Podcasts about mrsa

Bacterium responsible for difficult-to-treat infections in humans

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Best podcasts about mrsa

Latest podcast episodes about mrsa

RADIO4 MORGEN
Tirsdag d. 13. maj kl. 9-10

RADIO4 MORGEN

Play Episode Listen Later May 13, 2025 55:09


(01:00): Krænkende kørelærere skal stoppes: SF kalder transportministeren i samråd. Medvirkende: Mads Olsen, transportordfører SF. (15:00): I snart seks år har Rigshospitalet kæmpet med et udbrud af MRSA på neonatalafdelingen. Medvirkende: Christoffer Buster Reinhardt, formand for sundhedsudvalget, regionsrådsmedlem (C), Region Hovedstaden. (30:00): Rusland opruster nær Finland og Norge. Medvirkende: Flemming Splidsboel, seniorforsker ved Dansk Institut for Internationale Studier, DIIS. (40:00): Nyt udspil fra Borgernes Parti: Der skal være fuld åbenhed om partiernes økonomi. Medvirkende: Lars Boje, formand for Borgernes Parti og medlem af Folketinget. Værter: Anne Philipsen & Nicolai DandanellSee omnystudio.com/listener for privacy information.

Munch My Benson: A Law & Order: SVU Podcast
46 - It Sucked That D-Bag Rape Boy Was Gonna Be the Last Guy to Lay Pipe in McCallum County (S11E16 Witness)

Munch My Benson: A Law & Order: SVU Podcast

Play Episode Listen Later May 6, 2025 78:16


Adam's Paternity Leave continues, so we're going back to the well to pull an episode that feeds our Benbot passion. Patreon payments are frozen for the time being. A few resourceful new Munchies have figured out a work-around where you can join as a free member and upgrade from there to a paid account which charges you for one month and unlocks the back catalog behind the respective tier of the paywall. After that first payment, you won't be charged again until we're dropping new content (which we'll warn everyone is coming), so if you want more of this it can be had, along with access to the fully uncut episodes from 100 to present and Movie Club episodes.Sometimes the Randomizer giveth; sometimes it taketh away. It's sort of like SVU that way. This week it gave an episode that takes us all on a wild ride from a stairwell in Chelsea to the grim realities of life in the Democratic Republic of Congo. Along the way, jealousy abounds, Benbot enjoy a romantic candlelit dinner, Adam breaks down the past 150 years of strife in the Congo, Amazing Grace and Chuck is deduced to have done some ripping from the headlines, no one wants to believe our victim—Lainie McCallum, played by Diora Baird—and a cut hand yields some unexpected outcomes. The Munchie Boys tackled “Witness” (S11E16), so hold on to your butts.Music:Divorcio Suave - "Munchy Business"Thanks to our gracious Munchies on Patreon: Jeremy S, Jaclyn O, Amy Z, Diana R, Tony B, Zak B, Barry W, Drew D, Nicky R, Stuart, Jacqi B, Natalie T, Robyn S, Christine L, Amy A, Sean M, Jay S, Briley O, Asteria K, Suzanne B, Tim Y, John P, John W, Elia S, Rebecca B, Lily, Sarah L, Melsa A, Alyssa C, Johnathon M, Tiffany C, Brian B, Kate K, Whitney C, Alex, Jannicke HS, Roni C, and Nourhane B - y'all are the best!Be a Munchie, too! Support us on Patreon: patreon.com/munchmybensonBe sure to check out our other podcast diving into long unseen films of our guests' youth: Unkind Rewind at our website or on YouTube, Apple Podcasts, or wherever you listen to podcastsFollow us on: BlueSky, Facebook, Instagram, Threads, and Reddit (Adam's Twitter/BlueSky and Josh's BlueSky/Letterboxd/Substack)Join our Discord: Munch Casts ServerCheck out Munch Merch: Munch Merch at ZazzleCheck out our guest appearances:Both of us on: FMWL Pod (1st Time & 2nd Time), Storytellers from Ratchet Book Club, Chick-Lit at the Movies talking about The Thin Man, and last but not least on the seminal L&O podcast …These Are Their Stories (Adam and Josh).Josh debating the Greatest Detectives in TV History on The Great Pop Culture Debate Podcast and talking SVU/OC and Psych (five eps in all) on Jacked Up Review Show.Visit Our Website: Munch My BensonEmail the podcast: munchmybenson@gmail.comThe Next New Episode Once We're Back from Adam's Paternity Leave Will Be: Season 16, Episode 14 "Intimidation Game"Become a supporter of this podcast: https://www.spreaker.com/podcast/munch-my-benson-a-law-order-svu-podcast--5685940/support.

Henrico News Minute
Henrico News Minute – May 5, 2025

Henrico News Minute

Play Episode Listen Later May 5, 2025 5:11


Henrico officials issue 18-page report proposing changes to data center development; Henrico Doctors' Hospital dealt with MRSA outbreak in NICU unit for three years; former Henrico Doctors' Hospital nurse accused of abusing infants is stripped of her nursing license; county reports incidents of people posing as Public Utilities employees.Support the show

Prison Radio Audio Feed
MRSA Infection — Krystal Clark

Prison Radio Audio Feed

Play Episode Listen Later Apr 29, 2025 3:02


infection mrsa krystal clark
The EMJ Podcast: Insights For Healthcare Professionals
Episode 250: Infectious Disease Diagnostics: Superbugs, Zoonotic Threats, and the Next Pandemic

The EMJ Podcast: Insights For Healthcare Professionals

Play Episode Listen Later Apr 24, 2025 50:58


In the second episode of our miniseries on infectious disease diagnostics, Jonathan is joined by molecular epidemiologist Rodney Rohde, Regents' Professor at Texas State University, USA. Together, they explore diagnostic innovations in the fight against antimicrobial resistance, gaps in zoonotic disease detection, and the persistent challenge of vaccine hesitancy. Timestamps: 00:00 – Introduction 01:45 – Breakthroughs in molecular diagnostics 08:30 – Diagnostic tools to combat superbugs 14:18 – Can bacteriophages replace antibiotics? 19:04 – Controlling rabies and hantavirus 28:33 – Diagnostic successes and failures from COVID-19 35:22 – How do we address vaccine hesitancy? 44:10 – Preparing for the next pandemic 47:03 – Rohde's three wishes for healthcare

Event Horizon
Ep 101 - Can Cars Run On Water - The Stanley Meyer Story

Event Horizon

Play Episode Listen Later Apr 10, 2025 41:27


Ep 101 - Can Cars Run On Water - The Stanley Meyer Story Welcome to this episode of Event Horizon. Today, we unravel the fascinating and controversial story of Stanley Meyer's water-powered car—a revolutionary invention he claimed could run on nothing but water. Born on August 24, 1940, Stanley Allen Meyer, alongside his twin brother Stephen, designed a device called the "water fuel cell." This so-called perpetual motion machine was said to replace gasoline with water, leading to incredible claims of a dune buggy journey from Los Angeles to New York on just 22 gallons of water.Meyer asserted that the U.S. government and military offered him millions to acquire his patent—offers he refused as he sought to commercialize his invention. However, in 1996, before production could begin, Meyer faced a shareholder lawsuit, and an Ohio court declared his claims fraudulent.Yet, the drama didn't end there. On March 21, 1998, while meeting potential investors at a local restaurant, Meyer drank a sip of cranberry juice and suddenly fled the table, clutching his throat. His chilling final words? “They poisoned me.” Was Stanley Meyer silenced for his groundbreaking technology, or was this a tragic coincidence? And do governments really have the power to seize revolutionary patents from private inventors? These burning questions and more await in this episode. Tune in to uncover the full story—and don't forget to subscribe!Join The Community Follow us on:Facebook at https://www.facebook.com/quantumAIradioTwitter (X) at @EventHo14339589Instagram at @EventHorizonEmail at mpeter1896@gmail.com   Subscribe To My Other Podcasts:Movie Reviews from the Edge - https://www.spreaker.com/show/movie-reviews-from-the-edgeThe Mark Peterson Show - https://www.spreaker.com/show/the_mark_peterson_show      Support the Show Did you know you can support the podcast by joining the Spreaker Supporter Club? For as little as $2.00 per month, you can help me grow the show and produce more episodes.  Go to the show page on Spreaker and click on the Supporter Club!     You can also make one-time donations at my CashApp or Paypal:CashApp - $mpeter1896PayPal – mpeter1896@gmail.com Buy My New Book I have a new book!  It is called Career Coaching Xs and Os: How To Master the Game of Career Development.  Transform your career trajectory with insider knowledge and actionable advice, all packed into one game-changing guide.     Get your copy on Amazon at https://a.co/d/f7irTMLSources:https://www.reddit.com/r/WeirdWheels/comments/t1ehiu/stanley_meyers_water_powered_car_the_car_was_said/?rdt=41987http://www.top-alternative-energy-sources.com/stanley-meyer.html https://slate.com/technology/2018/05/the-thousands-of-secret-patents-that-the-u-s-government-refuses-to-make-public.html https://tcct.com/news/2020/11/the-mysterious-death-of-stanley-meyer-and-his-water-powered-car/?srsltid=AfmBOooD5NB4hEtrCsmDcM3FpSnW_mVybUkGuMS_86mRrpPDhJ7IJhNUhttps://www.bbc.com/news/business-68534703 https://www.npr.org/2025/03/21/g-s1-55175/whistleblower-john-barnett-lawsuit-boeing#:~:text=The%20family%20of%20John%20Barnett,to%20take%20his%20own%20life.%22 https://www.seattletimes.com/business/whistleblower-josh-dean-of-boeing-supplier-spirit-aerosystems-has-died/https://www.nhs.uk/conditions/mrsa/#:~:text=MRSA%20usually%20lives%20harmlessly%20on,it%20spreads%20inside%20the%20body.Become a supporter of this podcast: https://www.spreaker.com/podcast/event-horizon--2860481/support.

Hungry Dog Barbell Podcast
Dwight Sheehan

Hungry Dog Barbell Podcast

Play Episode Listen Later Apr 5, 2025 49:17 Transcription Available


Send us a textDwight Sheehan shares his journey from a 268-pound globo gym member to CrossFit affiliate owner, highlighting how an unexpected hospital stay changed his career trajectory and life path.• Started CrossFit in March 2021 after two gym members suggested he consider bodybuilding• Played offensive and defensive line in high school football, later becoming a high school coach• Lost significant weight in 2016, dropping from 268 pounds to 225 through running and diet changes• Developed a MRSA infection right before his first CrossFit comp • Decided to leave his unfulfilling mortgage job after his boss asked if he could work from the hospital• Took over CrossFit 717, growing membership from 65 to 110 members• Created "Nobody's Safe Athletics" as his coaching brand for individualized programming• Balances the dual challenges of being both a coach and owner• Preparing for the Master's Fitness Championships qualifier after placing fourth by half a point last year

The Pursuit of Health Podcast
Ep70: A Patient Advocacy Approach to Medical Errors, Hope and Systematic Change w/ Rosie Bartel

The Pursuit of Health Podcast

Play Episode Listen Later Apr 4, 2025 54:22


A conversation with Rosie BartelNurturing the patient-physician partnership is the only way to heal healthcare.Sharing her lived experience with openness and honesty is Rosie Bartel, a patient advocate and survivor of preventable medical error. Since contracting MRSA after a routine knee replacement surgery, Rosie has channelled a hugely difficult and prolonged healthcare experience into a mission for systemic change.As she states, patient safety is a bipartisan issue, and we must ensure continued collaboration and communication between physicians, policymakers, executives and most importantly, patients themselves.——We spoke about Rosie's journey, why she believes patient advocacy is so important, the importance of breaking down silos that prevent communication, how patients can become their own advocates, and her solutions for developing relationships in healthcare that are rooted in trust.Follow me on Instagram and Facebook @ericfethkemd and checkout my website at www.EricFethkeMD.com. My brand new book, The Privilege of Caring, is out now on Amazon! https://www.amazon.com/dp/B0CP6H6QN4

American Conservative University
Man Says He Visited Heaven, Met Jesus During Near-Death Experience

American Conservative University

Play Episode Listen Later Mar 22, 2025 31:20


Man Says He Visited Heaven, Met Jesus During Near-Death Experience Watch this video at- https://youtu.be/3FQmcCFZ8Ng?si=x4U0Eezqh21CuDDg CBN News 2.28M subscribers 123,685 views May 16, 2024 Randy Kay's "afterlife" experience still leaves him visibly emotional as he recounts details of visiting heaven, meeting Jesus, and returning to share his harrowing journey. Kay, author of the book, "Heaven Stormed: A Heavenly Encounter Reveals Your Assignment in the End Time Outpouring and Tribulation," told CBN News he was once a denier of near-death experience claims — until he faced his own purported heaven journey. He recalled his own afterlife experience, which began with a sore calf. At first, he thought he had strained a muscle, but while working out and going on a bike ride, his calf began to swell. "I was able to make it back home and then went to the doctor to get an anti-inflammatory prescription, and lo and behold, when I pressed my heel into the floor as the doctor had suggested, I collapsed," Kay said. "And I was rushed to the emergency room." It turns out, the pain and swelling were due to seven blood clots that had formed. He then contracted Methicillin-resistant Staphylococcus aureus (MRSA), a drug-resistant bacteria. "The doctor said I was a walking dead man," Kay said. "And then the septic shock which entered into my body caused a traffic jam in my vessels, my vascular system." The chaos landed Kay in a dire situation — one that he believes sent him to heaven. "Everything went dark initially and the next moment of recall, I was looking down on my body," he said. "I was being pulled by this light. I know that sounds cliche, almost, but it's absolutely true." Kay continued, "I was in a kind of very vague, ethereal space initially where I saw these figures in front of me, and they were warring against each other. There's no other way of putting it." After his return from his after-death experience, Kay discerned he was watching spiritual warfare play out. Regardless of what people choose to believe, Kay's physical body was dead at this point, making these memories and claims quite fascinating. "My heart had stopped," he said, noting that hospital records indicate he was clinically dead for 30 minutes and 49 seconds. During that time, Kay believes he was experiencing heaven, noting he was aware that her was himself but suddenly was seeing and visualizing the world quite differently. "I was seeing things, hearing things beyond which I would be able to do otherwise in my body," he said.

HIListically Speaking with Hilary Russo
Ep182 - Heart Strong: The Power of Her Pulse with guest Stacey Grant

HIListically Speaking with Hilary Russo

Play Episode Listen Later Feb 26, 2025 31:11 Transcription Available


It was a recipe for disaster. In 2023, Stacey Grant was rushed to the hospital with a MRSA infection. It was in her bloodstream, in her lungs, and most likely around her heart. To say she dodged a bullet is an understatement. Because many do not. Cardiovascular disease kills more women than all forms of cancer combined and yet only 44% of women recognize that cardiovascular disease is their greatest health threat. On this episode of the HIListically Speaking Podcast, we're changing that for you and your heart.   CONNECT WITH STACEY http://www.mainlinevideostudio.com https://www.instagram.com/staceymgrant https://www.linkedin.com/in/staceygrant/ SUPPORT STACEY AS AN AHA WOMEN OF IMPACT https://bit.ly/4hUZS0o ⁣ Need a Podcast Mic - I'm Using Shure MV7+ Mic  ⁣ https://amzn.to/3ZBaXNm (Amazon)⁣   ⁣As an Amazon Associates I earn from qualifying purchases ⁣ ⁣ DISCOVER HAVENING TECHNIQUES TRAININGS & WORKSHOPS⁣ https://www.hilaryrusso.com/training   ⁣GET BRAIN CANDY DELIVERED TO YOUR INBOX⁣ ⁣ https://www.hilaryrusso.com/braincandy ⁣ BOOK HILARY FOR YOUR NEXT EVENT OR ATTEND!⁣ https://www.hilaryrusso.com/events⁣ ⁣ CONNECT WITH HILARY⁣ https://www.hilaryrusso.com⁣ https://www.linkedin.com/in/hilaryrusso⁣ https://www.instagram.com/hilaryrusso⁣ https://www.youtube.com/hilaryrusso⁣ https://www.hilaryrusso.com/podcast⁣ ⁣ MUSIC by Lipbone Redding⁣ https://www.lipbone.com/

Good Day Health
Pneumonia and MRSA In Adults

Good Day Health

Play Episode Listen Later Feb 25, 2025 35:58


Tuesday, February 25 - Host Doug Stephan and Dr. Ken Kronhaus of Lake Cardiology (352-735-1400) cover a number of topics affecting our health. First up, the severity of this year's flu, a drastic increase of adults being diagnosed with pneumonia and MRSA, and why getting more rest when you're sick is beneficial to your immune system, especially when going to work is only spreading your illness around. Then, the conversation shifts to Robert F. Kennedy Jr.'s confirmation as the Secretary of Health and Human Services and where he might start first in investigating harmful food ingredients and additives, the safety of childhood vaccines and anti-depressant drugs, harmful herbicides, and effects of electromagnetic radiation. Additionally, Doug and Dr. Ken discuss that latest information on the Avian Flu, why there is a rise in lung cancer amongst non-smokers, a connection in depression and long-term health issues relating to heart disease, a focus on the rise of gambling addiction, and the differences between weight-loss drugs and which Dr. Ken prefers. Lastly, Dr. Ken answers your questions, including how you would know you're low on Vitamin D, heart-healthy tips Dr. Ken shares with his own patients at his clinic in Mount Dora, FL, and why you need to keep up with regular checkups with your doctor and pay attention to any new symptoms you notice. Website: GoodDayHealthShow.comSocial Media: @GoodDayNetworks

The Numlock Podcast
Numlock Sunday: Olivia Walch on the science of sleep

The Numlock Podcast

Play Episode Listen Later Feb 2, 2025 37:00


By Walt HickeyWelcome to the Numlock Sunday edition.This week, I spoke to Olivia Walch, author of the brand-new book Sleep Groove: Why Your Body's Clock Is So Messed Up and What To Do About It.Olivia's a good friend of mine and I've been hearing about her research and her work for years, and now she's finally got a whole book diving into why ideal sleep is more than just the eight hours number we hear so much about. It's a delightful book with all sorts of cool insights that can have major impacts on your life and health. We spoke about the human body's numerous circadian rhythms, why sleep regularity is more important than sleep duration, and why permanent daylight saving time is a bad idea. Walch can be found at oliviawalch.com and the book can be found wherever books are sold.This interview has been condensed and edited. Olivia, thank you so much for coming on.I'm so delighted to be here.You are the author of the brand-new book Sleep Groove: Why Your Body's Clock Is So Messed Up and What To Do About It. It's a really, really fun book. It covers a lot of the science behind sleep and actually has some pretty surprising stuff in there for folks who are interested in their own sleep health.You have a really interesting story about how you even fell into being interested in the science behind sleep. You did a sleep study at some point in grad school that changed your life, it sounds like.Well, you knew me before then. We were in college together.Each diabolically bad at sleeping.I would give each of us a failing grade — you maybe a lower grade than me. I was bad, but you were exploring new horizons of bad, like with polyphasic sleep.I tried it once. It was such a bad idea.Maybe a D, D-minus. I knew when I went to grad school something had to change. I was not sleeping; I was not making new memories; I was getting sick. I got MRSA in college and I wonder all the time, was it because my immune system was like a frail Cheeto trying to hold the door closed to the germs? But at the time, I thought at college, you have to do everything. You have to be in every club and miss no opportunity for an experience. And I now remember no experiences from that time period.In grad school, I decided I was going to sleep more. I did, but I didn't actually notice that huge of a difference with fewer things filling my schedule, even though I was sleeping more. It was better, but it wasn't that much better. It took a sleep study in which I had to keep a really regular bedtime and researchers were spying on me. They would know if I didn't, because I was wearing a device, ye olde Jawbone, which is not even a thing anymore. For months, I went to bed at 11:30 every single night.The changes were so profound. I didn't just instantly fall asleep at 11:30, though that did happen. I got faster, I lost weight, skin conditions cleared up. In every dimension, my life was better. And the thing that had shifted was not really sleep duration, but sleep regularity.You get at this idea early in the book. There's this very common number that everybody associates with the right thing to do about sleep, which is that you should sleep for eight hours. The book goes the next level deeper, looks at some of the other dimensions of sleep, and it turns out that eight hours is good, that's a good thought to keep in your mind, but it's really the rhythm. What is the conceit here? Why are rhythms important when it comes to this stuff?Our understanding of sleep health is so fixated on duration that there's a creepypasta on Reddit that goes, "Oh, these Russians were kept awake and they went crazy." The creepypasta has always been funny to me because it's like, "Yeah, and after five days of no sleep, they started eating their own organs." (Spoilers for the Russian sleep experiment creepypasta.) Yet we've kept lots of people up for five days and they don't start eating their organs. We have this conception in our minds that losing sleep duration is going to be really bad. It's not good, but it also doesn't make you self-cannibalize after five days of no sleep.That definition of sleep health is woefully inadequate. The movement in the sleep field is higher dimensional. There are more things that matter to sleep health. There's this big, long list of things. People say you should think about how many times you wake up in the middle of the night, and you should think about how alert you feel during the day.All of those are great, but they're not memorable. People don't keep two things in their head, let alone five. I'm trying to get people to keep two, which is duration and regularity, as the latitude and longitude of sleep health. You don't say Madrid and New York are close together just because they have the same latitude; longitude also matters. You shouldn't say somebody who sleeps eight hours a night is healthy if they have horrible regularity. That's a case where they are probably pretty far from health, just like New York and Madrid are pretty far from each other.A lot of this comes down to circadian rhythms. What are they in your view? What kind of bodily processes are governed by them?The whole shebang. The problem with circadian rhythms is that their UI is terrible. People talk about the circadian rhythm, but that's not really right because circadian rhythms are plural. Sleep is under the subhead of circadian rhythms, but so is everything else in your body: when you're strongest, when you metabolize food, when your immune system peaks, when you repair DNA. There's this real problem. I think that because circadian rhythms are kind of everything, people just say, "You know, the rhythms." This leads to everyone who doesn't study this all day, every day, walking around having no idea what they are and just thinking it's probably the same thing as sleep.Your body has an internal clock, and it schedules things according to when it thinks you need to do more or less of them. That clock is set by your light exposure, and in modern life, we get light whenever we want it, which is not particularly traditional or natural.Circadian rhythms developed as a process because we live on Earth, right? We know there's a certain amount of daylight and when certain things should happen, and we evolved specifically to have a circadian rhythm.Yes. The circadian rhythm is so tuned to Earth that if you put us on a planet with 28-hour days, we probably wouldn't be able to adjust. We would basically continue to have close to a 24-hour period in our rhythms that would continue, even though the sun on this planet would be up and down at different times. It's baked into us, and it's the case that there's just stuff in your body at some times that isn't there at other times. The hormone melatonin, for example. If I made you spit into a tube right now, you would not have melatonin in your spit.We're speaking in the middle of the afternoon. It's very, very bright outside.No melatonin. But 10 hours from now? Different story. The thing to imagine is just a bunch of switches in your body getting flipped on and off depending on the time of day, which has massive implications for health, drug efficacy, how you feel, and people have lost their connection to that. Number one, we can have light whenever we want it, so our rhythms are squished relative to where they otherwise would be. But number two, I think we don't have a great way of talking about rhythmic health, which my book tries to address. I'm sure there's much better I can do and other people can do in the future, but this is my first stab at it.You get at this inflection point where so much of these functions are the result of, if not tens of thousands, then millions of years of evolutionary processes really locking us into a day/night process. Then you have the emergence of electricity, and a lot of your book reflects on how that's actually changed the way our bodies work, in ways we wouldn't ordinarily expect. What are some of those ways?I would say signs of rhythms having different effects on your body in the winter versus summer. Any study that reports on those, I'm always very cautious about, because I was involved in a study where we looked at Twitter patterns over the course of the year. We wanted to know if people tweeted differently at different times of the year in a way that reflected the sun and circadian rhythms, and we saw this pretty incredible trend where things seemed to really shift around the spring. Daylight saving time is happening then, the sun is changing, so you think, okay, maybe it's related to the sun.Then we dug a little more closely into the data and saw that the entire effect was just driven by people going on spring break. You would see that people tweeted later when they were on break because they were sleeping in. The fact that we have light available to us whenever we want it and we're not just sitting around in the dark at 6 p.m. in December with nothing to do means that we're in a sort of perpetual summer. We have light as late as we want, as long as we want, and that's stepping on these natural rhythms that would be emerging in the absence of that light.The title of the book is Sleep Groove, and sleep groove is actually a thing you talk about quite a bit in the book. It's getting locked into a really strong, robust, resilient rhythm, and there are lots of advantages to having that. What are some of the advantages that you have by having that rhythm, and what are some things that can go wrong if you don't?I would say you die sooner. This is a brand-new result, that sleep regularity predicts dying better than sleep duration, but it does. Again, this definition of sleep health being how long you sleep would say, okay, shoot for eight hours on average, it doesn't matter when, and you're good.But if you actually look to see what predicts whether you die, the people who have the worst sleep regularity are highly correlated with dying younger, and it keeps coming out. This is in the last 18 months that connections are coming out between sleep regularity and hypertension, diabetes, mood disorders. The data was all there, but people weren't really looking at sleep regularity. We also didn't have as textured tools for defining sleep regularity as we do now, so that's another reason why it's coming out. But things that can go wrong without sleep regularity are all those bad things I listed.I should say that those are all correlations. You could say, well, maybe stressed people die earlier, and they're also sleeping irregularly as a sign of their stress. Except we also have studies where you put people on weird light schedules and you can watch a melatonin rhythm that's really robust just go away. They go 24 hours without making melatonin, which is weird. You've basically flattened their rhythm altogether.The mental image I always have in my mind for modern life is that we've taken rhythms that would be really high and pronounced — like, hey, now's the time to fix your DNA so you don't get cancer. Let's fix all our DNA right now. It's really clear period for fixing DNA — and you've stepped on it. Now it's like, well, I don't know. I guess it's the time to fix DNA? Maybe I'll do a little bit of that.The science is emerging. I don't want to overstate it, but I think there's a strong theoretical case for why the quashing of circadian amplitude is tied to a lot of bad things. The good thing is that more melatonin means you sleep better, feel better — basically my life after doing that one study.What's a situation where you have a strong circadian amplitude? A lot of light during the day? How do you get there?You do the same exact thing every day. I should say, I'm going to speak from a theoretical perspective because a lot of the experiments haven't been run yet. It's my collaborators and me who are calling for amplitude to be the new thing we go after, because sleep regularity is just circadian amplitude wearing glasses and a mustache. They pick up the same thing.What the theory says will get you the maximum circadian amplitude is to have a super bright day and get tons of daylight during the day, and then have a really, really dark night, and copy and paste that over and over again. That's basically it. I'm always think I should add other things for people to do, but it boils down to that.One of the challenges why people haven't discovered this on their own is that that's actually really hard to do in practice. Light at night is super fun, and we also have to work, and often work is indoors where there's just not as much sunlight.It really does seem like a problem of modernity. We've always had a way to illuminate the night, for all intents and purposes, but there's a vast gulf of difference between a candle and an incandescent light bulb, and then there's an even bigger difference between an incandescent light bulb and a full room of fluorescent light. There's been this subtle shift that we didn't notice over time, but our bodies did.You're speaking my language. This is exactly it: the creeping of light into every aspect of our life. Also, because it literally doesn't have mass, it feels immaterial, right? What, the photons are going to get you?And I don't think they will on a short time span. You can absolutely have a bad night of sleep. You can absolutely have disrupted sleep. People cross time zones. But it does add up over a lifespan, which is why we see sleep regularity being a better predictor of mortality than sleep duration. If you're highly irregular over your whole life, all these rhythms that would otherwise have been high metabolism, high DNA repair, robust ability to sleep, become flat and crappy and you get an accumulation of risk.So, a lot of what we've talked about is that there are lots of negative things when you're out of that appropriately phased kind of sleep. There are actually some really good things about being very attuned to that, too. You write in the book about athletics, about medicine. What are some of the ways we can actually gain quite a bit through knowing about this?By having a better sense of what our circadian time is. Conflict of interest disclosure, I do have a startup that tries to do this, but we'll be able to time drugs so that they're maximally effective and as least toxic as they can be.People sometimes go, okay, timing drugs as in you take sleep medication before you go to sleep. Sure, okay. But what if there were a drug that sometimes made your tumor shrink and at other times made it grow faster? That's a paper that came out in the last year. People aren't thinking about this. They're thinking about a 10% variation over the course of the day. They're not thinking about how this person's glioblastoma treatment didn't work because they took dexamethasone at the wrong time, and they died months earlier.I think the simplicity of the idea has started to act as a reason for people to not do it. They think, well, if timing actually mattered, somebody would have figured it out already. I won't be the one who wastes a bunch of time rediscovering what everyone else has. My stance is that we're just beginning to scratch the surface of all the things that can be controlled by timing, and the magnitude of the effects we can see.Imagine the drug I mentioned that accelerated tumor growth sometimes and squished it at others is standard of care. Everybody gets it with this particular type of brain tumor that it was studied in. Imagine you're testing a new drug and oh, it seems to work in these patients but it doesn't work in these other patients. Must not be a very good drug, so it gets ditched. It could be that that entire efficacy difference was driven by when they were taking this standard-of-care drug that everybody takes according to the clock, according to their body's clock. If you could just control for that, you could get more drugs making it through clinical trials.You even made a point that there's a good shift happening between notes saying you should take this pill in the morning, you should take the pill at night, and changing that to say you should take this pill after waking up or take this pill before you go to sleep. It's getting better at adequately describing the bodily conditions you should take pharmaceuticals under.Right. If you're a shift worker, you could be waking up at 3 p.m., for instance, and morning could be the worst time for you. You should take it when you wake up. Then again, if you're a shift worker, your rhythms are so funky that — I might be biased here — you should be using Olivia's cool app to track your circadian rhythms and know when to take all these different things.But yes, circadian medicine is all about timing your pills before you go to bed or after you wake up. It's also this idea of introducing grooves where we've removed the groove. An example would be that you have a sick kid and you can't feed them, so you put them on total parenteral nutrition, or TPN. They're getting fed through an IV, and the standard for that is to either do it overnight or do it just continuously, 24 hours a day. But if you think about it, if our whole bodies are rhythmic and we expect some things at some times and not at other times, and you're feeding them constantly, that's like being in the light all the time, which we would consider to be torture. If you put somebody in constant light, they are miserable.These researchers just changed it so they gave TPN only during the day, when the kids are awake and their metabolism is up and running. They were able to leave the hospital on average four days earlier because they weren't being force fed like a foie gras goose overnight. So, it's not just sleep grooves: it's food grooves, it's activity grooves, it's mood grooves, it's all these things. Acknowledging that they're rhythmic will lead to people being healthier.The medical stuff can get a bit in the weeds, but I thought it was really informative when you talked about U.S. Olympians going to Japan. You reflected on when folks went to Japan and how they trained there. There's actually a lot of performance that was hypothetically not being unlocked because people weren't being attuned to their circadian peaks. Do you want to talk a little about that?I was reading what people who are Olympians posted on their Instagram, imagining that we were friends. I saw somebody in the weight lifting category be like, "Can't wait to go to Tokyo in two days to compete!" They were fully adjusted or entrained to U.S. time, and they were going to do this trip to Tokyo that was going to massively disrupt their circadian rhythms. Then they were going to compete shortly after landing.Probably the reason for that is because it's really expensive to go and leave your life for a long period of time, and weight lifting isn't the moneybags, the dollar sign, of Olympic sports. But that probably wasn't the best for optimizing performance, to wait until right before you're supposed to go on and then try and lift something really hugely heavy — though it could have been.The thing is, when you travel, you get tired and you undergo jet lag because your light exposure is changing, but you also have a circadian rhythm in performance where people tend to do best in the evening. Around 5 or 6 p.m., you're strong and fast and can run far and lift heavy things. If in Japan, you were supposed to compete at 10 a.m., maybe what you want to do is not adjust and be really careful about staying on your old time zone for the first day you're there, so that your body is at 6 p.m. during Japan's local time of 10 a.m.When it's most suited to compete.Exactly, to lift a big, heavy thing.Exciting. You wrote a little about how there are two big peaks for performance over the course of a given day. What are those?People tend to be alert in the morning, and then they have a second wave of alertness as the day winds down. The way we think about that is that there are two forces that combine to make you feel sleepy: There's how much hunger for sleep you've built up, and then there's your circadian clock basically shaping the gravity. How heavy is gravity for you right now?In the morning, after you get over this initial wave of grogginess, you have the first wave of alertness and that's because you don't have any hunger for sleep. Imagine you're biking, and you just started biking so you're feeling fresh, you're okay. You haven't accumulated feeling tired from biking. In the middle of the day, though, you have accumulated some fatigue. You've been doing stuff with your brain and the circadian clock is not saying it's a great time to be alert. People often get sleepy in the middle of the day, like you would be sleepy if you'd been biking for four hours.Then later in the day, the circadian clock comes in and says it's time for you to be awake. You need to get your act together before the sun goes down or you might die. That's like the road you're biking on sloping downward. It becomes easier. It doesn't take as much effort to stay awake; it doesn't take as much effort to pedal. Your circadian clock is like, great, be alert. Do stuff in the latter part of your day up until close to your habitual bedtime, when the road starts to swoop up again.Then you basically hit the wall of, it's 3 a.m. I want to die. Why am I staying up super late in the year 2009 next to my good friend Walter? What are we doing? You push through that and you get on the other side, and the road starts to slant down again.It was really cool to see, because this speaks to my experience of being sleep deprived and going over the swing set. It's really cool that circadian rhythm still holds, and that's why you get that second wind in the morning and sleep deprivation madness or whatever you want to call it. You do still see that swing hold even if you get more and more sleep weight accumulating.Exactly.I want to talk about some of the studies that you covered, because they're very, very interesting, but I also want to talk about some policy implications. Two things stuck out to me. One was the conversation about daylight saving time and potentially going either permanent DST or permanent standard time. The other one that was super interesting was basically how teenagers react to light and how we set school schedules. What are your insights on those two potential policy questions?Let's do DST first. This also has horrible UI. Nobody can figure out what they're saying when they talk about DST. So, standard time is brighter mornings, darker evenings. Standard time is what we're on in the winter when everyone's depressed and they're like, "It's 5 p.m. and it's dark. Stupid, stupid DST." That's actually standard time that's causing that. DST is darker mornings, lighter at night. DST is what we're on in the summer when we have lots of light even at 9 p.m. It's really bright at night.The thing most circadian scientists are going to tell you is that permanent standard time is best, then the current system where we switch, and then the last and least preferable is permanent DST. You might think, okay, but why isn't it just better to not switch? There's this penalty of everyone jet lagging themselves when we wake up an hour earlier or have to stay up an hour later when we do these transitions in the spring and the fall. The reason is because having the light late into the day in the summer, and especially having light in the afternoons and evenings in the winter and really, really dark mornings in the winter, is worse than the jet lag from transitioning. If we did permanent DST, where we have really dark mornings in the winter, it wouldn't just be a couple days of us all feeling jet lagged. It would be this chronic buildup of a messed up groove.One of the reasons why it's hard for people to concisely say why permanent DST is bad is because it's about rhythmic health. It's been argued, hey, if you want to maximize the amount of hours that we have really bright light during the daytime periods where people are normally awake, DST is really good for that, because you have light until super late. Think about the summer.But do we want to maximize that?Exactly, because imagine the case that I alluded to when we were talking about the meal timing thing. If you're in bright light 20 hours a day like people are up in the Arctic, you have bad sleep. It's not because you don't know about blackout curtains; it's because you're not able to adjust to a rhythm that's all bright light, little bit of darkness. What permanent DST does is basically, in the wintertime, it forces a bunch of people to wake up in darkness, or dim light. They then stay in the dark for a really long time, and they get their bright light weighted way on the latter half of their day.I'm going to go into a long analogy, but I promise I'll bring it back down. Imagine a sidewalk with alternating yellow and black squares, and I give you a yellow shoe and a black shoe. I say, yellow shoe steps on the yellow square, black shoe steps on the black square. If it's well sized to your legs, you could just do that. You're like, awesome, this is great. But then I do something where I basically take the yellow squares and scoot them up into the black squares. Then I have this brownish, crappy blurring of light and dark: yellow, black, and the blur. If I go, "Okay, walk on this," what you have to do is take one big step with one foot and a little step with your other, and you have to repeat that over and over again.That's basically what DST is doing to you in the winter. If we were to go to that in the winter, you'd wake up in the darkness, but then you'd get light later in the day. It makes it so that your rhythms are thrown off. You wake up with a bunch of melatonin in your body. It's like everybody's popping melatonin pills first thing, if you were to do permanent DST.If you're sitting here thinking, "I'm not convinced by her arguments around stepping on yellow tiles with yellow shoes and black tiles with black shoes," the most compelling reason is the fact that we literally tried this. We tried DST in the winter. We didn't even make a year. Russia tried it in the last decade — they made it three years and they bailed. People have tried DST in the winter and we all think it sucks. Meanwhile, Arizona has been on standard time all year since the 1960s and they're going strong.They seem really thrilled with their situation in Arizona.They're pretty happy. So, moral of the story, the current system would be better than having super dark mornings in the winter, which is what permanent DST would be. But I don't really care that much because I'm so convinced that if we try this again, we'll be like Russia in 2014 and bail. We'll be like us in the '70s and bail. We just need to, as a generation, collectively experience it and realize, oh yeah, this is why DST sucks.The old knowledge has been lost. We must relearn it.We'll relearn it and we'll say, no, we're never going to make this mistake again. And then in 50 years, we'll make it again.People always want the optimization of, I want more sleep. I want eight hours of sleep. I want the most sleep I can possibly get, or I want the most light I can possibly get. It seems like that's a trap. I completely understand why people get into that position, because I like light and I like sleep, but just realistically, if you're seeing how much of this governs the rhythm of lots of different processes that are more sophisticated than just enjoying seeing bright things, it's a real shock to the system.Human brains are just not wired to think rhythmically. It's like if you're in a math class and you're learning about Fourier series, to go extremely niche, really fast. It's not intuitive. People are wired to think, "More of thing good," and we're just less wired to think, well, it's good at some times and bad at other times.Very briefly, then, should kids be going to school as early as they currently go to school?No. At the same time, we also shouldn't make it so late, because what would happen if we made it really late is kids would just stay up later. There are diminishing returns, but now you have kids who are waking up at 5:30. That's absolutely what it would feel like for me to wake up at 3:30. It's cruel to them. There's this idea that, oh, we'll do DST. We'll do permanent DST so we don't have to switch, and then we'll also make school times an hour later.You've basically just got us back to where we started. You've made it so that they're going to be functionally popping a melatonin pill in the morning, just based on how much more melatonin is in their body when they wake up, and then you're letting them sleep in another hour. You cannot make both of those changes and act like you've changed anything. You at best maintain the status quo. My personal vote is we should do permanent standard time or keep the current system and make it so that schools for kids start later.The book is full of really, really interesting studies. Some of them are fascinating, recent, breaking studies that, like you mentioned earlier, reveal incredible things about the link between these biorhythms as well as pharmaceuticals and things like that. Some of them, however, are from a more swashbuckling age of discovery, and you cover a lot of really interesting sleep studies from the earliest days of sleep research. Do you have any favorites?In the book it probably comes across that I am so enamored with these old sleep studies, in part because they really underscore this point that if our definition of sleep health is only duration, it's insufficient. There are a bunch of peer-reviewed papers that went, yeah, this guy said he didn't want to sleep anymore, so he just didn't sleep for a week and we watched him. Actually, that's maybe my favorite. There's this guy who comes into a lab and is like, humans don't need to sleep and I can prove it. And then he just doesn't.They went, whoa, let him cook?Yeah, he might be on to something. In the paper, they're like, we tried to stop him but he said he was going to do it anyway, so we gave him a typewriter to see how bad he got at typing. The answer is, he got so bad at typing so fast that he just went, I can't do this. They didn't make him type anymore because it was too hard for his eyes. He got really snippy. People tend to hallucinate when you keep them up all night. They get paranoid for days and days. But at the same time, he was functioning. He was able to, on the last day of the study, write a vaguely sexist acrostic poem. I have tried to understand this thing. It's confusing, but you get the sense that it's not positive toward women.The original no-sleep creepypasta.Seriously. Obviously, I'm glad we don't do studies like this now. We have human subject protections. Why would you need to run the study? They did that in the '30s and '60s, and it was weird. But the data's been out there for so long. The creepypasta levels of sleep deprivation, people can survive. You should not do it. You should absolutely not do it. It's a bad idea. But it's not an instantly fatal thing, like you pulled an all-nighter so watch out.The punchline is, unfortunately for human brains, which want very rapid feedback and instant gratification, the way to have sleep health is not something acute, like the absence of these all-nighters that are terrible for you, but rather the constant maintenance of healthy rhythms that are on the time scale of weeks, months and years, as opposed to hacks that you can do in one hour of your day.The book is called Sleep Groove: Why Your Body's Clock Is So Messed Up and What To Do About It. There are so many fascinating things in here, Olivia. Why don't you tell readers a little about where they can find the book and you.Sleep Groove is a book about the emerging science of sleep regularity and how it matters so much to your overall health, well-being, and how you feel at 3 a.m. in the morning. You probably feel pretty bad; my book will explain why. You can find it where books are sold, including Amazon and your local independent bookseller. There's also an audiobook coming out next month.Oh, fun. That's great. Thanks so much for coming on, Olivia.Thanks for having me.Edited by Susie Stark.If you have anything you'd like to see in this Sunday special, shoot me an email. Comment below! Thanks for reading, and thanks so much for supporting Numlock.Thank you so much for becoming a paid subscriber! Send links to me on Twitter at @WaltHickey or email me with numbers, tips or feedback at walt@numlock.news. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.numlock.com/subscribe

Fråga Agnes Wold
Agnes Wold om bakterierna i vardagen vi ska akta oss för

Fråga Agnes Wold

Play Episode Listen Later Jan 28, 2025 43:18


Om salmonella, campylobacter och riskerna att smittas av MRSA på gymmet. Lyssna på alla avsnitt i Sveriges Radio Play. Professor Agnes Wold förklarar hur man minskar risken att bli smittad av MRSA, och varför det är så viktigt att torka av maskinerna när man är och tränar. Det handlar också om ehec och legionella, och varför bubbelpooler på badhus kan vara en riskfaktor.Agnes Wold, professor i klinisk bakteriologi, tar sig an samtidens hälsofrågor tillsammans med programledaren Christer Lundberg.Agnes Wold om farliga bakterier:Så smittar MRSA och om att umgås med människor som är bärare av infektionen. Professorn pratar också om salmonella och förklarar var på ägget bakterien finns. Och så diskuterar Agnes och Christer om det finns en risk att smittas av farliga bakterier på offentliga toaletter.Podden som avlivar hälsomyter och ger svar på dina frågor om virus, tarmflora och riskerna med att bädda sängen.

Micro binfie podcast
138 Decoding Tetracycline Resistance in MRSA

Micro binfie podcast

Play Episode Listen Later Jan 16, 2025 11:24


In this episode of the Micro Binfie Podcast, host Andrew Page takes listeners to the heart of the microbial genomics hackathon in Bethesda, Maryland, for an engaging conversation with special guest Megan Phillips, a PhD student from Emory University. Megan delves into her research on Staphylococcus aureus (MRSA), highlighting its fascinating dual nature as both a harmless and potentially serious pathogen. Megan discusses the complexities of tetracycline resistance, particularly focusing on plasmid-mediated mechanisms involving the pt181 plasmid. She explains how this plasmid's efflux pump, encoded by the gene tetK, contributes to variable resistance levels and the factors influencing MIC (Minimum Inhibitory Concentration) variability. Listeners will learn about the intricacies of plasmid copy numbers, their global spread across clonal complexes, and the occurrence of horizontal and vertical gene transfer. Throughout the episode, Megan shares insights on working with short-read sequencing data and the strategies she employs to detect plasmid presence using tools like BLAST. She also touches on the challenges and fascinating discoveries of tracking historical sample data and integrating findings from older research papers, showcasing her appreciation for the poetic style of scientific writing from the 1940s. For those interested in antimicrobial resistance, evolutionary microbiology, and the subtleties of bacterial genome analysis, this episode offers a compelling blend of technical details and engaging storytelling. Tune in to hear more about Megan's upcoming publications, her experiences navigating complex genomic data, and her thoughts on antimicrobial stewardship and historical perspectives on drug resistance.

All That Heals
ep. 20 Kambo Frog Medicine Ceremonies with Ashley Brunette

All That Heals

Play Episode Listen Later Jan 14, 2025 77:59


In this episode Vanessa interviews world renowned Kambo Medicine Ceremony practitioner Ashley Brunette @kambo_ash all about her personal healing journey with deadly MRSA infection, and how Kambo medicine supported her healing journey tremendously and changed her life forever as she became one of the most sought after Kambo practitioners in Ontario, and throughout Canada. They discuss all about Kambo, what it is, its benefits, and Vanessa shares about her two first experiences in her Kambo Ceremonies with Ash and the ripple effects that took place in her life afterwards. Ash's Biography & Intentional Message for Listeners: "As an internationally based physical education teacher and coach for well over a decade, I held several enriching positions in a manner that allowed me to care for the health and well-being of students and team members. After a deadly MRSA infection physically halted my first passion, it propelled me into a yearlong devotion to healing myself from within. Through this journey, Kambo was the catalyst that brought change to the course of my life forever. This metamorphosis has embodied health in all facets, I have gained a deep respect and reverence for the peptide rich Kambo and a variety of therapeutic plant and animal extracts from around the world. I have come to honour and pay heed to my spirit and the path that it leads; allowing this knowledge to feed my soul with rich cultural experiences, training and practice. In March 2020, I travelled deep into the Peruvian jungle to gather and collect medicine from the frog. It was a momentous encounter, one that moved me in many ways. I am so grateful to have had the opportunity to hold this incredible amphibian and give thanks to her for saving my life. The Bufo Alvarius Toad had been calling me since 2017. In the world of sacredelics there are few female practitioners in existence with a safe, comforting environment. I had the opportunity to travel to Mexico in 2020, it was time once again to follow the calls of beyond. The Spirit of the Toad led me to a truly transformative, intensive training, with the top teacher in the world. The training that not only gifted me the ability to serve the “God Molecule,” but to continue to heal myself in profound ways. I understand the need for healing beyond convention: I offer sacred Kambo, Bufo, Hapay (Rapé), Sanaga and Mushroom sessions in safe, comfortable, private settings worldwide. I am a multi-trained professional , with varied experience , that has safely administered amphibian medicine world wide. I have had the opportunity to learn and be taught in the home countries of both amphibians. With deep reverence, I take great responsibility in providing a safe, protected, comfortable, loving, sincere ceremonial space that honours and respects both clients and the medicines. I encourage clients to ask questions to ensure information is clear. RECIPROCITY: The exchange for the medicine reflects a 5% donation to the following communities: Matses and Tahona Odham Tribe Matses - I purchase Kambo from the Matses tribe based in Peru. I have formed a direct alliance with Chief Daniel Manquid Jimenez Huanán and his community. Tahona Odham Tribe - I purchase Bufo from Chief Daniel of the Tahona Odham Tribe based in Santa Ana Sonara, Mexico. The ethical collection and sale of medicine goes back into both communities. Through purchase of medicine and on going donations, the Matses have been able to put in a water filtration system and solar panels in their community. They have also bought tools, clothing, food and school supplies. The Tahona Odaham tribe has been able to provide school supplies, food, clothing and support the women and children in the community with the sale of medicine. I also support the following Indigenous Initiative in Canada: Museum for Dakota Oyate ​​https://oyatemuseum.org/ via Geraldine McManus." This episode was lovingly edited and produced by Joel Corriveau @joelcorriveaux

The Tech Blog Writer Podcast
3136: Tech and Infection Control: Insights from Dr. Deborah Birx and Amy Carenza

The Tech Blog Writer Podcast

Play Episode Listen Later Jan 1, 2025 41:22


How can cutting-edge air decontamination technology reshape healthcare and reduce infections? In today's episode of Tech Talks Daily, we explore this question with Dr. Deborah Birx, Chief Medical & Science Advisor at ActivePure Medical and former White House Coronavirus Response Coordinator, and Amy Carenza, Chief Commercial Officer at ActivePure. Together, they discuss how ActivePure's innovative technology is transforming air and surface purification in healthcare and beyond. ActivePure's advanced photohydrolysis technology, built on principles originally developed by NASA, replicates natural outdoor air purification indoors. Unlike traditional cleaning or filtration methods, this FDA-cleared Class II medical device offers continuous protection in occupied spaces, achieving remarkable results: a 96-99% reduction in MRSA and a 70% decrease in total healthcare-associated infections (HAIs). Dr. Birx and Amy explain how this breakthrough technology deactivates pathogens in real time, effectively filling the gaps left by manual cleaning processes. The conversation delves into the broader implications of ActivePure's solutions, from reducing hospital stays and improving healthcare outcomes to applications in food production, energy-efficient air management, and even residential use. Dr. Birx shares insights from recent studies, including findings published in PLOS ONE and the Journal of Infection Control, which highlight the technology's safety and efficacy. Meanwhile, Amy Carenza discusses how ActivePure is driving innovation to meet operational, quality, and sustainability goals across various industries. As we look to the future, the discussion touches on upcoming advancements in infection prevention, particularly for multi-drug resistant organisms, and the potential for ActivePure's technology to align with efforts to reduce chemical exposures and improve overall public health. How do you see air decontamination technology shaping healthcare and other industries? Join us for this fascinating discussion and share your thoughts!

Breakpoints
#109 – IDWeek 2024 Recap: Practice Changing Papers and ID Potpourri

Breakpoints

Play Episode Listen Later Dec 27, 2024 67:49


We are back with more exciting IDWeek 2024 content. In this episode, Breakpoints hostesses Drs. Erin McCreary, Julie Ann Justo, Jeannette Bouchard, and Megan Klatt highlight more of our favorite sessions and posters at IDWeek, this episode is a must listen if you are an IDWeek nerd like us! References: Perret et al. Application of OpenAI GPT-4 for the retrospective detection of catheter-associated urinary tract infections in a fictitious and curated patient data set. 10.1017/ice.2023.189 Wiemken et al. Assisting the infection preventionist: Use of artificial intelligence for health care–associated infection surveillance. 10.1016/j.ajic.2024.02.007 Leekha et al. Evaluation of hospital-onset bacteraemia and fungaemia in the USA as a potential healthcare quality measure: a cross-sectional study. 10.1136/bmjqs-2023-016831 Diekema et al. Are Contact Precautions "Essential" for the Prevention of Healthcare-associated Methicillin-Resistant Staphylococcus aureus? 10.1093/cid/ciad571 Martin et al. Contact precautions for MRSA and VRE: where are we now? A survey of the Society for Healthcare Epidemiology of America Research Network. 10.1017/ash.2024.350 Browne et al. Investigating the effect of enhanced cleaning and disinfection of shared medical equipment on health-care-associated infections in Australia (CLEEN): a stepped-wedge, cluster randomised, controlled trial. 10.1016/S1473-3099(24)00399-2 Protect trial: Decolonization in Nursing Homes to Prevent Infection and Hospitalization. 10.1056/NEJMoa2215254 Aldardeer et al. Early Versus Late Antipseudomonal β-Lactam Antibiotic Dose Adjustment in Critically Ill Sepsis Patients With Acute Kidney Injury: A Prospective Observational Cohort Study. 10.1093/ofid/ofae059 Schmiemann et al. Effects of a multimodal intervention in primary care to reduce second line antibiotic prescriptions for urinary tract infections in women: parallel, cluster randomised, controlled trial. 10.1136/bmj-2023-076305 Vernacchio et al. Improving Short Course Treatment of Pediatric Infections: A Randomized Quality Improvement Trial. 10.1542/peds.2023-063691 Advani et al. Bacteremia From a Presumed Urinary Source in Hospitalized Adults With Asymptomatic Bacteriuria. 10.1001/jamanetworkopen.2024.2283 Saif et al. Clinical decision support for gastrointestinal panel testing. 10.1017/ash.2024.15 Bekker et al. Twice-Yearly Lenacapavir or Daily F/TAF for HIV Prevention in Cisgender Women. 10.1056/NEJMoa2407001 Montini et al. Short Oral Antibiotic Therapy for Pediatric Febrile Urinary Tract Infections: A Randomized Trial. 10.1542/peds.2023-062598 Nielsen et al. Oral versus intravenous empirical antibiotics in children and adolescents with uncomplicated bone and joint infections: a nationwide, randomised, controlled, non-inferiority trial in Denmark. 10.1016/S2352-4642(24)00133-0 Kaasch et al. Efficacy and safety of an early oral switch in low-risk Staphylococcus aureus bloodstream infection (SABATO): an international, open-label, parallel-group, randomised, controlled, non-inferiority trial. 10.1016/S1473-3099(23)00756-9 AMIKINHAL: Inhaled Amikacin to Prevent Ventilator-Associated Pneumonia. 10.1056/NEJMoa2310307 PROPHY-VAP: Ceftriaxone to prevent early ventilator-associated pneumonia in patients with acute brain injury: a multicentre, randomised, double-blind, placebo-controlled, assessor-masked superiority trial. 10.1016/S2213-2600(23)00471-X AVENIR: Azithromycin to Reduce Mortality — An Adaptive Cluster-Randomized Trial. 10.1056/NEJMoa2312093 Thomas et al. Comparison of Two High-Dose Versus Two Standard-Dose Influenza Vaccines in Adult Allogeneic Hematopoietic Cell Transplant Recipients. 10.1093/cid/ciad458 Schuster et al. The Durability of Antibody Responses of Two Doses of High-Dose Relative to Two Doses of Standard-Dose Inactivated Influenza Vaccine in Pediatric Hematopoietic Cell Transplant Recipients: A Multi-Center Randomized Controlled Trial. 10.1093/cid/ciad534 Mahadeo et al. Tabelecleucel for allogeneic haematopoietic stem-cell or solid organ transplant recipients with Epstein-Barr virus-positive post-transplant lymphoproliferative disease after failure of rituximab or rituximab and chemotherapy (ALLELE): a phase 3, multicentre, open-label trial. 10.1016/S1470-2045(23)00649-6 Khoury et al. Third-party virus-specific T cells for the treatment of double-stranded DNA viral reactivation and posttransplant lymphoproliferative disease after solid organ transplant. 10.1016/j.ajt.2024.04.009 Spec et al. MSG-15: Super-Bioavailability Itraconazole Versus Conventional Itraconazole in the Treatment of Endemic Mycoses—A Multicenter, Open-Label, Randomized Comparative Trial. 10.1093/ofid/ofae010

Integrative Thoughts
Don Moxley | Stemregen : All Natural Plant Compounds that Boost Endogenous Stem Cells

Integrative Thoughts

Play Episode Listen Later Dec 27, 2024 74:44


DON MOXLEY is the Sport Science Director at Stemregen, a leader in stem cell science-backed supplements. Driven by a personal mission to help people make necessary changes to alleviate suffering and enhance the well-being of all, he leverages his experience as an athlete, sports scientist, and educator to advance human performance and longevity. Whether he's sharing insights on a podcast, presenting cutting-edge research on stem cells and performance at a wellness conference, or offering practical advice on living an active and fulfilling life, Don makes the science of stem cells and longevity both accessible and actionable.  A former captain and Big Ten Champion with the Ohio State University wrestling team, he also served as the university's first sport scientist. He helped athletes track their progress in strength, cardiovascular fitness, and resilience training, leading to the team's national title and three Big Ten Championships. Throughout his career, Don has guided athletes to remarkable success, including two Olympic medals, four World Championships, seven National Championships, and 23 All-American honors.   Work With Me: Mineral Balancing HTMA Consultation: https://www.integrativethoughts.com/category/all-products  My Instagram: @integrativematt My Website: Integrativethoughts.com   Advertisements:   Viva Rays: Use Code ITP for a Discount https://vivarays.com/   Zeolite Labs Zeocharge: Use Code ITP for 10% off https://www.zeolitelabs.com/product-page/zeocharge?ref=ITP Magnesium Breakthrough: Use Code integrativethoughts10 for 10% OFF https://bioptimizers.com/shop/products/magnesium-breakthrough Just Thrive: Use Code ITP15 for 15% off https://justthrivehealth.com/discount/ITP15 Therasage: Use Code Coffman10 for 10% off https://www.therasage.com/discount/COFFMAN10?rfsn=6763480.4aed7f&utm_source=refersion&utm_medium=affiliate&utm_campaign=6763480.4aed7f   Chapters: 00:00 Introduction to Don Moxley and StemRgen 05:53 The Role of Stem Cells in Recovery 15:02 The Importance of Staying Active 20:20 The Science Behind Stem Regen 28:37 Exogenous Stem Cells vs. Natural Supplements 35:21 The Power of Hyperbaric Therapy 40:37 The Importance of Longevity and Vitality 49:18 Exploring Stem Cells and Their Applications 56:01 The Importance of Micronutrients 01:01:19 Personalized Health and Optimization   Takeaways: HRV is a crucial indicator of recovery and performance. Stem cells play a vital role in the body's healing process. Aging leads to a decline in stem cell production. Staying active is essential for longevity and health. Stem Regen can enhance the body's natural healing abilities. Exercise stimulates the release of beneficial molecules like BDNF. Natural supplements can be more accessible than exogenous stem cell treatments. Maintaining a healthy lifestyle can improve overall well-being. The body responds better to gradual increases in stem cell circulation. It's important to be cautious with supplements and their certifications. Hyperbaric therapy can provide significant relief from chronic pain. STEM Regen protocol led to a rapid recovery from knee pain. Inflammation is a major barrier to healing and performance. Longevity is about feeling good and being active at any age. Hormone replacement therapy can be a natural part of health optimization. Nutrition quality is often compromised in industrial food production. Personalized health strategies are essential for optimal performance. Micronutrients play a critical role in cellular health and recovery. Understanding your body's needs is key to thriving as you age. Supplementation can help address deficiencies in modern diets.   Summary: In this conversation, Matthew Coffman interviews Don Moxley, an expert in exercise physiology and stem cell research. They discuss the importance of heart rate variability (HRV) as a key performance indicator for health and recovery, the role of stem cells in healing and recovery, and how aging affects stem cell production. Moxley shares insights on the benefits of staying active and the significance of supplements like StemRgen in enhancing recovery and performance. The discussion also touches on the differences between exogenous stem cells and natural supplements, emphasizing the importance of a holistic approach to health and wellness. In this conversation, Don Moxley shares his personal journey of overcoming significant health challenges, including a serious knee injury and subsequent MRSA infection. He discusses the transformative effects of hyperbaric therapy and the STEM Regen protocol, which helped him regain mobility and reduce inflammation. The conversation also delves into the importance of longevity, hormone replacement therapy, and the role of nutrition in optimizing health and performance. Moxley emphasizes the need for personalized health strategies and the significance of micronutrients in achieving overall well-being.  

True Healing with Robert Morse ND
Dr. Morse Q&A - MRSA - Fibroids - Atrial Fibrillation - Raynaud's Syndrome - Hormones #745

True Healing with Robert Morse ND

Play Episode Listen Later Dec 20, 2024 84:26


To have your question featured in a future video, please email: questions@drmdc.health

The ASHE Podcast
Episode 17: Rethinking Contact Precautions: A Genomic Lens on MRSA in Acute Care

The ASHE Podcast

Play Episode Listen Later Dec 12, 2024 35:13


In this episode of The ASHE Podcast, we explore how innovative approaches in infection prevention are reshaping healthcare practices. Guests Graham Snyder, Elise Martin, and Ashley Ayers join the discussion to discuss their study titled "Impact of Discontinuation of Contact Precautions on Surveillance- and Whole Genome Sequencing-Defined Methicillin-Resistant Staphylococcus aureus Healthcare-Associated Infections" and what it means for the future of infection control. The conversation explores the evolving role of contact precautions (CP) in managing MRSA transmission. The discontinuation of CP has sparked debates in infection prevention, with this study providing a fresh perspective through whole genome sequencing (WGS). Unlike traditional surveillance methods, WGS offers deeper insights into MRSA transmission dynamics, unveiling patterns that can redefine how we approach infection control in acute care settings. The study's findings revealed a surprising drop in MRSA healthcare-associated infections (HAIs) post-discontinuation of CP, raising questions about how to balance infection prevention with resource management and patient safety. By reducing reliance on CP, hospitals may gain advantages such as cost savings and fewer adverse effects for patients, without compromising care quality. Finally, the episode delves into challenges faced during the study and the need for further research to refine infection prevention strategies. Future efforts could focus on tailoring CP to specific risks and developing more precise methods for tracking and preventing MRSA transmission. Be sure to read the full article available at Cambridge.org/ASHE. And for the official SHEA recommendations for MRSA treatment and prevention visit: https://www.cambridge.org/core/journals/infection-control-and-hospital-epidemiology/article/sheaidsaapic-practice-recommendation-strategies-to-prevent-methicillinresistant-staphylococcus-aureus-transmission-and-infection-in-acutecare-hospitals-2022-update/5DB835D2E13F7E813A8A2FD7CB8386BD

Solder and Soot: A NARSA/IDEA Podcast
Joe & Anthony DePonio

Solder and Soot: A NARSA/IDEA Podcast

Play Episode Listen Later Dec 10, 2024 44:38


Did you know NARSA was originally known as MRSA? In the latest episode of Solder & Soot, Joe and Anthony DePonio lead us into a deep dive of NARSA's 70-year history starting with NARSA's first President Dominick DePonio. Plus, we learn more about Joe and Anthony's careers in cooling systems from Heatex to LKQ. This episode is sponsored by Johnson Manufacturing.

Micro binfie podcast
134 Diving into MRSA, Genomics, and Public Health

Micro binfie podcast

Play Episode Listen Later Dec 5, 2024 13:27


In this episode of the Micro Binfie Podcast, host Andrew Page speaks with Dr. Brooke Talbot, a recent PhD graduate from Emory University, about her research on Staphylococcus aureus, with a focus on MRSA and antibiotic resistance. Brooke shares insights into her molecular epidemiology work, discussing the complexities of tracking resistant bacterial strains in clinical settings and the significance of genomic epidemiology in public health. From honeybees to foodborne outbreaks, Brooke's diverse research background offers listeners a fascinating journey through science, microbiology, and epidemiology.

DailyQuarks – Dein täglicher Wissenspodcast
SPEZIAL: Antibiotika - Lebensretter mit Nebenwirkungen

DailyQuarks – Dein täglicher Wissenspodcast

Play Episode Listen Later Nov 29, 2024 29:56


Für manche sind Antibiotika Lebensretter, aber sogar Ärzte und Ärztinnen warnen vor den Nebenwirkungen und Resistenzen. Wie gut sind Antibiotika wirklich? // Alle Quellen und weitere Spezials findest Du hier: https://www.quarks.de/daily-quarks-spezial // Hast Du Feedback, dann melde Dich über WhatsApp oder Signal unter 0162 344 86 48 Von Christina Sartori.

USF Health’s IDPodcasts
HIV Dermatology

USF Health’s IDPodcasts

Play Episode Listen Later Nov 29, 2024 51:35


Dr. Patrick Danaher, Infectious Diseases Clinician at the USF Morsani College of Medicine, discusses the various dermatologic manifestations of HIV in this recorded session. Among the topics discussed includes genital herpes disease, Zoster, Mpox infections, MRSA skin lesions, and Kaposi sarcoma. The lecture is presented in a case-based format.

This Week in Microbiology
322: Photohydrolysis Decontamination Reduces Healthcare-associated Infections

This Week in Microbiology

Play Episode Listen Later Nov 22, 2024 58:12


TWiM explains how ticagrelor alters the membrane of S. aureus and enhances the activity of vancomycin and daptomycin without eliciting cross-resistance, and the development of a novel continuous disinfectant technology that decreases healthcare-associated infections in ICUs by 70%. Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson. Become a patron of TWiM. Links for this episode Ticagrelor and S. aureus (mBio) Novel disinfectant technology (Am J Inf Control) UVC-LED to inactivate foodborne pathogens (Appl Envir Micro) UV disinfection systems (ACS Photonics) High-touch surfaces in specialized patient care area (CDC) Take the TWiM Listener survey! Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv  

Pharmacist Diaries
164 Vanessa Carter: The Antimicrobial Stewardship Series: Protecting Tomorrow's Medicine (Episode 2)

Pharmacist Diaries

Play Episode Listen Later Nov 19, 2024 32:09


In this powerful World Antimicrobial Resistance Awareness Week (WAAW) special episode, we hear from Vanessa Carter, a remarkable Antimicrobial Resistance (AMR) survivor turned global health advocate. After a devastating car accident in 2004 led to multiple facial reconstruction surgeries, Vanessa developed a drug-resistant MRSA infection that changed her life's trajectory. Her journey from patient to Chair of the WHO Task Force of AMR Survivors highlights the critical importance of patient education and antimicrobial stewardship. Vanessa shares crucial insights about the gaps in patient communication, the need for better infection prevention education, and the importance of tracking antibiotic usage. Key Takeaway Messages: For Healthcare Professionals: Simple, clear communication about infection risks can save lives Consider patient literacy levels when explaining complex concepts Integrate infection prevention education throughout the patient journey Collaborate across specialties for better patient outcomes For Patients: Ask questions about infection prevention and control Keep records of antibiotic treatments when possible Watch for signs of recurring infections Don't hesitate to seek help if infections don't improve For Policy Makers: Include patient voices in healthcare system design Invest in better diagnostic tools Develop integrated antibiotic tracking systems Support early education initiatives about AMR HAVE YOU EVER THOUGHT ABOUT LIFE OUTSIDE THE TRADITIONAL 9-5? Are you a pharmacist dreaming of: - Working on your own terms? - Achieving location independence? - Building financial freedom? I've been there. That's why I'm sharing my journey from traditional 9-5 pharmacist to creating a life of freedom and fulfillment. In this weekly newsletter, I'll be opening up about my transition to unconventional pharmacy, practical tips for working on your own terms, strategies for financial independence, and our family's adventures in homeschooling and world travel. Ready to reimagine what's possible in your pharmacy career and life? Sign up

Emergency Medical Minute
Episode 928: Neutropenic Fever

Emergency Medical Minute

Play Episode Listen Later Oct 28, 2024 5:54


Contributor: Taylor Lynch, MD Educational Pearls: What is neutropenic fever? Specific type of fever that is seen in cancer patients and other patients with impaired immune systems These patients are highly susceptible to infection Typically occurs 7-10 days after the last chemotherapy dose, this is when the immune system is the weakest It is useful to know the specific type of malignancy. For example, heme malignancies (ALL, AML, etc.) have more intense chemo and are at higher risk of neutropenic fever To qualify as a neutropenic fever, a patient must have one recorded temperature greater than 38.3 degrees C or be over 38 degrees C for one hour. The severity of the neutropenic fever is established by the absolute neutrophil count. Abs neutrophil count under 1500 is mild, less than 1000 is moderate, less than 500 is severe. Also look at monocytes (cell that becomes a macrophage). Less than 200 is very concerning What is the workup and treatment? Obtain a panculture (culture blood from both arms and all indwelling lines), obtain urine culture, and get a chest x-ray. Do not preform a rectal exam or obtain a rectal core temperature. This could cause bacteremia. Treat with Cefepime (broad range and includes pseudomonas but not MRSA). If there is concern for MRSA add vancomycin. Admit with Neutropenic precautions (gowns, gloves, mask, positive pressure room) References Peseski, A. M., McClean, M., Green, S. D., Beeler, C., & Konig, H. (2021). Management of fever and neutropenia in the adult patient with acute myeloid leukemia. Expert review of anti-infective therapy, 19(3), 359–378. https://doi.org/10.1080/14787210.2020.1820863 Zimmer, A. J., & Freifeld, A. G. (2019). Optimal Management of Neutropenic Fever in Patients With Cancer. Journal of oncology practice, 15(1), 19–24. https://doi.org/10.1200/JOP.18.00269 Summarized by Jeffrey Olson, MS3 | Edited by Meg Joyce & Jorge Chalit, OMS3  

Breakpoints
#105 – Bringing Positive Vibes Only: Breaking News & Emerging Hypotheses for Gram-Positive Bacterial Infections

Breakpoints

Play Episode Listen Later Oct 25, 2024 73:06


Drs. Cesar Arias (@SuperBugDoc) and Katie Barber join Dr. Julie Ann Justo (@julie_justo) to discuss what is hot-off-the-presses for gram-positive bacterial infections and it's a total party vibe! They review the latest news for recent and ongoing clinical trials (DOTS, DISRUPT, and SNAP trials), discuss hope for novel clinical tests of the cefazolin inoculum effect in staphylococci, and explore the fascinating changes in virulence and potential therapeutic options for the most challenging enterococci. Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About X: @SIDPharm (https://twitter.com/SIDPharm) Instagram: @SIDPharm (https://www.instagram.com/sidpharm/) Facebook: https://www.facebook.com/sidprx LinkedIn: https://www.linkedin.com/company/sidp References Climate Change and Antimicrobial Resistance. Editors in Conversation Podcast. American Society for Microbiology. Oct 2023. Is More Better? The Role of Combination Therapy for MRSA. Breakpoints Podcast Episode #30. Society of Infectious Diseases Pharmacists. Turner NA, et al. DOTS: Dalbavancin as an Option for Treatment of Staphylococcus aureus Bacteremia. ESCMID Global 2024. April 2024. NCT04775953. Real-world dalbavancin observational cohort: Rebold N, et al. Infect Dis Ther. 2024 Mar;13(3):565-579. doi: 10.1007/s40121-024-00933-2. PMID: 38427289. Exebacase DISRUPT trial : Fowler VG Jr, et al. Clin Infect Dis. 2024 Jun 14;78(6):1473-1481. doi: 10.1093/cid/ciae043. PMID: 38297916. @snap_trial tweet of Breaking News. Aug 2024. Investigator Resources for the SNAP trial. Sept 2024: https://www.snaptrial.com.au/for-investigators#interim Cefazolin inoculum effect on mortality in MSSA bacteremia : Miller WR, et al. Open Forum Infect Dis. 2018 May 23;5(6):ofy123. doi: 10.1093/ofid/ofy123. PMID: 29977970. Prevalence of cefazolin inoculum effect in MSSA and modified rapid nitrocefin test for detection: Carvajal LP, et al. Antimicrob Agents Chemother. 2024 Sep 30:e0089824. doi: 10.1128/aac.00898-24. PMID: 39345182. LiaX as surrogate for cell envelope stress in Enterococus faecium: Axell-House DB, et al. Antimicrob Agents Chemother. 2024 Mar 6;68(3):e0106923. doi: 10.1128/aac.01069-23. PMID: 38289081. Shorter is better for uncomplicated streptococcal bacteremia: Clutter DS, et al. Antimicrob Agents Chemother. 2024 Aug 7;68(8):e0022024. doi: 10.1128/aac.00220-24. PMID: 38975753. Short vs. long antibiotic duration in Streptococcus pneumoniae bacteremia: Crotty M, et al. Open Forum Infect Dis. 2024 Aug 30;11(9):ofae478. doi: 10.1093/ofid/ofae478. PMID: 39257675. This podcast is powered by Pinecast.

Memorizing Pharmacology Podcast: Prefixes, Suffixes, and Side Effects for Pharmacy and Nursing Pharmacology by Body System
Ep 147 OER 3.20 Miscellaneous Antibacterials Glycopeptides - Nursing Pharmacology

Memorizing Pharmacology Podcast: Prefixes, Suffixes, and Side Effects for Pharmacy and Nursing Pharmacology by Body System

Play Episode Listen Later Oct 7, 2024 3:36


Free book is here at https://www.memorizingpharm.com/books Summary 3.20 Vancomycin  The chapter covers vancomycin, a glycopeptide antibiotic used for treating serious infections like MRSA. It works by inhibiting bacterial cell wall synthesis. Vancomycin is typically administered via IV for systemic infections and orally for C-diff. Key concerns include nephrotoxicity, ototoxicity, and "red man syndrome," which occurs with rapid infusion. Monitoring of renal function and trough levels is crucial. Multiple Choice Questions What is vancomycin primarily used to treat? a) Viral infections b) MRSA c) Fungal infections d) Diabetes How does vancomycin work? a) Disrupts protein synthesis b) Inhibits cell wall synthesis c) Increases glucose uptake d) Enhances DNA replication What condition can occur if vancomycin is infused too quickly? a) Hair loss b) Red man syndrome c) Weight gain d) Increased appetite How is vancomycin administered for systemic infections? a) Orally b) Topically c) Intravenously d) Subcutaneously Which function should be closely monitored during vancomycin therapy? a) Cardiac function b) Renal function c) Respiratory function d) Blood glucose levels Answer Key b) MRSA b) Inhibits cell wall synthesis b) Red man syndrome c) Intravenously b) Renal function

The Studies Show
Episode 51: Antimicrobial resistance

The Studies Show

Play Episode Listen Later Oct 1, 2024 50:16


There are an awful lot of things to worry about in the world. Are “superbugs” among them? That is, how worried should we be that bacteria will develop resistance to our best antibiotics, meaning infections will run rampant and even basic surgery is out of the question?In this episode of The Studies Show, Tom and Stuart wash their hands and then dig in to the evidence on the coming antimicrobial crisis. Exactly how many deaths can we expect from untreatable resistant infections? Turns out the question is, ahem, resistant to easy answers. (Sorry).The Studies Show is brought to you by Works in Progress magazine. Every issue, every article, gives you a new perspective on a topic you thought you knew about, or a totally new topic to think about. In their most recent issue, you can read about inflation, ancient scrolls and AI, genetic engineering, and the evolution of coffee. We're grateful that they support the podcast; you can read their whole site for free at worksinprogress.co.Show notes* Andreas Bäumler on “the coming microbial crisis”* Possible source for how many people used to die in surgery * BMJ article on the evidence (or lack of) showing that completing an antibiotic course is necessary* Satirical post on how the length of a course is calculated* Our World In Data on how many people die from cancer each year* UK Government review of antimicrobial resistance (from 2014), giving the 10m figure. * More mentions of 10m here (NHS), and here (Guardian)* 2016 paper in PLOS Medicine criticising the modelling that led to the 10m figure* September 2024 paper in the Lancet with a more up-to-date calculation* EU report on how MRSA rates dropped* Article on the wildly successful UK attempt to cut MRSA infections* Study on how many antibiotics are in the clinical “pipeline”* Thread on studies showing that using antibiotics prophylactically cut child mortality in sub-Sarahan Africa by 14%Credits* The Studies Show is produced by Julian Mayers at Yada Yada Productions. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.thestudiesshowpod.com/subscribe

Coffee and a Mike
Mimi Morgan #936

Coffee and a Mike

Play Episode Listen Later Sep 27, 2024 94:37


Mimi Morgan has overcome rheumatoid arthritis, Parkinson's disease, stroke, and spinal MRSA. She talks the conversations that changed her life, going from keto to carnivore, being in the best shape of her life at 70 years old and much more. PLEASE SUBSCRIBE LIKE AND SHARE THIS PODCAST!!!   Video Version of Show Rumble- https://rumble.com/v5gimvp-coffee-and-a-mike-mimi-morgan-the-longest-route-was-the-shortest.html   Follow Me Twitter/X- https://twitter.com/CoffeeandaMike Instagram- https://www.instagram.com/coffeeandamike/ Facebook- https://www.facebook.com/CoffeeandaMike/ Truth Social- https://truthsocial.com/@coffeeandamike Gettr- https://gettr.com/user/coffeeandamike Rumble- https://rumble.com/search/all?q=coffee%20and%20a%20mike Apple Podcasts- https://podcasts.apple.com/us/podcast/coffee-and-a-mike/id1436799008 Gab- https://gab.com/CoffeeandaMike Locals- https://coffeeandamike.locals.com/ Website- www.coffeeandamike.com Email- info@coffeeandamike.com   Support My Work Venmo- https://www.venmo.com/u/coffeeandamike Patreon- patreon.com/coffeeandamike Locals- https://coffeeandamike.locals.com/ Cash App- https://cash.app/$coffeeandamike Mail Check or Money Order- Coffee and a Mike LLC P.O. Box 25383 Scottsdale, AZ 85255-9998   Follow Mimi Twitter/X- https://x.com/mimikmorgan Instagram- https://www.instagram.com/mimimorgank/            

Memorizing Pharmacology Podcast: Prefixes, Suffixes, and Side Effects for Pharmacy and Nursing Pharmacology by Body System

Free book is here at https://www.memorizingpharm.com/books In this episode we return to turning the open educational nursing resource for nursing pharmacology into audio, we'll start with the 1st edition antimicrobials then move on to the new second edition with the next topic.  Summary 3.6 Cephalosporins Nursing Pharmacology  Chapter 3.6 of the Nursing Pharmacology guide focuses on cephalosporins, a class of antibiotics similar to penicillins. The chapter covers their mechanism (cell wall disruption), indications (skin, bone, respiratory infections), different generations with expanding spectra, and administration considerations. It also highlights monitoring for allergies, renal impairment, and possible disulfiram-like reactions with alcohol. Patient education emphasizes avoiding alcohol and reporting signs of superinfection. Multiple Choice Questions Cephalosporins work primarily by: a) Inhibiting protein synthesis b) Disrupting cell wall synthesis c) Altering DNA replication d) Blocking RNA transcription Which generation of cephalosporins is effective against MRSA? a) 1st generation b) 2nd generation c) 4th generation d) 5th generation What side effect may occur when consuming alcohol with cephalosporins? a) Increased appetite b) Hair loss c) Disulfiram-like reaction d) Drowsiness Patients with allergies to penicillin might also react to: a) Cephalosporins b) Tetracyclines c) Aminoglycosides d) Fluoroquinolones What should be monitored when administering cephalosporins to a patient with renal impairment? a) Blood pressure b) Liver enzymes c) Blood urea nitrogen (BUN) and creatinine d) Heart rate Answer Key b) Disrupting cell wall synthesis d) 5th generation c) Disulfiram-like reaction a) Cephalosporins c) Blood urea nitrogen (BUN) and creatinine ```

Think Out Loud
OSU researchers awarded $2 million to study antibiotic-resistant bacteria in wastewater

Think Out Loud

Play Episode Listen Later Sep 12, 2024 16:02


Each year, there are nearly three million cases of antibiotic-resistant infections in the U.S. caused by MRSA and other antibiotic-resistant bacteria, according to the Centers for Disease Control and Prevention. While many of these infections happen during hospital stays, less is known about the role wastewater treatment facilities can play in the spread of antibiotic-resistant bacteria in the environment. Researchers at Oregon State University aim to change that with a new study that launched this month. They were awarded more than $2 million from the Environmental Protection Agency to study the presence of antibiotics, antibiotic-resistant bacteria and their genes at 40 wastewater treatment facilities in the U.S., including Oregon. The two-year-long study will also look at seasonal and regional differences in the population of that bacteria and how different treatment processes affect their growth and evolution. Joining us to share details of the study is Tala Navab-Daneshmand, the principal investigator of the study and an associate professor of engineering at OSU.   

One World, One Health
“My life is never going to be normal again.” – The toll of antibiotic resistance

One World, One Health

Play Episode Listen Later Sep 10, 2024 14:24


Rosemary Bartel had no idea her life was going to take a turn when she went to a hospital near her home in Chilton, Wisconsin in the United States for standard knee replacement surgery – her second such operation. She was ready to work hard to recover and return to her busy job at her Roman Catholic diocese. But Rosie developed an all-too-common infection known as MRSA—methicillin-resistant Staphylococcus aureus. It's one of the best-known examples of antimicrobial-resistant microbes, often called superbugs. The United Nations is devoting a high-level meeting to the problem in September 2024 in the hopes of getting nations to do more to fight antimicrobial resistance or AMR.Now, 15 years later, Rosie has had her leg and hip amputated because the infection got into her bones. She has suffered numerous other infections, been in comas, lost her job, lost her health insurance, and lost most of the life she had loved.“I will probably be paying hospital bills for the rest of my life,” Rosie tells One World, One Health. Rosie is one of the luckier victims of AMR. She's still alive. Five million people a year die from complications caused by these drug-resistant germs. Now, Rosie shares her story as widely as she can as part of the Patient Family Partners Network, a group of patient advocates working to improve healthcare in the United States, and the Leapfrog Group, a nonprofit patient safety advocacy organization. She's also written a book, “Rosie's Story,” about her experience with this devastating and unending infection. Listen as Rosie describes what happened to her and what she hopes to do to help stop it from happening to others

Shed Heads
Episode 50: Hello Football!

Shed Heads

Play Episode Listen Later Sep 6, 2024 106:51


The boys are back in the shed this week for the NFL kickoff!  We talk about college football, how much FSU and Clemson suck, Legionnaire's disease, MRSA, and other tough injuries, with our special guest Helen Cover.  

PVRoundup Podcast
Brain-computer interface enables man with ALS to speak again

PVRoundup Podcast

Play Episode Listen Later Aug 20, 2024 4:55


Can artificial intelligence restore speech in patients with ALS? Find out about this and more in today's PeerDirect Medical News Podcast.

The ICHE Podcast
Episode 51: Understanding S. aureus and MRSA: Transmission, Risks, and Control Strategies

The ICHE Podcast

Play Episode Listen Later Aug 9, 2024 34:10


In this episode of the ICHE Podcast, we delve into the topic of Staphylococcus aureus (S. aureus) and Methicillin-resistant Staphylococcus aureus (MRSA), focusing on healthcare-associated infections and transmission. Our expert panel of authors from recently published ICHE papers includes Anthony Harris, MD, MPH, Elise Martin, MD, MS, and Philip M. Polgreen, MD, MPH. Listen as they discuss the prevalence of these infections, the risks they pose, and the strategies that can be employed to reduce transmission in both healthcare settings and households. At the conclusion of today's episode, each participant offers a practical, actionable recommendation for listeners.

PlanBri Uncut
We Have MRSA Brain | PlanBri Uncut Episode 278

PlanBri Uncut

Play Episode Listen Later Aug 8, 2024 60:17


Brianna Lapaglia and Grace O'Malley are being wicked weird and creepy on today's episode. Grace recaps her sold out comedy show while Brianna shares her night out in Philly. Spoiler alert: Brianna has MRSA brain and Grace is dreaming throughout this entire episode! Enjoy! 00:00 Grace's Cough 1:40 Grace's Comedy Show 4:05 Brianna's time to Philly 10:40 Flash Flood Warning 12:55 Grace's Mom is a Heckler 18:05 Billy Joel 21:30 Cousin Seano Gimme My Money 23:00 Instigators Premiere Recap 29:35 Brianna has MRSA 33:00 Yucky Stuff 38:30 SPOILER ALERT 40:00 Brianna's WIFI Guy 43:25 Smokeshows 45:00 MRSA Brain Conversation ---------- SUPPORT THE SHOW: Go to drinkpiratewater.com to find Pirate Water in a location near you! Download the Gametime app or go to https://gametime.co, enter your email, and redeem code PLANBRI for $20 off your first purchase (terms apply). Use code BRI15 on https://HustleButter.com for 15% off your order. Head to Sunglass Hut and discover the special selection of shades in store and online at https://sunglasshut.com.You can find every episode of this show on Apple Podcasts, Spotify or YouTube. Prime Members can listen ad-free on Amazon Music. For more, visit barstool.link/planbri

Rio Bravo qWeek
Episode 173: Acute Osteomyelitis

Rio Bravo qWeek

Play Episode Listen Later Jul 5, 2024 17:42


Episode 173: Acute OsteomyelitisFuture Dr. Tran explains the pathophysiology of osteomyelitis and describes the presentation, diagnosis and management of acute osteomyelitis. Dr. Arreaza provides information about    Written by Di Tran, MSIII, Ross University School of Medicine. Editing and comments by Hector Arreaza, MD.You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice.What is osteomyelitis?Osteomyelitis, in simple terms, is an infectious disease that affects both bone and bone marrow and is either acute or chronic.  According to archaeological findings of animal fossils with a bone infection, osteomyelitis was more than likely to be known as a “disease for old individuals”.Our ancestors over the years have used various vocabulary terms to describe this disease until a French surgeon, Dr. Nelaton, came up with the term “Osteomyelitis” in 1844. This is the beauty of medical terms, Latin sounds complicated for some people, but if you break up the term, it makes sense: Osteo = bone, myelo = marrow, itis = inflammation. So, inflammation of the bone marrow.Traditionally, osteomyelitis develops from 3 different sources:First category is the “hematOgenous” spread of the infection within the bloodstream, as in bacteremia. It is more frequent in children and long bones are usually affected. [Arreaza: it means that the infection started somewhere else but it got “planted” in the bones]Second route is “direct inoculation” of bacteria from the contiguous site of infection “without vascular insufficiency”, or trauma, which may occur secondary to fractures or surgery in adults.  In elderly patients, the infection may be related to decubitus ulcers and joint replacements.And the third route is the “contiguous” infection “with vascular insufficiency”, most seen in a patient with a diabetic foot infection.Patients with vascular insufficiency often have compromised blood supply to the lower extremities, and poor circulation impairs healing. In these situations, infection often occurs in small bones of the feet with minimal to no pain due to neuropathy.They can have ulcers, as well as paronychia, cellulitis, or puncture wounds.Thus, the importance of treating onychomycosis in diabetes because the fungus does not cause a lot of problems by itself, but it can cause breaks in the nails that can be a port of entry for bacteria to cause severe infections. Neuropathy is an important risk factor because of the loss of protective sensation. Frequently, patients may step on a foreign object and not feel it until there is swelling, purulent discharge, and redness, and they come to you because it “does not look good.”Acute osteomyelitis often takes place within 2 weeks of onset of the disease, and the main histopathological findings are microorganisms, congested blood vessels, and polymorphonuclear leukocytes, or neutrophilic infiltrates.What are the bugs that cause osteomyelitis?Pathogens in osteomyelitis are heavily depended on the patient's age.  Staph. aureus is the most common culprit of acute hematogenous osteomyelitis in children and adults.  Then comes Group A Strep., Strep. pneumoniae, Pseudomonas, Kingella, and methicillin-resistant Staph. aureus.  In newborns, we have Group B Streptococcal. Less common pathogens are associated with certain clinical presentations, including Aspergillus, Mycobacterium tuberculosis, and Candida in the immunocompromised.Salmonella species can be found in patients with sickle cell disease, Bartonella species in patients with HIV infection, and Pasteurella or Eikenella species from human or animal bites.It is important to gather a complete medical history of the patient, such as disorders that may put them at risk of osteomyelitis, such as diabetes, malnutrition, smoking, peripheral or coronary artery disease, immune deficiencies, IV drug use, prosthetic joints, cancer, and even sickle cell anemia. Those pieces of information can guide your assessment and plan.What is the presentation of osteomyelitis?Acute osteomyelitis may present symptoms over a few days from onset of infection but usually is within a 2-week window period.  Adults will develop local symptoms of erythema, swelling, warmth, and dull pain at the site of infection with or without systemic symptoms of fever or chills.Children will also be present with lethargy or irritability in addition to the symptoms already mentioned.It may be challenging to diagnose osteomyelitis at the early stages of infection, but you must have a high level of suspicion in patients with high risks. A thorough physical examination sometimes will show other significant findings of soft tissue infection, bony tenderness, joint effusion, decreased ROM, and even exposed bone. Diagnosis.As a rule of thumb, the gold standard for the diagnosis of osteomyelitis is bone biopsy with histopathology findings and tissue culture. There is leukocytosis, but then WBC counts can be normal even in the setting of acute osteomyelitis.Inflammatory markers (CRP, ESR) are often elevated although both have very low specificity. Blood cultures should always be obtained whenever osteomyelitis is suspected.  A bone biopsy should also be performed for definitive diagnosis, and specimens should undergo both aerobic and anaerobic cultures.  In cases of osteomyelitis from diabetic foot infection, do the “probe to bone” test. What we do is we use a sterile steel probe to detect bone which is helpful for osteomyelitis confirmation.Something that we can't miss out on is radiographic imaging, which is quite important for the evaluation of osteomyelitis.  Several modalities are useful and can be used for the work-up plan; plain radiographs often are the very first step in the assessment due to their feasibility, low cost, and safety.  Others are bone scintigraphy, CT-scan, and MRI.  In fact, the MRI is widely used and provides better information for early detection of osteomyelitis than other imaging modalities.  It can detect necrotic bone, sinus tracts, and even abscesses. We look for soft tissue swelling, cortical bone loss, active bone resorption and remodeling, and periosteal reaction.  Oftentimes, plain radiography and MRI are used in combination. Treatment:Treatment of osteomyelitis actually is a teamwork effort among various medical professionals, including the primary care provider, the radiologist, the vascular, the pharmacist, the podiatrist, an infectious disease specialist, orthopedic surgeons, and the wound care team.Something to take into consideration, if the patient is hemodynamically stable it is highly recommended to delay empirical antibiotic treatment 48-72 hours until a bone biopsy is obtained.  The reason is that with percutaneous biopsy ideally done before the initiation of antibiotic treatment, “the microbiological yield will be higher”.We'll have a better idea of what particular bugs are causing the problem and guide the treatment appropriately. The choice of antibiotic therapy is strongly determined by susceptibilities results.  The antibiotic given will be narrowed down only for the targeted susceptible organisms.  In the absence of such information, or when a hospitalized patient presents with an increased risk for MRSA infection, empiric antibiotic coverage is then administered while awaiting culture results. It should be broad-spectrum antibiotics and include coverage for MRSA, broad gram-negative and anaerobic bacteria.  For example, vancomycin plus piperacillin-tazobactam, or with broad-spectrum cephalosporin plus clindamycin.  Treatment will typically be given for 4 to 6 weeks.The duration between 4-6 weeks is important for complete healing, but a small study with a small sample showed that an even shorter duration of 3 weeks may be effective, but more research is needed. In certain situations, surgery is necessary to preserve viable tissue and prevent recurrent infection, especially when there are deep abscesses, necrosis, or gangrene, amputation or debridement is deemed appropriate. If the infected bone is completely removed, patients may need a shorter course of antibiotics, even a few days only. Amputation can be very distressing, especially when we need to remove large pieces of infected bone, for example, a below-the-knee amputation. We need to be sensitive to the patient's feelings and make a shared decision about the best treatment for them.In patients with diabetes, additional care must be taken seriously, patient education about the need for compliance with treatment recommendations, with careful wound care, and good glycemic control are all beneficial for the healing and recovery process. Because this is a very common problem in the clinic and at the hospital, we must keep our eyes wide open and carefully assess patients with suspected osteomyelitis to detect it promptly and start appropriate treatment. Adequate and timely treatment is linked to fewer complications and better outcomes._________________________Conclusion: Now we conclude episode number 173, “Acute Osteomyelitis.” Future Dr. Tran explained the pathophysiology, diagnosis, and management of osteomyelitis. A bone biopsy is the ideal method of diagnosis. Delaying antibiotic treatment a few days until you get a biopsy is allowed if the patient is stable, but if the patient is unstable, antibiotics must be started promptly. Dr. Arreaza mentioned the implications of amputation and that we must discuss this treatment empathically with our patients. This week we thank Hector Arreaza and Di Tran. Audio editing by Adrianne Silva.Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! _____________________References:Bury DC, Rogers TS, Dickman MM. Osteomyelitis: Diagnosis and Treatment. Am Fam Physician. 2021 Oct 1;104(4):395-402. PMID: 34652112.Cunha BA. Osteomyelitis in elderly patients. Clin Infect Dis. 2002 Aug 1;35(3):287-93. doi: 10.1086/341417. Epub 2002 Jul 11. PMID: 12115094.Fritz JM, McDonald JR. Osteomyelitis: approach to diagnosis and treatment. Phys Sportsmed. 2008 Dec;36(1):nihpa116823. doi: 10.3810/psm.2008.12.11. PMID: 19652694; PMCID: PMC2696389.Hatzenbuehler J, Pulling TJ. Diagnosis and management of osteomyelitis. Am Fam Physician. 2011 Nov 1;84(9):1027-33. PMID: 22046943.Hofstee MI, Muthukrishnan G, Atkins GJ, Riool M, Thompson K, Morgenstern M, Stoddart MJ, Richards RG, Zaat SAJ, Moriarty TF. Current Concepts of Osteomyelitis: From Pathologic Mechanisms to Advanced Research Methods. Am J Pathol. 2020 Jun;190(6):1151-1163. doi: 10.1016/j.ajpath.2020.02.007. Epub 2020 Mar 16. PMID: 32194053.Momodu II, Savaliya V. Osteomyelitis. [Updated 2023 May 31]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK532250/Royalty-free music used for this episode: Trap Chiller by Gushito, downloaded on Nov 06, 2023, from https://www.videvo.net 

Travel Medicine Podcast
1036 The Dirt Man

Travel Medicine Podcast

Play Episode Listen Later Jun 29, 2024 39:02


In this episode, Dr's J and Santhosh discuss why they keep a little dirt under their pillow for the dirt man! Along the way, they cover millennial earworms, the dirt man song, the four classes of soil borne disease, new jersey and the history of streptomycin, Bob dole, citizen science, malicidins, metagenomics, drug resistance in soil, selfish bacteria, geophagy, open verse challenges, nautical dirt and more! SO sit back and relax as we build an entire episode out of a tiktok song!Further Readinghttps://pubmed.ncbi.nlm.nih.gov/22956709/#:~:text=In%20addition%20to%20tetanus%2C%20anthrax,soil%20and%20near%2Dsoil%20environments.https://directorsblog.nih.gov/2018/02/20/powerful-antibiotics-found-in-dirt/#:~:text=Recently%2C%20NIH%2Dfunded%20researchers%20discovered,MRSA)%20skin%20infections%20in%20rats.https://www.drugsfromdirt.org/https://ourworld.unu.edu/en/soil-bacteria-offer-clues-to-curbing-antibiotic-resistancehttps://www.jabfm.org/content/25/5/734.longhttps://www.amazon.com/edible-dirt/s?k=edible+dirtSupport Us spiritually, emotionally or financially here! or on ACAST+travelmedicinepodcast.comX/Twitter: @doctorjcomedy @toshyfroTikotok: DrjtoksmedicineGmail: travelmedicinepodcast@gmail.comSpotify: https://open.spotify.com/show/28uQe3cYGrTLhP6X0zyEhTFacebook: facebook.com/travelmedicinepodcastPatreon: https://www.patreon.com/travelmedicinepodcast Supporting us monthly has all sorts of perks! You get ad free episodes, bonus musical parody, behind the scenes conversations not available to regular folks and more!! Your support helps us to pay for more guest interviews, better equipment, and behind the scenes people who know what they are doing! https://plus.acast.com/s/travelmedicinepodcast. Hosted on Acast. See acast.com/privacy for more information.

NSPR Headlines
Grand Jury finds poor staph infection screening at Shasta County Jail

NSPR Headlines

Play Episode Listen Later Jun 20, 2024 4:55


A report from the Shasta County Grand Jury found that inmates at the local jail were not properly screened or treated for MRSA, a staph infection that is contagious and prevalent in jails, prisons and hospitals. Also, the city of Oroville is looking to overhaul the way citizens report non-emergency needs, and Butte County will hold two more community meetings about a new program to provide no-cost building plans that are suitable for disaster recovery housing.

The Plant Free MD with Dr Anthony Chaffee: A Carnivore Podcast
Episode 218: "I Ate ONLY ONE Food And My Parkinson's REVERSED!" | Mimi Morgan

The Plant Free MD with Dr Anthony Chaffee: A Carnivore Podcast

Play Episode Listen Later Jun 17, 2024 70:57


Mimi Morgan is a remarkable survivor, having overcome rheumatoid arthritis, Parkinson's disease, stroke, and spinal MRSA. Embracing a carnivorous lifestyle, she lives by nature rather than the social system. Mimi is not only an artist and equestrian but also an adventurer who enjoys lifting weights and taking cold swims, all while being completely free of medications. Tune into the PlantFreeMD Podcast's latest episode to hear her complete story! X @mimikmorgan IG @mimimorgank   ✅ Brand Ambassador for Stone and Spear tallow and soaps referral link https://www.stoneandspeartallow.com/?ref=gx0gql8b Discount Code "CHAFFEE" for 10% off ✅Join my PATREON for early releases, bonus content, and weekly Zoom meetings! https://www.patreon.com/AnthonyChaffeeMD ✅Sign up for our 30-day carnivore challenge and group here! https://www.howtocarnivore.com/ ✅Stockman Steaks, Australia Discount link for home delivered frozen grass-fed and grass finished pasture raised meat locally sourced here in Australia! Use discount code "CHAFFEE" for free gift with qualifying orders! http://www.stockmansteaks.com.au/chaffee ✅ 60-minute consultation with Dr Chaffee https://calendly.com/anthonychaffeemd/60-minute-consultation   Sponsors and Affiliates: ✅ Brand Ambassador for Stone and Spear tallow and soaps referral link https://www.stoneandspeartallow.com/?ref=gx0gql8b Discount Code "CHAFFEE" for 10% off ✅ Carnivore t-shirts from the Plant Free MD  www.plantfreetees.com ✅THE CARNIVORE BAR: Discount Code "Anthony" for 10% off all orders!   https://the-carnivore-bar.myshopify.com/?sca_ref=1743809.v3IrTuyDIi ✅Schwank Grill (Natural Gas or Propane) https://glnk.io/503n/anthonychaffeemd $150 OFF with Discount Code: ANTHONYMD ✅X3 bar system with discount code "DRCHAFFEE" https://www.kqzyfj.com/click-100676052-13511487 ✅Cerule Stem cells https://DrChaffee.cerule.com ✅CARNIVORE CRISPS: Discount Code "DRCHAFFEEMD" for 10% off all orders! www.carnivorecrisps.com ✅Shop Amazon https://www.amazon.com/shop/anthonychaffeemd?ref=ac_inf_hm_vp   And please like and subscribe to my podcast here and Apple/Google podcasts, as well as my YouTube Channel to get updates on all new content, and please consider giving a 5-star rating as it really helps!   This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions.  

Dream Chasers and Eccentrics
Britton Kelley, Personal Training and Lifestyle Change

Dream Chasers and Eccentrics

Play Episode Listen Later Jun 13, 2024 71:32


Britton Kelley is a personal trainer living in Medellin Colombia. We  talk about travelling, living in Medellin Colombia, being a gringo, doing your own thing, Costa Rica, lifestyle change, Thialand, fitness, personal training, not having children, OMAD (one meal a day), MRSA, pain, Covid, not watching television, and more. Shownotes can be found at https://www.paultrammell.com/dream-chasers-and-eccentrics

The WorldView in 5 Minutes
“Unsung Hero” is a must-see Christian movie, Chinese Bible distributor sentenced to 5 years in prison, Supreme Court agrees with Texas' age requirement for porn

The WorldView in 5 Minutes

Play Episode Listen Later May 3, 2024


It's Friday, May 3rd, A.D. 2024. This is The Worldview in 5 Minutes heard at www.TheWorldview.com. I'm Adam McManus. (Adam@TheWorldview.com) By Adam McManus Open Doors ministers to Ethiopian woman who lost everything Desta Alemu knows what it's like to be hated and cast out for her faith in Jesus. After all, she has the ashes of her burned home and business to prove it. She and her family were caught up in violence in their community in Ethiopia. She said, “When we left our home, it was very difficult. We couldn't even find a way to get out; we hid in a neighbor's house three houses down. I can't explain the pain and worry I felt in the chaos. Our possessions were destroyed; we lost everything.” Thankfully, Open Doors was able to help her with both immediate needs—and long-term trauma care. Desta explained, “Because I came [to the trauma care seminar], countless things have changed in me. I've learned about humility, and how Jesus was also persecuted. … Jesus was also hated, and He was also cast out.” In John 15:18-19, Jesus said, “If the world hates you, keep in mind that it hated Me first. If you belonged to the world, it would love you as its own. As it is, you do not belong to the world, but I have chosen you out of the world. That is why the world hates you.” Open Doors lists Ethiopia as the 32nd most dangerous country worldwide in which to be a Christian. Chinese Bible distributor sentenced to 5 years in prison In April 2021, Chinese authorities arrested 10 Christians for selling and distributing Bibles in Hohhot, the capital city of Inner Mongolia — an autonomous region in northern China. Just last month, a judge sentenced one of these believers to prison. On April 15, 2024, Ban Yanhong was sentenced to five years in prison for “illegal business operations.” That's how the Communist government describes the distribution of Bibles to Christians in Inner Mongolia. Originally, the 10 Hohhot Christians purchased the Bibles legally from a church in Nanjing associated with the Three-Self Patriotic Movement. These churches are the only legal churches in China and are controlled by the Communist government. In Ban's case, prosecutors argued that even though the Bibles were initially purchased legally in Nanjing, selling and distributing them in Inner Mongolia by unregistered house church members was illegal. Supreme Court agrees with Texas' age requirement for porn Great news! The United States Supreme Court has rejected a request to block enforcement of a Texas law that requires porn sites to verify the age of its users. This will ensure that far fewer minors will have access to these ungodly images. In a one-sentence miscellaneous order released Tuesday that included no dissents, the Supreme Court declined to issue a stay in the case of Free Speech Coalition v. Paxton. This allows a ruling from a three-judge panel of the U.S. Court of Appeals for the Fifth Circuit that upheld the age verification law to remain in effect. Last June, Texas Republican Governor Greg Abbott signed House Bill 1181, which requires porn sites to verify a user's age. Any company found violating the requirement faces a fine of as much as $10,000 per day. Additionally, a porn company can be fined $250,000 if a minor sees explicit content because their age was not properly verified. Second Boeing whistleblower died unexpectedly A second Boeing whistleblower has died unexpectedly as the company faces scrutiny over safety failures on its passenger jets, reports Fox News. Joshua Dean, a quality inspector for the Boeing supplier Spirit AeroSystems, died this week after a surprise infection left him in critical condition for days. The cause was MRSA, an antibiotic-resistant staph infection, according to what his aunt Carol Parsons told the Seattle Times, which first reported the death. The 44-year-old lost his job in 2023 and filed a retaliation complaint with federal labor officials, alleging that he was only fired for speaking out. Dean had been deposed in connection with a shareholder lawsuit and had reported dangerous faults in components of Boeing's 737 MAX plane — a model linked to a number of catastrophes in recent years. John Barnett, age 62, is the other Boeing whistleblower.  He had sued Boeing, claiming that he had been retaliated against, harassed, and spied on by the company. He never showed up for his second day of depositions. Barnett was found dead from an apparent self-inflicted gunshot wound on March 9 outside his Charleston, South Carolina hotel the day after he gave a deposition in connection with his own retaliation lawsuit. “Unsung Hero” is a must-see Christian movie And finally, Joel and Luke Smallbone, the Australian duo that make up the Grammy Award-winning group for King and Country, and their older sister, artist Rebecca St. James, are widely known in music circles. But their family's backstory — and unlikely rise to fame — hasn't been told in-depth and in all its glorious messiness, until now.  The Christian movie, “Unsung Hero,” explores the remarkable journey of the Smallbone family as they relocate from Australia to America in search of new beginnings, reports The Christian Post. After the collapse of his music business, David Smallbone, portrayed by a bespectacled Joel Smallbone, finds himself in a challenging position. Together with his pregnant wife, Helen, the “unsung hero” portrayed by Daisy Betts and their six children, they embark on a transcontinental journey, armed with little more than their luggage and a steadfast belief in their musical dreams. The company behind it also released “Jesus Revolution,” “I Can Only Imagine” and “Ordinary Angels.” A wholesome, faith-based film, “Unsung Hero” focuses largely on the power of prayer. In Philippians 4:6, the Apostle Paul wrote, “Do not be anxious about anything, but in everything, by prayer and supplication with thanksgiving, let your requests be made known to God.” “Unsung Hero” also underscores the necessity of a vibrant church community, and the importance of family sticking together against all odds.  James Smallbone, David's father, reminds his son, “Your family isn't in the way, they are the way.” I saw it with my bride, Amy, and our three children Tuesday night.  It is terrific and very moving. I urge you to get your tickets ASAP since it will only be in the theaters through Wednesday, May 8th. Watch the trailer through a special link in our transcript today at www.TheWorldview.com and visit the website, UnsungHero.movie. Close And that's The Worldview in 5 Minutes on this Friday, May 3rd in the year of our Lord 2024. Subscribe by iTunes or email to our unique Christian newscast at www.TheWorldview.com. Or get the Generations app through Google Play or The App Store. I'm Adam McManus (Adam@TheWorldview.com). Seize the day for Jesus Christ.

S2 Underground
The Wire - May 2, 2024

S2 Underground

Play Episode Listen Later May 2, 2024 1:52


//The Wire//1800Z May 02, 2024////ROUTINE////BLUF: U.S. HOUSE PASSES H.R. 6090. SECOND BOEING WHISTLEBLOWER DIES UNEXPECTEDLY.// -----BEGIN TEARLINE------International Events-Middle East: Turkey has announced the severing of economic ties with Israel. AC: If this is true, and Turkey really does intend to shut down trade with Israel, this could be a significant development as Turkey is/was a major trade partner for Israel. Additionally, the move appears to include the total restriction of Israel's use of the port of Cehyan, which Israel depends on for oil shipments from Azerbaijan.-HomeFront-Washington D.C. – Last night, H.R. 6090 was overwhelmingly passed by the House of Representatives. The bill now heads to the Senate.California: LACOFD Station 164 in Huntington Park caught fire last night, resulting in a two alarm fire at the fire station. AC: The fire caused significant damage to the fire station, which will be out-of-action for the foreseeable future.Kansas: Boeing whistleblower Joshua Dean has died after being hospitalized in Wichita following a sudden series of infections, pneumonia, and MRSA. Dean was airlifted to Oklahoma City Tuesday night, where he died shortly after. He was 45 years old. AC: Dean was taking part in proceedings against Boeing and Spirit Aerosystems, after being fired by Spirit for exposing safety problems within the assembly process for the Boeing 787 Dreamliner.-----END TEARLINE-----Analyst Comments: Reading the contents of H.R. 6090 (to include the definitions contained within) is extremely recommended for all Americans. This bill will, without question, have the exact opposite intended effect on the desired audience. In addition to strengthening resolve, this bill now causes questions to be asked that can no longer be avoided by average citizens and pundits alike.Analyst: S2A1//END REPORT//

Elitefts Table Talk podcast
#275 Jaden Lacaria, Nydir Hayden, Josh Gallone | Meet Prep, Ghost Clash

Elitefts Table Talk podcast

Play Episode Listen Later Apr 16, 2024 134:57


elitefts Limited Edition Apparel: https://www.elitefts.com/shop/apparel/limited-edition.html              Support and help the Podcast grow by Joining The Crew:  https://www.elitefts.com/join-the-crew          Note: The best all-around training bands ever: https://www.elitefts.com/shop/bands.html   In this 275th episode of Dave Tate's Table Talk, Jaden Lacaria, Nydir Hayden, and Josh Gallone join us. Welcome, Jaden, Nydir, and Josh!    Jaden Lacaria has been competing in powerlifting for six years in both multi-ply and raw categories, achieving multiple pro totals in the 198 weight class for each style. His best lifts in the raw 198 category are a 830-pound squat, 450-pound bench press, and 678-pound deadlift. Formerly, he trained at Westside Barbell under Louie Simmons. In addition to powerlifting, Jaden has competed in bodybuilding for two years, with a highlight second place finish at the 2021 NPC North Americans. He aspires to secure his IFBB pro card at this year's NPC North Americans in Pittsburgh, PA. In 2022, Jaden faced a significant setback, tearing both quad tendons and undergoing five surgeries due to a MRSA infection. He now works full-time as an online coach for powerlifting and bodybuilding, traveling across the country to coach at meets and shows. Jaden holds a bachelor's degree and a master's degree in Sports Coaching from The Ohio State University.   Jaden's IG: https://www.instagram.com/jadenlacaria/   Nydir Hayden, a 28-year-old Philadelphia native from Germantown, has been an Advanced EMT in the city's 911 system for nine years and is a father of two. Throughout his youth, he engaged in various sports including football, track, boxing, and martial arts. Nydir began powerlifting in 2017 after being introduced to the sport by a colleague in the fire department. Under the guidance of his coach, Jaden, he transitioned his focus to achieving a professional total and an all-time world record (ATWR) squat at 82.5kg/181lbs. Over the past two years, Nydir has competed in three professional meets, securing best lifter honors and a pro total. He concluded 2023 with a 771-pound squat, the highest wrapped squat in his weight class and ranking him 19th all-time in the 181-pound category.   Nydir's IG: https://www.instagram.com/only1hayden__/   Josh Gallone, 28, resides in the suburbs of Philadelphia and is a family man with a wife and one-year-old son. He started powerlifting in his senior year of high school, driven by the desire to build strength after recovering from an accidental shooting injury. Josh's motivation in powerlifting is to create a legacy that his children can admire. He has been actively competing and striving to enhance his skills in the sport since his high school days.   Josh's IG: https://www.instagram.com/joshgallone/   #dtttp     ABOUT THE HOST   Dave Tate is the founder and co-owner of elitefts.com. He is the author of twenty books and has logged more than 40,000 hours of training and consulting. Dave is married to elitefts co-owner Traci Arnold-Tate, and they reside in London, Ohio, with their two sons. Personal Credo: Live, Learn, Pass on™.   Dave's IG: https://www.instagram.com/underthebar/?hl=en           SPONSORS       elitefts   If you can put it in a gym bag or load weight on it, we have you covered.     https://www.elitefts.com/     Use Code TABLE TALK for 10% off your first elitefts order.           SUPPORT THE SHOW   All profits from elitefts Limited Edition Apparel, Table Talk Coffee, and Team elitefts Workouts, Programs, and Training eBooks support Dave Tate's Table Talk Podcast. Shop these elitefts items: https://www.elitefts.com/content/table-talk/       Support Dave Tate's Table Talk podcast by joining the crew.  https://whop.com/tabletalkcrew/        elitefts Shop: https://www.elitefts.com/        elitefts IG: https://www.instagram.com/elitefts/          SPONSORSHIP/PODCAST INQUIRIES   For sponsorships or business inquiries, reach out to tabletalkmedia@elitefts.net    For Podcast inquiries, please DM @elitefts on Instagram or email tabletalkguest@elitefts.net     #DDTTTP   #DTTTP   #ddttp

Vitality Radio Podcast with Jared St. Clair
#413: Common Misconceptions About Colloidal Silver and the Power of Topical Silver Gel with Keith Moeller

Vitality Radio Podcast with Jared St. Clair

Play Episode Listen Later Mar 16, 2024 58:58


Colloidal Silver might be the most criticized natural product out there. The truth is, it's one of the most clinically studied! On this episode of Vitality Radio, Jared brings Keith Moeller back to the show to talk about the most common misconceptions about the safety of all types of silver and what type has the most clinical research backing its efficacy. You'll also learn about Vitality Nutrition's new Nano-Silver Skin Gel, its many uses, and the research behind it. Keith Moeller, ND is CEO and a founder of SilverCeuticals Inc. with almost 40 years of experience working in the silver industry. He has co-authored many papers, textbooks, and other publications on silver, a number of which have been peer-reviewed and published in leading wound care, science, and health journals.Products:Nano-Silver ProductsAdditional Information:Silver - Nature's Natural Healer (free digital book)#367: Your Silver User's Guide: Colloidal, Ionic, Nano…What Does It All Mean, Is It Safe, And Does It Work?Visit the podcast website here: VitalityRadio.comYou can follow @vitalityradio and @vitalitynutritionbountiful on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Please also join us on the Dearly Discarded Podcast with Jared St. Clair.Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

Toucher & Rich
“I'm neggin' ya, babe” | What Happened Last Night | C's beat Pacers, 129-124 - 1/31 (Hour 1)

Toucher & Rich

Play Episode Listen Later Jan 31, 2024 44:40


(00:00) Fred opens the show discussing the time Nick's now wife found him almost dead covered in poo (side note: I did, in fact, almost die from MRSA and had to get open-heart surgery to repair my heart). Wallach has grown out his goatee to relive his glory days. (15:34) WHAT HAPPENED LAST NIGHT: After a tough third quarter, the Celtics recovered to claim their second win in a row by beating the Pacers, 129-124.  CONNECT WITH TOUCHER & HARDY: linktr.ee/ToucherandHardy For the latest, Visit the show page on 985thesportshub.com. Follow 98.5 the Sports Hub on Twitter, Facebook and Instagram! Visit our channels on Twitch and Youtube!