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Dramatic advances in ancient DNA technologies have revolutionized our understanding of the human past. As part of the CARTA symposium on Ancient DNA, the panelists answer questions about the diverse applications of archaeogenomics in shaping not only a new vision of the human past, but also in creating a greater understanding of the present and our shared human future. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41202]
Dramatic advances in ancient DNA technologies have revolutionized our understanding of the human past. As part of the CARTA symposium on Ancient DNA, the panelists answer questions about the diverse applications of archaeogenomics in shaping not only a new vision of the human past, but also in creating a greater understanding of the present and our shared human future. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41202]
CARTA - Center for Academic Research and Training in Anthropogeny (Video)
Dramatic advances in ancient DNA technologies have revolutionized our understanding of the human past. As part of the CARTA symposium on Ancient DNA, the panelists answer questions about the diverse applications of archaeogenomics in shaping not only a new vision of the human past, but also in creating a greater understanding of the present and our shared human future. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41202]
Dramatic advances in ancient DNA technologies have revolutionized our understanding of the human past. As part of the CARTA symposium on Ancient DNA, the panelists answer questions about the diverse applications of archaeogenomics in shaping not only a new vision of the human past, but also in creating a greater understanding of the present and our shared human future. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41202]
Dramatic advances in ancient DNA technologies have revolutionized our understanding of the human past. As part of the CARTA symposium on Ancient DNA, the panelists answer questions about the diverse applications of archaeogenomics in shaping not only a new vision of the human past, but also in creating a greater understanding of the present and our shared human future. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41202]
In this episode of Off Script, Josh, James, and Tom discuss the importance of innovation in Leeds and the broader UK, emphasizing the need for representation and funding for technology outside of London, triggered by an article Tom wrote titled "National purpose on AI". Tom shares insights on the historical context of innovation in Leeds, the role of academic research, and the success stories of tech companies in regions like Stoke-on-Trent. They also propose Manchester as a suitable location for Lovelace Labs and call for a national data library to be established in Leeds. The discussion highlights the need for a more confident and proactive approach to promoting Northern innovation and addressing funding disparities. The UK government often overlooks innovation happening outside London. Leeds has a rich history of innovation and should be recognized for it. The tech sector in Stoke-on-Trent is surprisingly larger than in Oxford. Academic research is crucial for innovation but often underfunded outside major cities. There is a need for a national data library to be based in Leeds. Manchester is a strong candidate for the proposed Lovelace Labs. Local companies need to be more vocal about their contributions to the economy. Funding for innovation should be more evenly distributed across the UK. The North should celebrate its successes and promote its strengths more actively. A cultural shift is needed to demand more respect and representation for Northern innovation.
Genetic data is transforming the understanding of our own species and refining historical chapters at different scales around the globe. However, despite the globalization of biotechnologies to analyze the human genome, indigenous populations from the Americas and Oceania remain underrepresented in large-scale genomic studies. Andrés Moreno-Estrada, Cinvestav, discusses recent efforts to characterize the genetic profile of Indigenous Americans throughout the analysis of ancient and modern DNA, as well as their relationship within and beyond the continent, including the possibility of prehistoric contacts with Pacific Islanders. This topic poses challenges and opportunities to adequately study human diversity not only for the benefit of genetic research and science, but also for the benefit of the local communities, which are bearers of a unique evolutionary history that has been recorded in their DNA. This rapidly evolving field also raises questions about the best practices when studying the DNA of underrepresented ancestries while conducting cutting-edge science in a more equitable way. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41201]
Genetic data is transforming the understanding of our own species and refining historical chapters at different scales around the globe. However, despite the globalization of biotechnologies to analyze the human genome, indigenous populations from the Americas and Oceania remain underrepresented in large-scale genomic studies. Andrés Moreno-Estrada, Cinvestav, discusses recent efforts to characterize the genetic profile of Indigenous Americans throughout the analysis of ancient and modern DNA, as well as their relationship within and beyond the continent, including the possibility of prehistoric contacts with Pacific Islanders. This topic poses challenges and opportunities to adequately study human diversity not only for the benefit of genetic research and science, but also for the benefit of the local communities, which are bearers of a unique evolutionary history that has been recorded in their DNA. This rapidly evolving field also raises questions about the best practices when studying the DNA of underrepresented ancestries while conducting cutting-edge science in a more equitable way. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41201]
CARTA - Center for Academic Research and Training in Anthropogeny (Video)
Genetic data is transforming the understanding of our own species and refining historical chapters at different scales around the globe. However, despite the globalization of biotechnologies to analyze the human genome, indigenous populations from the Americas and Oceania remain underrepresented in large-scale genomic studies. Andrés Moreno-Estrada, Cinvestav, discusses recent efforts to characterize the genetic profile of Indigenous Americans throughout the analysis of ancient and modern DNA, as well as their relationship within and beyond the continent, including the possibility of prehistoric contacts with Pacific Islanders. This topic poses challenges and opportunities to adequately study human diversity not only for the benefit of genetic research and science, but also for the benefit of the local communities, which are bearers of a unique evolutionary history that has been recorded in their DNA. This rapidly evolving field also raises questions about the best practices when studying the DNA of underrepresented ancestries while conducting cutting-edge science in a more equitable way. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41201]
Genetic data is transforming the understanding of our own species and refining historical chapters at different scales around the globe. However, despite the globalization of biotechnologies to analyze the human genome, indigenous populations from the Americas and Oceania remain underrepresented in large-scale genomic studies. Andrés Moreno-Estrada, Cinvestav, discusses recent efforts to characterize the genetic profile of Indigenous Americans throughout the analysis of ancient and modern DNA, as well as their relationship within and beyond the continent, including the possibility of prehistoric contacts with Pacific Islanders. This topic poses challenges and opportunities to adequately study human diversity not only for the benefit of genetic research and science, but also for the benefit of the local communities, which are bearers of a unique evolutionary history that has been recorded in their DNA. This rapidly evolving field also raises questions about the best practices when studying the DNA of underrepresented ancestries while conducting cutting-edge science in a more equitable way. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41201]
Genetic data is transforming the understanding of our own species and refining historical chapters at different scales around the globe. However, despite the globalization of biotechnologies to analyze the human genome, indigenous populations from the Americas and Oceania remain underrepresented in large-scale genomic studies. Andrés Moreno-Estrada, Cinvestav, discusses recent efforts to characterize the genetic profile of Indigenous Americans throughout the analysis of ancient and modern DNA, as well as their relationship within and beyond the continent, including the possibility of prehistoric contacts with Pacific Islanders. This topic poses challenges and opportunities to adequately study human diversity not only for the benefit of genetic research and science, but also for the benefit of the local communities, which are bearers of a unique evolutionary history that has been recorded in their DNA. This rapidly evolving field also raises questions about the best practices when studying the DNA of underrepresented ancestries while conducting cutting-edge science in a more equitable way. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41201]
The human genetic history of South Asia has been shaped by its pivotal location at the crossroads of East and West Eurasia, dramatic landscapes such as the Himalayas, and longstanding socio-cultural practices like endogamy. A consequence is the diversity of East and West Eurasian genetic ancestral lineages found in South Asians today. Maanasa Raghavan, professor at the University of Chicago, explains that the increasing genome-wide data from ancient and present-day humans are providing emerging insights into the demographic processes that underlie present-day genetic diversity of South Asians and how they interface with evidence from archaeology, anthropology, linguistics, and oral histories. Human history in South Asia is also closely intertwined with the animals that humans domesticated, traded, and moved with them, offering yet another window into the dynamics of human mobility and connectivity in the past. Raghavanon's talk focuses on ancient and modern DNA insights into the origins of present-day human genetic diversity in South Asia, evolutionary history of domesticates, and broader implications for our understanding of human movements and interactions across Eurasia. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41200]
The human genetic history of South Asia has been shaped by its pivotal location at the crossroads of East and West Eurasia, dramatic landscapes such as the Himalayas, and longstanding socio-cultural practices like endogamy. A consequence is the diversity of East and West Eurasian genetic ancestral lineages found in South Asians today. Maanasa Raghavan, professor at the University of Chicago, explains that the increasing genome-wide data from ancient and present-day humans are providing emerging insights into the demographic processes that underlie present-day genetic diversity of South Asians and how they interface with evidence from archaeology, anthropology, linguistics, and oral histories. Human history in South Asia is also closely intertwined with the animals that humans domesticated, traded, and moved with them, offering yet another window into the dynamics of human mobility and connectivity in the past. Raghavanon's talk focuses on ancient and modern DNA insights into the origins of present-day human genetic diversity in South Asia, evolutionary history of domesticates, and broader implications for our understanding of human movements and interactions across Eurasia. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41200]
CARTA - Center for Academic Research and Training in Anthropogeny (Video)
The human genetic history of South Asia has been shaped by its pivotal location at the crossroads of East and West Eurasia, dramatic landscapes such as the Himalayas, and longstanding socio-cultural practices like endogamy. A consequence is the diversity of East and West Eurasian genetic ancestral lineages found in South Asians today. Maanasa Raghavan, professor at the University of Chicago, explains that the increasing genome-wide data from ancient and present-day humans are providing emerging insights into the demographic processes that underlie present-day genetic diversity of South Asians and how they interface with evidence from archaeology, anthropology, linguistics, and oral histories. Human history in South Asia is also closely intertwined with the animals that humans domesticated, traded, and moved with them, offering yet another window into the dynamics of human mobility and connectivity in the past. Raghavanon's talk focuses on ancient and modern DNA insights into the origins of present-day human genetic diversity in South Asia, evolutionary history of domesticates, and broader implications for our understanding of human movements and interactions across Eurasia. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41200]
The human genetic history of South Asia has been shaped by its pivotal location at the crossroads of East and West Eurasia, dramatic landscapes such as the Himalayas, and longstanding socio-cultural practices like endogamy. A consequence is the diversity of East and West Eurasian genetic ancestral lineages found in South Asians today. Maanasa Raghavan, professor at the University of Chicago, explains that the increasing genome-wide data from ancient and present-day humans are providing emerging insights into the demographic processes that underlie present-day genetic diversity of South Asians and how they interface with evidence from archaeology, anthropology, linguistics, and oral histories. Human history in South Asia is also closely intertwined with the animals that humans domesticated, traded, and moved with them, offering yet another window into the dynamics of human mobility and connectivity in the past. Raghavanon's talk focuses on ancient and modern DNA insights into the origins of present-day human genetic diversity in South Asia, evolutionary history of domesticates, and broader implications for our understanding of human movements and interactions across Eurasia. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41200]
The human genetic history of South Asia has been shaped by its pivotal location at the crossroads of East and West Eurasia, dramatic landscapes such as the Himalayas, and longstanding socio-cultural practices like endogamy. A consequence is the diversity of East and West Eurasian genetic ancestral lineages found in South Asians today. Maanasa Raghavan, professor at the University of Chicago, explains that the increasing genome-wide data from ancient and present-day humans are providing emerging insights into the demographic processes that underlie present-day genetic diversity of South Asians and how they interface with evidence from archaeology, anthropology, linguistics, and oral histories. Human history in South Asia is also closely intertwined with the animals that humans domesticated, traded, and moved with them, offering yet another window into the dynamics of human mobility and connectivity in the past. Raghavanon's talk focuses on ancient and modern DNA insights into the origins of present-day human genetic diversity in South Asia, evolutionary history of domesticates, and broader implications for our understanding of human movements and interactions across Eurasia. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41200]
Ancient DNA has revolutionized the study of the human past, providing unprecedented insights into ancient migrations and interactions among populations. Central Asia, due to its geographic location between Europe and Asia, has seen experienced diverse human and hominin migrations, which have been a focus of genetic, archaeological, linguistic, and historical research. Ainash Childebayeva, professor at the University of Texas at Austin, discusses recent advances in population genetics which have revealed the complex ancestry of Central Asian groups, both modern and ancient. Significant progress has also been made in understanding the role of natural selection in shaping genetic variation across the region. Childebayeva presents recent developments in our knowledge of Central Asia's genetic history, integrating findings from both modern and ancient genomic studies. Additionally, she highlights the selective pressures that have influenced the genomes of Central Asians through time, shedding light on the dynamic interplay between admixture, adaptation, and cultural change. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41199]
Ancient DNA has revolutionized the study of the human past, providing unprecedented insights into ancient migrations and interactions among populations. Central Asia, due to its geographic location between Europe and Asia, has seen experienced diverse human and hominin migrations, which have been a focus of genetic, archaeological, linguistic, and historical research. Ainash Childebayeva, professor at the University of Texas at Austin, discusses recent advances in population genetics which have revealed the complex ancestry of Central Asian groups, both modern and ancient. Significant progress has also been made in understanding the role of natural selection in shaping genetic variation across the region. Childebayeva presents recent developments in our knowledge of Central Asia's genetic history, integrating findings from both modern and ancient genomic studies. Additionally, she highlights the selective pressures that have influenced the genomes of Central Asians through time, shedding light on the dynamic interplay between admixture, adaptation, and cultural change. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41199]
CARTA - Center for Academic Research and Training in Anthropogeny (Video)
Ancient DNA has revolutionized the study of the human past, providing unprecedented insights into ancient migrations and interactions among populations. Central Asia, due to its geographic location between Europe and Asia, has seen experienced diverse human and hominin migrations, which have been a focus of genetic, archaeological, linguistic, and historical research. Ainash Childebayeva, professor at the University of Texas at Austin, discusses recent advances in population genetics which have revealed the complex ancestry of Central Asian groups, both modern and ancient. Significant progress has also been made in understanding the role of natural selection in shaping genetic variation across the region. Childebayeva presents recent developments in our knowledge of Central Asia's genetic history, integrating findings from both modern and ancient genomic studies. Additionally, she highlights the selective pressures that have influenced the genomes of Central Asians through time, shedding light on the dynamic interplay between admixture, adaptation, and cultural change. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41199]
Ancient DNA has revolutionized the study of the human past, providing unprecedented insights into ancient migrations and interactions among populations. Central Asia, due to its geographic location between Europe and Asia, has seen experienced diverse human and hominin migrations, which have been a focus of genetic, archaeological, linguistic, and historical research. Ainash Childebayeva, professor at the University of Texas at Austin, discusses recent advances in population genetics which have revealed the complex ancestry of Central Asian groups, both modern and ancient. Significant progress has also been made in understanding the role of natural selection in shaping genetic variation across the region. Childebayeva presents recent developments in our knowledge of Central Asia's genetic history, integrating findings from both modern and ancient genomic studies. Additionally, she highlights the selective pressures that have influenced the genomes of Central Asians through time, shedding light on the dynamic interplay between admixture, adaptation, and cultural change. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41199]
Ancient DNA has revolutionized the study of the human past, providing unprecedented insights into ancient migrations and interactions among populations. Central Asia, due to its geographic location between Europe and Asia, has seen experienced diverse human and hominin migrations, which have been a focus of genetic, archaeological, linguistic, and historical research. Ainash Childebayeva, professor at the University of Texas at Austin, discusses recent advances in population genetics which have revealed the complex ancestry of Central Asian groups, both modern and ancient. Significant progress has also been made in understanding the role of natural selection in shaping genetic variation across the region. Childebayeva presents recent developments in our knowledge of Central Asia's genetic history, integrating findings from both modern and ancient genomic studies. Additionally, she highlights the selective pressures that have influenced the genomes of Central Asians through time, shedding light on the dynamic interplay between admixture, adaptation, and cultural change. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41199]
Over the past decade, archaeogenetics has analyzed more than 15,000 ancient genomes spanning 45,000 years of western Eurasian prehistory, uncovering dozens of migrations that reshaped Europe. Johannes Krause, Max Planck Institute, traces the earliest, unsuccessful attempts of modern humans to settle Europe after leaving Africa around 50,000 years ago, when they also interbred with Neandertals. Krause examines two major genetic turnovers of the Neolithic: the spread of early farmers from Anatolia about 8,000 years ago, who brought agriculture and domesticated animals and later mixed with indigenous hunter-gatherers; and the arrival of mobile herders from the Pontic steppe around 5,000 years ago, who introduced pastoralism and possibly Indo-European languages. Finally, he considers migrations triggered by the collapse of the Roman Empire, showing how large-scale mobility created the multiple ancestral strands found in modern Europeans. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41198]
Over the past decade, archaeogenetics has analyzed more than 15,000 ancient genomes spanning 45,000 years of western Eurasian prehistory, uncovering dozens of migrations that reshaped Europe. Johannes Krause, Max Planck Institute, traces the earliest, unsuccessful attempts of modern humans to settle Europe after leaving Africa around 50,000 years ago, when they also interbred with Neandertals. Krause examines two major genetic turnovers of the Neolithic: the spread of early farmers from Anatolia about 8,000 years ago, who brought agriculture and domesticated animals and later mixed with indigenous hunter-gatherers; and the arrival of mobile herders from the Pontic steppe around 5,000 years ago, who introduced pastoralism and possibly Indo-European languages. Finally, he considers migrations triggered by the collapse of the Roman Empire, showing how large-scale mobility created the multiple ancestral strands found in modern Europeans. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41198]
CARTA - Center for Academic Research and Training in Anthropogeny (Video)
Over the past decade, archaeogenetics has analyzed more than 15,000 ancient genomes spanning 45,000 years of western Eurasian prehistory, uncovering dozens of migrations that reshaped Europe. Johannes Krause, Max Planck Institute, traces the earliest, unsuccessful attempts of modern humans to settle Europe after leaving Africa around 50,000 years ago, when they also interbred with Neandertals. Krause examines two major genetic turnovers of the Neolithic: the spread of early farmers from Anatolia about 8,000 years ago, who brought agriculture and domesticated animals and later mixed with indigenous hunter-gatherers; and the arrival of mobile herders from the Pontic steppe around 5,000 years ago, who introduced pastoralism and possibly Indo-European languages. Finally, he considers migrations triggered by the collapse of the Roman Empire, showing how large-scale mobility created the multiple ancestral strands found in modern Europeans. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41198]
Over the past decade, archaeogenetics has analyzed more than 15,000 ancient genomes spanning 45,000 years of western Eurasian prehistory, uncovering dozens of migrations that reshaped Europe. Johannes Krause, Max Planck Institute, traces the earliest, unsuccessful attempts of modern humans to settle Europe after leaving Africa around 50,000 years ago, when they also interbred with Neandertals. Krause examines two major genetic turnovers of the Neolithic: the spread of early farmers from Anatolia about 8,000 years ago, who brought agriculture and domesticated animals and later mixed with indigenous hunter-gatherers; and the arrival of mobile herders from the Pontic steppe around 5,000 years ago, who introduced pastoralism and possibly Indo-European languages. Finally, he considers migrations triggered by the collapse of the Roman Empire, showing how large-scale mobility created the multiple ancestral strands found in modern Europeans. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41198]
Over the past decade, archaeogenetics has analyzed more than 15,000 ancient genomes spanning 45,000 years of western Eurasian prehistory, uncovering dozens of migrations that reshaped Europe. Johannes Krause, Max Planck Institute, traces the earliest, unsuccessful attempts of modern humans to settle Europe after leaving Africa around 50,000 years ago, when they also interbred with Neandertals. Krause examines two major genetic turnovers of the Neolithic: the spread of early farmers from Anatolia about 8,000 years ago, who brought agriculture and domesticated animals and later mixed with indigenous hunter-gatherers; and the arrival of mobile herders from the Pontic steppe around 5,000 years ago, who introduced pastoralism and possibly Indo-European languages. Finally, he considers migrations triggered by the collapse of the Roman Empire, showing how large-scale mobility created the multiple ancestral strands found in modern Europeans. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41198]
Dramatic advances in ancient DNA technologies have revolutionized our understanding of the human past. Since the publication of the first ancient human genomes in 2010, the field of archaeogenomics has grown at an astonishing pace, and today the genomes of more than 10,000 ancient humans have been sequenced. Kicking off this symposium are CARTA Co-Director and Salk Institute President Jerry Joyce and event co-chair Johannes Krause. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41194]
Dramatic advances in ancient DNA technologies have revolutionized our understanding of the human past. Since the publication of the first ancient human genomes in 2010, the field of archaeogenomics has grown at an astonishing pace, and today the genomes of more than 10,000 ancient humans have been sequenced. Kicking off this symposium are CARTA Co-Director and Salk Institute President Jerry Joyce and event co-chair Johannes Krause. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41194]
CARTA - Center for Academic Research and Training in Anthropogeny (Video)
Dramatic advances in ancient DNA technologies have revolutionized our understanding of the human past. Since the publication of the first ancient human genomes in 2010, the field of archaeogenomics has grown at an astonishing pace, and today the genomes of more than 10,000 ancient humans have been sequenced. Kicking off this symposium are CARTA Co-Director and Salk Institute President Jerry Joyce and event co-chair Johannes Krause. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41194]
Dramatic advances in ancient DNA technologies have revolutionized our understanding of the human past. Since the publication of the first ancient human genomes in 2010, the field of archaeogenomics has grown at an astonishing pace, and today the genomes of more than 10,000 ancient humans have been sequenced. Kicking off this symposium are CARTA Co-Director and Salk Institute President Jerry Joyce and event co-chair Johannes Krause. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41194]
In this episode of The Brand Called You, MIT researcher Nils Fonstad unpacks digital innovation as a disciplined, impact-focused process. From end-user centricity to improvisation, modularity, and learning at scale, the conversation reveals how organizations can innovate without wasting resources—and turn digital from hype into measurable value.00:35- About Nils FonstadNils was educated at Cornell and MIT Sloan and earned his PhD from MIT.He has held senior research roles at INSEAD/eLab in Paris and MIT, publishing widely, including in Harvard Business Review.He co-founded the European CIO of the Year Awards with CIO Net and is currently based in Madrid.
The Kazakh and Mongolian Steppes span 5,000 kilometers west to east along the northern latitude of Asia. This unique ecozone allowed rapid movements of people, animals, goods, and ideas across Eurasia since prehistory and harbored numerous polities of pastoralists that made tremendous impacts on human history. However, the region's dynamic genetic history has been emerging only recently from archaeogenomic studies. Choongwon Jeong of Seoul National University discusses the current understanding of the region's genetic history, including the divergent genetic history of the Kazakh and Mongolian Steppe populations, the genetic interaction between the steppe pastoralists and their neighbors, and a comparison between the genetic history of human and domesticated animal populations. The emerging genetic view illuminates the poorly recorded history of the Kazakh and Mongolian Steppes and provides an interconnected perspective on the history of Eurasia. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41197]
The Kazakh and Mongolian Steppes span 5,000 kilometers west to east along the northern latitude of Asia. This unique ecozone allowed rapid movements of people, animals, goods, and ideas across Eurasia since prehistory and harbored numerous polities of pastoralists that made tremendous impacts on human history. However, the region's dynamic genetic history has been emerging only recently from archaeogenomic studies. Choongwon Jeong of Seoul National University discusses the current understanding of the region's genetic history, including the divergent genetic history of the Kazakh and Mongolian Steppe populations, the genetic interaction between the steppe pastoralists and their neighbors, and a comparison between the genetic history of human and domesticated animal populations. The emerging genetic view illuminates the poorly recorded history of the Kazakh and Mongolian Steppes and provides an interconnected perspective on the history of Eurasia. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41197]
CARTA - Center for Academic Research and Training in Anthropogeny (Video)
The Kazakh and Mongolian Steppes span 5,000 kilometers west to east along the northern latitude of Asia. This unique ecozone allowed rapid movements of people, animals, goods, and ideas across Eurasia since prehistory and harbored numerous polities of pastoralists that made tremendous impacts on human history. However, the region's dynamic genetic history has been emerging only recently from archaeogenomic studies. Choongwon Jeong of Seoul National University discusses the current understanding of the region's genetic history, including the divergent genetic history of the Kazakh and Mongolian Steppe populations, the genetic interaction between the steppe pastoralists and their neighbors, and a comparison between the genetic history of human and domesticated animal populations. The emerging genetic view illuminates the poorly recorded history of the Kazakh and Mongolian Steppes and provides an interconnected perspective on the history of Eurasia. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41197]
The Kazakh and Mongolian Steppes span 5,000 kilometers west to east along the northern latitude of Asia. This unique ecozone allowed rapid movements of people, animals, goods, and ideas across Eurasia since prehistory and harbored numerous polities of pastoralists that made tremendous impacts on human history. However, the region's dynamic genetic history has been emerging only recently from archaeogenomic studies. Choongwon Jeong of Seoul National University discusses the current understanding of the region's genetic history, including the divergent genetic history of the Kazakh and Mongolian Steppe populations, the genetic interaction between the steppe pastoralists and their neighbors, and a comparison between the genetic history of human and domesticated animal populations. The emerging genetic view illuminates the poorly recorded history of the Kazakh and Mongolian Steppes and provides an interconnected perspective on the history of Eurasia. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41197]
The Kazakh and Mongolian Steppes span 5,000 kilometers west to east along the northern latitude of Asia. This unique ecozone allowed rapid movements of people, animals, goods, and ideas across Eurasia since prehistory and harbored numerous polities of pastoralists that made tremendous impacts on human history. However, the region's dynamic genetic history has been emerging only recently from archaeogenomic studies. Choongwon Jeong of Seoul National University discusses the current understanding of the region's genetic history, including the divergent genetic history of the Kazakh and Mongolian Steppe populations, the genetic interaction between the steppe pastoralists and their neighbors, and a comparison between the genetic history of human and domesticated animal populations. The emerging genetic view illuminates the poorly recorded history of the Kazakh and Mongolian Steppes and provides an interconnected perspective on the history of Eurasia. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41197]
Humans have a deep and complex relationship with microbes. Beyond disease, microbes also profoundly shape human health and behavior through their activity in the microbiome and their diverse roles in food and cuisine. And yet we know very little about the origin, evolution, or ecology of the trillions of microorganisms that call us home. Christina Warinner of Harvard University discusses recent advances in genomic and proteomic technologies that are opening up dramatic new opportunities to investigate the complex and diverse microbial communities that have long inhabited our human bodies and our food systems - both in sickness and in health. From infectious disease to the microbiome, microbes are the invisible and often overlooked figures that have profoundly shaped human culture and influenced the course of human history. Warinner focuses on the long arc of human-microbial relationships preserved by ancient DNA over the past 100,000 years, and explores how emerging research on pathogen evolution and the recent loss of commensal microbes is changing how we understand human health – both today and in the past. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41196]
Humans have a deep and complex relationship with microbes. Beyond disease, microbes also profoundly shape human health and behavior through their activity in the microbiome and their diverse roles in food and cuisine. And yet we know very little about the origin, evolution, or ecology of the trillions of microorganisms that call us home. Christina Warinner of Harvard University discusses recent advances in genomic and proteomic technologies that are opening up dramatic new opportunities to investigate the complex and diverse microbial communities that have long inhabited our human bodies and our food systems - both in sickness and in health. From infectious disease to the microbiome, microbes are the invisible and often overlooked figures that have profoundly shaped human culture and influenced the course of human history. Warinner focuses on the long arc of human-microbial relationships preserved by ancient DNA over the past 100,000 years, and explores how emerging research on pathogen evolution and the recent loss of commensal microbes is changing how we understand human health – both today and in the past. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41196]
Humans have a deep and complex relationship with microbes. Beyond disease, microbes also profoundly shape human health and behavior through their activity in the microbiome and their diverse roles in food and cuisine. And yet we know very little about the origin, evolution, or ecology of the trillions of microorganisms that call us home. Christina Warinner of Harvard University discusses recent advances in genomic and proteomic technologies that are opening up dramatic new opportunities to investigate the complex and diverse microbial communities that have long inhabited our human bodies and our food systems - both in sickness and in health. From infectious disease to the microbiome, microbes are the invisible and often overlooked figures that have profoundly shaped human culture and influenced the course of human history. Warinner focuses on the long arc of human-microbial relationships preserved by ancient DNA over the past 100,000 years, and explores how emerging research on pathogen evolution and the recent loss of commensal microbes is changing how we understand human health – both today and in the past. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41196]
CARTA - Center for Academic Research and Training in Anthropogeny (Video)
Humans have a deep and complex relationship with microbes. Beyond disease, microbes also profoundly shape human health and behavior through their activity in the microbiome and their diverse roles in food and cuisine. And yet we know very little about the origin, evolution, or ecology of the trillions of microorganisms that call us home. Christina Warinner of Harvard University discusses recent advances in genomic and proteomic technologies that are opening up dramatic new opportunities to investigate the complex and diverse microbial communities that have long inhabited our human bodies and our food systems - both in sickness and in health. From infectious disease to the microbiome, microbes are the invisible and often overlooked figures that have profoundly shaped human culture and influenced the course of human history. Warinner focuses on the long arc of human-microbial relationships preserved by ancient DNA over the past 100,000 years, and explores how emerging research on pathogen evolution and the recent loss of commensal microbes is changing how we understand human health – both today and in the past. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41196]
Humans have a deep and complex relationship with microbes. Beyond disease, microbes also profoundly shape human health and behavior through their activity in the microbiome and their diverse roles in food and cuisine. And yet we know very little about the origin, evolution, or ecology of the trillions of microorganisms that call us home. Christina Warinner of Harvard University discusses recent advances in genomic and proteomic technologies that are opening up dramatic new opportunities to investigate the complex and diverse microbial communities that have long inhabited our human bodies and our food systems - both in sickness and in health. From infectious disease to the microbiome, microbes are the invisible and often overlooked figures that have profoundly shaped human culture and influenced the course of human history. Warinner focuses on the long arc of human-microbial relationships preserved by ancient DNA over the past 100,000 years, and explores how emerging research on pathogen evolution and the recent loss of commensal microbes is changing how we understand human health – both today and in the past. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41196]
Humans have a deep and complex relationship with microbes. Beyond disease, microbes also profoundly shape human health and behavior through their activity in the microbiome and their diverse roles in food and cuisine. And yet we know very little about the origin, evolution, or ecology of the trillions of microorganisms that call us home. Christina Warinner of Harvard University discusses recent advances in genomic and proteomic technologies that are opening up dramatic new opportunities to investigate the complex and diverse microbial communities that have long inhabited our human bodies and our food systems - both in sickness and in health. From infectious disease to the microbiome, microbes are the invisible and often overlooked figures that have profoundly shaped human culture and influenced the course of human history. Warinner focuses on the long arc of human-microbial relationships preserved by ancient DNA over the past 100,000 years, and explores how emerging research on pathogen evolution and the recent loss of commensal microbes is changing how we understand human health – both today and in the past. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41196]
Can we use LLMs to find who wrote the Bible? We're gonna try, and by we I mean: biologist Dr. Rutger Vos, Gil, and you, if you're interested. And if you are, send me a message at the bottom of this page.To read about the latest AI research into the Bible, click here Join our tribe on Patreon! Check out these cool pages on the podcast's website:Home PageWho wrote the Bible: Timeline and authorsAncient maps: easy to follow maps to see which empire ruled what and whenClick here to see Exodus divided into "sources" according to the Documentary Hypothesis The podcast is written, edited and produced by Gil Kidron
David Gokhman of the Weizmann Institute of Science explores how changes in gene regulation shaped recent human evolution. His team used massively parallel reporter assays in skeletal and neural cells to test 71,443 genetic variants that distinguish Neanderthals and Denisovans from modern humans, building a catalog that reveals hundreds of noncoding variants that alter gene expression. The work uncovers evolutionary trends and examples of convergent evolution, including an enhancer of KDM8, a gene involved in tumor progression, that was completely silenced in both archaic and modern human lineages through different mechanisms: motif disruption in Neanderthals and Denisovans, and hypermethylation in modern humans. Gokhman also introduces a way to reconstruct anatomical profiles from DNA sequence and methylation, using it to model Denisovan anatomy and scan the fossil record. The results suggest that the Harbin and Dali fossils were likely Denisovans, while Kabwe may have been related to the ancestor of Neanderthals and Denisovans, helping to clarify the regulatory changes underlying human evolution. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41195]
David Gokhman of the Weizmann Institute of Science explores how changes in gene regulation shaped recent human evolution. His team used massively parallel reporter assays in skeletal and neural cells to test 71,443 genetic variants that distinguish Neanderthals and Denisovans from modern humans, building a catalog that reveals hundreds of noncoding variants that alter gene expression. The work uncovers evolutionary trends and examples of convergent evolution, including an enhancer of KDM8, a gene involved in tumor progression, that was completely silenced in both archaic and modern human lineages through different mechanisms: motif disruption in Neanderthals and Denisovans, and hypermethylation in modern humans. Gokhman also introduces a way to reconstruct anatomical profiles from DNA sequence and methylation, using it to model Denisovan anatomy and scan the fossil record. The results suggest that the Harbin and Dali fossils were likely Denisovans, while Kabwe may have been related to the ancestor of Neanderthals and Denisovans, helping to clarify the regulatory changes underlying human evolution. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41195]
CARTA - Center for Academic Research and Training in Anthropogeny (Video)
David Gokhman of the Weizmann Institute of Science explores how changes in gene regulation shaped recent human evolution. His team used massively parallel reporter assays in skeletal and neural cells to test 71,443 genetic variants that distinguish Neanderthals and Denisovans from modern humans, building a catalog that reveals hundreds of noncoding variants that alter gene expression. The work uncovers evolutionary trends and examples of convergent evolution, including an enhancer of KDM8, a gene involved in tumor progression, that was completely silenced in both archaic and modern human lineages through different mechanisms: motif disruption in Neanderthals and Denisovans, and hypermethylation in modern humans. Gokhman also introduces a way to reconstruct anatomical profiles from DNA sequence and methylation, using it to model Denisovan anatomy and scan the fossil record. The results suggest that the Harbin and Dali fossils were likely Denisovans, while Kabwe may have been related to the ancestor of Neanderthals and Denisovans, helping to clarify the regulatory changes underlying human evolution. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41195]
The sequencing of genomes from archaic humans, such as Neanderthals and Denisovans, has transformed our understanding of human evolutionary history. These ancient genomes reveal that modern humans did not evolve in isolation but interbred with now-extinct groups, leaving lasting genetic legacies. To date, genomic sequences from 31 archaic human individuals, including four sequenced to high coverage, have provided unprecedented insights into the population structure, social organization, and adaptation of this now-extinct lineages, allowing us to reconstruct our own evolutionary history and the mechanisms that led to modern human success. Diyendo Massilani of Yale University School of Medicine reviews nearly three decades of research on archaic human DNA and what we have learned about how these groups lived, as well as how admixture between different lineages may have contributed both to the extinction of archaic humans and the thriving of modern humans. Ultimately, ancient genomes show that the success of our species was not predetermined but forged through encounters, exchanges, and adaptations, and that the legacies of archaic humans live on in our biology today, continuing to influence what it means to be human. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41193]
The sequencing of genomes from archaic humans, such as Neanderthals and Denisovans, has transformed our understanding of human evolutionary history. These ancient genomes reveal that modern humans did not evolve in isolation but interbred with now-extinct groups, leaving lasting genetic legacies. To date, genomic sequences from 31 archaic human individuals, including four sequenced to high coverage, have provided unprecedented insights into the population structure, social organization, and adaptation of this now-extinct lineages, allowing us to reconstruct our own evolutionary history and the mechanisms that led to modern human success. Diyendo Massilani of Yale University School of Medicine reviews nearly three decades of research on archaic human DNA and what we have learned about how these groups lived, as well as how admixture between different lineages may have contributed both to the extinction of archaic humans and the thriving of modern humans. Ultimately, ancient genomes show that the success of our species was not predetermined but forged through encounters, exchanges, and adaptations, and that the legacies of archaic humans live on in our biology today, continuing to influence what it means to be human. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41193]
CARTA - Center for Academic Research and Training in Anthropogeny (Video)
The sequencing of genomes from archaic humans, such as Neanderthals and Denisovans, has transformed our understanding of human evolutionary history. These ancient genomes reveal that modern humans did not evolve in isolation but interbred with now-extinct groups, leaving lasting genetic legacies. To date, genomic sequences from 31 archaic human individuals, including four sequenced to high coverage, have provided unprecedented insights into the population structure, social organization, and adaptation of this now-extinct lineages, allowing us to reconstruct our own evolutionary history and the mechanisms that led to modern human success. Diyendo Massilani of Yale University School of Medicine reviews nearly three decades of research on archaic human DNA and what we have learned about how these groups lived, as well as how admixture between different lineages may have contributed both to the extinction of archaic humans and the thriving of modern humans. Ultimately, ancient genomes show that the success of our species was not predetermined but forged through encounters, exchanges, and adaptations, and that the legacies of archaic humans live on in our biology today, continuing to influence what it means to be human. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41193]
The genome sequences of Neandertals and Denisovans have provided a wealth of new information about the origins, migrations, and interactions of ancient humans. These genomes have revealed that mixture between hominin groups was common: all modern humans outside Africa carry around 2% Neandertal DNA from a single major episode of Neandertal gene flow, while the ancestors of present-day Asians and Oceanians also met and mixed with multiple, genetically distinct Denisovan populations. Archaeological evidence suggests multiple dispersals of modern humans out of Africa, with early fossils identified in East and Southeast Asia over 50 thousand years ago. In contrast, genomic studies indicate that all present-day non-African populations descend primarily from a single dispersal after ~50 ka, though the migration routes of ancestral populations across Eurasia and Oceania remain unclear. Janet Kelso, professor at Max Planck Institute for Evolutionary Anthropology, shows how using the distribution of Neandertal and Denisovan ancestry in ancient and present-day modern humans can determine when, where and how often modern and archaic humans met and mixed. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41192]