Podcasts about mrsa

This week Elizabeth scores a huge win in the kitchen, Andy misinterprets a rock skipping headline, MRSA is dodged, a heartwarming message arrives in a special box, and much more! It's all covered on this week's Nobody's Listening, Right? BETH'S DEAD launches October 30th!  Learn more at: https://www.patreon.com/cw/BethsDead Support NLR Join Patreon for bonus episodes! Buy the Merch! Find us on Instagram Find us on TikTok⁠⁠ Watch us on YouTube Shop our Amazon recommendations Here ▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬ Chapters: 00:00 Intro 00:38 Short King 01:12 Giant Maine Coon Pussy Cats 02:47 Small But Mighty 04:01 You Can't Stop The Shrinking 05:42 A Heartwarming Update 11:22 Moving Boxes 12:30 Goodbye Dirty Grout 14:55 Your First Magic Eraser 18:11 Beth's Dead Announcement 24:25 A Misleading Headline? 24:57 World Stone Skimming Cheating Scandal 34:19 MIDROLL 38:24 Childhood Crush 40:54 Grocery Stories 46:25 Mersa 52:30 Elizabeth's Oil Painting 54:21 Duo Done? Learn more about your ad choices. Visit podcastchoices.com/adchoices

In today's podcast CesarRespino.com brings to you a special guest to the show...Lyndsay's journey is one of resilience and empowerment. After losing her leg to an MRSA infection, she founded Neo Walk, a company dedicated to creating stylish, acrylic walking sticks for people living with disabilities. Her goal was to design a walking aid she would feel confident using, and it all started in her kitchen. Today, Neo Walk ships to over 28 countries, offering a range of designs, including light-up models, all aimed at helping individuals rediscover their confidence and style.In 2023, Neo Walk earned recognition with both a National Diversity Award and a Women in Business Award, reflecting its impact. The brand's walking sticks have even graced the red carpet through collaborations with Hollywood stylists, proving that mobility aids can be both functional and fashionable. Lyndsay's story demonstrates how adversity can spark innovation, turning personal challenges into a platform for creating positive change.Lynsay Mitcheson message to you is:Challenges are opportunities in disguise. If you approach adversity with creativity and resilience, you can turn it into something that not only changes your life, but also the lives of others.To Connect with Lyndsay go to:Instagram- @neowalksticksFacebook- www.facebook.com/neowalkWebsite- https://neo-walk.com/To Connect with CesarRespino go to:

Jessica Sheldon (PhD) is on a mission to starve out Acinetobacter baumannii —one of the world's most virulent hospital-borne pathogens. Notorious for its speedy evolution and multi-drug resistance, the hospital-borne bacteria lingers on dry surfaces and infects critically-ill patients, leading to sepsis, pneumonia and high mortality rates. In this episode, Sheldon delves into the real-life events that drove her to investigate histamine, and its role in bacterial survival and immune response. In 2022, Sheldon joined the University of Saskatchewan's College of Medicine as an assistant professor of Biochemistry, Microbiology & Immunology -- something she now laughs about after an ill-fated high school placement in an immunology laboratory. “Cytokine cascades, pathways, the signaling just got way over my head real fast,” said Sheldon. “I didn't really know what I was doing.” Sheldon enrolled at Lakehead University, drawn to the tiny pathogens with outsized roles in movies like Outbreak. She estimates she read the book The Hot Zone 20 times. Her persistence paid off. “One of my second year microbiology teachers said, ‘you know, I think you're kind of good at this. Maybe you should try it as a career.' Sheldon zeroed in on metals and wrote her doctoral dissertation on the role iron plays in the proliferation of bacteria such as Methicillin-resistant staphylococcus aureus (MRSA). Today, she studies both Morganella morganii and Acinetobacter baumannii —  the multi-drug-resistant bacteria singled out twice in the last decade by the World Health Organization as a ‘priority 1-critical pathogen'. “I'm perpetually fascinated by the idea that something so small can change the course of history,” said Sheldon. “And we've seen that recently with COVID.” Sheldon was already studying the metal uptake and signalling systems that grow and sustain A. baumannii when the bacteria ripped through hospitals during the pandemic, attacking Covid-infected patients on ventilators. By 2023, Sheldon landed a five-year CIHR grant of $900,000 to study A. Baumannii and the way it turns histidine into histamine. Her goal is to pinpoint the way the pathogen uses histamine to evade its host, as it sends out siderophores to steal iron and other nutrients. The compound appears to serve as a signalling mechanism for both the host and the invading pathogen, she said. “We know the bacteria are using histamine in the synthesis of these molecules to get iron, but they're also secreting it into the environment. We're not really sure why,” Sheldon said. Her laboratory is working to trace and target those pathways, so researchers can identify and potentially develop new treatments — small molecules or antibody inhibitors that could disrupt multi-drug resistant pathogens. Beyond A. baumannii, histamine may hold the key to how some of the world's most notorious bacteria grow, spread, and evade immune defences, Sheldon said. “We're running out of drugs, but there's really not a full appreciation for the fact that we're losing the ability to treat bacterial infections,” Sheldon said.  “We need to develop supplementary therapies or alternative therapies.”

Zosyn (piperacillin/tazobactam) is a broad-spectrum β-lactam/β-lactamase inhibitor combination used widely in hospitals. Piperacillin covers gram-positive, gram-negative, and anaerobic bacteria, while tazobactam helps protect against β-lactamase breakdown. It is commonly used for pneumonia, intra-abdominal infections, skin and soft tissue infections, and febrile neutropenia. An important pharmacology pearl for exams is understanding that Pseudomonas, but it doesn't cover MRSA. The drug is renally eliminated, so dosing adjustments are needed in kidney impairment. Many institutions use extended or prolonged infusions to maximize time above the MIC, which can improve efficacy. Standard dosing is 3.375 g to 4.5 g every 6–8 hours, with modifications for dialysis patients. Adverse effects include hypersensitivity, gastrointestinal upset, electrolyte imbalances like hypokalemia, and blood count changes with prolonged therapy. A key clinical concern is nephrotoxicity risk, especially when used with vancomycin. Monitoring renal function and electrolytes are important. Methotrexate and probenecid are two medications that can interact with Zosyn. Concentrations of Zosyn can be increased when these medications are used in combination.

Send us a textWARNING: VERY GRAPHIC AND GORY DESCRIPTIONS OF HARROWING MOMENTS.Jay Setchell has been dead 3 times. In 1969 in the Marines, in 1973 by a DUI driver, and then a third time in 1981, a swimming pool incident, involving drowning, multiple broken vertebrae in neck, and paralyzed from shoulders down.This really is an insane episode and not for the faint hearted, but Jay is HERE to tell his ongoing story! Beyond this, Jay was close to dying from blood borne MRSA staph infection in 2004, and his wife was told to go home and make funeral arrangements from Covid Delta in 2021. 73 surgeries and counting and after everything, Jay NEVER stopped trying. Whether it's courage, grit, perseverance, determination, anger, pain, or just being pissed off, Jay's mantra is “it's always too soon to quit”! Jay is 75 1/2 as describes life as a gift,  even with being largely paralyzed, and in immense amounts of pain on a daily even an hour basis. Jay has been divorced twice, married 3rd times, has adopted kids, natural kids, step kids, and many grandkids!! Join us to hear Jay's outlook on life today!Breaking Free from Narcissistic AbuseWhen love turns toxic, this podcast helps you make sense of the chaos and start to heal.Listen on: Apple Podcasts SpotifySupport the show

Welcome to another episode of the Sustainable Clinical Medicine Podcast! In this episode, Dr. Sarah Smith sits down with Dr. Jeff Cohn, a retired hematologist-oncologist whose journey took him from the patient bedside to the halls of hospital leadership and, ultimately, to coaching fellow physicians. Dr. Cohn shares deeply moving stories from his clinical days—like orchestrating a final, meaningful anniversary for two dying patients—as well as the challenges and motivations that led him to transition into healthcare quality improvement. Through engaging anecdotes, Dr. Cohn reveals how he championed transformative approaches to organizational change, particularly the innovative use of “positive deviance” to tackle MRSA infections in the hospital. He explains how listening to frontline healthcare workers and drawing out internal best practices led to remarkable reductions in hospital-acquired infections—by 85%! Along the way, you'll learn about practical facilitative techniques, such as “liberating structures,” that empower teams and ensure every voice is heard. The episode also delves into the realities of clinician burnout, the complexities of driving system-wide change, and Dr. Cohn's current passion: coaching physicians in positive intelligence and mental fitness. Whether you're a healthcare professional or simply interested in sustainable, people-centered medicine, this conversation offers inspiring perspectives and actionable insights on making systems—and ourselves—work better. Here are 3 key takeaways from this episode: Harnessing Frontline Wisdom: Dr. Cohn described the transformative power of inviting frontline staff to identify solutions—a process called “positive deviance.” By genuinely asking nurses, transporters, and other care team members for their ideas (and truly listening), his organization achieved an 85% reduction in MRSA infections, all through internally sourced solutions. Liberating Structures Make Meetings Matter: Traditional hospital meetings too often drain energy and stifle creativity. Dr. Cohn's team used “liberating structures”—simple yet structured facilitation tools—to ensure every voice was heard, which sparked engagement and uncovered innovative solutions. Prioritizing Wellbeing for Sustainable Change: Through his coaching work, Dr. Cohn now helps physicians leverage mental fitness and positive psychology. He emphasizes that systemic change should support—not overwhelm—the clinical workforce, and that even within challenging systems, there are individuals and habits from which we can all learn. Meet Dr. Jeff Cohn: I'm a native Philadelphian, trained as a hematologist/medical oncologist. I practiced/taught/did clinical research full-time for the first 15 years of my career. I then was asked to assume various non-clinical roles (division head, interim Chair of Internal Medicine, Chief Quality Officer). The Chief Quality Officer role ultimately became a full-time role and I held that position for 12 years. Since then I've led a non-profit organization for three years (Plexus Institute) and worked with a couple of design teams as the medical director. I'm now working as a Mental Fitness and Leadership coach with physicians. Along the way I obtained a Masters in Healthcare Management from Harvard School of Public Health. You can find Dr. Jeff Cohn on: Linked In: https://www.linkedin.com/in/jeff-cohn-2738b82b/ Website: https://caretochangecoaching.com/ -------------- Would you like to view a transcript of this episode? Click Here **** Charting Champions is a premiere, lifetime access Physician only program that is helping Physicians get home with today's work done. All the proven tools, support and community you need to create time for your life outside of medicine. Learn more at https://www.chartingcoach.ca **** Enjoying this podcast? Please share it with someone who would benefit. Also, don't forget to hit “follow” so you get all the new episodes as soon as they are released. **** Come hang out with me on Facebook or Instagram. Follow me @chartingcoach to get more practical tools to help you create sustainable clinical medicine in your life. **** Questions? Comments? Want to share how this podcast has helped you? Shoot me an email at admin@reachcareercoaching.ca. I would love to hear from you.

A Plan To Get Rid Of All The Cats Dr. Gareth Morgan wants to rid New Zealand of all the cats. He says they're damaging the bird population. Is he crazy, or does he have a point? We'll speak with him and find out what he's thinking and the adversity he's facing with his plan. Listen Now The Hard To Train Dog Peggy Swager has dedicated her life to the "hard-to-train" dog. She will tell us about her toughest cases and how to manage a dog that just won't behave properly. We'll have tips for overcoming problem behaviors and giveaways of her book. Listen Now Poison In Your House Dr. Justine Lee works at the Pet Poison Helpline. She says the top 5 pet toxins are probably in your house and accessible to your furry-friend. Dr. Lee will tell you what to watch out for and how to treat a pet that has eaten something poisonous. Listen Now Bully Sticks Condemned Turns out there's a lot more inside a popular dog treat than most pet owners probably imagine. They're called "pizzle" sticks or "bully" sticks, and a new study out of Canada says they're loaded with calories and bacteria. The treat is made from uncooked, dried bull penis, and researchers say it can contain things like E. coli and MRSA. Listen Now Iran Launches Monkey Into Space Iran said it launched a live monkey into space, seeking to show off its missile systems. "This shipment returned safely to Earth with the anticipated speed along with the live organism," Defense Minister Ahmad Vahidi told the semi-official Fars news agency. However, comparative pictures of the monkey don't match. Listen Now Read more about this week's show.

Don't Play in that nasty flood water in Charleston!

AI models have helped to discover new potential antibiotics to treat drug resistant infections of gonorrhoea and MRSA. We speak to Professor Jim Collins from MIT to understand what's next for his machine-generated medicines and the role AI could play in the future of drug discovery. A new report has found high rates of bloodstream infections and antibiotic resistance in central lines used in Indian ICUs. Family doctor Ann Robinson joins Claudia to understand the risks posed to already vulnerable patients. We consider a new review that found no evidence ketamine is effective at helping those with chronic pain, despite it being prescribed off-label for this use in some countries. Rwandan MPs have approved lowering the age adolescents can access sexual and reproductive health services without parental consent from 18 to 15. We catch up with BBC reporter Dorcas Wangira on what this could mean for the health of adolescents and the fallout of the decision in Rwanda. Finally, people with diabetes in India have long been told to steer clear of mangoes - Ann and Claudia unpick whether this advice needs to change. Presenter: Claudia Hammond Producer: Hannah Robins Assistant Producer: Katie Tomsett

In his new book Outbreak Behind Bars: Spider Bites, Human Rights, and the Unseen Danger to Public Health, physician and epidemiologist Dr. Homer Venters reveals the grave reality of how infections and diseases spread in correctional facilities, which are often overcrowded and unsanitary. Detailing first-hand accounts of the spread of tuberculosis, MRSA, and other infections, he shines a light on the critical need to improve health care behind bars.   Venters was the chief medical officer of the New York City jail system and is currently a federal monitor of health services in jails and prisons.    Listen to him in conversation with Dr. Josy Hahn, senior research fellow, manager, and social epidemiologist in the Brennan Center's Justice Program.  Recorded on July 28, 2025.  Keep up with the Brennan Center's work by subscribing to our weekly newsletter, The Briefing, at https://go.brennancenter.org/briefing. 

  Lyndsay Mitcheson's BIO:    Lyndsay's journey is one of resilience, creativity, and transformation. After losing her leg to an MRSA infection, she set out to design a walking stick she could feel proud to use. What began in her kitchen became Neo Walk, a bold brand of stylish, colourful acrylic walking sticks that empower people living with disabilities to embrace their mobility with confidence and pride. Neo Walk now ships to over 28 countries and offers a wide range of designs—from sleek classics to light-up statement pieces—redefining what mobility aids can look and feel like. Lyndsay's mission is simple but powerful: to make walking sticks that people want to use. In 2023, Neo Walk received both a National Diversity Award and a Women in Business Award, and its unique designs have even appeared on red carpets through collaborations with Hollywood stylists. Lyndsay's story is a powerful reminder that personal challenges can spark meaningful change—and that mobility aids can be more than functional; they can be beautiful, bold, and proudly carried.   In this episode, Virginia and Lyndsay talked about: How Lyndsay turned personal adversity into a thriving global brand The power of word-of-mouth and networking in building a business Why brand credibility starts with authentic relationships Leveraging strategic partnerships to reach new markets Balancing purpose, service, and profitability in entrepreneurship   Takeaway: Your challenges don't define you, your response does. Strategic relationships can open doors, marketing can't. Word-of-mouth is still one of the most powerful growth tools. Your brand's credibility is built through connection not just promotion. Visibility creates possibility. Be seen to inspire the next generation.   Connect with Lyndsay on his social media accounts to learn more about his work and insights into networking effectively: Facebook URL: https://www.facebook.com/neowalk.neowalk/photos/ Instagram URL: https://www.instagram.com/neowalksticks/    Connect with Virginia: https://www.bbrpodcast.com/

One of the greatest medical breakthroughs of the twentieth century is set to become one of the biggest threats of the twenty-first - but what can be done to stem the rising tide of antibiotic resistance? In this episode, host Caroline Dodds Pennock speaks with Liam Shaw, biologist and author of Dangerous Miracle: A Natural History of Antibiotics – and How We Burned Through Them. From the miraculous discovery of penicillin to the industrial-scale production that changed healthcare and agriculture forever, Shaw takes us through the fascinating - and cautionary - story of these ‘fossil fuels of medicine.' Together, they explore when and how the threat of resistance emerged, the roles of Big Pharma and industrial farming in accelerating the crisis, and the parallels with climate change in how we've squandered a finite resource. But as MIT researchers recently announced a breakthrough with AI designing antibiotics for gonorrhoea and MRSA superbugs, Shaw also outlines clear roadmaps for the future - including bold proposals for transforming the way we develop, patent and pay for antibiotics. If you'd like to become a Member and get access to all our full conversations, plus all of our Members-only content, just visit intelligencesquared.com/membership to find out more. For £4.99 per month you'll also receive: - Full-length and ad-free Intelligence Squared episodes, wherever you get your podcasts - Bonus Intelligence Squared podcasts, curated feeds and members exclusive series - 15% discount on livestreams and in-person tickets for all Intelligence Squared events  ...  Or Subscribe on Apple for £4.99: - Full-length and ad-free Intelligence Squared podcasts - Bonus Intelligence Squared podcasts, curated feeds and members exclusive series … Already a subscriber? Thank you for supporting our mission to foster honest debate and compelling conversations! Visit intelligencesquared.com to explore all your benefits including ad-free podcasts, exclusive bonus content and early access. … Subscribe to our newsletter here to hear about our latest events, discounts and much more. https://www.intelligencesquared.com/newsletter-signup/ Learn more about your ad choices. Visit podcastchoices.com/adchoices Learn more about your ad choices. Visit podcastchoices.com/adchoices

AI has designed two new potential antibiotics that could tackle tough bacteria, including multi-drug-resistant MRSA and gonorrhoea. Massachusetts Institute of Technology Termeer Professor of Medical Engineering & Science James Collins spoke to Corin Dann.

US President Donald Trump and Russian President Vladimir Putin will travel to a summit in the US state of Alaska on Friday with contrasting priorities as they prepare for talks on ending Russia's war in Ukraine. Mr Trump has said the plan was to "set the table" for a more important second meeting involving Ukrainian President Volodymyr Zelensky. Also: AI designs antibiotics for gonorrhoea and MRSA superbugs, and German states debate who invented Bratwurst sausages.The Global News Podcast brings you the breaking news you need to hear, as it happens. Listen for the latest headlines and current affairs from around the world. Politics, economics, climate, business, technology, health – we cover it all with expert analysis and insight. Get the news that matters, delivered twice a day on weekdays and daily at weekends, plus special bonus episodes reacting to urgent breaking stories. Follow or subscribe now and never miss a moment. Get in touch: globalpodcast@bbc.co.uk

Brought to you by TogetherLetters & Edgewise!In this episode: Flipper Zero DarkWeb Firmware Bypasses Rolling Code SecurityDial-up Internet to be discontinuedAI Firm Perplexity Makes $34.5 Billion Bid For Google's Chrome Browser Anthropic offers Claude chatbot to US lawmakers for $1Sam Altman's new startup wants to merge machines and humansThe ‘godfather of AI' reveals the only way humanity can survive superintelligent AI AI designs antibiotics for gonorrhoea and MRSA superbugs​​AI can make us UK's biggest firm, Rolls-Royce says​​An AI-powered coding tool wiped out a software company's database, then apologized for a ‘catastrophic failure on my part'​​Australian lawyer apologizes for AI-generated errors in murder caseIllinois bans AI therapy as some states begin to scrutinize chatbots​​Women with AI ‘boyfriends' mourn lost love after ‘cold' ChatGPT upgradeReddit will block the Internet Archive

Morse code transcription: vvv vvv Girl who died after Maidenhead hospital failure unlawfully killed Pupil who invented device to help homeless named girl of the year Teenager arrested after death of 13 year old girl in Huddersfield AI designs new superbug killing antibiotics for gonorrhoea and MRSA A level results Why did boys outperform girls for top grades Left out of Alaska talks, Ukrainians fear an unjust peace Cost of weight loss drug Mounjaro may rise significantly VJ Day 80th anniversary King Charles says heroes will never be forgotten Ukraine war US and Russian delegations head to Alaska for crunch talks MasterChef Second contestant edited out of Gregg Wallace and John Torodes final series

美國麻省理工學院最近發表了一項新研究，利用生成式AI設計出兩種，可以抑制具抗藥性的淋病淋球菌和MRSA耐甲氧西林金黃色葡萄球菌，的潛在新抗生素。這新藥物已在實驗室和動物實驗中，成功殺死這些超級細菌，不過還需要數年時間來做臨床實驗，並加以改善，才能正式投入使用。不過研究團隊，抱持信心，表示AI應用將可能開啟抗生素研發的「第二個黃金時代」。 留言告訴我你對這一集的想法： https://open.firstory.me/user/cku2d315gwbbo0947nezjmg86/comments YT收看《寰宇全視界》

Plus Can AI Run A Whole Country?Like this? Get AIDAILY, delivered to your inbox 3x a week. Subscribe to our newsletter at https://aidaily.usAI Could Make Book Reading Obsolete—and Students Have the Most to LoseAI's takeover of book “reading”—through instant summaries, comparisons, and chats with texts—is stripping away the deep engagement, growth, and joy of diving into the real thing. Students may lose critical thinking and the emotional payoff that only actual reading delivers.Could AI Run a Whole County? Albania Wants to Find OutAlbanian PM Edi Rama floated the idea of an AI‑run ministry—maybe even an entire AI government—to kill corruption and fast‑track EU membership. AI already plays a role in procurement, customs, and infrastructure monitoring. But critics warn: if you don't clean the system, AI will just “hide the old dysfunction better.”AI Chef Aiman Is Flipping the Script on Fine Dining in DubaiIn Dubai, an AI named Chef Aiman designs wild, next-level menus using molecular gastronomy smarts—think repurposed scraps, funky flavor combos, and full sensory vibes. Human chefs don't get ghosted—they polish the ideas, making this a collab, not a take-over. Illinois Bans AI as Your Therapist—More States Eye the MoveIllinois just outlawed the use of AI chatbots for therapy, insisting only licensed pros can make treatment decisions—though AI still gets green-lit for desk work. And it's not stopping there: California, New Jersey, and Pennsylvania are all cooking up bills to clamp down on AI's emotional reach.MIT Uses Generative AI to Cook Up Superbug-Killing AntibioticsMIT researchers tapped generative AI to design novel antibiotics—screening over 36 million molecules—to find two standout compounds that crushed gonorrhea and MRSA in lab and mouse tests. These structurally fresh antibiotics could spark a new era in fighting drug-resistant bugs. AI Music Is Ubiquitous and Getting Harder to SpotAI-generated music is everywhere—and it's getting crazy hard to tell the difference from human-made tracks. Detection tech is racing to catch up, but the vibe? Super seamless, borderline invisible.Cheapfake AI Celeb Videos Are Rage-Baiting People on YouTubeYouTube is flooded with cheapfake celeb fan-fiction—static shots + AI voices recreating fake celeb feuds. Viewers, especially older/right-leaning ones, freak out, fueling engagement and clicks. Platforms struggle to flag them as AI-made, and even when policies exist, enforcement is weak.Does AI Really Boost Productivity at Work? Research Shows Gains Don't Come Cheap or EasyTurns out AI productivity boosts are a whole mood—but only if you invest in training, redesign workflows, and rethink how humans and AI tag-team. Without that, efficiency gains stay low-key and expensive. 

No episódio de hoje do Check-up Semanal, Ronaldo Gismondi, editor-chefe médico do Portal Afya e do Whitebook, traz as principais atualizações do mês em Infectologia, com foco em temas que impactam diretamente a tomada de decisão clínica.

Text us a pool question!Borates, pool safety, heat stroke, MRSA, chlorine, health risks, swimming pool maintenance, heat-related illnesses, summer safety, pool infections, public safetyIn this episode of Talking Pools - BORATES! Followed by Andrea on the alarming health risks associated with swimming pools, particularly focusing on a case of a tourist who suffered severe injuries after swimming in a poorly maintained hotel pool. She emphasizes the importance of pool safety and regular maintenance. The conversation then shifts to the serious topic of heat-related illnesses, especially relevant for those working outdoors in hot conditions. Andrea provides practical tips for preventing heat stroke and other heat-related issues, concluding with a reminder about an ongoing design contest for pool industry apparel.TakeawaysA tourist suffered life-changing injuries from a filthy hotel pool.MRSA infections can arise from poorly maintained swimming pools.Regular testing and maintenance of pool water is crucial for safety.Heat-related illnesses are a serious concern during hot months.Hydration is key to preventing heat-related illnesses.Wearing protective clothing can help mitigate heat exposure.Recognizing the symptoms of heat stroke can save lives.Immediate action is necessary when someone shows signs of heat stroke.Heat cramps can indicate more serious heat-related issues.The importance of community awareness in pool safety and health.Sound bites"Call 911 and don't try to help yourself, just immediately call 911.""If you have heat rash, get a different job. Just kidding.""Go follow us on social media and follow me."Chapters00:00 Introduction and Headlines05:55 Health Risks in Swimming Pools08:03 Heat-Related Illnesses Awareness22:05 Contest Announcement and Closing Remarks Support the showThank you so much for listening! You can find us on social media: Facebook Instagram Tik Tok Email us: talkingpools@gmail.com

Dave and Chuck the Freak talk about Dave locking himself out of his office, Dave had to fix his dad’s internet, emailer ran into Weird Al fans in elevator, things that were in the news 10 years ago, the most creative ways to say ‘I have to poop,’ woman gets road rage, bystander who intervened in Walmart stabbing speaks, garbage truck hit a pick up and ripped it open, garbage truck slammed into parked car, woman says she caught MRSA after swimming in hotel pool, 2 women had to save baby horse from river rapids, dancing in drug commercials, NFL HQ was target of shooting, Royals player stung by tee during at-bat, Hulk Hogan tribute on Monday Night Raw, Ozzy Osbourne funeral, Katy Perry dating Justin Trudeau, Pam Anderson and Liam Neeson speculation, Sasha Baron Cohen in shape, Kim Kardashian’s shape wear for your face, Happy Gilmore 2 sets Netflix record, Dave’s deodorant staining his clothes, video of Dasher tasting customer’s food, convicted voyeur arrested for touching himself outside of woman’s window again, guy claims the Lord told him to run crypto scam, cruise passenger falls out of infinity pool, man kicked out of Planet Fitness for toe shoes, what’s the craziest thing you saw in a locker room?, and more! This episode of Dave & Chuck is brought to you in part by Profluent http://bit.ly/4fhEq5l

Don't have time to listen to the entire Dave & Chuck the Freak podcast? Check out some of the tastiest bits of the day, including a woman caught MRSA after swimming in a hotel pool, what’s the craziest thing you’ve seen in a locker room?, what causes hemorrhoids, and more!

Today on the Beautifully Broken Podcast, I'm joined by Steve Revelli of American Biotech Labs—a trusted voice and formulator behind the cutting-edge Silver Biotics product line. We explore the multi-layered benefits of silver nanoparticles, including their powerful antimicrobial action that spares your natural flora while defending against pathogens like MRSA and VRE. Steve breaks down the difference between ionic and colloidal silver, dispels myths, and reveals why parts per million matter far less than particle structure.Whether it's boosting immunity, healing wounds, or enhancing recovery with clean, natural ingredients, silver is showing up as a hero product for families, athletes, and anyone wanting a low-cost, high-impact health tool. This is more than hype—this is healing through science, clarity, and intention. Tune in and discover how to empower your body with silver.Episode Highlights[02:10] - Steve Revelli's journey from education to silver formulation at American Biotech Labs[04:55] - How silver works as both a preservative and an antimicrobial[07:01] - The science behind silver nanoparticles and their unique coating[13:26] - Why Silver Biotics outperforms high ppm ionic silver products[15:52] - Real-world applications of Armor Gel for burns, cuts, and even fungal infections[22:08] - Silver Biotics in athletic programs and hospital burn units[26:28] - Silver's role in immune support and the power of daily microdosing[30:07] - How the Recovery Cream uses hyaluronic acid and silver for transdermal healing[33:55] - Upcoming product lines and oral care innovations[39:51] - Real talk on misinformation, regulation, and why silver deserves a second look[45:12] - Unexpected uses: nasal sprays, ice baths, and biohacking applications[51:06] - The daily regime that keeps Steve (and me) thrivingLINKS & RESOURCESSilver Biotics: https://silverbiotics.com/Use Code: BEAUTIFULLYBROKEN for MASSIVE discountBEAM Minerals: http://beamminerals.com/beautifullybrokenUse Code: BEAUTIFULLYBROKEN for discountStemRegen: https://www.stemregen.co/products/stemregen?_ef_transaction_id=&oid=1&affid=52Code: beautifullybrokenLightPathLED: https://lightpathled.pxf.io/c/3438432/2059835/25794code: beautifullybrokenWork with me:https://www.beautifullybroken.world/biological-blueprint CONNECT WITH FREDDIEWebsite and Store: (http://www.beautifullybroken.world) Instagram: (https://www.instagram.com/beautifullybroken.world/) YouTube: (https://www.youtube.com/@BeautifullyBrokenWorld)

Dr. Ishnella Azad, known simply as Ish, is a psychiatrist-turned-real estate mogul who has lived multiple lives in one. From medicine to commercial real estate to data centers, her journey is fueled by a singular mission: to empower everyday people, especially women, with the tools to build generational wealth and lasting freedom.In this episode, Dr. Azad shares how surviving personal trauma, including a life-altering MRSA infection and amputation, led her to transform her pain into purpose. We talk about trauma, identity, financial literacy, and why she believes economic empowerment is the most powerful form of healing.Her story is raw, bold, and incredibly inspiring, and her message is clear: no matter what life throws at you, just get up.Episode Resources:Dr. Azad's LinkedIn5Rivers CRE WebsiteLink to purchase:FYLPxTracee Badway Merch CollaborationFYLPxWRDSMTH Merch Collaboration*suggestion is to size upDownload this episode of For Your Listening Pleasure wherever you get your podcasts! Make sure you follow us on Instagram @foryourlisteningpleasure Click here to listen to the For Your Listening Pleasure Theme Song Playlist on Spotify.To continue the conversation, feel free to DM me at https://www.instagram.com/foryourlisteningpleasure/ or email me at foryourlisteningpleasure@gmail.com.

Would you have gone to the doctor over this?

What happens after we die? In this powerful episode of "Into the Supernatural with Jen Lilley and Billy Hallowell," author Randy Kay shares his stunning, first-hand account of what happened when he clinically died for over 30 minutes.After suffering from severe blood clots, MRSA infection, and total organ shutdown, Randy flatlined in the hospital—but his story didn't end there. Instead, Randy says his spirit left his body, launching him into an unforgettable journey beyond the veil of this world. He describes encountering angels, witnessing spiritual warfare, seeing Jesus face-to-face, and experiencing God's love in its purest form.You'll hear Randy detail:☑ His spiritual battle between angels and demons over his soul☑ What it felt like to stand in the presence of Jesus☑ The overwhelming love of heaven☑ His life review—where Jesus revealed how prayers, even from strangers, impacted his life☑ The mission Jesus gave him upon returning to earthThis conversation will challenge your faith, ignite your hope, and remind you of the eternal significance of prayer, redemption, and God's unfailing love.Have questions for Randy? Drop them in the comments! We'll bring him back for Part 2, where he'll answer your questions about heaven, angels, near-death experiences, and more.

The "Jason Lanier Unfiltered" podcast is where real talk meets raw creativity, offering unfiltered conversations about photography, life, and the wild journey in between. Host Jason Lanier invites people he works with to share their experiences, making for enlightening and fun discussions. In this particular episode, Jason speaks with model Krystal Kadaver, who has been modeling since she was 18 and has been a frequent collaborator on Jason's project at Six Flags New Orleans.The conversation delves into Krystal's experiences modeling at the abandoned Six Flags park, from seeing its transformation from a Jurassic Park like abanbdoned location to it's current half demolished state. They talk about navigating the challenging environment, including "MRSA water," mosquitoes, and alligators.  They discuss the importance of communication between photographers and models, the significance of a photographer having a clear vision, and the role of models as muses who should bring their own creativity and adaptability to a shoot.  Krystal shares advice for new models, emphasizing research, bringing a friend (a "Jen" who can help, and being prepared to get dirty.They also touch on the challenges and rewards of being a creative and balancing it with personal life, highlighting the need for a supportive partner who understands the passion for creation.... The podcast emphasizes the unique and adventurous nature of shoots with Jason Lanier, where "it's an experience, not just a photo shoot.Chapter Markers00: Intro35: Introduce Guest Star Krystal5:30: What did you think about shooting at Six Flags prior to doing the shoot?6:35: What was it like shooting with me from an expectation vs. reality standpoint?7:45: The Importance of Communicating as a model and a photographer BEFORE the shoot12:07: Struggling to find creative outfits and looks as a photographer14:15: What makes it a no go for Jason with models and communication15:36: The Synergy of Creation16:05: What it means to be a Muse18:18- How to Not Cheat Yourself out of Great Shots20:29: Working with Jason compared to working with other photographers21:30- The Importance of Giving Directions to a Model22:45- How Male Photographers Should Appropriately Compliment a Female Model26:40: How Female Photographers Communicate Differently Than Male Photographers27:25: Learning a Model's Boundaries as a Photographer29:39: Favorite Shoots we did at Six Flags New Orleans32:36: What Advice would you give to models that haven't shot with Jason before?34:35: Setting Off Chinese Dynamite35:57: What Advice would you give to newer models?36:13: Bringing a friend or escort to a shoot41:00: Shooting with Multiple Models on one set45:21: Having a personal life as a creative47:39: Feeling the most alive as a creative51:35: The Importance of Being Who you are as a creative when you're in a relationship53:58: What a Great Photo Shoot should feel like55:40: The Importance of Staying Positive on a Shoot59:00: Wrap up and Future Projects

In the final installment of this season of Titans of Science, Chris Smith speaks with Sharon Peacock, one of the UK's leading voices in infectious disease research. She is best known for her work on whole genome sequencing of pathogens such as MRSA and SARS CoV-2, and studies of antimicrobial resistance... Like this podcast? Please help us by supporting the Naked Scientists

Adam's Paternity Leave continues, so we're going back to the well to pull an episode that feeds our Benbot passion. Patreon payments are frozen for the time being. A few resourceful new Munchies have figured out a work-around where you can join as a free member and upgrade from there to a paid account which charges you for one month and unlocks the back catalog behind the respective tier of the paywall. After that first payment, you won't be charged again until we're dropping new content (which we'll warn everyone is coming), so if you want more of this it can be had, along with access to the fully uncut episodes from 100 to present and Movie Club episodes.Sometimes the Randomizer giveth; sometimes it taketh away. It's sort of like SVU that way. This week it gave an episode that takes us all on a wild ride from a stairwell in Chelsea to the grim realities of life in the Democratic Republic of Congo. Along the way, jealousy abounds, Benbot enjoy a romantic candlelit dinner, Adam breaks down the past 150 years of strife in the Congo, Amazing Grace and Chuck is deduced to have done some ripping from the headlines, no one wants to believe our victim—Lainie McCallum, played by Diora Baird—and a cut hand yields some unexpected outcomes. The Munchie Boys tackled “Witness” (S11E16), so hold on to your butts.Music:Divorcio Suave - "Munchy Business"Thanks to our gracious Munchies on Patreon: Jeremy S, Jaclyn O, Amy Z, Diana R, Tony B, Zak B, Barry W, Drew D, Nicky R, Stuart, Jacqi B, Natalie T, Robyn S, Christine L, Amy A, Sean M, Jay S, Briley O, Asteria K, Suzanne B, Tim Y, John P, John W, Elia S, Rebecca B, Lily, Sarah L, Melsa A, Alyssa C, Johnathon M, Tiffany C, Brian B, Kate K, Whitney C, Alex, Jannicke HS, Roni C, and Nourhane B - y'all are the best!Be a Munchie, too! Support us on Patreon: patreon.com/munchmybensonBe sure to check out our other podcast diving into long unseen films of our guests' youth: Unkind Rewind at our website or on YouTube, Apple Podcasts, or wherever you listen to podcastsFollow us on: BlueSky, Facebook, Instagram, Threads, and Reddit (Adam's Twitter/BlueSky and Josh's BlueSky/Letterboxd/Substack)Join our Discord: Munch Casts ServerCheck out Munch Merch: Munch Merch at ZazzleCheck out our guest appearances:Both of us on: FMWL Pod (1st Time & 2nd Time), Storytellers from Ratchet Book Club, Chick-Lit at the Movies talking about The Thin Man, and last but not least on the seminal L&O podcast …These Are Their Stories (Adam and Josh).Josh debating the Greatest Detectives in TV History on The Great Pop Culture Debate Podcast and talking SVU/OC and Psych (five eps in all) on Jacked Up Review Show.Visit Our Website: Munch My BensonEmail the podcast: munchmybenson@gmail.comThe Next New Episode Once We're Back from Adam's Paternity Leave Will Be: Season 16, Episode 14 "Intimidation Game"Become a supporter of this podcast: https://www.spreaker.com/podcast/munch-my-benson-a-law-order-svu-podcast--5685940/support.

Henrico officials issue 18-page report proposing changes to data center development; Henrico Doctors' Hospital dealt with MRSA outbreak in NICU unit for three years; former Henrico Doctors' Hospital nurse accused of abusing infants is stripped of her nursing license; county reports incidents of people posing as Public Utilities employees.Support the show

Exposing the truth behind Krystal Clark and the life-threatening medical neglect she now endures inside Michigan's Huron Valley Correctional Facility. After testing positive for fungi and mold in her lungs, developing visible mold growth in her ears, and receiving a life-threatening MRSA diagnosis, Krystal has been denied critical medical care. Despite MDOC's own healthcare policies, her condition continues to be ignored, raising urgent questions about neglect, accountability, and systemic abuse within Michigan's prison system.Join us as we expose the truth, amplify Krystal's voice, and demand justice.This isn't just her fight — it's ours. https://linktr.ee/fightingforkrystalclark***Turning A Moment Into A Movement Podcast MISSION:To bring awareness, organize, and create content that will be a resource that will aide families, communities, and those seeking Justice for WRONGFUL CONVICTIONS and Injustice. ...and advocating for Justice & Exoneration for GERARD HAYCRAFT. www.change.org/Justice4Gerardhttps://linktr.ee/turningamomentintoamovement

In the second episode of our miniseries on infectious disease diagnostics, Jonathan is joined by molecular epidemiologist Rodney Rohde, Regents' Professor at Texas State University, USA. Together, they explore diagnostic innovations in the fight against antimicrobial resistance, gaps in zoonotic disease detection, and the persistent challenge of vaccine hesitancy. Timestamps: 00:00 – Introduction 01:45 – Breakthroughs in molecular diagnostics 08:30 – Diagnostic tools to combat superbugs 14:18 – Can bacteriophages replace antibiotics? 19:04 – Controlling rabies and hantavirus 28:33 – Diagnostic successes and failures from COVID-19 35:22 – How do we address vaccine hesitancy? 44:10 – Preparing for the next pandemic 47:03 – Rohde's three wishes for healthcare

Ep 101 - Can Cars Run On Water - The Stanley Meyer Story Welcome to this episode of Event Horizon. Today, we unravel the fascinating and controversial story of Stanley Meyer's water-powered car—a revolutionary invention he claimed could run on nothing but water. Born on August 24, 1940, Stanley Allen Meyer, alongside his twin brother Stephen, designed a device called the "water fuel cell." This so-called perpetual motion machine was said to replace gasoline with water, leading to incredible claims of a dune buggy journey from Los Angeles to New York on just 22 gallons of water.Meyer asserted that the U.S. government and military offered him millions to acquire his patent—offers he refused as he sought to commercialize his invention. However, in 1996, before production could begin, Meyer faced a shareholder lawsuit, and an Ohio court declared his claims fraudulent.Yet, the drama didn't end there. On March 21, 1998, while meeting potential investors at a local restaurant, Meyer drank a sip of cranberry juice and suddenly fled the table, clutching his throat. His chilling final words? “They poisoned me.” Was Stanley Meyer silenced for his groundbreaking technology, or was this a tragic coincidence? And do governments really have the power to seize revolutionary patents from private inventors? These burning questions and more await in this episode. Tune in to uncover the full story—and don't forget to subscribe!Join The Community Follow us on:Facebook at https://www.facebook.com/quantumAIradioTwitter (X) at @EventHo14339589Instagram at @EventHorizonEmail at mpeter1896@gmail.com   Subscribe To My Other Podcasts:Movie Reviews from the Edge - https://www.spreaker.com/show/movie-reviews-from-the-edgeThe Mark Peterson Show - https://www.spreaker.com/show/the_mark_peterson_show      Support the Show Did you know you can support the podcast by joining the Spreaker Supporter Club? For as little as $2.00 per month, you can help me grow the show and produce more episodes.  Go to the show page on Spreaker and click on the Supporter Club!     You can also make one-time donations at my CashApp or Paypal:CashApp - $mpeter1896PayPal – mpeter1896@gmail.com Buy My New Book I have a new book!  It is called Career Coaching Xs and Os: How To Master the Game of Career Development.  Transform your career trajectory with insider knowledge and actionable advice, all packed into one game-changing guide.     Get your copy on Amazon at https://a.co/d/f7irTMLSources:https://www.reddit.com/r/WeirdWheels/comments/t1ehiu/stanley_meyers_water_powered_car_the_car_was_said/?rdt=41987http://www.top-alternative-energy-sources.com/stanley-meyer.html https://slate.com/technology/2018/05/the-thousands-of-secret-patents-that-the-u-s-government-refuses-to-make-public.html https://tcct.com/news/2020/11/the-mysterious-death-of-stanley-meyer-and-his-water-powered-car/?srsltid=AfmBOooD5NB4hEtrCsmDcM3FpSnW_mVybUkGuMS_86mRrpPDhJ7IJhNUhttps://www.bbc.com/news/business-68534703 https://www.npr.org/2025/03/21/g-s1-55175/whistleblower-john-barnett-lawsuit-boeing#:~:text=The%20family%20of%20John%20Barnett,to%20take%20his%20own%20life.%22 https://www.seattletimes.com/business/whistleblower-josh-dean-of-boeing-supplier-spirit-aerosystems-has-died/https://www.nhs.uk/conditions/mrsa/#:~:text=MRSA%20usually%20lives%20harmlessly%20on,it%20spreads%20inside%20the%20body.Become a supporter of this podcast: https://www.spreaker.com/podcast/event-horizon--2860481/support.

Send us a textDwight Sheehan shares his journey from a 268-pound globo gym member to CrossFit affiliate owner, highlighting how an unexpected hospital stay changed his career trajectory and life path.• Started CrossFit in March 2021 after two gym members suggested he consider bodybuilding• Played offensive and defensive line in high school football, later becoming a high school coach• Lost significant weight in 2016, dropping from 268 pounds to 225 through running and diet changes• Developed a MRSA infection right before his first CrossFit comp • Decided to leave his unfulfilling mortgage job after his boss asked if he could work from the hospital• Took over CrossFit 717, growing membership from 65 to 110 members• Created "Nobody's Safe Athletics" as his coaching brand for individualized programming• Balances the dual challenges of being both a coach and owner• Preparing for the Master's Fitness Championships qualifier after placing fourth by half a point last year

A conversation with Rosie BartelNurturing the patient-physician partnership is the only way to heal healthcare.Sharing her lived experience with openness and honesty is Rosie Bartel, a patient advocate and survivor of preventable medical error. Since contracting MRSA after a routine knee replacement surgery, Rosie has channelled a hugely difficult and prolonged healthcare experience into a mission for systemic change.As she states, patient safety is a bipartisan issue, and we must ensure continued collaboration and communication between physicians, policymakers, executives and most importantly, patients themselves.——We spoke about Rosie's journey, why she believes patient advocacy is so important, the importance of breaking down silos that prevent communication, how patients can become their own advocates, and her solutions for developing relationships in healthcare that are rooted in trust.Follow me on Instagram and Facebook @ericfethkemd and checkout my website at www.EricFethkeMD.com. My brand new book, The Privilege of Caring, is out now on Amazon! https://www.amazon.com/dp/B0CP6H6QN4

Man Says He Visited Heaven, Met Jesus During Near-Death Experience Watch this video at- https://youtu.be/3FQmcCFZ8Ng?si=x4U0Eezqh21CuDDg CBN News 2.28M subscribers 123,685 views May 16, 2024 Randy Kay's "afterlife" experience still leaves him visibly emotional as he recounts details of visiting heaven, meeting Jesus, and returning to share his harrowing journey. Kay, author of the book, "Heaven Stormed: A Heavenly Encounter Reveals Your Assignment in the End Time Outpouring and Tribulation," told CBN News he was once a denier of near-death experience claims — until he faced his own purported heaven journey. He recalled his own afterlife experience, which began with a sore calf. At first, he thought he had strained a muscle, but while working out and going on a bike ride, his calf began to swell. "I was able to make it back home and then went to the doctor to get an anti-inflammatory prescription, and lo and behold, when I pressed my heel into the floor as the doctor had suggested, I collapsed," Kay said. "And I was rushed to the emergency room." It turns out, the pain and swelling were due to seven blood clots that had formed. He then contracted Methicillin-resistant Staphylococcus aureus (MRSA), a drug-resistant bacteria. "The doctor said I was a walking dead man," Kay said. "And then the septic shock which entered into my body caused a traffic jam in my vessels, my vascular system." The chaos landed Kay in a dire situation — one that he believes sent him to heaven. "Everything went dark initially and the next moment of recall, I was looking down on my body," he said. "I was being pulled by this light. I know that sounds cliche, almost, but it's absolutely true." Kay continued, "I was in a kind of very vague, ethereal space initially where I saw these figures in front of me, and they were warring against each other. There's no other way of putting it." After his return from his after-death experience, Kay discerned he was watching spiritual warfare play out. Regardless of what people choose to believe, Kay's physical body was dead at this point, making these memories and claims quite fascinating. "My heart had stopped," he said, noting that hospital records indicate he was clinically dead for 30 minutes and 49 seconds. During that time, Kay believes he was experiencing heaven, noting he was aware that her was himself but suddenly was seeing and visualizing the world quite differently. "I was seeing things, hearing things beyond which I would be able to do otherwise in my body," he said.

It was a recipe for disaster. In 2023, Stacey Grant was rushed to the hospital with a MRSA infection. It was in her bloodstream, in her lungs, and most likely around her heart. To say she dodged a bullet is an understatement. Because many do not. Cardiovascular disease kills more women than all forms of cancer combined and yet only 44% of women recognize that cardiovascular disease is their greatest health threat. On this episode of the HIListically Speaking Podcast, we're changing that for you and your heart.   CONNECT WITH STACEY http://www.mainlinevideostudio.com https://www.instagram.com/staceymgrant https://www.linkedin.com/in/staceygrant/ SUPPORT STACEY AS AN AHA WOMEN OF IMPACT https://bit.ly/4hUZS0o ⁣ Need a Podcast Mic - I'm Using Shure MV7+ Mic  ⁣ https://amzn.to/3ZBaXNm (Amazon)⁣   ⁣As an Amazon Associates I earn from qualifying purchases ⁣ ⁣ DISCOVER HAVENING TECHNIQUES TRAININGS & WORKSHOPS⁣ https://www.hilaryrusso.com/training   ⁣GET BRAIN CANDY DELIVERED TO YOUR INBOX⁣ ⁣ https://www.hilaryrusso.com/braincandy ⁣ BOOK HILARY FOR YOUR NEXT EVENT OR ATTEND!⁣ https://www.hilaryrusso.com/events⁣ ⁣ CONNECT WITH HILARY⁣ https://www.hilaryrusso.com⁣ https://www.linkedin.com/in/hilaryrusso⁣ https://www.instagram.com/hilaryrusso⁣ https://www.youtube.com/hilaryrusso⁣ https://www.hilaryrusso.com/podcast⁣ ⁣ MUSIC by Lipbone Redding⁣ https://www.lipbone.com/

Tuesday, February 25 - Host Doug Stephan and Dr. Ken Kronhaus of Lake Cardiology (352-735-1400) cover a number of topics affecting our health. First up, the severity of this year's flu, a drastic increase of adults being diagnosed with pneumonia and MRSA, and why getting more rest when you're sick is beneficial to your immune system, especially when going to work is only spreading your illness around. Then, the conversation shifts to Robert F. Kennedy Jr.'s confirmation as the Secretary of Health and Human Services and where he might start first in investigating harmful food ingredients and additives, the safety of childhood vaccines and anti-depressant drugs, harmful herbicides, and effects of electromagnetic radiation. Additionally, Doug and Dr. Ken discuss that latest information on the Avian Flu, why there is a rise in lung cancer amongst non-smokers, a connection in depression and long-term health issues relating to heart disease, a focus on the rise of gambling addiction, and the differences between weight-loss drugs and which Dr. Ken prefers. Lastly, Dr. Ken answers your questions, including how you would know you're low on Vitamin D, heart-healthy tips Dr. Ken shares with his own patients at his clinic in Mount Dora, FL, and why you need to keep up with regular checkups with your doctor and pay attention to any new symptoms you notice. Website: GoodDayHealthShow.comSocial Media: @GoodDayNetworks

By Walt HickeyWelcome to the Numlock Sunday edition.This week, I spoke to Olivia Walch, author of the brand-new book Sleep Groove: Why Your Body's Clock Is So Messed Up and What To Do About It.Olivia's a good friend of mine and I've been hearing about her research and her work for years, and now she's finally got a whole book diving into why ideal sleep is more than just the eight hours number we hear so much about. It's a delightful book with all sorts of cool insights that can have major impacts on your life and health. We spoke about the human body's numerous circadian rhythms, why sleep regularity is more important than sleep duration, and why permanent daylight saving time is a bad idea. Walch can be found at oliviawalch.com and the book can be found wherever books are sold.This interview has been condensed and edited. Olivia, thank you so much for coming on.I'm so delighted to be here.You are the author of the brand-new book Sleep Groove: Why Your Body's Clock Is So Messed Up and What To Do About It. It's a really, really fun book. It covers a lot of the science behind sleep and actually has some pretty surprising stuff in there for folks who are interested in their own sleep health.You have a really interesting story about how you even fell into being interested in the science behind sleep. You did a sleep study at some point in grad school that changed your life, it sounds like.Well, you knew me before then. We were in college together.Each diabolically bad at sleeping.I would give each of us a failing grade — you maybe a lower grade than me. I was bad, but you were exploring new horizons of bad, like with polyphasic sleep.I tried it once. It was such a bad idea.Maybe a D, D-minus. I knew when I went to grad school something had to change. I was not sleeping; I was not making new memories; I was getting sick. I got MRSA in college and I wonder all the time, was it because my immune system was like a frail Cheeto trying to hold the door closed to the germs? But at the time, I thought at college, you have to do everything. You have to be in every club and miss no opportunity for an experience. And I now remember no experiences from that time period.In grad school, I decided I was going to sleep more. I did, but I didn't actually notice that huge of a difference with fewer things filling my schedule, even though I was sleeping more. It was better, but it wasn't that much better. It took a sleep study in which I had to keep a really regular bedtime and researchers were spying on me. They would know if I didn't, because I was wearing a device, ye olde Jawbone, which is not even a thing anymore. For months, I went to bed at 11:30 every single night.The changes were so profound. I didn't just instantly fall asleep at 11:30, though that did happen. I got faster, I lost weight, skin conditions cleared up. In every dimension, my life was better. And the thing that had shifted was not really sleep duration, but sleep regularity.You get at this idea early in the book. There's this very common number that everybody associates with the right thing to do about sleep, which is that you should sleep for eight hours. The book goes the next level deeper, looks at some of the other dimensions of sleep, and it turns out that eight hours is good, that's a good thought to keep in your mind, but it's really the rhythm. What is the conceit here? Why are rhythms important when it comes to this stuff?Our understanding of sleep health is so fixated on duration that there's a creepypasta on Reddit that goes, "Oh, these Russians were kept awake and they went crazy." The creepypasta has always been funny to me because it's like, "Yeah, and after five days of no sleep, they started eating their own organs." (Spoilers for the Russian sleep experiment creepypasta.) Yet we've kept lots of people up for five days and they don't start eating their organs. We have this conception in our minds that losing sleep duration is going to be really bad. It's not good, but it also doesn't make you self-cannibalize after five days of no sleep.That definition of sleep health is woefully inadequate. The movement in the sleep field is higher dimensional. There are more things that matter to sleep health. There's this big, long list of things. People say you should think about how many times you wake up in the middle of the night, and you should think about how alert you feel during the day.All of those are great, but they're not memorable. People don't keep two things in their head, let alone five. I'm trying to get people to keep two, which is duration and regularity, as the latitude and longitude of sleep health. You don't say Madrid and New York are close together just because they have the same latitude; longitude also matters. You shouldn't say somebody who sleeps eight hours a night is healthy if they have horrible regularity. That's a case where they are probably pretty far from health, just like New York and Madrid are pretty far from each other.A lot of this comes down to circadian rhythms. What are they in your view? What kind of bodily processes are governed by them?The whole shebang. The problem with circadian rhythms is that their UI is terrible. People talk about the circadian rhythm, but that's not really right because circadian rhythms are plural. Sleep is under the subhead of circadian rhythms, but so is everything else in your body: when you're strongest, when you metabolize food, when your immune system peaks, when you repair DNA. There's this real problem. I think that because circadian rhythms are kind of everything, people just say, "You know, the rhythms." This leads to everyone who doesn't study this all day, every day, walking around having no idea what they are and just thinking it's probably the same thing as sleep.Your body has an internal clock, and it schedules things according to when it thinks you need to do more or less of them. That clock is set by your light exposure, and in modern life, we get light whenever we want it, which is not particularly traditional or natural.Circadian rhythms developed as a process because we live on Earth, right? We know there's a certain amount of daylight and when certain things should happen, and we evolved specifically to have a circadian rhythm.Yes. The circadian rhythm is so tuned to Earth that if you put us on a planet with 28-hour days, we probably wouldn't be able to adjust. We would basically continue to have close to a 24-hour period in our rhythms that would continue, even though the sun on this planet would be up and down at different times. It's baked into us, and it's the case that there's just stuff in your body at some times that isn't there at other times. The hormone melatonin, for example. If I made you spit into a tube right now, you would not have melatonin in your spit.We're speaking in the middle of the afternoon. It's very, very bright outside.No melatonin. But 10 hours from now? Different story. The thing to imagine is just a bunch of switches in your body getting flipped on and off depending on the time of day, which has massive implications for health, drug efficacy, how you feel, and people have lost their connection to that. Number one, we can have light whenever we want it, so our rhythms are squished relative to where they otherwise would be. But number two, I think we don't have a great way of talking about rhythmic health, which my book tries to address. I'm sure there's much better I can do and other people can do in the future, but this is my first stab at it.You get at this inflection point where so much of these functions are the result of, if not tens of thousands, then millions of years of evolutionary processes really locking us into a day/night process. Then you have the emergence of electricity, and a lot of your book reflects on how that's actually changed the way our bodies work, in ways we wouldn't ordinarily expect. What are some of those ways?I would say signs of rhythms having different effects on your body in the winter versus summer. Any study that reports on those, I'm always very cautious about, because I was involved in a study where we looked at Twitter patterns over the course of the year. We wanted to know if people tweeted differently at different times of the year in a way that reflected the sun and circadian rhythms, and we saw this pretty incredible trend where things seemed to really shift around the spring. Daylight saving time is happening then, the sun is changing, so you think, okay, maybe it's related to the sun.Then we dug a little more closely into the data and saw that the entire effect was just driven by people going on spring break. You would see that people tweeted later when they were on break because they were sleeping in. The fact that we have light available to us whenever we want it and we're not just sitting around in the dark at 6 p.m. in December with nothing to do means that we're in a sort of perpetual summer. We have light as late as we want, as long as we want, and that's stepping on these natural rhythms that would be emerging in the absence of that light.The title of the book is Sleep Groove, and sleep groove is actually a thing you talk about quite a bit in the book. It's getting locked into a really strong, robust, resilient rhythm, and there are lots of advantages to having that. What are some of the advantages that you have by having that rhythm, and what are some things that can go wrong if you don't?I would say you die sooner. This is a brand-new result, that sleep regularity predicts dying better than sleep duration, but it does. Again, this definition of sleep health being how long you sleep would say, okay, shoot for eight hours on average, it doesn't matter when, and you're good.But if you actually look to see what predicts whether you die, the people who have the worst sleep regularity are highly correlated with dying younger, and it keeps coming out. This is in the last 18 months that connections are coming out between sleep regularity and hypertension, diabetes, mood disorders. The data was all there, but people weren't really looking at sleep regularity. We also didn't have as textured tools for defining sleep regularity as we do now, so that's another reason why it's coming out. But things that can go wrong without sleep regularity are all those bad things I listed.I should say that those are all correlations. You could say, well, maybe stressed people die earlier, and they're also sleeping irregularly as a sign of their stress. Except we also have studies where you put people on weird light schedules and you can watch a melatonin rhythm that's really robust just go away. They go 24 hours without making melatonin, which is weird. You've basically flattened their rhythm altogether.The mental image I always have in my mind for modern life is that we've taken rhythms that would be really high and pronounced — like, hey, now's the time to fix your DNA so you don't get cancer. Let's fix all our DNA right now. It's really clear period for fixing DNA — and you've stepped on it. Now it's like, well, I don't know. I guess it's the time to fix DNA? Maybe I'll do a little bit of that.The science is emerging. I don't want to overstate it, but I think there's a strong theoretical case for why the quashing of circadian amplitude is tied to a lot of bad things. The good thing is that more melatonin means you sleep better, feel better — basically my life after doing that one study.What's a situation where you have a strong circadian amplitude? A lot of light during the day? How do you get there?You do the same exact thing every day. I should say, I'm going to speak from a theoretical perspective because a lot of the experiments haven't been run yet. It's my collaborators and me who are calling for amplitude to be the new thing we go after, because sleep regularity is just circadian amplitude wearing glasses and a mustache. They pick up the same thing.What the theory says will get you the maximum circadian amplitude is to have a super bright day and get tons of daylight during the day, and then have a really, really dark night, and copy and paste that over and over again. That's basically it. I'm always think I should add other things for people to do, but it boils down to that.One of the challenges why people haven't discovered this on their own is that that's actually really hard to do in practice. Light at night is super fun, and we also have to work, and often work is indoors where there's just not as much sunlight.It really does seem like a problem of modernity. We've always had a way to illuminate the night, for all intents and purposes, but there's a vast gulf of difference between a candle and an incandescent light bulb, and then there's an even bigger difference between an incandescent light bulb and a full room of fluorescent light. There's been this subtle shift that we didn't notice over time, but our bodies did.You're speaking my language. This is exactly it: the creeping of light into every aspect of our life. Also, because it literally doesn't have mass, it feels immaterial, right? What, the photons are going to get you?And I don't think they will on a short time span. You can absolutely have a bad night of sleep. You can absolutely have disrupted sleep. People cross time zones. But it does add up over a lifespan, which is why we see sleep regularity being a better predictor of mortality than sleep duration. If you're highly irregular over your whole life, all these rhythms that would otherwise have been high metabolism, high DNA repair, robust ability to sleep, become flat and crappy and you get an accumulation of risk.So, a lot of what we've talked about is that there are lots of negative things when you're out of that appropriately phased kind of sleep. There are actually some really good things about being very attuned to that, too. You write in the book about athletics, about medicine. What are some of the ways we can actually gain quite a bit through knowing about this?By having a better sense of what our circadian time is. Conflict of interest disclosure, I do have a startup that tries to do this, but we'll be able to time drugs so that they're maximally effective and as least toxic as they can be.People sometimes go, okay, timing drugs as in you take sleep medication before you go to sleep. Sure, okay. But what if there were a drug that sometimes made your tumor shrink and at other times made it grow faster? That's a paper that came out in the last year. People aren't thinking about this. They're thinking about a 10% variation over the course of the day. They're not thinking about how this person's glioblastoma treatment didn't work because they took dexamethasone at the wrong time, and they died months earlier.I think the simplicity of the idea has started to act as a reason for people to not do it. They think, well, if timing actually mattered, somebody would have figured it out already. I won't be the one who wastes a bunch of time rediscovering what everyone else has. My stance is that we're just beginning to scratch the surface of all the things that can be controlled by timing, and the magnitude of the effects we can see.Imagine the drug I mentioned that accelerated tumor growth sometimes and squished it at others is standard of care. Everybody gets it with this particular type of brain tumor that it was studied in. Imagine you're testing a new drug and oh, it seems to work in these patients but it doesn't work in these other patients. Must not be a very good drug, so it gets ditched. It could be that that entire efficacy difference was driven by when they were taking this standard-of-care drug that everybody takes according to the clock, according to their body's clock. If you could just control for that, you could get more drugs making it through clinical trials.You even made a point that there's a good shift happening between notes saying you should take this pill in the morning, you should take the pill at night, and changing that to say you should take this pill after waking up or take this pill before you go to sleep. It's getting better at adequately describing the bodily conditions you should take pharmaceuticals under.Right. If you're a shift worker, you could be waking up at 3 p.m., for instance, and morning could be the worst time for you. You should take it when you wake up. Then again, if you're a shift worker, your rhythms are so funky that — I might be biased here — you should be using Olivia's cool app to track your circadian rhythms and know when to take all these different things.But yes, circadian medicine is all about timing your pills before you go to bed or after you wake up. It's also this idea of introducing grooves where we've removed the groove. An example would be that you have a sick kid and you can't feed them, so you put them on total parenteral nutrition, or TPN. They're getting fed through an IV, and the standard for that is to either do it overnight or do it just continuously, 24 hours a day. But if you think about it, if our whole bodies are rhythmic and we expect some things at some times and not at other times, and you're feeding them constantly, that's like being in the light all the time, which we would consider to be torture. If you put somebody in constant light, they are miserable.These researchers just changed it so they gave TPN only during the day, when the kids are awake and their metabolism is up and running. They were able to leave the hospital on average four days earlier because they weren't being force fed like a foie gras goose overnight. So, it's not just sleep grooves: it's food grooves, it's activity grooves, it's mood grooves, it's all these things. Acknowledging that they're rhythmic will lead to people being healthier.The medical stuff can get a bit in the weeds, but I thought it was really informative when you talked about U.S. Olympians going to Japan. You reflected on when folks went to Japan and how they trained there. There's actually a lot of performance that was hypothetically not being unlocked because people weren't being attuned to their circadian peaks. Do you want to talk a little about that?I was reading what people who are Olympians posted on their Instagram, imagining that we were friends. I saw somebody in the weight lifting category be like, "Can't wait to go to Tokyo in two days to compete!" They were fully adjusted or entrained to U.S. time, and they were going to do this trip to Tokyo that was going to massively disrupt their circadian rhythms. Then they were going to compete shortly after landing.Probably the reason for that is because it's really expensive to go and leave your life for a long period of time, and weight lifting isn't the moneybags, the dollar sign, of Olympic sports. But that probably wasn't the best for optimizing performance, to wait until right before you're supposed to go on and then try and lift something really hugely heavy — though it could have been.The thing is, when you travel, you get tired and you undergo jet lag because your light exposure is changing, but you also have a circadian rhythm in performance where people tend to do best in the evening. Around 5 or 6 p.m., you're strong and fast and can run far and lift heavy things. If in Japan, you were supposed to compete at 10 a.m., maybe what you want to do is not adjust and be really careful about staying on your old time zone for the first day you're there, so that your body is at 6 p.m. during Japan's local time of 10 a.m.When it's most suited to compete.Exactly, to lift a big, heavy thing.Exciting. You wrote a little about how there are two big peaks for performance over the course of a given day. What are those?People tend to be alert in the morning, and then they have a second wave of alertness as the day winds down. The way we think about that is that there are two forces that combine to make you feel sleepy: There's how much hunger for sleep you've built up, and then there's your circadian clock basically shaping the gravity. How heavy is gravity for you right now?In the morning, after you get over this initial wave of grogginess, you have the first wave of alertness and that's because you don't have any hunger for sleep. Imagine you're biking, and you just started biking so you're feeling fresh, you're okay. You haven't accumulated feeling tired from biking. In the middle of the day, though, you have accumulated some fatigue. You've been doing stuff with your brain and the circadian clock is not saying it's a great time to be alert. People often get sleepy in the middle of the day, like you would be sleepy if you'd been biking for four hours.Then later in the day, the circadian clock comes in and says it's time for you to be awake. You need to get your act together before the sun goes down or you might die. That's like the road you're biking on sloping downward. It becomes easier. It doesn't take as much effort to stay awake; it doesn't take as much effort to pedal. Your circadian clock is like, great, be alert. Do stuff in the latter part of your day up until close to your habitual bedtime, when the road starts to swoop up again.Then you basically hit the wall of, it's 3 a.m. I want to die. Why am I staying up super late in the year 2009 next to my good friend Walter? What are we doing? You push through that and you get on the other side, and the road starts to slant down again.It was really cool to see, because this speaks to my experience of being sleep deprived and going over the swing set. It's really cool that circadian rhythm still holds, and that's why you get that second wind in the morning and sleep deprivation madness or whatever you want to call it. You do still see that swing hold even if you get more and more sleep weight accumulating.Exactly.I want to talk about some of the studies that you covered, because they're very, very interesting, but I also want to talk about some policy implications. Two things stuck out to me. One was the conversation about daylight saving time and potentially going either permanent DST or permanent standard time. The other one that was super interesting was basically how teenagers react to light and how we set school schedules. What are your insights on those two potential policy questions?Let's do DST first. This also has horrible UI. Nobody can figure out what they're saying when they talk about DST. So, standard time is brighter mornings, darker evenings. Standard time is what we're on in the winter when everyone's depressed and they're like, "It's 5 p.m. and it's dark. Stupid, stupid DST." That's actually standard time that's causing that. DST is darker mornings, lighter at night. DST is what we're on in the summer when we have lots of light even at 9 p.m. It's really bright at night.The thing most circadian scientists are going to tell you is that permanent standard time is best, then the current system where we switch, and then the last and least preferable is permanent DST. You might think, okay, but why isn't it just better to not switch? There's this penalty of everyone jet lagging themselves when we wake up an hour earlier or have to stay up an hour later when we do these transitions in the spring and the fall. The reason is because having the light late into the day in the summer, and especially having light in the afternoons and evenings in the winter and really, really dark mornings in the winter, is worse than the jet lag from transitioning. If we did permanent DST, where we have really dark mornings in the winter, it wouldn't just be a couple days of us all feeling jet lagged. It would be this chronic buildup of a messed up groove.One of the reasons why it's hard for people to concisely say why permanent DST is bad is because it's about rhythmic health. It's been argued, hey, if you want to maximize the amount of hours that we have really bright light during the daytime periods where people are normally awake, DST is really good for that, because you have light until super late. Think about the summer.But do we want to maximize that?Exactly, because imagine the case that I alluded to when we were talking about the meal timing thing. If you're in bright light 20 hours a day like people are up in the Arctic, you have bad sleep. It's not because you don't know about blackout curtains; it's because you're not able to adjust to a rhythm that's all bright light, little bit of darkness. What permanent DST does is basically, in the wintertime, it forces a bunch of people to wake up in darkness, or dim light. They then stay in the dark for a really long time, and they get their bright light weighted way on the latter half of their day.I'm going to go into a long analogy, but I promise I'll bring it back down. Imagine a sidewalk with alternating yellow and black squares, and I give you a yellow shoe and a black shoe. I say, yellow shoe steps on the yellow square, black shoe steps on the black square. If it's well sized to your legs, you could just do that. You're like, awesome, this is great. But then I do something where I basically take the yellow squares and scoot them up into the black squares. Then I have this brownish, crappy blurring of light and dark: yellow, black, and the blur. If I go, "Okay, walk on this," what you have to do is take one big step with one foot and a little step with your other, and you have to repeat that over and over again.That's basically what DST is doing to you in the winter. If we were to go to that in the winter, you'd wake up in the darkness, but then you'd get light later in the day. It makes it so that your rhythms are thrown off. You wake up with a bunch of melatonin in your body. It's like everybody's popping melatonin pills first thing, if you were to do permanent DST.If you're sitting here thinking, "I'm not convinced by her arguments around stepping on yellow tiles with yellow shoes and black tiles with black shoes," the most compelling reason is the fact that we literally tried this. We tried DST in the winter. We didn't even make a year. Russia tried it in the last decade — they made it three years and they bailed. People have tried DST in the winter and we all think it sucks. Meanwhile, Arizona has been on standard time all year since the 1960s and they're going strong.They seem really thrilled with their situation in Arizona.They're pretty happy. So, moral of the story, the current system would be better than having super dark mornings in the winter, which is what permanent DST would be. But I don't really care that much because I'm so convinced that if we try this again, we'll be like Russia in 2014 and bail. We'll be like us in the '70s and bail. We just need to, as a generation, collectively experience it and realize, oh yeah, this is why DST sucks.The old knowledge has been lost. We must relearn it.We'll relearn it and we'll say, no, we're never going to make this mistake again. And then in 50 years, we'll make it again.People always want the optimization of, I want more sleep. I want eight hours of sleep. I want the most sleep I can possibly get, or I want the most light I can possibly get. It seems like that's a trap. I completely understand why people get into that position, because I like light and I like sleep, but just realistically, if you're seeing how much of this governs the rhythm of lots of different processes that are more sophisticated than just enjoying seeing bright things, it's a real shock to the system.Human brains are just not wired to think rhythmically. It's like if you're in a math class and you're learning about Fourier series, to go extremely niche, really fast. It's not intuitive. People are wired to think, "More of thing good," and we're just less wired to think, well, it's good at some times and bad at other times.Very briefly, then, should kids be going to school as early as they currently go to school?No. At the same time, we also shouldn't make it so late, because what would happen if we made it really late is kids would just stay up later. There are diminishing returns, but now you have kids who are waking up at 5:30. That's absolutely what it would feel like for me to wake up at 3:30. It's cruel to them. There's this idea that, oh, we'll do DST. We'll do permanent DST so we don't have to switch, and then we'll also make school times an hour later.You've basically just got us back to where we started. You've made it so that they're going to be functionally popping a melatonin pill in the morning, just based on how much more melatonin is in their body when they wake up, and then you're letting them sleep in another hour. You cannot make both of those changes and act like you've changed anything. You at best maintain the status quo. My personal vote is we should do permanent standard time or keep the current system and make it so that schools for kids start later.The book is full of really, really interesting studies. Some of them are fascinating, recent, breaking studies that, like you mentioned earlier, reveal incredible things about the link between these biorhythms as well as pharmaceuticals and things like that. Some of them, however, are from a more swashbuckling age of discovery, and you cover a lot of really interesting sleep studies from the earliest days of sleep research. Do you have any favorites?In the book it probably comes across that I am so enamored with these old sleep studies, in part because they really underscore this point that if our definition of sleep health is only duration, it's insufficient. There are a bunch of peer-reviewed papers that went, yeah, this guy said he didn't want to sleep anymore, so he just didn't sleep for a week and we watched him. Actually, that's maybe my favorite. There's this guy who comes into a lab and is like, humans don't need to sleep and I can prove it. And then he just doesn't.They went, whoa, let him cook?Yeah, he might be on to something. In the paper, they're like, we tried to stop him but he said he was going to do it anyway, so we gave him a typewriter to see how bad he got at typing. The answer is, he got so bad at typing so fast that he just went, I can't do this. They didn't make him type anymore because it was too hard for his eyes. He got really snippy. People tend to hallucinate when you keep them up all night. They get paranoid for days and days. But at the same time, he was functioning. He was able to, on the last day of the study, write a vaguely sexist acrostic poem. I have tried to understand this thing. It's confusing, but you get the sense that it's not positive toward women.The original no-sleep creepypasta.Seriously. Obviously, I'm glad we don't do studies like this now. We have human subject protections. Why would you need to run the study? They did that in the '30s and '60s, and it was weird. But the data's been out there for so long. The creepypasta levels of sleep deprivation, people can survive. You should not do it. You should absolutely not do it. It's a bad idea. But it's not an instantly fatal thing, like you pulled an all-nighter so watch out.The punchline is, unfortunately for human brains, which want very rapid feedback and instant gratification, the way to have sleep health is not something acute, like the absence of these all-nighters that are terrible for you, but rather the constant maintenance of healthy rhythms that are on the time scale of weeks, months and years, as opposed to hacks that you can do in one hour of your day.The book is called Sleep Groove: Why Your Body's Clock Is So Messed Up and What To Do About It. There are so many fascinating things in here, Olivia. Why don't you tell readers a little about where they can find the book and you.Sleep Groove is a book about the emerging science of sleep regularity and how it matters so much to your overall health, well-being, and how you feel at 3 a.m. in the morning. You probably feel pretty bad; my book will explain why. You can find it where books are sold, including Amazon and your local independent bookseller. There's also an audiobook coming out next month.Oh, fun. That's great. Thanks so much for coming on, Olivia.Thanks for having me.Edited by Susie Stark.If you have anything you'd like to see in this Sunday special, shoot me an email. Comment below! Thanks for reading, and thanks so much for supporting Numlock.Thank you so much for becoming a paid subscriber! Send links to me on Twitter at @WaltHickey or email me with numbers, tips or feedback at walt@numlock.news. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.numlock.com/subscribe

In this episode of the Micro Binfie Podcast, host Andrew Page takes listeners to the heart of the microbial genomics hackathon in Bethesda, Maryland, for an engaging conversation with special guest Megan Phillips, a PhD student from Emory University. Megan delves into her research on Staphylococcus aureus (MRSA), highlighting its fascinating dual nature as both a harmless and potentially serious pathogen. Megan discusses the complexities of tetracycline resistance, particularly focusing on plasmid-mediated mechanisms involving the pt181 plasmid. She explains how this plasmid's efflux pump, encoded by the gene tetK, contributes to variable resistance levels and the factors influencing MIC (Minimum Inhibitory Concentration) variability. Listeners will learn about the intricacies of plasmid copy numbers, their global spread across clonal complexes, and the occurrence of horizontal and vertical gene transfer. Throughout the episode, Megan shares insights on working with short-read sequencing data and the strategies she employs to detect plasmid presence using tools like BLAST. She also touches on the challenges and fascinating discoveries of tracking historical sample data and integrating findings from older research papers, showcasing her appreciation for the poetic style of scientific writing from the 1940s. For those interested in antimicrobial resistance, evolutionary microbiology, and the subtleties of bacterial genome analysis, this episode offers a compelling blend of technical details and engaging storytelling. Tune in to hear more about Megan's upcoming publications, her experiences navigating complex genomic data, and her thoughts on antimicrobial stewardship and historical perspectives on drug resistance.

How can cutting-edge air decontamination technology reshape healthcare and reduce infections? In today's episode of Tech Talks Daily, we explore this question with Dr. Deborah Birx, Chief Medical & Science Advisor at ActivePure Medical and former White House Coronavirus Response Coordinator, and Amy Carenza, Chief Commercial Officer at ActivePure. Together, they discuss how ActivePure's innovative technology is transforming air and surface purification in healthcare and beyond. ActivePure's advanced photohydrolysis technology, built on principles originally developed by NASA, replicates natural outdoor air purification indoors. Unlike traditional cleaning or filtration methods, this FDA-cleared Class II medical device offers continuous protection in occupied spaces, achieving remarkable results: a 96-99% reduction in MRSA and a 70% decrease in total healthcare-associated infections (HAIs). Dr. Birx and Amy explain how this breakthrough technology deactivates pathogens in real time, effectively filling the gaps left by manual cleaning processes. The conversation delves into the broader implications of ActivePure's solutions, from reducing hospital stays and improving healthcare outcomes to applications in food production, energy-efficient air management, and even residential use. Dr. Birx shares insights from recent studies, including findings published in PLOS ONE and the Journal of Infection Control, which highlight the technology's safety and efficacy. Meanwhile, Amy Carenza discusses how ActivePure is driving innovation to meet operational, quality, and sustainability goals across various industries. As we look to the future, the discussion touches on upcoming advancements in infection prevention, particularly for multi-drug resistant organisms, and the potential for ActivePure's technology to align with efforts to reduce chemical exposures and improve overall public health. How do you see air decontamination technology shaping healthcare and other industries? Join us for this fascinating discussion and share your thoughts!

We are back with more exciting IDWeek 2024 content. In this episode, Breakpoints hostesses Drs. Erin McCreary, Julie Ann Justo, Jeannette Bouchard, and Megan Klatt highlight more of our favorite sessions and posters at IDWeek, this episode is a must listen if you are an IDWeek nerd like us! References: Perret et al. Application of OpenAI GPT-4 for the retrospective detection of catheter-associated urinary tract infections in a fictitious and curated patient data set. 10.1017/ice.2023.189 Wiemken et al. Assisting the infection preventionist: Use of artificial intelligence for health care–associated infection surveillance. 10.1016/j.ajic.2024.02.007 Leekha et al. Evaluation of hospital-onset bacteraemia and fungaemia in the USA as a potential healthcare quality measure: a cross-sectional study. 10.1136/bmjqs-2023-016831 Diekema et al. Are Contact Precautions "Essential" for the Prevention of Healthcare-associated Methicillin-Resistant Staphylococcus aureus? 10.1093/cid/ciad571 Martin et al. Contact precautions for MRSA and VRE: where are we now? A survey of the Society for Healthcare Epidemiology of America Research Network. 10.1017/ash.2024.350 Browne et al. Investigating the effect of enhanced cleaning and disinfection of shared medical equipment on health-care-associated infections in Australia (CLEEN): a stepped-wedge, cluster randomised, controlled trial. 10.1016/S1473-3099(24)00399-2 Protect trial: Decolonization in Nursing Homes to Prevent Infection and Hospitalization. 10.1056/NEJMoa2215254 Aldardeer et al. Early Versus Late Antipseudomonal β-Lactam Antibiotic Dose Adjustment in Critically Ill Sepsis Patients With Acute Kidney Injury: A Prospective Observational Cohort Study. 10.1093/ofid/ofae059 Schmiemann et al. Effects of a multimodal intervention in primary care to reduce second line antibiotic prescriptions for urinary tract infections in women: parallel, cluster randomised, controlled trial. 10.1136/bmj-2023-076305 Vernacchio et al. Improving Short Course Treatment of Pediatric Infections: A Randomized Quality Improvement Trial. 10.1542/peds.2023-063691 Advani et al. Bacteremia From a Presumed Urinary Source in Hospitalized Adults With Asymptomatic Bacteriuria. 10.1001/jamanetworkopen.2024.2283 Saif et al. Clinical decision support for gastrointestinal panel testing. 10.1017/ash.2024.15 Bekker et al. Twice-Yearly Lenacapavir or Daily F/TAF for HIV Prevention in Cisgender Women. 10.1056/NEJMoa2407001 Montini et al. Short Oral Antibiotic Therapy for Pediatric Febrile Urinary Tract Infections: A Randomized Trial. 10.1542/peds.2023-062598 Nielsen et al. Oral versus intravenous empirical antibiotics in children and adolescents with uncomplicated bone and joint infections: a nationwide, randomised, controlled, non-inferiority trial in Denmark. 10.1016/S2352-4642(24)00133-0 Kaasch et al. Efficacy and safety of an early oral switch in low-risk Staphylococcus aureus bloodstream infection (SABATO): an international, open-label, parallel-group, randomised, controlled, non-inferiority trial. 10.1016/S1473-3099(23)00756-9 AMIKINHAL: Inhaled Amikacin to Prevent Ventilator-Associated Pneumonia. 10.1056/NEJMoa2310307 PROPHY-VAP: Ceftriaxone to prevent early ventilator-associated pneumonia in patients with acute brain injury: a multicentre, randomised, double-blind, placebo-controlled, assessor-masked superiority trial. 10.1016/S2213-2600(23)00471-X AVENIR: Azithromycin to Reduce Mortality — An Adaptive Cluster-Randomized Trial. 10.1056/NEJMoa2312093 Thomas et al. Comparison of Two High-Dose Versus Two Standard-Dose Influenza Vaccines in Adult Allogeneic Hematopoietic Cell Transplant Recipients. 10.1093/cid/ciad458 Schuster et al. The Durability of Antibody Responses of Two Doses of High-Dose Relative to Two Doses of Standard-Dose Inactivated Influenza Vaccine in Pediatric Hematopoietic Cell Transplant Recipients: A Multi-Center Randomized Controlled Trial. 10.1093/cid/ciad534 Mahadeo et al. Tabelecleucel for allogeneic haematopoietic stem-cell or solid organ transplant recipients with Epstein-Barr virus-positive post-transplant lymphoproliferative disease after failure of rituximab or rituximab and chemotherapy (ALLELE): a phase 3, multicentre, open-label trial. 10.1016/S1470-2045(23)00649-6 Khoury et al. Third-party virus-specific T cells for the treatment of double-stranded DNA viral reactivation and posttransplant lymphoproliferative disease after solid organ transplant. 10.1016/j.ajt.2024.04.009 Spec et al. MSG-15: Super-Bioavailability Itraconazole Versus Conventional Itraconazole in the Treatment of Endemic Mycoses—A Multicenter, Open-Label, Randomized Comparative Trial. 10.1093/ofid/ofae010

DON MOXLEY is the Sport Science Director at Stemregen, a leader in stem cell science-backed supplements. Driven by a personal mission to help people make necessary changes to alleviate suffering and enhance the well-being of all, he leverages his experience as an athlete, sports scientist, and educator to advance human performance and longevity. Whether he's sharing insights on a podcast, presenting cutting-edge research on stem cells and performance at a wellness conference, or offering practical advice on living an active and fulfilling life, Don makes the science of stem cells and longevity both accessible and actionable.  A former captain and Big Ten Champion with the Ohio State University wrestling team, he also served as the university's first sport scientist. He helped athletes track their progress in strength, cardiovascular fitness, and resilience training, leading to the team's national title and three Big Ten Championships. Throughout his career, Don has guided athletes to remarkable success, including two Olympic medals, four World Championships, seven National Championships, and 23 All-American honors.   Work With Me: Mineral Balancing HTMA Consultation: https://www.integrativethoughts.com/category/all-products  My Instagram: @integrativematt My Website: Integrativethoughts.com   Advertisements:   Viva Rays: Use Code ITP for a Discount https://vivarays.com/   Zeolite Labs Zeocharge: Use Code ITP for 10% off https://www.zeolitelabs.com/product-page/zeocharge?ref=ITP Magnesium Breakthrough: Use Code integrativethoughts10 for 10% OFF https://bioptimizers.com/shop/products/magnesium-breakthrough Just Thrive: Use Code ITP15 for 15% off https://justthrivehealth.com/discount/ITP15 Therasage: Use Code Coffman10 for 10% off https://www.therasage.com/discount/COFFMAN10?rfsn=6763480.4aed7f&utm_source=refersion&utm_medium=affiliate&utm_campaign=6763480.4aed7f   Chapters: 00:00 Introduction to Don Moxley and StemRgen 05:53 The Role of Stem Cells in Recovery 15:02 The Importance of Staying Active 20:20 The Science Behind Stem Regen 28:37 Exogenous Stem Cells vs. Natural Supplements 35:21 The Power of Hyperbaric Therapy 40:37 The Importance of Longevity and Vitality 49:18 Exploring Stem Cells and Their Applications 56:01 The Importance of Micronutrients 01:01:19 Personalized Health and Optimization   Takeaways: HRV is a crucial indicator of recovery and performance. Stem cells play a vital role in the body's healing process. Aging leads to a decline in stem cell production. Staying active is essential for longevity and health. Stem Regen can enhance the body's natural healing abilities. Exercise stimulates the release of beneficial molecules like BDNF. Natural supplements can be more accessible than exogenous stem cell treatments. Maintaining a healthy lifestyle can improve overall well-being. The body responds better to gradual increases in stem cell circulation. It's important to be cautious with supplements and their certifications. Hyperbaric therapy can provide significant relief from chronic pain. STEM Regen protocol led to a rapid recovery from knee pain. Inflammation is a major barrier to healing and performance. Longevity is about feeling good and being active at any age. Hormone replacement therapy can be a natural part of health optimization. Nutrition quality is often compromised in industrial food production. Personalized health strategies are essential for optimal performance. Micronutrients play a critical role in cellular health and recovery. Understanding your body's needs is key to thriving as you age. Supplementation can help address deficiencies in modern diets.   Summary: In this conversation, Matthew Coffman interviews Don Moxley, an expert in exercise physiology and stem cell research. They discuss the importance of heart rate variability (HRV) as a key performance indicator for health and recovery, the role of stem cells in healing and recovery, and how aging affects stem cell production. Moxley shares insights on the benefits of staying active and the significance of supplements like StemRgen in enhancing recovery and performance. The discussion also touches on the differences between exogenous stem cells and natural supplements, emphasizing the importance of a holistic approach to health and wellness. In this conversation, Don Moxley shares his personal journey of overcoming significant health challenges, including a serious knee injury and subsequent MRSA infection. He discusses the transformative effects of hyperbaric therapy and the STEM Regen protocol, which helped him regain mobility and reduce inflammation. The conversation also delves into the importance of longevity, hormone replacement therapy, and the role of nutrition in optimizing health and performance. Moxley emphasizes the need for personalized health strategies and the significance of micronutrients in achieving overall well-being.  

To have your question featured in a future video, please email: questions@drmdc.health

TWiM explains how ticagrelor alters the membrane of S. aureus and enhances the activity of vancomycin and daptomycin without eliciting cross-resistance, and the development of a novel continuous disinfectant technology that decreases healthcare-associated infections in ICUs by 70%. Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson. Become a patron of TWiM. Links for this episode Ticagrelor and S. aureus (mBio) Novel disinfectant technology (Am J Inf Control) UVC-LED to inactivate foodborne pathogens (Appl Envir Micro) UV disinfection systems (ACS Photonics) High-touch surfaces in specialized patient care area (CDC) Take the TWiM Listener survey! Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv  

Contributor: Taylor Lynch, MD Educational Pearls: What is neutropenic fever? Specific type of fever that is seen in cancer patients and other patients with impaired immune systems These patients are highly susceptible to infection Typically occurs 7-10 days after the last chemotherapy dose, this is when the immune system is the weakest It is useful to know the specific type of malignancy. For example, heme malignancies (ALL, AML, etc.) have more intense chemo and are at higher risk of neutropenic fever To qualify as a neutropenic fever, a patient must have one recorded temperature greater than 38.3 degrees C or be over 38 degrees C for one hour. The severity of the neutropenic fever is established by the absolute neutrophil count. Abs neutrophil count under 1500 is mild, less than 1000 is moderate, less than 500 is severe. Also look at monocytes (cell that becomes a macrophage). Less than 200 is very concerning What is the workup and treatment? Obtain a panculture (culture blood from both arms and all indwelling lines), obtain urine culture, and get a chest x-ray. Do not preform a rectal exam or obtain a rectal core temperature. This could cause bacteremia. Treat with Cefepime (broad range and includes pseudomonas but not MRSA). If there is concern for MRSA add vancomycin. Admit with Neutropenic precautions (gowns, gloves, mask, positive pressure room) References Peseski, A. M., McClean, M., Green, S. D., Beeler, C., & Konig, H. (2021). Management of fever and neutropenia in the adult patient with acute myeloid leukemia. Expert review of anti-infective therapy, 19(3), 359–378. https://doi.org/10.1080/14787210.2020.1820863 Zimmer, A. J., & Freifeld, A. G. (2019). Optimal Management of Neutropenic Fever in Patients With Cancer. Journal of oncology practice, 15(1), 19–24. https://doi.org/10.1200/JOP.18.00269 Summarized by Jeffrey Olson, MS3 | Edited by Meg Joyce & Jorge Chalit, OMS3  

Brianna Lapaglia and Grace O'Malley are being wicked weird and creepy on today's episode. Grace recaps her sold out comedy show while Brianna shares her night out in Philly. Spoiler alert: Brianna has MRSA brain and Grace is dreaming throughout this entire episode! Enjoy! 00:00 Grace's Cough 1:40 Grace's Comedy Show 4:05 Brianna's time to Philly 10:40 Flash Flood Warning 12:55 Grace's Mom is a Heckler 18:05 Billy Joel 21:30 Cousin Seano Gimme My Money 23:00 Instigators Premiere Recap 29:35 Brianna has MRSA 33:00 Yucky Stuff 38:30 SPOILER ALERT 40:00 Brianna's WIFI Guy 43:25 Smokeshows 45:00 MRSA Brain Conversation ---------- SUPPORT THE SHOW: Go to drinkpiratewater.com to find Pirate Water in a location near you! Download the Gametime app or go to https://gametime.co, enter your email, and redeem code PLANBRI for $20 off your first purchase (terms apply). Use code BRI15 on https://HustleButter.com for 15% off your order. Head to Sunglass Hut and discover the special selection of shades in store and online at https://sunglasshut.com.You can find every episode of this show on Apple Podcasts, Spotify or YouTube. Prime Members can listen ad-free on Amazon Music. For more, visit barstool.link/planbri