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Classification and Dating of Meteorites 3. Cosmochemist Greg Brennecka details meteorite classifications, emphasizing chondrites—primitive, unmelted samples representing the early molecular cloud and serving as the "baby book" of the solar system—whereas acondrites have been melted and often come from differentiated or disrupted planets. Brennecka specializes in Calcium Aluminum-rich Inclusions (CAIs) found within chondrites, which are used as a precise clock to date the solar system at 4.567 billion years old, and another stunning type is the pallasite, believed to originate from the core-mantle boundary of a planet and featuring spectacular olivine crystals in an iron matrix. Modern cosmochemistry relies on techniques like solution chemistry, where samples are dissolved in acid to precisely measure isotopes and elements. 1958
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Ross Halls is joined by Stuart Watson and Alex Jones to reflect on Ipswich Town's 4-1 win at Swansea City. AJ takes over hosting duties to grill Ross and Stu about the match, where goals from Jack Clarke and Ivan Azon - coupled with a brace from ex-Blue Cameron Burgess - handed Kieran McKenna's side three points. There's a chat around the standout performers and what the result means going forward, with the Blues heading into the November international break sitting seventh in the Championship. Then it's onto the campaign as a whole, with plenty to discuss surrounding AJ's birthday celebrations and the upcoming KOA Live 3. Buy KOA Live 3 tickets: https://dice.fm/event/53x788-kings-of-anglia-20th-dec-the-baths-ipswich-tickets Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/ Introducing our new sponsors at Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/ Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/ You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
In his weekly clinical update, Dr. Griffin with Vincent Racaniello discusses the link between in utero SARS-CoV-2 infection and poor neurodevelopment outcomes, the use of an mRNA vaccine as an anti-cancer therapy, why one should receive the HPV vaccine, asymptomatic H5N1 isolations in humans, and H5N1 on turkey farms, before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, how two vaccinated physicians became infected with measles, effective of COVID-19 vaccine for children, where to find PEMGARDA, how to access and pay for Paxlovid, can you be retreated with Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, how a specific antibody type may associate with recovery from long COVID, if use of a probiotic is helpful to treat mild COVID-19, if vaccination helps prevent long in adolescents and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Neurodevelopmental Outcomes of 3-Year-Old Children Exposed to Maternal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Utero (Obstetrics & Gynecology) SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade (Nature) TWiV 1267: A cancer vaccine and an mpox treatment (microbeTV: TWiV1267) Cancers Caused by HPV (CDC: Human papillomavirus (HPV)) Circulating tumor human papillomavirus DNA whole genome sequencing enables human papillomavirus-associated oropharynx cancer early detection (Journal of National Cancer Institute) Impact of Vaccinating Adult Women Who Are HPV-Positive or with Confirmed Cervical SIL with the 9-Valent Vaccine (Viruses) ACIP Shared Clinical Decision-Making Recommendations (CDC: Advisory Committee on Immunization Practices (ACIP)) HPV Vaccination Recommendation (CDC: Vaccines & Immunizations) Asymptomatic Human Infections With Avian Influenza A(H5N1) Virus Confirmed by Molecular and Serologic Testing (JAMA: OPEN Network) Review: Human H5N1 avian flu cases can be asymptomatic, and the virus likely spreads among people (CIDRAP) Avian flu strikes turkey farms in Dakotas, large egg facility in California (CIDRAP) Another Doctor at Ichilov Contracts Measles After Treating Unvaccinated Child (gov.il) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Measles (CDC Measles (Rubeola)) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) ACIP Recommendations Summary (CDC: Influenza) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Vascular and inflammatory diseases after COVID-19 infection and vaccination in children and young people in England (LANCET: Child & Adolescent Health) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Real-World Effectiveness of Nirmatrelvir-Ritonavir in Preventing Coronavirus Disease 2019–Associated Hospitalization (CID) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID SARS-CoV-2 spike-specific IgG4 class switching associates with clinical recovery in Long COVID (Journal of Infection) Efficacy of Lactococcus lactis Strain Plasma in Patients with Mild COVID-19 (Infectious Diseases and Therapy) Preventive effect of vaccination on long COVID in adolescents with SARS-CoV-2 infection (Vaccine) Reaching out to US house representative Letters read on TWiV 1268 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.
Holaaa :)En este episodio tengo el placer de conversar con el Dr. Juan Viña, médico, Catedrático de Bioquímica y Biología Molecular en la Universidad de Valencia, investigador y además mi padre.Nos contará cual es la ciencia y explicación bioquímica real detrás de la dieta cetogénica, el ayuno y la cetosis, para entender qué ocurre realmente en nuestro cuerpo cuando cambiamos de usar la glucosa ( azúzar) como fuente de energía a los cuerpos cetónicos. Hablamos de temas clave como:Qué son los cuerpos cetónicos y por qué nuestro organismo los produce.La diferencia entre estar en cetosis y seguir una dieta keto estricta.Los beneficios reales de la cetosis, más allá de la pérdida de peso, incluyendo su uso en enfermedades como la epilepsia o el deterioro cognitivo.Qué rutas metabólicas claves para la longevidad se activan durante los periodos de ayuno donde se elevan los cuerpos cetónicosEn qué casos puede ser peligrosa y qué personas deberían tener precaución.Y, por último, la verdad sobre los suplementos de cetonas exógenas: ¿sirven o son solo marketing? Espero que tras compartir con nosotros está conversación puedas entender todavía mejor cómo funciona tu metabolismo, cuándo tiene sentido entrar en cetosis y qué riesgos o beneficios reales hay detrás de la dieta keto y el ayuno intermitente.Para mas información ya sabéis que me tenéis en mi instagram @isabelvina dónde te comparto contenido diario Mi TikTok @isabelvinabasEn mi canal de YouTube Canal YoutubeY los suplementos formulados por mi en mi web Mi web
Matters Microbial #115: Suiting Up Against Bacterial Predators! November 6, 2025 Today Dr. Hannah Ledvina, Assistant Professor in the Molecular, Cellular, and Developmental Biology Department at the University of Michigan joins the #QualityQuorum to discuss how bacteria can protect themselves against predators in unusual ways . . . including a type of armor! Host: Mark O. Martin Guest: Hannah Ledvina Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode The "Giant Microbes" website. A prompt for my course: an article on "Animals in a Microbial World," with so many interesting examples. Here is a summary for novice #Micronauts. A prompt for my course: an article by the late, great Lynn Margulis on the nature of kefir grains and the definition of multicellularity and the organism. A prompt for my course: an article on hyperpolyploidy in bacteria. An explanation of "genomic islands." A link to a previous guest of #MattersMicrobial, Dr. Laura Williams, discussing Bdellovibrio and undergraduate based research. An overview of predatory bacteria. Here is a more recent overview. An overview of the predator Myxococcus. A wonderful video showing the predatory process of Myxococcus. A fine review of the predator Bdellovibrio. A video of the life cycle of Bdellovibrio. Some work by Dr. Koval and colleagues suggesting that aspects of the outer cell wall is not involved with resistance to Bdellovibrio. Recent VERY exciting work suggesting that there is indeed a receptor on bacteria that Bdellovibrio can recognize. Here is a short summary of that work. Could Bdellovibrio become a "living antibiotic"? A reminder from Drs. Kolter and Losick that bacteria in the laboratory can be quite different from their relatives in nature. The article under discussion on this podcast by Dr. Ledvina and colleagues. Here is an editorial summary on the article. An article on curli proteins in bacteria. An article on amyloid like proteins in bacteria. A video by Dr. Ledvina on the research interests of her group. Thoughts on an "immune system" for bacteria. Dr. Ledvina's faculty website. Dr. Ledvina's research group website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
The most popular wrestling show in five galaxies is in danger of being shut down, unless the wrestlers jump into action to save it. Genre: Science Fiction, Fantasy Excerpt:"Sentient entities of the cosmos!" the announcer spoke, her voice booming through the arena that floated in free space. "Welcome…to GROWL! The audience cheered, waving their flags, waving their extremities, and shouting the names of their favored fighters. The announcer paused until they settled. "Our first contender on tonight's mind-blasting roster, is also our first human ever. Hailing from Earth, wielding the powers of biological science, I give you….Molecular!" What story or stories am I revisiting in this episode? Each Season 8 episode is a standalone story, but it's connected to or inspired by a previous story through a character, a place, an object, a concept, a continuation of events (ahem, sequel), and so on. This story has multiple influences, from a show I watched in childhood to a writing prompt to a previous episode featuring non-human arena battles,"Great Persidain" MY FIRST BOOK (yay)Ever wonder how I've gotten all these hundreds of stories written? I have a method. And I talk all about it in my book called Fictioneer's Field Guide: A Game Plan for Writing Short Stories. It's now available from Amazon as an eBook, paperback, and hardcover. You can also get there from my Store page: STORYFEATHER STORE The Store page also has sign-up forms for my two email newsletters: Storyfeather Gazette (if you'd like to keep up with the fiction I create) Fictioneer's Field Guide (if you'd like writing tips and guidance from me) Choose what you want. (Either way, you're choosing high jinks.) MERCH!Interested in merch, like mugs and notebooks, featuring my artwork? Please visit my Store page for info on where you can buy: STORYFEATHER STORE CREDITSStory: "Galactic Ring of Wrestling Ladies" Copyright © 2021 by Nila L. Patel Narration, Episode Art, Editing, and Production: Nila L. Patel Music: "Casual Arcade Track #2 (looped)" by ANDREW SITKOV (Intro & Outro) "Casual Arcade Track #3 (looped)" by ANDREW SITKOV (Outro) "Abstract Vision #5" by ANDREW SITKOV (Outro) Music by ANDREW SITKOV (MuzStation Game Music) "Casual Arcade Track #3 (looped)" "Casual Arcade Track #1 (looped)" "Casual Arcade Track #1 Version 2 (looped)" "Motivation (looped)" "Drive With Me (looped)" "Battle Theme 5" "Epic Drums" "Hidden Threat (looped)" "Reinforcement (looped)" "Prepare for Battle (looped)" "Two Sides (looped)" "Never Back Donw (looped)" "Heart of Warrior NEW (Lyric Part Version 1)" "The Superiority (looped)" Music by NICHOLAS JEUDY (Dark Fantasy Studio) "Under the mask" "Connecting dots" "Negociation" "Genetic Marker" "Doubts" "Particle voyager" All these tracks are part of a music and sound effects bundles I purchased from Humble Bundle and sourced from GameDev Market. Music by Nicholas Jeudy and Andrew Sitkov is licensed from GameDev Market Sound effects from AudioJungle, GameDevMarket, and Soundly (through Hindenburg) Vocal effects created with Audacity Changes made to the musical tracks? Just cropping of some to align with my narration. Find more music by Nicholas Jeudy and Andrew Sitkov at gamedevmarket.net Find more stories by Nila at storyfeather.com Episode Art Description: Digital drawing. Five figures arrayed in flanking formation. At center is a human woman facing forward from waist up. She holds her hands before her, facing each other. A glowing ball of light is suspended between her fingers. Along the forearm part of her left armband, a lightning bolt glows. She wears color-blocked exercise clothes. A humanoid lizard sits to her right and behind, raising her right arm as if in greeting. She wears a scarf around her neck, and a breastplate displaying circuitry. To the lizard's right and behind is a giant seagull, wings outspread, head raised, and beak open, blasting out a ray of swirling circles. To the human woman's left, a toad springs up and out. To the toad's left and behind, a unicorn with a rainbow mane rears up, her horn blasting forth a ribbon of light. Watermark of "Storyfeather" appears along the edge of the seagull's wings. The rectangular image is made square with top and bottom borders with streaks of colors matching the rainbow hues of the main image.
On this episode of Translating Proteomics, Parag speaks with Professor Jennifer Geddes-McAlister from the University of Guelph. Professor Geddes-McAlister is an expert at using proteomics to study host-microbe interactions from a systems biology perspective. Her exciting work spans studies of pathogenic fungi all the way to engineering plants to produce pharmaceutics (so-called “molecular pharming"). On top of all that, Professor Geddes-McAlister also founded “Moms in Proteomics” to support and encourage an intentional focus on the inherently unique physical, emotional, and biological commitments of Mothers, and the ensuing balance required to excel within the diverse STEM fields encompassing Mass-Spectrometry-based proteomics. Dive into this episode to:Learn why it's critical to study hosts, pathogens, and molecular pharming from a systems point of viewDiscover what Professor Geddes-McAlister is excited about for the upcoming Human Proteome Organization (HUPO) conferenceFind out what “Moms in Proteomics” has planned for HUPOChapters00:00 - Intro01:39 - Professor Geddes-McAlister's initial interest in host-microbe interactions06:13 - Why it's important to study host-microbe interactions08:10 - Pathogens vs helpful microbes10:06 - Thinking about microbes through the lens of "One Health" 14:34 - Why Professor Geddes-McAlister works primarily in proteomics as opposed to other omes19:44 - Professor Geddes-McAlister's favorite thing that she's learned from the proteome and couldn't learn from the other omes24:56 - Molecular pharming29:35 - The need for accessibility in proteomics34:09 - The need for all-in-one workflows in proteomics36:08 - HUPO 202539:56 - Moms in Proteomics42:36 - The future of proteomics43:59 - OutroResourcesGeddes et al., 2015. Secretome profiling of Cryptococcus neoformans reveals regulation of a subset of virulence-associated proteins and potential biomarkers by protein kinase Ahttps://pubmed.ncbi.nlm.nih.gov/26453029/Some of Professor Geddes-McAlister's early work using proteomics to study pathogenic fungiPrudhomme et al., 2024. Bacterial growth-mediated systems remodelling of Nicotiana benthamiana defines unique signatures of target protein production in molecular pharminghttps://onlinelibrary.wiley.com/doi/10.1111/pbi.14342Researchers from Professor Geddes-McAlister's lab use multiomic techniques to discover factors impacting the production of a pharmaceutical in an engineered plantWoods et al., 2023. A One Health approach to overcoming fungal disease and antifungal resistancehttps://wires.onlinelibrary.wiley.com/doi/full/10.1002/wsbm.1610Review on the importance of incorporating “One Health” principals into efforts to fight pathogenic fungiMoms in Proteomics websitehttps://momsinproteomics.caLearn all about the Moms in Proteomics initiative and its international community
In this episode, Dr Rachel Grisham and Dr Kathleen Moore discuss newly approved treatments for low-grade serous ovarian cancer (LGSOC) and how recent research has transformed the therapeutic landscape for these patients, including:Molecular distinctions between low-grade and high-grade serous ovarian cancer that can guide therapy selectionThe recently approved targeted therapy combination regimen of avutometinib and defactinib for KRAS-mutant LGSOC (RAMP 201)Promising future directions for patients with LGSOC based on ongoing studies such as RAMP 301 and CHAMELEON Presenters:Rachel Grisham, MDSection Head of Ovarian CancerMemorial Sloan Kettering Cancer CenterDirector Gynecologic Medical Oncology, MSKCC WestchesterNew York, New YorkKathleen N. Moore, MD, MS, FASCODeputy Director and Cancer Therapeutics Co-LeadStephenson Cancer Center at the University of OklahomaProfessorDepartment of OB/GynASCO BODOklahoma City, Oklahoma Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Ross Halls is joined by Alex Jones to discuss Ipswich Town's 1-1 draw against Watford. The boys look back at last night's game, where the Blues were pegged back after some poor defending. Jaden Philogene's low strike levelled things up, but there was no way through to find a winner at Portman Road. Then it's onto a chat about Ivan Azon's woes in front of goal, stand-out players against the Hornets and the dramatic on-field spat between Philogene and team-mate Azor Matusiwa. There's also talk about the upcoming trip to Swansea City and KOA Live 3, while AJ has a panic about the recording button. Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/ Introducing our new sponsors at Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/ Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/ You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Dr. Heidi Tissenbaum, a molecular geneticist at UMass Chan Medical School, joins Buck Joffrey to explore what C. elegans worms have revealed about the biology of aging. She explains how these simple organisms helped uncover key longevity pathways—like insulin/IGF-1 signaling and sirtuins—that also exist in humans. The conversation dives into the balance between stress and resilience, the role of IGF-1 in muscle health and lifespan, and why she believes true longevity breakthroughs will require understanding how the body's systems communicate as a whole. Learn more about Dr. Heidi Tissenbaum: https://profiles.umassmed.edu/display/133231 - Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://ru01tne2.pages.infusionsoft.net/?affiliate=0 Book a FREE longevity coaching consultation with Dr. Buck Joffrey: https://coaching.longevityroadmap.com
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Stuart Watson, Ross Halls and Mark Heath are back to discuss all things Ipswich Town after their 4-1 win at QPR. The boys reflect on the game and hear from Kieran McKenna and two-goal star man George Hirst. There's also chat about the other brace-bagger Marcelino Nunez, plus Sindre Walle Egeli, Jack Taylor and Cedric Kipre. Then it's onto tomorrow night's home clash with Watford, how many changes we think McKenna will make and our predictions for the game. Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/ Introducing our new sponsors at Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/ Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/ You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Una de las joyas de la corona cientifica en Espana cumple 50 anos y lo celebramos con dos de sus cabezas pensantes, Paola Bovolenta, directora del Centro de Biologia Molecular Severo y Luis Blanco, Investigador Principal del Centro de Biologia Molecular Severo Ochoa.
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Alex Jones, Ross Halls and Mark Heath are back to discuss all things Ipswich Town ahead of this weekend's trip to QPR. We start with the elephant in the room - Kieran McKenna's link with the vacant job at Celtic. We hear what he had to say at yesterday's presser, plus debate why he might or might not be interested - and finish with our verdict as to whether he'll go. Then it's onto injury news, why Town are so bad away from home, and a look at QPR. We finish by disagreeing about who will start tomorrow and offering our predictions. Plus Alex shares a story about the time he and his friends got a chum onto the list of favourites to become the new Notts County boss. Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/ Introducing our new sponsors at Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/ Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/ You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Featuring an interview from Dr John Strickler, including the following topics: Prognostic value of molecular residual disease (MRD) as detected by circulating tumor DNA (ctDNA) and optimal incorporation of MRD assays into the care of patients with colorectal cancer (0:00) Potential use of MRD assays for patients with microsatellite instability (MSI)-high localized colorectal cancer or those with delayed progression or metastatic disease (16:09) Tumor-informed MRD assays under clinical development (20:36) Predictive role of ctDNA in Stage III colon cancer treated with celecoxib; effect of low-dose aspirin on response to celecoxib in patients with PI3K pathway alterations (24:19) Case: A man in his late 50s with resected Stage IIA colon cancer (30:06) Case: A woman in her late 40s with Lynch syndrome and MSI-H colon cancer with a solitary, small hepatic metastasis (34:57) MRD as a future clinical trial endpoint for solid tumors; increasing incidence of colorectal cancer in younger people (40:24) Antibody-drug conjugates in the treatment of colorectal cancer (45:13) Perspectives on promising areas of clinical research in colorectal cancer (48:23) CME information and select publications
A screencast from Chapter 5 in CH 221 entitled “Valence Bond and Molecular Orbital Theory”
A screencast from Chapter 5 in CH 221 entitled “An Introduction to Molecular Orbital Theory”
Dr John Strickler from Duke University in Durham, North Carolina, discusses the measurement of molecular residual disease and its current and potential role in colorectal cancer risk assessment, surveillance and treatment decision-making. CME information and select publications here.
Dr John Strickler from Duke University in Durham, North Carolina, discusses the measurement of molecular residual disease and its current and potential role in colorectal cancer risk assessment, surveillance and treatment decision-making. CME information and select publications here.
Dr John Strickler from Duke University in Durham, North Carolina, discusses the measurement of molecular residual disease and its current and potential role in colorectal cancer risk assessment, surveillance and treatment decision-making. CME information and select publications here.
Federico e Isabel González entrevistan a Pablo Castán, doctor en biología molecular.
Featuring a slide presentation and related discussion from Dr John Strickler, including the following topics: Defining molecular residual disease (MRD); tumor-informed and tumor-naïve methods for assessing (0:00) GALAXY and BESPOKE CRC studies of a tumor-informed MRD assay to identify patients with localized colorectal cancer who have an increased risk of recurrence and those who are likely to benefit from adjuvant chemotherapy (6:56) Sustained circulating tumor DNA (ctDNA) clearance and disease-free survival outcomes for patients with localized colorectal cancer (13:21) DYNAMIC study of a ctDNA-guided approach to adjuvant chemotherapy for patients with Stage II colorectal cancer (16:17) ctDNA positivity and radiographic evidence of colorectal cancer (18:48) ctDNA-guided approaches to escalating or de-escalating adjuvant chemotherapy for patients with localized colorectal cancer (21:24) Predictive role of ctDNA assay results in Stage III colon cancer treated with celecoxib; low-dose aspirin for patients with Stage II to III colorectal cancer with a PI3K pathway alteration (26:02) CME information and select publications
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Ross Halls is joined by Steve Lewis and Jon Watson to discuss all things Ipswich Town. The boys start with their one word review of the West Brom win, the atmosphere at Portman Road and feelings on the season so far. Then it's on to the reports on Kieran McKenna links with Celtic and Sam Szmodics latest injury set-back. They also look ahead to the trip to QPR and latest edition of The Strike! Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/ Introducing our new sponsors at Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/ Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/ You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Today's episode is one I've really been looking forward to because we're diving into something that's transforming the way we think about mental health treatment: low-dose ketamine therapy. My guest, Dr. Sharon Niv, is the co-founder of Joyous, a public benefit company helping make this kind of care more accessible and affordable than ever before. Sharon brings a fascinating background in cognitive psychology, meditation, and technology, and she's helping bridge the gap between neuroscience and therapy in a way that's incredibly gentle, safe, and empowering for both clients and clinicians. We'll talk about what makes psycholytic, or low-dose, ketamine different from traditional psychedelic experiences, how it can enhance the therapeutic process, and how you, as a therapist, can get trained to integrate it into your own work. This is one of those conversations that opens your mind to what's possible in therapy, so let's jump in. Resources Mentioned In This Episode Use the promo code "GORDON" to get 2 months of Therapy Notes free Consulting with Gordon The PsychCraft Network Profit First for Therapists Workbook Meet Sharon Niv, Ph.D. Dr. Sharon Niv is a cognitive psychologist and co-founder of Joyous Team, a Public Benefit Corporation dedicated to making evidence-based mental health treatments accessible and affordable. Her work bridges the worlds of neuroscience, technology, and therapy with a focus on how scalable, data-driven approaches can enhance emotional well-being. Dr. Niv earned her Ph.D. in Brain and Cognitive Science from the University of Southern California, where she conducted research on EEG biomarkers, neurofeedback, and the neural underpinnings of mood and behavior. She also holds a B.A. in Molecular and Cellular Biology from UC Berkeley and an M.A. in Clinical and Cognitive Psychology from USC. Before founding Joyous, Sharon worked on developing virtual-reality interventions for chronic pain and neurofeedback programs designed to help people improve emotional regulation and resilience. A long-time meditation practitioner, she combines scientific rigor with a deep understanding of mindfulness and experiential learning. Through Joyous, Sharon and her team are pioneering low-dose (psycholytic) ketamine therapy, creating safer, more sustainable pathways for individuals and therapists to experience healing and insight. Her mission is to empower both clinicians and clients with practical tools that promote neuroplasticity, compassion, and mental clarity. The Power of Therapy + Joyous Joyous Substack LinkedIn
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Ross Halls, Alex Jones and Mark Heath are back to discuss all things Ipswich Town after the Blues' important 1-0 win over West Brom on Saturday. The boys discuss Kieran McKenna's ‘difficult atmosphere' comments - and play the audio - plus debate the non-penalty on Philogene and hear from match-winner Jack Clarke. We chat about Marcelino Nunez as the 10 too, argue about who should start next to Dara O'Shea and praise Jack Taylor's surprising display in the engine room. Then it's on to Fabio Wardley's remarkable win over ex-world champion Joseph Parker at the O2 Arena, plus Rossi gives us some insight into the red hot U21s side who are excelling in PL2. Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/ Introducing our new sponsors at Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/ Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/ You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Aceite de oliva, dieta mediterránea y evidencia científica — con Jesús de la OsadaEn este episodio converso con Jesús de la Osada García, doctor en Farmacia, catedrático de Bioquímica y Biología Molecular en la Universidad de Zaragoza y uno de los mayores expertos en aceite de oliva virgen extra y dieta mediterránea. Juntos analizamos qué hay realmente detrás de los titulares que hablan del “oro líquido”:
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Stuart Watson and Mark Heath convene to pick the bones out of a dreadfully deflating evening at Portman Road last night, which saw Town humbled 3-0 by Charlton. The boys reflect briefly on the game before pondering some wider themes - does McKenna know his best XI, why do they keep conceding poor goals and where are the leaders? There's also a chat about tactics, Stu's strong verdict on the game and whether it really is time to panic. Then we finish with a look ahead to Fabio Wardley's big fight against Joseph Parker at the O2 Arena this weekend. Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/ Introducing our new sponsors at Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/ Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/ You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Mark Heath catches up with Suffolk heavyweight star Fabio Wardley ahead of his huge fight with ex-world champ Joseph Parker at the 02 this weekend. The pair reflect on Fab's Portman Road fight and him becoming a dad just days later, before looking ahead to the Parker test. Fab explains why he took the fight, what he expects from Parker as an opponent and how he wins the clash. There's also a chat about Fab's remarkable journey to this point - and his thoughts on the man he could face next if he beats Parker, the extraordinary Oleksandr Usyk. Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/ Introducing our new sponsors at Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/ Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/ You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Send us a textToday, I'm joined by Dr. William LaValley — one of the world's leading researchers and medical doctors in the field of integrative cancer treatment.Dr. LaValley has spent decades combining the latest discoveries in molecular biology with evidence-based, integrative therapies for cancer. He draws upon the vast database of research available through PubMed to identify the anti-cancer potential of natural compounds and repurposed, or off-label, pharmaceutical drugs.Since earning his M.D. in 1986, Dr. LaValley has developed sophisticated, evidence-driven databases mapping the molecular pathways of cancer. These insights have allowed him to design personalized treatment protocols that complement — rather than replace — conventional chemotherapy and radiation therapy.In this episode, we'll discuss how understanding molecular biology helps identify new targets for treatment, how repurposed drugs can work synergistically with standard therapies, and what the future of integrative oncology looks like.You can find him at:www.Lavalleymdprotocols.com#IntegrativeOncology #CancerResearch #MolecularMedicine #RepurposedDrugs #FunctionalMedicine #CancerTreatment #FitRxPodcast
Joan Slonczewski is a microbiologist at Kenyon College and a science fiction writer who explores biology and space travel. Their books have twice earned the John W. Campbell Memorial Award for Best Science Fiction Novel: "A Door into Ocean" and "The Highest Frontier". Their latest novel is "Minds in Transit". With John W. Foster and Erik Zinser, they coauthor the textbook, Microbiology: An Evolving Science.In Sentientist Conversations we talk about the most important questions: “what's real?”, “who matters?” and "how can we make a better world?"Sentientism answers those questions with "evidence, reason & compassion for all sentient beings." The video of our conversation is here on YouTube.00:00 Clips00:51 Welcome03:10 Joan's Intro- Catholic Italian/Polish immigrant background "I project that into my thinking about the world... we're all immigrants one way or another"- Molecular microbiology at Kenyon College- Quakerism "quite consistent actually with the experimental world"- #scifi writing and Minds in Transit "the protagonist is an artist whose mind is filled with sentient microbes" & machine minds "she has to negotiate with her house as an intelligent entity"- The Mike Levin Sentientism episode & multiple levels of organisation, intelligence, analysis- "What is intelligence... on multiple levels"- Studying individual microbes / bacteria "organs for sensing and response"- "How do we know what they [the microbes] might be thinking or feeling"- "The microbial communities of our gut act as part of our brain... contribute to how our own brains think and feel"- Writing Brain Plague "That's my science fiction universe... but it's almost become real... we think of microbial communities as part of our brain"- Challenging our concept of intelligence: "What does it mean that a part of our intelligence and response is determined by a community of microscopic bacteria?"- Catholic parents "they did not practice religion at all but I think they inherited a strong sense of righteousness and justice from the Catholic tradition"- "A strong materialist tradition"... Father an IBM physicist, nominated for the Nobel prize re: work on magnetism- Mother a violin teacher- "I grew up with a sense of science and music... largely as a material worldview"- "Before I could read and write I knew I that I was going to be a scientist like my father"- Writing a first "scientific paper" in crayon- "There was never a question that I viewed the world in scientific terms... anything, to be true had to be recognised byexperiment"09:46 What's Real?27:00 What and Who Matters?01:14:57 A Better World?01:31:45: Follow Joan:- Minds in Transit at Bookshop.org- Joan's Home Page- Joan at Kenyon College- Joan on Wikipedia- Quakers in the UKAnd more... full show notes at Sentientism.info.Sentientism is “Evidence, reason & compassion for all sentient beings.” More at Sentientism.info. Join our "I'm a Sentientist" wall via this simple form.Everyone, Sentientist or not, is welcome in our groups. The biggest so far is here on FaceBook. Come join us there!
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Ross Halls is joined by Stuart Watson and Alex Jones to reflect on Ipswich Town's 2-1 defeat at Middlesbrough. Recording from the lobby of their Premier Inn down the road from the Riverside Stadium, the boys look back on what went wrong for Town up on Teesside. There's chat about George Hirst's penalty miss, Cedric Kipré's own goal and a dramatic second half, where the Blues didn't have enough to take a result back to Suffolk. Then it's onto Charlton. What threats will they pose, and will Kieran McKenna look to make any changes? There's also some late-night shenanigans in a rough-and-ready podcast recorded just hours after the full-time whistle. Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/ Introducing our new sponsors at Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/ Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/ You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Alex Jones, Ross Halls and Mark Heath are back to discuss all things Ipswich Town after the latest pointless international break. The boys try to predict the next six games which lie ahead of the Blues, and then pick out their star students from the season so far. We put some other players in detention too, before focusing on Friday night's trip to high-flying Middlesbrough. Then we finish with a chat about the Traitors, and Mark gets misty-eyed about Drizzy. Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/ Introducing our new sponsors at Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/ Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/ You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Ross Halls is joined by Simon Barlett and Liam Young to discuss all things Ipswich Town. The boys start with the reports on Kieran McKenna talks with Rangers, Jack Taylor signing a new deal and Wes Burns role when he returns from injury. They also discuss their player of the season so far and thoughts on the trip to Middlesbrough. Plus the latest edition of The Strike!] Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/ Introducing our new sponsors at Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/ Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/ You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Molecular epidemiologist Krystle Kuhs, Ph.D., professor in the Department of Epidemiology and Environmental Health in the College of Public Health, leads three large clinical studies evaluating biomarker-based screening for early detection of HPV-driven throat cancer, a rapidly increasing cancer that disproportionately affects Kentuckians, especially in Appalachia, and for which no screening methods exist. She talks about the effort on this week's edition of Dr. Greg Davis on Medicine.
In this episode of the Regaining Health and Humanitypodcast, Dr. Scott Johnson interviews Greg, known as the Hydrogen Man, who shares his transformative journey into hydrogen therapy after facing severe health challenges. Greg discusses the revolutionary potential of molecular hydrogen in improving health, the limitations of traditional Western medicine, and the importance of clean water. He provides real-life testimonials of individuals who have experienced significant health improvements through hydrogentherapy and addresses common misconceptions surrounding its use. The conversation emphasizes the need for proper methods of hydrogen application, practical tips for integrating it into daily life, and the critical role ofnutrition and lifestyle in overall health. Greg concludes by highlighting hydrogen's protective effects against various diseases, encouraging listeners to explore this natural solution further.Connect with Dr. Scott A. Johnsonauthorscott.comFacebook Instagram YouTube Links to purchase books Connect with Greghttps://holyhydrogen.com/https://www.facebook.com/holyhydrogen/https://www.instagram.com/holy.hydrogen?igsh=ZmMxZHV4dGtwbm53https://x.com/holy.hydrogen1 TakeawaysHydrogen therapy is a powerful natural solution for health.Greg's near-death experience led him to explore hydrogen therapy.Western medicine often has limitations in treating chronic conditions.Molecular hydrogen can revolutionize health and wellness.Real-life testimonials showcase the effectiveness of hydrogen therapy.Clean water is essential for health and hydrogen therapy.Common misconceptions about hydrogen therapy need to be addressed.Different methods of using hydrogen offer various benefits.Integrating hydrogen therapy into daily life is practical and beneficial.Nutrition and lifestyle play a crucial role in health outcomes. Chapters00:00 Introduction to Hydrogen Therapy01:47 Understanding Molecular Hydrogen03:04 The Journey to Hydrogen Advocacy05:24 The Limitations of Western Medicine08:43 The Impact of Hydrogen on Health12:34 Common Misconceptions about Hydrogen Therapy18:50 The Pursuit of Quality Over Profit19:08 Understanding Hydrogen Therapy Methods21:34 The Importance of Reliable Hydrogen Devices22:42 Integrating Hydrogen Therapy into Daily Life25:15 The Role of Clean Water and Nutrition26:31 The Impact of Nutritional Deficiencies32:43 Hydrogen's Protective Properties35:15 Short Outro.m4v
Episode 240 brings a transmission from Decoder, the Dallas-based artist crafting hyper-minimalist body music with a distinct sci-fi sensibility. Through releases on storied labels like Axis and Molecular, as well as modern outposts such as Blank Code, Float, AMTK+, and his own imprints Codec and Toca Records, Decoder has shaped a sound that feels engineered [...] The post Blank Code Podcast 240 – Decoder first appeared on Blank Code.
This week I interviewed Dr. Bill Andrews. He holds a Ph.D. in Molecular & Population Genetics, has over 50 patents in anti-aging and genetics innovations, and his leadership led to the discovery of human telomerase, the enzyme connected to cellular aging. We discussed lifestyle factors to help slow down aging along with:- His research around telomeres - Dr. Andrew's favorite nutraceuticals to lengthen telomeres- Exercises to live longerand his one tip to get your body back to what it once was!Connect with Dr. Billhttps://sierrasci.com/dr-bill-andrews/Get Telo-Vital for a 55% discount! https://getleaneatclean.thegoodinside.com/special-offer-telo-vital-lp------------Links:Interested in Upgrading your Mitochondria, Improving Energy and Sleep! Check out Troscriptions: https://bit.ly/4ik5kK5Use Discount Code for 10% OFF: EATCLEAN----Watch Get Lean Eat Clean podcast video episodes on YouTube!YouTube.com/@briangryn3680-----How to Take Simple Steps to Reclaim the Body, Energy, and Strength You Had 10-15 Years Ago Using My Stepladder System:https://www.stepladdersystem.com/----B.rad Whey Protein Isolate Superfuel:The Best Protein on The Planet! Available in Two Delicious Flavors: Vanilla Bean and Cocoa BeanUse Coupon Code glec10off for 10% off your order!Amazon (case sensitive): GLEC10OFFB.rad Nutrition.com: glec10offhttps://a.co/d/731gssV----My favorite health bars with clean ingredients!https://www.eatprima.com/BRIAN6816310% OFF with this link!----| Listen to the Get Lean Eat Clean Podcast |►Apple Podcasts | https://podcasts.apple.com/us/podcast/get-lean-eat-clean/id1540391210►Spotify | https://open.spotify.com/show/0QmJzYZsdV6tUNbDxaPJjS| Connect with Brian |►Website | https://www.briangryn.com►Instagram | https://www.instagram.com/bdgryn►Facebook | https://www.facebook.com/getleanandeatclean►Twitter | https://twitter.com/grynnerwinner
Join Dr. Paloma Giangrande, Editor-in-Chief of Molecular Therapy Nucleic Acids, as she discusses a recently published MTNA article, Controlling CRISPR-Cas9 genome editing in human cells using a molecular glue degrader, with its authors Drs. Krishanu Saha and Namita Khajanchi (UW-Madison). If you enjoy this episode, check out our hybrid event this fall that will allow you to engage with pioneering researchers in gene editing! Breakthroughs in Targeted In Vivo Gene Editing will be held in San Diego and virtually November 20-21, 2025. Music: 'Electric Dreams' by Scott Buckley - released under CC-BY 4.0. www.scottbuckley.com.auShow your support for ASGCT!: https://asgct.org/membership/donateSee omnystudio.com/listener for privacy information.
AP correspondent Julie Walker reports 3 scientists win the Nobel prize in chemistry.
A @Christadelphians Video: Dr. S. Palmer discusses the relationship between science and the Bible, arguing they are not contradictory, but rather complementary.### Highlights-
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Stuart Watson, Alex Jones, Ross Halls and Mark Heath are back to bathe in the warm afterglow of Town finally beating Norwich in the East Anglian derby. The boys reflect on a historic day, relive the key moments, wax lyrical about Jaden's instant classic goal and hear from both Kieran McKenna and Big Cedric Kipre. There's praise for Ced, Jaden, the Town engine room and more, plus debates about the future for Jacob Greaves in the starting XI and whether Ivan Azon is pushing to unseat George Hirst as first choice. We revel in Town's brilliant bench too, savour Marcelino Nunez's star turn as the panto villain - and get a very special video message from Finland. Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/ Check out are other sponsor, Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/ Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/ You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Mark Heath, Stuart Watson, Ross Halls and Alex Jones bring you a special live KOA podcast building up to the East Anglian derby. We're joined by Paddy Davitt from the Pink Un to give us insight into the Norwich mood and narratives ahead of the game, plus get thoughts, questions and statements from the KOA Army. Then we review today's pressers, have a debate around the potential starting XI and try to pick out a few potential derby day heroes. We finish by looking at where the game will be won and lost - and offer our predictions! Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/ Introducing our new sponsors at Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/ Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/ You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Osteosarcoma Webinar Series: Alanna Church, MD, Associate Director, Laboratory for Molecular Pediatric Pathology at Boston Children's Hospital, Assistant Professor of Pathology at Harvard Medical School, and Conference Cochair joins us on OsteoBites to discuss insights and higlights from the AACR Special Conference in Cancer Research: Discovery and Innovation in Pediatric Cancer—From Biology to Breakthrough Therapies, September 25-28 in Boston.Dr. Church is currently a Molecular and Pediatric Pathologist at Boston Children's Hospital, where she is a founder and associate medical director of the Laboratory for Molecular Pediatric Pathology (LaMPP). She is an Assistant Professor of Pathology at Harvard Medical School, the Program Director for the Harvard Molecular Genetic Pathology Fellowship, and the incoming Chair of Clinical Practice for the Association for Molecular Pathology. Her clinical and research work focuses on bringing molecular testing to the clinical care of children with cancer. Through institutional projects (the Profile study, GAIN consortium study), she has profiled thousands of children's tumors and has used these results to make real-time impacts on their diagnoses and treatments. She is involved in national initiatives to improve the quality and access to molecular testing for children with cancer, including the NCI-funded Count Me In Study (Dana Farber, Broad Institute), the National Comprehensive Cancer Network, the National Institutes of Health, and the Children's Oncology Group.
In this episode of the Epigenetics Podcast, we talked with Mo Motamedi from the Center for Cancer Research at Massachusetts General Hospital about his work on RNA-mediated epigenetic regulation. The Interview starts with Dr. Motamedi sharing his personal journey into the realm of biology, sparked by a familial inclination towards science and a challenge to excel in a field that initially felt daunting. His passion was ignited during a genetics class, as he recognized the quantitative nature of the discipline amidst the evolution of modern techniques like qPCR and high-throughput sequencing. Dr. Motamedi goes on to articulate the importance of understanding the interplay between genetics and broader biological systems, emphasizing that an insightful grasp of evolution is vital for decoding cellular mechanisms. He reflects on his time in a postdoctoral lab under Danish Moazet, investigating RNA interference (RNAi) and its unexpected nuclear roles, contributing significantly to the understanding of how RNAi is involved in gene silencing via chromatin interaction. As his narrative unfolds, Dr. Motamedi provides deep insights into his own lab's work, which focuses on the establishment and maintenance of epigenetic states and their implications in cancer epigenetics. He discusses groundbreaking discoveries related to RNAi and heterochromatin, detailing experiments that unveil how specific proteins contribute to transcriptional and post-transcriptional gene silencing. A pivotal theme emerges: the complex dynamics of genome evolution and chromatin organization can be reshaped under various biological contexts, including the quiescent state of cells under stress. Moreover, the discussion traverses recent publications from Dr. Motamedi's lab, revealing how they identify long non-coding RNAs that function as silencers at centromeres, an essential mechanism that aids in the establishment of heterochromatin independently of RNAi. His findings advocate for the idea that well-structured genome organization can lead to more efficient gene regulation, which can also be crucial in therapeutic contexts for various cancers. References Motamedi, M. R., Hong, E. J., Li, X., Gerber, S., Denison, C., Gygi, S., & Moazed, D. (2008). HP1 proteins form distinct complexes and mediate heterochromatic gene silencing by nonoverlapping mechanisms. Molecular cell, 32(6), 778–790. https://doi.org/10.1016/j.molcel.2008.10.026 Joh, R. I., Khanduja, J. S., Calvo, I. A., Mistry, M., Palmieri, C. M., Savol, A. J., Ho Sui, S. J., Sadreyev, R. I., Aryee, M. J., & Motamedi, M. (2016). Survival in Quiescence Requires the Euchromatic Deployment of Clr4/SUV39H by Argonaute-Associated Small RNAs. Molecular cell, 64(6), 1088–1101. https://doi.org/10.1016/j.molcel.2016.11.020 Joh, R. I., Lawrence, M. S., Aryee, M. J., & Motamedi, M. (2021). Gene clustering drives the transcriptional coherence of disparate biological processes in eukaryotes. Systems Biology. https://doi.org/10.1101/2021.04.17.440292 Related Episodes Evolutionary Forces Shaping Mammalian Gene Regulation (Emily Wong) Chromatin Evolution (Arnau Sebé-Pedrós) The Role of lncRNAs in Tumor Growth and Treatment (Sarah Diermeier) Contact Epigenetics Podcast on Mastodon Epigenetics Podcast on Bluesky Dr. Stefan Dillinger on LinkedIn Active Motif on LinkedIn Active Motif on Bluesky Email: podcast@activemotif.com
Molecular-medicine expert Dr. Nathan Bryan explains how nitric oxide (NO) protects the endothelium, drives vasodilation, and influences energy, immunity, hormones, and longevity. He links stubborn hypertension and poor exercise tolerance to the microbiome–NO axis and outlines common NO killers—antiseptic mouthwashes and fluoride overuse, chronic PPIs, ultra-processed diets, and inactivity. We cover practical restores (movement, nutrient-dense food, targeted micronutrients, careful PPI weaning, ditching antiseptic rinses) and preview clinical work on NO-releasing lozenges for ischemic heart disease, approaches to improve cerebral blood flow and insulin signaling in cognitive decline, and topical NO for chronic wounds. Bryan also touches on food quality (glyphosate, soil health), hormone synergy with NO, and NO-based skincare that supports perfusion and collagen. Bottom line: rebuild NO, and the body's own repair systems can finally do their job.(Educational only; not personal medical advice.)Guest BioNathan S. Bryan, PhD is a molecular medicine researcher and leading authority on nitric oxide (NO) biochemistry. Over two decades, he has mapped how the body generates and uses NO—and what happens when it doesn't—publishing widely, authoring multiple books, and translating discoveries into products and late-stage drug trials. His work spans cardiovascular health, metabolism, neurocognition, wound healing, and skin biology, with a focus on restoring NO as a foundation for repair. Dr. Bryan speaks globally on NO and leads development of NO-based therapeutics targeting ischemic heart disease, Alzheimer's disease, and non-healing ulcers. GET SOCIAL WITH US!
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Ross Halls is joined by Alex Bell and Tom Barnsley-Bloomfield to discuss all things Ipswich Town. The boys reflect on the draw at Bristol City, overall feelings to the season so far and a big question around the leaders in the team. They then move on to derby day as they share their memories and thoughts ahead of the game at Portman Road. Plus the latest edition of The Strike! Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/ Introducing our new sponsors at Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/ Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/ You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Ross Halls is joined by Stuart Watson and Alex Jones to discuss Ipswich Town's 1-1 draw against Bristol City. Fresh off their trip to Ashton Gate, the boys reflect on the game, where Kieran McKenna made six changes to the side that beat Portsmouth, handing full debuts to Marcelino Nunez and Ivan Azon. Then it's onto the game, with Jack Clarke's penalty cancelling out Rob Atkinson's open. What more could the Blues have done to create chances against the Robins? There's also a quick chat about the upcoming East Anglian derby, looking ahead to our live podcast on Friday night ahead of the clash against Norwich City. Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/ Introducing our new sponsors at Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/ Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/ You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Ross Halls and Tom Cann are back with our Ipswich Town Women's podcast after a historic first WSL 2 win. The duo discuss a tough three game week for Joe Sheehan's side, who had started it away at Charlton, earning a point at the Valley. Then it was cup action as they were beaten 5-1 by WSL side Leicester City, but switching focus back to the league against Portsmouth. Plenty of talking points from the 3-2 win was discussed as the Blues earned their first three points of the season. Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/ Introducing our new sponsors at Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/ Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/ You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Many women in Perimenopause and Menopause struggle with unwanted weight gain and feel like nothing they have learned over the years is working. Turns out there are NEW guidelines to follow for weight loss after age 40. With a degree in Molecular and Cell Biology as well as an MBA, Nagina Abdullah blends scientific research with realistic strategies to help women lose weight and create sustainable healthy habits. You may think you have heard it all, but Nagina will share new tips for you. Tune in today!Connect with Carol Perlman:Website: http://www.carolperlman.com/ http://healthy4lifebycarolperlman.comFacebook: https://www.facebook.com/carol.w.perlmanInstagram: @carolperlmanLinkedIn: https://www.linkedin.com/in/carol-perlman-8a735513/Email: carolperlman@carolperlman.comMorning Momentum Mini Course FREE Download!https://courses.itsabouttimemanagement.com/morning-momentumNagina's website: https://masalabody.com/
Kings of Anglia - Ipswich Town podcast from the EADT and Ipswich Star
Stuart Watson, Ross Halls and Mark Heath are back to discuss all things Ipswich Town in the wake of their 2-1 win over Portsmouth. The boys chat about Jaden Philogene, Town's midfield marvels and their £34m bench boost, plus hear from Kieran McKenna and the freshly-shaven George Hirst. There are some thoughts on Sindre Walle Egeli too, as well as defensive concerns and a chat around who Town's best player is. Then it's onto tomorrow's tricky trip to Bristol City, who we'd rest for the game and our predictions. Plus, Mark already has eyes on a big money January striker target, and Ross makes a huge pronunciation breakthrough. Kings of Anglia is sponsored by Stardust Spirits. Get 20% OFF with promo code KOA at https://www.stardustspirits.co.uk/ Introducing our new sponsors at Molecular! Get 10% OFF with promo code KOA10 at https://www.molecular-uk.com/ Subscribe on our website to watch the video version of the podcast - https://www.eadt.co.uk/subscribe/ You can shop the KOA range here - (kings-of-anglia.myspreadshop.co.uk)
Let's sleep scientifically this week, with more from a woman of such deep and broad accomplishment that the word "scientist" had to be coined to describe her. This time, colors, molecular heat conduction, what constitutes smells, and why gold is really blue. Help us stay ad-free and 100% listener-supported! Patreon: https://www.patreon.com/boringbookspod Buy Me a Coffee: https://www.buymeacoffee.com/d5kcMsW Read “On Molecular and Microscopic Science” at Project Gutenberg: https://www.gutenberg.org/ebooks/55886 Music: "Cosmic Tingles,” by Lee Rosevere, licensed under CC BY, https://leerosevere.bandcamp.com If you'd like to suggest a copyright-free reading for soft-spoken relaxation to help you overcome insomnia, anxiety and other sleep issues, connect on our website, https://www.boringbookspod.com.