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Latest episodes from Health and Medicine (Audio)

Generation Patient: Driving Meaningful Change for the Future of Young Adults with Chronic and Rare Medical Conditions

Play Episode Listen Later May 20, 2025 42:39


As part of the 2025 Developmental Disabilities Conference, Sneha Dave talks about future healthcare as young adults with chronic and rare medical conditions grow older. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 40606]

Serving Tribal Communities: Improving Service Access and Equity

Play Episode Listen Later May 20, 2025 41:40


As part of the 2025 Developmental Disabilities Conference, Season Goodpasture, Founder and Executive Director, Acorns to Oak Trees, talks about improving access and equity in tribal communities. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 40607]

Hip Fracture Outcomes

Play Episode Listen Later May 18, 2025 1:33


Dr. Terence Friedlander reviews the various patient outcomes after hip fracture surgery. Series: "Excerpts" [Health and Medicine] [Show ID: 40752]

What Does Muscle Do For Us?

Play Episode Listen Later May 16, 2025 4:08


The risk for many chronic diseases is directly linked to metabolic changes in the body and loss of muscle mass often associated with aging. In this excerpt, Dr. Natalie Marshall focuses on the role that muscles play in the body. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 40685]

The Master Plan for Developmental Services

Play Episode Listen Later May 14, 2025 41:23


As part of the 2025 Developmental Disabilities Conference, Amy Westling and Melissa Drake discuss the plan for developmental services from CalHHS and DDS. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 40605]

Why Osteoporosis is Bad

Play Episode Listen Later May 14, 2025 1:19


Dr. Terence Friedlander discusses common issues brought on by osteoporosis. Series: "Excerpts" [Health and Medicine] [Show ID: 40751]

A High-Fiber Diet Boosts Health

Play Episode Listen Later May 9, 2025 9:58


Dr. Sean Spencer talks about the vast microbial world that lives within our guts — known as the gut microbiome — and how it supports our health. Dr. Spencer emphasizes the importance of a high-fiber diet in creating a healthy gut microbiome which increases overall health. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 40761]

Being the Change We Need: Recovering from the Pandemic Moving Forward

Play Episode Listen Later May 7, 2025 40:47


As part of the 2025 Developmental Disabilities Conference, Aaron Carruthers, Executive Director of the California State Council on Developmental Disabilities, talks about the journey of moving forward after the COVID-19 pandemic. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 40604]

3rd Annual Global Astrobiotechnology Hub

Play Episode Listen Later May 5, 2025 86:58


The 3rd Annual Global Astrobiotechnology Hub focuses on advancing the intersection of space exploration, biotechnology, and innovation. The program brings together scientists, researchers, and space professionals to discuss how space technologies can accelerate scientific breakthroughs, particularly in fields like personalized medicine and bioengineering. Key themes include the challenges of conducting real-time research in space, the need for specialized astronaut-scientists, and the potential of space for groundbreaking experiments, such as organoid growth and in-space manufacturing. Experts underscore the importance of public access to scientific data and highlight the role of new media in engaging the public with space research. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40389]

Stem Cells and Science in Space - Medicine Informing Novel Discoveries (MIND)

Play Episode Listen Later May 2, 2025 72:39


Scientists, leaders, and patients discuss the intersection of cutting-edge science and real-world impact. They explore the importance of patient perspectives in shaping medical advancements and how collaboration fuels groundbreaking research. Key scientific achievements in areas like regenerative medicine, cancer therapies, and space biology are highlighted. The group emphasizes the need for scientists to engage more with the public—through social media and media appearances—to help people understand and value the life-changing discoveries in science. Featuring: Catriona Jamieson, M.D., Ph.D. UC San Diego Sandra Dillon Patient Advocate Alexander Khalessi, M.D., M.B.A. UC San Diego Jana Stoudemire Celestial Strategy, LLC Alysson Muotri, Ph.D. UC San Diego Rebecca Moores Philanthropist and Patient Advocate Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40519]

Health Disparities For People With Developmental Disabilities

Play Episode Listen Later Apr 30, 2025 42:50


As part of the 2025 Developmental Disabilities Conference, Amged Soliman from the National Council on Disability provides an update on health disparities. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 40603]

What Does Exercise Do To The Body?

Play Episode Listen Later Apr 25, 2025 8:16


The risk for many chronic diseases is directly linked to metabolic changes in the body and loss of muscle mass often associated with aging. In this program, Dr. Natalie Marshall focuses on the importance of movement and exercise to improve metabolic fitness and overall wellbeing. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 40681]

What Causes Bone Loss?

Play Episode Listen Later Apr 23, 2025 1:51


Dr. Terence Friedlander discusses the various causes of bone loss. Series: "Excerpts" [Health and Medicine] [Show ID: 40750]

How To Slow Aging

Play Episode Listen Later Apr 14, 2025 3:03


How can you make choices today that could help you live longer and feel better? Gordon Saxe, M.D., Ph.D., explores the ways to slow the aging process and live a healthier life. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40601]

Sarcopenia: What You Need To Know

Play Episode Listen Later Apr 11, 2025 8:45


The risk for many chronic diseases is directly linked to metabolic changes in the body and loss of muscle mass often associated with aging. In this program, Dr. Natalie Marshall focuses on sarcopenia, low muscle mass, and the importance of strength training and body composition to improve metabolic fitness. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 40684]

Oxidative Stress: What You Need To Know

Play Episode Listen Later Apr 4, 2025 5:50


The risk for many chronic diseases is directly linked to metabolic changes in the body. In this program, Dr. Natalie Marshall focuses on the role of antioxidants and how they work against oxidative stress in the body. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 40682]

4 Steps To Behavioral Change

Play Episode Listen Later Mar 21, 2025 16:38


Anthony Lim, M.D., J.D., explores how small, intentional steps can lead to lasting behavioral change. Lim breaks down a simple, four-step framework to help people achieve their goals, whether it's improving health, forming better habits, or making positive life changes. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40602]

Stem Cells Space and Liver Metabolism - Medicine Informing Novel Discoveries (MIND)

Play Episode Listen Later Mar 17, 2025 57:40


Explore the cutting-edge intersection of space travel, biology, and health. Experts dive into the effects of microgravity and space radiation on mitochondrial function, DNA repair, and liver regeneration, shedding light on the unique challenges astronauts face during long-term missions. The discussion also touches on metabolic health, highlighting the role of diet and new pharmaceutical treatments like GLP-1 agonists in addressing modern-day health concerns. With engaging insights on how space research can inform breakthroughs on Earth, this talk is a must-watch for anyone interested in the future of human health and space exploration. Series: "MIND - Medicine Informing Novel Discoveries" [Health and Medicine] [Science] [Show ID: 40388]

Genes Are Not Destiny: What You Eat Matters

Play Episode Listen Later Mar 14, 2025 8:35


How can you make choices today that could help you live longer and feel better? Gordon Saxe, M.D., Ph.D. explores lifestyle choices, including diet, that can prevent, or slow, chronic diseases and improve overall health. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40600]

Decoding the Dark Side of the Human Genome: How Ancient Viruses Shape Aging

Play Episode Listen Later Mar 7, 2025 46:32


Michael J. Corley, Ph.D., explores groundbreaking research on aging, the role of ancient viruses in our DNA, and the impact of the gut microbiome on longevity. Corley discusses how stress, diet, and exercise influence our genetic health, highlighting the complex interplay between environmental factors and our biological systems. The conversation also touches on individualized treatment strategies and the exciting potential of microbiome science in aging research. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40266]

Diversity Equity and Inclusion in Education - Autism Tree Annual Neurodiversity Conference 2024

Play Episode Listen Later Mar 5, 2025 57:32


This panel focuses on empowering neurodiverse individuals and their families through open discussions about communication and connection. Participants share personal experiences, emphasizing the importance of providing a voice to those who may struggle to express themselves. Key themes include support, understanding, and the journey toward fostering independence and confidence. The panelists encourage parents to prioritize their well-being while navigating the challenges of raising neurodiverse children, creating a community that values shared learning and growth. Through inspiration and insight, the panel explores practical strategies for enhancing communication and building meaningful relationships. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Education] [Show ID: 40212]

Parents of Neurodiversity - Autism Tree Annual Neurodiversity Conference 2024

Play Episode Listen Later Feb 26, 2025 57:25


Ths discussion captures the experiences of parents raising neurodivergent children, emphasizing the importance of finding joy, fostering inclusion, and supporting sibling relationships. Parents share personal stories of resilience, from guiding neurotypical siblings to embrace their roles with love to advocating for inclusive school environments. They highlight the unexpected ways their children teach them patience and strength, as well as the deep sense of community that emerges when families, educators, and peers come together. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 40214]

Stem Cells Scientific Publishing - Sanford Stem Cell Symposium 2024

Play Episode Listen Later Feb 18, 2025 58:38


Karen Christman, Sheila Chari, Stella Hurtley, and Robert Stephenson explore academic publishing in stem cell research, focusing on reproducibility, collaboration, and public communication. Editors from top journals discuss curating impactful research, sharing clinical trial data, and addressing challenges in scaling and standardizing therapies. They emphasize bridging silos, advancing precision regenerative medicine, and navigating open access publishing to responsibly propel the field forward. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39940]

No More Sidekicks: Putting Authentic Characters Front and Center in Fiction and Popular Culture - Autism Tree Annual Neurodiversity Conference 2024

Play Episode Listen Later Feb 5, 2025 59:47


This engaging panel discussion delves into the evolving representation of autistic characters in literature, comics, and pop culture, featuring authors and creators who bring authentic perspectives to their work. The conversation highlights the importance of intentionality in storytelling, challenges stereotypes, and explores the nuances of portraying neurodiverse experiences with depth and empathy. Panelists share personal journeys, writing inspirations, and the transformative power of seeing oneself reflected in stories, creating a thoughtful and inclusive dialogue that resonates with readers of all ages. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Arts and Music] [Show ID: 40330]

Bridging the Gap: Intercontinental Collaboration on Histone Deacetylation

Play Episode Listen Later Jan 31, 2025 11:48


The human body is made up of billions of cells. These cells are the basic building blocks of life, and they work together to form tissues, organs, and systems that enable our body to function and carry out various activities. Each cell has its own specific function and role in maintaining the overall health and functionality of the body, but how do these cells know what to do? Researchers at UC San Diego and Hebrew University of Jerusalem share an intercontinental effort working to determine just that. Alon Goren and Itamar Simon discuss some of the work they are doing to learn more about the human body beyond the cellular level. [Health and Medicine] [Science] [Show ID: 40516]

Body Health = Brain Health

Play Episode Listen Later Jan 30, 2025 9:00


What's the secret to supporting a sharp mind at any age? In this program, Dr. Nancy Isenberg discusses the latest science-based practices to promote brain health and resiliency as we age. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 40508]

The Future of Precision Medicine: Stem Cells Gene Therapy and AI - Medicine Informing Novel Discoveries (MIND)

Play Episode Listen Later Jan 24, 2025 57:36


Learn about advancements in precision medicine, particularly the role of AI, stem cell research, and gene therapy. Experts highlight AI's potential in personalized treatments, diagnostics, and patient care. Key topics include RNA targeting therapies, base editing for gene mutations, and using stem cells for disease modeling and regeneration. AI's contribution to enhancing healthcare efficiency and decision-making is also explored, emphasizing its role in personalized medicine through large data sets. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39981]

The American Diet is Critically Fiber Deficient

Play Episode Listen Later Jan 16, 2025 8:43


A healthy microbiome can prevent disease and obesity. Dr. Sean Spencer discusses how a diet rich in fiber supports our health in various ways. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 40458]

Genetics Narrative Identity and the Ethics of Choosing Disability

Play Episode Listen Later Jan 15, 2025 65:42


According to the World Health Organization (WHO) an estimated 1.3 billion people or 16% of the global population have a significant disability. A disability is a condition that can be mental or physical, and can affect a person's vision, movement, thinking, learning, communication, hearing, mental health or social relationships. However, not all disabilities are the same. Some disabilities are genetic, passed down from generation to generation, while others may have been caused by an incident out of the person's control. In this episode of Exploring Ethics, Professor Joseph Stramondo will discuss the narrative, identity and ethics of choosing disability. Series: "Exploring Ethics" [Health and Medicine] [Humanities] [Science] [Show ID: 40241]

Ancestral Pathways: Exploring the Indigenous Roots of Regeneration

Play Episode Listen Later Jan 13, 2025 137:46


Join us for a dynamic panel discussion where experts explore the contributions of Indigenous practices to modern agriculture. The conversation highlights traditional ecological knowledge, addresses gaps in food access, and proposes strategies to promote food sovereignty. Panelists examine how Indigenous wisdom and contemporary innovation create equitable, sustainable food systems, amplify Indigenous voices, and inspire collaboration for a resilient future. Series: "Future Thought Leaders" [Health and Medicine] [Agriculture] [Show ID: 40171]

Sensory Issues in Autism: Impacts on Health and the Promise of Neuroscientific Discovery with Carissa Cascio - Autism Tree Annual Neurodiversity Conference 2024

Play Episode Listen Later Jan 10, 2025 35:20


Carissa Cascio, Ph.D., explores how autistic individuals perceive and process sensory experiences, focusing on internal sensations of the body, known as interoception, and their impact on emotions, anxiety, and sleep. Cascio highlights the challenges of heightened sensory awareness, including how it can disrupt rest, and underscores the importance of understanding these experiences to improve therapy and overall well-being. Cascio shares personal anecdotes and challenges myths about autism, emphasizing the rich internal worlds of autistic individuals. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Show ID: 40215]

Aging Health and the Power of Lifestyle Choices with Gordon Saxe

Play Episode Listen Later Jan 8, 2025 32:59


Gordon Saxe, M.D., Ph.D., reveals the secrets to slowing down the aging process and living a healthier life. He uncovers how aging affects everything from our bones and muscles to our brain, leading to issues like memory loss, fatigue, and weakened immune responses. How can you make choices today that could help you live longer and feel better? Saxe dives into groundbreaking research on caloric restriction, a powerful tool for extending lifespan, and how a plant-based diet can prevent chronic diseases and improve overall health. He also shares practical tips on exercise, stress management, and social connection that can help you stay sharp, strong, and energized as you age. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40322]

Uncovering Mechanisms of Neurodegenerative Diseases by CRISPR-Based Screens with Martin Kampmann

Play Episode Listen Later Jan 3, 2025 58:22


Martin Kampmann, Ph.D., explores how CRISPR screening and induced pluripotent stem cell (iPSC) technology can uncover new insights into neurological diseases such as Alzheimer's. His lab uses CRISPR to identify genes that influence protein aggregation and cellular vulnerability, focusing on neurons, astrocytes, and microglia derived from human stem cells. Kampmann highlights the roles of mitochondria, autophagy, and other cellular pathways in disease progression, emphasizing the importance of understanding both protective and damaging processes. He also discusses the potential contributions of glial cells—especially microglia and astrocytes—to neurodegeneration, sparking ideas for therapeutic targets. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39461]

Transferring Knowledge into Transformation: Building Lasting Personal Change through Awareness Intention and Action with Anthony Lim

Play Episode Listen Later Dec 27, 2024 29:56


Anthony Lim, M.D., J.D., explores how small, intentional steps can lead to lasting behavioral change. Lim breaks down a simple, four-step framework—awareness, intention, action, and reflection—to help people achieve their goals, whether it's improving health, forming better habits, or making positive life changes. Through real-life examples and insights from neuroscience, he emphasizes the power of connecting with your deeper "why," taking action, and practicing self-compassion. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40323]

Women and Girls on the Autism Spectrum: Recent Findings and New Directions with Christine Wu Nordahl - Autism Tree Annual Neurodiversity Conference 2024

Play Episode Listen Later Dec 26, 2024 35:13


Christine Wu Nordahl, Ph.F., offers an insightful exploration into the unique needs and experiences of autistic teens, focusing on fostering inclusive spaces. Highlighting themes of gender diversity, underdiagnosis in girls, and the impact of societal perceptions, she emphasizes the importance of tailored support for neurodiverse individuals. Through powerful participant stories and an inspiring poem, Nordahl underscores the resilience and creativity within the autistic community. Her passionate advocacy for better diagnostic tools and inclusive interventions makes this talk a must-watch for anyone seeking to understand and empower autistic youth. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Show ID: 40213]

A Closer Look at…Stem Cells and the Human Brain

Play Episode Listen Later Dec 23, 2024 57:28


Frank Furnari, Ph.D., and Alexander Khalessi, M.D., M.B.A., discuss exciting advancements in brain cancer research, focusing on glioblastoma, an aggressive and challenging tumor. They highlight how specific genetic mutations drive tumor growth and how targeting these mutations could lead to new treatments. They also delve into cutting-edge therapies, including using light to activate drugs aimed at combating cancer. A central theme of the talk is the complexity and ever-changing nature of these tumors, which makes them difficult to treat. However, technological breakthroughs, like single-cell genetic sequencing and lab-grown tumor models, are providing scientists with valuable insights into tumor behavior, paving the way for more personalized and effective treatment options in the future. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39871]

A Tale of Two Barriers: Plasticity of Lung Epithelium and Mesothelium

Play Episode Listen Later Dec 18, 2024 58:40


Le Xu, Ph.D., examines the intricate processes underlying lung development and disease, with a focus on idiopathic pulmonary fibrosis (IPF). Xu explores the roles of genetic and cellular mechanisms, including the hedgehog pathway, FGF signaling, and epithelial-mesenchymal interactions, in driving lung fibrosis. Xu also highlights links between congenital diaphragmatic hernia (CDH) and lung development, suggesting that both mechanical and genetic factors contribute to lung hypoplasia. The discussion includes the development of advanced mouse models that replicate key aspects of human IPF, offering insights into fibrosis progression. Xu's research ultimately seeks to identify the causes of lung tissue abnormalities and pave the way for targeted therapies. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39460]

Scalable Sleep Biomarkers in Neurodevelopmental Disorders with Carrie Bearden - Autism Tree Annual Neurodiversity Conference 2024

Play Episode Listen Later Dec 16, 2024 34:02


Carrie Bearden, Ph.D., delves into how sleep patterns and brain activity influence memory and cognitive abilities in individuals with neurodevelopmental disorders, including autism. Her research reveals that while these individuals tend to sleep longer, their brain activity shows unique differences, such as reduced slow-wave power, which may limit the cognitive benefits typically associated with sleep. Bearden also spotlights groundbreaking studies using advanced tools like stem cells and brain organoids to investigate how specific genes might drive these differences, offering hope for deeper insights and potential interventions. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 40211]

Developing Microbiome-Directed Therapeutics for Treating Childhood Undernutrition

Play Episode Listen Later Dec 6, 2024 70:06


In this program, Dr. Jeffrey Gordon, Director of the Edison Family Center for Genome Sciences & Systems Biology at Washington University and the Scripps Institution of Oceanography's 2024 recipient of the Nierenberg Prize for Science in the Public Interest, discusses his research into the microbiome. Gordon is credited with founding the field of gut microbiome research. His transformative studies have demonstrated that human health and disease are shaped by the communities of microbes that live in the human gut. His body of work has opened up the vast new therapeutic potential for the microbiome, exemplified by his identification of ways to repair the gut microbiomes of children with malnutrition and restore their healthy growth. Series: "Science in the Public Interest" [Health and Medicine] [Show ID: 40154]

Harnessing My Daughter's Diagnosis to Drive Novel Treatments for Neurodevelopmental Disorders with Madeleine Oudin - Autism Tree Annual Neurodiversity Conference 2024

Play Episode Listen Later Dec 4, 2024 69:36


Madeline Oudin, Ph.D., is a scientist and mother on a groundbreaking mission to help her daughter, Margot, who has two de novo mutations in the SCN8A gene, which causes epilepsy. Margot's condition causes frequent seizures and developmental challenges. Determined to make a difference, Madeleine and her team are pioneering a cutting-edge genetic therapy that could one day transform treatment for Margot and others like her. In this heartfelt talk, Madeleine shares how her scientific expertise and personal journey intersect, revealing the highs and lows of developing life-changing treatments. From innovative approaches using Antisense Oligonucleotides (ASOs) to the unexpected success of a ketogenic diet, this story is about resilience, hope, and the power of community. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 40210]

Restoration of T Cell Development in CD3δ SCID Through Adenine Base-Editing with Gloria Yiu - Sanford Stem Cell Symposium 2024

Play Episode Listen Later Dec 2, 2024 28:12


Gloria Yiu, M.D., Ph.D., delves into the transformative potential of genetic editing technologies in addressing rare immune disorders, with a focus on CD3δ severe combined immunodeficiency (SCID)—a condition characterized by impaired T-cell development and severely compromised immune function. Leveraging her expertise as a physician-scientist, Yiu explores how CRISPR and other precision gene-editing tools can correct genetic mutations at the cellular level, potentially restoring T-cell production and immune resilience in patients with CD3δ SCID. Her presentation underscores the challenges and breakthroughs in treating such life-threatening conditions, emphasizing the role of interdisciplinary research, clinical innovation, and ethical considerations in advancing the frontiers of personalized medicine. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40245]

Infectious Disease Breakthroughs - Medicine Informing Novel Discoveries (MIND)

Play Episode Listen Later Nov 30, 2024 56:10


The infections disease landscape is constantly changing - challenging our standard treatments. Can new - as well as ancient - therapies be the answer? Hear from experts on the cutting edge of phage therapy, HIV/AIDS research and cancer care about what is on the horizon to improve human health. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39982]

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