mosaic-Jigsaw 59. A-Audio - Who Are Ya Bros 60. Finnadrift - Sipping Away 61. Alpha Rhythm, Rezilient, Leo Wood - One Day At A Time 62. Msdos - Madness (Mathematica) 63. Dj Marky, Javeon - All 4 U 64. Alexvnder - Repose (Alpha Rhythm Remix) 65. Nelver Nic Zigzag - Ember Lights 66. Foor, Ellie Evans - See You In June (Clsm Remix)

Molecular biologist Khady Sall returned to Senegal in 2018 after setting up Science Education Exchange for Sustainable Development (SeeSD), a non-profit organization she founded while a PhD student in the United States. SeeSD promotes science, technology, engineering, art and mathematics education to encourage scientific literacy and critical thinking in young people.Sall tells Akin Jimoh how her career experiences abroad made the return to Africa a daunting prospect. But working and living abroad has convinced her that science careers in Africa, and the cities where science takes place, should not follow US and European models.“If we're not authentic in being scientists, and not doing research that follows local problems and our local culture, then at some point, we will just become another US or another France, and that will be very boring. Hopefully that will not happen here. And then we will be vibrant and do a different kind of science. People will say: ‘Wow, why didn't this happen sooner?'”Togolese researcher Rafiou Agoro runs the African Diaspora Scientists Federation, a mentoring platform that connects African scientists based abroad with colleagues back home, from his base at Indiana University School of Medicine in Indianapolis. So far, Agoro and his team of 150 mentors have supported more than 100 scientists.“I was looking for any any opportunity to have an impact back home. A lot of people who are abroad are eager to do something back here. COVID has taught us distances matter less when it comes to education,” he says.This is the sixth episode in an eight-part podcast series hosted by Akin Jimoh, chief editor of Nature Africa. See acast.com/privacy for privacy and opt-out information.

This one took a little longer than planned but im back to end May with a load of new and exclusive dnb cuts 1. Division - Transcendent 2. Kidsonic - Evolve (Impact Music) 3. Rizzle - Nascent (Engage Audio) 4. Octavate - Teeth N Lips (Rollout Records) 5. Wingz & Submarine - Kernschmelze (Overview Music) 6. Re:Form - Shuttle (Sine Audio) 7. Dopplershift - Badbwoi (Koax Remix) (Echo Chamber) 8. Genic - Outsider (Dispatch Recordings) 9. OB - Mistakes (Precinct) 10. Note - In A Moment (Vandal Records) 11. A K A - Waiver (inHabit) 12. Amoss - Front Left (Flexout Audio) 13. NC-17 - Punch Drunk (Dispatch Recordings) 14. Molecular & Amoss - Questionable (Flexout Audio) 15. Tweakz - Schizo (Delta9 Recordings) 16. Entita - The Get Down (Hyperactivity Music) 17. Screamarts - One Wave (Dispatch Recordings) 18. Waeys - The Rush (Overview Music) 19. Des McMahon - Dread & Despair (Play Me Records) 20. Noisia & Black Sun Empire - Caps Lock (Vision) 21. Framer - Ashes of War (Transparent Audio) 22. TZ - Native (Integral Records)

Drive Up Your Heart Health - the AudiobookCLICK HERE TO GET THE FULL AUDIO-BOOKEmail us at: Expert@pe21.com.au to redeem any offers you listen to on a showConvert complex medical research into simple lessons, 100% guarantees to drive up your heart health and lower your clinical risk of a cardiovascular eventAs social media has grown in the past 20 years, the era or age I call Netflix, Uber Google and screens -  we are so more aware of celebrities in our community who go into hospital for a heart attack, stroke, bypass surgery and sadly on many occasions pass away with little or no notice, and almost always what we were considered to be a premature death.The big question is how do we tackle the number one cause of sickness disease and premature death - it doesn't just impact kings, sporting celebrities, and movie stars, but rather it is the disease most prevalent in every day people. It is robbing people blind of their quality of life and length of life.This audiobook is a step-by-step method based on the work of over 100 PhD's and medicine and health science research from across the world and the 35,000 lessons taught by the author and his health and physical education career since 1985.This full 7 hours of this audio-book is available by clicking this website.CLICK HERE TO GET THE FULL AUDIO-BOOKToday's episode:This is the sixth Critical Diagram inside THE PE TEACHERS HEALTH LAB that gets you to fall in love with your physical health and cause a decrease in your clinical risk from the world's biggest cause of sickness, disease and death - cardiovascular events. Today's episode is a 5 minute introduction to this concept. We go way deeper inside The PE Teachers Health Lab, which you can get with my new heart health audiobook and printed supplement.

北西卓磨さん(@tkitanishi)ゲスト回、後編。予算申請書の書き方、研究室のスタッフから独立ポジションに移るまでのこと、今後行っていく大規模記録・多変量解析の方針などについて伺いました（4/27収録） Show Notes: 日本語の作文技術 頭が赤い魚を食べる猫 北西さんが採択されたAMED-PRIME 永井先生 伊佐先生 先進科学研究機構の人事 Buzsakiラボ NR, 五十嵐さんに言わせると…の回 最近Communications Biologyに出した仕事 瞬間的に介入したとしても、いろんなことが起きる (Otchy et al) Discrete Attractor Dynamicsの仕事（Inagaki et al)　短期記憶を保つ神経細胞集団からの記録中にオプトで神経活動を阻害し、集団の活動がどうリカバリするかを見ることでアトラクタ構造を明らかにした仕事。 自然にあるディスクリートアトラクターの遷移を追った研究の例 パーコレーション（8.2を参照） パーコレーション理論を神経回路動態の解析に適用した例 Inside-out Internally generated…の論文 Internal シリーズその２ 同志社の櫻井先生 じっとしていても脳の中で内発的にアクティビティを出す (総説) Sensory input を変えたときのネットワーク遷移 (Jezek et al) Cross correlationとcanonical correlation analysis (CCA):Kordingの古典的総説 篠本先生の最近の仕事。Cross correlation解析をencoding model的にやったもの CCAの神経科学分野への応用に関するreview CCAの(数学的でない)意味付け解説(日本語) MoserラボのGridのトーラス論文 の解説回 Grid のモジュール (Stensola et al) 多様体 (Wikipedia)海馬の多様体1 (Nieh et al) 海馬の多様体2 (Rubin et al) 頭方向細胞の多様体 (Chaudhuri et al) 大量にカルシウムイメージング…の仕事 ２手先…：収録用のメモに書いてあった北西さんのコメント Editorial Notes: 申請書をロジカルにとか偉そうなことを言いながら、話を全然ロジカルにまとめられず。。まだ荒いですが、いろんな研究の方向性を考えています。ラボメンバー募集しています！（北西さん） 後半は研究デザインに関する哲学というか、今までの収録ではなかなか出来なかった抽象的な議論が出来てよかったです。今後はもっとしていきたい。（萩原） 図らずも先進科学機構PI回が続きましたがCOIはありません笑　北西さん、研究室立ち上げのお忙しい時期にありがとうございます！（宮脇）

Do you know that primary resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) occurs in approximately 20% to 30% of patients with EGFR-mutated non-small cell lung cancer (NSCLC), and acquired resistance is inevitable? Credit available for this activity expires: 5/23/2023 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/974097?src=mkm_podcast_addon_974097

In this episode, Dennis M. Bier MD Young Career Editor Kevin C. Klatt, PhD, RD speaks with Mark A. Levine, MD, Section Chief of the Molecular and Clinical Nutrition Section of the Digestive Disease Branch at the National Institutes of Health. Dr. Levine's laboratory conducts basic, translational and clinical research to better understand Vitamin C kinetics in health and disease and its potential role in disease prevention and treatment. In this episode, Dr. Levine details his groups' recently accepted publication titled “Abnormal urinary loss of vitamin C in diabetes: prevalence and clinical characteristics of a vitamin C renal leak”, detailing the pharmacokinetics of vitamin C during depletion-repletion studies in individuals with diabetes and non-diabetic controls, defining evidence for a vitamin C renal leak in diabetes and clinical predictors of such a phenomenon.Be sure to connect with us on twitter! NIH: @NIHClinicalCntr @NIDDKgov; AJCN: @AJCNutrition; Dr. Klatt: @kcklatt. Find all of the publications from the American Society for Nutrition (@nutritionorg; @jnutritionorg) at our website: https://nutrition.org/publications/.

geneticista, doutor em Genética, especialista em Genética Molecular, membro titular da Sociedade Brasileira de Genética Médica e Genômica e da Sociedade Brasileira de Pediatria, Salmo Raskin OMS confirma quase 100 casos de varíola dos macacos

Let's relax with more sleepy science from a woman so talented that the word “scientist” was coined to describe her. This time, we learn about all the forces holding us together.   Help us stay 100% listener supported! All supporters in May will be entered into a drawing for our first-ever SWAG! Details here: Patreon: https://www.patreon.com/boringbookspod Buy Me a Coffee: https://www.buymeacoffee.com/d5kcMsW   Read "On Molecular & Microscopic Science” at Project Gutenberg: https://www.gutenberg.org/ebooks/55886   Music: "Cosmic Tingles” by Lee Rosevere, licensed under CC BY   If you'd like to suggest a copyright-free reading for soft-spoken relaxation to help you overcome insomnia, anxiety and other sleep issues, connect on our website, boringbookspod.com.

Mother and daughter Louise and Mae Driscoll update listeners on their lived experience of primary immune deficiency. Professor Andrew Pask, Molecular, Cellular and Developmental Biology School of BioSciences, University of Melbourne, discusses a $5 million gift that brings de-extinction of the Tasmanian tiger one step closer. And in weekly science news, the team discusses octopuses suicidal reproduction behavoir, beak assisted three-limbed walking parrot, and the Hubble space telescope asteroid hunter project. With presenters Dr. Shane, Dr Laura and Dr Ailie.

Recorded 2022-05-21 19:30:41 DnB Radio Tracklisting: * Noppo - The Light* Alibi & Dunk - Rockers* FX909 - Like That* BobWhite - Fresh Look* BCee feat. Lucy Kitchen - Surfacing (LSB Remix)* Beat Merchants - Holy Tron* Exile & Mark XTC - Set You Free* Voltage & SHY FX feat. Agent Sasco - Amazing* FX909 - Blue Skank* Damageman - Nothing Fancy* Cloud Formation - Artic Sun* DJ Linky DJ Marnel - Chronic Dub* Jam Thieves feat. Tennin - Shapes In Motion* Seba & Blackeye - Thoughts Run Free* Noppo - Mist* Refracta - Grape* MidKnighT MooN - Soul Renagades* Jam Thieves & Magenta - Mammoth* Rezilient - Positive Reaction* Isaac Maya ft. Jamie Irie - Sweet Sensimilla (Brian Brainstorm Remix)* Cloud Formation - 7th Avenue* Creatures & Visionobi - Taboo* Frij - Liminal* Exile & Mark XTC - Scorpion* Bank - Deep Trouble* Furney feat. LADY EMZ - Hear Me* Maykors & Alyness feat. Oktae - Sad Piano* L'Entourloop feat. Alborosie & Promoe - Calling Dancers* Objectiv - Out The Block* Photek - Into The 90's* Oakley Grenell & Rider Shafique - Strictly Niceness (Midnight Dubs & LQ Remix)* Villem - Day Equals Night* Jam Thieves & Dub Elements - Wicked* Rezilient - Be With You* MidKnighT MooN - Music Itself* Villem feat. Tom Wardle - Last One Standing* Objectiv & Lupo - Decisions* Phabiaz - Passion In Eb* Meen - Photo Album Of Memories* Kubiks & S.O - Celebrate* The Funk Hunters & Stickybuds & Flowdan - Empire (Phibes Remix)* M-zine - Core* Noppo feat. RJD - Be Mine* Creatures & Molecular feat. Joe Raygun - Gonzo Transmission (Molecular Remix)* Fox & [ K S R ] & Satl - Sunshine Blues* Creatures & Philth - Love's Ghost* Bank - Guns Hot* One Mindz - Countdown* Stranger & NÜ - Sin Blaine* M-zine - Translucent* Rezilient & Luciano (DnB) - Distance* Fixate & dBridge - Programmed To Fail* Trex & Benny V - Tundra (Myth Remix)* Fixate - Must Be* Arkaik feat. Sense MC - Jewel In The Crown* Quentin Hiatus - Clever Girl* Cnof & Green Vibes - Golden Sketch* Leony - RemedyTracklisting:* Noppo - The Light* Alibi & Dunk - Rockers* FX909 - Like That* BobWhite - Fresh Look* BCee feat. Lucy Kitchen - Surfacing (LSB Remix)* Beat Merchants - Holy Tron* Exile & Mark XTC - Set You Free* Voltage & SHY FX feat. Agent Sasco - Amazing* FX909 - Blue Skank* Damageman - Nothing Fancy* Cloud Formation - Artic Sun* DJ Linky DJ Marnel - Chronic Dub* Jam Thieves feat. Tennin - Shapes In Motion* Seba & Blackeye - Thoughts Run Free* Noppo - Mist* Refracta - Grape* MidKnighT MooN - Soul Renagades* Jam Thieves & Magenta - Mammoth* Rezilient - Positive Reaction* Isaac Maya ft. Jamie Irie - Sweet Sensimilla (Brian Brainstorm Remix)* Cloud Formation - 7th Avenue* Creatures & Visionobi - Taboo* Frij - Liminal* Exile & Mark XTC - Scorpion* Bank - Deep Trouble* Furney feat. LADY EMZ - Hear Me* Maykors & Alyness feat. Oktae - Sad Piano* L'Entourloop feat. Alborosie & Promoe - Calling Dancers* Objectiv - Out The Block* Photek - Into The 90's* Oakley Grenell & Rider Shafique - Strictly Niceness (Midnight Dubs & LQ Remix)* Villem - Day Equals Night* Jam Thieves & Dub Elements - Wicked* Rezilient - Be With You* MidKnighT MooN - Music Itself* Villem feat. Tom Wardle - Last One Standing* Objectiv & Lupo - Decisions* Phabiaz - Passion In Eb* Meen - Photo Album Of Memories* Kubiks & S.O - Celebrate* The Funk Hunters & Stickybuds & Flowdan - Empire (Phibes Remix)* M-zine - Core* Noppo feat. RJD - Be Mine* Creatures & Molecular feat. Joe Raygun - Gonzo Transmission (Molecular Remix)* Fox & [ K S R ] & Satl - Sunshine Blues* Creatures & Philth - Love's Ghost* Bank - Guns Hot* One Mindz - Countdown* Stranger & NÜ - Sin Blaine* M-zine - Translucent* Rezilient & Luciano (DnB) - Distance* Fixate & dBridge - Programmed To Fail* Trex & Benny V - Tundra (Myth Remix)* Fixate - Must Be* Arkaik feat. Sense MC - Jewel In The Crown* Quentin Hiatus - Clever Girl* Cnof & Green Vibes - Golden Sketch* Leony - Remedy Download, Distribute, and Donate!

Buy/Stream: http://overview.fanlink.to/OVR054-Creatures Creatures trudges his way back to Overview with a colossal release in the form of Squid March. With 4 murky tracks in true Creatures style featuring collaborations with Philth, Visionobi and a hard remix of Gonzo Transmission by Molecular, this EP is another example of the Bristol artists immense talent and ability. Creatures www.facebook.com/creaturesdnb www.instagram.com/creaturesdnb/ https://soundcloud.com/creaturesdnb Overview Music https://overviewmusic.co.uk https://patreon.com/overview https://facebook.com/overviewuk https://instagram.com/overviewuk https://twitter.com/overviewuk https://soundcloud.com/overviewuk

No matter what specialised diet or treatment you undergo, we are all affected by aging and oxidative stress. In the medical field, treatments are widely reactive and target specific things like infections. However, health is more than just counteracting sickness — it should also be about helping our body regenerate!  There is now emerging research about hyperbaric oxygen therapy and its ability to help with sickness and improve general health. Hyperbaric oxygen therapy is not a cure-all miracle, however, it can help supply our bodies with the oxygen they need to repair and heal themselves!  In this episode, Dr Jason Sonners tackle common misconceptions about oxygen and hyperbaric oxygen therapy. Dr Jason discusses oxidative stress and what can make it positive or negative for our bodies. Hyperbaric oxygen therapy may not be widely used in hospitals, but the emerging research surrounding it shows incredible results. Take your health into your own hands and discover how hyperbaric oxygen therapy can improve your health! If you want to learn more about how hyperbaric oxygen therapy works, then this episode is for you! Get Customised Guidance for Your Genetic Make-Up For our epigenetics health programme, all about optimising your fitness, lifestyle, nutrition and mind performance to your particular genes, go to https://www.lisatamati.com/page/epigenetics-and-health-coaching/. Customised Online Coaching for Runners CUSTOMISED RUN COACHING PLANS — How to Run Faster, Be Stronger, Run Longer Without Burnout & Injuries Have you struggled to fit in training in your busy life? Maybe you don't know where to start, or perhaps you have done a few races but keep having motivation or injury troubles? Do you want to beat last year's time or finish at the front of the pack? Want to run your first 5-km or run a 100-miler? ​​Do you want a holistic programme that is personalised & customised to your ability, goals, and lifestyle?  Go to www.runninghotcoaching.com for our online run training coaching. Health Optimisation and Life Coaching Are you struggling with a health issue and need people who look outside the square and are connected to some of the greatest science and health minds in the world? Then reach out to us at support@lisatamati.com, we can jump on a call to see if we are a good fit for you. If you have a big challenge ahead, are dealing with adversity or want to take your performance to the next level and want to learn how to increase your mental toughness, emotional resilience, foundational health, and more, contact us at support@lisatamati.com. Order My Books My latest book Relentless chronicles the inspiring journey about how my mother and I defied the odds after an aneurysm left my mum Isobel with massive brain damage at age 74. The medical professionals told me there was absolutely no hope of any quality of life again. Still, I used every mindset tool, years of research and incredible tenacity to prove them wrong and bring my mother back to full health within three years. Get your copy here: https://shop.lisatamati.com/collections/books/products/relentless. For my other two best-selling books Running Hot and Running to Extremes, chronicling my ultrarunning adventures and expeditions all around the world, go to https://shop.lisatamati.com/collections/books. Lisa's Anti-Ageing and Longevity Supplements  NMN: Nicotinamide Mononucleotide, an NAD+ precursor Feel Healthier and Younger* Researchers have found that Nicotinamide Adenine Dinucleotide or NAD+, a master regulator of metabolism and a molecule essential for the functionality of all human cells, is being dramatically decreased over time. What is NMN? NMN Bio offers a cutting edge Vitamin B3 derivative named NMN (beta Nicotinamide Mononucleotide) that can boost the levels of NAD+ in muscle tissue and liver. Take charge of your energy levels, focus, metabolism and overall health so you can live a happy, fulfilling life. Founded by scientists, NMN Bio offers supplements of the highest purity and are rigorously tested by an independent, third-party lab. Start your cellular rejuvenation journey today. Support Your Healthy Ageing We offer powerful third-party tested NAD+ boosting supplements so you can start your healthy ageing journey today. Shop now: https://nmnbio.nz/collections/all NMN (beta Nicotinamide Mononucleotide) 250mg | 30 capsules NMN (beta Nicotinamide Mononucleotide) 500mg | 30 capsules 6 Bottles | NMN (beta Nicotinamide Mononucleotide) 250mg | 30 Capsules 6 Bottles | NMN (beta Nicotinamide Mononucleotide) 500mg | 30 Capsules Quality You Can Trust — NMN Our premium range of anti-ageing nutraceuticals (supplements that combine Mother Nature with cutting edge science) combats the effects of aging while designed to boost NAD+ levels. Manufactured in an ISO9001 certified facility Boost Your NAD+ Levels — Healthy Ageing: Redefined Cellular Health Energy & Focus Bone Density Skin Elasticity DNA Repair Cardiovascular Health Brain Health  Metabolic Health My ‘Fierce' Sports Jewellery Collection For my gorgeous and inspiring sports jewellery collection, 'Fierce', go to https://shop.lisatamati.com/collections/lisa-tamati-bespoke-jewellery-collection. Here are three reasons why you should listen to the full episode: Learn how hyperbaric oxygen therapy works as a panacea, and why it's different from simply breathing in oxygen.  Discover the benefits of hyperbaric oxygen therapy and how it can serve as positive oxidative stress to our bodies.  Understand the future of hyperbaric oxygen therapy research and how there's growing study into its applications and synergy with different therapies. Resources If you would like more information on purchasing or renting hyperbaric chambers please contact Lisa on lisa@lisatamati.com and she can advise you further. Gain exclusive access and bonuses to Pushing the Limits Podcast by becoming a patron!  Hyperbaric Environment: Oxygen and Cellular Damage versus Protection Hyperbaric Oxygen Therapy - Discussion between Dr Jason Sonners & Dr Mercola from the Take Control of Your Health podcast  Oxygen Under Pressure by Dr Jason Sonners Check out previous Pushing the Limit episodes:  Episode 230 - Exploring Ari of the Possible with Dr Joe Dituri  Episode 227 - Fighting Cancer and Other Diseases Using the Ketogenic Diet with Dr Dominic D'Agostino  Episode 170 - Search for the Perfect Amino Protein and Why So Many of Us are Deficient with Dr David Minkoff  Episode 116 - AMA with Dom D'Agostino, PhD, Part I of II: Ketogenic diet, exogenous ketones, and exercise Episode 120 – AMA with Dom D'Agostino, PhD, Part II of II: Ketosis for cancer and chronic disease, hyperbaric oxygen therapy, and the effect of ketosis on female health  Connect with Dr Jason: Website I NJ HBOT Center I Youtube I Email (drjasonsonners@hbotusa.com) Episode Highlights [02:53] Introduction to Dr Jason Dr Jason's background is in exercise physiology, chiropractic and nutrition.  When he got a herniated disc, he was confident in his and his wife's abilities to help him recover. However, it did not fully heal even after 18 months.  Dr Jason then happened to attend a chiropractic conference and discovered hyperbaric chambers. He took sessions for four days and immediately saw improvement. His experience made him want to better understand hyperbaric oxygen therapy.  [07:04] How Hyperbaric is Growing Despite its impact and effectiveness, hyperbaric is not widely used in hospitals.  Dr Jason explains this is largely because of politics and insurance. There's also a myth that oxygen is dangerous.  The medical profession typically uses antibiotics to heal wounds, but antibiotics focus on reducing infection risks and do not improve the healing response.  Typically, doctors and insurance companies do not bring access and awareness to hyperbaric. It's typically the patient.  Because of a large interest in hyperbaric, Dr Jason was able to set up 30 hyperbaric clinics last year.  [14:14] How Hyperbaric Acts as a Panacea Dr Jason emphasises that hyperbaric therapy does not cure anything, but it can help with general wellness since your cells use oxygen to make energy.  Even if you're 100% saturated with oxygen, it does not mean that you have the oxygen needed to heal or fuel certain systems.  In the full episode, Dr Jason explains how we never have a surplus of oxygen for regeneration.  Hyperbaric therapy can create a reservoir of oxygen in our bodies and improve oxygen absorption to feed the tissues that need it. The reservoir is used over a 10-hour period.  Hyperbaric chambers put oxygen under pressure, compressing the molecules until they're small enough to dissolve into tissues.  [20:36] How Oxygen and Pressure Works  When you go above sea level, it becomes harder to breathe.  This is not because there's less oxygen, but because of how pressure forces oxygen into your circulation.  Every time you breathe, red blood cells pick up oxygen molecules and take them where they're needed.  With hyperbarics, oxygen dissolves at a faster rate than the capacity of red blood cells. Oxygen then stays in the liquid.  Red blood cells cannot bring oxygen to damaged tissues, however, hyperbaric allows them access as it produces an excess of oxygen in the liquid. [23:01] Short-term and Long-term Benefits of Hyperbarics  Our cells use food to create NAD and oxidized NAD becomes the fuel for our cells. Hyperbarics helps increase oxidation and, therefore, more fuel or ATP production.  Long-term benefits of hyperbaric include immune system upregulation, stem cell release, angiogenesis, and rebuilding of blood vessels.  [25:48] Is There Such a Thing as Getting Out Too Quickly?  When divers get out of water too quickly, the danger is not from the oxygen but from nitrogen. Too much nitrogen can block blood vessels and choke arteries.  The level of nitrogen depends on how deep a hyperbaric chamber is. However, most hyperbaric environments do not contain nitrogen.  Dr Jason shares that leaving a hyperbaric chamber makes the body think it's becoming hypoxic, but it's not actual hypoxia.  This state drives the angiogenesis growth factors.  [30:39] Differences Between Short and Long Hyperbaric Sessions When working with athletes, Dr Jason uses short 20–30 minute sessions to give a boost.  The hyperbaric chamber puts you in a parasympathetic state in which your body slows down, relaxes, and heals.  Doing hyperbaric at night can help people sleep better.  Dr Jason shares that around 30% of people get stimulated instead after doing hyperbaric, so he recommends these people do hyperbaric in the morning.  [32:50] What Can Hyperbaric Help With?  Dr Jason shares that hyperbaric research is still in progress and may not provide in-depth insights into certain conditions.  Hyperbaric therapy works for necrotizing fasciitis and gangrene. Hyperbaric therapy helps to reduce microbe activity and breaks down biofilms that anaerobic organisms. Conceptually, hyperbaric therapy would also work on other anaerobic infections like H Pylori.  It also helps white blood cells kill both bacterial and viral infections. Hyperbaric therapy can also help with neuropathy, strokes, and TBI.  There is still little research on its effect on ALS and MS, but Dr Jason notes that since it's an ongoing process, hyperbaric therapy can only work if it's done aggressively.  [37:48] When is Oxidative Stress Beneficial or Detrimental?  Oxidative stress is the reason we're dying, but it also helps us.  Everything requires balance and reactive oxygen species help promote cell turnover.  There needs to be enough damage to stimulate healing. While oxidation from the outside environment destroys our bodies, oxidation from hyperbaric therapy increases mitochondrial performance.  As people get used to hyperbaric sessions, they can build a tolerance to oxidation from the outside environment.  [42:48] The Importance of Protocols Healthy people can use hyperbarics periodically as it's relatively safe.  For people with serious health concerns, it's important to have a good protocol to match different therapies together.  [46:28] How Does Molecular Hydrogen Work with Hyperbarics? Molecular hydrogen is not an antioxidant, but it can act like one. When oxidizing, our bodies sometimes experience incomplete combustion and create superoxide or free radicals.  Using molecular hydrogen mixes excess oxygen with excess hydrogen to reduce free radical production.  [49:41] Can Hyperbarics Help with COVID-19?  There's been a huge interest in hyperbarics to help manage COVID-19 since it can help improve oxygen saturation.  Viruses need to be contained by our immune system. We can typically live with viruses in our body without them expressing.  COVID-19 is a new type of infection so it takes longer for people's immune systems to get it under control.  Other dormant infections can surface since our immune systems are so depleted.  Hyperbarics can help refuel that immune system.  [56:29] Importance of Synergy  Senescence cells can help protect the DNA against oxidative stress.  Combining hyperbaric therapy with other autophagy-related therapies like fasting and keto can create a synergistic effect.  [1:00:15] Future of Hyperbarics and Epigenetics Research  Dr Jason has written a book and uses his YouTube channel to help dispel myths about hyperbarics.  He shares that most research focuses on high-pressure hyperbarics, but his practice shows that people see benefits at all pressures.  There is growing research comparing benefits at different pressures.  What you do now is going to affect the next generation. While intergenerational toxicity exists, you can also re-teach your cells to express a healthier version of themselves.  7 Powerful Quotes “Just like anything else, you need to know how to use [oxygen], how to operate it properly, how to keep it within a safe means and make it effective.” “This might not sound fabulous, but [oxygen] doesn't cure anything. It just helps with so many things.” “Not only do we have to exercise properly, but the framework of alignment, and posture, and all the pieces that predispose the body to breaking down prematurely, and where chiropractic fit the model of really trying to improve that story.” “I can only hold my breath for a couple minutes and if I can get a little bit more oxygen, maybe I could heal a little bit faster. To some extent, it's that simple.” “If we make really great changes, and then we decide to have children at some point, we may not have to pass down the intergenerational toxicity.” “Every virus you've ever had, you'll always have. They live contained, so to speak, and as long as our immune system can keep things in quarantine that way, we can typically live with these viruses in our body without actually expressing.” “Molecular hydrogen is technically not an antioxidant, but it has antioxidant-like capacity.” About Dr Jason Dr Jason Sonners, DC, DIBAK, DCBCN, CCWP, CHP is a certified hyperbaric practitioner and is the Clinic Director of NJ HBOT and HBOT USA. He combines hyperbaric oxygen therapy, exercise, nutrition, and detoxification programs to help support patients through a variety of conditions including autoimmune and neurological conditions, autism, allergies, cancer, and many others.  Passionate about spreading the effectiveness of hyperbaric oxygen therapy, Dr Jason wrote the book, Oxygen Under Pressure, and regularly uploads to the HBOT USA YouTube channel.  Learn more about Dr Jason and his work through his website, NJ HBOT Center, and Youtube. You can also contact him through email (drjasonsonners@hbotusa.com). Enjoyed This Podcast? If you did, be sure to subscribe and share it with your friends! Post a review and share it! If you enjoyed tuning in, then leave us a review. You can also share this with your family and friends so they can know the basics of hyperbaric oxygen therapy.  Have any questions? You can contact me through email (support@lisatamati.com) or find me on Facebook, Twitter, Instagram and YouTube. For more episode updates, visit my website. You may also tune in on Apple Podcasts. To pushing the limits, Lisa  

Understand how to reduce exposure risks and the importance of doffing PPE correctly. In this episode, Andy Starnes, Dr. Farzaneh Masoud, and Richard Kesler as this trio dives deep into THL & TPP, how to reduce inflammation and the future of gross decon.    WHAT YOU CAN EXPECT TO LEARN Effects of exposure within the body and cancer risks How to reduce cross contamination in the fire house  Why PPE is helpful and not a hinderance  The importance of proper doffing  Understand how firefighter PPE works  ABOUT OUR GUESTSDr. Farzaneh Masoud, Director of Research at IFSI, has earned her Ph.D. from University of Illinois Urbana-Champaign from Department of Molecular Biology. Dr. Masoud has a broad background in Molecular, Cell and Developmental biology as well as mammalian reproductive biology.  Her doctoral research focused on identifying factors that underlies cancer metastasis. Dr. Masoud has joined Illinois Fire Service Institute as the Director of Research in 2019, where she leads numerous research projects concerning the health and safety of firefighters.  Prior to joining IFSI, Dr. Masoud was leading large interdisciplinary projects at National Center for Supercomputing Applications (NCSA) as a Strategic Research and Proposal Development office and has served as an Interdisciplinary Research Development Officer. Richard Kesler, Deputy Director of Research Programs, focuses on biomechanics, and physical performance, specifically examining the physiological demands of firefighting activity and the impact of firefighting on the firefighter. Richard serves on the National Fire Protection Association Fundamentals of Fire Control Within a Structure Utilizing Fire Dynamics technical committee. He is also a physical training instructor for the Illinois Fire Service Institute's Basic Operations Firefighter Academy and teaches in numerous other fire service classes. Richard is a graduate of the University of Illinois with a Master of Science degree in Bioengineering and is currently pursuing his PhD in Kinesiology. Learn more about Fire-Dex products and services by visiting, www.firedex.comJoin the Conversation by Following Us at:Facebook: https://www.facebook.com/FireDexTwitter: https://twitter.com/firedexInstagram: https://www.instagram.com/firedexgear/

今年３月に東大先進科学機構で独立した北西卓磨さん(@tkitanishi) をゲストに、電気生理 × AAV 黎明期の様子、ノルウェー生活、SPD～スタッフ時代の研究について伺いました。後編に続く（4/27収録） Show Notes(完全版): 北西ラボHP 総合文化研究科先進科学研究機構 岡ノ谷ラボ（現帝京大） 博士の仕事 田代ラボ（現シンガポール） 田代ラボでのお仕事 の筆頭著者レビュー 2005年のオプト論文 PINP論文 (=OptoID or OptoTagging) 田代さんのERCグラント 利根川先生のエングラムの話 Open Ephys Kavli Institute (for Systems Neuroscience) Moserラボ 五十嵐さん 伊藤さん 上村さん 小金澤さん Menno Witterラボ Mor Ther. Generation and Characterization of Chimeric Recombinant AAV Vectors 学振SPD: 学振PD獲得者の中でも特に優れた人が取れるフェローシップ。2020年度に終了。 奥山さん 川島さん 田中さん 松尾ラボ（現・九大） Mayfordのところでのお仕事 Dupretのラボがやってた方向 Claustrumの仕事 Crick and Koch 2005. What is the function of the claustrum? 水関ラボ Subiculumのプロジェクト（水関ラボでのSci Adv） の解説記事（PDF注意） Klausbergerのventral CA1の仕事 256 chのプローブ（所謂Buzsaki256, PDF注意） AAV6が逆行性に感染する…の論文 Editorial notes: ヘッドセットのノイズキャンセリングのせいか、ところどころ音が妙に小さくなってしまいました。すみません。。ただ、お二人にのせられて (?)、いっぱい喋りました。とても楽しい時間でした。ありがとうございました！（北西さん） この収録直後にNeuropixelsデビューしました。とりあえず3本同時記録。実験自体は128chでやってた時とそんな変わらんな〜という感じ。 話の中でもありましたが in vivo自由行動下の電気生理記録ができる国内ラボが本当に増えてきましたね～（宮脇）

Learn 10 new words in the context of The Free Spirits of the Molecular World, and get to practice what you learn on the website. Take your English vocabulary to the next level.Practice what you learn on the website https://englishpluspodcast.com/word-power-the-free-spirits-of-the-molecular-world/Support English Plus and get Patron-only benefits https://www.patreon.com/dannyballanLinks to English Plus Vocabulary Building Book Series:Crossword Puzzle Vocabulary Building Book SeriesBuy on Amazon: https://www.amazon.com/dp/B09N2QGQS4Learn More: https://englishpluspodcast.com/crossword-puzzle-vocabulary-building-book-series/Word Search Games and Activities Book SeriesBuy on Amazon: https://www.amazon.com/dp/B09N2PVK1GLearn More: https://englishpluspodcast.com/word-search-games-and-activities-book-series/Support the show

On this weeks episode of Ask Dr Jessica, we are joined by a fellow pediatrician, Dr Inessa Grinberg.  In this conversation, we talk all about picky eaters.  What can be done about picky eaters? What strategies can parents use to help children eat a healthy diet?  In this discussion, we focus on how to help parents can make the eating experience with children less stressful, and more enjoyable. Dr. Grinberg is originally from the former Soviet Union. She moved to Los Angeles in her early teenage years and completed her undergraduate education in Molecular and Developmental Biology at the University of California. She then embarked on a combined MD/PhD program at the University of Chicago, receiving Honors in her medical studies and a PhD in Human Genetics.  Dr. Grinberg went on to complete her residency training in Pediatrics at UCLA.Dr. Grinberg currently works at Beverly Hills Pediatrics (www.beverlyhillspediatrics.com). Dr. Grinberg has been listed in Super Doctors 2016-present and was selected for the Top Doctors Award by the Los Angeles Magazine in 2019 .   She is also a devoted wife and mother to three incredible children.Dr Jessica Hochman is a board certified pediatrician, mom to three children, and she is very passionate about the health and well being of children.  Most of her educational videos are targeted towards general pediatric topics and presented in an easy to understand manner. Do you have a future topic you'd like Dr Jessica Hochman to discuss?  Email your suggestion to: askdrjessicamd@gmail.com. Dr Jessica Hochman is also on social media:Follow her on Instagram: @AskDrJessicaSubscribe to her YouTube channel! Ask Dr JessicaSubscribe to this podcast: Ask Dr JessicaSubscribe to her mailing list: www.askdrjessicamd.comThe information presented in Ask Dr Jessica is for general educational purposes only.  She does not diagnose medical conditions or formulate treatment plans for specific individuals.  If you have a concern about your child's health, be sure to call your child's health care provider.

Should you use artificial intelligence to lead your team? This question may seem straight out of science fiction, but it's actually a burning question that top companies are asking around the globe today. I host IBM's first Global Chief AI Officer, Seth Dobrin, on the show, and he shares three steps that every leader should take to create an AI strategy. In his role, Seth leads IBM's corporate AI strategy and is responsible for connecting the development and governance of AI across IBM's business units with a systemic creation of business value. The commitment to human-centered AI prompted Seth to create a new methodology that helps companies develop AI strategies built on trust, providing business outcomes that are more fair, more accurate, and focused on real humans' needs. This methodology has helped elevate AI from being simply a tool used to make processes more efficient to an overarching catalyst of business transformation. Seth was recognized as AI Innovator of the Year 2021 at the AIconics Awards and named one of Corinium's Top 100 Leaders in Data & Analytics 2022. He has his undergraduate degree in Microbiology and a PhD in Molecular and Cellular biology from Arizona State University. LinkedIn Profile: https://www.linkedin.com/in/sdobrin Company Link: https://www.ibm.com What You'll Discover in this Episode: The important difference between AI and Machine Learning. If you should be worried about being “AI'ed” out of a job and what to do about it. Three steps to build an AI strategy for your team. Surprising places you'd never expect AI. The science fiction that inspired him as a kid. The one course he requires his kids to take (and why we should all take it ourselves). Why you should consider applying for a job if you're only 70% qualified. How AI can help leaders declare their vision (and it's limitations). The guiding principle for how leaders should use AI. Helpful gadgets for leaders. Quotes: “AI won't replace managers and leaders, but managers and leaders who use AI will.” ----- Connect with the Host, #1 bestselling author Ben Fanning https://www.benfanning.com/speaker/ (Speaking and Training inquires) https://followbenonyoutube.com (Subscribe to my Youtube channel) https://www.linkedin.com/in/benfanning/ (LinkedIn) https://www.instagram.com/benfanning1/ (Instagram) https://twitter.com/BenFanning1 (Twitter)

Carles Mesa charla “Mano a mano” con el actor y dramaturgo Alberto Velasco. Hablamos sobre el monólogo Sweet Dreams, que está representando en el espacio Nave 73 de Madrid; y de la obra Atra Bilis, de la que es director, y que se puede ver en el Teatro Infanta Isabel de la capital. Después, resolvemos y planteamos una nueva pregunta relacionada con la actividad del Consejo Superior de Investigaciones Científicas (CSIC). Esta semana hablamos sobre el comienzo de la tercera fase de funcionamiento del Gran Colisionador de Hadrones (LHC), situado en Ginebra. Escuchamos a la física Alicia Calderón, investigadora y profesora del Instituto de Física de Cantabria (IFCA-CSIC-UC). Es la responsable, junto a Celso Martínez, de la parte de análisis de datos. Después, en “El Podio” de Olga Viza abrimos un nuevo capítulo de ciencia aplicada al deporte con el catedrático de Bioquímica y Biología Molecular de la Universidad de Murcia (UMU) José Manuel López Nicolás. Escuchar audio

En “El Podio” de Olga Viza abrimos un nuevo capítulo de ciencia aplicada al deporte con el catedrático de Bioquímica y Biología Molecular de la Universidad de Murcia (UMU) José Manuel López Nicolás. Escuchar audio

The boys hit the airwaves with one of their favorites, Jan Andersson, President of MrPEX. It doesn't take long to get right to the important stuff, how many people mistake him as Metallica's lead singer James Hetfield. Yes, Jan is definitely his doppelganger. Music, Minnesota, Molecular Musings with MrPEX and maybe even a little Rock Camp for Dad discussion are the focus of this week's NDY Podcast.

Kaajal Agnani, Founder and CEO of Boundless Blooms is on a mission to inspire the next generation of kindful (kind + mindful) humans. Launching her business has been a true labor of love for Kaajal, one where she's been able to combine years of experience in research, marketing, and operations with her passion for children's education and development. Yoga, meditation, and mindfulness have played an instrumental role in her life. She knew that her first products had to achieve a specific aim: to make mindfulness meditation fun and accessible for kids of all ages. Since launching, Boundless Blooms has partnered with non-profit organizations, schools, and university programs to make mindfulness accessible to thousands of kids across the country. Kaajal holds a BA in Molecular and Cell Biology from the University of California, Berkeley and an MBA from the University of Southern California (where she studied mindfulness). She currently lives in Los Angeles with her partner, Raja, vibrant toddler, Zavi, and sweet baby, Ayaan.Topics discussed:- The inspiration behind Boundless Blooms, and how she came up with the idea for the Mindful Moments card deck and the Good Morning, Good Morning book- Tips on how parents and caregivers can incorporate mindfulness into daily life- The mission and vision for Boundless Blooms- How Kaajal donates her time and product to make my mindfulness resources accessible to children in underserved communities and throughout the country since the pandemic beganGet in touch with Kaajal:https://www.instagram.com/bloomkindfullyhttps://www.instagram.com/klaungani www.boundlessblooms.worldMeet your hosts:Sue McCarroll is the founder of Opal Wellness Studio and Caitlin Hatzenbuhler is the founder of Conscious Core. Caitlin and Sue have their unique styles of coaching women to increase self-care, self-compassion, navigate busy mom life and nourish their bodies mentally, emotionally, and physically. You can learn more about Sue at https://www.instagram.com/opal_wellness_studio/and Caitlin at https://www.instagram.com/conscious_core_caitlinThank you for listening! Please take a moment to subscribe and review.This supports the Well2You Podcast in reaching more people who need to be connected to these impactful conversations.https://podcasts.apple.com/us/podcast/well2you-podcast/id1547156150?i=1000504170074 https://open.spotify.com/show/7AE1vZFmBoxPvYfn5Abr1T?si=RjrXrOWoToKvZ5bmCcJSgw https://www.well2you.org/well2you-podcast

La física cuántica es uno de los grandes logros del conocimiento humano y es la base de la comprensión de los fenómenos naturales a escala atómica. Aunque las bases de la física cuántica se conocen desde hace mucho tiempo es ahora cuando los expertos señalan que estamos ante el comienzo de una revolución en la física, que traerá avances muy importantes en campos como las comunicaciones, la medicina y los ordenadores entre otros. Esta semana hablamos de la física cuántica y sus aplicaciones con María Victoria Fonseca, catedrática Honorífica de Física Atómica, Molecular y Nuclear de la Universidad Complutense de Madrid; Elena Yndurain, profesora en IE University, responsable de la expansión a Europa de QunaSys, una startup japonesa de algoritmos cuánticos, y Alba Cervera-Lierta, investigadora del Barcelona Supercomputing Center - Centro Nacional de Supercomputación (BSC-CNS) y coordinadora del proyecto Quantum Spain, iniciativa para impulsar el ecosistema de computación cuántica español. Escuchar audio