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¿Pérdida de memoria o falta de atención? Olvidar nombres, distraerte o decir “¿a qué venía?” no siempre es normal.En este episodio hablamos de memoria, atención, envejecimiento del cerebro y hábitos diarios que influyen mucho más de lo que imaginas. No para asustarte, sino para ayudarte a distinguir entre lo común, lo normal y lo que sí conviene atender a tiempo.Me acompaña el Dr. Erwin Chiquete, neurólogo y doctor en Biología Molecular, quien te explica cuáles son las señales tempranas del deterioro cognitivo, qué mitos debemos dejar atrás y cómo cuidar tu mente desde hoy.La memoria necesita energía, calma y buen funcionamiento interno. Si tu pancita no está bien, tu cerebro trabaja a medias.Por eso quiero invitarte a sanar desde la raíz en el Reto Sana tu Pancita y Vive Feliz.
In this episode of the Epigenetics Podcast, we talked with Peggy Farnham from the Keck School of Medicine at USC about her work on establishing the ChIP Method in mammalian cells. In this episode, we dive into the relationship between transcription factors, chromatin dynamics, and gene expression with Professor Peggy Farnham from the Keck School of Medicine at USC. Professor Farnham shares her profound insights into how her groundbreaking research has reshaped our understanding of gene regulation and its implications in cancer. We explore how she has been a pioneer in mapping the genome-wide landscape of regulatory proteins, illuminating the molecular logic behind transcriptional control and its disruption in cancer biology. The interview starts with her instrumental role in adapting chromatin immunoprecipitation (ChIP) technology from yeast to human cells. Professor Farnham reflects on the technical challenges she faced during this transition, such as the quest for visibility of signals in mammalian systems. Her ability to innovate and troubleshoot challenges led to significant advancements in techniques that allow for the rapid identification of transcription factor binding sites, fundamentally changing the landscape of epigenetic research. As the discussion progresses, we learn about Professor Farnham's active involvement in the ENCODE project, where she contributed to high-resolution mapping of transcription factors and regulatory elements in human cells. She articulates her appreciation for collaborative efforts in science, highlighting how working within a consortium harnesses the collective expertise of diverse research groups. This collaboration not only bolstered the credibility of the data produced but also propelled the field forward in understanding the complexity of gene regulation. Through her participation in various projects, such as the Psyc-ENCODE consortium and the Roadmap Epigenome Mapping Consortium, Professor Farnham shares insights into her investigation of epigenetic variations, particularly in relation to complex disorders like schizophrenia. Her findings underscore the nuances of enhancer variability among individuals and the implications for understanding disease mechanisms, thereby advancing our knowledge of genetic regulation and its contributions to diverse biological outcomes. Moreover, the episode highlights Professor Farnham's reflective understanding of emerging technologies in the field. She discusses the evolution of methods that allow researchers to investigate gene regulation at single-cell resolution, recognizing the significant implications these innovations have for our comprehension of cellular differentiation and the transcriptional landscape. References Weinmann AS, Bartley SM, Zhang T, Zhang MQ, Farnham PJ. Use of chromatin immunoprecipitation to clone novel E2F target promoters. Molecular and Cellular Biology. 2001 Oct;21(20):6820-6832. DOI: 10.1128/mcb.21.20.6820-6832.2001. PMID: 11564866; PMCID: PMC99859. Wells J, Farnham PJ. Characterizing transcription factor binding sites using formaldehyde crosslinking and immunoprecipitation. Methods (San Diego, Calif.). 2002 Jan;26(1):48-56. DOI: 10.1016/s1046-2023(02)00007-5. PMID: 12054904. Rhie SK, Schreiner S, Witt H, et al. Using 3D epigenomic maps of primary olfactory neuronal cells from living individuals to understand gene regulation. Science Advances. 2018 Dec;4(12):eaav8550. DOI: 10.1126/sciadv.aav8550. PMID: 30555922; PMCID: PMC6292713. Tak YG, Hung Y, Yao L, et al. Effects on the transcriptome upon deletion of a distal element cannot be predicted by the size of the H3K27Ac peak in human cells. Nucleic Acids Research. 2016 May;44(9):4123-4133. DOI: 10.1093/nar/gkv1530. PMID: 26743005; PMCID: PMC4872074. Related Episodes The Effect of lncRNAs on Chromatin and Gene Regulation (John Rinn) CpG Islands, DNA Methylation, and Disease (Sir Adrian Bird) The Future of Protein–DNA Mapping (Mitch Guttman) MLL Proteins in Mixed-Lineage Leukemia (Yali Dou) Contact Epigenetics Podcast on Mastodon Epigenetics Podcast on Bluesky Dr. Stefan Dillinger on LinkedIn Active Motif on LinkedIn Active Motif on Bluesky Email: podcast@activemotif.com
We don't need to hide.Our guest this week shares this message loud and clear: as providers, we have nothing to hide from our patients.Dr. Erica Urquhart knows a thing or two about our healthcare system - having trained at Harvard as a biomedical engineer, she received a MD-PhD in Molecular and Neuroscience from Johns Hopkins and is now a practising orthopedic surgeon.She joins today to talk through her outlook on a broken system, as told in her upcoming book ‘Invisible Hand Wielding the Scalpel: Paying the Price in America's Fractured Healthcare System'.—We spoke about the value of transparency in healthcare, her constant battle with massive insurance companies, the capitalist emphasis in the system, the influence of commercial insurers in driving the cost and accessibility of care, and the fundamental importance of sickness prevention.Follow me on Instagram and Facebook @ericfethkemd and checkout my website at www.EricFethkeMD.com. My brand new book, The Privilege of Caring, is out now on Amazon! https://www.amazon.com/dp/B0CP6H6QN4
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Mark Heath is joined by Stuart Watson and Alex Jones to discuss all things Ipswich Town.The boys kick off with a deep dive into sexy stuff, including what's happened so far and the state of the squad with just days left in the window.Then it's on to multiple striker links and our thoughts on each, plus the news that Sammie Szmodics could be departing.We finish with a look at Saturday's home clash with Preston, debate who should start and offer our predictions.Plus, Stu reveals a spiky birthday gift and Mark offers up a recipe for a banging protein smoothie.Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/Also sponsored by Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Ross Halls and Tom Cann are back with our Ipswich Town Women's podcast.The duo discuss the appointment of Sean Burt as technical director and four new signings. They chat about the big point against Bristol City, the key taking points and standout performers. Plus hear thoughts from interim manager David Wright and forward Natasha Thomas. Then look ahead to two big away trips to Newcastle and Portsmouth. Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/Also sponsored by Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Ross Halls is joined by Stuart Watson to discuss Ipswich Town's loan signing of midfielder Dan Neil from Premier League club Sunderland.The 24-year-old becomes the Blues' second signing of the January transfer window and moves to Portman Road on a deal until the end of the season.The boys chat about his journey at his boyhood club, where he will fit in and attributes as a player. They also speak about the balance of the squad, who could leave before deadline day and where the Blues might strengthen next.The duo take questions and comments from the audience and much more.Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/Also sponsored by Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Mark Heath and Alex Jones gather to reflect on a deflating result at Bramall Lane for Ipswich Town.The boys talk through the game and the key moments, discuss the changes to the starting XI and lament old problems resurfacing. There's also a chat about Town losing their heads, the form of George Hirst and Sindre Walle Egeli, Anis Mehetmi's debut and Dara O'Shea's post-match comments.Then it's onto sexy stuff, with the link to Sunderland's Dan Neil and AJ's latest thoughts on the need to add a striker in the last week of the window.Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/Also sponsored by Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Alex Jones is joined by Stuart Watson to discuss Anis Mehmeti's £3m move from Bristol City to Ipswich Town.The boys discuss the deal, which sees Kieran McKenna's side bolster their attacking line for the second half of the season and beyond.But where will Mehmeti fit in? There's a chat about the balance of the squad, who could leave before deadline day and where the Blues might strengthen next.AJ and Stu also take questions and comments from supporters, discussing whether or not they think the 25-year-old will be a hit at Portman Road.Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/Also sponsored by Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
NASA is developing a process that could separate oxygen from solid metals in the dust and rock on the Moon.
Ibogaine has surged in popularity as a topic due to its potential to target addiction, trauma and more. But as is always the case with sensational topics, much of what you hear may be false. In this episode, we sit down with a world expert on the topic to understand what is known about this powerful molecule and what is still to be discovered as well as risks and opportunities. Dr. Deborah C. Mash is a Professor of Neurology (Emeritus) and Molecular and Cellular Pharmacology at the University of Miami School of Medicine. Her work has received decades of NIH funding from the National Institute on Drug Abuse. She is a pioneer in the research on the psychedelic molecule ibogaine and discovered its metabolite noribogaine. She leads DemeRx, a company that is advancing clinical development of noribogaine. This episode was recorded live at the @EudemoniaSummit Learn more about this amazing in-person event here: https://bit.ly/4rbToP7
LINEAR SYSTEM IS A TECHNO ARTIST KNOWN FOR HIS HYPNOTIC AND IMMERSIVE SIGNATURE SOUND, BLENDING DEEP, LAYERED TEXTURES WITH POWERFUL BASSLINES. EMERGING FROM SPAIN IN 2020, HE QUICKLY GAINED RECOGNITION FOR HIS DISTINCT APPROACH TO TECHNO, CRAFTING INTRICATE, EVOLVING SOUNDSCAPES THAT CAPTIVATE LISTENERS. HIS PRODUCTIONS REACHED LABELS LIKE PLANET RHYTHM, MOLECULAR, DYNAMIC REFLECTION, SYMBOLISM, EDIT SELECT...HIS MUSIC IS CHARACTERISED BY A DARK YET DYNAMIC ENERGY, REFLECTING HIS DEDICATION TO PUSHING THE BOUNDARIES OF THE GENRE. WITH PERFORMANCES ACROSS THE GLOBE, HE HAS BROUGHT HIS VISION TO RENOWNED CLUBS AND FESTIVALS, CONNECTING WITH AUDIENCES THROUGH HIS DEEP, DRIVING RHYTHMS AND ATMOSPHERIC INTENSITY. IN 2023 HE STARTED HIS OWN LABEL, MODERN MINIMAL RELEASING MUSIC EXCLUSIVELY FOR FREE Tracklist via -Spotify: bit.ly/SRonSpotify -Reddit: www.reddit.com/r/Slam_Radio/ -Facebook: bit.ly/SlamRadioGroup Archive on Mixcloud: www.mixcloud.com/slam/ Subscribe to our podcast on -iTunes: apple.co/2RQ1xdh -Amazon Music: amzn.to/2RPYnX3 -Google Podcasts: bit.ly/SRGooglePodcasts -Deezer: bit.ly/SlamRadioDeezer Keep up with SLAM: https://fanlink.tv/Slam Keep up with Soma Records: https://linktr.ee/somarecords For syndication or radio queries: harry@somarecords.com & conor@glowcast.co.uk Slam Radio is produced at www.glowcast.co.uk
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Mark Heath and Stuart Watson return to discuss all things Ipswich Town after their 2-0 win over Bristol City at Portman Road.The boys reflect on the game's key moments, praise Jack Clarke and Ivan Azon, and hear from both Kieran McKenna and the popular Spaniard.There's also chat around Wes Burns' remarkable comeback, Sam Morsy's return to Portman Road and further debate about Town's need for a striker after a suggestion that we were ‘talking b*llocks' on Monday's show.We finish with an injury update and brief look ahead to Sheffield United - plus an update on Stu's metal detecting career and an apology from Mark.Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/Also sponsored by Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Guest: Dr Dylan Williams, Principal Research Fellow in Molecular and Genetic Epidemiology at UCL
Dr. Bryan Cassone is a Professor and Chair in the Department of Biology at Brandon University in Canada. He is a molecular entomologist. Drawn to the sheer variety of fascinating questions insects can help answer, he is more of a generalist than many scientists in his field. His work spans agricultural and medical pests, plus curiosity-driven projects like studying waxworms (plastic-eating caterpillars). Outside the lab, Bryan is a big football fan. After playing football and wrestling in college, Bryan now loves watching both college and NFL games. He also enjoys staying active with swimming and weight training, and he loves traveling to new places. Bryan received his B.Sc. in biology, specializing in environmental science, from the University of Western Ontario, his M.Sc. in integrative biology from the University of Guelph, and his Ph.D. in biological sciences from the University of Notre Dame. After completing his PhD, Bryan conducted postdoctoral research at the Corn, Soybean, & Soft Wheat Unit at the United States Department of Agriculture. Next, he was a CAPS Herta Camera Gross Postdoctoral Fellow in the Department of Plant Pathology at Ohio State University. He joined the faculty at Brandon University in 2015. In this interview, Bryan shares more about his life and science.
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
New host Ross Halls is joined by Alex Jones and Mark Heath to discuss all things Ipswich Town.The boys chat about the latest transfer links, including Kendry Paez and Tom Cairney, plus ponder if Town's lack of business should be a concern.Then we reflect on a horrific (trademark AJ) FA Cup draw and take loads of your questions in Mailbag.We finish with a mini Blackburn preview and our predictions.Plus, news of Alex's criminal record and an update on Rossi's treachery.Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/Also sponsored by Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Ross Halls is joined by Stuart Watson and Alex Jones to discuss Ipswich Town's 2-1 win against Blackpool in the FA Cup.The boys reflect on the Portman Road clash against the League One side, with Jaden Philogene scoring a trademark opener before Jacob Greaves killed the game off ahead of a controversial penalty.There's chat around the key themes - Jack Clarke playing in the no.10 role, how to balance the defence and breaking down low blocks ahead of an intriguing run of games.Then it's onto tonight's fourth round draw and some transfer chat, while Rossco sheepishly tries to establish himself as the new full-time host of the podcast.Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/Also sponsored by Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
SpaceTime with Stuart Gary | Astronomy, Space & Science News
SpaceTime with Stuart Gary Gary - Series 29 Episode 4In this episode of SpaceTime, we explore the latest revelations about supermassive black holes, the enigmatic interstellar comet 3I Atlas, and NASA's innovative tests on lunar surface interactions.Do All Galaxies Host Supermassive Black Holes?A groundbreaking study utilizing NASA's Chandra X-ray Observatory challenges the long-held belief that all galaxies harbor supermassive black holes at their centers. Analyzing data from over 1,600 galaxies, researchers discovered that only about 30% of dwarf galaxies contain these cosmic giants. The findings, published in the Astrophysical Journal, provide crucial insights into the formation of supermassive black holes and suggest that smaller galaxies may have significantly fewer black holes than their massive counterparts.No Evidence of Alien Intelligence from Comet 3I AtlasDespite sensational claims, a thorough investigation into the interstellar comet 3I Atlas has yielded no signs of extraterrestrial technology. Observations from the Green Bank Radio Telescope during the comet's closest approach revealed only radio frequency interference, dismissing earlier speculations of alien signals. The analysis reinforces the understanding that the comet's behavior aligns with natural phenomena, rather than advanced civilizations.NASA's Rocket Plume Studies on Lunar RegolithNASA is conducting new experiments to understand how rocket plumes interact with the lunar surface, crucial for future lunar landings. Using a sophisticated camera system, scientists are simulating rocket engine behavior in a vacuum chamber to analyze the impact of exhaust on lunar dust and rocks. The data collected will inform the design of landing systems for the Artemis missions and future Mars explorations, ensuring crew safety and mission success.www.spacetimewithstuartgary.com✍️ Episode ReferencesAstrophysical JournalNASA ReportsJournal of Molecular and Cellular BiochemistryBecome a supporter of this podcast: https://www.spreaker.com/podcast/spacetime-your-guide-to-space-astronomy--2458531/support.(00:00:00) This is Space Time Series 29, Episode 4 for broadcast on 9 January 2026(00:00:47) Study reveals fewer supermassive black holes in smaller galaxies(00:12:30) No signs of alien technology from comet 3I Atlas(00:20:10) NASA's lunar regolith plume interaction tests(00:25:00) Science report: Microplastics and neurodegenerative diseases, dog ownership and community ties
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Ross Halls caught up with former Ipswich Town midfielder Lee Evans to discuss his time at Portman Road in our Kings of Anglia podcast special.Lee is set to return to the club for the first time since his departure in 2024 as his Blackpool side face the Blues in the third round of the FA Cup.He spoke about a range of memories from his time at Town, such as being one of the 19 summer signings in 2021, reuniting with Paul Cook, early struggles and his hat-trick against Doncaster. The Welshman also discusses his relationship with Kieran McKenna, injury setbacks, winning promotion, living in Suffolk, his departure and much more. Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/Also sponsored by Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/NYM865. CME/MOC/NCPD/CPE/AAPA/IPCE credit will be available until December 10, 2026.Calibrating Clinical Approaches for Metastatic Colorectal and Lung Cancers: Insights on Molecular Testing and BRAF Inhibitors in Community Settings In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Pfizer.Disclosure information is available at the beginning of the video presentation.
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/NYM865. CME/MOC/NCPD/CPE/AAPA/IPCE credit will be available until December 10, 2026.Calibrating Clinical Approaches for Metastatic Colorectal and Lung Cancers: Insights on Molecular Testing and BRAF Inhibitors in Community Settings In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Pfizer.Disclosure information is available at the beginning of the video presentation.
Cofounders Jeremy Wohlwend and Gabriele Corso join the a16z podcast to discuss the launch of Boltz, a public benefit company building AI infrastructure for molecular biology. The conversation explains how breakthroughs following AlphaFold moved the field beyond protein structure prediction into modeling biomolecular interactions and binding strength, why open-source Boltz models saw rapid adoption across pharma and biotech, and how that work is now being productized. They outline the launch of Boltz Lab, a platform that brings protein and small-molecule design agents into scientist workflows, Boltz's decision to operate as an infrastructure company rather than a therapeutics company, and how AI could reduce early drug discovery bottlenecks by improving molecular design and speeding iteration between computation and the lab. Resources: Follow Gabriele on X: https://twitter.com/GabriCorso Follow Jeremy on X: https://twitter.com/jeremyWohlwend Follow Jorge X: https://twitter.com/jorgecondebio Follow Zak on X: https://twitter.com/zakdoric Stay Updated:If you enjoyed this episode, be sure to like, subscribe, and share with your friends!Find a16z on X:https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zListen to the a16z Podcast on Spotify: https://open.spotify.com/show/5bC65RDvs3oxnLyqqvkUYXListen to the a16z Podcast on Apple Podcasts: https://podcasts.apple.com/us/podcast/a16z-podcast/id842818711Follow our host: https://twitter.com/eriktorenberg](https://x.com/eriktorenbergPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Ross Halls is joined by Stuart Watson and Alex Jones on the latest Kings of Anglia podcast.The boys discuss the January transfer window, with Sheffield United's Patrick Bamford linked, while Aro Muric is reportedly attracting one of the biggest clubs in Europe.Then it's onto the state of the squad. Who could support Azor Matusiwa in midfield, and which players could head out on loan?There's chat around Saturday's FA Cup tie against Blackpool. Do the Blues need a run, and who could start at Portman Road?There's also a running theme of claret, with Ross setting a kit-based challenge for the pod.Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/Also sponsored by Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Ross Halls and Tom Cann are back with our Ipswich Town Women's podcast to discuss Joe Sheehan's departure. The duo share their instant reaction to the breaking news, overall thoughts on the decision and the season so far. They chat about the legacy he will leave behind, what's next for the club and look ahead to the first game of 2026. Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/Also sponsored by Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Orsolya (Orsi) Lazar is an urban forester, an ISA Certified Arborist and a Pennsylvania (PA) Certified Horticulturalist in Sustainable Landscapes. Her unconventional path to forestry began with a Master's Degree in Ecology and a Master's Degree in Molecular and Cell Biology. She has over 20 years of experience in landscape design and management, project management, and education.Orsi became the first Community Tree Specialist at Pennsylvania DCNR's Urban and Community Forestry Program. She helps shape this growing program to better serve communities by building trust, identifying opportunities, and finding creative solutions to challenges. She works with municipalities and non-profits toincrease tree benefits, manage costs and risks, and creates green spaces that suit people's needs.She is a member of the Pennsylvania Landscape and Nursery Association and is in the group that is working on updating the PA Certified Horticulturist study manual.Orsi has taught gardening and tree care for diverse audiences, including workforce developmentprograms. Many local parks have benefited from her technical assistance and plant donations. She created a tree inventory and installed hundreds ofbotanical signs at Merion Botanical Park as a pro bono contribution to her own community. Her “Responsible Gardening” Facebook group helps local gardenersconnect and share sustainable, evidence-based practices.When not in the garden or a park, she enjoys teaching tricks to her border collie or is on the dance floor practicing ballroom and Latin dancing.
This podcast is brought to you by Outcomes Rocket, your exclusive healthcare marketing agency. Learn how to accelerate your growth by going to outcomesrocket.com Accessible diagnostics isn't a luxury anymore; it's the missing link preventing millions from receiving timely care. In this episode, James York, Chief Commercial Officer and Head of Government Affairs for Molecular Testing Labs, discusses how reimagining the patient journey can remove the economic, geographic, and emotional barriers that keep people from getting essential tests. He explains how at-home self-collection, transparent pricing, and frictionless access are transforming diagnostics, especially for conditions like HIV, STIs, chronic disease markers, and wellness indicators. James walks through the challenges of pioneering new models in healthcare, including regulatory hurdles, industry resistance, and the realities of scaling without major outside funding. He also explains why affordability is inseparable from access, how virtual care has shifted expectations, and why focusing on everyday tests, not cutting-edge technology, is where the greatest impact lies. Tune in and learn how simplifying diagnostics can unlock a more equitable, consumer-centered healthcare system! Resources Connect with and follow James York on LinkedIn. Follow Molecular Testing Labs on LinkedIn and visit their website!
Episode 409 of The VentureFizz Podcast features Ilia Papas, serial entrepreneur and co-founder of Band and Blue Apron. Do you know what the enchilada factor is? Probably not… unless you were part of the Blue Apron team that created a national brand and one of the pillar companies in the meal-kit food delivery category that ultimately went public. In this interview, Ilia shares the inside look at those hypergrowth years, including the company's use of machine learning for planning labor and food ordering, so they could fulfill those enchilada orders (also known internally as the enchilada factor) which always caused a spike when it was offered on the menu. Ilia's latest company is Band—and no, it's not the musical kind. Instead, the company is focused on a massive, underserved sector where trillions of dollars flow between businesses, yet technical innovation has been severely lacking. Band has built the smart operating system for B2B trade agreements, providing AI-powered rebate and incentive tracking for distributors, manufacturers, and purchasing groups. In this episode of our podcast, we cover: * Ilia's background story, plus the details on his siblings and their collective success in the tech industry. * Interning at his brother Art's company, Bullhorn, and then building the foundation of his career at web consulting firms like Molecular and Optaros, where he worked on the original version of Rue La La. * How he met his co-founder, Matt Salzburg, and why they pivoted from a “Kickstarter for science” idea to food delivery in 2012. * Bringing on a third co-founder, Matt Wadiak, who brought the culinary expertise and why they names the company Blue Apron. * Their approach to growth marketing to compete against HelloFresh & Plated and scaling to millions of meals a week. * The story of the IPO in 2017 and the unique challenges of running a publicly traded company * All the details about Band and why Ilia chose this underserved industry, plus how his approach to building a company is different this time around. * And so much more!
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Mark Heath and Alex Jones convene on a snowy Monday to talk all things Ipswich Town. The boys start by reflecting on the Portsmouth postponement, communication around it and when the game might be played now. Then it's on to a big slice of Mailbag questions, featuring a deep dive into January and important questions such as which Town player we'd trust to look after our dogs. And we finish with a chat about Kieran McKenna inevitably being linked to the once again vacant job at basket case slumbering giant Manchester United. Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/ Also sponsored by Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/ Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/ You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
In this episode, Dr. Theodore Schurr shares insights from his career researching genetic prehistories, linkages, and identities within transforming geopolitical landscapes of the past as well as contemporary sociopolitical shifts, including post-Soviet Russia and Georgia. Next, Dr. Schurr and hosts Cara and Chris reflect on the evolution of anthropology and genetic research, including breakthrough technologies and advanced field methods, changing bioethics, intentional relationships with communities, and exciting new approaches that are expanding our understanding of variation and genetic-environmental interactions of the past and present. Dr. Theodore (Tad) Schurr is a Professor in the Department of Anthropology and the Director of the Laboratory of Molecular Anthropology at the University of Pennsylvania. For over thirty years, he has investigated the genetic prehistory of Asia and the Americas through studies of mtDNA, Y-chromosome, and autosomal DNA variation in Asian, Siberian, and Native American populations. For these studies, his lab characterized genetic diversity in indigenous populations of Canada, the United States, Mexico, and the Caribbean. His research group is currently exploring the population history of Georgia (Caucasus), Pakistan, Kazakhstan, and Polynesia through collaborative studies in those regions. Other projects have investigated the role of the mtDNA in adaptation, cancer, complex diseases, and metabolism. ------------------------------ Find the papers discussed in this episode: Yardumian, A., Shengelia, R., Chitanava, D., Laliashvili, S., Bitadze, L., Laliashvili, I., ... & Schurr, T. G. (2017). Genetic diversity in Svaneti and its implications for the human settlement of the Highland Caucasus. American journal of physical anthropology, 164(4), 837-852. Schurr, T. G., Shengelia, R., Shamoon-Pour, M., Chitanava, D., Laliashvili, S., Laliashvili, I., ... & Yardumian, A. (2023). Genetic analysis of Mingrelians reveals long-term continuity of populations in Western Georgia (Caucasus). Genome Biology and Evolution, 15(11), evad198. Ancient Lineages: Reconstructing the Genetic History of Svaneti, Northwest Georgia https://www.penn.museum/sites/expedition/ancient-lineages/ ------------------------------ Contact Dr. Schurr: tgschurr@sas.upenn.edu ------------------------------ Contact the Sausage of Science Podcast and the Human Biology Association: Facebook: facebook.com/groups/humanbiologyassociation/, Website: humbio.org, Twitter: @HumBioAssoc Chris Lynn, Co-Host Website: cdlynn.people.ua.edu/, E-mail: cdlynn@ua.edu, Twitter:@Chris_Ly Cara Ocobock, Co-Host Website: sites.nd.edu/cara-ocobock/, Email:cocobock@nd.edu, Twitter:@CaraOcobock Mecca Howe, SoS Co-Producer, HBA Fellow LinkedIn: https://www.linkedin.com/in/mecca-howe/, Email: howemecca@gmail.com
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Mark Heath, Stuart Watson and Alex Jones convene for the first KOA pod of 2026, with Town sitting in the top two for the first time. The boys reflect on the 2-1 win over Oxford, hear from Kieran McKenna and Jens Cajuste and discuss Town's quarter-way dip problem (trademark Stuart Watson). We also look at the bigger picture and consider if Town will now finish in the top two, take a glance at what may happen in the January window and preview the trip to Pompey. And AJ also shares a unique take on the rather lovely red sky at Portman Road during the Oxford game. Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/ Also sponsored by Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/ Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/ You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Ross Halls is joined by Alex Jones to reflect on Ipswich Town's 2-0 win at Coventry City. The boys look back on the game, where Town toppled the Championship leaders at the CBS Arena thanks to goals from Jack Clarke and Wes Burns. There's a special mention for Burns, who scored for the first time since returning from his lengthy ACL injury lay-off. We hear from the winger, who spoke at length about the difficulties he's faced. Then it's onto the stand-out performers and the bigger picture, with the Blues sitting just two points behind second-place Middlesbrough. There's also some chat around the New Year's Day clash against Oxford United, with a winning streak the next big step in Town's bid to secure promotion to the Premier League. Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/ Also sponsored by Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/ Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/ You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Dr. Nirosha J. Murugan is a Tier II Canada Research Chair in Tissue Biophysics as well as Distinguished Research Chair and Assistant Professor in the Department of Health Sciences at Wilfrid Laurier University. Her research focuses on how our bodies, cells, and tissues communicate with each other from the molecular scale all the way up to our organs, physiology, and consciousness. She is interested in the kinds of information that are shared, including light, electromagnetic fields, and electricity, as well as the physics of how the information is transmitted. Her lab develops tools to record biophysical signals and also tools to help reprogram these signals back to a healthy state when something goes wrong in diseases like cancer. Outside the lab, Nirosha loves spending time with her six-year-old daughter and watching her creativity develop. She also practices Olympic recurve archery and relishes the sense of freedom she gets flying as a recreational pilot. She was awarded her B.S. in behavioral neuroscience, her M.S. in biophysics, and her PhD in biomolecular sciences from Laurentian University. Afterwards, she conducted postdoctoral research at the Allen Discovery Center at Tufts University. During that time, she also served as a teaching fellow at Harvard University in the Department of Molecular and Cellular Biology. She served on the faculty at Algoma University before joining the faculty at Wilfrid Laurier University in 2024. Over the course of her early career, Nirosha has received numerous awards and honors including the Early Researcher Award from the Ontario Ministry of Development and Innovation and was the recipient of Rising Awards of Excellence from the Government of Ontario, Young Professional Visionary Award from the Sault Ste Marie Chamber of Commerce and an Optica Foundation Award to develop new optical tools to solve global health challenges. In this interview, Nirosha shares more about her life and science.
Estamos en plenas fiestas navideñas, una época –en teoría-- de amor y paz, un tiempo para la reflexión, la unión familiar, la esperanza y la generosidad. Pero también es un estado mental de alta intensidad, un festín neuroquímico y un desafío adaptativo. Hemos hablado de la neurociencia y el espíritu navideño con Juan Lerma, investigador del CSIC en el Instituto de Neurociencias de Alicante (CSIC/UMH) y miembro de la Real Academia de CienciasAdelina Pastor nos ha informado de una investigación del Centro Andaluz de Biología Molecular y Medicina Regenerativa, que ha demostrado que los compuestos ricos en azufre presentes en el ajo aumentan la esperanza y calidad de vida en ratones. Con testimonios de Alejandro Martín Montalvo, autor sénior del estudio. Con Jesús Zamora hemos hecho un curioso experimento mental: imaginarnos a dos personas adultas, de clase media y de un país occidental, una de ellas que viviese a finales del XIX y que fuese transportada 75 años hacia el futuro; y la otra que viviese en la década de 1970, y a la que de pronto la trajéramos al momento actual. La pregunta sería cuál de las dos se hallaría más sorprendida por los cambios que pudiera observar a su alrededor. Y hablando de viajes en el tiempo, con Javier Ablanque hemos viajado a la batalla de Lepanto para ver cómo se las apañó Cervantes y conocer la física que hay detrás de los ungüentos aplicados en las heridas.Escuchar audio
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Ross Halls caught up with former Ipswich Town forward Daryl Murphy to discuss his time at Portman Road and journey in football in our Kings of Anglia Christmas podcast special. Daryl spoke about a range of memories, including his early life in Ireland, coming over to England, playing in the Premier League with Sunderland and his relationship with Roy Keane. He discusses his multiple loan spells at Town, before joining permanently under Mick McCarthy, his partnership with David McGoldrick, that 27-goal season and overall spell in Suffolk. The Irishman also chats about his transfer request to join Newcastle United, playing for his country, coaching journey, his son now playing and much more. Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/ Also sponsored by Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/ Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/ You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Ross Halls is joined by Stuart Watson to discuss Ipswich Town's 3-1 win over Sheffield Wednesday at Portman Road to climb to third in the Championship table. The duo hear from Kieran McKenna and reflect on the key talking points from the game from striker talk to nervy moments and praise for Cedric Kipre. They also chat about Azor Matusiwa's quality, not being ruthless enough and the Blues closing the gap to second. Then look ahead to festive trips to promotion rivals Millwall and Coventry, before a big Merry Christmas to you all! Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/ Also sponsored by Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/ Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/ You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Renato (Ren) Circi, co-founder of SAVA, a London based MedTech company building a new generation of minimally invasive continuous glucose monitors and molecular wearables.In this episode we rewind to the underground labs at Imperial College London where Ren and his co-founder Raph first immersed themselves in biosensors and began questioning the status quo of health monitoring. Ren explains how their shared obsession with measuring the body more effortlessly led to SAVA's founding and what it really looks like to push through years of scientific failure in order to build a complex medical device platform.We dive into why SAVA manufactures everything in-house, how their micro sensor architecture differs from traditional filament based CGMs and why controlling every layer from chemistry to algorithms is essential if you want to iterate fast on performance. Ren sets out SAVA's long term vision of continuous molecular tracking for everyone, not just people with diabetes, and what could be unlocked once you can monitor many molecules in real time from a single patch.We also talk about regulatory expectations for CGMs, the reality of one way product decisions in medical devices and the difficulty of fundraising for a consumer facing yet highly regulated deep tech company. Ren closes with candid reflections on what he would do differently, how he protects time for family and why working on a problem you truly care about with people you genuinely like is the only way to survive the journey.Timestamps[00:00:21] Origins at Imperial and discovering biosensors[00:01:59] Long horizons, repeated failure and staying in the game[00:03:56] Why SAVA manufactures everything in-house[00:06:46] How SAVA's micro sensor CGM platform actually works[00:09:36] From diabetes to universal molecular health monitoring[00:12:02] Patient experience and CGM adoption in healthcare systems[00:13:43] When CGMs become cheaper than finger-pricks[00:15:15] Misconceptions about CGM and continuous molecular sensing[00:17:21] Why building CGMs is one of the hardest engineering challenges[00:22:54] Fundraising in unconventional deep tech MedTech and advice for foundersConnect with Ren - https://www.linkedin.com/in/circi/Learn more about Sava - https://www.sava.health/Get in touch with Karandeep Badwal - https://www.linkedin.com/in/karandeepbadwal/ Follow Karandeep on YouTube - https://www.youtube.com/@KarandeepBadwalSubscribe to the Podcast
To kick off Season 4, Charles Marmar, MD, explains how precision psychiatry is reshaping the way clinicians and researchers think about diagnosis, treatment selection, and the underlying biology of psychiatric disorders. This conversation is a overview of where the field stands today—including emerging molecular markers, biologically informed subtypes, and new translational approaches inspired by oncology and other precision-based specialties.Dr. Marmar is Chair of Psychiatry at NYU Grossman School of Medicine, and Director of the Center for the Study of Alcohol Use Disorder and Traumatic Stress.In this episode, he outlines current work on:Molecular and genomic signatures that may distinguish patient subtypesClinical trials examining targeted treatments for alcohol use disorderThe development of proxy “brain biopsy” methods such as exosomal analyses and iPSC-derived organoidsHow converging biological data could eventually support more individualized treatment planningThis discussion reflects ongoing efforts at NYU Langone Health to move psychiatry toward a more mechanism-based, biologically grounded model of care, while acknowledging the complexity and early stage of the work. For clinicians, scientists, and trainees, the episode provides a clear snapshot of the major directions shaping precision psychiatry today.CHAPTERS00:00 Introduction: The Challenge in Psychiatry00:34 Meet the Experts01:07 Understanding PTSD: Types and Subtypes04:47 Current Research and Innovations06:19 The Future of Psychiatry: Precision Medicine09:34 Case Study: Personalized Treatment Success11:33 Conclusion: The Path ForwardVisit our website for more Insights on Psychiatry.Watch this episode on YouTubeExecutive Producer: Jon Earle
In this episode, Solomon Moshkevich, president of clinical diagnostics at Natera, discusses how molecular data, MRD testing, and AI-driven tools are transforming clinical decision making across oncology, prenatal care, and chronic kidney disease. He shares insights on evidence generation, system integration, and the opportunities ahead for more personalized, cost-effective care.This episode is sponsored by Natera.
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Mark Heath is joined by Stuart Watson, Alex Jones and - eventually - Ross Halls to bring you our Christmas 2025 special, recorded live with a virtual audience. The boys reflect on the season so far, pick out things they've liked and not liked, and take a look ahead at the January window. We also enjoy plenty of thoughts and questions from the KOA Army, before casting an eye over the Sheffield Wednesday game this weekend and offering our predictions. And we end the show with a big question - where are Town going to finish this season? Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/ Also sponsored by Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/ Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/ You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Send us a textHow seasonal changes in light and dietary unsaturated fats affect circadian rhythms in mammals.Topics Discussed:Evolutionary context of circadian rhythms: All organisms have adapted to Earth's 24-hour day for survival, with internal clocks slightly offset and adjusted by environmental cues.Molecular clock mechanism: Involves a feedback loop where proteins turn on/off genes, lasting ~24 hours, regulated by phosphorylation and degradation for timing precision.Genetic variations in sleep: Families with mutations in clock genes like PER2 cause extreme morning lark behavior, altering protein stability and period length by hours.Light entrainment: Morning light shortens human clocks (average 24.2 hours) to match 24-hour days; seasonal day length changes require gradual adjustments.Food & metabolic links: Seasonal food scarcity/abundance affects clock via glucose and fatty acids competing for protein modifications, as shown in diabetic mouse models.Role of unsaturated fats: Paper finds MUFA/PUFA ratios in diet alter phosphorylation of clock proteins, speeding or slowing adaptation to winter/summer light cycles in mice.Modern environmental impacts: Artificial light extends “daytime” signals, while constant food access erases seasonal patterns, contributing to obesity and diabetes risks.Jet lag & adaptations: Sudden time shifts mimic seasonal experiments; high-sugar/fat intake may phenocopy genetic effects to aid adjustment, though not recommended for health.Practical Takeaways:Expose yourself to morning natural light to help synchronize your internal clock and improve daily energy.Consume main meals during daylight hours and avoid late-night eating to align with natural metabolic rhythms.Limit evening screen time to reduce artificial blue light disrupting sleep onset.Consider varying diet seasonally, favoring diverse, whole foods to mimic natural availability patterns for better health.About the guest: Louis Ptacek, MD is a neurologist and professor at the University of California, San Francisco. He researches inherited neurological diseases and sleep traits, including genetic variations causing extreme early rising.Related Episode:M&M 237: Circadian Biology: Genetics, Behavior, Metabolism, Light, Oxygen & Melatonin | Joseph Takahashi*Not medical advice.Support the showAffiliates: Lumen device to optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts
BUFFALO, NY - December 17, 2025 – A new #research paper was #published in Oncotarget (Volume 16) on December 15, 2025, titled “Machine learning-based survival prediction in colorectal cancer combining clinical and biological features.” In this study, led by Lucas M. Vieira from the University of Brasília and the University of California San Diego, researchers used machine learning to predict survival in patients with colorectal cancer. They built a model by combining biological markers with clinical data. This approach could help improve prognosis and guide treatment strategies for one of the world's most common and deadly cancers. The team analyzed data from over 500 patients, using clinical details such as age, chemotherapy status, and cancer stage, along with molecular features like gene expression and microRNAs. Their goal was to improve how clinicians identify high-risk patients and make outcome predictions more precise. Researchers evaluated three different patient data scenarios using different machine learning techniques. The best-performing was an adaptive boosting model, which achieved 89.58% accuracy. This approach showed that integrating clinical and biological data led to significantly better predictions than using either data type alone. Among the biological markers, the gene E2F8 was consistently influential in all patient groups and is known to play a role in tumor growth. Other important markers included WDR77 and hsa-miR-495-3p, which are also associated with cancer development. Key clinical predictors included cancer stage, patient age, lymph node involvement, and whether chemotherapy was administered. “The proposed method combines biological and clinical features to predict patient survival, using as input data from patients from the United States, available in the TCGA database.” Unlike earlier models that relied on either clinical or molecular data alone, this study demonstrates the added value of combining both. Ensemble methods, which merge multiple learning algorithms, provided more stable and consistent results across all patient groups tested. These research findings could lead to new tools that help clinicians better predict how a patient's disease might progress or respond to treatment. The study also highlights the importance of collecting complete clinical information, such as lifestyle factors, which were missing from the dataset but could enhance future predictions. Overall, the study demonstrated how machine learning can support more accurate and personalized survival predictions in colorectal cancer. It also points to potential future research on markers like E2F8, which may be useful for monitoring or targeted therapy. DOI - https://doi.org/10.18632/oncotarget.28783 Correspondence to - Lucas M. Vieira - lvieira@health.ucsd.edu Abstract video - https://www.youtube.com/watch?v=cy7UL5ZUKuI Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28783 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, colorectal cancer, machine learning, feature selection, non-coding RNAs, genes To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us on social media: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Mark Heath returns for a rare two man pod with Stuart Watson to discuss Ipswich Town's 3-1 defeat at Leicester City. The duo hear from Kieran McKenna, reflect on Town's underwhelming display and ponder the goals conceded. Then it's onto a bit of group therapy as we look at the bigger picture, share what we think about Town so far this season and debate whether our glasses are half full or half empty heading into the Christmas crunch. Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/ Also sponsored by Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/ Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/ You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
I've discovered a potent tool that comes down to foundational health. Helping our body on a cellular level with the seemingly most 'basic' of tasks, but ones that are fundamental to our overall health. Molecular hydrogen infused 'water' helps things like dehydration, inflammation & oxidative stress simultaneouly, allowing our cells to come back online & function optimally. Like a conductor in an orchestra, who creates sweet harmony & music through their guidance & talent, molecular hydrogen acts like a 'master conductor' in the body, scanning for cells that are offline, flat, out of tune etc & upregulating them or downregulating them in order to restore flow & harmony. It's a feeling that you cannot deny! You will experience a shift & this is a powerful solution I feel called to share with the world. https://spiritinform.lumivitae.com/en/ https://www.karenmaloney.com/ @karenmaloney_
Molecular biologist Judith Frydman studies the nuances of protein folding and how defects in the process lead to neurodegenerative diseases. Her team studies protein folding in human cells and in model organisms, like yeast and worms, to understand the molecular events that precipitate harmful protein defects in humans. In one example, Frydman's team explored how aging affects the creation and the quality of proteins in the brain, leading to cognitive problems. She is now looking to develop therapies – someday perhaps leading to cures – to debilitating diseases such as Alzheimer's, Parkinson's, Huntington's, ALS, and others. The power of science gives her true hope in these important pursuits, Frydman tells host Russ Altman in this episode of Stanford Engineering's The Future of Everything podcast.Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your question. You can send questions to thefutureofeverything@stanford.edu.Episode Reference Links:Stanford Profile: Judith FrydmanConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / FacebookChapters:(00:00:00) IntroductionRuss Altman introduces guest Judith Frydman, a professor of biology and genetics at Stanford University.(00:04:00) Linking Protein Folding to AgingHow aging disrupts protein-folding machinery across many organisms.(00:07:16) Universal Aging PatternsThe similar age-related protein-folding defects found across organisms(00:09:27) Studying Killifish AgeingResearch on the African killifish as a rapid-aging model organism.(00:13:05) Ribosome Function DeclinesHow aging causes ribosomes to stall and collide, creating faulty proteins.(00:15:31) Aging Across SpeciesThe potential factors causing alternate aging rates in different species.(20:11) What Fails Inside Aging CellsThe cellular components that are leading to bad protein creation.(00:24:04) Therapeutic ApproachesPotential interventions to combat cellular and neurological degeneration.(00:25:12) Gene vs. Small-Molecule TreatmentsHow some interventions may be better suited for certain diseases.(00:27:47) Ribosome Drug PotentialWhy ribosomes and translation factors are viable drug targets.(00:28:56) Next Steps in Aging ResearchUsing human skin fibroblasts to study human aging mechanisms.(00:31:46) Future In a MinuteRapid-fire Q&A: scientific progress, young researchers, and archeology.(00:33:54) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
01. Seventhrun - Ashes To Light 02. Feed the Fire - Let Go 03. Dapreme, ADUKEN, Licia - Bleed For You 04. Wilkinson, iiola - Back Up 05. T & Sugah - Pam Pam 06. Tantrum Desire - Killerz 07. Used, Lily Denning - Control 08. Solomon France - Down Bad 09. Document One - Spin Doctor 10. TURNO, Clarkey, Kay Rico Light Up The Rave 11. Kanine, Arcando, HEIGHTS - Lost Tonight 12. Axel Boy, Afroditetoolively - Nowhere to Hide (blkout. Remix) 13. Misanthrop - Deep Down Raw 14. Midnight CVLT, Ric Waves - Echo Protocol 15. oneBYone & Oneder - Boom Bang 16. Double Medley, Subminderz - Get It Straight 17. Minimalist - Tribe 18. Prolix - Space & Time 19. Gancher_&_Ruin - Моя_Печаль_Vocal_Mix 20. MIDNIGHT CVLT x PROLIX - Shadows In The Dark 21. Magnetude feat. The Velvet Effect - Silhouette 22. MNDSCP - Raw 23. MIDNIGHT CVLT - Back Home 24. Pythius - All You Need 25. Exit4 - Red vip 26. Inerpois, Backup - Brain Error 27. Absu_NTQL - Lifeform 28. Frosta - No Mercy 29. Kvostax&Unquiet&Exit4 - F**ing Daiting 30. [BORDERS], Puzzle - Against All Odds 31. Break - All You Gotta Do 32. Dunk - Dark Clouds 33. OODINI - Jazz Anthem 34. Trail, Objectiv - Pitch Dark (Objectiv Remix) 35. Keeno - Follow 36. Irah, Goddard. - Eye Of The Storm 37. Basstripper - Ready For It 38. JFlux - All Points Squared 39. 2Whales - Ryadom 40. INDIKINO, Sovsem dikaya - More Dyshit 41. Ozma, Женя Винд - Орёл 42. Fakear - waking up is better with you (Remix, extended) 43. DJ Science - One Love, Dubwise 44. AnnGree - What I Had To Do 45. Loud.Drop - Metal Chicken 46. Octavate - The Walls 47. Molecular, En:vy - Speed Racer 48. Furniss - End of time 49. GGrossy - Alarming Surge 50. Maurizzle, Justin Hoffmann Pistolero 51. Pruf - Ice 52. Magenta & GR4HM - Lock It Off 53. DOWNCAST - Bad Boy (Extended Mix) 54. Subrix - Dubplate 88 55. FooR, CLSM - Hardcore Vibes 56. Dem MC - The Roots of Existence 57. Mr Quest - Break The Script 58. Discord - Two Sides To This Story 59. Doom Poets, Technical Itch - THROUGH THE SEAS 60. Grey Man - Believe 61. Glitch City & DJSS ft Blaxx & Maddy V - WHY Contagion Remix 62. Uneven - The Unknown 63. Ahmad - Burn 64. Fetus - Half Half (Amor Satyr Remix) 65. Spirit - International (London Mix) 66. Heavyweight - Holy Grail 67. Hyperfocus - If You Know 68. Sonic Art x Kayaman - Untitled_Jam (Dissident Remix) 69. FRACTURE, NEPTUNE - Erase Everything 70. Primal Tribes - Whispering Silence Crawls On Me 71. GIROSKOP - Darkway 72. DRS, Zar - Handle Us 73. Kleu, Leanne Louise - Complicated 74. Majestic, Jungle 70 - Creeping In The Dark (Danny Byrd Extended Remix) 75. 30Hz - Dark Matter 76. Royalston feat. Jaynee - Sour 77. Telomic & Sam M - Holding On 78. Spectrum - Altered Perception 79. Calibre - Don't Feel For Me 80. Jonathan Baker Silver 81. Promenade - Always You 82. Lsb - PCT
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Ross Halls is joined by Stuart Watson to reflect on Ipswich Town's 1-0 win against Stoke City. The boys hear from Kieran McKenna after the Blues made it back-to-back home wins, thanks to Jaden Philogene scoring his seventh goal of the season. They chat about his exquisite curling finish hear from the player on where he would rank this goal, plus talk about his form this season. There's a conversation around standing strong against the Potters, Ivan Azon's big chance and a look back at the big week for the club. Then it's onto the trip to Leicester City, while we announce the news that KOA Live 3 has been postponed. Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/ Also sponsored by Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/ Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/ You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Taboo to Truth: Unapologetic Conversations About Sexuality in Midlife
In this episode of Taboo To Truth, I sit down with surrogate partner and intimacy coach Brian Gibney to talk about what happens when touch, sex, and therapy meet. We walk through the origins of surrogate partner therapy, how it supports traditional talk therapy, and why it sits inside the world of sex work while still holding clear ethical boundaries. Brianan explains who seeks out this work, what sessions look like in real life, how attachment and feelings show up, and why sex itself often turns out to be a symptom rather than the real issue. We also talk about non-monogamy, money, how to vet an ethical surrogate partner, and Brian's very expansive definition of sex.Timestamps:In This Episode:00:00 - What if sex was part of your therapy01:08 - What surrogate partner therapy is and why talk therapy hits a limit03:42 - Masters and Johnson and the birth of surrogate partners06:05 - Sex work, the “whorarchy”, and where surrogates sit in it09:18 - How surrogate partner therapy differs from full service intimacy work11:52 - The therapeutic triad: client, therapist, surrogate13:40 - Who seeks this work: trauma, pain, cancer, disability, shame17:05 - First sessions, nerves, and why the work starts with “hello”19:40 - When clients expect something more and run the “checklist” for access22:15 - Entitlement, hard conversations, and repeating old patterns24:05 - Attachment, feelings, and why the “box” stays small26:10 - Brian's non monogamy and protecting his own relationships28:30 - Boundaries to this work30:35 - How to vet a legitimate surrogate partner and red flags32:10 - Brian's expansive definition of sex and why PIV is not the gold standard34:00 - Final thoughtsWant a deeper look? Watch the full episode on YouTube for a more visual experience of today's discussion. This episode is best enjoyed on video—don't miss out!Karen Bigman, a Sexual Health Alliance Certified Sex Educator, Life, and Menopause Coach, tackles the often-taboo subject of sexuality with a straightforward and candid approach. We explore the intricacies of sex during perimenopause, post-menopause, and andropause, offering insights and support for all those experiencing these transformative phases.This podcast is not intended to give medical advice. Karen Bigman is not a medical professional. For any medical questions or issues, please visit your licensed medical provider.Looking for some fresh perspective on sex in midlife? You can find me here:Email: karen@taboototruth.comWebsite: https://www.taboototruth.com/Instagram: https://www.instagram.com/taboototruthYouTube: https://www.youtube.com/@taboototruthpodcastAbout the Guest:Over the course of his life, Brian has worn many hats: research scientist (BA, Molecular biology; Masters, Microbiology), teacher, professional artist, performer, and parent. The common thread that has run through all of those vocations has been his joy in learning, discovery, and improvement. In parallel with his professional life, He has also been keenly interested in interpersonal interactions, intimacy, and authenticity. These two facets have merged in his practice as a Surrogate Partner. He...
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Ross Halls is joined by Alex Jones to reflect on Ipswich Town's 3-0 win against Coventry City. The boys look back at the game, where Sindre Walle Egeli, George Hirst and Ivan Azon were all on the scoresheet to secure a convincing victory against the Championship leaders. But should Hirst have been on the pitch? There's talk about his lucky red card escape, stand out performers from the match, and whether this will finally be the moment for the Blues to kick on after previous false dawns. There's also chat around Stoke City and the FA Cup draw, as well as an illness update after a week on the road. Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/ Also sponsored by Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/ Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/ You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
We dive into Will's recent research assessing the effects and prevalence of Lymphoproliferative Disease Virus (LPDV) in wild turkeys in Alabama. Resources: Alger, K., et al. (2017). Risk factors for and spatial distribution of lymphoproliferative disease virus (LPDV) in wild turkeys (Meleagris gallopavo) in New York State, USA. Journal of wildlife diseases, 53(3), 499-508. Goodwin, C. C., et al. (2024). Experimental infection of domestic turkeys with lymphoproliferative disease virus of North American origin. Veterinary Pathology. Shea, S. A. (2021). Retroviral infection dynamics in Maine's wild turkeys. The University of Maine. Thomas, J. M., et al. (2015). Molecular surveillance for lymphoproliferative disease virus in wild turkeys (Meleagris gallopavo) from the eastern United States. PLoS One, 10(4), e0122644. Ostrander, K. N., et al. (2025). Histomonosis and Lymphoproliferative Disease Virus in Male Wild Turkeys (Meleagris gallopavo) in Alabama, USA. Journal of Wildlife Diseases. Our lab is primarily funded by donations. If you would like to help support our work, please donate here: http://UFgive.to/UFGameLab We've launched a comprehensive online wild turkey course featuring experts across multiple institutions that specialize in habitat management and population management for wild turkeys. Earn up to 20.5 CFE hours! Enroll Now! Dr. Marcus Lashley @DrDisturbance, Publications Dr. Will Gulsby @dr_will_gulsby, Publications Turkeys for Tomorrow @turkeysfortomorrow UF Game Lab @ufgamelab, YouTube Donate to our wild turkey research: UF Turkey Donation Fund , Auburn Turkey Donation Fund Want to help wild turkey conservation? Please take our quick survey to take part in our research! Do you have a topic you'd like us to cover? Leave us a review or send us an email at wildturkeyscience@gmail.com! Watch these podcasts on YouTube Please help us by taking our (quick) listener survey - Thank you! Check out the DrDisturbance YouTube channel! DrDisturbance YouTube Want to help support the podcast? Our friends at Grounded Brand have an option to donate directly to Wild Turkey Science at checkout. Thank you in advance for your support! Leave a podcast rating for a chance to win free gear! This podcast is made possible by Turkeys for Tomorrow, a grassroots organization dedicated to the wild turkey. To learn more about TFT, go to turkeysfortomorrow.org. Music by Artlist.io Produced & edited by Charlotte Nowak