Invasion of an organism's body tissues by disease-causing agents
POPULARITY
Categories
In this second half of our discussion with Dr. Erin McCreary and Dr. Hannah Creager, we dive deeper into how microbiology and antimicrobial stewardship teams collaborate to improve patient outcomes. They unpack how to prioritize breakpoint updates, the pros and cons of cascade reporting, and what nudges can do to guide better prescribing. Then we explore a powerful example of collaboration—the transition from MRSA agar to PCR across hospitals—and what it taught both teams about communication, resource sharing, and patient safety. Finally, Erin and Hannah reflect on lessons learned, first steps for building collaboration, and even share their favorite microbes (spoiler: both picked viruses!).
The Nobel Prize in physiology or medicine was awarded to three scientists for their work in immunology. Â Daniel Griffin, MD, PhD, Chief of Infectious Disease for Island Infectious Diseases, the largest physician-owned Infectious Disease Specialist Group on Long Island, an infectious disease specialist and clinical instructor of medicine at Columbia University and president of Parasites Without Borders and co-host of the podcast "This Week in Virology", explains their breakthrough and what it means for future treatments for autoimmune diseases, cancer, and more.Â
About this episode: For centuries, public health has seen invisible killers, believed in the power of community interventions, and created better health outcomes across the globe. In this episode: Former CDC director Tom Frieden explains how to tackle today's biggest health challenges and previews his new book, “The Formula for Better Health: How to Save Millions of Lives—Including Your Own”. Guest: Dr. Tom Frieden, MPH, is the president and CEO of Resolve to Save Lives. He previously served as the director of the CDC and is the author of “The Formula for Better Health: How to Save Millions of Lives—Including Your Own”. Host: Dr. Josh Sharfstein is distinguished professor of the practice in Health Policy and Management, a pediatrician, and former secretary of Maryland's Health Department. Show links and related content: The Formula for Better Health: How to Save Millions of Lives—Including Your Own—Penguin Random House A former CDC director's guide to seeing and stopping threats to America's health—STAT Transcript information: Looking for episode transcripts? Open our podcast on the Apple Podcasts app (desktop or mobile) or the Spotify mobile app to access an auto-generated transcript of any episode. Closed captioning is also available for every episode on our YouTube channel. Contact us: Have a question about something you heard? Looking for a transcript? Want to suggest a topic or guest? Contact us via email or visit our website. Follow us: @‌PublicHealthPod on Bluesky @‌JohnsHopkinsSPH on Instagram @‌JohnsHopkinsSPH on Facebook @‌PublicHealthOnCall on YouTube Here's our RSS feed Note: These podcasts are a conversation between the participants, and do not represent the position of Johns Hopkins University.
Are you one of the 52 million people in the U.S. who experience chronic pain daily? In It Doesn't Have to Hurt: Your Smart Guide to a Pain-Free Life, the practicing neurosurgeon and CNN's multiple Emmy Award-winning chief medical correspondent debunks the myth that most pain problems can only be fixed with a drug or procedure, and argues that we have agency with how to respond. In conversation with Dr. Anthony Fauci, the former Director of the National Institute of Allergy and Infectious Diseases at the NIH from 1984 to 2022. This program was held on September 11, 2025. Watch this conversation on YouTube.
The Minnesota Department of Health has confirmed 10 new cases of measles since Monday, bringing the total to 18 cases in the state. Meanwhile, national health officials reported there is a total of more than 1,500 cases across the country. That's the highest number since the disease was declared eliminated from the U.S. in 2000. Jessica Hancock-Allen, the director of the Infectious Disease Epidemiology, Prevention and Control Division at the Minnesota Department of Health, joined MPR News host Nina Moini to explain the situation.
Good communication isn't optional—it's essential for patient care. In Part 1 of this two-part series, Dr. Erin McCreary and Dr. Hannah Creager join Luis to talk about how microbiology labs and antimicrobial stewardship teams can collaborate more effectively. They share real-world examples from their system-wide work—aligning AST panels and breakpoints across multiple platforms, navigating reporting challenges like the clindamycin D-test and rifampin comments, and building consistent communication through monthly micro–stewardship meetings. It's a behind-the-scenes look at how strong collaboration turns into better patient outcomes.  Stay connected with Let's Talk Micro: Website: letstalkmicro.com Questions or feedback? Email me at letstalkmicro@outlook.com Support the podcast: Venmo Buy me a Ko-fi Â
Dr. Hoffman continues his conversation with Nicole Bell, the CEO of Galaxy Diagnostics and author of “What Lurks in the Woods.”Â
This episode of the Intelligent Medicine podcast is a deep dive into the complexities of Lyme disease and other tick-borne illnesses. Nicole Bell, the CEO of Galaxy Diagnostics and author of “What Lurks in the Woods,” details the challenges of diagnosing tick-borne diseases, the limitations of current diagnostic tests, and the controversy around treatment methodologies. Nicole shares her personal journey that led her to this field after her husband was misdiagnosed with early-onset Alzheimer's, which was later revealed to be caused by advanced Lyme disease. They also discuss new diagnostic techniques, the importance of personalized treatment plans, and ongoing advocacy efforts to improve awareness and research funding for Lyme disease.
On episode #90 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 9/12/25 – 9/24/25. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Crushed Bictegravir/Emtricitabine/Tenofovir Alafenamide (OFID) Tracking County-Level Measles Cases in the US (JAMA Nework) Tracking measles in US (Hopkins)  Pediatric influenza-associated encephalopathy and acute necrotizing encephalopathy (MMWR) Clinical recommendations for Lenacapivir (MMWR) Bacterial Primary oral vancomycin prophylaxis to stem an outbreak of Clostridioides difficile infection in intensive care patients (Antimicrob Steward Healthc Epidemiol) Clinical features and treatment strategies of Q fever spinal infection (OFID) Fungal Last of Us Season 2 The Pain is in the Brain (J Inf Dis) Parasitic Chagas Disease, an Endemic Disease in the United States (MMWR) Fixed-dose ivermectin for Mass Drug Administration (PLoS NTD) Outbreak of eosinophilic meningitis caused by the rat lungworm (Angiostrongylus cantonensis) in South Brazil (Am J Trop Med Hyg) Human monoclonal antibody MAM01 for protection against malaria in adults in the USA (Lancet Inf Dis) Permethrin-Treated Baby Wraps for the Prevention of Malaria (NEJM) Miscellaneous Ambient Documentation Technology in Clinician Experience of Documentation Burden and Burnout (JAMA Network Open) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
These diseases - West Nile Virus, Lyme disease, and Rocky Mountain Spotted Fever - are named for the places where outbreaks happened. But they're also all things you get from being bitten by mosquitoes or ticks. Research: Balasubramanian, Chandana. “Rocky Mountain Spotted Fever (RMSF): The Deadly Tick-borne Disease That Inspired a Hit Movie.” Gideon. 9/1/2022. https://www.gideononline.com/blogs/rocky-mountain-spotted-fever/ Barbour AG, Benach JL2019.Discovery of the Lyme Disease Agent. mBio10:10.1128/mbio.02166-19.https://doi.org/10.1128/mbio.02166-19 Bay Area Lyme Foundation. “History of Lyme Disease.” https://www.bayarealyme.org/about-lyme/history-lyme-disease/ Caccone, Adalgisa. “Ancient History of Lyme Disease in North America Revealed with Bacterial Genomes.” Yale School of Medicine. 8/28/2017. https://medicine.yale.edu/news-article/ancient-history-of-lyme-disease-in-north-america-revealed-with-bacterial-genomes/ Chowning, William M. “Studies in Pyroplasmosis Hominis.("Spotted Fever" or "Tick Fever" of the Rocky Mountains.).” The Journal of Infectious Diseases. 1/2/1904. https://archive.org/details/jstor-30071629/page/n29/mode/1up Elbaum-Garfinkle, Shana. “Close to home: a history of Yale and Lyme disease.” The Yale journal of biology and medicine vol. 84,2 (2011): 103-8. Farris, Debbie. “Lyme disease older than human race.” Oregon State University. 5/29/2014. https://science.oregonstate.edu/IMPACT/2014/05/lyme-disease-older-than-human-race Galef, Julia. “Iceman Was a Medical Mess.” Science. 2/29/2012. https://www.science.org/content/article/iceman-was-medical-mess Gould, Carolyn V. “Combating West Nile Virus Disease — Time to Revisit Vaccination.” New England Journal of Medicine. Vol. 388, No. 18. 4/29/2023. https://www.nejm.org/doi/full/10.1056/NEJMp2301816 Harmon, Jim. “Harmon’s Histories: Montana’s Early Tick Fever Research Drew Protests, Violence.” Missoula Current. 7/20/2020. https://missoulacurrent.com/ticks/ Hayes, Curtis G. “West Nile Virus: Uganda, 1937, to New York City, 1999.” From West Nile Virus: Detection, Surveillance, and Control. New York : New York Academy of Sciences. 2001. https://archive.org/details/westnilevirusdet0951unse/ Jannotta, Sepp. “Robert Cooley.” Montana State University. 10/12/2012. https://www.montana.edu/news/mountainsandminds/article.html?id=11471 Johnston, B L, and J M Conly. “West Nile virus - where did it come from and where might it go?.” The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses vol. 11,4 (2000): 175-8. doi:10.1155/2000/856598 Lloyd, Douglas S. “Circular Letter #12 -32.” 8/3/1976. https://portal.ct.gov/-/media/departments-and-agencies/dph/dph/infectious_diseases/lyme/1976circularletterpdf.pdf Mahajan, Vikram K. “Lyme Disease: An Overview.” Indian dermatology online journal vol. 14,5 594-604. 23 Feb. 2023, doi:10.4103/idoj.idoj_418_22 MedLine Plus. “West Nile virus infection.” https://medlineplus.gov/ency/article/007186.htm National Institute of Allergy and Infectious Disease. “History of Rocky Mountain Labs (RML).” 8/16/2023. https://www.niaid.nih.gov/about/rocky-mountain-history National Institute of Allergy and Infectious Disease. “Rocky Mountain Spotted Fever.” https://www.niaid.nih.gov/diseases-conditions/rocky-mountain-spotted-fever Rensberger, Boyce. “A New Type of Arthritis Found in Lyme.” New York Times. 7/18/1976. https://www.nytimes.com/1976/07/18/archives/a-new-type-of-arthritis-found-in-lyme-new-form-of-arthritis-is.html?login=smartlock&auth=login-smartlock Rucker, William Colby. “Rocky Mountain Spotted Fever.” Washington: Government Printing Office. 1912. https://archive.org/details/101688739.nlm.nih.gov/page/ Sejvar, James J. “West Nile virus: an historical overview.” Ochsner journal vol. 5,3 (2003): 6-10. https://pmc.ncbi.nlm.nih.gov/articles/PMC3111838/ Smithburn, K.C. et al. “A Neurotropic Virus Isolated from the Blood of a Native of Uganda.” The American Journal of Tropical Medicine and Hygiene. Volume s1-20: Issue 4. 1940. Steere, Allen C et al. “The emergence of Lyme disease.” The Journal of clinical investigation vol. 113,8 (2004): 1093-101. doi:10.1172/JCI21681 Steere, Allen C. et al. “Historical Perspectives.” Zbl. Bakt. Hyg. A 263, 3-6 (1986 ). https://pdf.sciencedirectassets.com/281837/1-s2.0-S0176672486X80912/1-s2.0-S0176672486800931/main.pdf World Health Organization. “West Nile Virus.” 10/3/2017. https://www.who.int/news-room/fact-sheets/detail/west-nile-virus Xiao, Y., Beare, P.A., Best, S.M. et al. Genetic sequencing of a 1944 Rocky Mountain spotted fever vaccine. Sci Rep 13, 4687 (2023). https://doi.org/10.1038/s41598-023-31894-0 See omnystudio.com/listener for privacy information.
This member-driven podcast is a benefit of membership of the Arizona Chapter of the American Academy of Pediatrics (AzAAP) and is intended for AzAAP pediatric healthcare members.AzAAP would like to acknowledge the generous support of the podcast by the Arizona Department of Health Services through the Title V Maternal and Child Health Services Block Grant funding. No information or content in this podcast is intended to substitute or replace a consultation with a healthcare provider or specialist. All non-healthcare providers should reach out to their child's pediatrician for guidance. Music: Wallpaper by Kevin MacLeodLink: https://incompetech.filmmusic.io/song/4604-wallpaperLicense: http://creativecommons.org/licenses/by/4.0/Â
About this episode: Last week, Dr. Debra Houry was testifying before Congress. Today, she's talking with Dr. Josh Sharfstein on Public Health On Call. In this episode: Dr. Houry reflects on her time at the CDC, the drastic changes at the agency under Health and Human Services Secretary Robert F. Kennedy Jr., and what she hopes her testimony can do to uphold quality public health. Guest: Dr. Debra Houry, MPH, most recently served as the Chief Medical Officer and Deputy Director for Program and Science at the CDC. She has also worked as a professor at both the Emory University School of Medicine and the Rollins School of Public Health, and as an emergency department physician. Host: Dr. Josh Sharfstein is distinguished professor of the practice in Health Policy and Management, a pediatrician, and former secretary of Maryland's Health Department. Show links and related content: Testimony from Debra Houry, M.D., M.P.H.—Senate Committee on Health, Education, Labor, and Pensions Senior CDC officials resign after Monarez ouster, cite concerns over scientific independence—CBS News A Brief Update: CDC in Crisis—Public Health On Call (September 2025) Transcript information: Looking for episode transcripts? Open our podcast on the Apple Podcasts app (desktop or mobile) or the Spotify mobile app to access an auto-generated transcript of any episode. Closed captioning is also available for every episode on our YouTube channel. Contact us: Have a question about something you heard? Looking for a transcript? Want to suggest a topic or guest? Contact us via email or visit our website. Follow us: @‌PublicHealthPod on Bluesky @‌JohnsHopkinsSPH on Instagram @‌JohnsHopkinsSPH on Facebook @‌PublicHealthOnCall on YouTube Here's our RSS feed Note: These podcasts are a conversation between the participants, and do not represent the position of Johns Hopkins University.
Kim Martin, Director of Infectious Diseases at ASTHO, recaps the recent ACIP meeting that took place and discusses the conversation's potential impacts on public health; Veronica Bryant, Emergency Preparedness and Outbreak Coordinator for the Environmental Health section of the North Carolina Department of Health and Human Services, shares how her state strengthened its extreme weather emergency preparedness following a series of hurricanes; on October 29th, ASTHO will host Part I of its new webinar series on how to enhance an environmental health response during extreme weather events; and ASTHO welcomes new member Dr. Mark McDaniel, State Health Officer for West Virginia. ASTHO Webinar: Weathering the Storm: The Importance of Environmental Health Preparedness and Response Part I CDC: Advisory Committee on Immunization Practices (ACIP) Mark McDaniel Bio Â
The Infectious Diseases Society of America (IDSA) has released new guidelines for the treatment of complicated urinary tract infections. In this episode, we break down the key updates: Changes to the definition of complicated UTIs The role of newer antibiotic agents How and when to use antibiograms A four-step framework for guiding therapy When carbapenems are necessary—and when other options may be just as effective Shorter durations of therapy Join Dr. Barbara Trautner, Dr. Nicolas Cortés-Penfield, and Dr. Kalpana Gupta as they discuss what these guidelines mean for clinicians, microbiologists, and patients.
Jim talks with an infectious disease expert. Plus - What is the car add-on you have to have? GUESTS: Dr. Angela Rasmussen - Principal Research Scientist, Vaccine and Infectious Diseases at the University of Saskatchewan
Guest: Leonard H. Calabrese, DO Preventing serious infections should be a priority when treating patients with immune-mediated inflammatory diseases, especially those receiving immunosuppressive therapies. By assessing patients' level of immunocompetence, clinicians can better tailor vaccination strategies and optimize infection prevention. Hear Dr. Leonard Calabrese discuss how to evaluate immunosuppression risk and coordinate timely vaccinations for patients undergoing immunomodulatory treatments. Dr. Calabrese heads the Section of Clinical Immunology at the Cleveland Clinic in Ohio, where he manages the Clinical Immunology Clinic and is on the staff of the Department of Rheumatic and Immunologic Diseases. He also spoke on this topic at the 2025 Congress of Clinical Rheumatology West conference.
The guest host for today's show is Brad Bannon. Brad runs Bannon Communications Research, a polling, message development and media firm which helps labor unions, progressive issue groups and Democratic candidates win public affairs and political campaigns. His show, 'Deadline D.C. with Brad Bannon,' airs every Monday from 3-4pm ET. Brad is first joined by Kate Ackley, a Senior Reporter for Bloomberg Government. The two examine the impending government shutdown, which is set to happen October 1st. Democrats seem less eager to bail out Republicans than they did at the beginning of the current Trump administration, drawing the line at new massive healthcare cuts which would drive up premiums 10-20% for folks with Affordable Care Act health plans. Then, Brad is joined by Dr. Bob Bollinger is the Raj and Kamla Gupta Professor of Infectious Diseases at the Johns Hopkins University School of Medicine. They examine the chaos caused at the CDC by RFK Jr. and the Trump administration, and the potentially dangerous new restrictions on who can now receive vaccines.  Dr. Bollinger holds joint appointments in International Health at the Johns Hopkins Bloomberg School of Public Health, and in Community Public Health at the JH School of Nursing. He has more than 45 years of experience in international public health, clinical research, and education dealing with such global health priorities as HIV/AIDS, malaria, tuberculosis, leprosy, dengue, antibiotic resistant infections, COVID-19 and other emerging diseases. Dr. Bollinger is also Associate Director of the Center for Clinical Global Health Education (CCGHE). Their website is main.ccghe.net. Brad writes a political column every Sunday for 'The Hill.' He's on the National Journal's panel of political insiders and is a national political analyst for WGN TV and Radio in Chicago and KNX Radio in Los Angeles. You can read Brad's columns at www.MuckRack.com/Brad-Bannon. His handle on BlueSky is @bradbannon.bsky.social. Â
The guest host for today's show is Brad Bannon. Brad runs Bannon Communications Research, a polling, message development and media firm which helps labor unions, progressive issue groups and Democratic candidates win public affairs and political campaigns. His show, 'Deadline D.C. with Brad Bannon,' airs every Monday from 3-4pm ET. Brad is first joined by Kate Ackley, a Senior Reporter for Bloomberg Government. The two examine the impending government shutdown, which is set to happen October 1st. Democrats seem less eager to bail out Republicans than they did at the beginning of the current Trump administration, drawing the line at new massive healthcare cuts which would drive up premiums 10-20% for folks with Affordable Care Act health plans. Then, Brad is joined by Dr. Bob Bollinger is the Raj and Kamla Gupta Professor of Infectious Diseases at the Johns Hopkins University School of Medicine. They examine the chaos caused at the CDC by RFK Jr. and the Trump administration, and the potentially dangerous new restrictions on who can now receive vaccines.  Dr. Bollinger holds joint appointments in International Health at the Johns Hopkins Bloomberg School of Public Health, and in Community Public Health at the JH School of Nursing. He has more than 45 years of experience in international public health, clinical research, and education dealing with such global health priorities as HIV/AIDS, malaria, tuberculosis, leprosy, dengue, antibiotic resistant infections, COVID-19 and other emerging diseases. Dr. Bollinger is also Associate Director of the Center for Clinical Global Health Education (CCGHE). Their website is main.ccghe.net. Brad writes a political column every Sunday for 'The Hill.' He's on the National Journal's panel of political insiders and is a national political analyst for WGN TV and Radio in Chicago and KNX Radio in Los Angeles. You can read Brad's columns at www.MuckRack.com/Brad-Bannon. His handle on BlueSky is @bradbannon.bsky.social.  (Image Credit: Jabin Botsford/The Washington Post/Getty Images)
Jame is joined by Chloe from BioMerieux to discuss clinical decision support systems and their application in Microbiology & Infectious Disease! What are they, how do they work, and what are the potential applications in antimicrobial stewardship? Listen on for details! Note: This episode was produced in collaboration with BioMérieux. An honorarium received from them will be donated directly to charitable causes.Message from BioMérieux: Every effort has been made to ensure the accuracy of information shared during our podcast appearances. The views expressed by our representatives are in good faith and based on the information available at the time. We accept no liability for any errors, omissions, or discrepancies. For the most accurate and up-to-date product details, please refer to our official website or contact us directlySend us a text Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.socialPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod
Welcome back to Dr. M's Women & Children First, where we explore the front lines of children's health and what matters most for our families. Today I'm honored to bring you Dr. Paul A. Offit, the Director of the Vaccine Education Center and Professor of Pediatrics in the Division of Infectious Diseases at Children's Hospital of Philadelphia. He also holds the Maurice R. Hilleman Professorship of Vaccinology at the University of Pennsylvania. Dr. Offit is a globally recognized expert in virology and immunology. He has served on the CDC's Advisory Committee on Immunization Practices and FDA's Vaccines and Related Biological Products Advisory Committee. He's co-editor of the seminal vaccine textbook Vaccines, and for decades has been one of the clearest scientific voices defending evidence, transparency, and children's health. This week, we'll dig into COVID, vaccine policy, and what's ahead for children in light of the latest shifts. Among current headlines: Healthy children and pregnant women are no longer being uniformly recommended for COVID vaccines by Health Secretary Robert F. Kennedy Jr., a decision that's stirring debate among pediatricians and public health experts like Dr. Offit. He's sharply voiced concerns about removing key vaccine recommendations without new data, and about the broader implications of loosening vaccine guidance for the public good. In this conversation, we'll cover: What the science says now about bivalent COVID vaccines in kids How recent policy changes affect vaccine access, trust, and safety What parents need to know—what's changed, what's stable, and what remains uncertain This is my third time talking with Dr. Offit, and as always, I expect you'll leave with clarity, evidence, and questions worth sharing. I hope you enjoy this conversation. Let's dive in. Dr. M
In this second-ever collaboration between SIDP's Breakpoints and ESCMID's Communicable podcasts, hosts Erin McCreary and Angela Huttner invite the two principal investigators and visionaries who spearheaded the Bacteraemia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE) trial, Nick Daneman and Rob Fowler (Sunnybrook Health Sciences Centre, Toronto), for a “deep dive into all things that went into this trial” (1). The BALANCE trial spanned over ten years investigating - as the acronym title suggests - whether a shorter treatment duration of seven days was non-inferior to the standard of care of fourteen days for bacteraemia. The conversation covers everything from the initial hallway discussions that sparked the trial to the trial itself that screened over 36,000 patients and enrolled +3,600, its key takeaways and its impact on clinical practice as well as what's next for Daneman and Fowler.This episode was edited by Kathryn Hostettler and Megan Klatt, and peer reviewed by Dr. Arjana Zerja of Mother Theresa University Hospital Centre, Tirana, Albania.Related podcast episodesCommunicable episode 36: Finding BALANCE in antibiotic durations—the BALANCE trial https://share.transistor.fm/s/b680895eCommunicable episode 26: SNAP out of it—rethinking anti-staphylococcal penicillins for S. aureus bacteremia, the SNAP trial PSSA/MSSA results https://share.transistor.fm/s/2a3c3bb4Breakpoints episode covering IDWeek (December 2024) https://breakpoints-sidp.org/108-idweek-2024-recap-late-breaker-abstracts-and-stewardship-talks/ ReferencesBALANCE Investigators, et al. Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections. N Engl J Med. 2025 March. DOI: 10.1056/NEJMoa2404991Further reading Fowler VG. Eight days a week – BALANCING duration and efficacy. N Engl J Med. 2025 March. DOI: 10.1056/NEJMe2414037  Dulhunty JM, et al. Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients With Sepsis: The BLING III Randomized Clinical Trial. JAMA 2024. DOI: 10.1001/jama.2024.9779  Yahav D, et al. Seven versus 14 days of antibiotic therapy for uncomplicated Gram-negative bactermia: A noninferiority randomized controlled trial. Clin Infect Dis 2018. DOI: 10.1093/cid/ciy1054 Von Dach E, et al. Effect of C-reactive protein-guided antibiotic treatment duration, 7-day treatment, or 14-day treatment on 30-day clinical failure rate in patients with uncomplicated Gram-negative bacteremia, a randomized clinical trial. JAMA 2020. DOI: 10.1001/jama.2020.6348 Ong SWX, et al. Identifying heterogeneity of treatment effect for antibiotic duration in bloodstream infection: an exploratory post-hoc analysis of the BALANCE randomised clinical trial. EClinicalMedicine 2025. DOI: 10.1016/j.eclinm.2025.103195Wallach JD, et al. Evaluation of evidence of statistical support and corroboration of subgroup claims in randomized clinical trials. JAMA Intern Med 2017. DOI: 10.1001/jamainternmed.20169125
Host: Peter Buch, MD, FACG, AGAF, FACP Guest: Yinghong Wang, MD, PhD, MS Immune checkpoint inhibitor (ICI) colitis comes with unique diagnostic and treatment challenges, which means that recognizing and managing it effectively is key to the best outcomes. Joining Dr. Peter Buch to share her insights on caring for patients with this complex condition is Dr. Yinghong Wang. Dr. Wang is a Professor in the Department of Gastroenterology, Hepatology, and Nutrition at MD Anderson Cancer Center in Houston, Texas, as well as Director of the Oncology-GI Toxicity Program, Director of Fecal Microbiota Transplantation, Deputy Division Head of Research in the Division of Internal Medicine, and Chair of the MD Anderson Cancer Center Immunotherapy Toxicity Working Group.
Shalini Nair, Senior Analyst of Infectious Disease at ASTHO, tells public health professionals everything they need to know about New World Screwworm (NWS), and what to do if their state experiences a case; Maggie Nilz, Senior Analyst of Preparedness at ASTHO, shares information from a new Health Policy Update on public health preparedness for extreme weather events; up to four states have the opportunity to host a two-day, in-person wastewater surveillance training opportunity, and the deadline to apply is September 19th; the latest edition of the DELPH Magazine is out, providing health officials with new information about the Developing Executive Leaders in Public Health program; and next Thursday, September 25th at 2:00 p.m. ET is the second session of the Activate series in the Ignite, Accelerate and Activate workshop, which will focus on improving emotional intelligence.  ASTHO Blog: New World Screwworm Insights and Action Steps ASTHO Health Policy Update: State Policy Advances in Extreme Weather Preparedness ASTHO Web Page: Ethical Analysis for Infectious Disease Wastewater Surveillance Training Opportunity ASTHO Web Page: DELPH Magazine ASTHO Webinar: Ignite, Accelerate, and Activate: Series 3, Session 2: Improving Emotional Intelligence Â
Bloodstream infections can progress rapidly to sepsis—bringing high costs, high mortality, and lasting effects. In the second episode of this series in collaboration with bioMĂ©rieux, Luis speaks with Dr. Jeff Cies, Senior Medical Advisor at bioMĂ©rieux, about how molecular diagnostics are reshaping bloodstream infection diagnosis. They discuss: Limitations of traditional blood cultures How rapid molecular tests deliver results faster than ever The impact on outcomes, costs, and antimicrobial resistance The role of stewardship programs in maximizing results What the future holds: direct-from-blood testing, nanotechnology, and AI A powerful look at how innovation in microbiology is changing the fight against sepsis and saving lives. This episode is sponsored by bioMĂ©rieux, a global innovator in infectious disease diagnostics. Resources from this episode: bioMĂ©rieux Sepsis Webinar Stay connected with Let's Talk Micro: Website: letstalkmicro.com Questions or feedback? Email me at letstalkmicro@outlook.com Support the podcast: Venmo Buy me a Ko-fi Â
Brooke Gladstone speaks with Paul Offit, the director of the Vaccine Education Center and a physician in the Division of Infectious Diseases at Children's Hospital of Philadelphia, about how the Secretary of Health and Human Services, Robert F. Kennedy Jr., purged the CDC's vaccine advisory committee members, the controversial figures Kennedy replaced them with, and what impact this will have on the future of vaccines and immunology in the US. On the Media is supported by listeners like you. Support OTM by donating today (https://pledge.wnyc.org/support/otm). Follow our show on Instagram, Twitter and Facebook @onthemedia, and share your thoughts with us by emailing onthemedia@wnyc.org.
On episode #89 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 8/18/25 – 9/11/25. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Antibody Responses are Sustained 2 Years Post-Mpox Infection but not Following Modified Vaccinia Ankara–Bavarian Nordic Vaccination (OFID) Intestinal mucosal immune responses to novel oral poliovirus vaccine type 2 in healthy newborns (CID) Efficacy of Baloxavir Treatment in Preventing Transmission of Influenza (NEJM) Fulminant Viral Myocarditis Associated with Thogotovirus (NEJM) Bacterial Risk factors for 30-Day mortality and the role of empirical therapy in Pseudomonas aeruginosa bloodstream infections(Infection) The Impact of a Nationwide Blood Culture Bottle Shortage in 2024 on Healthcare Facilities in the United States (CID) The effect of commonly used non-antibiotic medications on antimicrobial resistance development in Escherichia coli(NPJ: antimicrobials and resistance) Preoperative Enterosignatures Predict Surgical Site Infections After Abdominal Surgery (OFID) Fungal The Last of US Season 2 (YouTube) Association between Duration of Candidemia and Clinical and Healthcare Resource Utilization Outcomes among Hospitalized Adult Patients with Candidemia Who Received Empiric Treatment with an Echinocandin Across United States Hospitals (CID) Updating the epidemiology of blastomycosis and histoplasmosis in the United States, using national electronic health record data, 2013–2023 (JID) Parasitic Stocking African catfish in Lake Victoria provides effective biocontrol of snail vectors of Schistosoma mansoni (PLoS Neglected Tropical Disease) Miscellaneous Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
In this important episode of Transmission Interrupted, host Jill Morgan is joined by a distinguished panel of experts to provide a comprehensive update on respiratory illness trends for the 2025 season. Dr. Ryan Maves (infectious diseases and critical care medicine, Wake Forest University), Dr. Kari Simonson (pediatric infectious diseases, University of Nebraska Medical Center), and Dr. John Horton (clinical affairs, gynecology and obstetrics, Emory University) share the latest data and evidence-based recommendations for healthcare providers and the public.The discussion covers the full spectrum of respiratory viruses currently impacting our communities, including influenza, RSV, COVID-19, and pertussis. The panel addresses the unique risks facing infants, children, pregnant individuals, older adults, and those with underlying health conditions. Listeners will gain valuable insight into current vaccine guidance, the role of updated testing strategies, and protective measures that go beyond vaccination—such as proper mask use, respiratory and hand hygiene, and the importance of source control and eye protection.This episode offers practical guidance for both healthcare workers and the public as we enter another busy respiratory virus season. Drawing on real-world experience and the latest research, our guests emphasize steps we can all take to reduce transmission, protect vulnerable populations, and maintain safety in both clinical and home settings.GuestsJohn Patrick Horton, MD, MBAVice Chair of Clinical Affairs for Gynecology and Obstetrics Emory UniversityDr. John Horton is the Vice Chair of Clinical Affairs for Emory University's Department of Gynecology and Obstetrics. He also serves as Emory Healthcare's Division Director for General Gynecology and Obstetrics, and Interim Operations Director for the Gynecologic Specialties Division. Additionally, Dr. Horton is the Director of the Obstetric Rapid Response Team at Emory Healthcare and is Associate Professor at the Emory University School of Medicine Department of Gynecology and Obstetrics. Ryan Maves, MD, FCCM, FCCP, FIDSAProfessor in Infectious Disease and Critical Care MedicineOffice of Global HealthWake Forest UniversityDr. Ryan Maves is a Professor of Medicine at the Wake Forest University School of Medicine in Winston-Salem, North Carolina, where he serves as medical director of transplant infectious diseases and as a faculty intensivist at North Carolina Baptist Hospital. A graduate of the University of Washington School of Medicine, he entered active duty in the U.S. Navy in 1999. He completed his residency in internal medicine and fellowships infectious diseases and critical care medicine at Naval Medical Center San Diego. During his military service, he served as the flight surgeon for Carrier Air Wing SEVENTEEN embarked onboard the USS George Washington (CVN-73), at the Naval Medical Research Unit No. 6 in Lima, Peru, conducting preclinical and clinical studies in antimicrobial drug resistance and vaccine development, as director of medical services at the NATO Role 3 Multinational Medical Unit at Kandahar Airfield, Afghanistan, and as ID division chief and fellowship director in San Diego. He retired from active duty in 2021 and joined the faculty at Wake Forest. He is the chair of the ABIM Critical Care Medicine Examination Board, co-chair of the SCCM Congress Program Committee, and Chair-Elect of the Chest Infections and Disaster Response Network in CHEST, as well as deputy editor for outreach for the journal CHEST and contributing editor for Critical Care Explorations. He is an author of over 150 scientific manuscripts, 15 textbook chapters, and 100 conference abstracts and invited lectures. He lives in Winston-Salem with his wife, Robin, whom he met in the traditional manner (in the ICU, next to a...
Dr. Ravi Kamepalli made a startling realization that changed everything: bacteria aren't the enemy. As both an infectious disease specialist and wound care physician, he witnessed firsthand how traditional medicine's war on microbes was failing patients catastrophically. In this profound conversation, he unveils his revolutionary "disease triangles" framework that connects our immune system, lipid metabolism, and microbiome in ways that transform how we understand healing.The statistics he shares will shock you: diabetic foot amputations have a higher five-year mortality rate than breast cancer. While diabetes costs healthcare systems $237 billion annually compared to cancer's $80 billion, we're attacking symptoms instead of root causes. Dr. Kamepalli explains his concept of "energy toxicity" - how excess stored energy triggers inflammatory cascades that turn our own immune systems against us.Through his personal journey of losing 50 pounds and dramatically reducing his LP(a) levels, he demonstrates that supposedly "genetic" markers are actually nutritionally modifiable. His approach integrates metabolic interventions with wound care, using continuous glucose monitoring, food logging, and remote patient tracking to address the underlying metabolic dysfunction that prevents healing.This isn't just about wound care - it's about reimagining medicine itself. Dr. Kamepalli advocates for moving beyond "mass medicine mindset" toward personalized, n-of-one healthcare that empowers patients with tools, tracking, and understanding rather than simply prescribing interventions. His vision extends from revolutionizing American healthcare to building sustainable systems in rural India.BIG IDEA"We cannot kill bacteria and keep the humans alive - we need to learn how to survive together, and that survival depends on fixing our metabolic dysfunction, not declaring war on microbes."Dr. Ravi Kamepalli Contact InfoWebsite: https://nobadbugs.com/Social Media: @WoundPhysicianWebsite: ColigoMed.comSociety for Metabolic Health Practitioners SMHP.orgSend Dr. Ovadia a Text Message. (If you want a response, you must include your contact information.) Dr. Ovadia cannot respond here. To contact his team, please send an email to team@ifixhearts.com Like what you hear? Head over to IFixHearts.com/book to grab a copy of my book, Stay Off My Operating Table. Ready to go deeper? Talk to someone from my team at IFixHearts.com/talk.Stay Off My Operating Table on X: Dr. Ovadia: @iFixHearts Jack Heald: @JackHeald5 Learn more: Stay Off My Operating Table on Amazon Take Dr. Ovadia's metabolic health quiz: iFixHearts Dr. Ovadia's website: Ovadia Heart Health Jack Heald's website: CultYourBrand.com Theme Song : Rage AgainstWritten & Performed by Logan Gritton & Colin Gailey(c) 2016 Mercury Retro RecordingsAny use of this intellectual property for text and data mining or computational analysis including as training material for artificial intelligence systems is strictly prohibited without express written consent from Dr. Philip Ovadia.
Sally and I chat to Infectious Diseases consultant Peter Simos and regular, senior pharmacist, Dan Adams about the role of the Infectious diseases team, antibiotic stewardship and the take home key points about the use of antibiotics. We hope you enjoy
On Monday's show: We preview this week's vote on the Harris County budget. The budget process this year has often been contentious as tensions rise over funding cuts.Also this hour: Dr. Peter Hotez of Baylor College of Medicine discusses his book, Science Under Siege, which examines growing opposition to science and the threat it poses.Then, veterinarian Dr. Lori Teller answers listeners' questions about their pets.And Jeff Balke previews a season-defining week ahead for the Astros and the Monday Night Football matchup between the Texans and the Buccaneers. Watch
Brucella is a familiar name in the lab—but recent updates to the sentinel guidelines are reshaping how we approach this pathogen. In this episode, I'm joined by Dr. Laura Filkins and Dr. Paige Larkin to discuss the latest changes: updates in nomenclature, the removal of certain Brucella species from the select agent list, and the renewed emphasis on safety in the lab. We dive into taxonomy controversies, clinical features of brucellosis, and practical steps laboratorians can take to protect themselves while delivering accurate results. Whether you're a student, laboratorian, or clinician, this conversation highlights what you need to know about the evolving landscape of Brucella diagnostics and safety.  Resources from this episode: CDC's Brucellosis Information Page ASM Updates on Brucella Stay connected with Let's Talk Micro: Website: letstalkmicro.com Questions or feedback? Email me at letstalkmicro@outlook.com Support the podcast: Venmo Buy me a Ko-fi Â
Darshali Vyas is a pulmonary and critical care fellow at Massachusetts General Hospital. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. D.A. Vyas, L.G. Eisenstein, and D.S. Jones. The Race-Correction Debates — Progress, Tensions, and Future Directions. N Engl J Med 2025;393:1029-1036.
 Ever since the world was overtaken by the COVID-19 pandemic, public health policy and vaccine policy have been front and center in the national political debate. And tragically, despite a longstanding and overwhelming consensus among public health experts across the globe about the efficacy of vaccines and their vital importance in protecting human health […]
On this week's How on Earth, Beth describes recent developments in defunding NIH research and CDC limits on vaccine availability; then digs into vaccine safety and development with global vaccine expert, Dr Dr Kawsar Talaat. Dr Talaat is a physician who is board certified in Pediatrics, Internal Medicine and Infectious Diseases and whose research focuses … Continue reading "The (ever-changing) Scoop on Vaccines"
Dr. Arti Barnes, Chief Medical Officer at the Illinois Department of Public Health, describes how her agency is working collaboratively with other state departments to enhance access to pediatric vaccinations; Jeffrey Ekoma, Senior Director of Government Affairs at ASTHO, discusses changes to the CDC, this month's federal funding deadline, and more news from Capitol Hill in this week's View From Washington, D.C. report; a full-length recording of ASTHO's webinar on Navigating Ethical Issues in Wastewater Surveillance for Infectious Diseases is now available online; and ASTHO congratulates new member Dr. John Dunn on his appointment as Interim Commissioner for the Tennessee Department of Health. ASTHO Newscast: 925: KFF Tracking Poll, Youth Vaccines ASTHO Legislative Alert: Summary of FY26 House LHHS Appropriations Bill ASTHO Web Page: INSPIRE: Readiness - Navigating Ethical Issues in Wastewater Surveillance for Infectious Diseases John Dunn Bio Â
Dr Irene Grant is an Infectious Disease specialist with expertise in infectious complications in the immunocompromised and unusual infections in the immunocompetent. In the 1980's, in the midst of the HIV/AIDS epidemic, she trained at Memorial Sloan-Kettering Cancer Center in New York City, under Dr. Donald Armstrong (former President of the Infectious Disease Society of America) where she acquired training in Microbiology and Hospital Infection Control. Thereafter she spent years in academic medicine as an Assistant Professor of Medicine at Albert Einstein College of Medicine (1988 – 2000) and later Clinical Assistant Professor of Medicine at New York Medical College, involved in teaching, clinical epidemiology, and research, while treating inner city patients in the HIV “epicenter” in the Bronx. Later, in private practice, she applied her experience investigating unusual illnesses to help her patients sick from hazardous indoor exposures. For the past 24 years, she has evaluated and treated hundreds of debilitated patients and families with environmentally proven hazardous microbial exposures, correlating the development of multi-system illness with hazardous exposures, the reliability of diagnostic tests, and efficacy of anti-fungal treatment.
Antimicrobial resistance (AMR) continues to grow as a global health threat, making infections harder to treat and leaving fewer options for patients. The need for new antibiotics is an urgent matter — but traditional discovery methods are slow and limited. In this episode of Let's Talk Micro, Luis is joined by Dr. James Collins, professor at MIT and researcher at the Broad Institute, who is leading efforts to apply AI to antibiotic discovery. We discuss how his team used deep learning to uncover promising new compounds, including NG1 and DN1, which showed activity against drug-resistant Neisseria gonorrhoeae and Staphylococcus aureus. We also talk about the challenges of bringing discoveries from computer models to the clinic, and what this approach could mean for the future of the fight against superbugs.  Link to study: https://www.cell.com/cell/abstract/S0092-8674%2825%2900855-4  Check out the website: https://www.letstalkmicro.com/ Questions? Feedback? Send those to letstalkmicro@outlook.com Want to support the podcast? Here's how: Venmo: https://venmo.com/u/letstalkmicro Buy me a Ko-fi: https://ko-fi.com/letstalkmicro Â
Send us a textIn this inspiring episode, Anne E. Goldfeld, MD—physician-scientist, humanitarian, and recipient of the 2025 Jimmy and Rosalynn Carter Humanitarian Award—joins Marla Dalton, CAE, and William Schaffner, MD, to reflect on a remarkable career in medicine, science, and global health. From treating patients in refugee camps along the Thai-Cambodian border to conducting groundbreaking research at Harvard Medical School and Boston Children's Hospital, Goldfeld shares the path that led her to a career that is tackling 2 of the greatest epidemics of our time: tuberculosis and HIV/AIDS.Show NotesA native Californian, Dr. Goldfeld attended Brown University and the University of California, Berkeley, and earned her medical degree from Albert Einstein College of Medicine. She completed her internship and residency in internal medicine and a clinical fellowship in infectious diseases at the Massachusetts General Hospital followed by a postdoctoral research training in molecular biology at Harvard University. She is Professor of Medicine and Pediatrics at Harvard Medical School and a Senior Investigator in the Program in Cellular and Molecular Medicine at Boston Children's Hospital, where her research laboratory is located. She is also Professor of Immunology and Infectious Disease at the Harvard TH Chan School of Public Health and a physician in the infectious disease division of Brigham and Women's Hospital. On the frontlines of the TB and AIDS crises, Dr. Goldfeld co founded transformative treatment and research programs—bringing care to some of the world's most underserved populations—that have led to fundamental discoveries that have saved countless lives.Follow NFID on social media
Guest: Francis Farraye, MD Host: Peter Buch, MD, FACG, AGAF, FACP A 2025 update to the American College of Gastroenterology (ACG)'s guideline on preventive care in inflammatory bowel disease (IBD) includes key changes impacting vaccine recommendations, dermatologic screening, and care coordination. Dr. Peter Buch sits down with Dr. Francis Farraye, lead author of this guideline, to highlight what clinicians need to know. Dr. Farraye is a Professor of Medicine and the Director of the Inflammatory Bowel Disease Center at the Mayo Clinic in Jacksonville, Florida
On episode #88 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 8/19/25 – 8/27/25. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Respiratory Syncytial Virus Immunization Coverage Among Infants Through Receipt of Nirsevimab Monoclonal Antibody or Maternal Vaccination (CDC: MMWR) Bictegravir, emtricitabine, and tenofovir alafenamide versus ritonavir-boosted protease inhibitor-based antiretroviral therapy in people with HIV and viral suppression on second-line therapy in Haiti: an open-label, randomised, non-inferiority trial (LANCET: HIV) Interferon-α Nasal Spray Prophylaxis Reduces COVID-19 in Cancer Patients: A Randomized, Double-Blinded, Placebo-Controlled Trial (CID) Bacterial Exposure to suppressive antibiotic therapy in women with recurrent urinary tract infections and severity of infections: a retrospective population-based cohort study (BMJ Open) Effectiveness and safety of antibiotics in kidney transplant recipients with asymptomatic bacteriuria: a systematic review and meta-analysis of randomized controlled trials (OFID) Epidemiological, temporal, and geographic trends of leptospirosis in the United States, 2014–2020 (PLoS Neglected Tropical Diseases) Performance of Tongue Swabs for Tuberculosis Diagnosis in Hospitalized Children Under 5 Years of Age (OFID) Fungal The Last of US Season 2 (YouTube) Towards shorter therapy for candidaemia: defining uncomplicated candidaemia in adults (LANCET: Infectious Diseases) Parasitic Outcomes of Military Blood Donors at Joint Base San Antonio with Reactive Trypanosoma cruzi Antibody Screening (OFID) Cutaneous acanthamoebiasis: Two Cases Highlighting Diverse Histopathologic Findings (Journal of Cutaneous Pathology) Miscellaneous Linezolid-related Optic Nerve Disorders: Insight from a Pharmacovigilance Analysis of the U.S. FDA Adverse Event Reporting System (OFID) Extreme variability in linezolid concentrations in the ICU: A case for routine therapeutic drug monitoring (American Journal of Health-System Pharmacy) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
The germ theory of disease is one of the greatest breakthroughs in human history. But it took more than 2,000 years of false starts and resistance before medicine finally recognized that germs cause disease. In his book Germ Theory, Dr. Robert Gaynes unpacks why this shift was so hard to achieve. In this episode, he and Dart explore what it teaches us about paradigm shifts today: why new ideas face such resistance, how the personalities of innovators influence acceptance, and what happens when a powerful new paradigm leads us to overcorrect.Dr. Robert P. Gaynes is an infectious disease physician and Professor of Medicine at Emory University. He is the author of Germ Theory, a CHOICE Outstanding Academic Title.In this episode, Dart and Robert discuss:- Why it took centuries to accept that germs cause disease- What resistance to handwashing reveals about change- Breakthroughs Robert witnessed in his career- How medicine's history reveals patterns of change- HIV's transformation from fatal to treatable- What happens when new paradigms go too far- How personality shapes whether innovations are accepted- Lessons for anyone driving change at work today- And other topics…Dr. Robert P. Gaynes is an infectious disease physician and Professor of Medicine at Emory University. He chairs Emory's Infection Control and Antimicrobial Stewardship Committees, attends at the Atlanta VA Medical Center, and has written extensively on hospital-acquired infections and antimicrobial use. He is the author of Germ Theory: Medical Pioneers in Infectious Disease, named a CHOICE Outstanding Academic Title.Resources Mentioned:Germ Theory: Medical Pioneers in Infectious Disease by Robert Gaynes: https://www.amazon.com/Germ-Theory-Pioneers-Infectious-Diseases/dp/168367376XGet discounted tickets to the Responsive Conference, featuring past Work for Humans guests Bree Groff and Simone Stolzoff – September 17–18, Oakland, CA. Use code “11fold”: https://www.responsiveconference.com/ticketsRegister to attend the UWEBC Conference, where Dart keynotes the HR track alongside Ethan Mollick and Nancy Giordano – September 30, University of Wisconsin: https://uwebc.wisc.edu/conference/registration/Connect with Robert:LinkedIn: https://www.linkedin.com/in/robert-p-gaynes-49b1541/Work with Dart:Dart is the CEO and co-founder of the work design firm 11fold. Build work that makes employees feel alive, connected to their work, and focused on what's most important to the business. Book a call at 11fold.com.
Legionella remains one of the most complex challenges for water professionals worldwide. How do we balance effective monitoring with realistic costs—and which strategies deliver true public health impact? In this episode, Trace Blackmore welcomes Dr. Vincenzo Romano Spica,  Head Public Health University of Rome "Foro Italico to explore new insights from his comparative research on Legionella control. Reframing Legionella Risk Dr. Spica explains why public health data increasingly points to Legionella pneumophila—not all Legionella species—as the primary concern for human health. He shares how pan-European data modeling and peer-reviewed studies demonstrate that broad-spectrum monitoring may overburden systems without delivering proportional safety gains. Cost-Benefit Models and Sustainability Water professionals know that testing and compliance require resources. Dr. Spica discusses cost-benefit analysis frameworks that help decision-makers evaluate where investments deliver the greatest reduction in risk. He also highlights the sustainability implications of over-testing, from lab resources to environmental waste streams. European Regulations and Legal Liability The conversation also explores the European Drinking Water Directive 2020/2184, national approaches to Legionella, and how liability shifts when contamination is detected. Dr. Spica's insights illuminate what building owners, operators, and regulators must weigh as they update management plans. Conclusion For engineers, operators, and technical managers, this episode provides a clear framework for thinking about Legionella beyond routine testing. It's about focusing on the pathogen that truly drives disease outcomes, aligning regulatory strategy with science, and applying resources where they matter most. Stay engaged, keep learning, and continue scaling up your knowledge!  Timestamps   02:24 - Trace opens the episode, welcoming listeners to Legionella Awareness Month and framing the call to action 05:37 - Water You Know with James McDonald 10:04 - Upcoming Events for Water Treatment Professionals  14:06 - Trace introduces Dr. Vincenzo Romano Spica, Head of Public Health at the University of Rome Foro Italico  17:22 - Dr. Spica outlines why Legionella pneumophila is the main pathogen of concern in Europe 35:04 - Dr. Spica explains Disability Adjusted Life Years (DALYs) as a measure of public health burden 44:08 - Monitoring strategies and how different culture methods affect outcomes 46:16 - The role of water temperature in Legionella proliferation  Quotes “Not all Legionella are equal—public health data shows us it's Legionella pneumophila that drives the real risk.” “Testing everything may look safer on paper, but in practice, it diverts resources from where they can have the greatest impact.” “Risk management should not be a checklist; it should be a strategic allocation of resources aligned with outcomes.” “European data models show that a targeted approach can deliver both better safety and greater sustainability.”  Connect with Dr. Vincenzo Romano Spica  Phone: +39.06.36733247 Email: vincenzo.romanospica@uniroma4.it LinkedIn: vincenzo romano spica | LinkedIn    Guest Resources Mentioned  Legionnaires' Disease Surveillance and Public Health Policies in Italy: A Mathematical Model for Assessing Prevention Strategies by Dr. Spica et. al Alessando Cassini's Burden of Infectious Diseases in Europe methodological challenges and opportunities for public health policy NLM's Impact of infectious diseases on population health using incidence-based disability-adjusted life years (DALYs): results from the Burden of Communicable Diseases in Europe study, European Union and European Economic Area countries, 2009 to 2013 Supplemental information: Impact of UAT Diagnostic Methods on Estimates of Legionnaires' disease Caused by non-pneumophila Legionella  Scaling UP! H2O Resources Mentioned AWT (Association of Water Technologies) Scaling UP! H2O Academy video courses Submit a Show Idea Scaling UP! H2O's Legionella Resources Library 434 Encore Interview with Patsy Root  Water You Know with James McDonald Question: What is it called when a valve is closed at the end of a pipeline system causing a pressure wave to propagate in the pipe and a loud banging sound?  2025 Events for Water Professionals Check out our Scaling UP! H2O Events Calendar where we've listed every event Water Treaters should be aware of by clicking HERE.  Â
In this episode host Marc Goldberg interviews Rogue Community College (RCC) and Southern Oregon University (SOU) graduate Jahna Thompson, Rogue Community College president, Dr. Randy Weber and Director, Postsecondary Success at The Ford Family Foundation, Denise Callahan. Jahna emphasizes the value of strong faculty mentorship and advising from her student experience at both Rogue Community College and SOU with a unique lens of having taught in her field of study at both institutions as a faculty/professor over the past year. She elaborates on her academic journey that began taking GED prep classes at RCC and after completing her Bachelor's and Master's degrees, she is currently pursuing a PhD in Immunology & Infectious Disease at Washington State University.President Weber reflects on Jahna's interview and describes specific college efforts through responsive programming, student supports and community partnerships that have helped increase enrollment and improve retention and completion outcomes for students, including those who enter the college taking adult education courses. Denise highlights the Foundation's impactful postsecondary education work across Oregon, particularly in rural communities, through Foundation investments, scholarships and research. She describes how the Foundation's work supporting over 1000 postsecondary education students annually across Oregon through scholarships helps inform the organization's policy and research work and shares more on the recently released Oregon by the Numbers report by the Foundation that offers a detailed profile for each of Oregon's 36 counties. The All In: Student Pathways Forward podcast is a part of Oregon's participation in the National Skills Coalition SkillSPAN network.
In episode 55 of Going anti-Viral, Dr Darcy Wooten joins host Dr Michael Saag to discuss navigating HIV care with glucagon-like peptide-1 (GLP-1) receptor agonists. Dr Wooten is a Professor of Medicine in the Division of Infectious Diseases at Washington University in St. Louis. Her clinical interests are HIV primary care, HIV prevention, sexually transmitted infections, and general infectious diseases. Dr Wooten is also a national leader in medical education. Dr Wooten provides an overview of GLP-1 receptor agonists including their history of use for the treatment of diabetes and more recent use for treatment of weight loss. Dr Saag and Dr Wooten discuss the challenges that patients have in getting insurance coverage for GLP-1 receptor agonists and review the 2 most common drugs that are used as treatment, tirzepatide and semaglutide. They discuss the patient experience with the injectable medication and review the possibility of oral versions of the medications in the future. Finally, Dr Saag and Dr Wooten discuss the long-term management of GLP-1 receptor agonists as a part of overall primary care for patients with HIV.0:00 – Introduction1:11 – Overview of GLP-1 receptor agonists3:46 – How GLP-1 receptor agonists became used for weight management and patient eligibility criteria6:14 – Challenges of insurance coverage for GLP-1 receptor agonists8:32 – Differences between theGLP-1 receptor agonists tirzepatide and semaglutide and other benefits of the medications beyond weight loss12:04 – Patient experience with the injectable formulations and possible adverse effects of use14:36 – Long-term use of GLP-1 receptor agonists and possibility of oral versions of these drugs17:36 – Managing GLP-1 receptor agonists as a part of primary care for patients with HIV including treatment of some substance use disorders20:22 – Predictions for future management of GLP-1 receptor agonists and Dr Wooten's hope for more research into incorporating lifestyle modifications into patient care __________________________________________________Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral's host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode.Follow Going anti-Viral on: Apple Podcasts YouTubeXFacebookInstagram...
This member-driven podcast is a benefit of membership of the Arizona Chapter of the American Academy of Pediatrics (AzAAP) and is intended for AzAAP pediatric healthcare members.AzAAP would like to acknowledge the generous support of the podcast by the Arizona Department of Health Services through the Title V Maternal and Child Health Services Block Grant funding. No information or content in this podcast is intended to substitute or replace a consultation with a healthcare provider or specialist. All non-healthcare providers should reach out to their child's pediatrician for guidance. Music: Wallpaper by Kevin MacLeodLink: https://incompetech.filmmusic.io/song/4604-wallpaperLicense: http://creativecommons.org/licenses/by/4.0/Â
In this episode of Let's Talk Micro, Dr. Jennifer Dien Bard and Dr. Lucas Osborn discuss their recent study on early growth antimicrobial susceptibility testing (AST). Traditional AST often requires 18–24 hours of incubation of isolates, delaying targeted treatment. Their research shows that using 6-hour early growth isolates with both automated and manual methods delivers accurate results up to 18 hours faster—without added costs or specialized equipment. The conversation explores the study design, agreement rates with standard methods, and what faster AST means for patient care and antimicrobial stewardship.  Link to study: https://doi.org/10.1128/jcm.00236-25 Link to disk diffusion study: https://doi.org/10.1128/jcm.03007-20  Check out the website: https://www.letstalkmicro.com/ Questions? Feedback? Send those to letstalkmicro@outlook.com Want to support the podcast? Here's how: Venmo: https://venmo.com/u/letstalkmicro Buy me a Ko-fi: https://ko-fi.com/letstalkmicro Â
On episode #87 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 7/31/25 – 8/18/25. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Adjuvanted recombinant zoster vaccine is effective against herpes zoster ophthalmicus, and is associated with lower risk of acute myocardial infarction and stroke in adults aged ≥50 years (CID) Bacterial Dalbavancin for Treatment of Staphylococcus aureus Bacteremia (JAMA) Propensity-Matched Comparison of Timely vs. Delayed Antibiotic Therapy in Stenotrophomonas maltophilia Pneumoni (OFID) The proportion of Treponema pallidum PCR-positive primary syphilis infections which are seronegative for syphilis (OFID) Cefixime versus benzathine penicillin G for the treatment of early syphilis (Journal of Antimicrobial Chemotherapy) Dalbavancin for Treatment of Staphylococcus aureus Bacteremia (JAMA) Fungal The Last of US Season 2 (YouTube) Parasitic Increasing Length of the Babesia Season in New England in the Climate Change Era (OFID) Ivermectin to Control Malaria (NEJM) Miscellaneous ACIP Recommendations Summary (CDC: Influenza) Relative effectiveness of high-dose versus standard-dose influenza vaccine against hospitalizations and mortality according to frailty score (JID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
Tom Frieden is the president and chief executive officer of Resolve to Save Lives and former director of the Centers for Disease Control and Prevention. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. T.R. Frieden. Dismantling Public Health Infrastructure, Endangering American Lives. N Engl J Med 2025;393:625-627.
Welcome to a world where medicine meets politics: a space that brings together scientific research, government wrangling, public push-back and healthcare conspiracies…Dr Anthony Fauci was the Director of America's National Institute of Allergy and Infectious Diseases for nearly four decades, during which time he not only helped study, treat and prevent viruses such as HIV/AIDS and Covid-19; he also advised seven US Presidents, from Ronald Regan through to Joe Biden.Along the way, Tony Fauci's picked up a public profile and taken a fair amount of flack; not least because of his complicated relationship with President Donald Trump. But he's also made great strides in medical research and policy, from working with activists who initially challenged him on the government response to HIV/AIDS - to spearheading the USA's PEPFAR project to share vital medication with developing nations.In a candid conversation with Professor Jim Al-Khalili, Tony discusses his childhood in Brooklyn, the dark early days of the HIV/AIDS epidemic and lessons from the Covid-19.Presented by Jim Al-Khalili Produced for BBC Studios by Lucy Taylor Reversion for World Service by Minnie Harrop