Podcasts about infectious

In the inaugural episode of Editors in Conversation mBio edition, Marvin Whiteley speaks with Arturo Casadevall, infectious-disease physician-scientist, founding Editor in Chief of mBio, and a leading voice in fungal pathogenesis and scientific rigor. They explore how climate change may be reshaping the fungal kingdom, potentially eroding the thermal barrier that has historically protected humans from most fungal pathogens. Using Candida auris (C auris) as a case study, they discuss heat adaptation, antifungal resistance, and what climate change could mean for future outbreaks. The conversation also examines fungal pandemics in pop culture, the challenges of antifungal drug development, and the promise of vaccines and biotechnology. Fungi are both threat and ally in a changing world, and understanding them has never been more urgent. Guest: Arturo Casadevall, M.D., Ph.D. - Johns Hopkins Bloomberg Distinguished Professor, Infectious-disease physician-scientist, Founding Editor in Chief of mBio® Links:  On the Emergence of Candida auris: Climate Change, Azoles, Swamps, and Birds  Reflections on my 15 years as mBio editor in chief This episode of Editors in Conversation is brought to you by mBio® and hosted by mBio Editor in Chief, Marvin Whiteley, Ph.D.  Visit journals.asm.org/journal/mbio to read articles and/or submit a manuscript. Receive up to 50% off fees when you publish in mBio® or any of the ASM journals by becoming an ASM member. Sign up at asm.org/joinasm.

In this episode, Dr. Mohammad Soleimani, MD, FICO, joins us to explore how artificial intelligence is transforming the diagnosis and management of infectious keratitis, a leading cause of preventable corneal blindness worldwide. We discuss challenges in differentiating bacterial from fungal infections, real-world AI performance, smartphone-based diagnostics for underserved regions, and persistent global equity gaps. Dr. Soleimani shares insights from his pioneering work at the intersection of technological innovation, global health, and ocular surface disease.

When Insurance Gets Between Doctors and PatientsDr. Elizabeth Ames and Dr. Caleb Bupp are deeply committed to their patients. But like so many clinicians today, they're spending an extraordinary amount of time battling insurance companies instead of practicing medicine.Between prior authorizations, step therapy requirements, and outright coverage denials, physicians and their teams are buried in paperwork, often at the direct expense of patient care. Time that should be spent listening, diagnosing, and treating is instead consumed by forms, phone calls, and appeals.Boston Globe reporter Jonathan Saltzman raised the concern and Dr. Ames brought it to my attention. The reporter talks about, a new program rolled out by Blue Cross Blue Shield of Massachusetts. The insurer says the initiative is designed to control rising healthcare costs for its 3 million members, noting that costs have increased by 30 percent since 2021. But, the program specifically targets physicians who bill for the most expensive visits. The reason for the increased expense, which is discussed in our podcast, is because doctors are choosing to spend more time with rare disease patients who have complicated health issues. They need to spend more time with complex medical needs patients than say, someone with a sore throat.Drs. Ames and Bupp warn that this approach fundamentally misunderstands patient care, particularly for those with complex or rare conditions. “These patients don't need less time; they need more” says Dr. Ames. Physicians argue that policies like this risk rushed appointments, strained doctor/patient relationships, and poorer outcomes. Nowhere is this more concerning than in the rare disease community, where delays and denials can be devastating.Dr. Elizabeth Ames and Dr. Caleb Bupp talk about what this looks like in real life. As pediatric geneticists, they see firsthand how insurance barriers impact families already navigating diagnostic odysseys, uncertainty, and fear. Their work sits at the intersection of cutting-edge science and deeply human stories, and insurance interference often disrupts both. Dr. Ames, “Usually we get faxes saying, this has been denied and we start working on it. But the family gets a letter that the drug they need, the process is delayed by a “no”. We try and have good communication and say, “hey, we got this denial,” we're working on it. But I think it's deaths by a thousand cuts for the family. Families take the denial as, “I'm not worth of coverage, and that's really hard”. Dr. Bupp says they have had to hire genetic counselors, a job that didn't exist even 5 years ago, “We have a job description in our organization for it now because of the complexities that come with trying to unravel these insurance situations”.We should also note that Dr. Ames, Dr. Bupp, and I all serve on the Rare Disease Advisory Council (RDAC) in Michigan. “I think rare disease advocacy, there is power in numbers. One person can be a huge difference maker, but it's not one plus one equals two. It really exponentially grows, and I think with things like rare disease advisory councils, that gives you a better connection within your state, for state government and for advocacy. And I also think, or I hope, that it gives a place for an individual to plug in and that can then magnify and amplify. their voice so that they're not alone”. Many states have RDAC's, You can see if your state has an RDAC. For more on the Michigan RDACIn this article and in the podcast we are not speaking on behalf of the council, but it's important to understand why bodies like RDAC exist in the first place. Michigan is home to approximately one million people living with rare diseases, and the RDAC was created to ensure their voices, and experiences help shape policy. RDAC meetings are open to the public, and anyone in Michigan can participate and offer public comment. We hope you join our meetings via zoom (sometimes hybrid).This conversation isn't just about insurance policies. It's about time, trust, and whether our healthcare system truly serves patients, especially those with the most complex needs. Speak up, share your story. Advocate. Make a difference, Mold the future, for future generations.To look at the Everylife Diagnosis Odyssey https://everylifefoundation.org/delayed-diagnosis-study/ discussed in the podcast.  Everylife impact of diagnosis: https://everylifefoundation.org/burden-study/ Please like, subscribe, and comment on our podcasts!Please consider making a donation: https://thebonnellfoundation.org/donate/The Bonnell Foundation website:https://thebonnellfoundation.orgEmail us at: thebonnellfoundation@gmail.com Watch our podcasts on YouTube: https://www.youtube.com/@laurabonnell1136/featuredThanks to our sponsors:Vertex: https://www.vrtx.comViatris: https://www.viatris.com/enRead us on Substack: https://substack.com/@lstb?utm_campaign=profile&utm_medium=profile-pageWatch our trailer of Embracing Egypt: https://youtu.be/RYjlB25Cr9Y

Frederico Amorim convida Ayrton Silveira e Flávio Barbieri para falar sobre diagnóstico de arboviroses em 4 partes:- Quando suspeitar?- Diferenças entre as arboviroses (dengue, chikungunya e zika)- Quais exames pedir?- Abordagem geralReferências:1. Pan American Health Organization. Recommendations for Laboratory Detection and Diagnosis of Arbovirus Infections in the Region of the Americas. Washington, D.C.: PAHO; 2023. Available from: https://doi.org/10.37774/9789275125878.2. WHO guidelines for clinical management of arboviral diseases: dengue, chikungunya, Zika and yellow fever. Geneva: World Health Organization; 2025. Licence: CC BY-NC-SA 3.0 IGO.3. Rosenberger, Kerstin D et al. “Early diagnostic indicators of dengue versus other febrile illnesses in Asia and Latin America (IDAMS study): a multicentre, prospective, observational study.” The Lancet. Global health vol. 11,3 (2023): e361-e372. doi:10.1016/S2214-109X(22)00514-94. https://www.gov.br/saude/pt-br/assuntos/saude-de-a-a-z/a/aedes-aegypti/monitoramento-das-arboviroses5. Dengue : diagnóstico e manejo clínico : adulto e criança [recurso eletrônico] / Ministério da Saúde, Secretaria de Vigilância em Saúde e Ambiente, Departamento de Doenças Transmissíveis. 6. ed. – Brasília : Ministério da Saúde, 2024.6. Shahsavand Davoudi, Amirhossein et al. “Ultrasound evaluation of gallbladder wall thickness for predicting severe dengue: a systematic review and meta-analysis.” The ultrasound journal vol. 17,1 12. 3 Feb. 2025, doi:10.1186/s13089-025-00417-57. Shabil, Muhammed et al. “Hypoalbuminemia as a predictor of severe dengue: a systematic review and meta-analysis.” Expert review of anti-infective therapy vol. 23,1 (2025): 105-118. doi:10.1080/14787210.2024.24487218. Tsheten, Tsheten et al. “Clinical predictors of severe dengue: a systematic review and meta-analysis.” Infectious diseases of poverty vol. 10,1 123. 9 Oct. 2021, doi:10.1186/s40249-021-00908-29. Boletim Epidemiológico – Monitoramento das arboviroses e balanço de encerramento do COE Dengue e outras Arboviroses 2024,Ministério da Saúde, Secretaria de Vigilância em Saúde e Ambiente, Volume 55, nº 11, 4 jul. 202410. Daumas, Regina P et al. “Clinical and laboratory features that discriminate dengue from other febrile illnesses: a diagnostic accuracy study in Rio de Janeiro, Brazil.” BMC infectious diseases vol. 13 77. 8 Feb. 2013, doi:10.1186/1471-2334-13-7711. Kamble N, Kumar VS, Rangaswamy DR, Kavatagi K. When it itches, dengue switches off: a retrospective case series. Bull Natl Res Cent. 2024;48:68. doi:10.1186/s42269-024-01225-y

Read "ME/CFS and Long COVID share similar symptoms and biological abnormalities: road map to the literature" – co-authored by Dr. Anthony L. Komaroff & W. Ian Lipkin. https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2023.1187163/full    Fatigue is the body's hard-wired response to a viral infection. In today's episode, Haylie Pomroy shares insights with Dr. Anthony L. Komaroff to examine the history of ME/CFS research, the causes and triggers of ME/CFS and other post-infectious chronic illnesses, and the abnormalities observed in the brain and autonomic nervous system among patients with ME/CFS and long COVID. Dr. Komaroff also addresses how patients have often been dismissed within the healthcare system, explains the physical and psychological processes involved in these conditions, and discusses how he and other clinicians are now moving to the forefront of diagnosis and treatment.   Register for the Integrative Medicine Luncheon featuring Dr. Payam Hakimi on  February 14, 2026. https://nova.zoom.us/meeting/register/RQnykYIKRZO-yVykmDp-YQ#/registration   Dr. Anthony L. Komaroff is a distinguished Professor of Medicine at Harvard Medical School and a Senior Physician at Brigham and Women's Hospital. He has held significant leadership roles, including Director of the Division of General Medicine and Primary Care at Brigham and Women's Hospital. Dr. Komaroff is known for his research on myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and human herpesvirus infections. He has published over 270 research articles and book chapters and served on numerous advisory committees for major health organizations.   LinkedIn: https://www.linkedin.com/in/anthony-l-komaroff-64133346/  Facebook: https://web.facebook.com/anthonyl.komaroff    Solve ME: https://solvecfs.org  Open Medicine Foundation: https://www.omf.ngo  National Institutes of Health (NIH): https://www.nih.gov/mecfs/about-mecfs  Centers for Disease Control and Prevention (CDC): https://www.cdc.gov/me-cfs/about/index.html   Haylie Pomroy, Founder and CEO of The Haylie Pomroy Group, is a leading health strategist specializing in metabolism, weight loss, and integrative wellness. With over 25 years of experience, she has worked with top medical institutions and high-profile clients, developing targeted programs and supplements rooted in the "Food is Medicine" philosophy. Inspired by her own autoimmune journey, she combines expertise in nutrition, biochemistry, and patient advocacy to help others reclaim their health. She is a New York Times bestselling author of The Fast Metabolism Diet.   Learn more about Haylie Pomroy's approach to wellness through her website: https://hayliepomroy.com   Instagram: https://www.instagram.com/hayliepomroy  Facebook: https://www.facebook.com/hayliepomroy  YouTube: https://www.youtube.com/@hayliepomroy/videos  LinkedIn: https://www.linkedin.com/in/hayliepomroy/  X: https://x.com/hayliepomroy    Enjoy our show? Please leave us a 5-star review so we can bring hope and help to others. You can also watch the show on our YouTube.https://www.youtube.com/@NSU_INIM   Sign up today for our newsletter. https://nova.us4.list-manage.com/subscribe?u=419072c88a85f355f15ab1257&id=5e03a4de7d    This podcast is brought to you by the Institute for Neuro-Immune Medicine. Learn more about us here.   Website: https://www.nova.edu/nim/ Facebook: https://www.facebook.com/InstituteForNeuroImmuneMedicine Instagram: https://www.instagram.com/NSU_INIM/ Twitter: https://www.twitter.com/NSU_INIM

It is widely accepted that over time, humanity will need to expand its presence into the solar system. What are the challenges? Well, space and our nearby worlds have proved to be a much greater challenge than we had long thought. While the rigors of zero-g have been well researched on the International Space Station, the challenges of living in lower gravity, such as that found on the moon and Mars, has not yet been explored. And human reproduction in space, along with genetic challenges, is a complete unknown. Rice Univeristy professor and researcher Scott Solomon joins us to explore these topics in depth, and to posit possible solutions. Headlines: Artemis 2 Moon Launch Faces More Delays Due to Hydrogen Leaks Perseverance Rover on Mars Completes First Fully AI-Driven Journey Study Warns of Urgent Need to Research Human Reproduction in Space Main Topic: Becoming Martian – What It Would Take for Humans to Thrive on Mars Biological impacts of space and Martian environments on the human body Gaps in research about reproduction, growth, and development in space and partial gravity Ethical, social, and medical challenges of having children beyond Earth The complexities of transplanting Earth's ecosystems, microbiomes, and the risk of disruptive species Evolutionary changes and the likely divergence of human populations living long-term off-Earth Considerations around modifying humans versus modifying extraterrestrial environments Infectious disease threats and dwindling biological immunity for space settlers Psychological, cultural, and population dynamics for future interplanetary communities Hosts: Rod Pyle and Tariq Malik Guest: Dr. Scott Solomon Download or subscribe to This Week in Space at https://twit.tv/shows/this-week-in-space. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit Sponsor: helixsleep.com/space

It is widely accepted that over time, humanity will need to expand its presence into the solar system. What are the challenges? Well, space and our nearby worlds have proved to be a much greater challenge than we had long thought. While the rigors of zero-g have been well researched on the International Space Station, the challenges of living in lower gravity, such as that found on the moon and Mars, has not yet been explored. And human reproduction in space, along with genetic challenges, is a complete unknown. Rice Univeristy professor and researcher Scott Solomon joins us to explore these topics in depth, and to posit possible solutions. Headlines: Artemis 2 Moon Launch Faces More Delays Due to Hydrogen Leaks Perseverance Rover on Mars Completes First Fully AI-Driven Journey Study Warns of Urgent Need to Research Human Reproduction in Space Main Topic: Becoming Martian – What It Would Take for Humans to Thrive on Mars Biological impacts of space and Martian environments on the human body Gaps in research about reproduction, growth, and development in space and partial gravity Ethical, social, and medical challenges of having children beyond Earth The complexities of transplanting Earth's ecosystems, microbiomes, and the risk of disruptive species Evolutionary changes and the likely divergence of human populations living long-term off-Earth Considerations around modifying humans versus modifying extraterrestrial environments Infectious disease threats and dwindling biological immunity for space settlers Psychological, cultural, and population dynamics for future interplanetary communities Hosts: Rod Pyle and Tariq Malik Guest: Dr. Scott Solomon Download or subscribe to This Week in Space at https://twit.tv/shows/this-week-in-space. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit Sponsor: helixsleep.com/space

It is widely accepted that over time, humanity will need to expand its presence into the solar system. What are the challenges? Well, space and our nearby worlds have proved to be a much greater challenge than we had long thought. While the rigors of zero-g have been well researched on the International Space Station, the challenges of living in lower gravity, such as that found on the moon and Mars, has not yet been explored. And human reproduction in space, along with genetic challenges, is a complete unknown. Rice Univeristy professor and researcher Scott Solomon joins us to explore these topics in depth, and to posit possible solutions. Headlines: Artemis 2 Moon Launch Faces More Delays Due to Hydrogen Leaks Perseverance Rover on Mars Completes First Fully AI-Driven Journey Study Warns of Urgent Need to Research Human Reproduction in Space Main Topic: Becoming Martian – What It Would Take for Humans to Thrive on Mars Biological impacts of space and Martian environments on the human body Gaps in research about human reproduction, growth, and development in space and partial gravity Ethical, social, and medical challenges of having children beyond Earth The complexities of transplanting Earth's ecosystems, microbiomes, and the risk of disruptive species Evolutionary changes and the likely divergence of human populations living long-term off-Earth Considerations around modifying humans versus modifying extraterrestrial environments Infectious disease threats and dwindling biological immunity for space settlers Psychological, cultural, and population dynamics for future interplanetary communities Hosts: Rod Pyle and Tariq Malik Guest: Dr. Scott Solomon Download or subscribe to This Week in Space at https://twit.tv/shows/this-week-in-space. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit Sponsor: helixsleep.com/space

It is widely accepted that over time, humanity will need to expand its presence into the solar system. What are the challenges? Well, space and our nearby worlds have proved to be a much greater challenge than we had long thought. While the rigors of zero-g have been well researched on the International Space Station, the challenges of living in lower gravity, such as that found on the moon and Mars, has not yet been explored. And human reproduction in space, along with genetic challenges, is a complete unknown. Rice Univeristy professor and researcher Scott Solomon joins us to explore these topics in depth, and to posit possible solutions. Headlines: Artemis 2 Moon Launch Faces More Delays Due to Hydrogen Leaks Perseverance Rover on Mars Completes First Fully AI-Driven Journey Study Warns of Urgent Need to Research Human Reproduction in Space Main Topic: Becoming Martian – What It Would Take for Humans to Thrive on Mars Biological impacts of space and Martian environments on the human body Gaps in research about reproduction, growth, and development in space and partial gravity Ethical, social, and medical challenges of having children beyond Earth The complexities of transplanting Earth's ecosystems, microbiomes, and the risk of disruptive species Evolutionary changes and the likely divergence of human populations living long-term off-Earth Considerations around modifying humans versus modifying extraterrestrial environments Infectious disease threats and dwindling biological immunity for space settlers Psychological, cultural, and population dynamics for future interplanetary communities Hosts: Rod Pyle and Tariq Malik Guest: Dr. Scott Solomon Download or subscribe to This Week in Space at https://twit.tv/shows/this-week-in-space. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit Sponsor: helixsleep.com/space

CardioNerds (Dr. Shazli Khan, Dr. Jenna Skowronski, and Dr. Shiva Patlolla) discuss the management of patients post‑heart transplantation with Dr. Shelley Hall from Baylor University Medical Center and Dr. MaryJane Farr from UTSW. In this comprehensive review, we cover the physiology of the transplanted heart, immunosuppression strategies, rejection surveillance, and long-term complications including cardiac allograft vasculopathy (CAV) and malignancy. Audio editing for this episode was performed by CardioNerds intern Dr. Bhavya Shah. Enjoy this Circulation 2022 Paths to Discovery article to learn about the CardioNerds story, mission, and values. CardioNerds Heart Success Series PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls The Denervated Heart: The donor heart is surgically severed from the autonomic nervous system, leading to a higher resting heart rate (90-110 bpm) due to loss of vagal tone. Because the heart relies on circulating catecholamines rather than neural input to increase heart rate, patients experience a delayed chronotropic response to exercise and stress. Importantly, because afferent pain fibers are severed, ischemia is often painless. Rejection Surveillance: Rejection is classified into Acute Cellular Rejection (ACR), which is T-cell mediated, and Antibody-Mediated Rejection (AMR), which is B-cell mediated. While endomyocardial biopsy remains the gold standard for diagnosis, non-invasive surveillance using gene-expression profiling (e.g., AlloMap) and donor-derived cell-free DNA (dd-cfDNA) is increasingly utilized to reduce the burden of invasive procedures. The Infection Timeline: The risk of infection follows a predictable timeline based on the intensity of immunosuppression. The first month is dominated by nosocomial infections. Months one through six are the peak for opportunistic infections (Cytomegalovirus, Pneumocystis, Toxoplasmosis) requiring prophylaxis. After six months, patients are primarily at risk for community-acquired pathogens, though late viral reactivation can occur. Cardiac Allograft Vasculopathy (CAV): Unlike native coronary artery disease, CAV presents as diffuse, concentric intimal thickening that affects the entire length of the vessel, including the microvasculature. Due to denervation, patients rarely present with angina; instead, CAV manifests as unexplained heart failure, fatigue, or sudden cardiac death. Malignancy Risk: Long-term immunosuppression significantly increases the risk of malignancy. Skin cancers (squamous and basal cell) are the most common, followed by Post-Transplant Lymphoproliferative Disorder (PTLD), which is often driven by Epstein-Barr Virus (EBV) reactivation. Notes Notes: Notes drafted by Dr. Patlolla 1. What are the unique physiological features of the transplanted heart? The hallmark of the transplanted heart is denervation. Because the autonomic nerve fibers are severed during harvest, the heart loses parasympathetic or vagal tone, resulting in a resting tachycardia (typically 90-110 bpm). The heart also loses the ability to mount a reflex tachycardia; thus, the heart rate response to exercise or hypovolemia relies on circulating catecholamines, which results in a slower “warm-up” and “cool-down” period during exertion. 2. What are the pillars of maintenance immunosuppression regimen? The triple drug maintenance regimen typically consists of: Calcineurin Inhibitor (CNI): Tacrolimus is preferred over cyclosporine. Key side effects include nephrotoxicity, hypertension, tremor, hyperkalemia, and hypomagnesemia. Antimetabolite: Mycophenolate mofetil (MMF) inhibits lymphocyte proliferation. Key side effects include leukopenia and GI distress. Corticosteroids: Prednisone is used for maintenance but is often weaned to low doses or discontinued after the first year to mitigate metabolic side effects (diabetes, osteoporosis, weight gain). 3. How is rejection classified and diagnosed? Rejection is the immune system’s response to the foreign graft and is categorized by the arm of the immune system involved: Acute Cellular Rejection (ACR): Mediated by T-lymphocytes infiltrating the myocardium. It is graded from 1R (mild) to 3R (severe) based on the extent of infiltration and myocyte damage. Antibody-Mediated Rejection (AMR): Mediated by B-cells producing donor-specific antibodies (DSAs) that attack the graft endothelium. It is diagnosed via histology (capillary swelling) and immunofluorescence (C4d staining). Diagnosis has historically relied on endomyocardial biopsy. However, non-invasive tools are gaining traction. Gene Expression Profiling (GEP) assesses the expression of genes associated with immune activation to rule out rejection in low-risk patients. Donor-Derived Cell-Free DNA (dd-cfDNA) measures the fraction of donor DNA in the recipient’s blood. Elevated levels suggest graft injury which can occur in both ACR and AMR. 4. What is the timeline of infectious risk and how does it guide prophylaxis? Infectious risk correlates with the net state of immunosuppression. < 1 Month (Nosocomial): Risks include surgical site infections, catheter-associated infections, and aspiration pneumonia. 1 – 6 Months (Opportunistic): This is the period of peak immunosuppression. Patients are at risk for PJP, CMV, Toxoplasma, and fungal infections. Prophylaxis typically includes Trimethoprim-Sulfamethoxazole (for PJP/Toxo) and Valganciclovir (for CMV, dependent on donor/recipient serostatus). > 6 Months (Community-Acquired): As immunosuppression is weaned, the risk profile shifts toward community-acquired respiratory viruses (Influenza, RSV) and pneumonias. However, patients with recurrent rejection requiring boosted immunosuppression remain at risk for opportunistic pathogens. 5. How does Cardiac Allograft Vasculopathy (CAV) differ from native CAD? CAV is the leading cause of late graft failure. Unlike the focal, eccentric plaques seen in native atherosclerosis, CAV is an immunologically driven process causing diffuse, concentric intimal hyperplasia. It affects both epicardial vessels and the microvasculature. Because of this diffuse nature, percutaneous coronary intervention (PCI) is often technically difficult and provides only temporary palliation. The only definitive treatment for severe CAV is re-transplantation. Surveillance is critical and is typically performed via annual coronary angiography, often using intravascular ultrasound (IVUS) to detect early intimal thickening before it is visible on the angiogram. References Costanzo MR, Dipchand A, Starling R, et al. The International Society of Heart and Lung Transplantation Guidelines for the care of heart transplant recipients. J Heart Lung Transplant. 2010;29(8):914-956. doi:10.1016/j.healun.2010.05.034. https://www.jhltonline.org/article/S1053-2498(10)00358-X/fulltext Kittleson MM, Kobashigawa JA. Cardiac Allograft Vasculopathy: Current Understanding and Treatment. JACC Heart Fail. 2017;5(12):857-868. doi:10.1016/j.jchf.2017.07.003. https://www.jacc.org/doi/10.1016/j.jchf.2017.07.003 Velleca A, Shullo MA, Dhital K, et al. The International Society for Heart and Lung Transplantation (ISHLT) guidelines for the care of heart transplant recipients. J Heart Lung Transplant. 2023;42(5):e1-e141. doi:10.1016/j.healun.2022.10.015. https://www.jhltonline.org/article/S1053-2498(22)02187-5/fulltext

Somewhere is the only release by Gum Country - a side project of the guitarist from artisanal grunge band The Courtneys. Infectious 1990s shoegaze rockery for the present day slacker - it's hard to believe an album this catchy can be so obscure. A 'blind listening' treasure to the fullest.

Dr. Matt Bernstein is a clinical psychiatrist and leading voice in metabolic psychiatry, with 25 years of experience helping people achieve lasting mental health and functional recovery. A Columbia graduate (summa cum laude) and Penn-trained physician, he completed residency at MGH/McLean, where he served as chief resident and later held senior leadership roles. Now Chief Medical Officer at Ellenhorn, he develops innovative, community-based models for mental health care and serves on advisory boards advancing the metabolic psychiatry movement. In this episode, Drs. Tro and Matthew talk about… (00:00) Intro (02:19) How Dr. Matthew found his way into metabolic psychiatry (05:53) Autoimmune encephalitis (09:59) Psychiatric health and the physical body (14:41) Infectious diseases causing psychiatric diseases (18:25) Psychiatric guidelines (23:04) How Dr. Matthew's clinic approaches the treatment of psychiatric disorders from a metabolic health perspective (26:31) How diet effects the brain (29:00) The most amazing case of disease reversal Dr. Matthew has seen recently (34:22) The data on the effectiveness of metabolic psychiatry and why many psychiatrists currently practicing are resistant to it (37:32) The great work being done to heal people at Accord Mental Health (43:27) Outro and plugs For more information, please see the links below. Thank you for listening! Links: Please consider supporting us on Patreon: https://www.lowcarbmd.com/ Resources Mentioned in this Episode: Dr. Matt Bernstein: Accord Mental Health: https://accordmh.com/ Ellenhorn: https://www.ellenhorn.com/ Dr. Brian Lenzkes:  Website: https://arizonametabolichealth.com/ Twitter: https://twitter.com/BrianLenzkes?ref_src=twsrc^google|twcamp^serp|twgr^author Dr. Tro Kalayjian:  Website: https://toward.health Twitter: https://twitter.com/DoctorTro IG: https://www.instagram.com/doctortro/ Toward Health App Join a growing community of individuals who are improving their metabolic health; together.  Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more.  Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888  Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US Learn more: https://toward.health/community/

2/01/2026The Healthy Matters PodcastS05_E08 - Where Are We with HIV in 2026?With Special Guests:  Dr. Amanda Noska, MD HIV in 2026 looks much different than it did when it first hit mainstream media in the early 1980s.  At the outset, there was an abundance of fear, very little understanding, and even less hope for those afflicted.  But over the last few decades, we've seen a series of major scientific breakthroughs that have changed our understanding and patient outcomes almost entirely.  But there's still plenty of work to do!On Episode 8, we'll have an in-depth conversation with infectious disease expert Dr. Amanda Noska (MD, MPH) to catch us up on the current state of both HIV and AIDS.  We'll cover the basics of these conditions, the progress that's been made, the current challenges we face, and what the road ahead looks like for our local and global communities.  This storyline is definitely one of hope and a great example of scientific progress in medicine.  We hope you'll join us!Got healthcare questions or ideas for future shows?Email - healthymatters@hcmed.orgCall - 612-873-TALK (8255)Get a preview of upcoming shows on social media and find out more about our show at www.healthymatters.org.

Agate Rubene is the artist and illustrator behind Restless & Infectious. Originally from Latvia, she is now based in Auckland, New Zealand.With a background in fashion and graphic design, Agate began her creative journey through fashion illustration—a foundation that continues to shape her distinctive style. Her work focuses on people and their actions, capturing emotion and celebrating life's pleasures with a light-hearted tone.She uses bright colour palettes, fluid shapes, and vibrant characters to craft alternative realities inspired by daily experiences, mood, and the aesthetic of pop culture.Agate creates bold, expressive paintings, custom commissions, and commercial illustrations that bring stories to life. She has collaborated with brands such as Dipsea, The Beauty Book, and Urbanaut, and her work has found homes with collectors worldwide—reflecting its universal appeal.https://restlessinfectious.com/https://www.instagram.com/restless_infectious/https://www.facebook.com/RestlessInfectiousAbout your host:Kate Hursthouse is a practising artist and trainee Creative Arts Therapist with over a decade of creative and community experience. She combines her background in design, illustration, and arts education with a growing therapeutic practice centred on inclusion, emotional wellbeing, and creative expression. Guided by empathy and curiosity, Kate supports individuals and groups to explore identity, connection, and growth through the transformative process of art-making.She started this podcast to try and answer the question: how do we continue to be creative and produce creative work, while raising children? Her goal is to create a little corner of the internet where creative mothers share their stories and gain a feeling of community, understanding and inspiration.https://www.katehursthouse.com/https://www.instagram.com/katehursthouse/https://www.instagram.com/creativemotherpodcast/A huge thanks to Auckland Council Creative Communities Scheme for supporting this season of the podcast.

SCP 835 is a mass of coral-like polyps. Individual polyps are larger than any known coral species, and most have grown to more than one meter in diameter. Content Warnings: End of the world, Gun violence,  Foul language, Body horror, thalassophobia, Humans swallowed whole, Infectious diseases, Alcohol abuse PatronsIcecreamtruck56, Jed Linafelt, Jacob Watt, Tyke Arbon, DownWithTheThickness3425, Titian Vermin, Nikkyb5y, DatKat, Zazo, Sylas ONeil, Tristan Wentworth, Jacob Jordan, and Max Cast & Crew SCP Archives was created by Pacific S. Obadiah & Jon GrilzSCP-835  was written by by Dr Gears and DrClef,Exit Strategy was written by SpoonOfEvilScript by Kevin WhitlockNarrator - Nate DufortLt. Campbell - Erika SandersonPodcaster - Chris Harris-BeecheyPundit - Brandon P. JenkinsDoctor - Hannah SchoonerNewscaster - Kale BrownScientist - Madeline Moore Dialogue Editor - Sam StarkArt - Eduardo Valdés-HeviaMusic- Newt SchottelkotteTheme Song- Mattie Roi BergerSound Designer - Brad ColbroockShowrunner - Daisy McNamaraCreative Director - Pacific S. ObadiahExecutive Producer - Tom Owen Presented by Bloody FMwww.Bloody-Disgusting.comwww.SCParchives.com Patreon: https://www.patreon.com/scp_podStore: https://store.dftba.com/collections/scp-archivesInstagram: https://www.instagram.com/scp_pod/Bluesky: https://bsky.app/profile/scparchives.bsky.socialDiscord: https://discord.gg/tJEeNUzeZXTikTok: https://www.tiktok.com/@scppodYouTube: https://www.youtube.com/c/scparchives Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

The U.S. Centers for Disease Control and Prevention has updated its childhood vaccination schedule, cutting back the number of immunizations from 17 to 11. Infectious-diseases specialist Dr. Caroline Quach-Thanh says Canada's schedule hasn't changed, but she worries the U.S. move could create confusion and fuel vaccine hesitancy here.For transcripts of The Dose, please visit: lnk.to/dose-transcripts. Transcripts of each episode will be made available by the next workday. For more episodes of this podcast, click this link.

Chris Anderson was inspired by the growth of TED once they expanded from being simply a conference company to adding the concept of offering their talks free to the world over the internet.   He's now calling on us all to "reclaim the internet" and use it as a force for spreading less hate and division and more kindness and generosity.  His new book, Infectious Generosity, lays out clearly the reasons why generosity is good for the world — as well as for us as individuals — then details a plan by which this movement can spread virally.  Chris's views on these subjects are aligned perfectly with the work of The Optimism institute and he shares them with great enthusiasm in this uplifting and inspiring episode of Blue Sky.    Chapters:  00:00 Welcome Chris Anderson to Blue Sky  Bill Burke welcomes Chris Anderson, head of TED, to the Blue Sky Podcast. Chris discusses his new book, "Infectious Generosity," and his mission to use the internet as a force for good, combating online division.  02:14 TED's Impact and TEDx's Success  Chris shares how TED made its videos freely available online, which surprisingly enhanced the conference rather than hurting it. He explains the success of TEDx, a free licensing model that enabled 65,000 volunteers to create events globally, generating billions of views.  06:00 The Internet's Downfall and Human Nature  Chris discusses how the internet, especially social media, went astray, preying on our 'lizard brains' and promoting outrage.   11:47 Generosity and Happiness  Chris explains the deep connection between generosity and happiness, citing a Chinese proverb that highlights helping others as a path to lifelong joy. He emphasizes that while the internet can be negative, it also offers a powerful tool for spreading positive change.  15:57 Reclaiming the Internet: Tactics  Chris discusses tactics for reclaiming the internet, focusing on making 'good stuff' go viral by evoking authentic human emotion. He uses the example of 'The Kindness Pandemic' Facebook group and highlights the need for creativity and courage to break through online negativity.  21:09 Our Role in Shaping Social Media  Chris emphasizes that users are not helpless in shaping their social media experience, stressing the importance of conscious choices in who to follow and what content to engage with.   27:47 The Uniqueness of Our Time and Generosity Strategy  Chris highlights the unique historical moment that allows for widespread generosity due to frictionless digital sharing and its reputation-building power.   33:06 Embracing Imperfect Generosity and Gratitude Chris encourages letting go of the idea of 'perfect generosity,' urging celebration of all motivations behind giving, even those with mixed intentions.   39:25 Podcast Recommendation and Host Reflections  Bill Burke recommends 'Two Lives,' a character-driven narrative podcast about overcoming darkness, which has received several awards.  42:21 Neuroplasticity, Optimism, and AI for Good  Chris discusses neuroplasticity and how our narratives shape us, emphasizing that kindness, like a muscle, grows with exercise. He introduces the Infectious Generosity Guru (TIG), an AI tool designed to help individuals brainstorm ways to spread generosity online.  49:15 A Vision for a Better Future  Chris outlines his continued work with TED, focusing on the Audacious Project to collaboratively fund large-scale change initiatives. He emphasizes that optimism is a stance—a determined effort to find and illuminate pathways to a better future, urging collective action to reclaim the internet and inspire change. 

RaeAnn Tucker from the Henry and Stark County Health Departments and First Choice Healthcare Clinics joined Wake Up Tri-Counties to discuss the increasing respiratory infection rates, Cervical Cancer Awareness Month, winter travel safety, sick appointments, and vaccines. Health matters are front and center in Henry and Stark counties this January. Local health officials emphasize the importance of cervical cancer prevention, urging regular screenings and HPV vaccinations for women and adolescents. As the flu season ramps up, residents are also encouraged to get their flu and COVID-19 vaccinations, now available at First Choice Healthcare clinics in Kewanee and Toulon. As winter settles in, safety tips include using low-beam headlights, preparing emergency car kits, avoiding carbon monoxide, and preventing frostbite. Free health insurance enrollment assistance will be available at several local venues this month; details are available at henrystarkhealth.com.

Samantha Rux from OSF HealthCare joined Wake Up Tri-Counties to talk about the February 12, 2026, Blood Drive at OSF Saint Luke Medical Center in Kewanee and the rising respiratory infectious rates in Illinois.  January marks National Blood Donor Month, and Samantha Rucks with OSF Healthcare is encouraging Tri-Counties residents to roll up their sleeves and give blood. The next community blood drive at St. Luke Medical Center is scheduled for February 12th from 7 AM to 5 PM. Regular donors are urged to make appointments, but walk-ins are also welcome. There's a constant need for all blood types, especially O-negative, and local donations primarily serve area patients. Donors can save up to three lives with a single donation and are treated to snacks and small gifts for their generosity. Details can be found at osfsaintluke.org or bloodcenter.org. As respiratory illnesses rise, hospitals remind visitors about potential restrictions and masking policies. If you're feeling unwell, utilize virtual urgent care or call ahead for appointments to ensure the community stays safe and healthy.

Comedian and Filmmaker, Cameron Smith, joins Nicole Barlow and Ryan Pak to talk about the soundtrack to the 2007 Jake Kasdan film, Walk Hard: The Dewey Cox Story. While the film flopped at the box office, it has become a cult classic and star, John C. Reilly is planning to take the Dewey Cox songs on tour in 2007 to celebrate the 20th anniversary of the film. We Discuss: - How the Film Influenced Cameron In His Formative Years - The Great Songs and the Massively Talented Songwriters Behind Them - John C. Reilly's Love of Music - Our Favorite Scenes, Performances, and The Beatles For More Information About Cameron Smith: Website YouTube Instagram TikTok Twitter Learn more about your ad choices. Visit megaphone.fm/adchoices

Drew Bennett | God Running To Us

Episode 210: Heat Stroke BasicsWritten by Jacob Dunn, MS4, American University of the Caribbean. Edits and comments by Hector Arreaza, MD.You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice. Definition:Heat stroke represents the most severe form of heat-related illness, characterized by a core body temperature exceeding 40°C (104°F) accompanied by central nervous system (CNS) dysfunction. Arreaza: Key element is the body temperature and altered mental status. Jacob: This life-threatening condition arises from the body's failure to dissipate heat effectively, often in the context of excessive environmental heat load or strenuous physical activity. Arreaza: You mentioned, it is a spectrum. What is the difference between heat exhaustion and heat stroke? Jacob: Unlike milder heat illnesses such as heat exhaustion, heat stroke involves multisystem organ dysfunction driven by direct thermal injury, systemic inflammation, and cytokine release. You can think of it as the body's thermostat breaking under extreme stress — leading to rapid, cascading failures if not addressed immediately. Arreaza: Tell us what you found out about the pathophysiology of heat stroke?Jacob: Pathophysiology: Under normal conditions, the body keeps its core temperature tightly controlled through sweating, vasodilation of skin blood vessels, and behavioral responses like seeking shade or drinking water. But in extreme heat or prolonged exertion, those mechanisms get overwhelmed.Once core temperature rises above about 40°C (104°F), the hypothalamus—the brain's thermostat—can't keep up. The body shifts from controlled thermoregulation to uncontrolled, passive heating. Heat stroke isn't just someone getting too hot—it's a full-blown failure of the body's heat-regulating system. Arreaza: So, it's interesting. the cell functions get affected at this point, several dangerous processes start happening at the same time.Jacob: Yes: Cellular Heat InjuryHigh temperatures disrupt proteins, enzymes, and cell membranes. Mitochondria start to fail, ATP production drops, and cells become leaky. This leads to direct tissue injury in vital organs like the brain, liver, kidneys, and heart.Arreaza: Yikes. Cytokines play a big role in the pathophysiology of heat stroke too. Jacob: Systemic Inflammatory ResponseHeat damages the gut barrier, allowing endotoxins to enter the bloodstream. This triggers a massive cytokine release—similar to sepsis. The result is widespread inflammation, endothelial injury, and microvascular collapse.Arreaza: What other systems are affected?Coagulation AbnormalitiesEndothelial damage activates the clotting cascade. Patients may develop a DIC-like picture: microthrombi forming in some areas while clotting factors get consumed in others. This contributes to organ dysfunction and bleeding.Circulatory CollapseAs the body shunts blood to the skin for cooling, perfusion to vital organs drops. Combine that with dehydration from sweating and fluid loss, and you get hypotension, decreased cardiac output, and worsening ischemia.Arreaza: And one of the key features is neurologic dysfunction.Jacob: Neurologic DysfunctionThe brain is extremely sensitive to heat. Encephalopathy, confusion, seizures, and coma occur because neurons malfunction at high temperatures. This is why altered mental status is the hallmark of true heat stroke.Arreaza: Cell injury, inflammation, coagulopathy, circulatory collapse and neurologic dysfunction. Jacob: Ultimately, heat stroke is a multisystem catastrophic event—a combination of thermal injury, inflammatory storm, coagulopathy, and circulatory collapse. Without rapid cooling and aggressive supportive care, these processes spiral into irreversible organ failure.Background and Types:Arreaza: Heat stroke is part of a spectrum of heat-related disorders—it is a true medical emergency. Mortality rate reaches 30%, even with optimal treatment. This mortality correlates directly with the duration of core hyperthermia. I'm reminded of the first time I heard about heat stroke in a baby who was left inside a car in the summer 2005. Jacob: There are two primary types: -nonexertional (classic) heat stroke, which develops insidiously over days and predominantly affects vulnerable populations like children, the elderly, and those with chronic illnesses during heat waves; -exertional heat stroke, which strikes rapidly in young, otherwise healthy individuals, often during intense exercise in hot, humid conditions. Arreaza: In our community, farm workers are especially at risk of heat stroke, but any person living in the Central Valley is basically at risk.Jacob: Risk factors amplify vulnerability across both types, including dehydration, cardiovascular disease, medications that impair sweating (e.g., anticholinergics), and acclimatization deficits. Notably, anhidrosis (lack of sweating) is common but not required for diagnosis. Hot, dry skin can signal the shift from heat exhaustion to stroke. Arreaza: What other conditions look like heat stroke?Differential Diagnosis:Jacob: Presenting with altered mental status and hyperthermia, heat stroke demands a broad differential to avoid missing mimics. -Environmental: heat exhaustion, syncope, or cramps. -Infectious etiologies like sepsis or meningitis must be ruled out. -Endocrine emergencies such as thyroid storm, pheochromocytoma, or diabetic ketoacidosis (DKA) can overlap. -Neurologic insults include cerebrovascular accident (CVA), hypothalamic lesions (bleeding or infarct), or status epilepticus. -Toxicologic culprits are plentiful—sympathomimetic or anticholinergic toxidromes, salicylate poisoning, serotonin syndrome, malignant hyperthermia, neuroleptic malignant syndrome (NMS), or even alcohol/benzodiazepine withdrawal. When it comes to differentials, it is always best to cast a wide net and think about what we could be missing if this is not heat stroke. Arreaza: Let's say we have a patient with hyperthermia and we have to assess him in the ER. What should we do to diagnose it?Jacob: Workup:Diagnosis is primarily clinical, hinging on documented hyperthermia (>40°C) plus CNS changes (e.g., confusion, delirium, seizures, coma) in a hot environment. Arreaza: No single lab confirms it, but targeted testing allows us to detect complications and rule out alternative diagnosis. Jacob: -Start with ECG to assess for dysrhythmias or ischemic changes (sinus tachycardia is classic; ST depressions or T-wave inversions may hint at myocardial strain). -Labs include complete blood count (CBC), comprehensive metabolic panel (electrolytes, renal function, liver enzymes), glucose, arterial blood gas, lactate (elevated in shock), coagulation studies (for disseminated intravascular coagulation, or DIC), creatine kinase (CK) and myoglobin (for rhabdomyolysis), and urinalysis. Toxicology screen if history suggests. Arreaza: I can imagine doing all this while trying to cool down the patient. What about imaging?-Imaging: chest X-ray for pulmonary issues, non-contrast head CT if neurologic concerns suggest edema or bleed (consider lumbar puncture if infection suspected). It is important to note that continuous core temperature monitoring—via rectal, esophageal, or bladder probe—is essential, not just peripheral skin checks. Arreaza: TreatmentManagement:Time is tissue here—initiate cooling en route, if possible, as delays skyrocket morbidity. ABCs first: secure airway (intubate if needed, favoring rocuronium over succinylcholine to avoid hyperkalemia risk), support breathing, and stabilize circulation. -Remove the patient from the heat source, strip clothing, and launch aggressive cooling to target 38-39°C (102-102°F) before halting to prevent rebound hypothermia. -For exertional cases, ice-water immersion reigns supreme—it's the fastest method, with immersion in cold water resulting in near-100% survival if started within 30 minutes. -Nonexertional benefits from evaporative cooling: mist with tepid water (15-25°C) plus fans for convective airflow. -Adjuncts include ice packs to neck, axillae, and groin; -room-temperature IV fluids (avoid cold initially to prevent shivering); -refractory cases, invasive options like peritoneal lavage, endovascular cooling catheters, or even ECMO. -Fluid resuscitation with lactated Ringer's or normal saline (250-500 mL boluses) protects kidneys and counters rhabdomyolysis—aim for urine output of 2-3 mL/kg/hour. Arreaza: What about medications?Jacob: Benzodiazepines (e.g., lorazepam) control agitation, seizures, or shivering; propofol or fentanyl if intubated. Avoid antipyretics like acetaminophen. For intubation, etomidate or ketamine as induction agents. Hypotension often resolves with cooling and fluids; if not, use dopamine or dobutamine over norepinephrine to avoid vasoconstriction. Jacob: What IV fluid is recommended/best for patients with heat stroke?Both lactated Ringer's solution and normal saline are recommended as initial IV fluids for rehydration, but balanced crystalloids such as LR are increasingly favored due to their lower risk of hyperchloremic metabolic acidosis and AKI. However, direct evidence comparing the two specifically in the setting of heat stroke is limited. Arreaza: Are cold IV fluids better/preferred over room temperature fluids?Cold IV fluids are recommended as an adjunctive therapy to help lower core temperature in heat stroke, but they should not delay or replace primary cooling methods such as cold-water immersion. Cold IV fluids can decrease core temperature more rapidly than room temperature fluids. For example, 30mL/kg bolus of chilled isotonic fluids at 4 degrees Celsius over 30 minutes can decrease core temperature by about 1 degree Celsius, compared to 0.5 degree Celsius with room temperature fluids. Arreaza: Getting cold IV sounds uncomfortable but necessary for those patients. Our favorite topic.Screening and Prevention:-Heat stroke prevention focuses on public health and individual awareness rather than routine testing. -High-risk groups—elderly, children, athletes, laborers, or those on impairing meds—should acclimatize gradually (7-14 days), hydrate preemptively (electrolyte solutions over plain water), and monitor temperature in exertional settings. -Communities during heat waves need cooling centers and alerts. -For clinicians, educate patients with CVD or obesity about early signs like dizziness or nausea. -No formal "screening" exists, but vigilance in EDs during summer surges saves lives. -Arreaza: I think awareness is a key element in prevention, so education of the public through traditional media like TV, and even social media can contribute to the prevention of this catastrophic condition.Jacob: Ya so heat stroke is something that should be on every physician's radar in the central valley especially in the summer time given the hot temperatures. Rapid recognition is key. Arreaza: Thanks, Jacob for this topic, and until next time, this is Dr. Arreaza, signing off.Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! References:Gaudio FG, Grissom CK. Cooling Methods in Heat Stroke. J Emerg Med. 2016 Apr;50(4):607-16. doi: 10.1016/j.jemermed.2015.09.014. Epub 2015 Oct 31. PMID: 26525947. https://pubmed.ncbi.nlm.nih.gov/26525947/.Platt, M. A., & LoVecchio, F. (n.d.). Nonexertional classic heat stroke in adults. In UpToDate. Retrieved September 7, 2025, from https://www.uptodate.com/contents/nonexertional-classic-heat-stroke-in-adults. (Key addition: Emphasizes insidious onset in at-risk populations and the role of urban heat islands in exacerbating classic cases.) Heat Stroke. WikEM. Retrieved December 3, 2025, from https://wikem.org/wiki/Heat_stroke. (Key additions: Details on cooling rates for immersion therapy, confirmation that anhidrosis is not diagnostic, and fluid titration to urine output for rhabdomyolysis prevention.)Theme song, Works All The Time by Dominik Schwarzer, YouTube ID: CUBDNERZU8HXUHBS, purchased from https://www.premiumbeat.com/. 

From announcing then backtracking on a cause for autism to slashing federal public health funding to changing childhood vaccine recommendations, the appointment of Robert F. Kennedy Jr. as the Secretary of the Department of Health and Human Services triggered an earthquake of change in U.S. public health policy. Infectious diseases doctor Peter Hotez, MD, PhD, assesses the still rattling landscape with TPR's Bonnie Petrie.

Episode 93 | Injection of Inspiration (2) Infectious Enthusiasm

Osteomyelitis in children is common enough to miss and serious enough to matter. In this episode of PEM Currents, we review a practical, evidence-based approach to pediatric acute hematogenous osteomyelitis, focusing on diagnostic strategy, imaging decisions including FAST MRI, and modern antibiotic management. Topics include age-based microbiology, empiric and pathogen-directed antibiotic selection with dosing, criteria for early transition to oral therapy, and indications for orthopedic and infectious diseases consultation. Special considerations such as MRSA, Kingella kingae, daycare clustering, and shortened treatment durations are discussed with an emphasis on safe, high-value care. Learning Objectives After listening to this episode, learners will be able to: Identify the key clinical, laboratory, and imaging findings that support the diagnosis of acute hematogenous osteomyelitis in children, including indications for FAST MRI and contrast-enhanced MRI. Select and dose appropriate empiric and pathogen-directed antibiotic regimens for pediatric osteomyelitis based on patient age, illness severity, and local MRSA prevalence, and determine when early transition to oral therapy is appropriate. Determine when consultation with orthopedics and infectious diseases is indicated, and recognize clinical features that warrant prolonged therapy or more conservative management. References Woods CR, Bradley JS, Chatterjee A, et al. Clinical practice guideline by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America: 2021 guideline on diagnosis and management of acute hematogenous osteomyelitis in pediatrics. J Pediatric Infect Dis Soc. 2021;10(8):801-844. doi:10.1093/jpids/piab027 Woods CR, Bradley JS, Chatterjee A, et al. Clinical practice guideline by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America: 2023 guideline on diagnosis and management of acute bacterial arthritis in pediatrics. J Pediatric Infect Dis Soc. 2024;13(1):1-59. doi:10.1093/jpids/piad089 Stephan AM, Platt S, Levine DA, et al. A novel risk score to guide the evaluation of acute hematogenous osteomyelitis in children. Pediatrics. 2024;153(1):e2023063153. doi:10.1542/peds.2023-063153 Alhinai Z, Elahi M, Park S, et al. Prediction of adverse outcomes in pediatric acute hematogenous osteomyelitis. Clin Infect Dis. 2020;71(9):e454-e464. doi:10.1093/cid/ciaa211 Burns JD, Upasani VV, Bastrom TP, et al. Age and C-reactive protein associated with improved tissue pathogen identification in children with blood culture-negative osteomyelitis: results from the CORTICES multicenter database. J Pediatr Orthop. 2023;43(8):e603-e607. doi:10.1097/BPO.0000000000002448 Peltola H, Pääkkönen M. Acute osteomyelitis in children. N Engl J Med. 2014;370(4):352-360. doi:10.1056/NEJMra1213956 Transcript This transcript was provided via use of the Descript AI application Welcome to PEM Currents, the Pediatric Emergency Medicine Podcast. As always, I'm your host, Brad Sobolewski, and today we're covering osteomyelitis in children. We're going to talk about diagnosis and imaging, and then spend most of our time where practice variation still exists: antibiotic selection, dosing, duration, and the evidence supporting early transition to oral therapy. We'll also talk about when to involve orthopedics, infectious diseases, and whether daycare outbreaks of osteomyelitis are actually a thing. So what do I mean by pediatric osteomyelitis? In children, osteomyelitis is most commonly acute hematogenous osteomyelitis. That means bacteria seed the bone via the bloodstream. The metaphysis of long bones is particularly vulnerable due to vascular anatomy that favors bacterial deposition. Age matters. In neonates, transphyseal vessels allow infection to cross into joints, increasing the risk of concomitant septic arthritis. In older children, those vessels involute, and infection tends to remain metaphyseal and confined to bone rather than spreading into the joint. For children three months of age and older, empiric therapy must primarily cover Staphylococcus aureus, which remains the dominant pathogen. Other common organisms include group A streptococcus and Streptococcus pneumoniae. In children six to 36 months of age, especially those in daycare, Kingella kingae is an important and often underrecognized pathogen. Kingella infections are typically milder, may present with lower inflammatory markers, and frequently yield negative routine cultures. Kingella is usually susceptible to beta-lactams like cefazolin, but is consistently resistant to vancomycin and often resistant to clindamycin and antistaphylococcal penicillins. This has direct implications for empiric antibiotic selection. Common clinical features of osteomyelitis include fever, localized bone pain, refusal to bear weight, and pain with movement of an adjacent joint. Fever may be absent early, particularly with less virulent organisms like Kingella. A normal white blood cell count does not exclude osteomyelitis. Only about one-third of children present with leukocytosis. CRP and ESR are generally more useful, particularly CRP for monitoring response to therapy. No single CRP cutoff reliably diagnoses or excludes osteomyelitis in children. While CRP is elevated in most cases of acute hematogenous osteomyelitis, the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America note that high-quality data defining diagnostic thresholds are limited. A CRP above 20 milligrams per liter is commonly used to support clinical suspicion, with pooled sensitivity estimates around 80 to 85 percent, but no definitive value mandates the diagnosis. Lower values do not exclude disease, particularly in young children, as CRP is normal in up to 40 percent of Kingella kingae infections. CRP values tend to be higher in Staphylococcus aureus infections, especially MRSA, and higher levels are associated with complications such as abscess, bacteremia, and thrombosis, though specific cutoffs are not absolute. In summary, CRP is most useful for monitoring treatment response. It typically peaks two to four days after therapy initiation and declines rapidly with effective treatment, with a 50 percent reduction within four days seen in the majority of uncomplicated cases. Blood cultures should be obtained in all children with suspected osteomyelitis, ideally before starting antibiotics when feasible. In children, blood cultures alone can sometimes identify the pathogen. Plain radiographs are still recommended early, not because they're sensitive for acute osteomyelitis, but because they help exclude fracture, malignancy, or foreign body and establish a baseline. MRI with and without contrast is the preferred advanced imaging modality. MRI confirms the diagnosis, defines the extent of disease, and identifies complications such as subperiosteal abscess, physeal involvement, and concomitant septic arthritis. MRI findings can also guide the need for surgical consultation. Many pediatric centers now use FAST MRI protocols for suspected osteomyelitis, particularly from the emergency department. FAST MRI uses a limited sequence set, typically fluid-sensitive sequences like STIR or T2 with fat suppression, without contrast. These studies significantly reduce scan time, often avoid the need for sedation, and retain high sensitivity for bone marrow edema and soft tissue inflammation. FAST MRI is particularly useful when the clinical question is binary: is there osteomyelitis or not? It's most appropriate in stable children without high concern for abscess, multifocal disease, or surgical complications. If FAST MRI is positive, a full contrast-enhanced MRI may still be needed to delineate abscesses, growth plate involvement, or adjacent septic arthritis. If FAST MRI is negative but clinical suspicion remains high, further imaging may still be necessary. The Pediatric Infectious Diseases Society and the Infectious Diseases Society of America recommend empiric antibiotic selection based on regional MRSA prevalence, patient age, and illness severity, with definitive therapy guided by culture results and susceptibilities. Empiric therapy should never be delayed in an ill-appearing or septic child. In well-appearing, stable children, antibiotics may be briefly delayed to obtain imaging or tissue sampling, but this requires close inpatient observation. For children three months and older with non–life-threatening disease, empiric therapy hinges on local MRSA rates. In regions with low community-acquired MRSA prevalence, generally under 10 percent, reasonable empiric options include cefazolin, oxacillin, or nafcillin. When MRSA prevalence exceeds 10 to 20 percent, empiric therapy should include an MRSA-active agent. Clindamycin is appropriate when local resistance rates are low, while vancomycin is preferred when clindamycin resistance is common or the child has had significant healthcare exposure. For children with severe disease or sepsis, vancomycin is generally preferred regardless of local MRSA prevalence. Some experts recommend combining vancomycin with oxacillin or nafcillin to ensure optimal coverage for MSSA, group A streptococcus, and MRSA. In toxin-mediated or high-inoculum infections, the addition of clindamycin may be beneficial due to protein synthesis inhibition. Typical IV dosing includes cefazolin 100 to 150 milligrams per kilogram per day divided every eight hours; oxacillin or nafcillin 150 to 200 milligrams per kilogram per day divided every six hours; clindamycin 30 to 40 milligrams per kilogram per day divided every six to eight hours; and vancomycin 15 milligrams per kilogram every six hours for serious infections, with appropriate monitoring. Ceftaroline or daptomycin may be considered in select MRSA cases when first-line agents are unsuitable. For methicillin-susceptible Staphylococcus aureus, first-generation cephalosporins or antistaphylococcal penicillins remain the preferred parenteral agents. For oral therapy, high-dose cephalexin, 75 to 100 milligrams per kilogram per day divided every six hours, is preferred. Clindamycin is an alternative when beta-lactams cannot be used. For clindamycin-susceptible MRSA, clindamycin is the preferred IV and oral agent due to excellent bioavailability and bone penetration, and it avoids the renal toxicity associated with vancomycin. For clindamycin-resistant MRSA, vancomycin or ceftaroline are preferred IV agents. Oral options are limited, and linezolid is generally the preferred oral agent when transition is possible. Daptomycin may be used parenterally in children older than one year without pulmonary involvement, typically with infectious diseases and pharmacy input. Beta-lactams remain the drugs of choice for Kingella kingae, Streptococcus pyogenes, and Streptococcus pneumoniae. Vancomycin has no activity against Kingella, and clindamycin is often ineffective. For Salmonella osteomyelitis, typically seen in children with sickle cell disease, third-generation cephalosporins or fluoroquinolones are used. In underimmunized children under four years, consider Haemophilus influenzae type b, with therapy guided by beta-lactamase production. Doxycycline has not been prospectively studied in pediatric acute hematogenous osteomyelitis. There are theoretical concerns about reduced activity in infected bone and risks related to prolonged therapy. While short courses are safe for certain infections, the longer durations required for osteomyelitis increase the risk of adverse effects. Doxycycline should be considered only when no other active oral option is available, typically in older children, and with infectious diseases consultation. It is not appropriate for routine treatment. Many hospitals automatically consult orthopedics when children are admitted with osteomyelitis, and this is appropriate. Early orthopedic consultation should be viewed as team-based care, not failure of medical management. Consult orthopedics when MRI shows abscess or extensive disease, there is concern for septic arthritis, the child fails to improve within 48 to 72 hours, imaging suggests devitalized bone or growth plate involvement, there is a pathologic fracture, the patient is a neonate, or diagnostic bone sampling or operative drainage is being considered. Routine surgical debridement is not required for uncomplicated cases. Infectious diseases consultation is also often automatic and supported by guidelines. ID is particularly valuable for antibiotic selection, dosing, IV-to-oral transition, duration decisions, bacteremia management, adverse reactions, and salvage regimens. Even in straightforward cases, ID involvement often facilitates shorter IV courses and earlier oral transition. Osteomyelitis is generally not contagious, and clustering is uncommon for Staphylococcus aureus. Kingella kingae is the key exception. It colonizes the oropharynx of young children and spreads via close contact. Clusters of invasive Kingelladisease have been documented in daycare settings. Suspicion should be higher in children six to 36 months from the same daycare, with recent viral illness, mild systemic symptoms, refusal to bear weight, modest CRP elevation, and negative routine cultures unless PCR testing is used. Public health intervention is not typically required, but awareness is critical. There is no minimum required duration of IV therapy for uncomplicated acute hematogenous osteomyelitis. Transition to oral therapy should be based on clinical improvement plus CRP decline. Many children meet criteria within two to six days. Oral antibiotics must be dosed higher than standard outpatient regimens to ensure adequate bone penetration. Common regimens include high-dose cephalexin, clindamycin, or linezolid in select cases. The oral agent should mirror the IV agent that produced clinical improvement. Total duration is typically three to four weeks, and in many cases 15 to 20 days is sufficient. MRSA infections or complicated cases usually require four to six weeks. Early oral transition yields outcomes comparable to prolonged IV therapy with fewer complications. Most treatment-related complications occur during parenteral therapy, largely due to catheter-related issues. Take-home points: osteomyelitis in children is a clinical diagnosis supported by labs and MRI. Empiric antibiotics should be guided by age, illness severity, and local MRSA prevalence. Early transition to high-dose oral therapy is safe and effective when clinical response and CRP support it. Orthopedics and infectious diseases consultation improve care and reduce variation. FAST MRI is changing how we diagnose osteomyelitis. Daycare clustering is uncommon except with Kingella kingae. That's all for this episode. If there are other topics you'd like us to cover, let me know. If you have the time, leave a review on your favorite podcast platform. It helps more people find the show and learn from it. For PEM Currents, this has been Brad Sobolewski. See you next time.    

In this episode of ASTCT Talks, supported by an educational grant from Sanofi US, host Dr. Corey Cutler, MD, from Dana-Farber Cancer Institute, sits down with Dr. Sanjeet Singh Dadwal, MD, chief of infectious diseases at City of Hope, to explore a critical aspect of chronic graft-versus-host disease (GVHD): immune dysfunction and infection risk.The discussion highlights:• How chronic GVHD independently contributes to immune deficits and infection susceptibility.• Infectious risks associated with FDA-approved therapies for chronic GVHD.• Common infections in this population and why vigilance matters.• Practical guidance on prophylaxis strategies, vaccination timing, and navigating real-world challenges like food safety.This episode offers actionable insights for clinicians managing infection prevention and survivorship care in patients with chronic GVHD.Read “Infectious Disease Considerations in Chronic Graft-versus-Host Disease and Transplantation Survivors,” included in the 2024 GVHD Supplement collection published by Transplantation and Cellular Therapy.

Support the Institute today. https://givenow.nova.edu/the-institute-for-neuro-immune-medicine-inim-2025   In this episode, Haylie Pomroy is joined by Cort Johnson, Founder and Director of Health Rising, and Dr. Nancy Klimas, Director of the Institute for Neuro-Immune Medicine, for an in-depth discussion on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), post-infectious illness, and long COVID, and why countless patients continue to be misunderstood and misdiagnosed. They  trace the history of how ME/CFS has gained long-overdue recognition in the medical field, offering a deeper understanding of self-advocacy and discussing why practical, sensible support is essential to healing. They also highlight how Health Rising is expanding access to information and resources, how the Institute has been positioned at the forefront of long COVID research and clinical care, and the ongoing challenges of securing federal support and funding for patients and long-term research efforts.   Sign up for the COVID-UPP Study: https://redcap.nova.edu/redcap/surveys/?s=RMEDJ7LKCX&_gl=1*1h830h7*_gcl_au*MTM2NDA0MTQyOS4xNzE1MDA0ODAy   If you are interested in joining a Gulf War Illness (GWI) trial, please complete the Recruitment Registry Form. https://redcap.nova.edu/redcap/surveys/?s=Y9YF8JJWJRK8HEKL%20&_gl=1*1fipp18*_gcl_aw*R0NMLjE3MDc5MTgwMzIuRUFJYUlRb2JDaE1JeWNyUXVfcXFoQU1WU1pCYUJSM3AyQWRBRUFBWUFTQUFFZ0s1NWZEX0J3RQ..*_gcl_au*MTg2NjgwMDQ4Ni4xNzA3MTQwNzgx   Cort Johnson is the founder and director of Health Rising – a website dedicated to covering the latest research and treatment possibilities for chronic fatigue syndrome (ME/CFS) and fibromyalgia (FM). Cort came down with ME/CFS/FM while engaged in an Environmental Studies program at the University of California at Santa Cruz during the 1980's. Unable to complete the program at UCSC due to ME/CFS/FM, Cort received a BA in Philosophy from Cal State Long Beach in the late 1980′s, and then an MS in Environmental Studies from San Jose State University in 2000. In 2015, Cort was Prohealth's Advocate of the Year. In 2016, he received a Special Services award from the organization supporting ME/CFS professionals – the International Association of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (IACFS/ME). Health Rising has also been named one of the best fibromyalgia blogs.   Instagram: https://x.com/CortJohnson  Facebook: https://www.facebook.com/cort.johnson.9/  LinkedIn: https://www.linkedin.com/in/cort-johnson-53097213/ Twitter: https://x.com/CortJohnson   Learn more about Health Rising. Website: https://www.healthrising.org/    Dr. Nancy Klimas, a clinical immunologist by training, is the director of the Institute for Neuro-Immune Medicine, who has devoted her life to helping other people find cures for their complex illnesses that were once considered helpless. She works with her fellow medical experts in researching and analyzing the deeper causes of such diseases, particularly on the neuro-immunity side, to provide the best option suited for every single case or story they handle.   LinkedIn: https://www.linkedin.com/in/nancy-klimas-49255178/    Twitter: https://x.com/ngklimas?s=20    Instagram: https://instagram.com/nancyklimas   Haylie Pomroy, Founder and CEO of The Haylie Pomroy Group, is a leading health strategist specializing in metabolism, weight loss, and integrative wellness. With over 25 years of experience, she has worked with top medical institutions and high-profile clients, developing targeted programs and supplements rooted in the "Food is Medicine" philosophy. Inspired by her own autoimmune journey, she combines expertise in nutrition, biochemistry, and patient advocacy to help others reclaim their health. She is a New York Times bestselling author of The Fast Metabolism Diet.   Learn more about Haylie Pomroy's approach to wellness through her website: https://hayliepomroy.com   Instagram: https://www.instagram.com/hayliepomroy  Facebook: https://www.facebook.com/hayliepomroy  YouTube: https://www.youtube.com/@hayliepomroy/videos  LinkedIn: https://www.linkedin.com/in/hayliepomroy/  X: https://x.com/hayliepomroy    Enjoy our show? Please leave us a 5-star review on the following platforms so we can bring hope and help to others.   Apple Podcasts: https://podcasts.apple.com/us/podcast/hope-and-help-for-fatigue-chronic-illness/id1724900423   Spotify: https://open.spotify.com/show/154isuc02GnkPEPlWfdXMT   Sign up today for our newsletter. https://nova.us4.list-manage.com/subscribe?u=419072c88a85f355f15ab1257&id=5e03a4de7d   This podcast is brought to you by the Institute for Neuro-Immune Medicine. Learn more about us here.   Website: https://www.nova.edu/nim/ Facebook: https://www.facebook.com/InstituteForNeuroImmuneMedicine Instagram: https://www.instagram.com/NSU_INIM/ Twitter: https://www.twitter.com/NSU_INIM

Infectious diseases physician Jake Scott returns to TWiV to discuss the dangerous anti-vaccine policies being established in the US and what RFK Jr. and his associates get wrong. Hosts: Vincent Racaniello, Rich Condit, and Angela Mingarelli Guest: Jake Scott Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Vaccine RCT spreadsheet (CIDRAP) What RFK Jr gets wrong about vaccines (Conversation) RFK Jr's case against mRNA vaccines collapses (STAT) Too many kids' vaccines? Think again (STAT) Timestamps by Jolene Ramsey. Thanks! Weekly Picks Angela – Angela Palmer, science meets art (one, two) Rich – TWiV Special: A Shot of Hep B with Thomas Tu; TWiV Special: A shot of HepB with Chari Cohen Vincent – TSA is checking senior's phones for these 5 apps Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

Greg Brady welcomed Dr. Isaac Bogoch, Infectious disease specialist to the studio to discuss seventh patient ‘cured' of HIV: why scientists are excited. Learn more about your ad choices. Visit megaphone.fm/adchoices

TWiP solves the case about the man with abnormal brain MRI, and presents a new case for your solving about a man with some electrolyte issues related to his end-stage renal disease. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server TWiP study – information and survey Letters read on TWiP 270 New Case A man in his 20s is admitted to the hospital with some electrolyte issues related to his end-stage renal disease. Infectious disease is consulted as he has a report of a recent positive strongyloides serology test that was done as part of his pre-transplant evaluation. He reports no international travel, no interesting exposures. Become a patron of TWiP  Send your questions and comments to twip@microbe.tv Music by Ronald Jenkees Dear TWiP listeners, Have you ever wondered how TWiP shapes your understanding of science? We have! To find out more, Christina and the team are running a survey based study to learn more about how TWiP contributes to your scientific literacy and trust in science. Listen to the segment in this episode (TWiP 267) where Christina discusses the study's aims and scope.   Anyone who listens to TWiP can participate. The survey is anonymous and we do not collect personal data that could identify you. There are no potential disadvantages or harms in taking part, other than using a few minutes of your time. You will receive no direct benefit from taking part in this study. However, the information that is collected during this study will give us a better understanding of who our listeners are, and why they choose to listen to TWiP. We can use this understanding to make TWiP even better! This is an academic study and we aim to disseminate our findings to the wider public, including you. For example, we'll have a conversation about the findings on a future episode of TWiP, we plan conference presentations and publication in a relevant academic journal The project has been reviewed and approved by the University of Glasgow College of Medical, Veterinary & Life Sciences Ethics Committee. Application 200250013 You can find the study, detailed participant information, and consent information here:  TWiP study – information and survey

Today we chat with actor/musician Shane Wilson and dive into what inspiration and the love of creativity can make happen! From music to movies, Shane is a new talent in the industry and he explains his drive, his determination, his mindset and how it's attributing to his early success!Join us live on Facebook and YouTube Wednesday evenings at 5pm PST.Or follow this podcast on Spotify, Apple Music, Amazon Music and anywhere you get your podcasts!

In this episode of the Wine and Gold Talk podcast, Ethan Sands and Chris Fedor dive into the Cavaliers' puzzling run of slow starts and what might fix them — from possible rotation tweaks to the looming boost of Darius Garland's return. They break down the offense's stagnation and why Evan Mobley's stalled growth remains the biggest obstacle between Cleveland and real championship credibility. The guys also explore the noticeably more serious tone around the locker room this season, pointing to injuries, heightened expectations, and the missing spark of Garland's infectious joy. Learn more about your ad choices. Visit megaphone.fm/adchoices

Episode 2684 - Will gold continue to go up? The AIPAC mess? Wall Street scared? Infectious disease on the rise? What is the exchange stability fund? The greed of the entities that run the planet is never ending . Funny green show today!

Dallas Cowboys defensive end Marshawn Kneeland died on Thursday from an apparent self-inflicted gunshot wound. He was 24. In other news, the Federal Aviation Administration is planning on reducing flights at DFW International Airport, Dallas Love Field and a swath of other major U.S. airports in an unprecedented move as the ongoing government shutdown wreaks havoc on the aviation sector; a federal appeals court ruled Thursday that a previously blocked law designed to ban public drag performances can now go into effect. A panel of judges on the 5th U.S. Circuit Court of Appeals reversed a 2023 ruling from a Houston federal judge that had blocked enforcement of the law indefinitely; and a joint committee of Dallas City Council members voted unanimously Thursday to shelve a proposal that would have reimbursed the city for allowing police officers to help enforce federal immigration laws. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Episode NotesEpisode 95: Matthew 8 - Using Infectious Skin Diseases for OutreachNovember 1, 2025 - Host: Dr. Gregory HallIn this episode we'll dive into a particular formula (3 stories of healing followed by a call to discipleship) that Matthew uses to present Jesus' ministry. When we're done, you might ask if infectious skin diseases could be a part of your church's outreach ministry!Resources Referenced and/or Read:The list of Lepers in the Bible is pretty short:  Exod 4 - Moses' hand became leprous as snow, as if he had a skin disease, after he encountered God at the burning bush.Numbers 12:10 - Miriam, sister of Moses, became leprous when she spoke against Moses' leadership.Naaman - 2 Kings 5 - Elisha sent a messenger to him saying, “Go and wash in the Jordan seven times, and your flesh will be restored to you and you will be clean.”Gehazi, the servant of Elisha - 2 Kings 5:20Joab - 2 Samuel 3:292 Kgs 15; 2 Chr 26  - Uzziah [Azariah], king of Judah, was punished with a skin disease after he went into the temple of the Lord so that he might burn incense.Simon the Leper - Matthew 26:6-13 and Mark 14:3-9Three gospels likely share the same event: Matthew 8:2-4 - unnamed, Mark 1:40-45 - unnamed, Luke 5:12-16 - unnamedLuke 17:11-21 - 9 unnamed Jews - one unnamed SamaritanMatt 11:1-6 - When John the Baptist was imprisoned, John asks if Jesus is the Expected One… and in his response Jesus mentions several miracles associated with his ministry including “the lepers are cleansed”.Show Music:Intro/Outro - "Growth" by Armani Delos SantosTransition Music - produced by Jacob A. HallPodcast Website:The All-America Listener Challenge Updates: https://rethinkingscripture.comMy New Podcast Studio... The Upper Room: https://rethinkingscripture.com/podcast-episodes/More information about The Homes and Help Initiative: https://rethinkingscripture.com/homes-help-initiative/Sister site: RethinkingRest.comRethinking Rest... the Book is now available. The Rethinking Rest audiobook is available only on Audible: More information: https://rethinkingrest.com/the-book/Social Media:Facebook: https://www.facebook.com/RethinkingScripture Twitter: @RethinkingStuffInstagram: Rethinking_ScriptureYouTube Channel: https://www.youtube.com/channel/UC6YCLg2UldJiA0dsg0KkvLAPowered and distributed by Simplecast.

Description:  Hosts Roz and Dr. Sanchez-Fueyo are joined by Christie Rampersad to discuss the key articles of the November issue of the American Journal of Transplantation. Christie Rampersad is clinical associate, in the Division of Nephrology at the University of Toronto in the Ajmera Transplant Centre [03:45] The early impacts of an attempt to standardize kidney procurement biopsy practices [13:40] The current state of simultaneous heart-liver transplantation in the United States [20:11] Engaging patients in organ transplant listing meetings: A survey study [37:32] Single-cell transcriptional landscape of liver transplant rejection reveals tissue persistence of clonally expanded, treatment-resistant T cells [45:32] Infectious disease surveillance and management in clinical xenotransplantation: Experience with the first human porcine kidney transplant

Mösquitos, Underground astronauts, Infectious fear, UberCheats, Feather caper, Pearlescent cement, Stress gestures. Jennifer, Angie, Way, and Bradley discuss the curated links for the week of 10/31/2025. Please consider supporting this ad-free content on Patreon.

Infectious disease experts are raising the alarm over a concerning increase in antibiotic resistance, with rates increasing by more than 40% in just seven years. But the over-prescription of antibiotics is only a small part of the problem... In this episode of The Briefing, Natarsha Belling is joined by infectious diseases expert Sanjaya Senanayake, who explains why antibiotics are not working on so many serious diseases and the urgent action that’s needed. Headlines: President Donald Trump has ordered the US Department of War to resume testing of nuclear weapons, the family of a teenage cricketer killed in a training accident has issued a heartbreaking statement, and Nationals MP Barnaby Joyce has denied allegations that he verbally abused a female staffer. Follow The Briefing: TikTok: @thebriefingpodInstagram: @thebriefingpodcast YouTube: @TheBriefingPodcastFacebook: @LiSTNR Newsroom See omnystudio.com/listener for privacy information.

This episode is sponsored by AyurLight Candles. Illuminate your home and your life! These products make a wonderful gift to someone or to yourself! Add AyurLight Candles to your traditions this festive season! www.ayurlightcandles.comGet my Gratitude Journal on Amazon! Elevate your morning/evening routine: https://www.amazon.com/Gratitude-Journal-Rashi-Stephens-Charlton/dp/B0CWYHDTGPTry Mary Ruth Organics Supplements! Get 15% off your order with my code: MRORASHI at checkout on www.maryruthorganics.com.Attn busy moms! Become your best self with my Becoming That Mom guidebook - on sale now! *****Welcome back to Catwalk Through Life!Today, I chat with Bollywood's Journalist & TV Host, Abhishek Dutta. He is a face all the Bollywood bigwigs want to talk to, he's been part of the industry for many years, and is here sharing his ups and downs, what made him successful and an inside look at his job! We also chat about his passion in health and wellness and how he prefers to reach his fitness goals naturally. Abhishek shares his thoughts on fatherhood, balancing it all, and so much more. It was wonderful catching up with him after years and bringing to you his amazing energy! Thank you all for listening to Catwalk Through Life! I hope you enjoy this episode!*****Helpful Links:Abhishek Dutta Instagram Page: https://www.instagram.com/abkdutta?igsh=MXhtYjM2ZGt3Y2V2Ng==Catwalk Through Life Instagram Page: https://www.instagram.com/catwalkthroughlife Rashi Stephens-Charlton Instagram Page: https://www.instagram.com/rashistephens Becoming That Mom Guidebook: https://stan.store/CatwalkThroughLife/p/becoming-that-mom-guidebookGratitude Journal on Amazon: https://www.amazon.com/Gratitude-Journal-Rashi-Stephens-Charlton/dp/B0CWYHDTGPCatwalk Through Life Facebook Group: https://www.facebook.com/groups/726602181696067Catwalk Through Life Blog: https://www.catwalkthroughlife.com *****Disclaimer: Please know that any advice given is just a suggestion and what has worked for us. This is not medical advice for anyone in particular. We are not medical professionals. Please consult your doctor for medical questions and use your best judgement on what's best for you. The intent behind this episode is to entertain and merely share information! :)

Hi, I'm John Sorensen, President of Evangelism Explosion International, and you're listening to Share Life Today. Brad Hutchcraft has seen what happens when we take Jesus' command to share the Gospel seriously. He said, “It's when we share Jesus with someone that we get to see the impact it has on their lives and how the lights come on for someone. And it's infectious.” When you tell someone about Jesus and watch their life change, it fuels your own faith. The joy of seeing God work in another person's heart is contagious—it makes you want to keep going. So today, let's share Jesus with someone who needs the hope found only in Him. It's exciting to join God in the work He is already doing. And when you step out in faith and share the Gospel, you never know how God might use your obedience to ignite faith in another life. For resources to help you share your faith and to watch the full interview with Brad and Doug Hutchcraft, visit sharelife.today.

Infectious disease physician Tyler B. Evans discusses his article "Meeting transgender patients where they are: a health care imperative." Tyler, an infectious disease specialist and author of Pandemics, Poverty, and Politics: Decoding the Social and Political Drivers of Pandemics from Plague to COVID-19, shares striking data on violence, mental health, and HIV disparities affecting transgender and nonbinary communities worldwide. He recalls formative patient experiences that reshaped his understanding of gender affirming care, emphasizing the need to move beyond outdated disease models and rigid medical training. Tyler explains why social determinants from housing to acceptance are critical to health outcomes, and why true reform begins with meeting patients where they are. Listeners will gain practical insights into building compassion driven systems that improve health equity and save lives. Our presenting sponsor is Microsoft Dragon Copilot. Microsoft Dragon Copilot, your AI assistant for clinical workflow, is transforming how clinicians work. Now you can streamline and customize documentation, surface information right at the point of care, and automate tasks with just a click. Part of Microsoft Cloud for Healthcare, Dragon Copilot offers an extensible AI workspace and a single, integrated platform to help unlock new levels of efficiency. Plus, it's backed by a proven track record and decades of clinical expertise, and it's built on a foundation of trust. It's time to ease your administrative burdens and stay focused on what matters most with Dragon Copilot, your AI assistant for clinical workflow. VISIT SPONSOR → https://aka.ms/kevinmd SUBSCRIBE TO THE PODCAST → https://www.kevinmd.com/podcast RECOMMENDED BY KEVINMD → https://www.kevinmd.com/recommended

Did you know the trillions of microbes in your gut might shape everything from your immune system to your mental health—and even how you recover after an infection?

If you think leadership is about the title on your résumé, the results you deliver, or the strategies you execute, it's easy to see why. We've been taught to measure great leadership by performance. However, the truth is that people often don't follow the title. They follow the energy.  In this episode, I share 10 brain-backed practices that rewire your brain for joy, resilience, and connection while transforming how others experience you as a leader. From gratitude and laughter to listening deeply and celebrating wins, you'll learn how simple daily habits can create powerful ripple effects in your work, your relationships, and your community. Our mission is to help you become unstoppable, enabling you to do your best work of your career while enjoying more inner peace and freedom. Head to ritahyland.com and sign up to receive podcast announcements and exclusive tips to unleash more of your creativity, productivity, and ingenuity in your work and at home.  If this episode was helpful for you…  Share it with someone who will also benefit from hearing it.  That way, we all improve. Also, be sure to leave a review on Apple Podcasts, letting me know what you enjoy about Playing Full Out and any questions you have.  Your topic may be used as the subject for a future episode! Show Notes: https://www.ritahyland.com/positively-infectious-leader  Connect with Rita on LinkedIn: ★Rita (Wetterstroem) Hyland★  

Hour-2 (9.9.2025) 

Duane Kuiper joins Murph & Markus to discuss the offensive outburst at Oracle Park last night, Logan Webb reaching 200 strikeouts this season, & Drew Gilbert's infectious energy See omnystudio.com/listener for privacy information.

Duane Kuiper joins Murph & Markus to discuss the offensive outburst at Oracle Park last night, Logan Webb reaching 200 strikeouts this season, & Drew Gilbert's infectious energy See omnystudio.com/listener for privacy information.

Giants Insider for The Sports Leader & Senior Writer for The Athletic, Andrew Baggarly joins Murph & Markus to discuss Drew Gilbert's breakout weekend & his infectious energy in the clubhouseSee omnystudio.com/listener for privacy information.

Giants Insider for The Sports Leader & Senior Writer for The Athletic, Andrew Baggarly joins Murph & Markus to discuss Drew Gilbert's breakout weekend & his infectious energy in the clubhouseSee omnystudio.com/listener for privacy information.

The American Academy of Pediatrics is breaking with the CDC for the first time in decades by continuing to recommend Covid-19 shots for infants and young children. By contrast the CDC, under Health and Human Services Secretary Robert F. Kennedy, Jr., is no longer recommending the vaccine for healthy kids. Infectious disease expert Michael Osterholm joins us to help make sense of the conflicting messages. We'll also get his thoughts on federal cuts to vaccine research funding, and our readiness for future pandemics. Guests: Dr. Michael Osterholm, epidemiologist; director of the Center for Infectious Disease Research and Policy, University of Minnesota Learn more about your ad choices. Visit megaphone.fm/adchoices